A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Pomolic acid 28-O-beta-D-glucopyranosyl ester is a natural triterpenoid found in the root of Sanguisorba officinalis. Synonyms: 1-O-[(3β)-3,19-Dihydroxy-28-oxours-12-en-28-yl]-β-D-glucopyranose. Grade: >96%. CAS No. 83725-24-0. Molecular formula: C36H58O9. Mole weight: 634.9.
Pomolic acid β-D-glucopyranosyl ester
Pomolic acid β-D-glucopyranosyl ester. Group: Biochemicals. CAS No. 83725-24-0. Pack Sizes: 5mg. US Biological Life Sciences.
A cell-permeable stilbene derivative that serves as an aryl hydrocarbon receptor (AhR) and acts as a highly specific and potent inducer of paraoxonase 1 (PON1). Shown to be a better activator of PON1 mRNA (EC50=1uM) and inducer of PON1 enzymatic activity (>3-fold at 5um) when compared to resveratrol. However, it is devoid of any activity against estrogen receptors and is not shown to inhibit activity of tyrosine kinases. Also shown to antagonize the effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on cytochrome P4501A1 (CYP1A1). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Ponatinib (AP24534) is an orally active multi-targeted kinase inhibitor with IC 50 s of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM, and 5.4 nM for Abl , PDGFRα , VEGFR2 , FGFR1 , and Src , respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AP24534. CAS No. 943319-70-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12047.
Ponatinib-[d8]
Ponatinib-[d8] is the labelled analogue of Ponatinib, which is a novel, potent multi-target inhibitor of Abl, PDGFRα, VEGFR2, FGFR1 and Src with IC50 of 0. 37 nM, 1. 1 nM, 1. 5 nM, 2. 2 nM and 5. 4 nM, respectively. Synonyms: Ponatinib D8; 3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methyl-1-piperazinyl-2,2,3,3,5,5,6,6-d8)methyl]-3-(trifluoromethyl)phenyl]-benzamide. Grade: 95% by HPLC; 95% atom D. CAS No. 1562993-37-6. Molecular formula: C29H19D8F3N6O. Mole weight: 540.61.
Ponatinib, Free Base (AP24534)
Ponatinib is a novel potent, orally available small molecule multitargeted kinase inhibitor. Ponatinib inhibits both native and mutant BCR-ABL. Ponatinib is used in the treatment of chronic myeloid leukemia (CML) with BCR-ABL kinase inhibitors. Ponatinib is the active ingredient in the drug product sold under the trade name Iclusig®, currently approved in at least one country for use in patients with chronic myeloid leukemia (CML) and Philadelphia chromosome positive (Ph+) acute lymphoblastic leukemia. Group: Biochemicals. Alternative Names: 3- (2-Imidazo[1, 2-b]pyridazin-3-ylethynyl) -4-methyl-N-[4-[ (4-methyl-1-piperazinyl) methyl]-3- (trifluoromethyl) phenyl]benzamide; AP 24534; Iclusig. Grades: Highly Purified. CAS No. 943319-70-8. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C29H27F3N6O, Molecular Weight: 532.56. US Biological Life Sciences.
Worldwide
Ponatinib HCL
Ponatinib hydrochloride is the hydrochloride salt of ponatinib. It is a potent pan inhibitor of tyrosine kinases, active in all single resistance ABL kinase mutations including the T315l mutation. It is approved for the treatment of chronic myeloid leukemia. It has a role as an antineoplastic agent and a tyrosine kinase inhibitor. It contains a ponatinib(1+). Alternative Names: Ponatinib hydrochloride;Ponatinib HCl;Iclusig;AP 24534 hydrochloride. CAS No. 1114544-31-8. Product ID: API1114544318. Molecular formula: C29H28ClF3N6O. Mole weight: 569. EINECS: 696-530-0. SMILES: CC1=C(C=C(C=C1)C(=O)NC2=CC(=C(C=C2)CN3CCN(CC3)C)C(F)(F)F)C#CC4=CN=C5N4N=CC=C5.Cl. Appearance: Solid powder. Standard: Facility GMP. Category: Anti-Tumor APIs.
Ponatinib hydrochloride
Ponatinib hydrochloride (AP24534 hydrochloride) is a hydrochloride of ponatinib. Ponatinib is an orally active multi-targeted kinase inhibitor with IC 50 s of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM, and 5.4 nM for Abl , PDGFRα , VEGFR2 , FGFR1 , and Src , respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AP24534 hydrochloride. CAS No. 1114544-31-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108766.
Ponatinib Impurity 2
Ponatinib Impurity 2. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1-(dibromomethyl)-4-nitro-2-(trifluoromethyl)benzene. CAS No. 122947-77-7. Molecular formula: C8H4Br2F3NO2. Mole weight: 362.93. Catalog: APB122947777.
Ponatinib Impurity 5
Ponatinib Impurity 5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1255099-13-8. Molecular formula: C11H10O2. Mole weight: 174.2. Catalog: APB1255099138.
Ponatinib Impurity 8
Ponatinib Impurity 8. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1001203-03-7. Molecular formula: C10H8O2. Mole weight: 160.17. Catalog: APB1001203037.
Ponatinib Tris-Hydrochloride
Ponatinib Tris-Hydrochloride. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1232836-25-7. Molecular formula: C29H30Cl3F3N6O. Mole weight: 641.95. Catalog: APB1232836257.
Ponceau 3r
Ponceau 3r. Uses: Designed for use in research and industrial production. Additional or Alternative Names: PONCEAU 3R;PONCEAU-3R STAIN;3-hydroxy-4-((2,4,5-trimethylphenyl)azo)-2,7-naphthalenedisulphonicacid,dis;3-hydroxy-4-((2,4,5-trimethylphenyl)azo)-2,7-naphthalenedisulphonicacid,disod;7-naphthalenedisulfonicacid,3-hydroxy-4-((2,4,5-trimethylphenyl)azo)-dis. Product Category: Heterocyclic Organic Compound. Appearance: Dark red crystals or red powder. CAS No. 3564-9-8. Molecular formula: C19H16N2Na2O7S2. Mole weight: 494.45. Purity: 0.96. IUPACName: disodium (4Z)-3-oxo-4-[(2,4,5-trimethylphenyl)hydrazinylidene]naphthalene-2,7-disulfonate. Density: g/cm³. Product ID: ACM3564098. Alfa Chemistry ISO 9001:2015 Certified.
Ponceau 3R
analytical standard. Group: Colorant standardsdyes & metabolitesdyes & metabolites. Alternative Names: FD&C Red No. 1, Usacert Red No. 1, D and C Red 15, Ext D and C Red No. 15, Japan Red 1, Ponceau 3R Lake, Japan Red 502, FD and C Red No. 1, Dolkwal Ponceau 3R, C.I. 16155, Maple Ponceau 3R, Ponceau 3R sodium salt, FDC Red 1, Disodium 3-hydroxy-4-[(2,4,5-trimethylphenyl)azo]-2,7-naphthalenedisulfonate,2,7-Naphthalenedisulfonic acid, 3-hydroxy-4-[(2,4,5-trimethylphenyl)azo]-, disodium salt (9CI), Scarlet F, Ponceau 3RN, Ponceau 3R (6CI).
Ponceau 4R
Ponceau 4R is a synthetic colorant that can be used for food coloring. Ponceau 4R is a strawberry red azo dye that can be used in a variety of foods, usually synthesized from aromatic hydrocarbons, and is stable to light, heat, and acids [1] [2]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Acid Red 18; New Coccine. CAS No. 2611-82-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-D0193.
Ponceau S (Acid Red 112) is a non-specific protein dye commonly used as a stain for Western blot. Ponceau S is used in an acidic aqueous solution that is compatible with antibody-antigen binding and dyes the proteins on the membrane red [1] [2] [3]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Acid Red 112. CAS No. 6226-79-5. Pack Sizes: 500 mg. Product ID: HY-12489.
Ponceau S (C.I.27195)
25g Pack Size. Group: Stains & Indicators. Formula: C22H12N4Na4O13S4. CAS No. 6226-79-5. Prepack ID 43797916-25g. Molecular Weight 760.57. See USA prepack pricing.
Ponceau S ≥90% (Dye content)
Ponceau S ≥90% (Dye content). Group: Biochemicals. Alternative Names: 3-Hydroxy-4[2-sulfo-4- (4-sulfophenylazo) phenylazo]-2, 7-naphthalenedisulfonic acid tetrasodium salt. Grades: Reagent Grade. Pack Sizes: 5g, 25g, 100g, 250g, 1Kg. US Biological Life Sciences.
Worldwide
Ponceau Solution 0.1 % (w/v) in 5% (w/v) acetic acid
5lt Pack Size. Group: Analytical Reagents, Biochemicals, Buffers, Diagnostic Raw Materials, Organics, Stains & Indicators. Formula: C22H12N4Na4O13S4. CAS No. 6226-79-5. Prepack ID 90029153-5lt. Molecular Weight 760.57. See USA prepack pricing.
Ponceau ss
Ponceau ss. Uses: Designed for use in research and industrial production. Additional or Alternative Names: C.I.Acid Red 150; PONCEAU SS; ACID RED 150. CAS No. 6226-78-4. Molecular formula: C22H14N4Na2O7S2. Mole weight: 556.48. Purity: Dye content, 80%. IUPACName: disodium (4Z)-3-oxo-4-[(4-phenyldiazenylphenyl)hydrazinylidene]naphthalene-2,7-disulfonate. Canonical SMILES: C1=CC=C(C=C1)N=NC2=CC=C(C=C2)NN=C3C4=C(C=C(C=C4)S(=O)(=O)[O-])C=C(C3=O)S(=O)(=O)[O-].[Na+].[Na+]. ECNumber: 228-318-7. Product ID: ACM6226784. Alfa Chemistry ISO 9001:2015 Certified.
Poncirin is isolated from Poncirus trifoliata with anti-inflammory activites. Poncirin significantly reduces mechanical hyperalgesia and allodynia in Complete Freunds Adjuvant (CFA)-induced inflammatory pain models [1]. Uses: Scientific research. Group: Natural products. CAS No. 14941-08-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N2258.
Poncirin
Poncirin. Group: Biochemicals. Alternative Names: Citrifolioside. Grades: Plant Grade. CAS No. 14941-08-3. Pack Sizes: 20mg. Molecular Formula: C28H34O14, Molecular Weight: 594.561. US Biological Life Sciences.
Worldwide
Ponericin-G1
Ponericin-G1 is an antibacterial peptide isolated from Pachycondyla goeldii. It has activity against fungi. Synonyms: Gly-Trp-Lys-Asp-Trp-Ala-Lys-Lys-Ala-Gly-Gly-Trp-Leu-Lys-Lys-Lys-Gly-Pro-Gly-Met-Ala-Lys-Ala-Ala-Leu-Lys-Ala-Ala-Met-Gln-NH2. Molecular formula: C148H239N43O33S2. Mole weight: 3212.93.
Ponericin-G2
Ponericin-G2 is an antibacterial peptide isolated from Pachycondyla goeldii. It has activity against fungi. Synonyms: Gly-Trp-Lys-Asp-Trp-Leu-Lys-Lys-Gly-Lys-Glu-Trp-Leu-Lys-Ala-Lys-Gly-Pro-Gly-Ile-Val-Lys-Ala-Ala-Leu-Gln-Ala-Ala-Thr-Gln-NH2. Grade: >96%. Molecular formula: C155H249N43O37. Mole weight: 3306.96.
Ponericin-G3
Ponericin-G3 is an antibacterial peptide isolated from Pachycondyla goeldii. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Molecular formula: C157H254N44O37S. Mole weight: 3382.09.
Ponericin-G4
Ponericin-G4 is an antibacterial peptide isolated from Pachycondyla goeldii. Synonyms: Asp-Phe-Lys-Asp-Trp-Met-Lys-Thr-Ala-Gly-Glu-Trp-Leu-Lys-Lys-Lys-Gly-Pro-Gly-Ile-Leu-Lys-Ala-Ala-Met-Ala-Ala-Ala-Thr-NH2. Molecular formula: C145H232N38O37S2. Mole weight: 3163.80.
Ponericin-G5
Ponericin-G5 is an antibacterial peptide isolated from Pachycondyla goeldii. Synonyms: Gly-Leu-Lys-Asp-Trp-Val-Lys-Ile-Ala-Gly-Gly-Trp-Leu-Lys-Lys-Gly-Pro-Gly-Ile-Leu-Lys-Ala-Ala-Met-Ala-Ala-Ala-Thr-Gln-NH2. Grade: >97%. Molecular formula: C138H228N38O33S. Mole weight: 2979.64.
Ponericin-G6
Ponericin-G6 is an antibacterial peptide isolated from Pachycondyla goeldii. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Gly-Leu-Val-Asp-Val-Leu-Gly-Lys-Val-Gly-Gly-Leu-Ile-Lys-Lys-Leu-Leu-Pro-NH2. Molecular formula: C86H156N22O20. Mole weight: 1818.33.
Ponericin G7
Ponericin-G7 is an antibacterial peptide isolated from Pachycondyla goeldii. It has activity against gram-negative bacteria and fungi. Synonyms: Gly-Leu-Val-Asp-Val-Leu-Gly-Lys-Val-Gly-Gly-Leu-Ile-Lys-Lys-Leu-Leu-Pro-Gly-NH2. Grade: >97%. Molecular formula: C88H159N23O21. Mole weight: 1875.38.
Ponericin-W-like 321
Ponericin-W-like 321 is an antimicrobial peptide found in Lychas mucronatus (Chinese swimming scorpion), and has antibacterial and antifungal activity. Synonyms: Phe-Gly-Ser-Leu-Phe-Ser-Leu-Gly-Ser-Lys-Leu-Leu-Pro-Ser-Val-Phe-Lys-Leu-Phe-Ser-Arg-Lys-Lys-Gln. Grade: ≥95%. Molecular formula: C130H208N32O31. Mole weight: 2715.29.
Ponericin-W-like 322
Ponericin-W-like 322 is an antimicrobial peptide found in Lychas mucronatus (Chinese swimming scorpion), and has antibacterial and antifungal activity. Synonyms: Phe-Gly-Ser-Leu-Phe-Ser-Leu-Gly-Ser-Lys-Leu-Leu-Pro-Thr-Val-Phe-Lys-Leu-Phe-Ser-Arg-Lys-Lys-Gln. Grade: ≥97%. Molecular formula: C131H210N32O31. Mole weight: 2729.31.
Ponesimod
Ponesimod (ACT-128800) is a potent, selective and orally active agonist of S1P 1 , with an IC 50 of 6 nM in a radioligand binding assay. Ponesimod activates S1P 1 -mediated signal transduction with high potency ( EC 50 =5.7 nM). Ponesimod can protect against lymphocyte-mediated tissue inflammation [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ACT-128800. CAS No. 854107-55-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10569.
Ponezumab
Ponezumab (PF-04360365) is a humanised anti-amyloid IgG2 monoclonal antibody. Ponezumab reduces Aβ levels in the central nervous system and improves performance in mice in various models of learning and memory. Ponezumab can be used in study of Alzheimer's disease [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: PF-04360365; RN 1219. CAS No. 1178862-65-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99216.
Pongamol
Pongamol. Group: Biochemicals. Grades: Highly Purified. CAS No. 484-33-3. Pack Sizes: 25g, 50g, 100g, 250g, 500g. Molecular Formula: C17H12O3. US Biological Life Sciences.
Worldwide
Pongamol
Pongamol (Lanceolatin C) is potent α-glucosidase inhibitor (IC 50 =103.5 μM) and has free-radical (DPPH) scavenging,antihyperglycemic, and antihyperglycemic activities [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Lanceolatin C. CAS No. 484-33-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-121811.
Ponicidin
Ponicidin is a natural diterpenoid compound found in the herbs of Isodon japonicus. Ponicidin shows immunoregulatory and anti-inflammatory functions. Ponicidin also exhibits the activities of anti-viral, anti-leukemi and anti-cancer. Synonyms: Rubescensin B. Grade: >98%. CAS No. 52617-37-5. Molecular formula: C20H26O6. Mole weight: 362.42.
Ponicidin
Ponicidin. Group: Biochemicals. Grades: Highly Purified. CAS No. 52617-37-5. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C20H26O6. US Biological Life Sciences.
Worldwide
Ponsegromab
Ponsegromab (PF 06946860) is a potent and selective humanized anti- GDF15 monoclonal antibody with anti-cachexia activity. Ponsegromab binds to GDF15 and prevents the binding of GDF15 to GFRAL , thereby blocking GDF15/GFRAL -mediated signaling. Ponsegromab can be used in the research of cancers [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: PF 06946860. CAS No. 2368950-15-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99241.
Pontacyl carmine 2b
Pontacyl carmine 2b. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2,7-naphthalenedisulfonicacid,5-(acetylamino)-4-hydroxy-3-[(2-methoxyphenyl)a;2,7-Naphthalenedisulfonicacid,5-(acetylamino)-4-hydroxy-3-[(2-methoxyphenyl)azo]-,disodiumsalt;PONTACYL CARMINE 2B;CI 18075;ACID VIOLET 12;disodium 5-(acetylamino)-4-hydroxy-3-. Product Category: Heterocyclic Organic Compound. CAS No. 6625-46-3. Molecular formula: C19H15N3Na2O9S2. Mole weight: 539.45. Product ID: ACM6625463. Alfa Chemistry ISO 9001:2015 Certified. Categories: 2,7-Naphthalenedisulfonic acid.
POPH. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (5-Terphenyl-1,3-phenylene)bis(diphenylphosphine oxide). Product Category: Organic Light Emitting Diode (OLED). CAS No. 1818448-28-0. Molecular formula: C48H36O2P2. Mole weight: 706.75 g/mol. Product ID: ACM1818448280. Alfa Chemistry ISO 9001:2015 Certified. Categories: Popham Colony.
POPPV
POPPV. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Poly(2,5-dioctyl-1,4-phenylenevinylene). Product Category: Organic Light Emitting Diode (OLED). CAS No. 808735-22-0. Molecular formula: (C24H38)n. Product ID: ACM808735220. Alfa Chemistry ISO 9001:2015 Certified. Categories: Pop-punk.
Poppy Seed Powder (Papaver Somniferum)
Poppy Seed Powder (Papaver Somniferum).
CA, FL & NJ
POPSO
100g Pack Size. Group: Analytical Reagents, Biochemicals, Buffers, Diagnostic Raw Materials. Formula: C10H22N2O8S2. CAS No. 68189-43-5. Prepack ID 90024505-100g. Molecular Weight 362.42. See USA prepack pricing.
POPSO Disodium salt
25g Pack Size. Group: Analytical Reagents, Biochemicals, Buffers, Diagnostic Raw Materials. Formula: C10H20N2Na2O8S2. CAS No. 108321-07-9. Prepack ID 48108075-25g. Molecular Weight 406.38. See USA prepack pricing.
POPSO Ultrapure
500g Pack Size. Group: Analytical Reagents, Biochemicals, Buffers. Formula: C10H22N2O8S2. CAS No. 68189-43-5. Prepack ID 16854530-500g. Molecular Weight 362.42. See USA prepack pricing.
POPSO Ultrapure
100g Pack Size. Group: Analytical Reagents, Biochemicals, Buffers. Formula: C10H22N2O8S2. CAS No. 68189-43-5. Prepack ID 16854530-100g. Molecular Weight 362.42. See USA prepack pricing.
POPy2
POPy2. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Phenyl-dipyrenylphosphine oxide. Product Category: Organic Light Emitting Diode (OLED). CAS No. 721969-93-3. Molecular formula: C38H23OP. Mole weight: 526.56 g/mol. Product ID: ACM721969933. Alfa Chemistry ISO 9001:2015 Certified. Categories: Poppy Playtime.
Porantherine
It is a polycyclic alkaloid obtained from the shrub Poranthera corymbosa. Synonyms: (1R,6aS)-3aβ,4,5,6,7,8,9,9a-Octahydro-9aβ-methyl-1H-1,6a-ethanopyrido[2,1,6-de]quinolizine; (1S,4R,7S,9R)-9-Methyl-8-azatetracyclo[5.5.3.01,8.04,9]pentadec-5-ene; (1R,3aS,6aS,9aR)-3a,4,5,6,7,8,9,9a-octahydro-9a-methyl-1H-1,6a-ethanopyrido[2,1,6-de]quinolizine. Grade: ≥95% by HPLC. CAS No. 33529-61-2. Molecular formula: C15H23N. Mole weight: 217.35.
Porcine Brain/Heart Infusion Powder
Porcine Brain/Heart Infusion Powder.
CA, FL & NJ
Porcine Collagen
Porcine Collagen.
CA, FL & NJ
Porcine dynorphin A(1-13)
Porcine dynorphin A (1-13) is a potent, endogenous κ opioid receptor agonist and is antinociceptive at physiological concentrations. Uses: Scientific research. Group: Peptides. Alternative Names: Dynorphin A Porcine Fragment 1-13. CAS No. 72957-38-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P0088.
Porcine dynorphin A (1-13) acetate
Porcine dynorphin A(1-13) acetate is an endogenous opioid peptide that preferentially activates κ opioid receptors. Synonyms: Dynorphin A Porcine Fragment 1-13 acetate; Dynorphin A (1-13) acetate; H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-OH.CH3CO2H; L-tyrosyl-glycyl-glycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-isoleucyl-L-arginyl-L-prolyl-L-lysyl-L-leucyl-L-lysine acetic acid; Dynorphin A (swine), 14-de-L-tryptophan-15-de-L-aspartic acid-16-de-L-asparagine-17-de-L-glutamine-, acetate (salt); Dynorphin A (pig), 14-de-L-tryptophan-15-de-L-aspartic acid-16-de-L-asparagine-17-de-L-glutamine-, acetate (salt); 1-13-Dynorphin A (swine) acetate. Grade: ≥95%. Molecular formula: C77H130N24O17. Mole weight: 1664.00.
Porcine Hypothalamus Powder
Porcine Hypothalamus Powder.
CA, FL & NJ
Porcine Liver Powder
Porcine Liver Powder.
CA, FL & NJ
Porcine Lymph
Porcine Lymph.
CA, FL & NJ
Porcine Pituitary (Whole)
Porcine Pituitary (Whole).
CA, FL & NJ
Porcn Inhibitor II, C59 (Wnt-C59, Wnt Pathway Inhibitor XVI, 2-(4-(2-Methylpyridin-4-yl)phenyl)-N-(4-(pyridin-3-yl)phenyl)acetamide)
A cell-permeable pyridinylphenyl-acetamide that is much more potent than IWP-2 in inhibiting MBOAT family member Porcupine-mediated Wnt palmitoylation (IC50 = 74 pM in STF reporter assays using Wnt3a-transfected HEK293). Shown to be effective against Porcn of murine and human, but not xenopus, species and potently inhibit the processing of both canonical and non-canonical Wnt subtypes. C59 is demonstrated to be orally active and effectively suppress MMTV-WNT1 tumor expansion in mice (5mg/kg & 10mg/kg p.o.) in vivo. Group: Biochemicals. Grades: Highly Purified. CAS No. 1243243-89-1. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Porcn Inhibitor III, IWP-L6 (IWPL6, Wnt Pathway Inhibitor XIX)
A cell-permeable pyridinyl-phenylacetamide that is reported to be 60-times more potent than IWP-2 in suppressing autonomous Wnt signaling in murine L-Wnt-STF fibroblasts (IC50 = 0.5nM) and 100-times more potent in blocking branching morphogenesis in cultured murine embryonic kidney (complete blockage at 50nM). Also shown to be at least twice as potent as TNKS inhibitor IWR-1 in preventing the regeneration of severed zebrafish tailfin and in inhibiting zebrafish embryo prosterior axis formation (Effective conc = 5uM). Its susceptibility to metabolization by serum carboxylesterase limits its in vivo use in rats and mice. Group: Biochemicals. Grades: Highly Purified. CAS No. 1427782-89-6. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?S?. US Biological Life Sciences.
Worldwide
Porfiromycin
Porfiromycin is a quinone antibiotic produced by Str. ardus NRRL 2817. It has anti-Gram-positive and negative bacteria activity. It can inhibit sarcoma-180, Ehrlich ascites carcinoma, L-1210, H leukemia (solid type). The dose of inhibiting KB cell protein synthesis is 0.5 μg/mL. It is a bioreductive DNA alkylating agent that preferentially kills hypoxic tumor cells relative to other aerobic counterparts. Synonyms: N-Methylmitomycin C; NSC-56410; U-14743; Methylmitomycin; Methyl mitomycin C; Regamycin; Mitiromycin D; Porphyromycin; (1aS,8S,8aR,8bS)-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-1,5-dimethylazirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione. Grade: >98%. CAS No. 801-52-5. Molecular formula: C16H20N4O5. Mole weight: 348.35.
Porfiromycin
Antibiotic substance isolated from a Streptomyces ardus fermentation broth. Antibacterial; antineoplastic. Group: Biochemicals. Alternative Names: (1aS, 8S, 8aR, 8bS) -6-Amino-8-[[ (aminocarbonyl) oxy]methyl]-1, 1a, 2, 8, 8a, 8b-hexahydro-8a-methoxy-1, 5-dimethylazirino[2', 3': 3, 4]pyrrolo[1, 2-a]indole-4, 7-dione; ENT 50825; Methyl Mitomycin C; Methylmitomycin; N-Methylmitomycin C; NCI 56410; NSC 56410; Porfiromycine; Regamycin; U 14743. Grades: Highly Purified. CAS No. 801-52-5. Pack Sizes: 1mg, 2mg. US Biological Life Sciences.