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| Product | Description | |
|---|---|---|
| Polyvinylpyrrolidone (PVP10), K29-32 Average Molecular Wt. 58,000 | Polyvinylpyrrolidone is a white powder. Compatible with a wide range of hydrophilic and hydrophobic resins. (NTP, 1992);Liquid;White or nearly white powder;YELLOW-TO-BROWN HYGROSCOPIC POWDER.;COLOURLESS-TO-YELLOW LIQUID.;White powder. Group: Polymers. CAS No. 9003-39-8. Product ID: 1-ethenylpyrrolidin-2-one. Molecular formula: 111.14g/mol. Mole weight: (C6H9NO)n;C6H9NO;C6H9NO. C=CN1CCCC1=O. InChI=1S/C6H9NO/c1-2-7-5-3-4-6 (7)8/h2H, 1, 3-5H2. WHNWPMSKXPGLAX-UHFFFAOYSA-N. |  |
| Polyvinylpyrrolidone solution | PVP has biocompatibility, low toxicity, adhesive characteristics, complexing stability, relatively inert behavior, and is resistant to thermal degradation. It is readily prepared by the polymerization of N-vinyl-2-pyrrolidone or by the Reppe synthesis technique. Uses: Polyvinylpyrrolidone solution (pvp) is also known as k60 and can be used in a variety of s such as biomedical, tissue engineering, and medical materials. Group: Hydrophilic polymershydrophobic polymers. Alternative Names: Povidone, Polyvidone. CAS No. 9003-39-8. Pack Sizes: 500 mL in glass bottle. Product ID: 1-ethenylpyrrolidin-2-one. Molecular formula: 111.14g/mol. Mole weight: (C6H9NO)n;C6H9NO;C6H9NO. C=CN1CCCC1=O. 1S/C6H9NO/c1-2-7-5-3-4-6(7)8/h2H, 1, 3-5H2. WHNWPMSKXPGLAX-UHFFFAOYSA-N. | |
| Poly(vinyl stearate) | Poly(vinyl stearate). Group: Polymers. Alternative Names: Polyvinyl stearate. CAS No. 9003-95-6. Product ID: ethenyl heptadecanoate. Molecular formula: 296.5g/mol. Mole weight: C19H36O2. CCCCCCCCCCCCCCCCC(=O)OC=C. InChI= 1S / C19H36O2 / c1-3-5-6-7-8-9-10-11-12-13-14-15-16-1 7-18-19 (20) 21-4-2 / h4H, 2-3, 5-18H2, 1H3. BSNVHSQCRJMJHZ-UHFFFAOYSA-N. 95%. | |
| Poly(vinyl stearate), | Poly(vinyl stearate). Group: Polymers. CAS No. 9003-95-6. Product ID: ethenyl heptadecanoate. Molecular formula: 296.5g/mol. Mole weight: C19H36O2. CCCCCCCCCCCCCCCCC(=O)OC=C. InChI= 1S / C19H36O2 / c1-3-5-6-7-8-9-10-11-12-13-14-15-16-1 7-18-19 (20) 21-4-2 / h4H, 2-3, 5-18H2, 1H3. BSNVHSQCRJMJHZ-UHFFFAOYSA-N. | |
| Poly(vinyl sulfate) potassium salt | The hydrophilic polymer contains polar or charged functional groups, making it soluble in water. Uses: These water-soluble polymers are a major class of polymers that have a wide range of applications, such as in drug delivery, gene delivery, protein delivery, self-assembly, surface modification, and catalysis. Group: Hydrophilic polymersself-assembly materials. CAS No. 26182-60-5. Product ID: potassium; ethenyl sulfate. Molecular formula: average Mw ~170,000. Mole weight: [CH2CH(OSO3K)]n. [K]OS(=O)(=O)OC=C. InChI=1S/C2H4O4S.K/c1-2-6-7(3, 4)5;/h2H, 1H2, (H, 3, 4, 5);/q;+1/p-1. WZAPMUSQALINQD-UHFFFAOYSA-M. | |
| Poly(vinyl sulfate) potassium salt, Mw ~170,000 | Poly(vinyl sulfate) potassium salt, Mw ~170,000. Group: Polymers. CAS No. 26182-60-5. Product ID: potassium; ethenyl sulfate. Molecular formula: 162.21g/mol. Mole weight: C2H3KO4S. C=COS(=O)(=O)[O-].[K+]. InChI=1S/C2H4O4S.K/c1-2-6-7(3, 4)5;/h2H, 1H2, (H, 3, 4, 5);/q;+1/p-1. WZAPMUSQALINQD-UHFFFAOYSA-M. | |
| Poly(vinylsulfonic acid, sodium salt) solution | Poly(vinylsulfonic acid, sodium salt) is a polymer that consists of repeating units of vinylsulfonic acid monomers, where each vinylsulfonic acid unit is neutralized with a sodium cation (Na+). Poly(vinylsulfonic acid, sodium salt) is an example of a polyelectrolyte, which is a type of polymer that contains ionizable groups along its chain. The presence of sulfonic acid groups (-SO3H) in this polymer provides it with strong acidic properties. However, when the polymer is neutralized with sodium ions, it becomes water-soluble and exhibits enhanced solubility and stability in aqueous solutions. Uses: Poly(vinylsulfonicacid, sodium salt) (pvsa) can be used: in the preparation of superabsorbent semi-ipn (interpenetrating polymer network) hydrogel. as a solid electrolyte for proton conduction in the fabrication of an all-solid-supercapacitor. as a crystallization controlling agent in the preparation of high-quality crystals of porous coordination polymers(cp). pvsa regulates not only the size and structure of the crystals but also their preference orientation, resulting in cp channel alignment in the bulk powdery state. Alternative Names: PVSA. CAS No. 9002-97-5. Molecular formula: (C2H3NaO3S)n. Mole weight: 130.098. Appearance: Liquid. Purity: 0.75. Canonical SMILES: [Na]OS(=O)(=O)C=C. Density: 1.267 g/mL at 25ºC. Catalog: ACM9002975. |  |
| Poly(vinylsulfonic acid, sodium salt) solution | The hydrophilic polymer contains polar or charged functional groups, making it soluble in water. Uses: These water-soluble polymers are a major class of polymers that have a wide range of applications, such as in drug delivery, gene delivery, protein delivery, self-assembly, surface modification, and catalysis. Group: Hydrophilic polymersself-assembly materials. Alternative Names: PVSA. CAS No. 9002-97-5. Product ID: sodium; ethenesulfonate. Molecular formula: 130.1g/mol. Mole weight: (C2H3NaO3S)n. [Na]OS(=O)(=O)C=C. 1S/C2H4O3S.Na/c1-2-6(3, 4)5;/h2H, 1H2, (H, 3, 4, 5);/q;+1/p-1. BWYYYTVSBPRQCN-UHFFFAOYSA-M. | |
| Polyvinylsulfuric acid potassium salt | Polyvinylsulfuric acid potassium salt. Group: Polymers. Alternative Names: sulfuricacid, monoethenylester, homopolymer, potassiumsalt; sulfuricacid, monovinylester, polymers, potassiumsalt; PVSK; POLYVINYL SULFATE POTASSIUM SALT; POLYVINYLSULFATE POTASSIUM SALT POLYMER; POLYVINYLSULFURIC ACID POTASSIUM SALT; POTASSIUM POLY(VINYLSULFATE); VIN. CAS No. 26837-42-3/26182-60-5. Product ID: potassium ethenyl sulfate. Molecular formula: 162.20612. Mole weight: C2< / sub>H3< / sub>KO4< / sub>S. C=COS(=O)(=O)[O-].[K+]. WZAPMUSQALINQD-UHFFFAOYSA-M. 96%. | |
| Poly(vinyltoluene-co-α-methylstyrene) | The polymer product is a hydrophobic material that is insoluble in water or other polar solvents. Uses: Adhesive, paint and lacquer additive. Group: Hydrophobic polymers. Alternative Names: Methylstyrene-vinyltoluene copolymer, α-Methylstyrene-vinyltoluene copolymer. CAS No. 9017-27-0. Pack Sizes: 1 kg in poly bottle. Product ID: 1-ethenyl-2-methylbenzene; prop-1-en-2-ylbenzene. Molecular formula: 236.4g/mol. Mole weight: [CH2CH(C6H4CH3)]x[CH2C(CH3)(C6H5)]y. CC(=C)c1ccccc1. Cc2ccc(C=C)cc2. Cc3cccc(C=C)c3. Cc4ccccc4C=C. 1S/2C9H10/c1-8(2)9-6-4-3-5-7-9; 1-3-9-7-5-4-6-8(9)2/h2*3-7H, 1H2, 2H3. OSBCHXNIHVRZCO-UHFFFAOYSA-N. | |
| Poly(vinyltoluene-co-alpha-methylstyrene) | Poly(vinyltoluene-co-alpha-methylstyrene). Group: Polymers. Alternative Names: Benzene,ethenylmethyl-,polymerwith(1-methylethenyl)benzene; ethenylmethyl-benzenpolymerwith(1-methylethenyl)benzene; POLY(VINYLTOLUENE-CO-ALPHA-METHYLSTYRENE); POLY(ALPHA-METHYLSTYRENE/METHYLSTYRENE); METHYLSTYRENE/VINYLTOLUENE COPOLYMER; POLY(VINYLTOLUENE-CO-. CAS No. 9017-27-0. Product ID: 1-ethenyl-2-methylbenzene; prop-1-en-2-ylbenzene. Molecular formula: 236.4g/mol. Mole weight: C18H20. CC1=CC=CC=C1C=C.CC(=C)C1=CC=CC=C1. InChI=1S/2C9H10/c1-8 (2)9-6-4-3-5-7-9; 1-3-9-7-5-4-6-8 (9)2/h2*3-7H, 1H2, 2H3. OSBCHXNIHVRZCO-UHFFFAOYSA-N. | |
| POM 1 | POM 1. Group: Biochemicals. Grades: Purified. CAS No. 12141-67-2. Pack Sizes: 50mg. US Biological Life Sciences. |  Worldwide |
| Pomaglumetad methionil hydrochloride | Pomaglumetad methionil hydrochloride (LY2140023 hydrochloride) is an orally active, methionine prodrug of the selective mGlu2/3 receptor agonist LY404039. Pomaglumetad methionil hydrochloride has the potential for schizophrenia research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY2140023 hydrochloride. CAS No. 635318-26-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105040C. |  |
| Pomalidomid-C6-PEG3-butyl-N3 | CuAAC & SPAAC Click Reactions. Group: Azides. CAS No. 2300178-66-7. Molecular formula: C29H40N6O8. Mole weight: 600.66. Catalog: CCR2300178667. | |
| Pomalidomide | Promotes degradation of transcription factors SALL4, IKZF1 and IKZF3. Synonyms: CC4047; CC 4047; CC-4047; Pomalidomide. Brand name: Pomalyst. Grades: ≥99% (HPLC). CAS No. 19171-19-8. Molecular formula: C13H11N3O4. Mole weight: 273.24. |  |
| Pomalidomide | Pomalidomide, the third-generation immunomodulatory agent, acts as molecular glue. Pomalidomide interacts with the E3 ligase cereblon and induces degradation of essential Ikaros transcription factors. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CC-4047. CAS No. 19171-19-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g; 5 g. Product ID: HY-10984. | |
| Pomalidomide | Pomalidomide is a thalidomide derivative, a potent inhibitor of TNF-α production. It is an antiinflammatory and antitumor agent used in the treatment of multiple myeloma. Group: Biochemicals. Alternative Names: 4-Amino-2-(2,6-dioxo-3-piperidinyl)isoindole-1,3-dione; 4-Amino-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione; Actimid; CC 4047; IMiD 3. Grades: Highly Purified. CAS No. 19171-19-8. Pack Sizes: 500mg, 1g, 5g. Molecular Formula: C??H??N?O?, Molecular Weight: 273.24. US Biological Life Sciences. | Worldwide |
| Pomalidomide 4'-alkylC4-acid | Pomalidomide 4'-alkylC4-acid (linker16) is a E3 Ligase Ligand-Linker Conjugate. Pomalidomide 4'-alkylC4-acid can be used for conjugation to a target protein ligand [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2225940-48-5. Pack Sizes: 50 mg; 100 mg; 250 mg. Product ID: HY-131886. | |
| Pomalidomide 4'-alkylC5-acid | Pomalidomide 4'-alkylC5-acid (Example 3) is an E3 ligase ligand-linker conjugate containing a Pomalidomide (HY-10984) based cereblon (CRBN) ligand and a linker. Pomalidomide 4'-alkylC5-acid can be used in the synthesis of PROTAC [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2225940-49-6. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-130737. | |
| Pomalidomide 4'-PEG3-azide | Pomalidomide 4'-PEG3-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide-based cereblon ligand and a linker. Pomalidomide 4'-PEG3-azide can be used for the synthesis of iRucaparib-TP3 (Compound 3). iRucaparib-TP3 is a highly efficient PARP1 degrader based on Rucaparib by using the PROTAC approach [1]. Pomalidomide 4'-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 2271036-46-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130652. | |
| Pomalidomide-amino-PEG4-NH2 hydrochloride | Pomalidomide-amino-PEG4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2331259-45-9. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-138859A. | |
| Pomalidomide-C2-NH2 | Pomalidomide-C2-NH2 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 17 can be connected to the ligand for protein by a linker to form PROTACs or SNIPERs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1]. Synonyms: 4-((2-aminoethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione; SCHEMBL17884390; TQP0427; Cereblon Ligand-Linker Conjugates 15; HY-128846; Pomalidomide-C2-NH2; Pomalidomide-alkylC2-amine; E3 ligase Ligand 17; 4-[(2-Aminoethyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione hydrochloride. Grades: > 98%. CAS No. 1957235-66-3. Molecular formula: C15H16N4O4. Mole weight: 316.31. | |
| Pomalidomide-C2-NH2 hydrochloride | Pomalidomide-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Cereblon Ligand-Linker Conjugates 15 hydrochloride. CAS No. 2305369-00-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-128846A. | |
| Pomalidomide-C4-NH2 | Pomalidomide-C4-NH2 is a synthetic E3 ligase ligand-linker conjugate that incorporates Pomalidomide-based CRBN ligands and linkers used in PROTAC technology. Synonyms: 4-((4-aminobutyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione; 4-[(4-Aminobutyl)amino]-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione; 4-[(4-Aminobutyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione; 1H-Isoindole-1,3(2H)-dione, 4-[(4-aminobutyl)amino]-2-(2,6-dioxo-3-piperidinyl)-; Thalidomide-NH-C4-NH2. Grades: ≥95%. CAS No. 1957236-34-8. Molecular formula: C17H20N4O4. Mole weight: 344.37. | |
| Pomalidomide Impurity 1 | Pomalidomide Impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 5054-59-1. Molecular Formula: C13H10N2O5. Mole Weight: 274.23. Catalog: APB5054591. |  |
| Pomalidomide Impurity 1 | An impurity of Pomalidomide which inhibits lipopolysaccharide (LPS) stimulated TNF-alpha release in human PBMC and in human whole blood with IC50 values of 13 nM and 25 nM, respectively. Grades: > 95%. Molecular formula: C16H10N2O6. Mole weight: 326.27. | |
| Pomalidomide Impurity 10 | An impurity of Pomalidomide which inhibits lipopolysaccharide (LPS) stimulated TNF-alpha release in human PBMC and in human whole blood with IC50 values of 13 nM and 25 nM, respectively. Grades: > 95%. Molecular formula: C10H16N2O4. Mole weight: 228.25. | |
| Pomalidomide Impurity 20 | Pomalidomide Impurity 20. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1001852-10-3. Molecular Formula: C13H11N3O7. Mole Weight: 321.25. Catalog: APB1001852103. | |
| Pomalidomide Impurity 27 | Pomalidomide Impurity 27. Uses: For analytical and research use. Group: Impurity standards. CAS No. 610-27-5. Molecular Formula: C8H5NO6. Mole Weight: 211.13. Catalog: APB610275. | |
| Pomalidomide Impurity 3 | An impurity of Pomalidomide which is a second generation immunomodulator and antineoplastic agent. Synonyms: Isoasparagine; 498-25-9; 3,4-Diamino-4-oxobutanoic acid; DL-Isoasparagine; DL-alpha-Asparagine; H-Asp-NH; H-Isoasn-OH; L-Isoasparagine; H-D-Isoasn-OH; D-Isoasparagine; 3,4-Diamino-4-oxobutyric acid; 3-amino-3-carbamoylpropanoic acid; alpha-asparagine; aspartic 1-amide; H-D-Asp-NH; 3-aminosuccinamic acid; 3,4-Diamino-4-oxobutanoic acid #; NSC528893; Aminobernsteinsaureamid; DL-aspartic 1-amide; aspartic acid 1-amide; NoName_589; Succinamic acid, 3-amino-; SCHEMBL1072994; SCHEMBL11049326; 3-amino-3-carbamoylpropanoicacid; CHEBI:49010; DTXSID90901471; PMLJIHNCYNOQEQ-UHFFFAOYSA-N; Butanoic acid, 3,4-diamino-4-oxo-; AKOS014226960; NSC 528893; NSC-528893; FT-0638751; FT-0697947; EN300-182732; Q27121435. Grades: > 95%. CAS No. 498-25-9. Molecular formula: C5H10N2O3. Mole weight: 146.15. | |
| Pomalidomide Impurity 3 | Pomalidomide Impurity 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2635-64-5. Molecular Formula: C13H13N3O5. Mole Weight: 291.26. Catalog: APB2635645. | |
| Pomalidomide Impurity 4 | An impurity of Pomalidomide which is an immunomodulatory antineoplastic agent for the treatment of multiple myeloma. Synonyms: DL-GLUTAMINE. Grades: > 95%. CAS No. 585-21-7. Molecular formula: C5H10N2O3. Mole weight: 146.15. | |
| Pomalidomide Impurity 4 | Pomalidomide Impurity 4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 918314-45-1. Molecular Formula: C13H13N3O5. Mole Weight: 291.26. Catalog: APB918314451. | |
| Pomalidomide Impurity 5 | An impurity of Pomalidomide which inhibits lipopolysaccharide (LPS) stimulated TNF-alpha release in human PBMC and in human whole blood with IC50 values of 13 nM and 25 nM, respectively. Synonyms: 2-(2,6-dioxopiperidin-3-yl)-4-nitroisoindoline-1,3-dione; 4-Nitrothalidomide; 3-Nitrothalidomide; 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-nitro-; 2-(2,6-dioxopiperidin-3-yl)-4-nitroisoindole-1,3-dione; Phthalimide, N-(2,6-dioxo-3-piperidyl)-3-nitro-; OH13HKS17A; CHEMBL370441; C13H9N3O6; MFCD01748356; 2-(2,6-Dioxo-3-piperidinyl)-4-nitro-1H-isoindole-1,3(2H)-dione; 2-(2,6-dioxopiperidin-3-yl)-4-nitro-1H-isoindole-1,3(2H)-dione; N-(2,6-Dioxo-3-piperidyl)-3-nitrophthalimide; Nitrothalidomide; 3-(1',3'-Dioxo-4'-nitroisoindolinyl-2')-2,6-dioxopiperidine. Grades: > 95%. CAS No. 19171-18-7. Molecular formula: C13H9N3O6. Mole weight: 303.23. | |
| Pomalidomide Impurity 6 | An impurity of Pomalidomide which a derivative of thalidomide with antineoplastic effect. Grades: > 95%. Molecular formula: C21H14N4O6. Mole weight: 418.37. | |
| Pomalidomide Impurity 7 | An impurity of Pomalidomide which is a second generation immunomodulator and antineoplastic agent. Synonyms: Hydrolyzed Pomalidomide M10; 4-Amino-γ-(aminocarbonyl)-1,3-dihydro-1,3-dioxo-2H-isoindole-2-butanoic Acid. Grades: > 95%. CAS No. 918314-45-1. Molecular formula: C13H13N3O5. Mole weight: 291.27. | |
| Pomalidomide Impurity 8 | Pomalidomide Impurity 8 is an impurity of pomalidomide, which is a thalidomide derivative, a potent inhibitor of TNF-α production. It is an antiinflammatory and antitumor agent used in the treatment of multiple myeloma. Synonyms: CC-8017; CC 8017; CC8017; 2-(4-amino-1,3-dioxoisoindolin-2-yl)-4-carbamoylbutanoic acid. Grades: >98%. CAS No. 2635-64-5. Molecular formula: C13H13N3O5. Mole weight: 291.26. | |
| Pomalidomide Impurity 9 | An impurity of Pomalidomide which a derivative of thalidomide with antineoplastic effect. Grades: > 95%. Molecular formula: C10H18N2O5. Mole weight: 246.27. | |
| Pomalidomide-PEG1-C2-NH2 | Pomalidomide-PEG1-C2-NH2 is a crosslinker-E3 ligase ligand conjugate consisting of an E3 ligase ligand pomalidomide and a PEGylated crosslinker with terminal amine for reactivity with a carboxyl group on the target ligand. It has been used as a degrader building block in PROTAC for targeted protein degradation. Synonyms: Thalidomide-NH-PEG1-NH2; 4-((2-(2-aminoethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione; 4-{[2-(2-Aminoethoxy)ethyl]amino}-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione; 1H-Isoindole-1,3(2H)-dione, 4-[[2-(2-aminoethoxy)ethyl]amino]-2-(2,6-dioxo-3-piperidinyl)-. Grades: ≥95%. CAS No. 2138439-12-8. Molecular formula: C17H20N4O5. Mole weight: 360.36. | |
| Pomalidomide-PEG2-azide | Pomalidomide-PEG2-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology [1]. Pomalidomide-PEG2-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 2267306-14-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-137537. | |
| Pomalidomide-PEG2-C2-NH2 | Pomalidomide-PEG2-C2-NH2 is a crosslinker-E3 ligase ligand conjugate consisting of an E3 ligase ligand pomalidomide and a PEGylated crosslinker with terminal amine for reactivity with a carboxyl group on the target ligand. It has been used as a degrader building block in PROTAC for targeted protein degradation. Synonyms: Thalidomide-NH-PEG2-NH2; 4-((2-(2-(2-aminoethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione; 4-({2-[2-(2-Aminoethoxy)ethoxy]ethyl}amino)-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione; 1H-Isoindole-1,3(2H)-dione, 4-[[2-[2-(2-aminoethoxy)ethoxy]ethyl]amino]-2-(2,6-dioxo-3-piperidinyl)-; 4-({2-[2-(2-aminoethoxy)ethoxy]ethyl}amino)-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione; Thalidomide-NH-PEG2-C2-NH2. Grades: ≥95%. CAS No. 2093416-32-9. Molecular formula: C19H24N4O6. Mole weight: 404.42. | |
| Pomalidomide-PEG3-azide | Pomalidomide-PEG3-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology [1]. Pomalidomide-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 2267306-15-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-137538. | |
| Pomalidomide-PEG3-C2-NH2 hydrochloride | Pomalidomide-PEG3-C2-NH2 hydrochloride is a synthetic E3 ligase ligand-linker conjugate containing a cereblon ligand based on Pomalidomide and a PEG linker of 3 O(CH2)2 units with terminal amine, as a part of a variety of functionalized PROTAC molecules for binding to a target protein ligand. Synonyms: Cereblon Ligand-Linker Conjugates 5 hydrochloride; E3 ligase Ligand-Linker Conjugates 30 hydrochloride. CAS No. 2446474-09-3. Molecular formula: C21H29ClN4O7. Mole weight: 484.93. | |
| Pomalidomide-PEG3-C2-NH2 TFA | Pomalidomide-PEG3-C2-NH2 TFA (Cereblon Ligand-Linker Conjugates 5 (TFA)) is a synthetic E3 ligase ligand-linker conjugate comprising a Pomalidomide (HY-10984)-based cereblon ligand and a 3-unit PEG linker. Pomalidomide-PEG3-C2-NH2 TFA can be used for the synthesis of PROTACs [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Cereblon Ligand-Linker Conjugates 5 TFA; E3 ligase Ligand-Linker Conjugates 30 TFA. CAS No. 2414913-97-4. Pack Sizes: 50 mg; 100 mg; 500 mg; 1 g; 2 g. Product ID: HY-128716A. | |
| Pomalidomide-PEG4-azide | Pomalidomide-PEG4-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology [1]. Pomalidomide-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 2271036-47-4. Pack Sizes: 50 mg; 100 mg; 250 mg. Product ID: HY-141015. | |
| Pomalidomide-PEG4-C2-NH2 hydrochloride | Pomalidomide-PEG4-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker used in the synthesis of PROTACs. Uses: Scientific research. Group: Signaling pathways. CAS No. 2357105-92-9. Pack Sizes: 50 mg; 100 mg; 500 mg. Product ID: HY-112599B. | |
| Pomalidomide-PEG5-CO2H | Pomalidomide-PEG5-CO2H is a crosslinker-E3 ligase ligand conjugate consisting of an E3 ligase ligand pomalidomide and a PEGylated crosslinker with terminal carboxylic acid for reactivity with an amine on the target ligand. It has been used as a degrader building block in PROTAC for targeted protein degradation. Synonyms: 1-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-3,6,9,12,15-pentaoxaoctadecan-18-oic acid. Grades: ≥98%. CAS No. 2139348-63-1. Molecular formula: C26H35N3O11. Mole weight: 565.57. | |
| Pomegranate Extract | Pomegranate extract is prepared from the peel and seeds of the pomegranate the family Punicaceae which includes only one genus and two species. Pomegranate peel extract contains punicalagins, ellagic acid and pomegranate polyphenols, pomegranate extract offers abundant benefits for the cardiovascular system by preventing damage to arterial walls, promoting healthy blood pressure levels, improving blood flow to the heart, and preventing or reversing atherosclerosis. Group: Others. Mole weight: 1084.72. Pomegranate Extract; Punica granatum Linn. Cat No: EXTC-012. |  |
| Pomegranate Extract | Extract obtained from Punica Granatum (Pomegranate) fruits. Contains 20% extract dissolved in water and glycerin. Has toning, firming and skin-conditioning properties. Uses: Creams, tonics, hair car products and cleansers. Group: Skin actives. CAS No. 7732-18-5 / 56-81-5 / 84961-57-9 / 122-99-6. Appearance: Pink-amber to dark reddish amber liquid, characteristic odor. Catalog: CI-SC-0881. | |
| Pomegranate Powder | Pomegranate powder is made from fruit of fresh Pomegranate (punica granatum), Pomegranate juice powder contains Ellagic acid, polyphenols, glycosides, with effect of anti-cancer and anti-oxidant. Besides pomegranate powder also have many kinds of untrients with good water-solublility, widely used in foods and beverages. Group: Others. Pomegranate Powder; Punica granatum L. Cat No: EXTC-095. | |
| Pomegranate Powder- Indian material | Pomegranate Powder- Indian material. |  CA, FL & NJ |
| Pomiferin | Pomiferin (NSC 5113) acts as an potential inhibitor of HDAC , with an IC 50 of 1.05 μM, and also potently inhibits mTOR ( IC 50 , 6.2 μM). Uses: Scientific research. Group: Natural products. Alternative Names: NSC 5113. CAS No. 572-03-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N4315. | |
| Pomolic acid β-D-glucopyranosyl ester | Pomolic acid β-D-glucopyranosyl ester. Group: Biochemicals. CAS No. 83725-24-0. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| PON1 Activator (ZNPA, (Z)-2,3-bis (4-nitrophenyl)-acrylonitrile) | A cell-permeable stilbene derivative that serves as an aryl hydrocarbon receptor (AhR) and acts as a highly specific and potent inducer of paraoxonase 1 (PON1). Shown to be a better activator of PON1 mRNA (EC50=1uM) and inducer of PON1 enzymatic activity (>3-fold at 5um) when compared to resveratrol. However, it is devoid of any activity against estrogen receptors and is not shown to inhibit activity of tyrosine kinases. Also shown to antagonize the effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on cytochrome P4501A1 (CYP1A1). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Ponalrestat | Ponalrestat Inhibitor. Uses: Scientific use. Product Category: T2013. CAS No. 72702-95-5. |  |
| Ponalrestat | Ponalrestatis an aldose reductase inhibitor originator byAstraZeneca. It can block the conversion of glucose to sorbitol. Ponalrestatis shows selectivity for aldose reductase 2 over aldose reductase 1 with Ki values of 7.7 nM and 60 μM. Phase III for the treatment of diabetes was discontinued. Uses: Diabetes. Synonyms: Ponalrestat, ICI-128436; ICI 128436; ICI128436; MK-538; MK 538; MK538. Brand name: Statil; Statyl. QJ0339; QJ0339; QJ-0339; 2-(3-(4-bromo-2-fluorobenzyl)-4-oxo-3,4-dihydrophthalazin-1-yl)acetic acid. Grades: 98%. CAS No. 72702-95-5. Molecular formula: C17H12BrFN2O3. Mole weight: 391.20. | |
| Ponatinib | Ponatinib (AP24534) is an orally active multi-targeted kinase inhibitor with IC 50 s of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM, and 5.4 nM for Abl , PDGFRα , VEGFR2 , FGFR1 , and Src , respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AP24534. CAS No. 943319-70-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12047. | |
| Ponatinib | Ponatinib is a novel, potent multi-target inhibitor of Abl, PDGFRα, VEGFR2, FGFR1 and Src with IC50 of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM and 5.4 nM, respectively. Synonyms: 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide; AP24534; AP-24534; AP 24534; Ponatinib Brand name: Iclusig. Grades: >98%. CAS No. 943319-70-8. Molecular formula: C29H27F3N6O. Mole weight: 532.56. | |
| Ponatinib | Ponatinib / AP24534 is a novel, potent multi-target inhibitor of Abl, PDGFRα, VEGFR2, FGFR1 and Src with IC50 of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM and 5.4 nM in cell-free assays, respectively. Group: Fluorinated apis. Alternative Names: AP24534. CAS No. 943319-70-8. Molecular formula: C29H27F3N6O. Mole weight: 532.56. Appearance: White to off-white solid powder. Purity: >98%. IUPACName: 3- (2-imidazo[1, 2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[ (4-methylpiperazin-1-yl)methyl]-3- (trifluoromethyl)phenyl]benzamide. Catalog: OFC943319708. | |
| Ponatinib Active Metabolite A | Ponatinib Active Metabolite A. Uses: For analytical and research use. Group: Impurity standards. CAS No. 943319-87-7. Molecular Formula: C28H25F3N6O. Mole Weight: 518.54. Catalog: APB943319877. | |
| Ponatinib-D8 | Ponatinib-D8. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1562993-37-6. Molecular Formula: C29H19D8F3N6O. Mole Weight: 540.62. Catalog: APB1562993376. | |
| Ponatinib, Free Base (AP24534) | Ponatinib is a novel potent, orally available small molecule multitargeted kinase inhibitor. Ponatinib inhibits both native and mutant BCR-ABL. Ponatinib is used in the treatment of chronic myeloid leukemia (CML) with BCR-ABL kinase inhibitors. Ponatinib is the active ingredient in the drug product sold under the trade name Iclusig®, currently approved in at least one country for use in patients with chronic myeloid leukemia (CML) and Philadelphia chromosome positive (Ph+) acute lymphoblastic leukemia. Group: Biochemicals. Alternative Names: 3- (2-Imidazo[1, 2-b]pyridazin-3-ylethynyl) -4-methyl-N-[4-[ (4-methyl-1-piperazinyl) methyl]-3- (trifluoromethyl) phenyl]benzamide; AP 24534; Iclusig. Grades: Highly Purified. CAS No. 943319-70-8. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C29H27F3N6O, Molecular Weight: 532.56. US Biological Life Sciences. | Worldwide |
| Ponatinib hydrochloride | Ponatinib hydrochloride (AP24534 hydrochloride) is a hydrochloride of ponatinib. Ponatinib is an orally active multi-targeted kinase inhibitor with IC 50 s of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM, and 5.4 nM for Abl , PDGFRα , VEGFR2 , FGFR1 , and Src , respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AP24534 hydrochloride. CAS No. 1114544-31-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108766. | |
| Ponatinib hydrochloride | Ponatinib hydrochloride is an oral drug for the treatment of chronic myeloid leukemia (CML) and Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL). It is a multi-targeted tyrosine-kinase inhibitor. It has potential antiangiogenic and antineoplastic activities. It inhibits unmutated and all mutated forms of Bcr-Abl, including T315I, the highly drug therapy-resistant missense mutation of Bcr-Abl. It inhibits the tyrosine kinase receptor TIE2 and FMS-related tyrosine kinase receptor-3 (Flt3). It was developed by Ariad Pharm and has been listed. Uses: Ponatinib hydrochloride is an oral drug for the treatment of chronic myeloid leukemia (cml) and philadelphia chromosome-positive (ph+) acute lymphoblastic leukemia (all). it has potential antiangiogenic and antineoplastic activities. Synonyms: 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide hydrochloride; AP24534; AP-24534; AP 24534; Ponatinib HCl; Ponatinib hydrochloride trade name Iclusig. Grades: >98%. CAS No. 1114544-31-8. Molecular formula: C29H28ClF3N6O. Mole weight: 569.03. | |
| Ponatinib Impurity 1 | Ponatinib Impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 943320-61-4. Molecular Formula: C8H5N3. Mole Weight: 143.15. Catalog: APB943320614. | |
| Ponatinib Impurity 11 | Ponatinib Impurity 11. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2097674-16-1. Molecular Formula: C46H46F6N6O2. Mole Weight: 828.9. Catalog: APB2097674161. | |
| Ponatinib Impurity 12 | Ponatinib Impurity 12. Uses: For analytical and research use. Group: Impurity standards. CAS No. 694499-22-4. Molecular Formula: C8H5BrF3NO2. Mole Weight: 284.03. Catalog: APB694499224. | |
| Ponatinib Impurity 13 | Ponatinib Impurity 13. Uses: For analytical and research use. Group: Impurity standards. CAS No. 65934-74-9. Molecular Formula: C8H8F3N. Mole Weight: 175.15. Catalog: APB65934749. | |
| Ponatinib Impurity 2 | Ponatinib Impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 18087-73-5. Molecular Formula: C6H4BrN3. Mole Weight: 198.02. Catalog: APB18087735. | |
| Ponatinib Impurity 2 | Ponatinib Impurity 2. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1-(dibromomethyl)-4-nitro-2-(trifluoromethyl)benzene. CAS No. 122947-77-7. Molecular Formula: C8H4Br2F3NO2. Mole Weight: 362.93. Catalog: APB122947777. | |
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