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| Product | Description | |
|---|---|---|
| Pyruvic aldehyde, Technical Grade, 35-45% Aqueous Solution | Pyruvaldehyde is used in the synthesis and cytotoxicity evaluation of N-terminal analogues of tubulysin-U an antimitotic compound. Also used in the synthesis of imidazoles as potent calcitonin gene-related CGRP antagonists. Group: Biochemicals. Grades: Purified. CAS No. 78-98-8. Pack Sizes: 100g, 250g, 500g, 1Kg, 2Kg. Molecular Formula: C?H?O?, Molecular Weight: 72.06. US Biological Life Sciences. |  Worldwide |
| Pyruvonitrile | Pyruvonitrile. CAS No: 631-57-2 |  Sarchem Laboratories New Jersey NJ |
| Pyrvinium | Pyrvinium. Group: Biochemicals. Alternative Names: 4-[(3-carboxylato-2-hydroxynaphthalen-1-yl)methyl]-3-hydroxynaphthalene-2-carboxylate. Grades: Highly Purified. CAS No. 7187-62-4. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C75H70N6O6. US Biological Life Sciences. | Worldwide |
| Pyrvinium pamoate | Pyrvinium pamoate, a nonabsorbed anthelmintic drug, is a potent androgen receptor inhibitor and a selective WNT pathway inhibitor. Pyrvinium pamoate is a potential drug candidate for the treatment of cryptosporidiosis in both immunocompetent and immunocompromised individuals. Uses: Anthelmintics. Synonyms: VPC-14337; VPC 14337; VPC14337; 6-(Dimethylamino)-2-[2-(2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl)ethenyl]-1-methyl-4,4'-methylenebis[3-hydroxy-2-naphthalenecarboxylate] (2:1)-quinolinium; Alnoxin; Altolat; NSC 223622; PP; Pamovin; Vermitibier; Vipyrvinium embonate. CAS No. 3546-41-6. Molecular formula: C26H28N3.1/2C23H14O6. Mole weight: 575.7. |  |
| Pyrvinium Pamoate | Pyrvinium Pamoate is a potent noncompetitive inhibitor of the androgen receptor, with the application towards prostate cancer treatment. Antihelmintic. Group: Biochemicals. Alternative Names: Bis[6-(dimethylamino)-2-[2-(2,5-dimethyl-1-phenylpyrrol-3-yl)vinyl]-1-methylquinolinium] 4,4Â-Methylenebis[3-hydroxy-2-naphthoate]]; 6-(Dimethylamino)-2-[2-(2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl)ethenyl]-1-methyl-Quinolinium, Salt with 4,4Â-Methylenebis[3-hydroxy-2-naphthalenecarboxylic Acid] (2:1); 6-(dimM6thylamino)-2-[2-(2,5-dimethyl-1-phenylpyrrol-3-yl)vinyl]-1-methyl-Quinoliniussalt with 4,4Â-Methylenebis[3-hydroxy-2-naphthoic Acid] (2:1); bis[6-(Dimethylamino)-2-[2-(2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl)ethenyl]-1-methylquinolinium] 4,4Â-Methylenebis[3-hydroxy-2-naphthalenecarboxylic Acid on(2-); Bis[6-(dimethylamino)-2-[2-(2,5-dimethyl-1-phenylpyrrol-3-yl)vinyl]-1-methylquinolinium] 4,4Â-Methylenebis[3-hydroxy-2-naphthoic Acid ion(2-); 6-Dimethylamino-2-[2-(2,5-dimethyl-1-p. CAS No. 3546-41-6. Pack Sizes: 500mg. Molecular Formula: C23H14O6 2[C26H28N3], Molecular Weight: 1151.39. US Biological Life Sciences. | Worldwide |
| Pyxinol | Pyxinol is the main metabolite of 20S-protopanaxadiol in the human liver. Synonyms: Pixinol; Dammarane-3β,12β,25-triol, 20,24-epoxy-, (20R,24S)- (8CI); (3β,12β,20R,24S)-20,24-Epoxydammarane-3,12,25-triol. CAS No. 25330-18-1. Molecular formula: C30H52O4. Mole weight: 476.73. | |
| PYZD 4409 | PYZD 4409. Group: Biochemicals. Grades: Purified. CAS No. 423148-78-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| PYZD-4409 | PYZD-4409 is an inhibitor of ubiquitin-activating enzyme UBA1 (E1). PYZD-4409 induced cell death in malignant cells and preferentially inhibited the clonogenic growth of primary acute myeloid leukemia cells compared with normal hematopoietic cells. Mechanistically, genetic or chemical inhibition of E1 increased expression of E1 stress markers. Moreover, BI-1 overexpression blocked cell death after E1 inhibition, suggesting ER stress is functionally important for cell death after E1 inhibition. Finally, in a mouse model of leukemia, intraperitoneal administration of PYZD-4409 decreased tumor weight and volume compared with control without untoward toxicity. Thus, our work highlights the E1 enzyme as a novel target for the treatment of hematologic malignancies. Synonyms: PYZD-4409; PYZD 4409; PYZD4409. Grades: 0.98. CAS No. 423148-78-1. Molecular formula: C14H7ClFN3O5. Mole weight: 351.674. | |
| Pz-1 | Pz-1 is a cell-permeable, non-cytotoxic (up to 0.1 μM and 6 days; NIH/3T3 cells), and highly potent RET and VEGFR2 inhibitor with IC50s of less than 1 nM for both wild type kinases. Synonyms: N-(5-(Tert-Butyl)isoxazol-3-yl)-2-(4-(5-(1-methyl-1H-pyrazol-4-yl)-1H-benzo[d]imidazol-1-yl)phenyl)acetamide. CAS No. 1800505-64-9. Molecular formula: C26H26N6O2. Mole weight: 454.52. | |
| PZ-II-029 | PZ-II-029,a pyrazoloquinolinone, was reported as the first postitive modulator of GABAA α6β3γ2 subtype functionally selective ligands to date. Synonyms: 3H-Pyrazolo[4,3-c]quinolin-3-one, 2,5-dihydro-7-methoxy-2-(4-methoxyphenyl)-; 2,5-Dihydro-7-methoxy-2-(4-methoxyphenyl)-3H-pyrazolo[4,3-c]quinolin-3-one; PZII-029; PZ II-029; PZ-II029; PZII029; PZ II029; PZII 029. Grades: ≥98% by HPLC. CAS No. 164025-44-9. Molecular formula: C18H15N3O3. Mole weight: 321.33. | |
| PZM-21 | PZM-21 is a potent and selective μ opioid receptor agonist with an EC50 of 1.8 nM. PZM21 is an experimental opioid analgesic that is being studied for the treatment of pain. Synonyms: PZM21. Grades: ≥95%. CAS No. 1997387-43-5. Molecular formula: C19H27N3O2S. Mole weight: 361.5. | |
| PZ-Peptide | PZ-Peptide is a chromogenic substrate for the assay of collagenase and thimet oligopeptidase (Pz-peptidase, metalloendopeptidase 24.15, collagenase-like peptidase). Synonyms: 4-Phenylazobenzyloxycarbonyl-L-pro-leu-gly-pro-D-arg dihydrate; Pz-Cpz-Pro-Leu-Gly-Pro-Arg. CAS No. 17011-78-8. Molecular formula: C38H52N10O8. Mole weight: 776.88. | |
