A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Phytochelatin 3 (PC 3) is the small metal chelating peptide that can be used for chelating heavy metals [1]. Uses: Scientific research. Group: Peptides. Alternative Names: PC 3. CAS No. 86220-45-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P3320.
Phytochelatin 5
Phytochelatin 5 is metal-binding compound produced by plants. Phytochelatin 5 may reduce bioavailability of dietary toxic metals such as cadmium [1]. Uses: Scientific research. Group: Peptides. Alternative Names: PC 5. CAS No. 99465-97-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P3322.
phytochromobilin:ferredoxin oxidoreductase
Catalyses the two-electron reduction of biliverdin IX&alpha. Can use [2Fe-2S] ferredoxins from a number of sources as acceptor but not the [4Fe-4S] ferredoxin from Clostridium pasteurianum. The isomerization of (3Z)-phytochromobilin to (3E)-phytochromobilin is thought to occur prior to covalent attachment to apophytochrome in the plant cell cytoplasm. Flavodoxins can be used instead of ferredoxin. Group: Enzymes. Synonyms: HY2; PPhi B synthase; phytochromobilin synthase. Enzyme Commission Number: EC 1.3.7.4. CAS No. 138263-99-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1399; phytochromobilin:ferredoxin oxidoreductase; EC 1.3.7.4; 138263-99-7; HY2; PPhi B synthase; phytochromobilin synthase. Cat No: EXWM-1399.
This enzyme is involved in carotenoid biosynthesis and catalyses up to five desaturation steps (cf. EC 1.3.99.28 [phytoene desaturase (neurosporene-forming)], EC 1.3.99.29 [phytoene desaturase (ζ-carotene-forming)] and EC 1.3.99.31 [phytoene desaturase (lycopene-forming)]). Group: Enzymes. Synonyms: 5-step phytoene desaturase; five-step phytoene desaturase; phytoene desaturase (ambiguous); Al-1. Enzyme Commission Number: EC 1.3.99.30. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1432; phytoene desaturase (3,4-didehydrolycopene-forming); EC 1.3.99.30; 5-step phytoene desaturase; five-step phytoene desaturase; phytoene desaturase (ambiguous); Al-1. Cat No: EXWM-1432.
phytoene desaturase (lycopene-forming)
Requires FAD. The enzyme is involved in carotenoid biosynthesis and catalyses up to four desaturation steps (cf. EC 1.3.99.28 [phytoene desaturase (neurosporene-forming)], EC 1.3.99.29 [phytoene desaturase (ζ-carotene-forming)] and EC 1.3.99.30 [phytoene desaturase (3,4-didehydrolycopene-forming)]). Group: Enzymes. Synonyms: 4-step phytoene desaturase; four-step phytoene desaturase; phytoene desaturase (ambiguous); CrtI (ambiguous). Enzyme Commission Number: EC 1.3.99.31. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1433; phytoene desaturase (lycopene-forming); EC 1.3.99.31; 4-step phytoene desaturase; four-step phytoene desaturase; phytoene desaturase (ambiguous); CrtI (ambiguous). Cat No: EXWM-1433.
phytoene desaturase (neurosporene-forming)
This enzyme is involved in carotenoid biosynthesis and catalyses up to three desaturation steps (cf. EC 1.3.99.29 [phytoene desaturase (ζ-carotene-forming)], EC 1.3.99.30 [phytoene desaturase (3,4-didehydrolycopene-forming)], EC 1.3.99.31 [phytoene desaturase (lycopene-forming)]). The enzyme is activated by FAD. NAD+, NADP+ or ATP show no activating effect. Group: Enzymes. Synonyms: 3-step phytoene desaturase; three-step phytoene desaturase; phytoene desaturase (ambiguous); CrtI (ambiguous). Enzyme Commission Number: EC 1.3.99.28. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1430; phytoene desaturase (neurosporene-forming); EC 1.3.99.28; 3-step phytoene desaturase; three-step phytoene desaturase; phytoene desaturase (ambiguous); CrtI (ambiguous). Cat No: EXWM-1430.
phytoene desaturase (ζ-carotene-forming)
The enzyme is involved in carotenoid biosynthesis and catalyses up to two desaturation steps (cf. EC 1.3.99.28 [phytoene desaturase (neurosporene-forming)], EC 1.3.99.30 [phytoene desaturase (3,4-didehydrolycopene-forming)] and EC 1.3.99.31 [phytoene desaturase (lycopene-forming)]). Group: Enzymes. Synonyms: CrtIa; 2-step phytoene desaturase (ambiguous); two-step phytoene desaturase (ambiguous). Enzyme Commission Number: EC 1.3.99.29. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1431; phytoene desaturase (ζ-carotene-forming); EC 1.3.99.29; CrtIa; 2-step phytoene desaturase (ambiguous); two-step phytoene desaturase (ambiguous). Cat No: EXWM-1431.
Phytohemagglutinin
Phytohemagglutinin (PHA-M), the major seed lectin of the common bean, Phaseolus vulgaris, accumulates in the parenchyma cells of the cotyledons. Phytohemagglutinin is a T-cell activator. Stimulation of human mononuclear leukocytes by Phytohemagglutinin induces the expression of ChAT mRNA, and potentiated ACh synthesis [1]. Uses: Scientific research. Group: Natural products. Alternative Names: PHA-M. CAS No. 9008-97-3. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N7038.
Phytohemagglutinin P
Phytohemagglutinin P (PHA-P) is a mitogen known to selectively stimulate cells of hematogenous or lymphoid monocytic origin[1]. Uses: Scientific research. Group: Natural products. Alternative Names: PHA-P. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N7038A.
phytol
phytol. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (7R,11R,E)-3,7,11,15-tetramethylhexadec-2-en-1-ol. CAS No. 150-86-7. Molecular formula: C20H40O. Mole weight: 296.31. Catalog: APB150867.
Phytol
Phytol ((E)-Phytol) is an orally active diterpenoid alcohol that can be extracted from chlorophyll. Phytol has antioxidant, anti-inflammatory, anti-schistosomiasis and antibacterial activities [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: (E)?-Phytol. CAS No. 150-86-7. Pack Sizes: 10 mM * 1 mL; 1 g. Product ID: HY-N3075.
Phytol
Phytol. Group: Biochemicals. CAS No. 150-86-7. Pack Sizes: 100ul. US Biological Life Sciences.
Worldwide
Phytolaccagenin
Phytolaccagenin. Group: Biochemicals. Grades: Plant Grade. CAS No. 1802-12-6. Pack Sizes: 10mg. Molecular Formula: C31H48O7, Molecular Weight: 532.71. US Biological Life Sciences.
Worldwide
Phytol (cis/trans mixture)
Phytol is a reagent that is used in the preparation of α-tocopherol analogs as mitochondrial antioxidants. Group: Biochemicals. Alternative Names: 3,7,11,15-Tetramethyl-2-hexadecen-1-ol; 3,7,11,15-Tetramethylhexadec-2-en-1-ol. Grades: Highly Purified. CAS No. 7541-49-3. Pack Sizes: 1g, 2.5g, 5g. Molecular Formula: C??H??O, Molecular Weight: 296.53. US Biological Life Sciences.
Worldwide
phytol kinase
The enzyme is found in plants and photosynthetic algae and is involved in phytol salvage. It can use UTP as an alternative phosphate donor with lower activity. Group: Enzymes. Synonyms: VTE5 (gene name). Enzyme Commission Number: EC 2.7.1.182. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3014; phytol kinase; EC 2.7.1.182; VTE5 (gene name). Cat No: EXWM-3014.
Phytol (Natural isomer). Group: Biochemicals. Alternative Names: 3,7,11,15-Tetramethyl-2-hexadecen-1-ol. Grades: Highly Purified. CAS No. 7541-49-3. Pack Sizes: 25g, 50g, 100g. Molecular Formula: C20H40O, Molecular Weight: 296.53. US Biological Life Sciences.
Worldwide
Phytol (Natural isomer) 97+% (GC)
Phytol (Natural isomer) 97+% (GC). Group: Biochemicals. Alternative Names: 3,7,11,15-Tetramethyl-2-hexadecen-1-ol. Grades: GC. CAS No. 7541-49-3. Pack Sizes: 1g, 5g, 25g, 100g, 250g. Molecular Formula: C20H40O, Molecular Weight: 296.53. US Biological Life Sciences.
Worldwide
Phytonadione
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Phytonadione 1% (Vitamin K1)
Phytonadione 1% (Vitamin K1).
CA, FL & NJ
Phytonadione USP (Vitamin K1)
Phytonadione USP (Vitamin K1).
CA, FL & NJ
Phytone
Hexahydrofarnesyl acetone is a fragnance agent commonly used in jasmine compositions. Synonyms: 6,10,14-trimethyl-2-pentadecanone; 6,10,14-trimethylpentadecan-2-one. Grade: > 98 %. CAS No. 502-69-2. Molecular formula: C18H36O. Mole weight: 268.48.
Phytopin Powder
Phytopin Powder (15 kg Fibers). CAS No. MIXTURE. Kosher: Y. VIGON Item # 504876. Categories: Speciality Ingrdients Suppliers.
America & Internationally
Phytosphingosine
Phytosphingosine is a phospholipid with anti-inflammatory, antibacterial, and anti-cancer activities, which can induce apoptosis. Phytosphingosine is an immune regulator and can be used in the study of inflammatory skin diseases. Phytosphingosine is also an activator of GPR120 with an IC 50 value of 33.4 μM and can be used in the study of type II diabetes [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: 4-Hydroxysphinganine. CAS No. 554-62-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W011303.
Phytosterols
1. Protecting the bladder smooth muscle against cellular damage caused by ischemia and reperfusion. 2. Inhibiting benign prostatic hypertrophy and cancer of the prostate. Restoring secretory activity of prostate epithelium. 3. Clearing bladder neck urethral obstruction, significantly improving urologic symptoms and flow measures. 4. Also used for incontinence, urine retention, polyuria or frequent urination, dysuria. Uses: Designed for use in research and industrial production. Product Category: Material of health food. Appearance: White powder. CAS No. 83-46-5. Molecular formula: C29H50O. Mole weight: 414.71. Product ID: ACM83465. Alfa Chemistry ISO 9001:2015 Certified.
PI-083 is a platelet aggregation inhibitor produced by Streptomyces matensis A-6621. It is active against gram-positive bacteria with MIC of 0.39-3.13 μg/mL. It inhibits platelet aggregation induced by ADP, Arachidonic Acid and collagen with MIC of 30.4, 1.9 and 3.8 μmol/L. It also inhibits KB cell growth with IC50 of 0.026 μmol/L. Synonyms: PI 083; PI083. CAS No. 119341-57-0. Molecular formula: C43H50O16. Mole weight: 822.8.
PI-103
PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of phosphatidylinositol 3-kinase (PI3K) family members with selectivity toward DNA-PK, PI3K (p110α), and mTOR. Uses: Designed for use in research and industrial production. Additional or Alternative Names: PI103; PI-103; PI 103. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 371935-74-9. Molecular formula: C19H17ClN4O3. Mole weight: 384.82. Purity: >98%. IUPACName: 3-(4-morpholinopyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl)phenol. Canonical SMILES: OC1=CC=CC(C2=NC(N3CCOCC3)=C(OC4=NC=CC=C45)C5=N2)=C1. Product ID: ACM371935749. Alfa Chemistry ISO 9001:2015 Certified. Categories: PS-100 Karachi East-IV.
PI-103
PI-103 is a potent PI3K and mTOR inhibitor with IC50s of 8 nM, 88 nM, 48 nM, 150 nM, 20 nM, and 83 nM for p110?, p110?, p110?, p110?, mTORC1, and mTORC2. PI-103 also inhibits DNA-PK with an IC50 of 2 nM. PI-103 induces autophagy[1][2][3][4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 371935-74-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10115.
A cell-permeable, ATP-competitive inhibitor of phosphatidylinositol 3-kinase (PI3K) family members with selectivity toward DNA-PK, PI3K (p110α), and mTOR. The IC50 values are 2, 8, 20, 26, 48, 83, 88, 150 nM for DNA-PK, p110α, mTORC1, PI3-KC2 β, p110δ, mTORC2, p110 β, and p110γ, respectively. Inhibits growth of human tumor xenografts in mice in vivo. Group: Biochemicals. Alternative Names: 3-(4-(4-Morpholinyl)pyrido[3, 2:4, 5]furo[3, 2-d]pyrimidin-2-yl)phenol. Grades: Highly Purified. CAS No. 371935-74-9. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
PI-103 - CAS 371935-74-9
A cell-permeable pyridinylfuranopyrimidine compound that acts as a potent and ATP-competitive inhibitor of DNA-PK, PI3-K, and mTOR. Group: Fluorescence/luminescence spectroscopy.
PI 103 hydrochloride
PI 103 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 371935-79-4. Pack Sizes: 1mg, 10mg, 50mg. US Biological Life Sciences.
Worldwide
PI-103 Hydrochloride
PI-103 Hydrochloride is a dual PI3K and mTOR inhibitor with IC50s of 8 nM, 88 nM, 48 nM, 150 nM, 20 nM, and 83 nM for p110?, p110?, p110?, p110?, mTORC1, and mTORC2. PI-103 Hydrochloride also inhibits DNA-PK with an IC50 of 2 nM. PI-103 Hydrochloride induces autophagy[1][2][3][4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 371935-79-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10115A.
PI-1840
PI-1840 is a potent and selective chymotrypsin-like (CT-L) inhibitor for with an IC50 value of 27 nM. PI-1840 inhibits cell proliferation and arrest cell cycle at G2/M phase. PI-1840 induces apoptosis and induces autophagy. PI-1840 induces the accumulation of proteasome substrates p27, Bax, and I?B-?[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1401223-22-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12286.
PI-200
PI-200 is a platelet aggregation inhibitor produced by Streptomyces sp. A7498. It inhibited ADP-induced aggregation of rabbit platelets with IC50 of 3.8 x 10(-4) M. Synonyms: PI 200; PI200. CAS No. 143605-57-6. Molecular formula: C17H26O2. Mole weight: 262.4.
PI-201
PI-201 is a platelet aggregation inhibitor produced by Streptomyces sp. A7498. It inhibited ADP-induced aggregation of rabbit platelets with IC50 of 7.1 x 10(-4) M. Synonyms: PI 201; PI201. CAS No. 143605-56-5. Molecular formula: C17H28O3. Mole weight: 280.4.
PI230
PI230 is an antimicrobial peptide found in Pisum sativum (Garden pea), and has antimicrobial activity. Synonyms: Defensin-like protein 230. Grade: >98%.
PI-273
PI-273 is a first reversibly and specific phosphatidylinositol 4-kinase (PI4KII?) inhibitor with an IC50 of 0.47 ?M. PI-273 can inhibit breast cancer cell proliferation, block the cell cycle and induce cell apoptosis[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 925069-34-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103489.
The PI 3,4-K inhibitor, PIK-93, also referenced under CAS 593960-11-3, controls the biological activity of PI 3,4-K. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
A cell-permeable phenylthiazole compound that acts as a potent, reversible and ATP-competitive PI 3,4-K family selective inhibitor (IC50=16, 19, 39 and 64nM for p110y, PI 4-KIIb, p110a and DNA-PK, respectively). Moderately inhibits p110d, PI 3-KC2b, hsVPS34, ATM, p110b and PI 4-KIIIa (IC50=0.120, 0.140, 0.320, 0.490, 0.590 and 1.1uM, respectively) with minimal inhibition towards a panel of 36-kinases (IC50>10uM). Shown to block ceramide transfer protein-mediated ceramide traffic between endoplasmic reticulum and Golgi in transfected COS-7 cells at 250nM. Group: Biochemicals. Grades: Highly Purified. CAS No. 593960-11-3. Pack Sizes: 5mg. US Biological Life Sciences.
PI3K/AKT-IN-2 (Compound 12c) is a PI3K and AKT inhibitor. PI3K/AKT-IN-2 blocks the epithelial-mesenchymal transition (EMT) and induces apoptosis. PI3K/AKT-IN-2 inhibits the polymerization of tubulin [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2684412-41-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-147768.
PI3K-AKT-mTOR Compound Library
A unique collection of 425 compounds targeting PI3K/Akt/mTOR signaling for research in PI3K/Akt/mTOR signaling, and drug discovery in diseases involved with PI3K/Akt/mTOR signaling; - Effective tool for studying cell growth, proliferation, and apoptosis; - Targets include AKT, AMPK, mTOR, PI3K, ATR/ATM, etc; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L1300. Categories: PI3K-AKT-mTOR Compounds Libraries.
PI3Kδ/γ-IN-1
PI3Kδ/γ-IN-1 is a potent, selective PI3K-δ/γ inhibitor for research of hematological malignancies. Uses: Scientific research. Group: Signaling pathways. CAS No. 1980884-01-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144993.
PI3Kδ-IN-16
PI3Kδ-IN-16 is a potent and selective inhibitor of PI3K&delta. PI3Kδ-IN-16 has a strong anti-proliferative effect on cells, causing cell cycle arrest and inducing apoptosis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2766437-35-6. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-155232.
PI3K-IN-32
PI3K-IN-32 (compound 35) is a potent PI3K p110α inhibitor with an pIC 50 of 6.85 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 371934-59-7. Pack Sizes: 5 mg. Product ID: HY-103030.
PI3K-IN-46
PI3K-IN-46 (Intermediate 4) is an intermediate in the synthesis of PI3K inhibitor (2-imino-azolinone-vinyl fused-benzene derivative) that can be used for the research of autoimmune disorders, cardiovascular diseases, and neurodegenerative diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 304645-61-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-48869.
The PI 3-K? Inhibitor, also referenced under CAS 648450-29-7, controls the biological activity of PI 3-K?. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
PI 3-K? Inhibitor II - CAS 648449-76-7
The PI 3-K? Inhibitor II, also referenced under CAS 648449-76-7, controls the biological activity of PI 3-K?. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
PI 3-K? Inhibitor IV - CAS 1188890-32-5
The PI 3-K? Inhibitor IV, also referenced under CAS 1188890-32-5, controls the biological activity of PI 3-K?. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
PI 3-K inhibitor IX, PIK-90 - CAS 677338-12-4
The PI 3-K inhibitor IX, PIK-90, also referenced under CAS 677338-12-4, controls the biological activity of PI 3-K. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
PI3K? Inhibitor, SW30
The PI3K? Inhibitor, SW30 controls the biological activity of PI3K?. This small molecule/inhibitor is primarily used for Membrane applications. Group: Fluorescence/luminescence spectroscopy.
PI 3-K? Inhibitor VII - CAS 6318-41-8
The PI 3-K? Inhibitor VII, also referenced under CAS 6318-41-8, controls the biological activity of PI 3-K?. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
PI 3-K? Inhibitor VIII - CAS 372196-77-5
The PI 3-K? Inhibitor VIII controls the biological activity of PI 3-K?. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
PI 3-K? Inhibitor VI, TGX-221 - CAS 663619-89-4
The PI 3-K? Inhibitor VI, TGX-221, also referenced under CAS 663619-89-4, controls the biological activity of PI 3-K?. This small molecule/inhibitor is primarily used for Cell Signaling applications. Group: Fluorescence/luminescence spectroscopy.
PI 3-K? Inhibitor X, IC87114 - CAS 371242-69-2
The PI 3-K? Inhibitor X, IC87114, also referenced under CAS 371242-69-2, controls the biological activity of PI 3-K?. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
PI 3-K Inhibitor XI, HWT - CAS 58053-83-1
The PI 3-K Inhibitor XI, HWT, also referenced under CAS 58053-83-1, controls the biological activity of PI 3-K. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
PI 3-K Inhibitor XVIII (p110 beta-G beta gamma Interaction Inhibitor peptide, Cell-permeable, Myr-N-KAAEIASSDSANVSSRGGKKFL PV-NH2)
An N-myristoylated cell-permeable PI 3-K p110 beta-derived G beta-gamma-binding peptide (aa514-537 in p110 beta C2-helical linker region) that prevents G beta-gamma-, but not RTK-, mediated p100 beta activation both in cell-free assays (1uM) and in cultures (30uM in p110 beta/p85/Akt/G beta-gamma-transfected HEK 293E cells) without affecting basal p100 beta activity, p110 beta-Rab5 interaction, nor G beta-gamma-dependent activation of adenylyl cyclase or p101-p110-gamma dimer. The ATP-competitive p110 beta inhibitior TGX-221 can be used in conjunction for studying G beta-gamma dependency of p110 beta-mediated cellular functions. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
PI 3-K?/? Inhibitor XV, SW-14
The PI 3-K?/? Inhibitor XV, SW-14 controls the biological activity of PI 3-K?/?. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
PI 3-K/mTOR Inhibitor III, PKI-179 - CAS 1197160-28-3
The PI 3-K/mTOR Inhibitor III, PKI-179, also referenced under CAS 1197160-28-3, controls the biological activity of PI 3-K/mTOR. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.