A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Pilaralisib (XL147; SAR245408) is a potent and highly selective class I PI3K s inhibitor with IC 50 s of 39 nM, 383 nM, 23 nM and 36 nM for PI3Kα, PI3Kβ, PI3Kγ, and PI3K&delta. Uses: Scientific research. Group: Signaling pathways. Alternative Names: XL-147; SAR245408. CAS No. 934526-89-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16526.
Pilatin
It is produced by the strain of Flagelloscypha pilatii JK 322. Like Marasmic acid, it has inhibitory effects on bacteria and fungi, and has strong inhibitory effects on the incorporation of thymidin and ureidin into DNA and RNA in Ehrlich carcinoma ascites cells. It can cause frameshift mutations in Salmonella typhimuium TA98. Synonyms: 2-Hexenoic acid, 5a,7,8,8a-tetrahydro-3,5a-dihydroxy-7,7-dimethyl-4-formyl-1-oxo-3H,6H,3a,8b-methano-1H-indeno(4,5-c)furan-6-yl ester, (3S-(3-alpha,3a-beta,5a-beta,6-alpha(E),8a-beta,9b-beta))-; 2-Hexenoic acid, 5a,7,8,8a-tetrahydro-4-formyl-3,5a-dihydroxy-7,7-dimethyl-1-oxo-3H,6H-3a,8b-methano-1H-indeno(4,5-c)furan-6-yl ester, (3S-(3alpha,3abeta,5abeta,6alpha(E),8abeta,9bbeta))-. CAS No. 119525-97-2. Molecular formula: C21H26O7. Mole weight: 390.43.
Pillaromycin A
It is produced by the strain of Str. flavovirens 65786. It has anti-mycobacteria, gram-positive bacteria and gram-negative bacteria effects, but the effect of anti-gram-negative bacteria is weak. It also has antitumor activity similar to colchicine. Synonyms: 5(1H)-Naphthacenone, 2,4a,12,12a-tetrahydro-3-acetyl-4a-((tetrahyro-5-hydroxy-5(hydroxyacetyl)-6-methyl-2H-pyran-2-yl)oxy)-1,2,6,7-tetrahydroxy-, (1R-(1-alpha,2-alpha,4a-alpha(2S*,5S*,6S*),12a-alpha))-; 5(1H)-Naphthacenone,3-acetyl-2,4a,12,12a-tetrahydro-1,2,6,7-tetrahydroxy-4a-[[(2S,5S,6S)-tetrahydro-5-hydroxy-5-(hydroxyacetyl)-6-methyl-2H-pyran-2-yl]oxy]-, (1R,2S,4aR,12aR)-; NSC 102812. CAS No. 30361-37-6. Molecular formula: C28H30O11. Mole weight: 542.53.
Pilocarpic acid sodium salt
Pilocarpic acid sodium salt. Group: Biochemicals. Alternative Names: [S-(R*,S*)]-a-Ethyl-b-(hydroxymethyl)-1-methyl-1H-imidazole-5-butanoic acid monosodium salt; Sodium pilocarpate. Grades: Highly Purified. CAS No. 92598-79-3. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C11H17N2NaO3. US Biological Life Sciences.
Worldwide
Pilocarpic Acid Sodium Salt
Pilocarpic Acid Sodium Salt. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Sodium Pilocarpate. Appearance: Solid. CAS No. 92598-79-3. Molecular formula: C11H17N2NaO3. Mole weight: 248.25. Purity: 0.95. Product ID: ACM92598793. Alfa Chemistry ISO 9001:2015 Certified. Categories: Isopilocarpic Acid Sodium Salt.
Pilocarpine
Pilocarpine. Group: Biochemicals. Alternative Names: cis-3-Ethyl-4- (1-methyl-5-imidazolylmethyl) dihydro-2 (3H) -furanone. Grades: Highly Purified. CAS No. 92-13-7. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C11H16N2O2. US Biological Life Sciences.
Worldwide
Pilocarpine
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardspharma & vet compounds & metabolitespharma & vet compounds & metabolites. Alternative Names: Ocusert P 20, Pilocarpol, Ocusert Pilo, 2(3H)-Furanone, 3-ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-, (3S-cis)-, Pilocarpine, (+)-,2(3H)-Furanone, 3-ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-, (3S,4R)-, Spersacarpine, (3S,4R)-3-Ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-2(3H)-furanone, Ocucarpine, Pilocarpine (8CI), (+)-Pilocarpine, Syncarpine, Pilokarpin, Ocusert Pilo 40.
Pilocarpine
Pilocarpine is a selective M3-type muscarinic acetylcholine receptor ( M3 muscarinic receptor ) agonist. Uses: Scientific research. Group: Signaling pathways. CAS No. 92-13-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-B0726A.
Pilocarpine-[d3] hydrochloride
Pilocarpine-[d3] hydrochloride is a deuterated labelled form of Pilocarpine, which is used as a miotic in the treatment of glaucoma. Synonyms: Pilocarpine-d3 HCl; Pilocarpine-d3 hydrochloride; Pilocarpine-[d3] HCl. Grade: > 95%. Molecular formula: C11H13N2O2D3·HCl. Mole weight: 247.74.
Pilocarpine-d3- hydrochloride
Pilocarpine-d3- hydrochloride
Sarchem Laboratories New Jersey NJ
Pilocarpine Hydrochloride
Pilocarpine Hydrochloride is a potent M3-type muscarinic acetylcholine receptor ( M3 muscarinic receptor ) agonist. Uses: Scientific research. Group: Natural products. CAS No. 54-71-7. Pack Sizes: 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B0726.
Pilocarpine nitrate
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
It is produced by the strain of Str. pilosus. It's a phenanthrene compound. It has inhibitory effect on mycobacterium and protozoa, but the effect is not strong. Synonyms: 9,10-Phenanthrenedione, 1,8-dihydroxy-2-methyl-3-(4-methyl-1-oxopentyl)-; 1,8-Dihydroxy-2-methyl-3-(4-methylpentanoyl)-9,10-phenanthrenedione. CAS No. 25414-26-0. Molecular formula: C21H20O5. Mole weight: 352.38.
Pilose Asiabell Root Extract
Pilose Asiabell Root Extract. Applications: Used for health care products, dietary supplements, herb medecine as nourishing tonic. Group: Others. Synonyms: Pilose Asiabell Root Extract; Radix Codonopsis L. Purity: 10:1 by TLC. Appearance: Brown-yellow fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Rhizoma. Species: Radix Codonopsis L. Pilose Asiabell Root Extract; Radix Codonopsis L.; plant extract. Pack: 25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-143.
Pilosulin 1
Pilosulin 1 is an antimicrobial peptide found in venom of Myrmecia pilosula (Jack jumper ant). It has anti-gram-positive bacteria, gram-negative bacteria, Fungi and Mammalian cells activity. Grade: ≥96%.
Pilosulin 2
Pilosulin 2 is an antimicrobial peptide found in Myrmecia pilosula (venom, Australia), and has antimicrobial activity. Synonyms: H-Ile-Asp-Trp-Lys-Lys-Val-Asp-Trp-Lys-Lys-Val-Ser-Lys-Lys-Thr-Cys-Lys-Val-Met-Leu-Lys-Ala-Cys-Lys-Phe-Leu-Gly-OH (Disulfide bridge: Cys16-Cys23). Grade: ≥97%. Molecular formula: C149H246N38O34S3. Mole weight: 3210.02.
Pilosulin 3
Pilosulin 3 is an antimicrobial peptide found in Myrmecia banksi (venom, Australia), and has antibacterial activity against gram-negative bacteria Escherichia coli (MIC<25 μM) and gram-positive bacteria Staphylococcus aureus (MIC<25 μM), Bacillus subtilis (MIC<50 μM). Synonyms: H-Ile-Ile-Gly-Leu-Val-Ser-Lys-Gly-Thr-Cys-Val-Leu-Val-Lys-Thr-Val-Cys-Lys-Lys-Val-Leu-Lys-Gln-Gly-OH (Disulfide bridge: Cys10-Cys17). Grade: ≥97%. Molecular formula: C113H206N30O29S2. Mole weight: 2513.19.
Pilosulin 4
Pilosulin 4 is an antimicrobial peptide found in Myrmecia banksi (Jack jumper ant), and has antibacterial activity against gram-negative bacteria Escherichia coli (MIC<6.25 μM), Pseudomonas aeruginosa (MIC<25 μM) and gram-positive bacteria Staphylococcus aureus (MIC<6.25 μM), Bacillus subtilis (MIC<50 μM). Synonyms: H-Phe-Asp-Ile-Thr-Lys-Leu-Asn-Ile-Lys-Lys-Leu-Thr-Lys-Ala-Thr-Cys-Lys-Val-Ile-Ser-Lys-Gly-Ala-Ser-Met-Cys-Lys-Val-Leu-Phe-Asp-Lys-Lys-Lys-Gln-Glu-OH (Disulfide bridge: Cys16-Cys26). Grade: ≥97%. Molecular formula: C183H316N48O50S3. Mole weight: 4085.01.
Pilosulin 5
Pilosulin 5 is an antimicrobial peptide found in Myrmecia pilosula (Jack jumper ant, venom, Australia), and has antimicrobial activity. Synonyms: Asp-Val-Lys-Gly-Met-Lys-Lys-Ala-Ile-Lys-Gly-Ile-Leu-Asp-Cys-Val-Ile-Glu-Lys-Gly-Tyr-Asp-Lys-Leu-Ala-Ala-Lys-Leu-Lys-Lys-Val-Ile-Gln-Gln-Leu-Trp-Glu. Grade: ≥95%. Molecular formula: C192H327N49O51S2. Mole weight: 4202.14.
Pim1/AKK1-IN-1 is a potent multi-kinase inhibitor with Kd values of 35 nM/53 nM/75 nM/380 nM for Pim1/AKK1/MST2/LKB1 respectively, and also inhibits MPSK1 and TNIK. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LKB1/AAK1 dual inhibitor. CAS No. 1093222-27-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-10371.
PIM1-IN-1
PIM1-IN-1 is a potent and highly selective PIM1/3 inhibitor, with IC 50 s of 7, 5530 and 70 nM for PIM1, PIM2, and PIM3, respectively, inhibits the phosphorylation of BAD, a downstream target of PIM, with an EC 50 of 262 nM. PIM1-IN-1 shows no obvious effect on FLT3 or hERG binding. Antiproliferative and anti-cancer activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1417630-95-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111552.
PIM-1 Inhibitor 2
PIM-1 Inhibitor 2. Group: Biochemicals. Grades: Purified. CAS No. 477845-12-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
A cell-permeable hydroxyphenyl-propylidene-benzohydrazide compound that acts as a potent, ATP-competitive (Ki = 0.3uM), and highly isoform-selective PIM inhibitor (IC50 = 2.5, 2.5, and 0.047uM against PIM1, PIM2, and PIM3, respectively; [ATP] = 10uM), while affecting CK2alpha2 only at much higher concentrations (IC50 = 5uM, [ATP] = 10uM) and exhibiting little or no activity against a panel of 258 other kinases (<40% inhibition at 5uM). Shown to inhibit PIM3-dependent STAT3 Tyr705 phosphorylation in DU-145 prostate cancer and MiaPaCa2 pancreatic cancer cells (by 73% and 83%, respectively; 10uM for 18h), while displaying little effect toward STAT3 Tyr694 phosphoylation in 22RV1 cultures. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
PIM447
PIM447 (LGH447) is a potent, orally available, and selective pan- PIM kinase inhibitor, with K i values of 6, 18, and 9 pM for PIM1, PIM2, and PIM3, respectively. PIM447 displays dual antimyeloma and bone-protective effects. PIM447 induces apoptosis [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LGH447. CAS No. 1210608-43-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-19322.
PIM-447 dihydrochloride
PIM447 dihydrochloride (LGH447 dihydrochloride) is a potent, orally available, and selective pan- PIM kinase inhibitor, with K i values of 6, 18, and 9 pM for PIM1, PIM2, and PIM3, respectively. PIM447 dihydrochloride displays dual antimyeloma and bone-protective effects. PIM447 dihydrochloride induces apoptosis [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LGH447 dihydrochloride. CAS No. 1820565-69-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19322B.
pimaradiene synthase
Isolated from the plants Pinus banksiana (jack pine) and Pinus contorta (lodgepole pine). Group: Enzymes. Synonyms: PbmPIM1; PcmPIM1. Enzyme Commission Number: EC 4.2.3.147. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5161; pimaradiene synthase; EC 4.2.3.147; PbmPIM1; PcmPIM1. Cat No: EXWM-5161.
Pimaric
Pimaric. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 13α-Methyl-13-vinylpodocarp-8(14)-en-15-oic acid. Product Category: Chlorinated Phenol and Resin Acids Standards. CAS No. 127-27-5. Molecular formula: C20H30O2. Mole weight: 302.45. Purity: 75-90%. Product ID: ACM127275-1. Alfa Chemistry ISO 9001:2015 Certified. Categories: Pimaric acid.
It is produced by the strain of Str. natalensis NRRL 2651, Str. gilvosporeus. It's a polyene macrolide antibiotic with strong antifungal effect. Synonyms: Myprozine; Natamycin; Delvolan; Delvocid; Natacyn; Natafucin; Pimafucin; Pimafugin; Tennecetin; Synogil; Antibiotic A-5283; Natamicina; 16-(3-Amino-3,6-didesoxy-beta-D-mannopyranosyloxy)-5,6-epoxy-8,12,14-trihydroxy-26-methyl-2,10-dioxo-1-oxacyclohexacosa-3,17,19,21,23-pentaen-13-carbonsaeure. Grade: ≥98%. CAS No. 7681-93-8. Molecular formula: C33H47NO13. Mole weight: 665.73.
Pimaricin
from Streptomyces chattanoogensis, ?95% (HPLC). Group: Pesticides & metabolites standardspharma & vet compounds & metabolitesstandards for environmental regulatory methodspharma & vet compounds & metabolites. Alternative Names: Natamax lactose, 6,11,28-Trioxatricyclo[22.3.1.05,7]octacosane, pimaricin deriv., Myprozine,6,11,28-Trioxatricyclo[22.3.1.05,7]octacosa-8,14,16,18,20-pentaene-25-carboxylic acid, 22-[(3-amino-3,6-dideoxy-?-D-mannopyranosyl)oxy]-1,3,26-trihydroxy-12-methyl-10-oxo-, (1R,3S,5R,7R,8E,12R,14E,16E,18E,20E,22R,24S,25R,26S)-, [1R-(1R*,3S*,5R*,7R*,8E,12R*,14E,16E,18E,20E,22R*,24S*,25R*,26S*)]-22-[(3-Amino-3,6-dideoxy-?-D-mannopyranosyl)oxy]-1,3,26-trihydroxy-12-methyl-10-oxo-6,11,28-trioxatricyclo[22.3.1.05,7]octacosa-8,14,16,18,20-pentaene-25-carboxylic acid, Antibiotic A 5283, Delvocid, Pimaricin (6CI,8CI), 6,11,28-Trioxatricyclo[22.3.1.05,7]octacosa-8,14,16,18,20-pentaene-25-carboxylic acid, 22-[(3-amino-3,6-dideoxy-?-D-mannopyranosyl)oxy]-1,3,26-trihydroxy-12-methyl-10-oxo-, [1R-(1R*,3S*,5R*,7R*,8E,12R*,14E,16E,18E,20E,22R*,24S*,25R*,26S*)]-, CL 12625, Natacyn, Natamax, Pimafucin, Natamax SF, Natajen, Natamycin, E 235, Synogil, Mycophyt, Myuprozine, ?-Natamycin, Tennecetin (7CI).
Pimasertib
Pimasertib (AS703026) is a highly selective, ATP non-competitive allosteric orally available MEK1/2 inhibitor [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AS703026; MSC1936369B. CAS No. 1236699-92-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12042.
Pimavanserin
Pimavanserin is a selective inverse agonist of the 5-HT2A receptor with pIC 50 and pK d of 8.73 and 9.3, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ACP-103. CAS No. 706779-91-1. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14557.
Pimavanserin-[d4], is the labelled analogue of Pimavanserin, which is an atypical antipsychotic. Synonyms: Pimavanserin-d4; Pimavanserin d4. Molecular formula: C25H30D4FN3O2. Mole weight: 431.59.
Pimavanserin hemitartrate
Pimavanserin (ACP-103) hemitartrate is a potent 5-HT 2A receptor inverse agonist with pIC 50 and pK i of 8.73 and 9.3, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ACP-103 hemitartrate. CAS No. 706782-28-7. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14557A.
Pimavanserin Impurity 18
Pimavanserin Impurity 18. Uses: For analytical and research use. Group: Impurity standards. CAS No. 107456-06-4. Molecular formula: C14H15NO2. Mole weight: 229.28. Catalog: APB107456064.
Pimavanserin Impurity 2
Pimavanserin Impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 134227-41-1. Molecular formula: C14H13F2N. Mole weight: 233.26. Catalog: APB134227411.
Pimavanserin Impurity 20
Pimavanserin Impurity 20. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1134815-53-4. Molecular formula: C21H26FN3O2. Mole weight: 371.46. Catalog: APB1134815534.
Pimavanserin Impurity 24
Pimavanserin Impurity 24. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1246458-13-8. Molecular formula: C25H32FN3O2. Mole weight: 425.55. Catalog: APB1246458138.
Pimavanserin Impurity 33
Pimavanserin Impurity 33. Uses: For analytical and research use. Group: Impurity standards. CAS No. 133067-71-7. Molecular formula: C8H10Cl2N2S. Mole weight: 237.14. Catalog: APB133067717.
Pimavanserin Impurity 42
Pimavanserin Impurity 42. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1080491-31-1. Molecular formula: C29H40FN3O8. Mole weight: 577.65. Catalog: APB1080491311.
Pimavanserin N-Oxide
Pimavanserin N-Oxide. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1134815-71-6. Molecular formula: C25H34FN3O3. Mole weight: 443.55. Catalog: APB1134815716.
Pimecrolimus
Macrolactam ascomycin derivative; inhibits production of pro-inflammatory cytokines by T cells and mast cells. Immunosuppresant. Group: Biochemicals. Alternative Names: 33-Epichloro-33-desoxyascomycin; 33-epi-Chloro-33-desoxyascomycin; ASM 981; Elidel; Picrolimus; SDZ-ASM 981. Grades: Highly Purified. CAS No. 137071-32-0. Pack Sizes: 10mg, 25mg, 50mg, 100mg. Molecular Formula: C43H68ClNO11, Melting Point: 142-144°C. US Biological Life Sciences.
Worldwide
Pimecrolimus
Pimecrolimus (SDZ-ASM 981) is a potent, nonsteroid and orally active calcineurin inhibitor with a K i of 117 nM. Pimecrolimus shows anti-inflammatory activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SDZ-ASM 981. CAS No. 137071-32-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-13723.
Pimecrolimus is an immunomodulator of calcineurin inhibitors produced by Streptomyces. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: 33-epi-Chloro-33-desoxyascomycin; ASM-981; ASM981; ASM 981; SDZ ASM 981; SDZ-ASM 981; SDZ-ASM-981. Grade: >98%. CAS No. 137071-32-0. Molecular formula: C43H68ClNO11. Mole weight: 810.45.
Pimecrolimus (Elidel, SDZ-ASM-981, D05480)
Pimecrolimus, a rapamycin (sirolimus) derivative, is a cell-selective inhibitor of inflammatory cytokines developed for the treatment of inflammatory skin diseases, such as allergic contact dermatitis, atopic dermatitis, plaque-type psoriasis, and irritant contact dermatitis. It reduces the production of inflammatory cytokines in T cells and mast cells and inhibits the release of preformed inflammatory mediators from mast cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 137071-32-0. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Pimecrolimus impurity 2
Pimecrolimus impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1025113-89-6. Molecular formula: C42H66ClNO11. Mole weight: 796.44. Catalog: APB1025113896.
Pimelic acid
Pimelic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 111-16-0. Pack Sizes: 50g, 100g, 250g, 500g, 1kg. Molecular Formula: C7H12O4. US Biological Life Sciences.
Worldwide
Pimelic acid
Pimelic acid is the organic compound and its derivatives are involved in the biosynthesis of the amino acid called lysine.Pimelic acid can be used in keratoconus research [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Heptanedioic acid; 1,5-Pentanedicarboxylic acid; 1,7-Heptanedioic acid. CAS No. 111-16-0. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-Y1139.
Pimelic acid 99+%
Pimelic acid 99+%. Group: Biochemicals. Grades: Reagent Grade. CAS No. 111-16-0. Pack Sizes: 100g, 250g, 1Kg. US Biological Life Sciences.
Worldwide
Pimelic Acid-[d4]
Pimelic Acid-[d4]. Synonyms: Pimelic Acid D4. Grade: 98% atom D. CAS No. 19031-56-2. Molecular formula: C7H8D4O4. Mole weight: 164.19.
A heme-thiolate protein (P-450). The enzyme catalyses an oxidative C-C bond cleavage of long-chain acyl-[acyl-carrier protein]s of various lengths to generate pimeloyl-[acyl-carrier protein], an intermediate in the biosynthesis of biotin. The preferred substrate of the enzyme from the bacterium Bacillus subtilis is palmitoyl-[acyl-carrier protein] which then gives heptanal as the alkanal. The mechanism is similar to EC 1.14.15.6, cholesterol monooxygenase (side-chain-cleaving), followed by a hydroxylation step, which may occur spontaneously. Group: Enzymes. Synonyms: bioI (gene name); P450BioI; CYP107H1. Enzyme Commission Number: EC 1.14.15.12. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0937; pimeloyl-[acyl-carrier protein] synthase; EC 1.14.15.12; bioI (gene name); P450BioI; CYP107H1. Cat No: EXWM-0937.
Pimeloyl-CoA
Pimeloyl-CoA is a biotin precursor of Escherichia coli. Pimeloyl-CoA can be used for the research of the pathway of de novo biotin biosynthesis in Escherichia coli [1]. Uses: Scientific research. Group: Natural products. CAS No. 18907-20-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-142080.
pimeloyl-CoA dehydrogenase
Involved in the benzoate degradation (anaerobic) pathway in bacteria. Group: Enzymes. Enzyme Commission Number: EC 1.3.1.62. CAS No. 276682-23-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1331; pimeloyl-CoA dehydrogenase; EC 1.3.1.62; 276682-23-6. Cat No: EXWM-1331.
Involved in biotin biosynthesis in Gram-negative bacteria. The enzyme exhibits carboxylesterase activity, particularly toward substrates with short acyl chains. Even though the enzyme can interact with coenzyme A thioesters, the in vivo role of the enzyme is to hydrolyse the methyl ester of pimeloyl-[acyl carrier protein], terminating the part of the biotin biosynthesis pathway that is catalysed by the fatty acid elongation enzymes. Group: Enzymes. Synonyms: BioH. Enzyme Commission Number: EC 3.1.1.85. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3514; pimelyl-[acyl-carrier protein] methyl ester esterase; EC 3.1.1.85; BioH. Cat No: EXWM-3514.
Pimento Leaf Oil WONF. CAS No. MIXTURE. Kosher: Y. VIGON Item # 500327. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers.
America & Internationally
Pimethixene maleate
Pimethixene maleate is antihistamine and antiserotonergic compound, acts as an antimigraine agent. Pimethixene maleate is a highly potent antagonist of 5-HT 1A , 5-HT 2A , 5-HT 2B , 5-HT 2C , histamine H 1 , dopamine D 2 and D 4.4 as well as muscarinic M 1 and M 2 receptors, with pK i s of 7.63, 10.22, 10.44, 8.42, 10.14, 8.19, 7.54, 8.61 and 9.38, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Pimetixene maleate. CAS No. 13187-06-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-B1101A.