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| Product | Description | |
|---|---|---|
| Pimasertib | Pimasertib (AS703026) is a highly selective, ATP non-competitive allosteric orally available MEK1/2 inhibitor [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AS703026; MSC1936369B. CAS No. 1236699-92-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12042. |  |
| Pimasertib | Pimasertib, also known as AS703026, SAR245509, MSC1936369B, is an orally bioavailable small-molecule inhibitor of MEK1 and MEK2 (MEK1/2) with potential antineoplastic activity. MEK inhibitor AS703026 selectively binds to and inhibits the activity of MEK1/2, preventing the activation of MEK1/2-dependent effector proteins and transcription factors, which may result in the inhibition of growth factor-mediated cell signaling and tumor cell proliferation. Synonyms: SAR245509; SAR-245509; SAR 245509; MSC1936369B; AS-703026; AS 703026; AS703026. Grades: 0.98. CAS No. 1236699-92-5. Molecular formula: C15H15FIN3O3. Mole weight: 431.206. |  |
| Pimavanserin | Pimavanserin is a selective inverse agonist of the 5-HT2A receptor with pIC 50 and pK d of 8.73 and 9.3, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ACP-103. CAS No. 706779-91-1. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14557. | |
| Pimavanserin | Pimavanserin is a potent and selective 5-HT2A receptor inverse agonist used in the treatment of Parkinson's disease psychosis. Uses: Drug used in the treatment of parkinson's disease psychosis. Synonyms: ACP-103; AC-5273; ACP 103; AC 5273; ACP103; AC5273;1-(4-Fluorobenzyl)-3-(4-isobutoxybenzyl)-1-(1-methylpiperidin-4-yl)urea. Grades: ≥95%. CAS No. 706779-91-1. Molecular formula: C25H34FN3O2. Mole weight: 427.55. | |
| Pimavanserin | Pimavanserin. Group: Biochemicals. Alternative Names: N- (4-Fluorobenzyl) -N- (1-methylpiperidin-4-yl) -N'- [ [4- (2-methylpropyloxy) phenyl] methyl] carbamide; N-[ (4-Fluorophenyl) methyl]-N- (1-methyl-4-piperidinyl) -N'-[[4- (2-methylpropoxy) phenyl]methyl]urea. Grades: Highly Purified. CAS No. 706779-91-1. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C25H34FN3O2. US Biological Life Sciences. |  Worldwide |
| Pimavanserin-d4 | Cas No. 706779-91-1. | |
| Pimavanserin hemitartrate | Pimavanserin (ACP-103) hemitartrate is a potent 5-HT 2A receptor inverse agonist with pIC 50 and pK i of 8.73 and 9.3, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ACP-103 hemitartrate. CAS No. 706782-28-7. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14557A. | |
| Pimavanserin Impurity 18 | Pimavanserin Impurity 18. Uses: For analytical and research use. Group: Impurity standards. CAS No. 107456-06-4. Molecular formula: C14H15NO2. Mole weight: 229.28. Catalog: APB107456064. |  |
| Pimavanserin Impurity 2 | Pimavanserin Impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 134227-41-1. Molecular formula: C14H13F2N. Mole weight: 233.26. Catalog: APB134227411. | |
| Pimavanserin Impurity 20 | Pimavanserin Impurity 20. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1134815-53-4. Molecular formula: C21H26FN3O2. Mole weight: 371.46. Catalog: APB1134815534. | |
| Pimavanserin Impurity 24 | Pimavanserin Impurity 24. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1246458-13-8. Molecular formula: C25H32FN3O2. Mole weight: 425.55. Catalog: APB1246458138. | |
| Pimavanserin Impurity 33 | Pimavanserin Impurity 33. Uses: For analytical and research use. Group: Impurity standards. CAS No. 133067-71-7. Molecular formula: C8H10Cl2N2S. Mole weight: 237.14. Catalog: APB133067717. | |
| Pimavanserin Impurity 42 | Pimavanserin Impurity 42. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1080491-31-1. Molecular formula: C29H40FN3O8. Mole weight: 577.65. Catalog: APB1080491311. | |
| Pimavanserin N-Oxide | Pimavanserin N-Oxide. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1134815-71-6. Molecular formula: C25H34FN3O3. Mole weight: 443.55. Catalog: APB1134815716. | |
| Pimavanserin tartrate | Pimavanserin is a potent and selective serotonin 5-HT2A inverse agonist. It has been used as an atypical antipsychotic in the treatment of psychosis associated with Parkinson's disease. Uses: Antiparkinson agents. Synonyms: ACP-103; Nuplazid1-[(4-fluorophenyl)methyl]-1-(1-methylpiperidin-4-yl)-3-[[4-(2-methylpropoxy)phenyl]methyl]urea tartrate. CAS No. 706782-28-7. Molecular formula: C50H68F2N6O4·C4H6O6. Mole weight: 1005.2. | |
| Pimecrolimus | Pimecrolimus (SDZ-ASM 981) is a potent, nonsteroid and orally active calcineurin inhibitor with a K i of 117 nM. Pimecrolimus shows anti-inflammatory activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SDZ-ASM 981. CAS No. 137071-32-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-13723. | |
| Pimecrolimus | Pimecrolimus. CAS No. 137071-32-0. Product ID: 8-04401. Molecular formula: C43H68NO11Cl. Mole weight: 810.47. |  |
| Pimecrolimus | Macrolactam ascomycin derivative; inhibits production of pro-inflammatory cytokines by T cells and mast cells. Immunosuppresant. Group: Biochemicals. Alternative Names: 33-Epichloro-33-desoxyascomycin; 33-epi-Chloro-33-desoxyascomycin; ASM 981; Elidel; Picrolimus; SDZ-ASM 981. Grades: Highly Purified. CAS No. 137071-32-0. Pack Sizes: 10mg, 25mg, 50mg, 100mg. Molecular Formula: C43H68ClNO11, Melting Point: 142-144°C. US Biological Life Sciences. | Worldwide |
| Pimecrolimus | ?97% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Pimecrolimus (Elidel, SDZ-ASM-981, D05480) | Pimecrolimus, a rapamycin (sirolimus) derivative, is a cell-selective inhibitor of inflammatory cytokines developed for the treatment of inflammatory skin diseases, such as allergic contact dermatitis, atopic dermatitis, plaque-type psoriasis, and irritant contact dermatitis. It reduces the production of inflammatory cytokines in T cells and mast cells and inhibits the release of preformed inflammatory mediators from mast cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 137071-32-0. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Pimecrolimus impurity 2 | Pimecrolimus impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1025113-89-6. Molecular formula: C42H66ClNO11. Mole weight: 796.44. Catalog: APB1025113896. | |
| Pimelic acid | Pimelic acid is the organic compound and its derivatives are involved in the biosynthesis of the amino acid called lysine.Pimelic acid can be used in keratoconus research [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Heptanedioic acid; 1,5-Pentanedicarboxylic acid; 1,7-Heptanedioic acid. CAS No. 111-16-0. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-Y1139. | |
| Pimelic acid | Pimelic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 111-16-0. Pack Sizes: 50g, 100g, 250g, 500g, 1kg. Molecular Formula: C7H12O4. US Biological Life Sciences. | Worldwide |
| Pimelic acid 99+% | Pimelic acid 99+%. Group: Biochemicals. Grades: Reagent Grade. CAS No. 111-16-0. Pack Sizes: 100g, 250g, 1Kg. US Biological Life Sciences. | Worldwide |
| Pimelic Diphenylamide 106 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| pimeloyl-[acyl-carrier protein] synthase | A heme-thiolate protein (P-450). The enzyme catalyses an oxidative C-C bond cleavage of long-chain acyl-[acyl-carrier protein]s of various lengths to generate pimeloyl-[acyl-carrier protein], an intermediate in the biosynthesis of biotin. The preferred substrate of the enzyme from the bacterium Bacillus subtilis is palmitoyl-[acyl-carrier protein] which then gives heptanal as the alkanal. The mechanism is similar to EC 1.14.15.6, cholesterol monooxygenase (side-chain-cleaving), followed by a hydroxylation step, which may occur spontaneously. Group: Enzymes. Synonyms: bioI (gene name); P450BioI; CYP107H1. Enzyme Commission Number: EC 1.14.15.12. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0937; pimeloyl-[acyl-carrier protein] synthase; EC 1.14.15.12; bioI (gene name); P450BioI; CYP107H1. Cat No: EXWM-0937. |  |
| Pimeloyl-CoA | Pimeloyl-CoA is a biotin precursor of Escherichia coli. Pimeloyl-CoA can be used for the research of the pathway of de novo biotin biosynthesis in Escherichia coli [1]. Uses: Scientific research. Group: Natural products. CAS No. 18907-20-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-142080. | |
| pimeloyl-CoA dehydrogenase | Involved in the benzoate degradation (anaerobic) pathway in bacteria. Group: Enzymes. Enzyme Commission Number: EC 1.3.1.62. CAS No. 276682-23-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1331; pimeloyl-CoA dehydrogenase; EC 1.3.1.62; 276682-23-6. Cat No: EXWM-1331. | |
| pimelyl-[acyl-carrier protein] methyl ester esterase | Involved in biotin biosynthesis in Gram-negative bacteria. The enzyme exhibits carboxylesterase activity, particularly toward substrates with short acyl chains. Even though the enzyme can interact with coenzyme A thioesters, the in vivo role of the enzyme is to hydrolyse the methyl ester of pimeloyl-[acyl carrier protein], terminating the part of the biotin biosynthesis pathway that is catalysed by the fatty acid elongation enzymes. Group: Enzymes. Synonyms: BioH. Enzyme Commission Number: EC 3.1.1.85. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3514; pimelyl-[acyl-carrier protein] methyl ester esterase; EC 3.1.1.85; BioH. Cat No: EXWM-3514. | |
| Pimelyl Dihydrazide | White crystalline, 98%. Synonyms: Heptanedioic Acid Dihydrazide. CAS No. 13043-98-6. Pack Sizes: 5g, 25g. Product ID: FR-0262. M.P. 182-185. Mole weight: 188.23. |  Frinton Laboratories |
| Pimento Berry WONF | Pimento Berry WONF. CAS No. MIXTURE. Kosher: Y. VIGON Item # 500324. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers. |  America & Internationally |
| Pimento Leaf Oil | Pimento Leaf Oil. CAS No. MIXTURE. Kosher: Y. VIGON Item # 500326. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers. | America & Internationally |
| Pimento Leaf Oil Redistilled | Pimento Leaf Oil Redistilled. CAS No. MIXTURE. Kosher: Y. VIGON Item # 504748. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers, Aromatherapy, Essetial Oils. | America & Internationally |
| Pimento Leaf Oil WONF | Pimento Leaf Oil WONF. CAS No. MIXTURE. Kosher: Y. VIGON Item # 500327. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers. | America & Internationally |
| Pimethixene | Pimethixene, also called as BP 400 or Calmixène, with antihistamine and anticholinergic properties it treats hyperactivity, anxiety, sleep disorders, and allergy. Synonyms: 1-methyl-4-thioxanthen-9-ylidenepiperidine1-methyl-4-thioxanthen-9-ylidenepiperidineBP 400; BP400; BP-400Calmixènepimethixene. CAS No. 314-03-4. Molecular formula: C19H19NS. Mole weight: 293.432. | |
| Pimethixene maleate | Pimethixene maleate is antihistamine and antiserotonergic compound, acts as an antimigraine agent. Pimethixene maleate is a highly potent antagonist of 5-HT 1A , 5-HT 2A , 5-HT 2B , 5-HT 2C , histamine H 1 , dopamine D 2 and D 4.4 as well as muscarinic M 1 and M 2 receptors, with pK i s of 7.63, 10.22, 10.44, 8.42, 10.14, 8.19, 7.54, 8.61 and 9.38, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Pimetixene maleate. CAS No. 13187-06-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-B1101A. | |
| Pimethixene Maleate | Pimethixene, also called as BP 400 or Calmixène, with antihistamine and anticholinergic properties it treats hyperactivity, anxiety, sleep disorders, and allergy. Synonyms: 9-(1-methyl-4-piperidylene)thioxanthenemaleate; 9-(1-methyl-4-piperidylene)-thioxanthenmaleate; 9-(n-methyl-piperidyliden-4)thioxanemaleate; bp-400; PIMETHIXENE MALEATE; PIMETHIXENE MALEATE SALT; PIMETHIXEN MALEATE SALT; 1-METHYL-4-[THIOXANTHEN-9-YLIDENE]PIPERI. Grades: > 95%. CAS No. 13187-06-9. Molecular formula: C19H19NS.C4H4O4. Mole weight: 409.5. | |
| Pimicotinib | Pimicotinib is a CSF1R inhibitor with antitumor activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABSK021. CAS No. 2253123-16-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153920. | |
| PIM inhibitor 1 phosphate | PAK4-IN-1 is an inhibitor of Pim (IC50 < 35 nM). Synonyms: 2-Pyridinecarboxamide, N-[(7R)?-4-[(3R,?4R,?5S)?-3-amino-4-hydroxy-5-methyl-1-piperidinyl]?-6,?7-dihydro-7-hydroxy-5H-cyclopenta[b]?pyridin-3-yl]?-6-(2,?6-difluorophenyl)?-5-fluoro-, phosphate (1:1). CAS No. 2088852-47-3. Molecular formula: C26H29F3N5O7P. Mole weight: 611.51. | |
| Piminodine dihydrochloride | Piminodine dihydrochloride. Group: Biochemicals. Alternative Names: 4-Phenyl-1-[3-(phenylamino)propyl]-4-piperidinecarboxylic acid ethyl ester hydrochloride; 1-(3-Anilinopropyl)-4-phenylisonipecotic acid ethyl ester dihydrochloride; Anopridine dihydrochloride. Grades: Highly Purified. CAS No. 113862-30-9. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C23H32Cl2N2O2. US Biological Life Sciences. | Worldwide |
| Pimitespib | Pimitespib (TAS-116) is an oral bioavailable, ATP-competitive, highly specific HSP90α/HSP90β inhibitor ( K i s of 34.7 nM and 21.3 nM, respectively) without inhibiting other HSP90 family proteins such as GRP94 [1]. Pimitespib demonstrates less ocular toxicity [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAS-116. CAS No. 1260533-36-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15785. | |
| PIM-Kinase Inhibitor IX, SGI-1776 (N- ( (1-Methylpiperidin-4-yl) methyl) -3- (3- (trifluoromethoxy) phenyl) imidazo[1, 2-b]pyridazin-6-amine, 2H2SO4) | A cell-permeable imidazopyridazine compound that acts as a potent, reversible and ATP-competitive inhibitor of Pim-1,2,3, Flt-3 and haspin kinase activities (IC50=7, 363, 69, 44 and 34nM, respectively) with moderate (40% inhibition at 1uM for c-kit) to excellent selectivity over CDKs, Aurora, Chk1, IKK, JNK, Abl, Raf, PKA, PKC and PI 3-K among 300-kinases. Shown to inhibit RNA synthesis, block phosphorylation of c-Myc-Ser62 and STAT3-Tyr705, and decrease c-Myc and Mcl-1 protein levels; cause cell cycle arrest and induce apoptosis in CLL lymphocytes and in AML cells, and efficiently arrest the growth of several prostate cancer cells (IC50 <10uM). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??F?N?O; 2H?SO?, Molecular Weight: 601.6. US Biological Life Sciences. | Worldwide |
| PIM Kinase Inhibitor VIII, R8-T198wt (NH2-GGGRRRRRRRRGC ~KKPGLRRRQT-CO2H, cpm-P27Kip1189-198) | The human p27Kip1 C-terminus PIM-1 phosphorylation site- (Thr198) containing sequence is synthesized with an N-terminal Arg octamer/R8-containing sequence to facilitate its use as a cell-permeable, substrate-competitive PIM-1 inhibitor. Reported to completely prevents human prostate carcinoma DU145-derived tumor expansion for up to 17 days (0.5umol/animal on days 0 & 5; intratumoral injection) in mice in vivo when combined with a single Taxol dosage on day zero (60mg/kg; i.p.). Studies using FITC-conjugated R8-T198wt demonstrate that R8-T198wt-induced cell cycle arrest and apoptosis in PIM-1-expressing DU145 cells are direct consequences of inhibition of PIM-1-mediated p27Kip1 Thr198 and Bad Ser112 phosphorylation, respectively. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Pimobendan | Pimobendan is both a calcium sensitizer and a selective inhibitor of phosphodiesterase III (PDE3) with positive inotropic and vasodilator effects. Uses: Phosphodiesterase inhibitors. Synonyms: Alprostadil;UD-CG115; UD CG115; UD-CG 115; UD-CG-115; Pimobendan; pimobendane. Trade name: Vetmedin and Acardi. Grades: >98%. CAS No. 74150-27-9. Molecular formula: C19H18N4O2. Mole weight: 334.37. | |
| Pimobendan | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopypharma & vet compounds & metabolitespharma & vet compounds & metabolitesapi standardsbritish pharmacopoeiaeuropean pharmacopoeia (ph. eur.)pharmacopoeial standards. Alternative Names: Vetmedin,(5RS)-6-[2-(4-Methoxyphenyl)-1H-benzimidazol-5-yl]-5-methyl-4,5-dihydropyridazin-3(2H)-one, 3(2H)-Pyridazinone, 4,5-dihydro-6-[2-(4-methoxyphenyl)-1H-benzimidazol-6-yl]-5-methyl-, Racemic pimobendan, dl-Pimobendan, 4,5-Dihydro-6-[2-(4-methoxyphenyl)-1H-benzimidazol-6-yl]-5-methyl-3(2H)-pyridazinone, Acardi, UD-CG 115BS, 3(2H)-Pyridazinone, 4,5-dihydro-6-[2-(4-methoxyphenyl)-1H-benzimidazol-5-yl]-5-methyl- (9CI), Pimobendan, 3(2H)-Pyridazinone, 4,5-dihydro-6-[2-(4-methoxyphenyl)-1H-benzimidazol-5-yl, UD-CG 115. | |
| Pimobendan | Pimobendan. Group: Biochemicals. Grades: Highly Purified. CAS No. 74150-27-9. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. US Biological Life Sciences. | Worldwide |
| Pimobendan | Pimobendan (UD-CG115) is a selective inhibitor of PDE3 with IC 50 of 0.32 μM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: UD-CG115. CAS No. 74150-27-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-B0204. | |
| Pimobendan EP | (RS)-6-[2-(4-methoxyphenyl)-1H-benzimidazol-5-yl]-5-methyl-4,5-dihydropyridazin-3(2H)-one. Grades: EP. CAS No. 74150-27-9. Product ID: 8-04714. Molecular formula: C19H18N4O2. Mole weight: 334.37. | |
| Pimobendan hydrochloride | Pimobendan hydrochloride is a selective inhibitor of PDE3. It exhibits selective inhibition of PDE III isolated from guinea pig cardiac muscle with IC50 of 0.32 uM compared to the inhibition of PDE I and PDE II (IC50s >30 μM). It shows a beneficial effect on survival in the murine model of EMC virus-induced myocarditis. It also significantly reduces myocardial cellular infiltration, the level of intracardiac tumor necrosis factor (TNF)-α and interleukin (IL)-1β compared with the control group, which shows no effect on myocardial necrosis, heart weight and body weight. It suppresses expression of the intracardiac iNOS gene , causing reduction of intracardiac NO production. Synonyms: Vetmedin hydrochloride; Acardi hydrochloride. Grades: >98%. CAS No. 77469-98-8. Molecular formula: C19H19ClN4O2. Mole weight: 370.83. | |
| Pimobendan Impurity A | An impurity of Pimobendan which is both a calcium sensitizer and a selective inhibitor of phosphodiesterase III (PDE3) with positive inotropic and vasodilator effects. Grades: > 95%. Molecular formula: C19H18N2O4. Mole weight: 338.37. | |
| Pimobendan Impurity B | An impurity of Pimobendan which is a calcium sensitizer and a selective inhibitor of phosphodiesterase 3 (PDE3) with positive inotropic and vasodilator effects. Grades: > 95%. Molecular formula: C19H20N4O3. Mole weight: 352.4. | |
| Pimobenden | 100mg Pack Size. Group: Bioactive Small Molecules. Formula: C19H18N4O2. CAS No. 74150-27-9. Prepack ID 69675966-100mg. Molecular Weight 334.37. See USA prepack pricing. |  |
| Pimodivir | Pimodivir (VX-787) is an orally bioavailable inhibitor of influenza A virus polymerases through interaction with the viral PB2 subunit. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VX-787. CAS No. 1629869-44-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12353A. | |
| Pimonidazole | Pimonidazole is a novel hypoxia marker for complementary study of tumor hypoxia and cell proliferation in tumor [1]. Pimonidazole accumulates in hypoxic cells via covalent binding with macromolecules or by forming reductive metabolites after reduction of its nitro group, it can be used for qualitative and quantitative assessment of tumor hypoxia [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 70132-50-2. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-105129A. | |
| Pimonidazole | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Pimonidazole | Pimonidazole, also known as Ro 03-8799 and PD 126675, is a nitroimidazole drug with hypoxic selectivity and radiosensitizing property. Pimonidazole is reduced in hypoxic environments as in tumor cells, thereby it can be used as an hypoxia marker. In hypoxic cells, reduced pimonidazole binds to -SH-containing molecules such as glutathione and proteins, and the resulting complexes accumulated in tissues, thereby sensitizing cells to be more susceptible for radiation treatment. Synonyms: NSC 380540; NSC-380540; NSC380540; PD 126675; PD126675; PD-126675; Ro 03-8799. Grades: >98%. CAS No. 70132-50-2. Molecular formula: C11H18N4O3. Mole weight: 254.29. | |
| Pimonidazole hydrochloride | Pimonidazole is a novel hypoxia marker for complementary study of tumor hypoxia and cell proliferation in tumor [1]. Pimonidazole accumulates in hypoxic cells via covalent binding with macromolecules or by forming reductive metabolites after reduction of its nitro group, it can be used for qualitative and quantitative assessment of tumor hypoxia [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 70132-51-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-105129. | |
| Pimozide | Pimozide is a dopamine receptor antagonist, with K i s of 1.4 nM, 2.5 nM and 588 nM for dopamine D2, D3 and D1 receptors, respectively, and also has affinity at α1-adrenoceptor , with a K i of 39 nM; Pimozide also inhibits STAT3 and STAT5. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R6238. CAS No. 2062-78-4. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-12987. | |
| Pimozide | Pimozide is a diphenylbutylpiperidine derivative and a dopamine antagonist with antipsychotic property. Pimozide selectively inhibits type 2 dopaminergic receptors in the central nervous system (CNS), and also inhibits STAT3 and STAT5. Uses: Anti-dyskinesia agents. Synonyms: R6238. Grades: 98%. CAS No. 2062-78-4. Molecular formula: C28H29F2N3O. Mole weight: 461.55. | |
| Pimozide Impurity A | An impurity of Pimozide (Orap) which has special neurologic indications for Tourette syndrome and resistant tics. Grades: > 95%. Molecular formula: C12H15N3O. Mole weight: 217.27. | |
| Pimozide Impurity B | An impurity of Pimozide (Orap) which is used to reduce uncontrolled movements (motor tics) or outbursts of words/sounds (vocal tics) caused by Tourette syndrome. Grades: > 95%. Molecular formula: C28H30FN3O. Mole weight: 443.57. | |
| Pimozide Impurity C | An impurity of Pimozide (Orap) which is an antipsychotic drug of the diphenylbutylpiperidine class. Grades: > 95%. Molecular formula: C28H29F2N3O. Mole weight: 461.56. | |
| Pimozide Impurity D | An impurity of Pimozide (Orap) which has special neurologic indications for Tourette syndrome and resistant tics. Grades: > 95%. Molecular formula: C28H27F2N3O. Mole weight: 459.54. | |
| Pimozide Impurity E | An impurity of Pimozide (Orap) which is an antipsychotic drug of the diphenylbutylpiperidine class. Synonyms: Pimozide N-Oxide; 1083078-88-9; UNII-KC2BVV76IU; KC2BVV76IU; Pimozide specified impurity E [EP]; 1-(1-(4,4-Bis(4-fluorophenyl)butyl)piperidin-4-yl 1-oxide)-1,3-dihydro-2H-benzimidazol-2-one; 2H-Benzimidazol-2-one, 1-(1-(4,4-bis(4-fluorophenyl)butyl)-1-oxido-4-piperidinyl)-1,3-dihydro-; 3-[1-[4,4-bis(4-fluorophenyl)butyl]-1-oxidopiperidin-1-ium-4-yl]-1H-benzimidazol-2-one; Pimozide impurity E; SCHEMBL1152903; DTXSID00148496; BCP15238; PIMOZIDE IMPURITY E [EP IMPURITY]; FT-0673904; F97131; Q27282170; 210690-27-0; CIS-(1S,4R)-1-[4,4-BIS(4-FLUOROPHENYL)BUTYL]-4-(2-OXO-2,3-DIHYDRO-1H-1,3-BENZODIAZOL-1-YL)PIPERIDIN-1-IUM-1-OLATE. Grades: > 95%. Molecular formula: C28H29F2N3O2. Mole weight: 477.56. | |
| Pimozide N-Oxide | Pimozide N-Oxide is an impurity of Pimozide with hERG inhibitory activity. Pimozide impurity E. Group: Biochemicals. Alternative Names: 1-[1-[4,4-Bis(4-fluorophenyl)butyl]-1-oxido-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one. Grades: Highly Purified. CAS No. 1083078-88-9. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Pimpinellin | Pimpinellin. Group: Biochemicals. Grades: Plant Grade. CAS No. 131-12-4. Pack Sizes: 20mg. Molecular Formula: C13H10O5, Molecular Weight: 246.22. US Biological Life Sciences. | Worldwide |
| Pimprinethine | Pimprinethine is a pyrazoloisoquinolinone antibiotic produced by Streptoverticillium griseocarneum. It has weak anti-Gram-positive bacteria activity. Synonyms: APHE-1. CAS No. 146426-35-9. Molecular formula: C13H12N2O. Mole weight: 212.25. | |
| Pimprinine | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Pimprinine (3-(2-Methyl-5-oxazolyl)-1H-indole, Antibiotic WS-30581C, NSC80793, 5-(3-Indoyl)-2-methyloxazole) | Indole alkaloid. Monoamine oxidase inhibitor (MAOI). Antiepileptic (anticonvulsant) compound. Inhibitor of platelet aggregation and thromboxane A2 synthesis. Weak antifungal and antituberculosis activity. Useful as lead structure for potent antifungal substances. Group: Biochemicals. Grades: Highly Purified. CAS No. 13640-26-1. Pack Sizes: 1mg, 5mg. Molecular Formula: C12H10N2O, Molecular Weight: 198.2. US Biological Life Sciences. | Worldwide |
| Pimprinine (5-(3-Indolyl)-2-methyloxazole, Antibiotic WS 30581C, Antibiotic APHE 3) | Pimprinine is an indole alkaloid produced by many species of Streptomyces. Pimprinine is a potent inhibitor of monoamine oxidase and has shown antiepileptic effects. More recently, pimprinine showed promising anticonvulsant activity in electric seizure threshold tests in mice, comparable to phenyl hydantoin. Pimprinine also inhibited tremorine-induced tremors and analgesia in mice. Group: Biochemicals. Alternative Names: 5-(3-Indolyl)-2-methyloxazole, Antibiotic WS 30581C, Antibiotic APHE 3. Grades: Highly Purified. CAS No. 13640-26-1. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
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