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| Product | Description | |
|---|---|---|
| PLGA-PEG-PLGA (Mn (1000-1000-1000)) | PLGA-PEG-PLGA is an amphiphilic triblock copolymer which can self-assemble into micelles in aqueous medium due to the hydrophobic interactions present in the hydrophobic segments. The PEG segment imparts hydrophilicity and improves the biocompatibility of the copolymer. The PLGA segment forms a hydrophobic core and can solubilize hydrophobic drugs. These copolymers are widely used as nanocarriers for the sustained release of drugs. Synonyms: Poly(lactide-co-glycolide)-block-poly(ethylene glycol)-block-poly(lactide-co-glycolide). Product ID: MSMN-069. Category: Raw Materials. |  |
| PLGA-PEG-PLGA (Mn (1100-1000-1100)) | PLGA-PEG-PLGA is an amphiphilic triblock copolymer which can self-assemble into micelles in aqueous medium due to the hydrophobic interactions present in the hydrophobic segments. The PEG segment imparts hydrophilicity and improves the biocompatibility of the copolymer. The PLGA segment forms a hydrophobic core and can solubilize hydrophobic drugs. These copolymers are widely used as nanocarriers for the sustained release of drugs. Synonyms: Poly(lactide-co-glycolide)-block-poly(ethylene glycol)-block-poly(lactide-co-glycolide). Product ID: MSMN-068. Category: Raw Materials. | |
| PLGA-PEG-PLGA (Mn (1,600-1,500-1,600)) | PLGA-PEG-PLGA (Mn (1,600-1,500-1,600)). Synonyms: Poly(lactide-co-glycolide)-b-poly(ethylene glycol)-b-poly(lactide-co-glycolide). Product ID: MSMN-070. Category: Raw Materials. | |
| PLGA-PEG-PLGA (Mn (1,700-1,500-1,700)) | PLGA-PEG-PLGA (Mn (1,700-1,500-1,700)). Synonyms: Poly(lactide-co-glycolide)-b-poly(ethylene glycol)-b-poly(lactide-co-glycolide). Product ID: MSMN-071. Category: Raw Materials. | |
| PLGF-1 human | recombinant, expressed in E. coli, ?95% (SDS-PAGE), ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| PLGF-2 human | recombinant, expressed in E. coli, ?90% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| PLGF-3 human | recombinant, expressed in E. coli, ?95% (SDS-PAGE), ?95% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy. | |
| PLGF from mouse | recombinant, expressed in E. coli, ?95% (SDS-PAGE), ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PLGF-I human | Animal-component free, recombinant, expressed in E. coli, ?95% (SDS-PAGE), ?95% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy. | |
| Plicamycin | Plicamycin (Mithramycin A) is a selective specificity protein 1 ( Sp1 ) inhibitor. Plicamycin inhibits the growth of various cancers by decreasing Sp1 protein. Plicamycin inhibits GSTM2 promoter activity and protein expression [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Mithramycin A. CAS No. 18378-89-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0122. |  |
| Plicatol B | Plicatol B. Group: Biochemicals. CAS No. 108335-06-4. Pack Sizes: 5mg. US Biological Life Sciences. |  Worldwide |
| Plicatone | Plicatone. CAS No. 41724-19-0. VIGON Item # 502831. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers, herbal undecanone. |  America & Internationally |
| Plinabulin | Plinabulin (NPI-2358) is a vascular disrupting agen ( VDA ) against tubulin-depolymerizing with an IC 50 of 9.8 nM against HT-29 cells [1]. Plinabulin binds the colchicine binding site of β-tubulin preventing polymerization and has potent inhibitory to tumor cells [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NPI-2358. CAS No. 714272-27-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14444. | |
| Plitidepsin | Plitidepsin (Aplidine) is a potent anti-cancer agent by targeting eEF1A2 ( K D =80?nM) [1]. Plitidepsin possesses antiviral activity and is against SARS-CoV-2 with an IC 90 of 0.88 nM. Plitidepsin is usually used for multiple myeloma and advanced cancer research, and has the potential for COVID-19 research [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: Aplidine; PM90001. CAS No. 137219-37-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16050. | |
| Plitidepsin | Plitidepsin is a cyclic depsipeptide isolated from the marine tunicate Aplidium albicans. Plitidepsin shows potent anticancer activity against a large variety of cultured human cancer cells, inducing apoptosis by triggering mitochondrial cytochrome c release, initiating the Fas/DC95, JNK pathway and activating caspase 3 activation. This agent also inhibits elongation factor 1-a, thereby interfering with protein synthesis, and induces G1 arrest and G2 blockade, thereby inhibiting tumor cell growth. Synonyms: aplidin; aplidine; plitidepsin; dehydrodidemnin B. Grade: >98%. CAS No. 137219-37-5. Molecular formula: C57H87N7O15. Mole weight: 1110.34. |  |
| Plitidepsin | Plitidepsin. Uses: Designed for use in research and industrial production. Product Category: Coronavirus and Solid Tumor Clinical Raw Materials. CAS No. 137219-37-5. Purity: >98%. Product ID: ACM137219375. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Plixorafenib | PLX8394 is a potent and selective BRaf inhibitor, with an IC 50 of appr 5 nM for BRAF V600E. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PLX8394; FORE8394. CAS No. 1393466-87-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18972. | |
| PLK1, active, His tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| PLK1 Polo Box Domain active human | recombinant, expressed in E. coli, ?90% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| PLK2 Active human | recombinant, expressed in baculovirus infected insect cells, ?60% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| PLK3, active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| PLK3 Active human | recombinant, expressed in baculovirus infected insect cells, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| PLK3 Polo Box Domain human | recombinant, expressed in E. coli, ?90% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| PLK4, active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| PLL coated Fe2O3 nanoparticles | PLL coated Fe2O3 nanoparticles. Group: Nanopowders. CAS No. 1317-61-9. |  |
| PLL-g-PEG-Biotin | PLL-g-PEG-Biotin is a biotinylated poly-L-lysine PEG conjugate that was made from the covalent attachment of PEG 2000 and biotin to the Poly-L-lysine molecules. It is a positively charged PLL-g-PEG copolymer that can bind to streptavidin or avidin with high affinity. It is a linear amphiphilic block copolymer used for gene transfection or surface modification. Synonyms: Poly(L-lysine)-graft-biotinylated PEG; Biotinylated PLL-g-PEG; Poly lysine-g-polyethylene glycol-biotin. | |
| PLN-1474 | PLN-1474 (compound 1) is an orally active and selective ???1 integrin inhibitor with an IC50 value of <50 nM. PLN-1474 reduces levels of pSMAD3/SMAD3 in liver, hepatic collagen gene expression and hepatic OHP concentration in liver fibrosis mouse model. PLN-1474 can be used for the research of preventing, delaying or researching a fibrotic or cirrhotic disease or disorder. Uses: Scientific research. Group: Signaling pathways. CAS No. 2408065-32-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-47888. | |
| PlnA-17 | PlnA-17 is an antibacterial peptide isolated from Lactobacillus plantarum. It has activity against gram-positive bacteria. Grade: >95%. Molecular formula: C97H153N25O20. Mole weight: 1989.44. | |
| PlnA-22 | PlnA-22 is an antibacterial peptide isolated from Lactobacillus plantarum. It has activity against gram-positive bacteria. Synonyms: Tyr-Ser-Leu-Gln-Met-Gly-Ala-Thr-Ala-Ile-Lys-Gln-Val-Lys-Lys-Leu-Phe-Lys-Lys-Trp-Gly-Trp. Grade: >97%. Molecular formula: C125H195N31O28S. Mole weight: 2612.17. | |
| Plogosertib | Plogosertib (CYC140) is a selective, potent, and orally active ATP-competitive PLK1 inhibitor (IC50: 3 nM). Plogosertib is an anti-cancer agent with anti-proliferative activity. Plogosertib can be used in the research of several tumors, including esophageal, gastric, leukemia, non-small cell lung cancer, ovarian, and squamous cell cancers[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CYC140. CAS No. 1137212-79-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147298. | |
| Plozalizumab | Plozalizumab (MLN-1202) is a specific humanized anti- CCR2 antibody. Plozalizumab can be used for malignant melanoma research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MLN-1202. CAS No. 1610761-46-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99781. | |
| PLP (103-116) | PLP (103-116) is the 103-116 amino acid residue of myelin protein (PLP), used to induce experimental autoimmune encephalomyelitis (EAE). Synonyms: PLP 103-116; Tyr-Lys-Thr-Thr-Ile-Cys-Gly-Lys-Gly-Leu-Ser-Ala-Thr-Val. Molecular formula: C63H108N16O20S. Mole weight: 1441.60. | |
| PLP (139-151) | PLP (139-151). Group: Biochemicals. Grades: Purified. CAS No. 122018-58-0. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| PLP (139-151) | PLP (139-151) is amino acid residue 139 to 151 of myelin proteolipid protein (PLP) used to induce experimental autoimmune encephalomyelitis (EAE). Uses: Scientific research. Group: Peptides. CAS No. 131334-43-5. Pack Sizes: 5 mg. Product ID: HY-P0129. | |
| PLP 139-151 | PLP 139-151 is the 139-151 amino acid residue of myelin protein (PLP), used to induce experimental autoimmune encephalomyelitis (EAE). Synonyms: Myelin Proteolipid Protein (139-151) (depalmitoylated) (human, bovine, dog, mouse, rat); His-Cys-Leu-Gly-Lys-Trp-Leu-Gly-His-Pro-Asp-Lys-Phe; L-histidyl-L-cysteinyl-L-leucyl-glycyl-L-lysyl-L-tryptophyl-L-leucyl-glycyl-L-histidyl-L-prolyl-L-alpha-aspartyl-L-lysyl-L-phenylalanine. Grade: >98%. CAS No. 131334-43-5. Molecular formula: C72H104N20O16S. Mole weight: 1537.79. | |
| PLP (180-199) TFA | PLP (180-199) TFA is the TFA salt form of PLP (180-199) (HY-P5462). PLP (180-199) TFA induces the activation and differentiation of T cells, and induces the experimental autoimmune encephalomyelitis (EAE) in mouse model[1]. Uses: Scientific research. Group: Peptides. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P5462A. | |
| PLpro inhibitor | PLpro inhibitor is a potent inhibitor of papain-like protease (PLpro) with an IC 50 of 2.6 μM [1]. PLpro inhibitor inhibits SARS-CoV-2 PLpro with an IC 50 of 5.0 μM and an EC 50 of 21.0 μM [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1093070-14-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17542. | |
| PLU-1 human | recombinant, expressed in baculovirus infected Sf9 cells, ?55% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| PLU-1 murine | recombinant, expressed in baculovirus infected Sf9 cells, ?50% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| Plumbagin | Plumbagin. Group: Biochemicals. Grades: Purified. CAS No. 481-42-5. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| Plumbagin | Plumbagin (2-Methyljuglone) is a naphthoquinone isolated from Plumbago zeylanica , exhibits anticancer and antiproliferative activities [1]. Uses: Scientific research. Group: Natural products. Alternative Names: 2-Methyljuglone. CAS No. 481-42-5. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-N1497. | |
| Plumieride | Plumieride is isolated from the herb of Himatanthus fallax. It shows strong fungitoxicity against some dermatophytes. Synonyms: Agoniadin. Grade: 98%. CAS No. 511-89-7. Molecular formula: C21H26O12. Mole weight: 470.42. | |
| Pluracidomycin A1 | Pluracidomycin A1 is a carbapenem antibiotic produced by Str. pluracidomyceticus nov. sp. It has anti-gram-positive bacteria and gram-negative bacteria activity, and has the effect of inhibiting β-lactamase. Synonyms: 1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 7-oxo-3-sulfo-6-(1-(sulfooxy)ethyl)-, (5R-(5alpha,6beta(S*)))-; Pluracidomycin; Pluracidomycin A; SF 2103 A. Grade: >98%. CAS No. 82138-64-5. Molecular formula: 9H11NO10S2. Mole weight: 357.31. | |
| Pluracidomycin B | Pluracidomycin B is a carbapenem antibiotic produced by Str. pluracidomyceticus nov. sp. It has anti-gram-positive bacteria and gram-negative bacteria activity, and has the effect of inhibiting β-lactamase. CAS No. 82138-65-6. Molecular formula: C11H13NO10S2. Mole weight: 383.35. | |
| Pluracidomycin C1 | Pluracidomycin C1 is a carbapenem antibiotic produced by Str. pluracidomyceticus nov. sp. It has anti-gram-positive bacteria and gram-negative bacteria activity, and has the effect of inhibiting β-lactamase. Synonyms: Pluracidomycin C. CAS No. 82138-66-7. Molecular formula: C10H13NO10S2. Mole weight: 371.34. | |
| Pluraflavin A | Pluraflavin A is an antitumor antibiotic produced by Saccharothrix sp. DSM 12931. Pluraflavin A has the effect of inhibiting the transcription of glucose-6-phosphatase gene and has good anti-proliferation activity on tumor cells. Molecular formula: C43H54N2O14. Mole weight: 822.89. | |
| Pluraflavin C | Pluraflavin C is an antitumor antibiotic produced by Saccharothrix sp. DSM 12931. It has good anti-proliferation activity on tumor cells. Molecular formula: C43H56N2O15. Mole weight: 840.91. | |
| Pluraflavin E | Pluraflavin E is an antitumor antibiotic produced by Saccharothrix sp. DSM 12931. It has good anti-proliferation activity on tumor cells. Molecular formula: C36H41NO14. Mole weight: 711.71. | |
| Pluripotin | Pluripotin is a dual inhibitor of ERK1 and RasGAP with K D s of 98 nM and 212 nM, respectively. Pluripotin also inhibits RSK1 , RSK2 , RSK3 , and RSK4 with IC 50 s of 0.5, 2.5, 3.3, and 10.0 μM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SC1. CAS No. 839707-37-8. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10579. | |
| Pluripotin | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Pluripotin | Pluripotin is a dual inhibitor of extracellular signal-regulated kinase 1 (ERK1, MAPK3) and RasGAP. Pluripotin has been shown to maintain embryonic stem cell (ESC) self-renewal. When combined with leukemia inhibitory factor, Pluripotin greatly promotes derivation of embryonic stem cell lines from refractory strains. Group: Biochemicals. Alternative Names: N-[3-[7-[ (1, 3-Dimethyl-1H-pyrazol-5-yl) amino]-1, 4-dihydro-1-methyl-2-oxopyrimido[4, 5-d]pyrimidin-3 (2H) -yl]-4-methylphenyl]-3- (trifluoromethyl) benzamide; N-[3-[7- (2, 5-Dimethyl-2H-pyrazol-3-ylamino) -1-methyl-2-oxo-1, 4-dihydro-2H-pyrimido[4, 5-d]pyrimidin-3-yl]-4-methylphenyl]-3-trifluoromethyl-benzamide; SC 1; Stemolecule SC 1. Grades: Highly Purified. CAS No. 839707-37-8. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| Pluripotin (SC-1, SC1) | Pluripotin (SC-1, SC1). Group: Biochemicals. Alternative Names: N- (3- (7- (1, 3-dimethyl-1H-pyrazol-5-ylamino) -1-methyl-2-oxo-1, 2-dihydropyrimido[4, 5-d]pyrimidin-3 (4H) -yl) -4-methylphenyl) -3- (trifluoromethyl) benzamide. Grades: Highly Purified. CAS No. 839707-37-8. Pack Sizes: 10mg. Molecular Formula: C27H25F3N8O2 , Molecular Weight: 550.5. US Biological Life Sciences. | Worldwide |
| PluriSIn 1 | PluriSIn 1 (NSC 14613) is an inhibitor of stearoyl-coA desaturase (SCD), and is a pluripotent cell-specific inhibitor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NSC 14613. CAS No. 91396-88-2. Pack Sizes: 5 mg; 10 mg; 50 mg. Product ID: HY-15700. | |
| PluriSIn #1 | ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PluriSln 1 (4-Pyridinecarboxylic acid 2-phenylhydrazide) | PluriSln 1 (4-Pyridinecarboxylic acid 2-phenylhydrazide). Group: Biochemicals. Grades: Highly Purified. CAS No. 91396-88-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| PluriSln 1 (NSC 14613, 4-Pyridinecarboxyl icacid, 2-phenylhydrazide) | PluriSln 1 (NSC 14613, 4-Pyridinecarboxyl icacid, 2-phenylhydrazide). Group: Biochemicals. Alternative Names: N'-phenylpyridine-4-carbohydrazide. Grades: Highly Purified. CAS No. 91396-88-2. Pack Sizes: 50mg. Molecular Formula: C12 H11 N3, Molecular Weight: 213.2. US Biological Life Sciences. | Worldwide |
| Pluronic | Pluronic. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Pluronic;Poloxamer;Polyethylene-polypropylene glycol;POP/POE condensate;Synperonic. Product Category: Heterocyclic Organic Compound. CAS No. 9003-11-6. Molecular formula: C5H10O2. Mole weight: HO(C2H4O)a(C3H6O)b(C2H4O)aH. Product ID: ACM2594628. Alfa Chemistry ISO 9001:2015 Certified. | |
| Pluronic F-127 | Pluronic F-127 is a nonionic, surfactant polyol (molecular weight approximately 12,500 daltons) that has been found to facilitate the solubilization of water-insoluble dyes and other materials in physiological media. Group: Biochemicals. Alternative Names: Poloxamer 407. Grades: Cell Culture Grade. CAS No. 9003-11-6. Pack Sizes: 250g, 500g, 1Kg. Molecular Formula: (C3H6O·C2H4O)x, Molecular Weight: Polymer. US Biological Life Sciences. | Worldwide |
| Pluronic F-127 | 100g Pack Size. Group: Detergents. Formula: (C3H6O ·C2H4O)x. CAS No. 9003-11-6. Prepack ID 90030405-100g. Molecular Weight 304.29. See USA prepack pricing. |  |
| Pluronic F-127, 20% DMSO | Pluronic F-127 in DMSO is a nonionic, surfactant polyol (molecular weight approximately 12,500 daltons) that has been found to facilitate the solubilization of water-insoluble dyes and other materials in physiological media. Pluronic F-127 is commonly used to help disperse the acetoxymethyl (AM) esters of our ion indicators as well as our cell tracer dyes such as CFDA-SE.Pluronic F-127 (Poloxamer 407) is a hydrophilic non-ionic surfactant of the more general class of copolymers known as poloxamers. Poloxamer 407 is a triblock copolymer consisting of a central hydrophobic block of polypropylene glycol flanked by two hydrophilic blocks of polyethylene glycol. The approximate lengths of the two PEG blocks is 101 repeat units while the approximate length of the propylene gycol block is 56 repeat units. Group: Biochemicals. Alternative Names: Poloxamer 407; Synperonic PE/F 127. Grades: Purified. CAS No. 9003-11-6. Pack Sizes: 10ml, 25ml, 50ml. Molecular Formula: (C3H6O·C2H4O)x. US Biological Life Sciences. | Worldwide |
| Pluronic F-68 | 500g Pack Size. Group: Analytical Reagents, Biochemicals, Building Blocks, Diagnostic Raw Materials. Formula: (C3H6OC2H4O)x. CAS No. 9003-11-6. Prepack ID 89483155-500g. See USA prepack pricing. | |
| Pluronic® F-68 (PE 6800) | Cell membrane stabilizer; anti-foaming agent. Pluronic® PE 6800 is a low-foaming, nonionic surfactant. It is a block copolymer in which the central polypropylene glycol group is flanked by two polyethylene glycol groups. Group: Biochemicals. Alternative Names: F68; Poloxamer 188; Polyoxyethylene-polyoxypropylene block copolymer; Pluronic PE 6800. Grades: Highly Purified. CAS No. 9003-11-6. Pack Sizes: 250g, 500g, 1Kg. Molecular Formula: (C3H6O.C2H4O)x. US Biological Life Sciences. | Worldwide |
| Pluronic P-105 | Pluronic P105 is a difunctional block copolymer surfactant terminating in primary hydroxyl groups. A nonionic surfactant that is 100% active and relatively nontoxic. Group: Biochemicals. Alternative Names: P105, Polyoxypropylene-polyoxyethylene Block Copolymer, Methyl-oxirane polymer with oxirane. Grades: Purified. CAS No. 9003-11-6. Pack Sizes: 10g, 25g, 100g, 500g. US Biological Life Sciences. | Worldwide |
| plus-end-directed kinesin ATPase | Microtubular motor protein, involved in organelle movement, in mitosis and meiosis. In contrast to dynein, it moves along microtubules towards the plus end. Composed of two heavy (α) chains (110 kDa) and two or more light (β) chains (65-75 kDa). Also hydrolyses GTP. Group: Enzymes. Synonyms: kinesin. Enzyme Commission Number: EC 3.6.4.4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4706; plus-end-directed kinesin ATPase; EC 3.6.4.4; kinesin. Cat No: EXWM-4706. |  |
| Pluviatolide | Pluviatolide is a butyrolactone lignan first isolated from the Australian native plant, Zanthoxylum pluviatile. It has a variety of biological activities, including antioxidant, enzyme inhibitory effect and antispasmodic properties. Synonyms: (-)-Pluviatolide; 2(3H)-Furanone, 4-(1,3-benzodioxol-5-ylmethyl)dihydro-3-((4-hydroxy-3-methoxyphenyl)methyl)-, (3R-trans)-; 3α-(4-Hydroxy-3-methoxybenzyl)-4β-(1,3-benzodioxole-5-ylmethyl)-4,5-dihydrofuran-2(3H)-one; 4,5-Dihydro-4β-[(1,3-benzodioxole-5-yl)methyl]-3α-(4-hydroxy-3-methoxybenzyl)furan-2(3H)-one; trans-Pluviatolide; (3R,4R)-4-(benzo[d][1,3]dioxol-5-ylmethyl)-3-(4-hydroxy-3-methoxybenzyl)dihydrofuran-2(3H)-one. Grade: ≥95% by HPLC. CAS No. 28115-68-6. Molecular formula: C20H20O6. Mole weight: 356.37. | |
| PLX-3618 | PLX-3618 is a molecular glue, that degrades BRD4 with DC50 of 12.2 nM. PLX-3618 promotes polyubiquitination and subsequent proteasomal degradation of BRD4 by recruiting of the E3 ligase substrate receptor, DCAF11. PLX-3618 inhibits the proliferation of various cancer cells, induces apoptosis in AML cells. PLX-3618 exhibits antitumor activity against AML in mouse models[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2851986-76-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-161779. | |
| PLX4032 (Vemurafenib) | Vemurafenib selective BRAFV600E kinase inhibitor; an antitumor agent. Vemurafenib functions by inhibiting the proliferation and mitogen-activated protein/extracellular signal-regulated kinase (ERK) kinase and ERK phosphorylation in a panel of tumor cell lines, including melanoma cell lines expressing BRAFV600E or other mutant BRAF proteins altered at codon 600. Group: Biochemicals. Alternative Names: N-[3-[[5-(4-Chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide; PLX4032; RG7204; RO51-85426; Zelboraf. Grades: Highly Purified. CAS No. 918504-65-1. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. US Biological Life Sciences. | Worldwide |
| PLX4720 | Potent and selective cell permeable B-Raf (V600E) and c-Raf-1 (Y340D/Y341D) inhibitor. Antitumor compound. ERK phosphorylation is potently inhibited exclusive in B-Raf(V600E)-bearing tumor cell lines. Group: Biochemicals. Alternative Names: N-(3-(5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide, Raf Kinase Inhibitor V. Grades: Highly Purified. CAS No. 918505-84-7. Pack Sizes: 5mg, 25mg. Molecular Formula: C??H??ClF?N?O?S. US Biological Life Sciences. | Worldwide |
| PLX-4720 | PLX-4720 is a potent and selective inhibitor of B-RafV600E with IC50 of 13 nM in a cell-free assay, equally potent to c-Raf-1(Y340D and Y341D mutations), and 10-fold selectivity for B-RafV600E than wild-type B-Raf. Uses: Scientific research. Group: Signaling pathways. CAS No. 918505-84-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-51424. | |
| PLX51107 | PLX51107 is a potent and selective BET inhibitor, with Kds of 1.6, 2.1, 1.7, and 5 nM for BD1 and 5.9, 6.2, 6.1, and 120 nM for BD2 of BRD2, BRD3, BRD4, and BRDT, respectively; PLX51107 also interacts with the bromodomains of CBP and EP300 (Kd, in the 100 nM range). Uses: Scientific research. Group: Signaling pathways. CAS No. 1627929-55-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111422. | |
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