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| Product | Description | |
|---|---|---|
| S-Methyl-L-cysteine | S-Methyl-L-cysteine is a natural product that acts as a substrate in the catalytic antioxidant system mediated by methionine sulfoxide reductase A (MSRA), with antioxidative, neuroprotective, and anti-obesity activities. Uses: Scientific research. Group: Natural products. Alternative Names: L-S-Methylcysteine. CAS No. 1187-84-4. Pack Sizes: 10 mM * 1 mL; 1 g. Product ID: HY-B2188. |  |
| S-Methyl-L-cysteine | S-Methyl-L-cysteine, a theurapeutic for neurodegenerative diseases, is a substrate in the catalytic antioxidant system mediated by methionine sulfoxide reductase A (MSRA), with antioxidative, neuroprotective, and anti-obesity activities. Synonyms: S-Methyl-L-cysteine; NSC 15387; NSC15387; NSC-15387; (2R)-2-amino-3-methylsulfanylpropanoic acid; S-11C-methyl-L-cysteine; S-methylcysteine; S-methylcysteine, (DL-Cys)-isomer; S-methylcysteine, (L-Cys)-isomer; S-methylcysteine, hydrochloride, (L-Cys)-isomer. Grades: 98%. CAS No. 1187-84-4. Molecular formula: C4H9NO2S. Mole weight: 135.18. |  |
| S-Methyl-L-cysteine-d3 | S-Methyl-L-cysteine-d3. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| S-Methyl-L-Cysteine-S-oxide | S-Methyl-L-Cysteine-S-oxide is an alliin analogue. Synonyms: 2-Amino-3-methylsulfinylpropanoic acid. Grades: > 95%. CAS No. 6853-87-8. Molecular formula: C4H9NO3S. Mole weight: 151.19. | |
| S-Methyl-L-thiocitrulline acetate | S-Methyl-L-thiocitrulline is a potent nitric oxide synthase (NOS) inhibitor with selectivity for neuronal isoform versus eNOS and iNOS (Ki = 1.2, 11, and 40 nM for nNOS, eNOS, and iNOS, respectively). Synonyms: H-ThioCit(S-Me)-OH AcOH; L-Ornithine, N5-[imino(methylthio)methyl]-, acetate (1:1); L-Ornithine, N5-[imino(methylthio)methyl]-, monoacetate; (S)-2-Amino-5- ( (imino (methylthio)methyl)amino)pentanoic acid acetate. Grades: ≥95%. CAS No. 174063-92-4. Molecular formula: C9H19N3O4S. Mole weight: 265.33. | |
| S-Methyl-L-thiocitrulline acetate salt | ?98% (TLC). Group: Fluorescence/luminescence spectroscopy. |  |
| S-Methyl-L-thiocitrulline dihydrochloride | S-Methyl-L-thiocitrulline is a new potent nitric oxide synthase inhibitor for treatment of cancer. Group: Biochemicals. Grades: Highly Purified. CAS No. 156719-39-0. Pack Sizes: 10mg, 25mg, 100mg, 250mg. Molecular Formula: C7H15N3O2S HCl. US Biological Life Sciences. | Worldwide |
| S-Methyl-L-thiocitrulline, Dihydrochloride - CAS 209589-59-3 | A cell-permeable inhibitor of nitric oxide synthase that exhibits about 17-fold greater selectivity for rat neuronal nitric oxide synthase (IC?? = 300 nM) compared to the endothelial enzyme (IC?? = 5.4 μM). Group: Fluorescence/luminescence spectroscopy. | |
| S-methyl-L-thiocitrulline hydrochloride | Cas No. 209589-59-3. | |
| S-Methyl methanethiosulfonate | analytical standard. Group: Flavor and fragrance standards. | |
| S-Methyl N, N-Diethyldithiocarbamate | S-Methyl N,N-diethyldithiocarbamate (MeDDC) is a metabolite of the alcohol deterrent disulfiram. Uses: Enzyme inhibitors. Synonyms: N,N-Diethylcarbamodithioic Acid Methyl Ester; Diethyldithiocarbamic Acid Methyl Ester. Grades: > 95%. CAS No. 686-07-7. Molecular formula: C6H13NS2. Mole weight: 163.31. | |
| s-Methyl-N,N-diethyldithiocarbamate sulfoxide | s-Methyl-N,N-diethyldithiocarbamate sulfoxide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N,N-Diethyl-1-(methylsulfinyl)methanethioamide. Product Category: Heterocyclic Organic Compound. CAS No. 145195-14-8. Molecular formula: C6H13NOS2. Mole weight: 179.3. Product ID: ACM145195148. Alfa Chemistry ISO 9001:2015 Certified. |  |
| S-Methyl-N,N-diethyldithiocarbamate sulfoxide | S-Methyl-N,N-diethyldithiocarbamate sulfoxide. Group: Biochemicals. Alternative Names: N, N-Diethyl-1- (methylsulfinyl) methanethioamide. Grades: Highly Purified. CAS No. 145195-14-8. Pack Sizes: 50mg. Molecular Formula: C6H13NOS2. US Biological Life Sciences. | Worldwide |
| S-Methyl-N,N-diethylthiocarbamate | S-Methyl-N,N-diethylthiocarbamate. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| S-Methyl-N,N-diethylthiocarbamate Sulfone | A dioxygenated metabolite of Disulfiram (Antabuse) capable of in vitro inactivation of liver mitochondrial aldehyde dehydrogenase (EC 1.2.1.3, ALDH) with higher reactivity than the monooxygenated sulfoxide. Group: Biochemicals. Alternative Names: N, N-Diethyl-1- (methylsulfonyl) formamide. Grades: Highly Purified. CAS No. 155514-79-7. Pack Sizes: 5mg, 10mg, 25mg. US Biological Life Sciences. | Worldwide |
| S-Methyl-N,N-diethylthiocarbamate Sulfoxide | An oxygenated metabolite of Disulfiram (Antabuse) that is capable of in vitro inactivation of liver mitochondrial aldehyde dehydrogenase (EC 1.2.1.3, ALDH). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| S-methyl-penicillamine | An impurity of Penicillamine which is used to treat rheumatoid arthritis, Wilson's disease and a certain disorder which causes kidney stones (cystinuria). Grades: > 95%. Molecular formula: C6H13NO2S. Mole weight: 163.24. | |
| s-Methyl thiohexanoate | s-Methyl thiohexanoate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: S-Methyl hexanethioate;S-(METHYLTHIO)HEXANOATE;METHYL THIOHEXANOATE;METHANETHIOL CAPROATE;FEMA 3862;Hexanethioic acid S-methyl ester. Product Category: Heterocyclic Organic Compound. CAS No. 2432-77-1. Molecular formula: C7H14OS. Mole weight: 146.25. Product ID: ACM2432771. Alfa Chemistry ISO 9001:2015 Certified. | |
| S-Methyl Tiopronin | A metabolite of Tiopronin. Group: Biochemicals. Alternative Names: N-[2-(Methylthio)-1-oxopropyl]glycine. Grades: Highly Purified. CAS No. 87254-91-9. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| S-Methyl Tiopronin | S-Methyl Tiopronin is a metabolite of Tiopronin, which is used as an antidote against heavy metal poisoning. Uses: A metabolite of tiopronin. Synonyms: S-Methylthiola; S-Methylmercaptopropionylglycine; N-[2-(Methylthio)-1-oxopropyl]glycine; Rac-S-Methyl Tiopronin; N-[2-(Methylsulfanyl)propanoyl]glycine; Tiopronin S-Methyl Impurity; Glycine, N-[2-(methylthio)-1-oxopropyl]-. Grades: 95%. CAS No. 87254-91-9. Molecular formula: C6H11NO3S. Mole weight: 177.22. | |
| S-Metolachlor Metabolite CGA 357704 | analytical standard. Group: Pesticides & metabolites standards. | |
| S-Metolachlor Metabolite CGA 368208 | analytical standard. Group: Pesticides & metabolites standards. | |
| S-Metolachlor Metabolite CGA 368208 | Synonyms: Sodium [(2-ethyl-6-me- thylphenyl) carbamoyl] methane sulfonate. CAS No. 1173021-76-5. Mole weight: 279.29. | |
| S-Metolachlor Metabolite CGA 37735 | analytical standard. Group: Pesticides & metabolites standards. | |
| s-Metolachlor metabolite cga 50720 | s-Metolachlor metabolite cga 50720. Uses: Designed for use in research and industrial production. Additional or Alternative Names: S-Metolachlor Metabolite CGA 50720, 152019-74-4, CTK8E7572, AKOS009481030, N-(2-Ethyl-6-methylphenyl)-oxalamic acid, [(2-Ethyl-6-methylphenyl)amino]oxo-acetic acid. Product Category: Heterocyclic Organic Compound. CAS No. 152019-74-4. Molecular formula: C11H13NO3. Mole weight: 207.23. Purity: 0.96. IUPACName: 2-(2-ethyl-6-methylanilino)-2-oxoacetic acid. Canonical SMILES: CCC1=CC=CC(=C1NC(=O)C(=O)O)C. Product ID: ACM152019744. Alfa Chemistry ISO 9001:2015 Certified. | |
| S-Metolachlor Metabolite CGA 50720 | Synonyms: N-(2-Ethyl-6-methyl phenyl) oxamic acid. CAS No. 152019-74-4. Molecular formula: C11H13NO3. Mole weight: 207.23. | |
| S-Metolachlor Metabolite CGA 50720 | analytical standard. Group: Pesticides & metabolites standards. | |
| S-(+)-Mexiletine hydrochloride | S-(+)-Mexiletine hydrochloride. Group: Biochemicals. Alternative Names: (2S)-1-(2,6-Dimethylphenoxy)-2-propanamine hydrochloride; (+)-(S)-Mexiletine hydrochloride; (+)-Mexiletine hydrochloride. Grades: Highly Purified. CAS No. 81771-85-9. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C11H18ClNO. US Biological Life Sciences. | Worldwide |
| SMF | SMF. Group: Polymers. |  |
| SMI-16a | SMI-16a, a cell-permeable thiazolidinedione compound, is a selective and ATP-competitive Pim kinase inhibitor with IC50 values of 0.15, 0.02 and 48 μM for Pim1, Pim2 and PC3 cells, respectively. Synonyms: Pim1/2 Inhibitor IV; PIM1/2 Kinase Inhibitor VI; Pim1/2 Kinase Inhibitor IV; SMI-16a. (5Z)-5-[(4-propoxyphenyl)methylidene]-1,3-thiazolidine-2,4-dione; ST50842732; (Z)-5-(4-Propoxybenzylidene)thiazolidine-2,4-dione; 5-[(4-Propyloxyphenyl)methylene] 2,4-thiazolidinedione; (5Z)-5-(4-propoxybenzylidene)-1,3-thiazolidine-2,4-dione. CAS No. 587852-28-6. Molecular formula: C13H13NO3S. Mole weight: 263.31. | |
| SMI481 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SMI 481 | SMI 481 is a small-molecule inhibitor (SMI) of the yeast phosphatidylinositol transfer proteins (PITP) Sec14 (IC50 values of 211 nM and 2.87 μM for Sec14 mediated [3H]PtdIns transfer in vitro, and Sec14 dependent cell growth inhibition of WT (CTY182, gray) strains, respectively). SMI 481 exhibits exquisite pathway selectivity in inhibiting phosphoinositide signaling in cells with >200-fold selectivity over other yeast Sec14-like transfer activities. Synonyms: SMI481; SMI-481 SMI 481; NPPM 6748-481; NPPM 6748481; NPPM6748481; NPPM-6748-481; (4-Chloro-3-nitrophenyl)(4-(2-fluorophenyl)piperazin-1-yl)methanone; 1-(4-chloro-3-nitrobenzoyl)-4-(2-fluorophenyl)piperazine; (4-chloro-3-nitrophenyl)[4-(2-fluorophenyl)piperazin-1-yl]methanone. Grades: 99%. CAS No. 432020-20-7. Molecular formula: C17H15ClFN3O3. Mole weight: 363.77. | |
| SMI-4a | SMI-4a, also called as TCS-PIM-1-4a, a thiazolidinedione compound, is a potent, selective ATP-competitive inhibitor against Pim protein kinase (IC50 = 24 nM against Pim-1 and 100 nM against Pim-2) with little or no activity against a panel of 58 other kin. Synonyms: SMI-4a; SMI 4a; SMI4a; (5E)-5-[[3-(trifluoromethyl)phenyl]methylidene]-1,3-thiazolidine-2,4-dioneTCS-PIM-1-4aMS-1740; MS 1740; MS1740327033-36-35-{[3-(trifluoromethyl)phenyl]methylidene}-1,3-thiazolidine-2,4-dione. CAS No. 327033-36-3. Molecular formula: C11H6F3NO2S. Mole weight: 273.20. | |
| SMI-4a | Selective inhibitor of Pim-1 and Pim-2 protein kinases. Inducer of G1 phase cell cycle arrest. Inducer of p27Kip1. Inducer of apoptosis through the mitochondrial pathway. Inhibitor of the mammalian target of rapamycin C1 (mTORC1) pathway. Downregulates c-myc. Inhibitor of PRAS40 phosphorylation and mTOR activity. Potential anti-cancer compound. Blocks prostate cancer growth. Group: Biochemicals. Grades: Highly Purified. CAS No. 327033-36-3. Pack Sizes: 5mg. Molecular Formula: C11H6F3NO2S, Method for Determining. US Biological Life Sciences. | Worldwide |
| SMI-4a | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SMI-4a (5E/Z) -[[3- (Trifluoromethyl) phenyl]methylene]-2, 4-thiazolidinedione) | A selective, ATP-competitive inhibitor Pim-1 (IC50=21nm) and Pim-2 (IC50=100nm) protein kinases. Blocks mTORC1 activity via activation of AMPK. SMI-4a has been found to inhibit prostate cancer cell growth and induce G1 phase cell-cycle arrest in precursor T-cell lymphoblastic leukemia/lymphoma cell lines. Group: Biochemicals. Grades: Highly Purified. CAS No. 327033-36-3. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| SMIFH2 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SMIFH2 | SMIFH2 is a formin specific inhibitor. SMIFH2 inhibits actin polymerization by Formins and affects the actin cytoskeleton. Uses: Designed for use in research and industrial production. Additional or Alternative Names: STK197413, ZINC01203437, SMIFH2, AC1M4GYW, MolPort-002-178-894, (5E)-1-(3-bromophenyl)-5-(furan-2-ylmethylidene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione, AKOS001651888, BIM-0040107.P001, (5E)-1-(3-bromophenyl)-5-(furan-2-ylmethylidene)-2-sulfanylidene-1,3-diazinane-4,6-dione, 1-(3-Bromophenyl)-5-(2-furanylmethylene)dihydro-2-thioxo-4,6(1H,5H)-pyrimidinedione, 340316-62-3. Product Category: Inhibitors. Appearance: Solid. CAS No. 340316-62-3. Molecular formula: C15H9BrN2O3S. Mole weight: 377.21. Purity: 0.96. IUPACName: (5E)-1-(3-bromophenyl)-5-(furan-2-ylmethylidene)-2-sulfanylidene-1,3-diazinane-4,6-dione. Canonical SMILES: C1=CC(=CC(=C1)Br)N2C(=O)C(=CC3=CC=CO3)C(=O)NC2=S. Product ID: ACM340316623. Alfa Chemistry ISO 9001:2015 Certified. | |
| SMIFH2 | SMIFH2. Group: Biochemicals. Grades: Purified. CAS No. 340316-62-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SMIFH2 | SMIFH2 is an inhibitor of formin homology 2 (FH2) domains. SMIFH2 prevents formin-mediated actin nucleation and barbed end elongation, disrupts formin-dependent actin cytoskeletal structures in fission yeast and mammalian NIH 3T3 fibroblasts. Synonyms: SMIFH-2; SMIFH 2; SMIFH2; 1-(3-Bromophenyl)-5-(2-furanylmethylene)dihydro-2-thioxo-4,6(1H,5H)-pyrimidinedione; (5E)-1-(3-bromophenyl)-5-(furan-2-ylmethylidene)-2-sulfanylidene-1,3-diazinane-4,6-dione. Grades: ≥99% by HPLC. CAS No. 340316-62-3. Molecular formula: C15H9BrN2O3S. Mole weight: 377.21. | |
| Smi I | One unit of the enzyme is the amount required to hydrolyze 1 μg of T7 DNA (SspI-digest) in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 20-fold overdigestion with enzyme >95% of the dna fragments can be ligated and recut. ligation >95% in presence of 10% peg. Group: Restriction Enzymes. Purity: 1000U; 5000U. ATTT↑AAAT TAAA↓TTTA. Activity: 20000u.a./ml. Appearance: 10 X SE-buffer O, BSA. Storage: -20°C. Form: Liquid. Source: Streptococcus milleri S. Pack: 10 mM Tris-HCl (pH 7.5); 250 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 100 μg/ml BSA; 50% glycerol. Cat No: ET-1177RE. |  |
| Smilagenin | Smilagenin. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (25R)-SPIROSTAN-3BETA-OL; 25R,5BETA-SPIROSTAN-3BETA-OL; ISOSARSAPOGENIN; (25R)-Spirostan-3.β.-ol; (25R)-5beta-spirostan-3beta-ol; ISOSARSAPOGENINE; ESMILAGENIN; SMILAGENIN; ISOSARSASAPOGENIN. Product Category: Steroidal Compounds. CAS No. 126-18-1. Molecular formula: C27H44O3. Mole weight: 416.64. Purity: 0.98. IUPACName: (25R)-5β-spirostan-3β-ol. Canonical SMILES: CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)OC1. Density: 1.11g/cm³. ECNumber: 204-775-8. Product ID: ACM126181. Alfa Chemistry ISO 9001:2015 Certified. | |
| Smilagenin | Smilagenin (SMI) is a small-molecule steroidal sapogenin from Anemarrhena asphodeloides and Pelargonium hortorum widely used in traditional Chinese medicine for treating chronic neurodegeneration diseases [1]. Smilagenin (SMI) improves memory of aged rats by increasing the muscarinic receptor subtype 1 (M1)-receptor density [2]. Smilagenin (SMI) attenuates Aβ(25-35)-induced neurodegenerationvia stimulating the gene expression of brain-derived neurotrophic factor, may represents a novel therapeutic strategy for AD [3]. Uses: Scientific research. Group: Natural products. CAS No. 126-18-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106353. | |
| Smilagenin acetate | Smilagenin acetate is a sapogenin derivative extracted from patent US20030004147A1. Smilagenin acetate increases the expression of acetylcholine m2 receptors and can be used for the research of dementia [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 4947-75-5. Pack Sizes: 5 mg. Product ID: HY-N7421. | |
| Smilax sarsaparilla, ext. | Smilax sarsaparilla, ext. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Smilax sarsaparilla, ext.;SARSAPARILLA ROOT EXTRACT. Product Category: Heterocyclic Organic Compound. CAS No. 91770-66-0. Purity: 0.96. Product ID: ACM91770660. Alfa Chemistry ISO 9001:2015 Certified. | |
| SmiM I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 500 U; 2500U. CAYNN↑NNRTG GTRNN↓NNYAC. Activity: 5000u.a./ml. Appearance: 10 X SE-buffer W. Storage: -20°C. Form: Liquid. Source: Sphingobacterium mizutae M. Pack: 10 mM Tris-HCl (pH 7.5); 250 mM NaCl; 0,1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; and 50% glycerol. Cat No: ET-1178RE. | |
| SMIP004 | SMIP004 a novel inducer of cancer-cell selective apoptosis of human prostate cancer cells, at low micromolar concentration it upregulated p27 in various prostate cancer cell lines. MTT assay in LNCaP-S14 cells: IC50=1.09 uM. Synonyms: N-(4-butyl-2-methylphenyl)acetamide143360-00-3N1-(4-butyl-2-methylphenyl)acetamideSMIP004; SMIP-004; SMIP 004. Acetamide , N- (4-butyl-2- methyl phenyl) -2- methyl -4-butylacetanilide N- (4-butyl-2- methyl phenyl) acetamide ZINC02565087Maybridge1_000068ACMC-1C0QFAC1MCN19MixCom1_0. CAS No. 143360-00-3. Molecular formula: C13H19NO. Mole weight: 205.15. | |
| S-Mirtazapine | S-Mirtazapine is an enantiomer of Mirtazapine, an antidepressant. R-Mirtazapine showed antinociceptive effects in acute thermal nociception, whereas S-Mirtazapine showed pronociceptive effects. Uses: Anti-anxiety agents. Synonyms: (S)-Org 3770; Esmirtazapine; Org 44-20; S-(+)-Mirtazapine; (S)-1,2,3,4,10,14b-Hexahydro-2-methyl-pyrazino[2,1-a]pyrido[2,3-c][2]benzazepine; (+)-Mirtazapine; (14bS)-1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepine ; (S)-6-Azamian. Grades: > 95%. CAS No. 61337-87-9. Molecular formula: C17H19N3. Mole weight: 265.35. | |
| SMK-17 | SMK-17 is a MEK1/2 inhibitor. It can inhibit MEK1 kinase activity in a non-ATP-competitive manner and it is highly selective to MEK1 and 2. SMK-17 can inhibit the growth of tumor cell lines in vitro. But it did not inhibit the phosphorylation of ERK5. SMK-17 selectively blocked the MAPK pathway signaling without affecting other signal pathways, which resulted in significant antitumor efficacy without notable side effects. Uses: Antitumor. Synonyms: SMK17; SMK 17; SMK17; N-(2-((2-chloro-4-iodophenyl)amino)-3,4-difluorophenyl)-4-(isopropylamino)piperidine-1-sulfonamide. Grades: 98%. CAS No. 765958-29-0. Molecular formula: C20H24ClF2IN4O2S. Mole weight: 584.85. | |
| SMND-309 | SMND-309 is a novel derivative of salvianolic acid B, and has shown protective effects against rat cortical neuron damage in vitro and in vivo. Synonyms: SMND-309; SMND 309; SMND309. Grades: >98%. CAS No. 1065559-56-9. Molecular formula: C18H14O8. Mole weight: 358.3. | |
| Smo Antagonist, SA10 (4- ( (Benzo [c] [1, 2, 5] thiadiazole-4-sulfonamido) methyl -N- (3-phenylpropyl ) cyclohexane carboxamide) | SA10 inhibits SAG (Smoothened agonist) activation of Hh signaling in Shh-LIGHT 2 cells (IC50 = 5uM). However, unlike SA1 and SA9, Smo antagonist SA10 does not directly bind to Smo. Inhibits the localization o Smo to cilia. Also treatment of Ptch1-/- MEFs with SA10 suppresses the beta-galactosidase activity (IC50 = 11.0uM) and inhibits the expression of Gli1 and Ptch1 in ASZ1 cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2mg, 5mg. US Biological Life Sciences. | Worldwide |
| Smo Antagonist, SA1 (3-(3-(4-Fluorophenyl)-2, 5, 7-trimethylpyrazolo[1, 5a]pyrimidin-6-yl)-N-(4-(furan-2-yl)butan-2-yl)propanamide) | A Smoothened (Smo) antagonist. SA1 inhibits Hh pathway by interacting directly with Smo. Inhibits SAG (Smoothened agonist) activation of Hh signaling in Shh-LIGHT 2 cells (IC50 = 3.1uM). Also inhibits the localization of Smo to cilia. Treatment of Ptch1-/- MEFs with SA1 suppresses the b-galactosidase activity (IC50 = 3.8uM) and inhibits the expression of Gli1 and Ptch1 in ASZ1 cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2mg, 5mg. US Biological Life Sciences. | Worldwide |
| Smo Antagonist, SA9 (3- (3- (4-Fluorophenyl) -5-oxo-4, 5-dihydro-[1, 2, 4]triazolo[4, 3-a]quinazolin-1-yl-N- (3-methylphenethyl) propanamide) | SA9 inhibits Hh pathway by interacting directly with Smo. It inhibits SAG (Smoothened agonist) activation of Hh signaling in Shh-LIGHT 2 cells (IC50 =19um). Induces the localization of Smo to cilia in ASZ1 cells, but not in IMCD3 cells. Also treatment of Ptch1-/- MEFs with SA9 suppresses the b-galactosidase activity (IC50 =1.0um) and inhibits the expression of Gli1 and Ptch1 in ASZ1 cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2mg, 5mg. US Biological Life Sciences. | Worldwide |
| SMO-IN-2 | SMO-IN-2 (compound 1) is a potent smoothened (SMO) inhibitor with an IC 50 value of 123.4 nM for hedgehog (Hh) signaling pathway. SMO-IN-2 has antiproliferative activity against human medulloblastoma cell line Daoy. Anticancer activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1822355-27-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-150564. | |
| Smoke Point Standard | ASTM D 1322 / IP 57, 24.25 mm. Group: Cloud point standards. | |
| Smoke Tree Extract (Ratio) | Smoke Tree Extract (Ratio). Group: Others. Purity: 4:1~20:1. Smoke Tree Extract (Ratio). Cat No: EXTW-051. | |
| Smoothened Agonist, SAG - CAS 364590-63-6 | A cell-permeable Smoothened Agonist, SAG, CAS 364590-63-6, modulates the coupling of Smo with its downstream effector by interacting with the Smo heptahelical domain (KD = 59 nM). Group: Fluorescence/luminescence spectroscopy. | |
| Smoothened Agonist, SAG (N-Methyl-N- (3-pyridinylbenzyl) -N- (3-chlorobenzo [b]thiophene-2-carbonyl) -1, 4-diaminocyclohexane, SAG1.3 ) | A cell-permeable benzothiophene compound that modulates the coupling of Smo with its downstream effector by interacting with the Smo heptahelical domain (=59nM). Shown to induce Smo internalization. Shown to induce Hedgehog pathway activation (EC50= ?3nM in NIH 3T3-derived Shh-LIGHT2 cells) and counteracts Cyclopamine-KAAD inhibition of Smo. Reported to act as an activator at low concentrations and as an inhibitor at very high concentrations. Group: Biochemicals. Grades: Highly Purified. CAS No. 364590-63-6. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| SMPT | SMPT is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 112241-19-7. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-126405. | |
| S-MTC | S-MTC is a selective type I nitric oxide synthase (NOS) inhibitor. Uses: Enzyme inhibitors. Synonyms: L-Ornithine, N5-[imino(methylthio)methyl]-; N5-[Imino(methylthio)methyl]-L-ornithine; (S)-2-Amino-5- ( (imino (methylthio)methyl)amino)pentanoic acid; S-Methyl-L-thiocitrulline; S-Methylthiocitrulline; L-S-Methylthiocitrulline; N(delta)-(S-Methylisothioureido)norvaline. Grades: ≥95%. CAS No. 156719-41-4. Molecular formula: C7H15N3O2S. Mole weight: 205.28. | |
| SMTP-1 | SMTP-1 is a Staplabin homolog isolated from Stachybotrys microspora IFO30018. It enhanced the binding of Plasminogen to Fibrin. Molecular formula: C25H35NO5. Mole weight: 429.5. | |
| SMTP-2 | SMTP-2 is a Staplabin homolog isolated from Stachybotrys microspora IFO30018. It enhanced the binding of Plasminogen to Fibrin. The activity of SMTP-2 is weaker than SMTP-1. Molecular formula: C25H37NO7. Mole weight: 463.6. | |
| SMTP-3 | SMTP-3 is a Staplabin homolog isolated from Stachybotrys microspora IFO30018. It enhanced the binding of Plasminogen to Fibrin. Molecular formula: C26H35NO7. Mole weight: 473.6. | |
| SMTP-4 | SMTP-4 is a Staplabin homolog isolated from Stachybotrys microspora IFO30018. It enhanced the binding of Plasminogen to Fibrin. Molecular formula: C32H39NO6. Mole weight: 533.7. | |
| SMTP-5 | SMTP-5 is a Staplabin homolog isolated from Stachybotrys microspora IFO30018. It enhanced the binding of Plasminogen to Fibrin. Molecular formula: C29H41NO6. Mole weight: 499.6. | |
| SMTP-6 | SMTP-6 is a Staplabin homolog isolated from Stachybotrys microspora IFO30018. It enhanced the binding of Plasminogen to Fibrin. Molecular formula: C34H40N2O6. Mole weight: 572.7. | |
| SMURF1 Active human | recombinant, expressed in baculovirus infected insect cells, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| SMURF2 Active human | recombinant, expressed in baculovirus infected insect cells, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| SMYD2 Active human | recombinant, expressed in baculovirus infected insect cells, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| SMYD2, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
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