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| Product | Description | |
|---|---|---|
| SMI-4a (5E/Z) -[[3- (Trifluoromethyl) phenyl]methylene]-2, 4-thiazolidinedione) | A selective, ATP-competitive inhibitor Pim-1 (IC50=21nm) and Pim-2 (IC50=100nm) protein kinases. Blocks mTORC1 activity via activation of AMPK. SMI-4a has been found to inhibit prostate cancer cell growth and induce G1 phase cell-cycle arrest in precursor T-cell lymphoblastic leukemia/lymphoma cell lines. Group: Biochemicals. Grades: Highly Purified. CAS No. 327033-36-3. Pack Sizes: 5mg. US Biological Life Sciences. |  Worldwide |
| SMIFH2 | SMIFH2. Group: Biochemicals. Grades: Purified. CAS No. 340316-62-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SMIFH2 | SMIFH2 is a formin specific inhibitor. SMIFH2 inhibits actin polymerization by Formins and affects the actin cytoskeleton. Uses: Designed for use in research and industrial production. Additional or Alternative Names: STK197413, ZINC01203437, SMIFH2, AC1M4GYW, MolPort-002-178-894, (5E)-1-(3-bromophenyl)-5-(furan-2-ylmethylidene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione, AKOS001651888, BIM-0040107.P001, (5E)-1-(3-bromophenyl)-5-(furan-2-ylmethylidene)-2-sulfanylidene-1,3-diazinane-4,6-dione, 1-(3-Bromophenyl)-5-(2-furanylmethylene)dihydro-2-thioxo-4,6(1H,5H)-pyrimidinedione, 340316-62-3. Product Category: Inhibitors. Appearance: Solid. CAS No. 340316-62-3. Molecular formula: C15H9BrN2O3S. Mole weight: 377.21. Purity: 0.96. IUPACName: (5E)-1-(3-bromophenyl)-5-(furan-2-ylmethylidene)-2-sulfanylidene-1,3-diazinane-4,6-dione. Canonical SMILES: C1=CC(=CC(=C1)Br)N2C(=O)C(=CC3=CC=CO3)C(=O)NC2=S. Product ID: ACM340316623. Alfa Chemistry ISO 9001:2015 Certified. |  |
| SMIFH2 | SMIFH2 is an inhibitor of formin homology 2 (FH2) domains. SMIFH2 prevents formin-mediated actin nucleation and barbed end elongation, disrupts formin-dependent actin cytoskeletal structures in fission yeast and mammalian NIH 3T3 fibroblasts. Synonyms: SMIFH-2; SMIFH 2; SMIFH2; 1-(3-Bromophenyl)-5-(2-furanylmethylene)dihydro-2-thioxo-4,6(1H,5H)-pyrimidinedione; (5E)-1-(3-bromophenyl)-5-(furan-2-ylmethylidene)-2-sulfanylidene-1,3-diazinane-4,6-dione. Grades: ≥99% by HPLC. CAS No. 340316-62-3. Molecular formula: C15H9BrN2O3S. Mole weight: 377.21. |  |
| Smi I | One unit of the enzyme is the amount required to hydrolyze 1 μg of T7 DNA (SspI-digest) in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 20-fold overdigestion with enzyme >95% of the dna fragments can be ligated and recut. ligation >95% in presence of 10% peg. Group: Restriction Enzymes. Purity: 1000U; 5000U. ATTT↑AAAT TAAA↓TTTA. Activity: 20000u.a./ml. Appearance: 10 X SE-buffer O, BSA. Storage: -20°C. Form: Liquid. Source: Streptococcus milleri S. Pack: 10 mM Tris-HCl (pH 7.5); 250 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 100 μg/ml BSA; 50% glycerol. Cat No: ET-1177RE. |  |
| Smilagenin | Smilagenin (SMI) is a small-molecule steroidal sapogenin from Anemarrhena asphodeloides and Pelargonium hortorum widely used in traditional Chinese medicine for treating chronic neurodegeneration diseases [1]. Smilagenin (SMI) improves memory of aged rats by increasing the muscarinic receptor subtype 1 (M1)-receptor density [2]. Smilagenin (SMI) attenuates Aβ(25-35)-induced neurodegenerationvia stimulating the gene expression of brain-derived neurotrophic factor, may represents a novel therapeutic strategy for AD [3]. Uses: Scientific research. Group: Natural products. CAS No. 126-18-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106353. |  |
| Smilagenin | Smilagenin. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (25R)-SPIROSTAN-3BETA-OL; 25R,5BETA-SPIROSTAN-3BETA-OL; ISOSARSAPOGENIN; (25R)-Spirostan-3.β.-ol; (25R)-5beta-spirostan-3beta-ol; ISOSARSAPOGENINE; ESMILAGENIN; SMILAGENIN; ISOSARSASAPOGENIN. Product Category: Steroidal Compounds. CAS No. 126-18-1. Molecular formula: C27H44O3. Mole weight: 416.64. Purity: 0.98. IUPACName: (25R)-5β-spirostan-3β-ol. Canonical SMILES: CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)OC1. Density: 1.11g/cm³. ECNumber: 204-775-8. Product ID: ACM126181. Alfa Chemistry ISO 9001:2015 Certified. | |
| Smilagenin acetate | Smilagenin acetate is a sapogenin derivative extracted from patent US20030004147A1. Smilagenin acetate increases the expression of acetylcholine m2 receptors and can be used for the research of dementia [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 4947-75-5. Pack Sizes: 5 mg. Product ID: HY-N7421. | |
| Smilax sarsaparilla, ext. | Smilax sarsaparilla, ext. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Smilax sarsaparilla, ext.;SARSAPARILLA ROOT EXTRACT. Product Category: Heterocyclic Organic Compound. CAS No. 91770-66-0. Purity: 0.96. Product ID: ACM91770660. Alfa Chemistry ISO 9001:2015 Certified. | |
| SmiM I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 500 U; 2500U. CAYNN↑NNRTG GTRNN↓NNYAC. Activity: 5000u.a./ml. Appearance: 10 X SE-buffer W. Storage: -20°C. Form: Liquid. Source: Sphingobacterium mizutae M. Pack: 10 mM Tris-HCl (pH 7.5); 250 mM NaCl; 0,1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; and 50% glycerol. Cat No: ET-1178RE. | |
| SMIP004 | SMIP004 a novel inducer of cancer-cell selective apoptosis of human prostate cancer cells, at low micromolar concentration it upregulated p27 in various prostate cancer cell lines. MTT assay in LNCaP-S14 cells: IC50=1.09 uM. Synonyms: N-(4-butyl-2-methylphenyl)acetamide143360-00-3N1-(4-butyl-2-methylphenyl)acetamideSMIP004; SMIP-004; SMIP 004. Acetamide , N- (4-butyl-2- methyl phenyl) -2- methyl -4-butylacetanilide N- (4-butyl-2- methyl phenyl) acetamide ZINC02565087Maybridge1_000068ACMC-1C0QFAC1MCN19MixCom1_0. CAS No. 143360-00-3. Molecular formula: C13H19NO. Mole weight: 205.15. | |
| S-Mirtazapine | S-Mirtazapine is an enantiomer of Mirtazapine, an antidepressant. R-Mirtazapine showed antinociceptive effects in acute thermal nociception, whereas S-Mirtazapine showed pronociceptive effects. Uses: Anti-anxiety agents. Synonyms: (S)-Org 3770; Esmirtazapine; Org 44-20; S-(+)-Mirtazapine; (S)-1,2,3,4,10,14b-Hexahydro-2-methyl-pyrazino[2,1-a]pyrido[2,3-c][2]benzazepine; (+)-Mirtazapine; (14bS)-1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepine ; (S)-6-Azamian. Grades: > 95%. CAS No. 61337-87-9. Molecular formula: C17H19N3. Mole weight: 265.35. | |
| SMK-17 | SMK-17 is a MEK1/2 inhibitor. It can inhibit MEK1 kinase activity in a non-ATP-competitive manner and it is highly selective to MEK1 and 2. SMK-17 can inhibit the growth of tumor cell lines in vitro. But it did not inhibit the phosphorylation of ERK5. SMK-17 selectively blocked the MAPK pathway signaling without affecting other signal pathways, which resulted in significant antitumor efficacy without notable side effects. Uses: Antitumor. Synonyms: SMK17; SMK 17; SMK17; N-(2-((2-chloro-4-iodophenyl)amino)-3,4-difluorophenyl)-4-(isopropylamino)piperidine-1-sulfonamide. Grades: 98%. CAS No. 765958-29-0. Molecular formula: C20H24ClF2IN4O2S. Mole weight: 584.85. | |
| SMND-309 | SMND-309 is a novel derivative of salvianolic acid B, and has shown protective effects against rat cortical neuron damage in vitro and in vivo. Synonyms: SMND-309; SMND 309; SMND309. Grades: >98%. CAS No. 1065559-56-9. Molecular formula: C18H14O8. Mole weight: 358.3. | |
| Smo Antagonist, SA10 (4- ( (Benzo [c] [1, 2, 5] thiadiazole-4-sulfonamido) methyl -N- (3-phenylpropyl ) cyclohexane carboxamide) | SA10 inhibits SAG (Smoothened agonist) activation of Hh signaling in Shh-LIGHT 2 cells (IC50 = 5uM). However, unlike SA1 and SA9, Smo antagonist SA10 does not directly bind to Smo. Inhibits the localization o Smo to cilia. Also treatment of Ptch1-/- MEFs with SA10 suppresses the beta-galactosidase activity (IC50 = 11.0uM) and inhibits the expression of Gli1 and Ptch1 in ASZ1 cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2mg, 5mg. US Biological Life Sciences. | Worldwide |
| Smo Antagonist, SA1 (3-(3-(4-Fluorophenyl)-2, 5, 7-trimethylpyrazolo[1, 5a]pyrimidin-6-yl)-N-(4-(furan-2-yl)butan-2-yl)propanamide) | A Smoothened (Smo) antagonist. SA1 inhibits Hh pathway by interacting directly with Smo. Inhibits SAG (Smoothened agonist) activation of Hh signaling in Shh-LIGHT 2 cells (IC50 = 3.1uM). Also inhibits the localization of Smo to cilia. Treatment of Ptch1-/- MEFs with SA1 suppresses the b-galactosidase activity (IC50 = 3.8uM) and inhibits the expression of Gli1 and Ptch1 in ASZ1 cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2mg, 5mg. US Biological Life Sciences. | Worldwide |
| Smo Antagonist, SA9 (3- (3- (4-Fluorophenyl) -5-oxo-4, 5-dihydro-[1, 2, 4]triazolo[4, 3-a]quinazolin-1-yl-N- (3-methylphenethyl) propanamide) | SA9 inhibits Hh pathway by interacting directly with Smo. It inhibits SAG (Smoothened agonist) activation of Hh signaling in Shh-LIGHT 2 cells (IC50 =19um). Induces the localization of Smo to cilia in ASZ1 cells, but not in IMCD3 cells. Also treatment of Ptch1-/- MEFs with SA9 suppresses the b-galactosidase activity (IC50 =1.0um) and inhibits the expression of Gli1 and Ptch1 in ASZ1 cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2mg, 5mg. US Biological Life Sciences. | Worldwide |
| SMO-IN-2 | SMO-IN-2 (compound 1) is a potent smoothened (SMO) inhibitor with an IC 50 value of 123.4 nM for hedgehog (Hh) signaling pathway. SMO-IN-2 has antiproliferative activity against human medulloblastoma cell line Daoy. Anticancer activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1822355-27-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-150564. | |
| Smoke Tree Extract (Ratio) | Smoke Tree Extract (Ratio). Group: Others. Purity: 4:1~20:1. Smoke Tree Extract (Ratio). Cat No: EXTW-051. | |
| Smoothened Agonist, SAG (N-Methyl-N- (3-pyridinylbenzyl) -N- (3-chlorobenzo [b]thiophene-2-carbonyl) -1, 4-diaminocyclohexane, SAG1.3 ) | A cell-permeable benzothiophene compound that modulates the coupling of Smo with its downstream effector by interacting with the Smo heptahelical domain (=59nM). Shown to induce Smo internalization. Shown to induce Hedgehog pathway activation (EC50= ?3nM in NIH 3T3-derived Shh-LIGHT2 cells) and counteracts Cyclopamine-KAAD inhibition of Smo. Reported to act as an activator at low concentrations and as an inhibitor at very high concentrations. Group: Biochemicals. Grades: Highly Purified. CAS No. 364590-63-6. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| SMPT | SMPT is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 112241-19-7. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-126405. | |
| S-MTC | S-MTC is a selective type I nitric oxide synthase (NOS) inhibitor. Uses: Enzyme inhibitors. Synonyms: L-Ornithine, N5-[imino(methylthio)methyl]-; N5-[Imino(methylthio)methyl]-L-ornithine; (S)-2-Amino-5- ( (imino (methylthio)methyl)amino)pentanoic acid; S-Methyl-L-thiocitrulline; S-Methylthiocitrulline; L-S-Methylthiocitrulline; N(delta)-(S-Methylisothioureido)norvaline. Grades: ≥95%. CAS No. 156719-41-4. Molecular formula: C7H15N3O2S. Mole weight: 205.28. | |
| SMTP-1 | SMTP-1 is a Staplabin homolog isolated from Stachybotrys microspora IFO30018. It enhanced the binding of Plasminogen to Fibrin. Molecular formula: C25H35NO5. Mole weight: 429.5. | |
| SMTP-2 | SMTP-2 is a Staplabin homolog isolated from Stachybotrys microspora IFO30018. It enhanced the binding of Plasminogen to Fibrin. The activity of SMTP-2 is weaker than SMTP-1. Molecular formula: C25H37NO7. Mole weight: 463.6. | |
| SMTP-3 | SMTP-3 is a Staplabin homolog isolated from Stachybotrys microspora IFO30018. It enhanced the binding of Plasminogen to Fibrin. Molecular formula: C26H35NO7. Mole weight: 473.6. | |
| SMTP-4 | SMTP-4 is a Staplabin homolog isolated from Stachybotrys microspora IFO30018. It enhanced the binding of Plasminogen to Fibrin. Molecular formula: C32H39NO6. Mole weight: 533.7. | |
| SMTP-5 | SMTP-5 is a Staplabin homolog isolated from Stachybotrys microspora IFO30018. It enhanced the binding of Plasminogen to Fibrin. Molecular formula: C29H41NO6. Mole weight: 499.6. | |
| SMTP-6 | SMTP-6 is a Staplabin homolog isolated from Stachybotrys microspora IFO30018. It enhanced the binding of Plasminogen to Fibrin. Molecular formula: C34H40N2O6. Mole weight: 572.7. | |
| Smyrindioloside | Smyrindioloside. Group: Biochemicals. Grades: Plant Grade. CAS No. 87592-77-6. Pack Sizes: 5mg. Molecular Formula: C20H24O10, Molecular Weight: 424.4. US Biological Life Sciences. | Worldwide |
| SN 003 | SN 003 is a reversible corticotropin releasing factor receptor 1 (CRF1) antagonist (Ki = 3.4 and 7.9 nM at rat and human CRF1, respectively) that displays >1000-fold selectivity over CRF2 receptors. SN 003 was shown to inhibit CRF-induced ACTH release in vitro (IC50 = 241 nM). Synonyms: SN 003; SN003; SN-003; N-(4-Methoxy-2-methylphenyl)-1-[1-(methoxymethyl)propyl]-6-methyl-1H-1,2,3-triazolo[4,5-c]pyridin-4-amine; 1-(1-methoxybutan-2-yl)-N-(4-methoxy-2-methylphenyl)-6-methyltriazolo[4,5-c]pyridin-4-amine. Grades: ≥98% by HPLC. CAS No. 197801-88-0. Molecular formula: C19H25N5O2. Mole weight: 355.43. | |
| SN 003 | SN 003. Group: Biochemicals. Grades: Purified. CAS No. 197801-88-0. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| SN-008 | SN-008, a less active SN-011 analog, can be used as a negative control [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2249106-01-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145009. | |
| SN-011 | SN-011 is a potent and selective mouse and human STING inhibitor, with an IC 50 of 76 nM for STING signaling. SN-011 competes with cyclic dinucleotide (CDN) for the binding pocket of the STING dimer, blocking CDN binding and STING activation. SN-011 can be used for the research of STING-driven autoimmune and inflammatory disease [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2249435-90-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145010. | |
| sn-1,2-Dioctanoylglycerol (DOG) | Cell permeable lipid shown to mimic the effect of tumor-promoting phorbol diesters on mitogenesis and EGF binding and action in intact cells. Group: Biochemicals. Alternative Names: DOG. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| sn-1 acyl-lipid ω-3 desaturase (ferredoxin) | The enzyme, characterized from cyanobacteria, introduces a cis double bond at carbon 15 of linoleoyl and γ-linolenoyl groups attached to the sn-1 position of glycerolipids. The enzyme is an ω desaturase, and determines the location of the double bond by counting three carbons from the methyl end of the fatty acid. It is nonspecific with respect to the polar head group of the glycerolipid. cf. EC 1.14.19.35, sn-2 acyl-lipid ω-3 desaturase (ferredoxin). Group: Enzymes. Synonyms: desB (gene name). Enzyme Commission Number: EC 1.14.19.36. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1000; sn-1 acyl-lipid ω-3 desaturase (ferredoxin); EC 1.14.19.36; desB (gene name). Cat No: EXWM-1000. | |
| sn-1 linoleoyl-lipid 6-desaturase | The enzyme, characterized from cyanobacteria, introduces a cis double bond at carbon 6 of linoleoyl groups (18:2) attached to the sn-1 position of glycerolipids. The enzyme is a front-end desaturase, introducing the new double bond between a pre-existing double bond and the carboxyl-end of the fatty acid. It is nonspecific with respect to the polar head group of the glycerolipid. Group: Enzymes. Synonyms: desD (gene name). Enzyme Commission Number: EC 1.14.19.46. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1011; sn-1 linoleoyl-lipid 6-desaturase; EC 1.14.19.46; desD (gene name). Cat No: EXWM-1011. | |
| sn-1 oleoyl-lipid 12-desaturase | The enzyme, characterized from cyanobacteria, introduces a cis double bond at carbon 12 of oleoyl groups (18:1) attached to the sn-1 position of glycerolipids. The enzyme is a methyl-end desaturase, introducing the new double bond between a pre-existing double bond and the methyl-end of the fatty acid. It is nonspecific with respect to the polar head group of the glycerolipid. Group: Enzymes. Synonyms: desA (gene name). Enzyme Commission Number: EC 1.14.19.45. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1010; sn-1 oleoyl-lipid 12-desaturase; EC 1.14.19.45; desA (gene name). Cat No: EXWM-1010. | |
| sn-1 stearoyl-lipid 9-desaturase | The enzyme, characterized from cyanobacteria, introduces a cis double bond at carbon 9 of stearoyl groups (18:0) attached to the sn-1 position of glycerolipids. The enzyme is nonspecific with respect to the polar head group of the glycerolipid. Group: Enzymes. Synonyms: desC (gene name). Enzyme Commission Number: EC 1.14.19.28. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0991; sn-1 stearoyl-lipid 9-desaturase; EC 1.14.19.28; desC (gene name). Cat No: EXWM-0991. | |
| SN 2 | SN 2 is a novel and potent small molecule activator of TRPML3. Its EC50 value is 1.13 uM. It had a similar synergistic effect and reached up-to 10-fold enhancement of the combined response when compared with the individual responses. Synonyms: SN 2; SN2; SN-2; 5-mesityl-3-oxa-4-azatricyclo[5.2.1.0~2,6~]dec-4-ene. Grades: >98%. CAS No. 823218-99-1. Molecular formula: C17H21NO. Mole weight: 255.35. | |
| SN 2 | SN 2. Group: Biochemicals. Grades: Purified. CAS No. 823218-99-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SN 2 | SN 2 is a potent activator of TRPML3 ion channel with an EC 50 of 1.8 μM [1]. SN 2 also acts as a potent inhibitor of Dengue virus 2 (DENV2) and Zika virus (ZIKV) [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 823218-99-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-16696. | |
| S(+)-N-(2-(2-Thienyl)ethyl)-2-chlorophenyl Glycine Methyl Ester Hydrochloride | S(+)-N-(2-(2-Thienyl)ethyl)-2-chlorophenyl Glycine Methyl Ester Hydrochloride is an impurity from Clopidogrel (C587250) which acts as an anti-platelet agent. Group: Biochemicals. Alternative Names: (α S) -2-Chloro-α - [ [2- (2-thienyl) ethyl] amino] benzeneacetic Acid Methyl Ester Hydrochloride; (S) -2-chloro-α - [ [2- (2-thienyl) ethyl] amino] benzeneacetic Acid Methyl Ester Hydrochloride; (α S) -2-Chloro-α - [ [2- (2-thienyl) ethyl] amino] benzeneacetic Acid Methyl Ester Hydrochloride; (+)-(S)-Methyl α-[[2-(2-Thienyl)ethyl]amino]-α-(2-chlorophenyl)acetate Hydrochloride; (S)-(+)-Methyl α-[[2-(Thien-2-yl)ethyl]amino]-α-(2-chlorophenyl)acetate Hydrochloride. Grades: Highly Purified. CAS No. 141109-19-5. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| SN-23862 | SN-23862 is a bioreductive agent with potential anticancer activity. SN-23862 is analogue of CB-1954, a dinitrobenzamide aziridine with nitrogen mustard. SN-23862 is also a prodrug that is activated by enzymatic nitroreduction in tumor. Synonyms: SN23862; SN 23862; 5-(N,N-Bis(2-chloroethyl)amino)-2,4-dinitrobenzamide. CAS No. 142439-61-0. Molecular formula: C11H12Cl2N4O5. Mole weight: 351.14. | |
| SN-28049 | SN-28049SN is a DNA intercalating drug that binds selectively to GC-rich DNA and shows curative activity against the Colon 38 adenocarcinoma in mice. SN 28049 has a complex action that may involve poisoning of topo IIalpha, suppression of topo I and inhibition of gene transcription from promoters with SP-1 sites. These actions may contribute to the promising experimental solid tumour anticancer activity of SN 28049. Synonyms: SN28049; SN 28049; N-(2-(dimethylamino)ethyl)-2,6-dimethyl-1-oxo-1,2-dihydrobenzo[b][1,6]naphthyridine-4-carboxamide. CAS No. 492472-30-7. Molecular formula: C19H22N4O2. Mole weight: 338.41. | |
| sn-2 acyl-lipid ω-3 desaturase (ferredoxin) | This plastidial enzyme desaturates 16:2 fatty acids attached to the sn-2 position of glycerolipids to 16:3 fatty acids, and converts18:2 to 18:3 in both the sn-1 and sn-2 positions. It acts on all 16:2- or 18:2-containing chloroplast membrane lipids, including phosphatidylglycerol, monogalactosyldiacylglycerol, digalactosyldiaclyglycerol, and sulfoquinovosyldiacylglycerol. The enzyme introduces a cis double bond at a location 3 carbons away from the methyl end of the fatty acid. The distance from the carboxylic acid end of the molecule does not affect the location of the new double bond. cf. EC 1.14.19.25, acyl-lipid ω-3 desaturase (cytochrome b5) and EC 1.14.19.36, sn-1 acyl-lipid ω-3 desaturase (ferredoxin). Group: Enzymes. Synonyms: FAD7; FAD8. Enzyme Commission Number: EC 1.14.19.35. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0999; sn-2 acyl-lipid ω-3 desaturase (ferredoxin); EC 1.14.19.35; FAD7; FAD8. Cat No: EXWM-0999. | |
| sn-2 palmitoyl-lipid 9-desaturase | The enzyme, characterized from the cyanobacterium Nostoc sp. 36, introduces a cis double bond at carbon 9 of palmitoyl groups (16:0) attached to the sn-2 position of glycerolipids. Group: Enzymes. Synonyms: DesC2. Enzyme Commission Number: EC 1.14.19.27. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0990; sn-2 palmitoyl-lipid 9-desaturase; EC 1.14.19.27; DesC2. Cat No: EXWM-0990. | |
| SN 38 | SN 38. Group: Biochemicals. Grades: Purified. CAS No. 86639-52-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SN-38 | SN-38 is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 inhibits DNA and RNA synthesis with IC 50 s of 0.077 and 1.3 μM, respectively. SN-38 is a payload of sacituzumab govitecan (HY -132254) [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: 7-Ethyl-10-hydroxycamptothecin. CAS No. 86639-52-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-13704. | |
| SN-38. (7-Ethyl-10-hydroxycamptothecin) | A metabolite of Irinotecan, a DNA topoisomerase inhibitor. Group: Biochemicals. Alternative Names: 7-Ethyl-10-hydroxycamptothecin. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| SN-38 Carboxylate Disodium Salt. | The active metabolite of. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| SN-38 glucuronide | SN-38 glucuronide is an inactive metabolite of the anticancer active molecule Irinotecan (HY-16562) and has toxic effects on the gastrointestinal tract. Irinotecan is a topoisomerase I inhibitor which can be used for researching colon and rectal cancer [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SN-38G. CAS No. 121080-63-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-126373. | |
| SN-38 Glucuronide | A metabolite of Irinotecan. Synonyms: 7-Ethyl-10-hydroxy-camptothecin-10-O-b-Dglucuronide; (4S)-4,11-Diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl b-D-glucopyranosiduronic acid. Grades: > 95%. CAS No. 121080-63-5. Molecular formula: C28H28N2O11. Mole weight: 568.53. | |
| SN-38 tri-O-acetyl-b-D-glucuronic acid methyl ester | SN-38 tri-O-acetyl-b-D-glucuronic acid methyl ester: A potent prodrug used in the field of biomedicine for targeted chemotherapy. This compound is derived from irinotecan and is transformed into SN-38, an active metabolite, within the body. Synonyms: (S)-4,11-Diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl b-D-glucopyranosiduronic acid methyl ester 2,3,4-triacetate. CAS No. 121098-77-9. Molecular formula: C35H36N2O14. Mole weight: 708.67. | |
| S-[N- (3-Phenylpropyl) (thiocarbamoyl)]-L-cysteine | Induction of Glutath. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 200mg. US Biological Life Sciences. | Worldwide |
| SN40 | SN40 is a potent amino acid transport (AAT) inhibitor with K i s of 7.29 μM, 2.42 μM, 2.94 μM, 5.55 μM, 24.43 μM and 5.55 μM for rat ASCT2, human ASCT2, EAAT1, EAAT2, EAAC1 and EAAT5, respectively. SN40 can be used for researching anticancer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2768663-14-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-146241. | |
| SN40 hydrochloride | SN40 hydrochloride is a potent amino acid transport (AAT) inhibitor with K i s of 7.29 μM, 2.42 μM, 2.94 μM, 5.55 μM, 24.43 μM and 5.55 μM for rat ASCT2, human ASCT2, EAAT1, EAAT2, EAAC1 and EAAT5, respectively. SN40 hydrochloride can be used for researching anticancer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2768663-15-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-146241B. | |
| SN50 | SN50, a cell-permeable peptide inhibitor of NF-Κb, prevents tissue destruction (epithelial defects/ulceration) in a mouse cornea after a central alkali burn. Synonyms: Nuclear Factor NF-KB Inhibitor SN50; NFkappaB Inhibitor. Grades: ≥97% by HPLC. CAS No. 213546-53-3. Molecular formula: C129H230N36O29S. Mole weight: 2781.5. | |
| SN 6 | SN 6. Group: Biochemicals. Alternative Names: 2-[[4-[ (4-Nitrophenyl) methoxy]phenyl]methyl]-4-thiazolidinecarboxylic Acid Ethyl Ester. Grades: Highly Purified. CAS No. 415697-08-4. Pack Sizes: 10mg. Molecular Formula: C20H22N2O5S, Molecular Weight: 402.46. US Biological Life Sciences. | Worldwide |
| SN-6 | SN-6 is a selective Na+/Ca2+-exchange (NCX) inhibitor that displays some selectivity for NCX1 (IC50 = 2.9, 16 and 8.6 μM for inhibition of intracellular Na+-dependent 45Ca2+ uptake by cells expressing NCX1, NCX2 and NCX3, respectively). SN-6 shows some affinity for mACh receptors (IC50 = 18 μM) but minimal activity against NCKX2 and various receptors and ion channels (IC50 > 30 μM). SN-6 exhibits anti-ischemic activity. Synonyms: SN-6; SN 6; SN6; 2-[[4-[(4-Nitrophenyl)methoxy]phenyl]methyl]-4-thiazolidinecarboxylic acid ethyl ester. Grades: ≥99% by HPLC. CAS No. 415697-08-4. Molecular formula: C20H22N2O5S. Mole weight: 402.16. | |
| SN-6 | SN-6. Group: Biochemicals. Grades: Purified. CAS No. 415697-08-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SN-706 | SN-706 is an anthracycline antibiotic produced by Actinomadura reseoviolacea var miuraensis. It is active against gram-positive and gram-negative bacteria, as well as inhibits KB and HeLa cells with IC50 of 0.54 ng/mL. Synonyms: Antibiotic SN 706; SN 706. CAS No. 114511-93-2. Molecular formula: C36H45NO14. Mole weight: 715.7. | |
| SNA-4606-1 | SNA-4606-1 is an elaiophylin antibiotic isolated from Streptomyces sp. SNA-4606. It acts as a testosterone 5 alpha-reductase inhibitor with IC50 of 6.6 μmol/L. Molecular formula: C52H84O18. Mole weight: 997.2. | |
| SNA-4606-2 | SNA-4606-2 is an elaiophylin antibiotic isolated from Streptomyces sp. SNA-4606. It acts as a testosterone 5 alpha-reductase inhibitor with IC50 of 8.7 μmol/L. Molecular formula: C53H86O18. Mole weight: 1011.24. | |
| SNA-4606-3 | SNA-4606-3 is an elaiophylin antibiotic isolated from Streptomyces sp. SNA-4606. It acts as a testosterone 5 alpha-reductase inhibitor. Molecular formula: C55H90O17. Mole weight: 1023.3. | |
| SNA-60-367 | SNA-60-367 are a group of aromatase inhibitors produced by soil bacterium, Bacillus sp. SNA-60-367. These inhibitors are a family of acylated decapeptides that differ from each other in terms of amino acid composition and the nature of the fatty acid side chain. | |
| SNA-8073B | SNA-8073A is an isotetracenone antibiotic isolated from the broth filtrate of Streptomyces sp. SNA-8073. It inhibited prolyl endopeptidase of Flavobacterium non-competitively with IC50 of 8.9 μmol/L. Synonyms: SNA-8073-B. Molecular formula: C20H16O5. Mole weight: 336.3. | |
| snake venom factor V activator | Known from venom of Vipera russelli. Inhibited by di-isopropyl fluorophosphate, unlike the metallopeptidase russellysin (EC 3.4.24.58) that is specific for factor X. In peptidase family S1 (trypsin family). Group: Enzymes. Enzyme Commission Number: EC 3.4.21.95. CAS No. 471269-12-2, 123757-15-3, 123757-16-4, 123757-17-5, 123757-18-6. Factor V activator. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4187; snake venom factor V activator; EC 3.4.21.95; 471269-12-2, 123757-15-3, 123757-16-4, 123757-17-5, 123757-18-6. Cat No: EXWM-4187. | |
| Snakin-2 | Snakin-2 is an antibacterial peptide isolated from Solanum tuberosum. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Ser-Tyr-Lys-Lys-Ile-Asp-Cys-Gly-Gly-Ala-Cys-Ala-Ala-Arg-Cys. | |
| Snakin-Z | Snakin-Z is an antimicrobial peptide (AMP) isolated from jujube fruit. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Cys-Ala-Arg-Leu-Asn-Cys-Val-Pro-Lys-Gly-Thr-Ser-Gly-Asn-Thr-Glu-Thr-Cys-Pro-Cys-Tyr-Ala-Ser-Leu-His-Ser-Cys-Arg-Lys-Tyr-Gly. | |
| SnAP 2,3-Bicyclo-(3,4-Pyr) M Reagent | SnAP 2,3-Bicyclo-(3,4-Pyr) M Reagent. Group: Salt. Product ID: tert-butyl (3S,4S)-3-amino-4-(tributylstannylmethoxy)pyrrolidine-1-carboxylate. Molecular formula: 505.3g/mol. Mole weight: C22H46N2O3Sn. CCCC[Sn] (CCCC) (CCCC)COC1CN (CC1N)C (=O)OC (C) (C)C. InChI=1S/C10H19N2O3. 3C4H9. Sn/c1-10(2, 3)15-9(13)12-5-7(11)8(6-12)14-4; 3*1-3-4-2; /h7-8H, 4-6, 11H2, 1-3H3; 3*1, 3-4H2, 2H3; /t7-, 8-; ; ; ; /m0. /s1. URTKNAYUDTUPJM-CFACWHMASA-N. |  |
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