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| Product | Description | |
|---|---|---|
| (S)-(-)-Thalidomide | (S)-(-)-Thalidomide. Group: Biochemicals. Alternative Names: (S)-(-)-2-(2,6-Dioxo-3-piperidinyl)-1H-iso-indole-1,3(2H)-dione; (S)-Thalidomide; NSC 91730. Grades: Highly Purified. CAS No. 841-67-8. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C13H10N2O4. US Biological Life Sciences. |  Worldwide |
| (S)-(-)-Thalidomide ((S)-(-)-2-(2,6-Dioxo-3-piperidinyl)-1H-iso-indole-1,3(2H)-dione) | Optically active isomer of Thalidomide, which inhibits FGF-induced angiogenesis. Inhibits replication of human immunodeficiency virus type 1. Teratogenic sedative. Group: Biochemicals. Alternative Names: (S)-(-)-2-(2,6-Dioxo-3-piperidinyl)-1H-iso-indole-1,3(2H)-dione. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| (R)-(+)-Thalidomide ((R)-(+)-2-(2,6-Dioxo-3-piperidinyl)-1H-iso-indole-1,3(2H)-dione) | Optically active isomer of Thalidomide, which inhibits FGF-induced angiogenesis. Inhibits replication of human immunodeficiency virus type 1. Teratogenic sedative. Group: Biochemicals. Alternative Names: (R)-(+)-2-(2,6-Dioxo-3-piperidinyl)-1H-iso-indole-1,3(2H)-dione. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| (S)-Thalidomide | (S)-Thalidomide ((S)-(-)-Thalidomide) is the S-enantiomer of Thalidomide. (S)-Thalidomide has immunomodulatory, anti-inflammatory, antiangiogenic and pro-apoptotic effects [1] [2] [3]. (S)-Thalidomide induces teratogenic effects by binding to cereblon (CRBN) [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (S)-(-)-Thalidomide. CAS No. 841-67-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14658A. |  |
| S-Thalidomide | The S-enantiomer of Thalidomide which is a selective inhibitor of tumor necrosis factor α (TNF-α) synthesis. Synonyms: (S)-Thalidomide; (-)-Thalidomide; 841-67-8; l-Thalidomide; S-(-)-Thalidomide. Grades: > 95%. CAS No. 841-67-8. Molecular formula: C13H10N2O4. Mole weight: 258.24. |  |
| (±)-Thalidomide ((RS)-2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione) | Cell-permeable. A teratogen and sedative-hypnotic with inherent anti-inflammatory properties. A selective inhibitor of tumor necrosis factor a (TNF-a) synthesis. Thalidomide initiates its teratogenic effects by binding to cereblon (CRBN), a thalidomide-binding protein, and inhibiting the associated ubiquitin ligase activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 50-35-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| 1-Piperazinehexanoic acid-thalidomide | 1-Piperazinehexanoic acid-thalidomide is a conjugate of E3 ligase ligand and linker that serve as a key intermediate for the synthesis of complete JMV7048 (HY-162704) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2819682-33-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-162737. | |
| 2-(2,6-Dioxo-3-piperidinyl)-4-hydroxyisoindoline-1,3-dione | Thalidomide-OH is a ligand for E3 ligase used in PROTAC technology. Synonyms: 4-Hydroxy thalidomide; E3 ligase Ligand 2; Thalidomide-4-OH; 4-Hydroxy thalidomide, (+/-)-; 3-Hydroxythalidomide; 4-Hydroxy-thalidomide; α-(3-Hydroxy-phthalimido)-glutarimid; 2-(2,6-dioxopiperidin-3-yl)-4-hydroxyisoindoline-1,3-dione; 2-(2,6-dioxo-3-piperidinyl)-4-hydroxy-1H-isoindole-1,3(2H)-dione. Grades: > 95 %. CAS No. 5054-59-1. Molecular formula: C13H10N2O5. Mole weight: 274.23. | |
| 4-Hydroxy Thalidomide | A metabolite of Thalidomide which was prescribed as an anti-nausea agent to help pregnant women with morning sickness but withdrawn from the market when it was discovered to cause birth defects. Synonyms: 4-Hydroxy thalidomide; E3 ligase Ligand 2; 2-(2,6-dioxopiperidin-3-yl)-4-hydroxyisoindoline-1,3-dione; 4-Hydroxythalidomide; Thalidomide-4-OH; 2-(2,6-dioxopiperidin-3-yl)-4-hydroxyisoindole-1,3-dione; 2-(2,6-Dioxo-3-piperidinyl)-4-hydroxyisoindoline-1,3-dione; 4-Hydroxy-thalidomide; 4-Hydroxy thalidomide, (+/-)-; E3 ligase Ligand 2 (Thalidomide-OH); J344NHC6VB; C13H10N2O5; MFCD03699892; Phthalimide, N-(2,6-dioxo-3-piperidyl)-3-hydroxy-; 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-hydroxy-; 2-(2,6-dioxopiperidin-3-yl)-4-hydroxy-2,3-dihydro-1H-isoindole-1,3-dione;2-(2,6-Dioxo-piperidin-3-yl)-4-hydroxy-isoindole-1,3-dione; 2-(2,6-dioxo-piperidine-3-yl)-4-hydroxy-isoindole-1,3-dione; 4-hydroxy-2-(2,6-dioxo(3-piperidyl))isoindoline-1,3-dione. Grades: > 95%. Molecular formula: C13H10N2O5. Mole weight: 274.24. | |
| Azido-Thalidomide | Azido-Thalidomide is a crosslinker-E3 ligase ligand conjugate consisting of an E3 ligase ligand thalidomide conjugated to an alkyl linker with terminal azide group. Synonyms: E3 ligase Ligand-Linker Conjugates 18; N-(4-azidobutyl)-2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyacetamide. Grades: ≥98%. CAS No. 2098488-36-7. Molecular formula: C19H20N6O6. Mole weight: 428.405. | |
| FHD-609 | FHD-609 is a PROTAC degrader and inhibitor of BRD9 ( Bromodomain-containing protein 9 ). FHD-609 targets to ncBAF , can be used for research of wide range of cancers that contain a mutation in a BAF complex subunit. FHD-609 in combination with Telomelysin or INO5401, may play a role in adrenocortical carcinoma (ACC) treatment. (Blue: BRD9 ligand-6 (HY-49393), Black: linker (HY-168309); Pink: (S)-Deoxy-thalidomide-Br (HY-168308) ) [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2676211-64-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153367. | |
| (R)-Thalidomide | (R)-Thalidomide ((R)-(+)-Thalidomide) is the R-enantiomer of Thalidomide. (R)-Thalidomide has psychomotor stabilizing properties [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (R)-(+)-Thalidomide. CAS No. 2614-6-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-14658B. | |
| (R)-(+)-Thalidomide | (R)-(+)-Thalidomide. Group: Biochemicals. Alternative Names: (R)-(+)-2-(2,6-Dioxo-3-piperidinyl)-1H-iso-indole-1,3(2H)-dione; (R)-Thalidomide; NSC 91729. Grades: Highly Purified. CAS No. 2614-6-4. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C13H10N2O4. US Biological Life Sciences. | Worldwide |
| R-Thalidomide | The R-enantiomer of Thalidomide which interacts directly with the protein cereblon (CRBN; IC50=8.5 nM), a ubiquitously-expressed E3 ligase. Synonyms: (R)-Thalidomide; (+)-Thalidomide; (R)-(+)-thalidomide; D-Thalidomide; 2614-06-4; R-(+)-Thalidomide; Thalidomide, (R)-; QN61H68KLK; 2-[(3R)-2,6-dioxopiperidin-3-yl]isoindole-1,3-dione; CHEBI:61917; Phthalimide, N-(2,6-dioxo-3-piperidyl)-, D-(+)-; (R)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione; 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-, (R)-; 2-[(3R)-2,6-dioxopiperidin-3-yl]-2,3-dihydro-1H-isoindole-1,3-dione; 2-[(3R)-2,6-dioxopiperidin-3-yl]-1H-isoindole-1,3(2H)-dione; 2-[(3~{R})-2,6-bis(oxidanylidene)piperidin-3-yl]isoindole-1,3-dione; NSC 91729; NSC-91729; (R)-(D)-Thalidomide. Grades: > 95%. CAS No. 2614-6-4. Molecular formula: C13H10N2O4. Mole weight: 258.24. | |
| TC-E3 5032 | TC-E3 5032 is a linker used in PROTAC technology that can be used in the synthesis of HDAC6 and anaplastic lymphoma kinase (ALK) degraders. Synonyms: E3 ligase Ligand 4; 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-fluoro-; Thalidomide 4-fluoride; Thalidomide fluoride; 4-Fluoro-thalidomide; Cereblon ligand 4;E3 ligase Ligand 4; 2-(2,6-Dioxo-3-piperidinyl)-4-fluoro-1H-isoindole-1,3(2H)-dione. Grades: ≥ 98%. CAS No. 835616-60-9. Molecular formula: C13H9FN2O4. Mole weight: 276.22. | |
| (+/-)-Thalidomide | (+/-)-Thalidomide. Group: Biochemicals. Grades: Highly Purified. CAS No. 50-35-1. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C13H10N2O4. US Biological Life Sciences. | Worldwide |
| 1,2-Dibromo-4,5-dimethylbenzene | 1,2-Dibromo-4,5-dimethylbenzene is used as a reagent in the synthesis of Thalidomide (T338850); an inhibitor of FGF-induced angiogenesis and replication of human immunodeficiency virus type 1. Also a teratogenic sedative and immunomodulatory agent used primarily in combination with dexamethasone to treat multiple myeloma. Group: Biochemicals. Grades: Highly Purified. CAS No. 24932-48-7. Pack Sizes: 1g, 5g. Molecular Formula: C8H8Br2, Molecular Weight: 263.959999999999. US Biological Life Sciences. | Worldwide |
| 1-Indanone | 1-Indanone is an oxidation product of Indan, a component of fuels, solvents, and varnishes. 1-Indanone is also a metabolite of Thalidomide that has been shown to inhibit the attachment of tumor cells to concanavalin A coated plastic surfaces. Group: Biochemicals. Alternative Names: Indanone; 1-Indone; 1H-Indan-1-one; 2,3-Dihydro-1-indenone; 2,3-Dihydro-1H-inden-1-one; 3-Dihydro-1H-inden-1-one; NSC 2581; α-Hydrindone; α-Indanone. Grades: Highly Purified. CAS No. 83-33-0. Pack Sizes: 25g. US Biological Life Sciences. | Worldwide |
| 1-Methylindan | 1-Methylindan is a component of fuels that is synthesized from 1-indanone (I499900). 1-Indanone is an oxidation product of Indan, a component of fuels, solvents, and varnishes. 1-Indanone is also a metabolite of Thalidomide that has been shown to inhibit the attachment of tumor cells to concanavalin A coated plastic surfaces. Group: Biochemicals. Grades: Highly Purified. CAS No. 767-58-8. Pack Sizes: 100mg, 1g. Molecular Formula: C10H12. US Biological Life Sciences. | Worldwide |
| 2-(2-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)ethoxy)ethoxy)acetaldehyde | 2-(2-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)ethoxy)ethoxy)acetaldehyde. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Thalidomide-O-PEG2-CH2-Ald. Product Category: E3 Ligase Ligand. CAS No. 2286368-58-7. Molecular formula: C19H20N2O8. Mole weight: 404.3707. IUPACName: 2-[2-[2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyethoxy]ethoxy]acetaldehyde. Product ID: PR2286368587. Alfa Chemistry ISO 9001:2015 Certified. |  |
| 2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetic acid | 2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetic acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Thalidomide-O-COOH; E3 ligase Ligand 3; Thalidomide-Acid. Product Category: PROTAC Library. CAS No. 1061605-21-7. Molecular formula: C15H12N2O7. Mole weight: 332.265. IUPACName: 2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyacetic acid. Product ID: PR1061605217. Alfa Chemistry ISO 9001:2015 Certified. | |
| 2-(2-(2-aminoethoxy)ethoxy)-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl)acetamide | 2-(2-(2-aminoethoxy)ethoxy)-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl)acetamide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Thalidomide-amido-PEG2-NH2. Product Category: PROTAC Library. CAS No. 2380273-72-1. Molecular formula: C19H22N4O7. Mole weight: 418.4006. IUPACName: 2-[2-(2-aminoethoxy)ethoxy]-N-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]acetamide. Product ID: PR2380273721. Alfa Chemistry ISO 9001:2015 Certified. | |
| 2-(2,6-Dioxo-3-piperidinyl)-4-fluoro-1H-isoindole-1,3(2H)-dione | 2-(2,6-Dioxo-3-piperidinyl)-4-fluoro-1H-isoindole-1,3(2H)-dione is an intermediate in the synthesis of N-[2-Aminoethyl] Pomalidomide TFA Salt (A6095150. N-[2-Aminoethyl] Pomalidomide TFA is a thalidomide derivative, a potent inhibitor of TNF-α production. It is an anti-inflammatory and anti-tumor agent used in the treatment of multiple myeloma. Group: Biochemicals. Grades: Highly Purified. CAS No. 835616-60-9. Pack Sizes: 500mg, 1g. Molecular Formula: C13H9FN2O4. US Biological Life Sciences. | Worldwide |
| 2-(2,6-dioxopiperidin-3-yl)-4-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)isoindoline-1,3-dione | 2-(2,6-dioxopiperidin-3-yl)-4-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)isoindoline-1,3-dione. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Thalidomide-O-PEG3-alcohol. Product Category: E3 Ligase Ligand. CAS No. 2286368-57-6. Molecular formula: C19H22N2O8. Mole weight: 406.3866. IUPACName: 2-(2,6-dioxopiperidin-3-yl)-4-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]isoindole-1,3-dione. Product ID: PR2286368576. Alfa Chemistry ISO 9001:2015 Certified. | |
| 2-(2,6-dioxopiperidin-3-yl)-4-fluoro-2,3-dihydro-1H-isoindole-1,3-dione | 2-(2,6-dioxopiperidin-3-yl)-4-fluoro-2,3-dihydro-1H-isoindole-1,3-dione. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Thalidomide 4-fluoride. Product Category: PROTAC Library. CAS No. 835616-60-9. Molecular formula: C13H9FN2O4. Mole weight: 276.22. IUPACName: 2-(2,6-dioxopiperidin-3-yl)-4-fluoroisoindole-1,3-dione. Product ID: PR835616609. Alfa Chemistry ISO 9001:2015 Certified. | |
| 2-(2,6-dioxopiperidin-3-yl)-5-fluoro-2,3-dihydro-1H-isoindole-1,3-dione | 2-(2,6-dioxopiperidin-3-yl)-5-fluoro-2,3-dihydro-1H-isoindole-1,3-dione. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Thalidomide 5-fluoride. Product Category: PROTAC Library. CAS No. 835616-61-0. Molecular formula: C13H9FN2O4. Mole weight: 276.22. IUPACName: 2-(2,6-dioxopiperidin-3-yl)-5-fluoroisoindole-1,3-dione. Product ID: PR835616610. Alfa Chemistry ISO 9001:2015 Certified. | |
| 2-(2,6-dioxopiperidin-3-yl)-5-fluoro-6-(piperazin-1-yl)-2,3-dihydro-1H-isoindole-1,3-dione | 2-(2,6-dioxopiperidin-3-yl)-5-fluoro-6-(piperazin-1-yl)-2,3-dihydro-1H-isoindole-1,3-dione. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Thalidomide-Piperazine 5-fluoride. Product Category: PROTAC Library. CAS No. 2222114-22-7. Molecular formula: C17H17FN4O4. Mole weight: 360.3397. Purity: 0.99. IUPACName: 2-(2,6-dioxopiperidin-3-yl)-5-fluoro-6-piperazin-1-ylisoindole-1,3-dione. Product ID: PR2222114227. Alfa Chemistry ISO 9001:2015 Certified. | |
| 2-(2,6-dioxopiperidin-3-yl)-5-methylisoindoline-1,3-dione | 2-(2,6-dioxopiperidin-3-yl)-5-methylisoindoline-1,3-dione. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Thalidomide-5-methyl. Product Category: PROTAC Library. CAS No. 40313-92-6. Molecular formula: C14H12N2O4. Mole weight: 272.2561. IUPACName: 2-(2,6-dioxopiperidin-3-yl)-5-methylisoindole-1,3-dione. Product ID: PR40313926. Alfa Chemistry ISO 9001:2015 Certified. | |
| 2,3-Naphthalic Anhydride | 2,3-Naphthalic anhydride is used as a reagent to synthesize analogues of Thalidomide (T338850), an inhibitor of tumor necrosis factor that was once abandoned because it caused birth defects, but is currently used as an inhibitor of angiogenesis in patients with multiple myeloma. Group: Biochemicals. Grades: Highly Purified. CAS No. 716-39-2. Pack Sizes: 100mg, 1g. Molecular Formula: C12H6O3. US Biological Life Sciences. | Worldwide |
| 2-(4-Amino-1-oxoisoindolin-2-yl)pentanediamide | 2-(4-Amino-1-oxoisoindolin-2-yl)pentanediamide is an impurity of Lenalidomide (L328000), an immunomodulatory drug; analog of Thalidomide. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 50mg. Molecular Formula: C13H16N4O3, Molecular Weight: 276.29. US Biological Life Sciences. | Worldwide |
| 2-(4-Nitro-1-oxoisoindolin-2-yl)pentanedioic Acid | 2-(4-Nitro-1-oxoisoindolin-2-yl)pentanedioic Acid is an impurity of Lenalidomide (L328000), an immunomodulatory drug; analog of Thalidomide. Group: Biochemicals. Grades: Highly Purified. CAS No. 295357-72-1. Pack Sizes: 10mg, 50mg. Molecular Formula: C13H12N2O7, Molecular Weight: 308.24. US Biological Life Sciences. | Worldwide |
| 2-Bromomethyl-6-nitrobenzoic Acid Methyl Ester | 2-Bromomethyl-6-nitrobenzoic Acid Methyl Ester is a potential cyclooxygenase inhibitor derived from thalidomide (T338850), an immunomodulatory agent used primarily in combination with dexamethasone to treat multiple myeloma. Group: Biochemicals. Alternative Names: Methyl 2-(2-Bromomethyl)-6-nitrobenzoate; Methyl 2-(Bromomethyl)-6-nitrobenzoate. Grades: Highly Purified. CAS No. 61940-21-4. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| 2-Phthalimidino-glutaric Acid | 2-Phthalimidino-glutaric acid is a stable analog of thalidomide. Group: Biochemicals. Grades: Highly Purified. CAS No. 26577-32-2. Pack Sizes: 5mg, 10mg. Molecular Formula: C13H13NO5, Molecular Weight: 263.25. US Biological Life Sciences. | Worldwide |
| 3-(2-(2-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)ethoxy)ethoxy)propanoic acid | 3-(2-(2-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)ethoxy)ethoxy)propanoic acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Pomalidomide-PEG3-CO2H; Thalidomide-NH-PEG3-propionic acid. Product Category: PROTAC Library. CAS No. 2138440-82-9. Molecular formula: C22H27N3O9. Mole weight: 477.4645. IUPACName: 3-[2-[2-[2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]ethoxy]ethoxy]ethoxy]propanoic acid. Product ID: PR2138440829. Alfa Chemistry ISO 9001:2015 Certified. | |
| 3-(2-Aminoethoxy) Thalidomide | 3-(2-Aminoethoxy) Thalidomide is a derivative of Thalidomide (T338850), Inhibits FGF-induced angiogenesis. Inhibits replication of human immunodeficiency virus type 1. Teratogenic sedative. There is now a growing clinical interest in Thalidomide, and it is introduced as an immunomodulatory agent used primarily in combination with dexamethasone to treat multiple myeloma. Group: Biochemicals. Grades: Highly Purified. CAS No. 390367-50-7. Pack Sizes: 5mg, 10mg. Molecular Formula: C15H15N3O5, Molecular Weight: 317.3. US Biological Life Sciences. | Worldwide |
| 3-[2-Aminoethoxy) Thalidomide BP-1-108 Amide | 3-[2-Aminoethoxy) Thalidomide BP-1-108 Amide is a potential small molecule inhibitor of Stat3 and Stat5-SH2 domain. Useful in the treatment of human cancers. Antileukemia agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2mg. Molecular Formula: C47H51N5O10S, Molecular Weight: 878. US Biological Life Sciences. | Worldwide |
| 3-(2-Aminoethoxy) Thalidomide SF-1-088 Amide | 3-(2-Aminoethoxy) Thalidomide SF-1-088 Amide is a derivative of Pomalidomide, which is an immunomodulatory antineoplastic agent for the treatment of multiple myeloma. Synonyms: 2-Methyl-2-propanyl {2-[(4-cyclohexylbenzyl){4-[(2-{[2-(2,6-dioxo-3-piperidinyl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]oxy}ethyl)carbamoyl]-3-hydroxyphenyl}amino]-2-oxoethyl}[(4-methylphenyl)sulfonyl]carbamate; Carbamic acid, N-[2-[[(4-cyclohexylphenyl)methyl][4-[[[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]ethyl]amino]carbonyl]-3-hydroxyphenyl]amino]-2-oxoethyl]-N-[(4-methylphenyl)sulfonyl]-, 1,1-dimethylethyl ester. Molecular formula: C49H53N5O12S. Mole weight: 936.03. | |
| 3-(2-Aminoethoxy) Thalidomide SF-1-088 Amide | 3-(2-Aminoethoxy) Thalidomide SF-1-088 Amide is a potential small molecule inhibitor of Stat3 and Stat5-SH2 domain. Useful in the treatment of human cancers. Antileukemia agent. Derivative of Thalidomide (T338850), Inhibits FGF-induced angiogenesis. Inhibits replication of human immunodeficiency virus type 1. Teratogenic sedative. There is now a growing clinical interest in Thalidomide, and it is introduced as an immunomodulatory agent used primarily in combination with dexamethasone to treat multiple myeloma. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2mg. Molecular Formula: C49H53N5O12S, Molecular Weight: 936.04. US Biological Life Sciences. | Worldwide |
| 3-(4-Amino-1,3-dihydro-5-hydroxy-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione | 3-(4-Amino-1,3-dihydro-5-hydroxy-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione is a related compound of Lenalidomide (L328000), an immunomodulatory drug and an analog of Thalidomide. Group: Biochemicals. Grades: Highly Purified. CAS No. 1421593-78-3. Pack Sizes: 5mg, 10mg. Molecular Formula: C13H13N3O4, Molecular Weight: 275.26. US Biological Life Sciences. | Worldwide |
| 3-[4- (Aminomethyl) benzyloxy] Thalidomide | 3-[4- (Aminomethyl) benzyloxy] Thalidomide is a derivative of Thalidomide (T338850), Inhibits FGF-induced angiogenesis. Inhibits replication of human immunodeficiency virus type 1. Teratogenic sedative. There is now a growing clinical interest in Thalidomide, and it is introduced as an immunomodulatory agent used primarily in combination with dexamethasone to treat multiple myeloma. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C21H19N3O5, Molecular Weight: 393.39. US Biological Life Sciences. | Worldwide |
| 3-[4-(Aminomethyl)benzyloxy] Thalidomide | 3-[4-(Aminomethyl)benzyloxy] Thalidomide is a derivative of Pomalidomide, which is an immunomodulatory antineoplastic agent for the treatment of multiple myeloma. Synonyms: 4-[[4-(aminomethyl)phenyl]methoxy]-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione; 4-{[4-(Aminomethyl)benzyl]oxy}-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione; 1H-Isoindole-1,3(2H)-dione, 4-[[4-(aminomethyl)phenyl]methoxy]-2-(2,6-dioxo-3-piperidinyl)-. Molecular formula: C21H19N3O5. Mole weight: 393.39. | |
| 3-[4-Aminomethyl) benzyloxy]thalidomide BP-1-108 Amide | 3-[4-Aminomethyl) benzyloxy]thalidomide BP-1-108 Amide is a potential small molecule inhibitor of Stat3 and Stat5-SH2 domain. Useful in the treatment of human cancers. Antileukemia agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2mg. Molecular Formula: C53H55N5O10S, Molecular Weight: 954.1. US Biological Life Sciences. | Worldwide |
| 3-[4- (Aminomethyl) benzyloxy] Thalidomide SF-1-088 | 3-[4- (Aminomethyl) benzyloxy] Thalidomide SF-1-088 is a potential small molecule inhibitor of Stat3 and Stat5-SH2 domain. Useful in the treatment of human cancers. Antileukemia agent. Derivative of Thalidomide (T338850), Inhibits FGF-induced angiogenesis. Inhibits replication of human immunodeficiency virus type 1. Teratogenic sedative. There is now a growing clinical interest in Thalidomide, and it is introduced as an immunomodulatory agent used primarily in combination with dexamethasone to treat multiple myeloma. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2mg. Molecular Formula: C53H55N5O10S, Molecular Weight: 954.1. US Biological Life Sciences. | Worldwide |
| 3-Amino-2,6-piperidinedione 2,2,2-Trifluoroacetate | 3-Amino-2,6-piperidinedione 2,2,2-Trifluoroacetate is an intermediate in the synthesis of Thalidomide-d4 (T338852), a labelled Thalidomide, which inhibits FGF-induced angiogenesis. Inhibits replication of human immunodeficiency virus type 1. Teratogenic sedative. Group: Biochemicals. Grades: Highly Purified. CAS No. 590365-46-1. Pack Sizes: 1g, 10g. Molecular Formula: C7H9F3N2O4, Molecular Weight: 242.15. US Biological Life Sciences. | Worldwide |
| 3-Amino-piperidine-2,6-dione | 3-Amino-piperidine-2,6-dione is used for studies on the hydrolytic degradation and primary metabolic pathway of thalidomide in animals and human liver microsomes. Thalidomide is a sedative drug used to treat morning sickness. Group: Biochemicals. Grades: Highly Purified. CAS No. 2353-44-8. Pack Sizes: 250mg, 500mg. Molecular Formula: C5H8N2O2, Molecular Weight: 128.13. US Biological Life Sciences. | Worldwide |
| 3-Hydroxy Thalidomide | A metabolite of Thalidomide which was prescribed as an anti-nausea agent to help pregnant women with morning sickness but withdrawn from the market when it was discovered to cause birth defects. Grades: > 95%. Molecular formula: C13H10N2O5. Mole weight: 274.24. | |
| 3-Nitrophthalic acid | An impurity of Pomalidomide which is a derivative of thalidomide with antineoplastic effect. Synonyms: 3-nitrophthalic acid. Grades: 99 %. CAS No. 603-11-2. Molecular formula: C8H5NO6. Mole weight: 211.13. | |
| 4-[(2-(2-aminoethoxy)ethyl)amino]-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione | 4-[(2-(2-aminoethoxy)ethyl)amino]-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Thalidomide-NH-PEG1-NH2. Product Category: PROTAC Library. CAS No. 2138439-12-8. Molecular formula: C17H20N4O5. Mole weight: 360.3645. Purity: >98%. IUPACName: 4-[2-(2-aminoethoxy)ethylamino]-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione. Product ID: PR2138439128. Alfa Chemistry ISO 9001:2015 Certified. | |
| 4-[(5-aminopentyl)amino]-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione | 4-[(5-aminopentyl)amino]-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Thalidomide-NH-C5-NH2 (hydrochloride). Product Category: PROTAC Library. CAS No. 2093386-39-9. Molecular formula: C18H22N4O4. Mole weight: 358.3917. IUPACName: 4-(5-aminopentylamino)-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione;hydrochloride. Product ID: PR2093386399. Alfa Chemistry ISO 9001:2015 Certified. | |
| 4-[(6-aminohexyl)amino]-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione | 4-[(6-aminohexyl)amino]-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione. Uses: Designed for use in research and industrial production. Product Category: PROTAC Library. CAS No. 2093386-50-4. Molecular formula: C19H24N4O4. Mole weight: 372.4183. Purity: >95%. IUPACName: 4-(6-aminohexylamino)-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione;hydrochloride. Product ID: PR2093386504. Alfa Chemistry ISO 9001:2015 Certified. Categories: Thalidomide-NH-C6-NH2. | |
| 4-[(8-aminooctyl)amino]-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione | 4-[(8-aminooctyl)amino]-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Thalidomide-NH-C8-NH2. Product Category: PROTAC Library. CAS No. 1957236-36-0. Molecular formula: C21H28N4O4. Mole weight: 400.4714. IUPACName: 4-(8-aminooctylamino)-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione. Product ID: PR1957236360. Alfa Chemistry ISO 9001:2015 Certified. | |
| 5'-Hydroxy thalidomide | 5'-Hydroxy thalidomide. Group: Biochemicals. Alternative Names: cis-5-Hydroxy-3-phthalimidoglutarimide ; 2-(5-Hydroxy-2,6-dioxo-3-piperidinyl)-1H-Isoindole-1,3(2H)-dione. Grades: Highly Purified. CAS No. 203450-07-1. Pack Sizes: 1mg, 2mg, 5mg. Molecular Formula: C13H10N2O5. US Biological Life Sciences. | Worldwide |
| BODIPY FL Thalidomide | BODIPY FL Thalidomide. Uses: Designed for use in research and industrial production. CAS No. 2740620-18-0. Purity: 0.95. Product ID: ACM2740620180. Alfa Chemistry ISO 9001:2015 Certified. | |
| CC-1088 | CC-1088 is an analog of thalidomide with potential antineoplastic activity that belongs to the functional class of agents called selective cytokine inhibitory drugs (SelCIDs). Uses: Cytokine inhibitor. Synonyms: CC1088; CC 1088; CC-1088. 3-(1,3-dioxoisoindolin-2-yl)-3-phenylpropanamide. Grades: ≥98%. CAS No. 467421-06-3. Molecular formula: C17H14N2O3. Mole weight: 294.31. | |
| CC-3052 | CC-3052, a thalidomide analogue, reduces persistent activation of the TNF-α system in HIV without markedly impairing neutrophil viability. Synonyms: CC-3052; CC 3052; CC3052; methyl (2R)-2-(3,4-dimethoxyphenyl)-3-(3-oxo-1H-isoindol-2-yl)propanoate. Grades: >98%. CAS No. 216884-02-5. Molecular formula: C20H21NO5. Mole weight: 355.38. | |
| CPS-11 | CPS-11 (N-(Hydroxymethyl)thalidomide) a Thalidomide (HY-14658) analogue, is a potent anti-cancer agent. CPS-11 inhibits NF-κB , activates NFAT , and repress cytokine expression through elevated ROS. CPS-11 exhibits a wider activity spectrum and higher potency against MM (multiple myeloma) cell lines [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N-(Hydroxymethyl)thalidomide. CAS No. 145945-21-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-117987. | |
| Cyclopentolate Hydrochloride USP | thalidomide derivative for multiple myeloma and myelodysplastic syndromes. Grades: USP. CAS No. 5870-29-1. Product ID: 8-01776. Molecular formula: C17H25NO3 HCl. Mole weight: 327.85. Source : |  |
| D-4-Phthalimido-glutaramic Acid | Thalidomide derivative. Group: Biochemicals. Alternative Names: NSC 92155; (4R)-5-Amino-4-(1,3-dioxo-1,3-dihydro-2h-isoindol-2-yl)-5-oxopentanoic Acid. Grades: Highly Purified. CAS No. 2614-9-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Iberdomide | Iberdomide (CC-220) is an orally active and potent cereblon (CRBN) E3 ligase modulator (CELMoD) with an IC 50 of ~150?nM for cereblon-binding affinity. Iberdomide, a derivative of Thalidomide (HY-14658), has antitumor and immunostimulatory activities [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CC-220. CAS No. 1323403-33-3. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101291. | |
| Lenalidomide | Lenalidomide (CC-5013), a derivative of Thalidomide, acts as molecular glue. Lenalidomide is an orally active immunomodulator. Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN) , and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide (CC-5013) specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CC-5013. CAS No. 191732-72-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-A0003. | |
| Lenalidomide | Lenalidomide is an immunomodulatory drug; analog of Thalidomide. Group: Biochemicals. Alternative Names: 3-(4-Amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione; 1-Oxo-2-(2,6-dioxopiperidin-3-yl)-4-aminoisoindoline; CC-5013. Grades: Highly Purified. CAS No. 191732-72-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Lenalidomide hemihydrate | Lenalidomide hemihydrate (CC-5013 hemihydrate) is a derivative of Thalidomide and functions as an orally active immunomodulator. It acts through cereblon-mediated selective ubiquitination and degradation of IKZF1 and IKZF3 lymphocyte transcription factors, inhibiting the growth of mature B-cell lymphomas including multiple myeloma, and inducing interleukin-2 (IL-2) release from T cells. Synonyms: Revlimid hemihydrate; CC-5013 hemihydrate. Grades: >98%. CAS No. 847871-99-2. Molecular formula: C26H28N6O7. Mole weight: 268.27. | |
| Lenalidomide hydrochloride | Lenalidomide hydrochloride (CC-5013 hydrochloride) is a derivative of Thalidomide and functions as an orally active immunomodulator. It acts through cereblon-mediated selective ubiquitination and degradation of IKZF1 and IKZF3 lymphocyte transcription factors, inhibiting the growth of mature B-cell lymphomas including multiple myeloma, and inducing interleukin-2 (IL-2) release from T cells. Synonyms: Revlimid hydrochloride; CC-5013 hydrochloride; CC5013 hydrochloride; CC 5013 hydrochloride. Grades: >98%. CAS No. 1243329-97-6. Molecular formula: C13H14ClN3O3. Mole weight: 295.72. | |
| Lenalidomide N(imido)-Glucoside | Lenalidomide N(imido)-Glucoside is a derivative of Lenalidomide; an immunomodulatory drug and analog of Thalidomide. Synonyms: 3-(4-Amino-1-oxoisoindolin-2-yl)-1-((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)piperidine-2,6-dione. Molecular formula: C19H23N3O8. Mole weight: 421.4. | |
| Lenalidomide (Standard) | Lenalidomide (Standard) is the analytical standard of Lenalidomide. This product is intended for research and analytical applications. Lenalidomide (CC-5013), a derivative of Thalidomide, acts as molecular glue. Lenalidomide is an orally active immunomodulator. Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN) , and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide (CC-5013) specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 191732-72-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0003R. | |
| N-Hydroxy Thalidomide | A metabolite of Thalidomide which was prescribed as an anti-nausea agent to help pregnant women with morning sickness but withdrawn from the market when it was discovered to cause birth defects. Grades: > 95%. Molecular formula: C13H10N2O5. Mole weight: 274.24. | |
| NX-2127 | NX-2127 (compound 28) is an orally active PROTAC deggrader, targeting to Brutons Tyrosine Kinase (Btk). NX-2127 inhibits proliferation of BTK C481S mutant TMD8 cells, more effectively than Ibrutinib (HY-10997). NX-2127 catalyzes the degradation of Ikaros (IKZF1) and Aiolos (IKZF3) with of 25 nM and 54 nM, respectively. NX-2127 stimulates T cell activation and increases IL-2 production in primary human T Cells [1] [2]. NX-2127 is composed of PROTAC target protein ligand (red part) BTK ligand 10 (HY-168302), E3 ligase ligand (blue part) Thalidomide 5-fluoride (HY-W087383) and PROTAC Linker (black part) (S)-4-(1-(Pyrrolidin-3-ylmethyl)piperidin-4-yl)aniline (HY-168303). Among which, the conjugate of E3 ubiquitin ligase ligand + Linker compose of Thalidomide-pyrrolidine-C-piperidine-Ph-NH2 (HY-168304). Uses: Scientific research. Group: Signaling pathways. CAS No. 2416131-46-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153220. | |
| Pomalidomide | Pomalidomide is a thalidomide derivative, a potent inhibitor of TNF-α production. It is an antiinflammatory and antitumor agent used in the treatment of multiple myeloma. Group: Biochemicals. Alternative Names: 4-Amino-2-(2,6-dioxo-3-piperidinyl)isoindole-1,3-dione; 4-Amino-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione; Actimid; CC 4047; IMiD 3. Grades: Highly Purified. CAS No. 19171-19-8. Pack Sizes: 500mg, 1g, 5g. Molecular Formula: C??H??N?O?, Molecular Weight: 273.24. US Biological Life Sciences. | Worldwide |
| Pomalidomide-C4-NH2 | Pomalidomide-C4-NH2 is a synthetic E3 ligase ligand-linker conjugate that incorporates Pomalidomide-based CRBN ligands and linkers used in PROTAC technology. Synonyms: 4-((4-aminobutyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione; 4-[(4-Aminobutyl)amino]-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione; 4-[(4-Aminobutyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione; 1H-Isoindole-1,3(2H)-dione, 4-[(4-aminobutyl)amino]-2-(2,6-dioxo-3-piperidinyl)-; Thalidomide-NH-C4-NH2. Grades: ≥95%. CAS No. 1957236-34-8. Molecular formula: C17H20N4O4. Mole weight: 344.37. | |
| Pomalidomide Impurity 6 | An impurity of Pomalidomide which a derivative of thalidomide with antineoplastic effect. Grades: > 95%. Molecular formula: C21H14N4O6. Mole weight: 418.37. | |
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