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| Product | Description | |
|---|---|---|
| 7-Amino-4-methylcoumarin | 7-Amino-4-methylcoumarin belongs to the coumarin class, can be isolated from the endophytic fungus Xylaria sp. and has a broad spectrum of antibacterial activity. 7-Amino-4-methylcoumarin is also commonly used as an important laser dye that emits in the blue region, capable of analyzing glycoprotein monosaccharides and N-linked oligosaccharides, and is also utilized in tissue pathology analysis, enzyme activity measurement, and copper ion detection. The excitation wavelength and emission wavelength are 351 nm and 430 nm, respectively. [1] [2] [3] [4]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Coumarin 120; AMC. CAS No. 26093-31-2. Pack Sizes: 250 mg; 500 mg; 1 g. Product ID: HY-D0027. |  |
| 7-Amino-4-methylcoumarin | 7-Amino-4-methylcoumarin. CAS No. 26093-31-2. Product ID: 9-01547. Molecular formula: C10H9NO2. Mole weight: 175.19. Properties: 6.8 Å. Reference: see also Biochem. J., 89, 59P, 1963. |  |
| 7-Amino-4-methylcoumarin | 7-Amino-4-methylcoumarin. Group: Biochemicals. Grades: Highly Purified. CAS No. 26093-31-2. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C10H9NO2. US Biological Life Sciences. |  Worldwide |
| 7-Amino-4-methylcoumarin | Chromophore for substrates. Group: Fluorescence/luminescence spectroscopy. |  |
| 7-Amino-4-methylcoumarin | λ max 354 nm in EthanolSuitable as laser dye and used as a fluorescent labeling reagent for trace determination of enzymes. Uses: Coumarins are used as laser dyes. coumarin 120 (kodak) is the parent compound of the oldest aminocoumarin laser dye, which is coumarin 311 (kodak). Synonyms: 7-amino-4-methyl-1-benzopyran-2-one; 7-amino-4-methylchromen-2-one. Grades: ≥ 98 % (HPLC). CAS No. 26093-31-2. Molecular formula: C10H9NO2. Mole weight: 175.18. |  |
| 7-Amino-4-methylcoumarin-3-acetic acid | 7-Amino-4-methylcoumarin-3-acetic acid is a fluorescent protein labelling agent. 7-Amino-4-methylcoumarin-3-acetic acid emits in the blue region (440-460 nm) on activation with UV light (350 nm) [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 106562-32-7. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-D0025. | |
| 7-Amino-4-methylcoumarin 99+% (HPLC) | 7-Amino-4-methylcoumarin 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| 7-Amino-4-methylcoumarin (AMC) | 1g Pack Size. Group: Biochemicals, Stains & Indicators. Formula: C10H9NO2. CAS No. 26093-31-2. Prepack ID 22061681-1g. Molecular Weight 175.18. See USA prepack pricing. |  |
| 7-Amino-4-methylcoumarin (AMC) | 5g Pack Size. Group: Biochemicals, Stains & Indicators. Formula: C10H9NO2. CAS No. 26093-31-2. Prepack ID 22061681-5g. Molecular Weight 175.18. See USA prepack pricing. | |
| 7-Amino-4-methylcoumarin - CAS 26093-31-2 | Reagent used to prepare fluorogenic 7-amido-4-methylcoumarin (AMC) based substrates for the detection of proteolytic enzyme activity. Group: Fluorescence/luminescence spectroscopy. | |
| 7-Amino-4-methylcoumarin (Coumarin 120) | 7-Amino-4-methylcoumarin (Coumarin 120). Group: Biochemicals. Alternative Names: Coumarin 120. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| 7-Amino-4-methylcoumarin hydrogensulfate | 7-Amino-4-methylcoumarin hydrogensulfate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 7-AMINO-4-METHYLCOUMARIN HYDROGENSULFATE (SALT);7-AMINO-4-METHYLCOUMARIN HYDROGENSULFATE. Product Category: Heterocyclic Organic Compound. CAS No. 207673-94-7. Molecular formula: C10H11NO6S. Mole weight: 273.26. Product ID: ACM207673947. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Ac-ANW-AMC | Ac-ANW-AMC is a 7-amino-4-methylcoumarin labelled fluorogenic peptidyl substrate and used for measuring chymotrypsin-like activity of the immunoproteasome. Synonyms: (S)-N1-((S)-3-(1H-indol-3-yl)-1-((4-methyl-2-oxo-2H-chromen-7-yl)amino)-1-oxopropan-2-yl)-2-((S)-2-acetamidopropanamido)succinamide; N-Acetyl-L-alanyl-L-asparaginyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-tryptophanamide; Acetyl-Ala-Asn-Trp-7-amido-4-methylcoumarin. Grades: >99%. Molecular formula: C30H32N6O7. Mole weight: 588.61. | |
| Ac-DEVD-AMC | Ac-DEVD-AMC is a fluorogenic substrate for caspase-3. Caspase activity can be quantified by fluorescent detection of free AMC (7-amino-4-methylcoumarin), which is excited at 340-360 nm and emits at 440-460 nm. Synonyms: N-Acetyl-Asp-Glu-Val-Asp-7-amido-4-Methylcoumarin; N-acetyl-L-α-aspartyl-L-α-glutamyl-L-valyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-α-asparagine. Grades: ≥95%. CAS No. 169332-61-0. Molecular formula: C30H37N5O13. Mole weight: 675.64. | |
| Ac-DNLD-AMC | Ac-DNLD-AMC is a fluorogenic substrate for caspase-3. It is cleaved by caspase-3 to release the fluorescent moiety 7-amino-4-methylcoumarin (AMC), which can be used to quantify caspase-3 activity. Synonyms: N-Acetyl-Asp-Asn-Leu-Asp-7-amido-Methylcoumarin; N-acetyl-L-α-aspartyl-L-asparaginyl-L-leucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-α-asparagine. Grades: ≥95%. CAS No. 958001-92-8. Molecular formula: C30H38N6O12. Mole weight: 674.7. | |
| Ac-Nle-Pro-Nle-Asp-AMC | Ac-Nle-Pro-Nle-Asp-AMC is a substrate for proteasomes. It can be cleaved by the caspase-like site of proteasome, also known as postglutamyl peptide hydrolase (PGPH). AMC (7-amino-4-methylcoumarin) is released and produces the fluorescence utilized to quantify the caspase-like site activity. Ac-Nle-Pro-Nle-Asp-AMC also inhibits the chymotrypsin-like activity of the proteasome allosterically when bound to the caspase-like site. Synonyms: Ac-Nle-Pro-Nle-Asp-7-amido-4-Methylcoumarin; Ac-nLPnLD-AMC; N-acetyl-L-norleucyl-L-prolyl-L-norleucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-α-asparagine; L-α-Asparagine, N-acetyl-L-norleucyl-L-prolyl-L-norleucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-; (3S) -4-Hydroxy-3- ({ (2S) -1-hydroxy-2-[ (hydroxy{ (2S) -1-[N- (1-hydroxyethylidene) -L-norleucyl]-2-pyrrolidinyl}methylene) amino]hexylidene}amino) -4-[ (4-methyl-2-oxo-2H-chromen-7-yl) imino]butanoic acid. Grades: ≥98%. CAS No. 355140-49-7. Molecular formula: C33H45N5O9. Mole weight: 655.74. | |
| Ac-PAL-AMC | Ac-PAL-AMC is a fluorogenic substrate for the β1i/LMP2 subunit of the 20S immunoproteasome. It can be cleaved to release the fluorescent moiety 7-amino-4-methylcoumarin (AMC), which can be used to quantify the activity of the β1i/LMP2 subunit of the 20S immunoproteasome. Synonyms: Acetyl-Pro-Ala-Leu-7-amino-4-Methylcoumarin; 1-acetyl-L-prolyl-L-alanyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-leucinamide. Grades: ≥95%. CAS No. 1431362-79-6. Molecular formula: C26H34N4O6. Mole weight: 498.6. | |
| Ac-RLR-AMC trifluoroacetate salt | Ac-RLR-AMC is a fluorogenic substrate for the 26S proteasome. Ac-RLR-AMC is cleaved to release the fluorescent moiety 7-amino-4-methylcoumarin (AMC), which can be used to quantify the trypsin-like activity of 26S proteasomes. Synonyms: Ac-Arg-Leu-Arg-7-amino-4-methylcoumarin; (S)-2-acetamido-5-guanidino-N-((S)-1-(((S)-5-guanidino-1-((4-methyl-2-oxo-2H-chromen-7-yl)amino)-1-oxopentan-2-yl)amino)-4-methyl-1-oxopentan-2-yl)pentanamide, 2,2,2-trifluoroacetate salt. Grades: ≥98%. Molecular formula: C30H46N10O6·CF3COOH. Mole weight: 756.8. | |
| Ac-Trp-Glu-His-Asp-AMC | Synonyms: AC-WEHD-AMC; Acetyl-L-Tryptophyl-L-Glutamyl-L-Histidyl-L-Aspartic Acid Alpha-(4-Methylcoumaryl-7-Amide); Caspase 1 (Ice) Substrate 3M, Fluorogenic; N-Acetyl-Trp-Glu-His-Asp-7-amino-4-methylcoumarin. CAS No. 189275-74-9. Molecular formula: C38H40N8O11. Mole weight: 784.77. | |
| Ac-val-glu-ile-asp-amc | Ac-val-glu-ile-asp-amc. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-ACETYL-VAL-GLU-ILE-ASP-7-AMINO-4-METHYLCOUMARIN AMC;CASPASE-6 SUBSTRATE (FLUOROGENIC);CASPASE-6 SUBSTRATE I, FLUOROGENIC;CASPASE 6 (MCH2) SUBSTRATE 1M, FLUOROGENIC;ACETYL-L-VALYL-L-GLUTAMYL-L-ISOLEUCYL-L-ASPARTIC ACID ALPHA-(4-METHYLCOUMARYL-7-AMIDE);A. Product Category: Heterocyclic Organic Compound. CAS No. 219137-97-0. Molecular formula: C32H43N5O11. Mole weight: 673.71. Product ID: ACM219137970. Alfa Chemistry ISO 9001:2015 Certified. Categories: Ac-VEID-AMC. | |
| Ac-VEID-AMC | Ac-VEID-AMC is a fluorogenic substrate for caspase-6 and related proteases including caspase-8. Caspase activity can be quantified by fluorescent detection of free AMC (7-amino-4-methylcoumarin), which is excited at 340-360 nm and emits at 440-460 nm. Synonyms: N-Acetyl-Val-Glu-Ile-Asp-7-amido-4-Methylcoumarin; N-acetyl-L-valyl-L-α-glutamyl-L-isoleucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-α-asparagine. Grades: ≥95%. CAS No. 219137-97-0. Molecular formula: C32H43N5O11. Mole weight: 673.7. | |
| Ac-WLA-AMC | Ac-WLA-AMC is a fluorogenic substrate for the β5c subunit of the 20S proteasome. Ac-WLA-AMC is cleaved to release the fluorescent moiety 7-amino-4-methylcoumarin (AMC), which can be used to quantify the β5c subunit activity. Synonyms: Acetyl-Trp-Leu-Ala-7-amino-4-Methylcoumarin; N-acetyl-L-tryptophyl-L-leucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-alaninamide. Grades: ≥95%. CAS No. 1104011-59-7. Molecular formula: C32H37N5O6. Mole weight: 587.7. | |
| AMC | AMC. Group: other materials. Alternative Names: 7-Amino-4-methylcoumarin. CAS No. 26093-31-2. Product ID: 7-amino-4-methylchromen-2-one. Molecular formula: 175.18g/mol. Mole weight: C10H9NO2. CC1=CC(=O)OC2=C1C=CC(=C2)N. InChI=1S/C10H9NO2/c1-6-4-10 (12)13-9-5-7 (11)2-3-8 (6)9/h2-5H, 11H2, 1H3. GLNDAGDHSLMOKX-UHFFFAOYSA-N. |  |
| AMCA-X | AMCA-X. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 6-((7-Amino-4-methylcoumarin-3-acetyl)amino)hexanoicacid. Product Category: Other Fluorophores. Appearance: Solid. CAS No. 205124-69-2. Molecular formula: C18H22N2O5. Mole weight: 346.38. Purity: 95%+. IUPACName: 6-[[2-(7-amino-4-methyl-2-oxochromen-3-yl)acetyl]amino]hexanoicacid. Canonical SMILES: CC1=C(C(=O)OC2=C1C=CC(=C2)N)CC(=O)NCCCCCC(=O)O. Density: 1.270 ± 0.06 g/ml. Product ID: ACM205124692-1. Alfa Chemistry ISO 9001:2015 Certified. Categories: AMC AMX. | |
| Beta-Ala-Lys-AMCA | Fluorescent dipeptide derivative, which could be used as an excellent reporter molecule for studying the oligopeptide transport system in brain cell cultures. Group: Biochemicals. Alternative Names: b-Ala-(L)-Lys-N-7-amino-4-methylcoumarin-3-acetic acid; b-Ala-Lys-Nε-AMCA; ß-Ala-Lys-Nε-AMCA; β-Alanyl-Nε-(7-Amino-4-Methyl-2-Oxo-2H-1-Benzopyran-3-Acetyl)-L-Lysine. Grades: Highly Purified. Pack Sizes: 1mg, 5mg. Molecular Formula: C21H28N4O6, Molecular Weight: 432.47. US Biological Life Sciences. | Worldwide |
| Boc-ile-glu-gly-arg-7-amido-4-methylcoumarin acetate salt | Boc-ile-glu-gly-arg-7-amido-4-methylcoumarin acetate salt. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Biggam, Boc-ile-glu-gly-arg-mca, CID196426, tertiary-Butyloxycarbonyl-isoleucyl-glutamyl-glycyl-arginyl-7-amino-4-methylcoumarin, 65147-06-0, L-Argininamide, N-((1,1-dimethylethoxy)carbonyl)-L-isoleucyl-L-alpha-glutamylglycyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-. Appearance: WHITE POWDER. CAS No. 65147-06-0. Molecular formula: C34H50N8O10. Mole weight: 730.81. Purity: 95%+. IUPACName: (4S)-5-[[2-[[(2S)-5-(diaminomethylideneamino)-2-[(4-methyl-2-oxochromen-7-yl)amino]pentanoyl]amino]-2-oxoethyl]amino]-4-[[(2S,3S)-3-methyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoyl]amino]-5-oxopentanoic acid. Canonical SMILES: CCC(C)C(C(=O)NC(CCC(=O)O)C(=O)NCC(=O)NC(=O)C(CCCN=C(N)N)NC1=CC2=C(C=C1)C(=CC(=O)O2)C)NC(=O)OC(C)(C)C. Density: 1.36 g/cm³. Product ID: ACM65147060. Alfa Chemistry ISO 9001:2015 Certified. Categories: Boc-Ile-Glu-Gly-Arg-AMC. | |
| H-Gly-amc | H-Gly-amc. Uses: Designed for use in research and industrial production. Additional or Alternative Names: L-Gly-AMC, L-Gly-7-Amino-4-Methylcoumarin, L-G-AMC, 77471-42-2, 2-Amino-N-(4-methyl-2-oxo-2H-chromen-7-yl)acetamide, AmbotzHAA7970, AC1LEM62, SCHEMBL790969, AMC004, MolPort-008-268-104, KM1858, AKOS022186047, AJ-09671, AK144290, DA-03426, ST24039983, 2-amino-N-(4-methyl-2-oxochromen-7-yl)acetamide, 2-amino-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)Acetamide. Product Category: Heterocyclic Organic Compound. CAS No. 77471-42-2. Molecular formula: C12H12N2O3. Mole weight: 232.24. Purity: 0.96. IUPACName: 2-amino-N-(4-methyl-2-oxochromen-7-yl)acetamide. Product ID: ACM77471422. Alfa Chemistry ISO 9001:2015 Certified. | |
| L-a-Asparagine,N-acetyl-L-tyrosyl-L-valyl-L-alanyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-(9ci) | L-a-Asparagine,N-acetyl-L-tyrosyl-L-valyl-L-alanyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-(9ci). Uses: Designed for use in research and industrial production. Additional or Alternative Names: Acetyl-YVAD-AMC, Ac-YVAD-AMC, Ac-Tyr-Val-Ala-Asp-AMC, A2452_SIGMA, AMC120, CID4337, CID 4337, ICE (CASPASE I) SUBSTRATE III, Ac-Tyr-Val-Ala-Asp-7-Amino-4-Methylcoumarin, IL-1 beta Converting Enzyme Fluorogenic Substrate, N-Acetyl-Tyr-Val-Ala-Asp-7-amido-4-methylcoumarin, 149231-65-2. Product Category: Heterocyclic Organic Compound. Appearance: white powder. CAS No. 149231-65-2. Molecular formula: C33H39N5O10. Mole weight: 665.6903. Purity: 0.96. IUPACName: 3-[2-[[2-[[2-acetamido-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]propanoylamino]-4-[(4-methyl-2-oxochromen-7-yl)amino]-4-oxobutanoic acid. Canonical SMILES: CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)C(CC(=O)O)NC(=O)C(C)NC(=O)C(C(C)C)NC(=O)C(CC3=CC=C(C=C3)O)NC(=O)C. Density: 1.344 g/cm³. Product ID: ACM149231652. Alfa Chemistry ISO 9001:2015 Certified. | |
| L-Alanine-7-amido-4-methylcoumarin hydrochloride 99+% (L-Ala-AMC·HCl) | L-Leucine 7-Amido-4-methylcoumarin Hydrochloride is a fluorogenic substrate for LAP3 (leucine aminopeptidase). Upon enzyme activity, a bright blue fluorescent dye, 7-amino-4-methylcoumarin, is released. Group: Biochemicals. Alternative Names: L-Ala-AMC·HCl. Grades: Highly Purified. CAS No. 62480-44-8. Pack Sizes: 100mg, 250mg, 1g. Molecular Formula: C13H14N2O3·HCl, Molecular Weight: 282.6. US Biological Life Sciences. | Worldwide |
| Leu-AMC HCl | L-Leucine 7-Amido-4-methylcoumarin Hydrochloride is a fluorogenic substrate for LAP3 (leucine aminopeptidase). Upon enzyme activity, a bright blue fluorescent dye, 7-amino-4-methylcoumarin, is released. Synonyms: L-Leucine-AMC.HCl. Grades: ≥ 99% (HPLC). CAS No. 62480-44-8. Molecular formula: C16H21ClN2O3. Mole weight: 324.80. | |
| L-Isoleucine 7-amido-4-methylcoumarin | Synonyms: L-Ile-AMC; L-ILE-7-AMINO-4-METHYLCOUMARIN; ISOLEUCINE-AMC; H-Ile-AMC Trifluoroacetate salt; L-ISOLEUCINE 7-AMIDO-4-METHYLCOUMARIN. Grades: ≥ 98% (HPLC). CAS No. 98516-74-6. Molecular formula: C16H20N2O3. Mole weight: 288.36. | |
| MeOSuc-Ala-Ala-Pro-Met-AMC | MeOSuc-Ala-Ala-Pro-Met-AMC is a fluorogenic substrate for cathepsin G. Synonyms: MeOSuc-Ala-Ala-Pro-Met-7-Amino-4-Methylcoumarin. CAS No. 201853-55-6. Molecular formula: C31H41N5O9S. Mole weight: 659.75. | |
| MeoSuc-Ala-Ala-Pro-Val-AMC | MeOSuc-AAPV-AMC is a fluorogenic substrate for human leukocyte and porcine pancreatic elastase. The methoxy succinyl (MeO-Suc) peptide AAPV is hydrolyzed by these elastases but not by cathepsin G. The addition of 7-amino-4-methylcoumarin (AMC) generates a peptide of low fluorescence (excitation: 355-380 nm; emission 440-460 nm) that demonstrates a linear increase in fluorescence intensity in the presence of elastase. Synonyms: MeOSuc-AAPV-AMC;I 1270; Methoxy Succinyl-Ala-Ala-Pro-Val-AMC; N-(4-methoxy-1,4-dioxobutyl)-L-alanyl-L-alanyl-L-prolyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-valinamide. Grades: ≥95% by HPLC. CAS No. 72252-90-5. Molecular formula: C31H41N5O9. Mole weight: 627.7. | |
| SUC-ALA-ALA-ALA-AMC | A sensitive fluorogenic substrate for pancreatic elastase. Synonyms: Suc-Ala-Ala-Ala-7-Amino-4-Methylcoumarin; succinyl-Ala-Ala-Ala-4-methylcoumaryl-7-amide; 4-((S)-1-((S)-1-((S)-1-(4-methyl-2-oxo-2H-chromen-7-ylamino)-1-oxopropan-2-ylamino)-1-oxopropan-2-ylamino)-1-oxopropan-2-ylamino)-4-oxobutanoic acid. CAS No. 73617-90-0. Molecular formula: C23H28N4O8. Mole weight: 488.49. | |
| Z-LLE-AMC | Z-LLE-AMC is a fluorogenic substrate for the caspase-like post-glutamate peptide hydrolase of the 26S proteasome or 20S proteolytic core. AMC (7-amino-4-methylcoumarin) is released to quantify the caspase-like hydrolase activity. Synonyms: Proteasome Substrate III, Fluorogenic. Grades: >95%. CAS No. 348086-66-8. Molecular formula: C35H44N4O9. Mole weight: 664.76. | |
| 7-Azido-4-methylcoumarin (AzMC) | Highly sensitive and selective fluorogenic H2S probe. The aromatic azide moiety of AzMC is selectively reduced in the presence of H2S, producing the fluorescent 7-amino-4- methylcoumarin (AMC) with a concomitant increase in fluorescence with lambdaex=365nm and lambdaem=450nm. Photoaffinity labeling probe for the substrate binding site of human sulfotransferase 1A1 (SULT1A1). Probe to monitor the enzymatic production of H2S in vitro and to visualize H2S in living cells. Tool for monitoring the activity of pyridoxal-5'-phosphate (PLP)-dependent enzymes (e.g. cystathionine beta-synthase (CBS), cystathionine gamma-lyase (CGL) and tryptophan synthase (TS)). Tool to identify novel cystathionine beta-synthase (CBS) inhibitors and activators. Suitable for high-throughput screening. Use of this product with DTT, TCEP and/or biological thiols at concentrations of >25mM should be avoided for maximum efficiency. Group: Biochemicals. Grades: Highly Purified. CAS No. 95633-27-5. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
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