Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
| Product | Description | |
|---|---|---|
| 2-Methyl-1-hexene | Liquid, d20 0.70, 99%. CAS No. 6094-2-6. Pack Sizes: 5g, 25g. Product ID: FR-2700. B.P. 92. Mole weight: 98.19. |  Frinton Laboratories |
| 4,5-Dichlorophthalic anhydride | 4,5-Dichlorophthalic anhydride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AKOS 92355;5,6-DICHLORO-1,3-DIHYDROISOBENZOFURAN-1,3-DIONE;4,5-DICHLOROPHTHALIC ANHYDRIDE;5,6-Dichloro-2-benzofuran-1,3-dione;4,5-DICHLOROPHTHALIC ANHYDRIDE 98+%;5,6-Dichloroisobenzofuran-1,3(1H,3H)-dione;4,5-Dichlorophalicanhydride;5,6-Dichloroisobenzofu. Product Category: Polymer/Macromolecule. Appearance: Light grey to pale blue powder. CAS No. 942-06-3. Molecular formula: C8H2Cl2O3. Mole weight: 217.01. Purity: 0.96. IUPACName: 5,6-dichloro-2-benzofuran-1,3-dione. Canonical SMILES: C1=C2C(=CC(=C1Cl)Cl)C(=O)OC2=O. Density: 1.715g/cm³. ECNumber: 213-386-2. Product ID: ACM942063. Alfa Chemistry ISO 9001:2015 Certified. |  |
| 5-Hexyn-1-Ol | 5-Hexyn-1-Ol. Uses: Designed for use in research and industrial production. Product Category: Alkynes. CAS No. 928-90-5. Molecular formula: C6H10O. Mole weight: 98.14. Purity: 0.97. Canonical SMILES: C#CCCCCO. Product ID: ACM928905. Alfa Chemistry ISO 9001:2015 Certified. | |
| AKI-001 | AKI-001 is a potent Aurora kinase inhibitor, which exhibits low nanomolar potency against both Aurora A and Aurora B enzymes, excellent cellular potency (IC50 < 100 nM), and good oral bioavailability. Synonyms: AKI-001; AKI 001; AKI001. Grades:>98%. CAS No. 925218-37-7. Molecular formula: C21H24N4O. Mole weight: 348.45. |  |
| Barium dihexacosanoate | Barium dihexacosanoate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Barium dihexacosanoate, 98978-64-4, CTK5I0150, EINECS 308-896-8, AG-I-00697. Product Category: Heterocyclic Organic Compound. CAS No. 98978-64-4. Molecular formula: C52H102BaO4. Mole weight: 928.690880 [g/mol]. Purity: 0.96. IUPACName: barium(2+);hexacosanoate. Product ID: ACM98978644. Alfa Chemistry ISO 9001:2015 Certified. | |
| bpV(phen) potassium hydrate | BpV(phen) is a bisperoxovanadium (bpV) compound which inhibits several different protein tyrosine phosphatases (PTPs) with IC50 of 38 nM. It also inhibits the vascular endothelial PTP-β with IC50 of 343 nM and PTP-1β with IC50 of 920 nM. At 0.1 mM, bpV(phen) inhibits SH2 domain-containing inositol 5'-phosphatase-2. Presumably by inhibiting insulin receptor kinase-associated PTPs, bpV(phen) activates the insulin receptor tyrosine kinase and promotes downstream signaling, including activation of PI3-kinase. Synonyms: Bisperoxovanadium(phen); Potassium Bisperoxo(1,10-phenanthroline) oxovanadate (V). Grades: ≥98%. CAS No. 171202-16-7. Molecular formula: C12H8N2O5V·K+(H2O)3. Mole weight: 404.3. | |
| Chitosan (200-600mPa·s, 0.5% in 0.5% Acetic Acid at 20°C) | Solid. Group: Polymers. CAS No. 9012-76-4. Product ID: methyl N-[(2S,3R,4R,5S,6R)-5-[(2S,3R,4R,5S,6R)-3-amino-5-[(2S,3R,4R,5S,6R)-3-amino-5-[(2S,3R,4R,5S,6R)-3-amino-5-[(2S,3R,4R,5S,6R)-3-amino-5-[(2S,3R,4R,5S,6R)-3-amino-5-[(2S,3R,4R,5S,6R)-3-amino-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-[(2R,3S,4R,5R,6S)-5-amino-6-[(2R,3S,4R,5R,6R)-5-amino-4,6-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-4-hydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-4-hydroxy-6-(hydroxymethyl)oxan-3-yl]carbamate. Molecular formula: 1526.5g/mol. Mole weight: C56H103N9O39. COC (=O)NC1C (C (C (OC1OC2C (OC (C (C2O)N)OC3C (OC (C (C3O)N)O)CO)CO)CO)OC4C (C (C (C (O4)CO)OC5C (C (C (C (O5)CO)OC6C (C (C (C (O6)CO)OC7C (C (C (C (O7)CO)OC8C (C (C (C (O8)CO)OC9C (C (C (C (O9)CO)O)O)N)O)N)O)N)O)N)O)N)O)N)O. InChI=1S/C56H103N9O39/c1-87-56 (86)65-28-38 (84)46 (19 (10-74)96-55 (28)104-45-18 (9-73)95-49 (27 (64)37 (45)83)97-39-12 (3-67)88-47 (85)20 (57)31 (39)77)103-54-26 (63)36 (82)44 (17 (8-72)94-54)102-53-25 (62)35 (81)43 (16 (7-71)93-53)101-52-24 (61)34 (80)42 (15 (6-70)92-52)100-51-23 (60)33 (79)41 (14 (5-69)91-51)99-50-22 (59)32 (78)40 (13 (4-68)90-50)98-48-21 (58)30 (76)29 (75)11 (2-66)89-48/h11-55, 66-85H, 2-10, 57-64H2, 1 |  |
| Chitosan (20-100mPa·s, 0.5% in 0.5% Acetic Acid at 20°C) | Solid. Group: Polymers. CAS No. 9012-76-4. Product ID: methyl N-[(2S,3R,4R,5S,6R)-5-[(2S,3R,4R,5S,6R)-3-amino-5-[(2S,3R,4R,5S,6R)-3-amino-5-[(2S,3R,4R,5S,6R)-3-amino-5-[(2S,3R,4R,5S,6R)-3-amino-5-[(2S,3R,4R,5S,6R)-3-amino-5-[(2S,3R,4R,5S,6R)-3-amino-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-[(2R,3S,4R,5R,6S)-5-amino-6-[(2R,3S,4R,5R,6R)-5-amino-4,6-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-4-hydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-4-hydroxy-6-(hydroxymethyl)oxan-3-yl]carbamate. Molecular formula: 1526.5g/mol. Mole weight: C56H103N9O39. COC (=O)NC1C (C (C (OC1OC2C (OC (C (C2O)N)OC3C (OC (C (C3O)N)O)CO)CO)CO)OC4C (C (C (C (O4)CO)OC5C (C (C (C (O5)CO)OC6C (C (C (C (O6)CO)OC7C (C (C (C (O7)CO)OC8C (C (C (C (O8)CO)OC9C (C (C (C (O9)CO)O)O)N)O)N)O)N)O)N)O)N)O)N)O. InChI=1S/C56H103N9O39/c1-87-56 (86)65-28-38 (84)46 (19 (10-74)96-55 (28)104-45-18 (9-73)95-49 (27 (64)37 (45)83)97-39-12 (3-67)88-47 (85)20 (57)31 (39)77)103-54-26 (63)36 (82)44 (17 (8-72)94-54)102-53-25 (62)35 (81)43 (16 (7-71)93-53)101-52-24 (61)34 (80)42 (15 (6-70)92-52)100-51-23 (60)33 (79)41 (14 (5-69)91-51)99-50-22 (59)32 (78)40 (13 (4-68)90-50)98-48-21 (58)30 (76)29 (75)11 (2-66)89-48/h11-55, 66-85H, 2-10, 57-64H2, 1H | |
| Chitosan (5-20mPa·s, 0.5% in 0.5% Acetic Acid at 20°C) | Solid. Group: Polymers. CAS No. 9012-76-4. Product ID: methyl N-[(2S,3R,4R,5S,6R)-5-[(2S,3R,4R,5S,6R)-3-amino-5-[(2S,3R,4R,5S,6R)-3-amino-5-[(2S,3R,4R,5S,6R)-3-amino-5-[(2S,3R,4R,5S,6R)-3-amino-5-[(2S,3R,4R,5S,6R)-3-amino-5-[(2S,3R,4R,5S,6R)-3-amino-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-[(2R,3S,4R,5R,6S)-5-amino-6-[(2R,3S,4R,5R,6R)-5-amino-4,6-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-4-hydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-4-hydroxy-6-(hydroxymethyl)oxan-3-yl]carbamate. Molecular formula: 1526.5g/mol. Mole weight: C56H103N9O39. COC (=O)NC1C (C (C (OC1OC2C (OC (C (C2O)N)OC3C (OC (C (C3O)N)O)CO)CO)CO)OC4C (C (C (C (O4)CO)OC5C (C (C (C (O5)CO)OC6C (C (C (C (O6)CO)OC7C (C (C (C (O7)CO)OC8C (C (C (C (O8)CO)OC9C (C (C (C (O9)CO)O)O)N)O)N)O)N)O)N)O)N)O)N)O. InChI=1S/C56H103N9O39/c1-87-56 (86)65-28-38 (84)46 (19 (10-74)96-55 (28)104-45-18 (9-73)95-49 (27 (64)37 (45)83)97-39-12 (3-67)88-47 (85)20 (57)31 (39)77)103-54-26 (63)36 (82)44 (17 (8-72)94-54)102-53-25 (62)35 (81)43 (16 (7-71)93-53)101-52-24 (61)34 (80)42 (15 (6-70)92-52)100-51-23 (60)33 (79)41 (14 (5-69)91-51)99-50-22 (59)32 (78)40 (13 (4-68)90-50)98-48-21 (58)30 (76)29 (75)11 (2-66)89-48/h11-55, 66-85H, 2-10, 57-64H2, 1H3, | |
| cis-3-Hexen-1-ol | Clear liquid, 98%, d25 0.85, ~8% trans. CAS No. 928-96-1. Pack Sizes: 50g, 250g. Product ID: FR-0228. B.P. 156-157. Mole weight: 100.16. | Frinton Laboratories |
| DB07268 | DB07268 is a potent and selective JNK1 inhibitor. It has some degree of selectivity over quite a few kinases with the exceptions of CHK1, CK2, and PLK. Synonyms: DB07268; DB-07268; DB 07268. Grades: >98%. CAS No. 929007-72-7. Molecular formula: C17H15N5O2. Mole weight: 321.33. | |
| DPPE | DPPE (1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine), a glycerophosphonoethanolamine family member, is used in the model membrane. Synonyms: 16:0 PE; 1,2-Dipalmitoyl-sn-glycero-3-PE; 1,2-Dipalmitoyl-sn-glycerol-3-Phosphoethanolamine; 1,2-DPPE. Grades: ≥98%. CAS No. 923-61-5. Molecular formula: C37H74NO8P. Mole weight: 691.96. | |
| GK921 | GK921 is a transglutaminase 2 (TGase 2) inhibitor with average GI50 of 0.9 μM in cancer cell lines. Synonyms: GK921; GK-921; GK 921. Grades: >98%. CAS No. 1025015-40-0. Molecular formula: C21H20N4O. Mole weight: 344.41. | |
| HBX 41108 | HBX 41108 is an inhibitor of ubiquitin-specific protease (USP) 7 (IC50 = 424 nM). HBX 41108 inhibits USP7-mediated p53 deubiquitination (IC50 = 0.8 μM). HBX 41108 stabilizes p53, activates transcription of a p53 target gene without inducing genotoxic stress, and inhibits cancer cell growth. HBX 41108 induces p53-dependent apoptosis in p53 wild type and null isogenic cancer cell lines. Synonyms: HBX 41108; HBX-41108; HBX41108; HBX 41,108; HBX-41,108; HBX41,108. 7-Chloro-9-oxo-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile. Grades: ≥98% by HPLC. CAS No. 924296-39-9. Molecular formula: C13H3ClN4O. Mole weight: 266.64. | |
| MK-5172 hydrate | In biochemical assays, MK-5172 was effective against a panel of major genotypes and variants engineered with common resistant mutations observed in clinical studies with other NS3/4a protease inhibitors. In the replicon assay, MK-5172 demonstrated subnanomolar to low-nanomolar EC50s against genotypes 1a, 1b, and 2a. In rats, MK-5172 showed a plasma clearance of 28 ml/min/kg and plasma half-life of 1.4 hr. When dosed p.o. at 5 mg/kg, the plasma exposure of MK-5172 was good with an AUC of 0.7 uM.hr. The liver exposure of the compound was quite good (23 uM at 4 hr), and MK-5172 remained in liver 24 hr after a single p.o. 5 mg/kg dose. At 24 hr, the liver concentration of MK-5172 was 0.2 uM, which was over 25-fold higher than the IC50 in the replicon assay with 50% NHS. When dosed to dogs, MK-5172 showed low clearance of 5 ml/min/kg and a 3 hr half-life after i.v. 2 mg/kg dosing and had good plasma exposure (AUC=0.4 uM.hr) after a p.o. 1 mg/kg dose. Uses: Antiviral agents. Synonyms: (33R,35S,91R,92R,5S)-5-(tert-butyl)-N-((1R,2S)-1-((cyclopropylsulfonyl)carbamoyl)-2-vinylcyclopropyl)-17-methoxy-4,7-dioxo-2,8-dioxa-6-aza-1(2,3)-quinoxalina-3(3,1)-pyrrolidina-9(1,2)-cyclopropanacyclotetradecaphane-35-carboxamide hydrate; MK-5172; MK 5172; MK5172; Grazoprevir; Grazoprevir hydrate; trade name: Zepatier?. Grades: >98%. CAS No. 1350462-55-3. Molecular formula: C38H52N6O10S. Mole weight: 784.92. | |
| ML352 | ML352 is a potent and non-competitive inhibitor of the presynaptic choline transporter (CHT; Ki value 92 nM). Synonyms: ML352; ML-352; ML 352; VU0476201; VU-0476201; VU 0476201; VU0476328; VU-0476328; VU 0476328; N-((3-Isopropylisoxazol-5-yl)methyl)-4-methoxy-3-((1-methylpiperidin-4-yl)oxy)benzamide; 4-methoxy-3-(1-methylpiperidin-4-yl)oxy-N-[(3-propan-2-yl-1,2-oxazol-5-yl)methyl]benzamide. Grades: 98%. CAS No. 1649450-12-3. Molecular formula: C21H29N3O4. Mole weight: 387.47. | |
| MRT-92 HCl salt | MRT-92 is a selective Smoothened (Smo) receptor inhibitor. It shows subnanomolar antagonist activity against Smo in various Hh cell-based assays. MRT-92 inhibits rodent cerebellar granule cell proliferation induced by Hh pathway activation through pharmacologic (IC50 value is 0.4 nM) or genetic manipulation. Smo is the target of anticancer drugs, so MRT-92 may be become a drug candidate for treatment of cancer. Uses: Cancer. Synonyms: MRT-92 HCl salt; MRT 92 HCl salt; MRT92 HCl salt; 3, 4, 5-trimethoxy-N- (N- (4-methyl-3- (4-phenethylbenzamido) phenyl) carbamimidoyl) benzamide hydrochloride. Grades: 98%. CAS No. 1428307-52-1. Molecular formula: C33H35ClN4O5. Mole weight: 603.13. | |
| NBQX | This active molecular is an AMPA receptor antagonist which blocks AMPA receptors in 10-20μM concentrations. It is also a Glutamate receptor antagonist. NBQX was found to have anticonvulsant activity in rodent seizure models. This compound has neuroprotective properties. In Nov 1995, NBQX was discontinued preclinical for Stroke in Denmark and in United Kingdom. In Nov 1997, NBQX was discontinued preclinical for Parkinson's disease in USA. Uses: A potent and discriminating antagonist for ampa binding sites. this compound has neuroprotective properties. Synonyms: 6-nitro-2,3-dioxo-1,4-dihydrobenzo[f]quinoxaline-7-sulfonamide; NNC 079202; FG 9202; NNC079202; FG9202; NNC-079202; FG-9202. Grades: 98%. CAS No. 118876-58-7. Molecular formula: C12H8N4O6S. Mole weight: 336.28. | |
| PF-3716556 | PF 3716556 is a potent and selective P-CAB with pIC50 of 6.026 and 7.095 for the inhibition of porcine H+,K+-ATPase activity in ion-leaky and ion-tight assay, respectively, inhibits gastric acid secretion, displays no activity at Na+,K+-ATPase, used for the treatment of gastroesophageal reflux disease. Synonyms: PF-03716556; PF 03716556; PF03716556; PF-3716556; PF 3716556; PF3716556. Grades: >98%. CAS No. 928774-43-0. Molecular formula: C22H26N4O3. Mole weight: 394.47. | |
| Pipendoxifene | Pipendoxifene, also known as ERA-923, is a new antiestrogen with potential anticancer activity. ERA-923 potently inhibits estrogen binding to ER-alpha (IC50=14 nM). In ER-alpha-positive human MCF-7 breast carcinoma cells, ERA-923 inhibits estrogen-stimulated growth (IC50=0.2 nM) associated with cytostasis. In vitro, a MCF-7 variant with inherent resistance to tamoxifen (10-fold) or 4-OH tamoxifen (>1000-fold) retains complete sensitivity to ERA-923. In preclinical models, ERA-923 has an improved efficacy and safety compared with tamoxifen. In the combination with temsirolimus, ERA-923 showed excellent anticancer activity in preclinical models. Synonyms: ERA-923; ERA 923; ERA923; 2-(p-Hydroxyphenyl)-3-methyl-1-(p-(2-piperidinoethoxy)benzyl)indol-5-ol. Grades: >98%. CAS No. 198480-55-6. Molecular formula: C29H32N2O3. Mole weight: 456.58. | |
| Quercetin | Quercetin is a flavonoid found in galangal and is used as an antitumor agent that induces apoptosis of cancer cells. It acts as a PI 3-kinase and protein kinase C (PKC) inhibitor, and inhibits tyrosine protein kinase, phospholipase A2, phosphodiesterases and mitochondrial ATPase. It also suppresses Ca2+ and K+ channels, and activates GPR30. Quercetin has antioxidant, antiviral and anti-inflammatory effects, and it can be used in cosmetics material. Synonyms: Sophoretin; Meletin; Xanthaurine; Quercetine; 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-; 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one; Flavone, 3,3',4',5,7-pentahydroxy-; Flavone, 3,4',5,5',7-pentahydroxy-; 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-benzopyran-4-one; 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one; 3,3',4',5,7-Pentahydroxyflavone; 3,5,7,3',4'-Pentahydroxyflavone; 3,5,7-Trihydroxy-2-(3,4-dihydroxyphenyl)-4H-chromen-4-one; 3'-Hydroxykaempferol; C.I. 75670; Corvitin; Cyanidelonon 1522; Korvitin; LDN 0052529; Lipoflavon; NSC 57655; NSC 9219; Quercetol; Quercevita; Quertin; Quertine; TCM 5280343. Grades: >98%. CAS No. 117-39-5. Molecular formula: C15H10O7. Mole weight: 302.24. | |
| Sirolimus (Rapamycin) | Sirolimus, also known as rapamycin, is a natural macrocyclic lactone produced by the bacterium Streptomyces hygroscopicus, with immunosuppressant properties. In cells, sirolimus binds to the immunophilin FK Binding Protein-12 (FKBP-12) to generate an immunosuppressive complex that binds to and inhibits the activation of the mammalian Target Of Rapamycin (mTOR), a key regulatory kinase. This results in inhibition of T lymphocyte activation and proliferation that occurs in response to antigenic and cytokine (IL-2, IL-4, and IL-15) stimulation and inhibition of antibody production. Uses: Designed for use in research and industrial production. Additional or Alternative Names: RAPA; RAP; RPM; SLM; AY 22989; AY22989; AY-22989; SILA 9268A; WY090217; WY-090217; WY 090217; C07909; D00753; sirolimus; rapamycin; Rapamune. Product Category: Others. Appearance: White to off-white solid powder. CAS No. 53123-88-9. Molecular formula: C51H79NO13. Mole weight: 914.17. Purity: >98%. IUPACName: (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34, 34a-hexadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido[2,1-c][1,4] oxaazacyclohentriacontine-1,5,11,28,29 (4H,6H,31H)-pentone. Canonical SMILES: C[C@@H](C([C@H](OC)[C@H](O)/C(C)=C/[C@@H](C)C(C[C@@H]([C@H](C)C[C@@H]1CC[C@@H](O)C(OC)C1 | |
| TASP 0433864 | TASP 0433864 is a selective and positive allosteric modulator of mGlu2 receptor (EC50 = 199 and 206 nM for human and rat receptors, respectively) with no agonist activity at rat mGlu2 receptors. It displays weak activity against a range of neurotransmitter targets except 5-HT2B and MAO-B (72 and 92% inhibition at 10 μM, respectively). Synonyms: TASP0433864, TASP0433864, TASP0433864; (2S)-2-[[4-(1,1-Dimethylethyl)phenoxy]methyl]-2,3-dihydro-5-methylimidazo[2,1-b]oxazole-6-carboxamide. Grades: ≥98% by HPLC. CAS No. 1431980-60-7. Molecular formula: C18H23N3O3. Mole weight: 329.39. | |
| t-Butyl pentafluoropropionate | t-Butyl pentafluoropropionate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: tert-Butyl pentafluoropropionate, tert-butyl 2,2,3,3,3-pentafluoropropanoate, 55258-28-1, ZINC02565724, AC1MCMZ4, CTK5A3302, MolPort-001-773-667, PC3772, SBB095890, tert-Butyl pentafluoropropionate 98%, AKOS015852653, AG-C-27612, AG-F-92984, FT-0676793, I14-29265. Product Category: Heterocyclic Organic Compound. CAS No. 55258-28-1. Molecular formula: C7H9F5O2. Mole weight: 220.14. Purity: 0.96. IUPACName: tert-butyl 2,2,3,3,3-pentafluoropropanoate. Canonical SMILES: CC(C)(C)OC(=O)C(C(F)(F)F)(F)F. Density: 1.258g/cm³. Product ID: ACM55258281. Alfa Chemistry ISO 9001:2015 Certified. | |
| TFC 007 | TFC-007 is a selective inhibitor of hematopoietic prostaglandin D synthase (H-PGDS), with high inhibitory activity against the H-PGDS enzyme (IC50 value of 83 nM). TFC-007 can be used to construct a H-PGDS degrader inducer PROTAC(H-PGDS)-1, where TFC-007 binds to H-PGDS and Pomalidomide binds to cereblon. Synonyms: TFC-007; TFC 007; TFC007; N-[4-[4-(4-Morpholinylcarbonyl)-1-piperidinyl]phenyl]-2-phenoxy-5-pyrimidinecarboxamide. Grades: ≥98% by HPLC. CAS No. 927878-49-7. Molecular formula: C27H29N5O4. Mole weight: 487.55. | |
| Troglitazone | Troglitazone, PPARγ agonist, is an anti-diabetic thiazolidinedione (TZD) with anti-inflammatory and anti-tumor activity, which was approved for the treatment of insulin resistance and hyperglycemia in Type II diabetes, but was withdrawn from the market due to hepatotoxicity. It binds to the PPARγ ligand-binding domain (LBD) but fails to induce interaction of the PPARγ LBD with the transcriptional coactivators SRC-1, TIF2, AIB1, p300, or TRAP220. It also induces cell cycle arrest and apoptosis in several cancer cell lines. It displays no activity at PPARα or PPARδ receptors and displays anti-invasive effect on human breast cancer cells. It also inhibits cell growth of hematopoietic cell lines and inhibits lamellipodia formation and actin polymerization. Uses: Hypoglycemic agents. Synonyms: CI-991; CI991; CI 991; CS-045; CS 045; CS045; GR 92132X; GR92132X; Prelay; Troglitazone; Rezulin, Resulin, Romozin, Noscal. Grades: >98%. CAS No. 97322-87-7. Molecular formula: C24H27NO5S. Mole weight: 441.54. | |
| Xanomeline oxalate | Muscarinic receptors are G protein-coupled acetylcholine receptors that play diverse roles. Xanomeline oxalate is a potent agonist of muscarinic acetylcholine receptors (EC50 values are 0.3, 92.5, 5, 52, and 42 nM for M1, M2, M3, M4, and M5, respectively). It has antipsychotic-like activities in rats and Cebus monkeys. M1 selective agonists, like Xanomeline oxalate, enhance memory function and has utility in treating Alzheimer's Disease. Synonyms: LY246708; LY 246708; LY-246708; Memcor; Lumeron. Grades: >98%. CAS No. 141064-23-5. Molecular formula: C16H25N3O5S. Mole weight: 371.45. | |
Our database is helping our users find suppliers everyday.
