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| Product | Description | |
|---|---|---|
| Acetyl Butyryl | Acetyl Butyryl (2,3-Hexanedione). CAS No. 3848-24-6. FEMA No. 2558. Kosher: Y. VIGON Item # 500535. Categories: Speciality Ingredients Suppliers, Flavors, Fragrances, Perfumers. |  America & Internationally |
| 1- (4-Methylbenzyl) piperazine | 1- (4-Methylbenzyl) piperazine is a useful synthetic intermediate in the synthesis of 3-Desmethyl 4-Methyl Meclizine Dihydrochloride (D291930); a metabolite of Meclizine (M202700, 2HCl monohydrate) which is an antiemetic. 1- (4-Methylbenzyl) piperazine is also used in the synthesis of inhibitors of acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE). Group: Biochemicals. Grades: Highly Purified. CAS No. 23173-57-1. Pack Sizes: 1g, 5g. Molecular Formula: C12H18N2, Molecular Weight: 190.28. US Biological Life Sciences. |  Worldwide |
| 2-Methoxythiophenol | 2-Methoxythiophenol is used in the synthesis of berberine-thiophenyl hybrids as multifunctional agents. Inhibition of acetylcholinesterase, butyrylcholinesterase and AB aggregation antioxidant activity. Group: Biochemicals. Alternative Names: 2-(Methoxy)benzothiol; 2-Mercaptoanisole; 2-Methoxybenzenethiol; 2-Methoxythiophenol; o-Methoxybenzenethiol; o-Methoxythiophenol. Grades: Highly Purified. CAS No. 7217-59-6. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |
| (3R,5S)-1-Acetyl-3,5-dimethylpiperazine | (3R,5S)-1-Acetyl-3,5-dimethylpiperazine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1-(piperazin-1-yl)butan-1-one, 18903-04-3, SureCN10514, AC1Q2UG3, CTK4D9993, 1-Butanone,1-(1-piperazinyl)-, MolPort-004-314-476, AKOS000153248, AG-E-37897, MCULE-4982582245, EN300-52092, Piperazine,1-(1-oxobutyl)- (9CI); Piperazine, 1-butyryl- (8CI); 1-(1-Oxobutyl)piperazine;1-Butyrylpiperazine; 1-n-Butyrylpiperazine. Product Category: Heterocyclic Organic Compound. CAS No. 18903-04-3. Molecular formula: C8H16N2O. Mole weight: 156.225440 [g/mol]. Purity: 0.96. IUPACName: 1-piperazin-1-ylbutan-1-one. Product ID: ACM18903043. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Butyrylcholine perchlorate | Butyrylcholine perchlorate, a potent biomedical compound, finds its application in both research and clinical environments. Serving as an acetylcholine receptor agonist, this cholinergic substance bravely delves into unraveling the intricate mechanisms governing cholinergic neurotransmission. With an unwavering dedication to scientific exploration, it illuminates the enigmatic role played by this neurotransmission in afflictions such as Alzheimer's disease, myasthenia gravis, and an array of formidable neuromuscular disorders. Synonyms: BUTYRYLCHOLINE PERCHLORATE; Trimethyl(2-(1-oxobutoxy)ethyl)ammonium perchlorate; EINECS 243-700-3; 2-butanoyloxyethyl(trimethyl)azanium; perchlorate; 566ZY7YY3K; DTXSID80174172; [2-(butanoyloxy)ethyl]trimethylazanium perchlorate; Ethanaminium, N,N,N-trimethyl-2-(1-oxobutoxy)-, perchlorate; Ethanaminium, N,N,N-trimethyl-2-(1-oxobutoxy)-, perchlorate (1:1). CAS No. 20292-68-6. Molecular formula: C9H20ClNO6. Mole weight: 273.71. |  |
| carboxylesterase | Wide specificity. The enzymes from microsomes also catalyse the reactions of EC 3.1.1.2 (arylesterase), EC 3.1.1.5 (lysophospholipase), EC 3.1.1.6 (acetylesterase), EC 3.1.1.23 (acylglycerol lipase), EC 3.1.1.28 (acylcarnitine hydrolase), EC 3.1.2.2 (palmitoyl-CoA hydrolase), EC 3.5.1.4 (amidase) and EC 3.5.1.13 (aryl-acylamidase). Also hydrolyses vitamin A esters. Group: Enzymes. Synonyms: ali-esterase; B-esterase; monobutyrase; cocaine esterase; procaine esterase; methylbutyrase; vitamin A esterase; butyryl esterase; carboxyesterase; carboxylate esterase; carboxylic esterase; methylbutyrate esterase; triacetin esterase; carboxyl ester h. Enzyme Commission Number: EC 3.1.1.1. CAS No. 9016-18-6. Esterase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3434; carboxylesterase; EC 3.1.1.1; 9016-18-6; ali-esterase; B-esterase; monobutyrase; cocaine esterase; procaine esterase; methylbutyrase; vitamin A esterase; butyryl esterase; carboxyesterase; carboxylate esterase; carboxylic esterase; methylbutyrate esterase; triacetin esterase; carboxyl ester hydrolase; butyrate esterase; methylbutyrase; α-carboxylesterase; propionyl esterase; nonspecific carboxylesterase; esterase D; esterase B; esterase A; serine esterase; carboxylic acid esterase; cocaine esterase. Cat No: EXWM-3434. |  |
| Cellulose acetate butyrate, 35-39% | Cellulose acetate butyrate (CAB) is a cellulose mixed fatty acid ester obtained from cellulose, acetic anhydride and butyric anhydride under the action of an acid catalyst. CAB is a thermoplastic resin, and the content of acetyl and butyryl groups in different products varies greatly, which has a great impact on the performance and use of the product. Cellulose acetate butyrate is an additive widely used in the coating industry. Compared with traditional cellulose acetate, it has a wider range of solubility. It not only dissolves in strong polar solvents, but also cellulose acetate butyrate with high butyryl content even Soluble in alcohol solvents. Therefore, CAB is widely used in wood coatings, plastic coatings and other coatings, and has the functions of improving coating fluidity, leveling, outdoor durability, pigment orientation and flexibility. Uses: Used in high-grade coatings, such as uv-curable coatings;photographic chemicals;polymer modification;ink. Group: Polymers. CAS No. 9004-36-8. Molecular formula: Average Mn ~12 kDa. |  |
| Cellulose acetate butyrate, 44-50% | Cellulose acetate butyrate (CAB) is a cellulose mixed fatty acid ester obtained from cellulose, acetic anhydride and butyric anhydride under the action of an acid catalyst. CAB is a thermoplastic resin, and the content of acetyl and butyryl groups in different products varies greatly, which has a great impact on the performance and use of the product. Cellulose acetate butyrate is an additive widely used in the coating industry. Compared with traditional cellulose acetate, it has a wider range of solubility. It not only dissolves in strong polar solvents, but also cellulose acetate butyrate with high butyryl content even Soluble in alcohol solvents. Therefore, CAB is widely used in wood coatings, plastic coatings and other coatings, and has the functions of improving coating fluidity, leveling, outdoor durability, pigment orientation and flexibility. Uses: Used in high-grade coatings, such as uv-curable coatings;photographic chemicals;polymer modification;ink. Group: Polymers. CAS No. 9004-36-8. Molecular formula: Average Mn ~12 kDa. | |
| Cholinesterase, Horse serum | Cholinesterase, Horse serum infers to acetylcholinesterase (AChE) and butyryl cholinesterase (BChE). AChE and BChE catalyze the hydrolysis of 6-MAM to morphine [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EC 3.1.1.8; BCHE, Horse serum. CAS No. 9001-8-5. Pack Sizes: 100 U. Product ID: HY-P2798. |  |
| Dihydrocephalomannin?e | Di hydrocephalomannin?e. Group: Biochemicals. Alternative Names: N-Debenzoyl-N- α - methyl butyrylpaclitaxel; 7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxete Benzenepropanoic Acid Derivative; [2aR-2aα,4 β,4a β,6 β, 9α(αR*, βS*), 11α, 12α, 12aα, 12bα]]-α-Hydroxy- β-[(2-methyl-1-oxobutyl)amino]-, 6, 12b-bis(acetyloxy)-12-(benzoyloxy)-2a, 3, 4, 4a, 5, 6, 9, 10, 11, 12, 12a, 12b-dodecahydro-4, 11-dihydroxy-4a, 8, 13, 13-tetramethyl-5-oxo-7, 11-methano-1H-cyclodeca[3, 4]?benz[1, 2-b]oxet-9-yl Ester Benzenepropanoic Acid; (2aR, 4S, 4aS, 6R, 9S, 11S, 12S, 12bS)-12-(Benzoyloxy)-4, 11-dihydroxy-9-(((2R, 3S)-2-hydroxy-3-(2-methylbutanamido)-3-phenylpropanoyl)oxy)-4a, 8, 13, 13-tetramethyl-5-oxo-2a, 3, 4, 4a, 5, 6, 9, 10, 11, 12, 12a, 12b-dodecahydro-1H-7, 11-methanocyclodeca[3, 4]benzo[1, 2-b]oxete-6, 12b-diyl Diacetate. Grades: Highly Purified. CAS No. 159001-25-9. Pack Sizes: 5mg. Molecular Formula: C45H55NO14, Molecular Weight: 833.92. US Biological Life Sciences. | Worldwide |
| D-Tetrahydropalmatine | D-Tetrahydropalmatine is an alkaloid isolated from a traditional Chinese herb Rhizoma Corydalis (yanhusuo). D-Tetrahydropalmatine inhibits dopamine and serotonin uptake of synaptosomes in the rat brain. D-Tetrahydropalmatine also shows inhibitory effects on acetylcholinesterase and butyrylcholinesterase. Group: Biochemicals. Alternative Names: (13aR)-5, 8, 13, 13a-Tetrahydro-2, 3, 9, 10-tetramethoxy-6H-dibenzo[a, g]quinolizine; 2,3,9,10-Tetramethoxy-13a β-berbine; (+)-(R)-Tetrahydropalmatine; (+)-2,3,9,10-Tetramethoxyberbine; (+)-Corydalis B; (R)-Tetrahydropalmatine; (+)-Tetrahydropalmatine Alkaloid; Corydalis B; d-Tetrahydropalmatine. Grades: Highly Purified. CAS No. 3520-14-7. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Floramultine | Floramultine is an isoquinoline alkaloid originally isolated from C. speciosum. It inhibits butyrylcholinesterase (BChE) and acetylcholinesterase (AChE, Kis = 23.44 and 151.3 μM, respectively). Synonyms: (S)-Floramultine; (S)-Bechuanine; Merenderine. Grades: ≥95%. CAS No. 1354-66-1. Molecular formula: C21H25NO5. Mole weight: 371.43. | |
| Garcinol | Garcinol, a polyisoprenylated benzophenone harvested from Garcinia indica , exerts anti-cholinesterase properties towards acetyl cholinesterase (AChE) and butyrylcholinesterase (BChE) with IC 50 s of 0.66 μM and 7.39 μM, respectively [1]. Garcinol also inhibits histone acetyltransferases ( HATs , IC 50 = 7 μM) and p300/CPB-associated factor ( PCAF , IC 50 = 5 μM). Garcinol has anti-inflammatory and anti-cancer activity [2]. Uses: Scientific research. Group: Natural products. CAS No. 78824-30-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-107569. | |
| Hexanedione-2,3 | Hexanedione-2,3 (Acetyl Butyryl). CAS No. 3848-24-6. FEMA No. 2558. Kosher: Y. VIGON Item # 500535. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers. | America & Internationally |
| Ladostigil | Ladostigil, also called as TV-3,326, is a novel neuroprotective agent developed to treat neurodegenerative disorders sunch as Alzheimer's disease. Ladostigil is a dual acetylcholine-butyrylcholineesterase and brain selective monoamine oxidase (MAO)-A and -B inhibitor in vivo (with little or no MAO inhibitory effect in the liver and small intestine). Synonyms: [(3R)-3-(prop-2-ynylamino)-2,3-dihydro-1H-inden-5-yl] N-ethyl-N-methylcarbamate; (N-propargyl-(3R) aminoindan-5-yl)-ethyl methyl carbamate; Ladostigil; TV 3326; TV3326; TV-3326. Grades: >98%. CAS No. 209394-27-4. Molecular formula: C16H20N2O2. Mole weight: 272.348. | |
| Ladostigil tartrate | Ladostigil, also called as TV-3,326, is a novel neuroprotective agent developed to treat neurodegenerative disorders sunch as Alzheimer's disease. Ladostigil is a dual acetylcholine-butyrylcholineesterase and brain selective monoamine oxidase (MAO)-A and -B inhibitor in vivo (with little or no MAO inhibitory effect in the liver and small intestine). Uses: A novel brain-selective mao inhibitor, ladostigil can selectively reverse the behavioral and neurochemical effects induced by prenatal stress without affecting the behavior of controls. antidepressant. Synonyms: ethylmethyl-carbamic acid (3r)-2,3-dihydro-3-(2-propynylamino)-1h-inden-5-yl ester (2r,3r)-2,3-dihydroxybutanedioate (2:1); ladostigil tartrate; Ethylmethyl-carbamic acid (3R)-2,3-dihydro-3-(2-propynylamino)-1H-inden-5-yl ester (2R,3R)-2,3-dihydroxybutaned. Grades: >98%. CAS No. 209394-46-7. Molecular formula: 2(C16H20N2O2).C4H6O6. Mole weight: 694.78. | |
| Native Equine Butyrylcholinesterase | Butyrylcholinesterase (BChE) is a serine hydrolase that is structurally similar to acetylcholinesterase (AChE), but differs in substRate specificities and inhibitor sensitivities. BChE can, unlike AChE, efficiently hydrolyze larger esters of choline such as butyrylcholine and benzoylcholine. The enzyme is a tetrameric glycoprotein with four equal subunits (110 kDa each). The enzyme is activated by Ca2+ and Mg2+ and the activity is constant over the pH range 6.0-8.0. It is inhibited by Betaine, nicotine, organophosphates, carbamates. This product is prepared from equine serum using ammonium sulfate fractionation and supplied as a lyophilized powder. Applications: Butyrylchol...vestigations into selective inhibitors may provide a clearer picture of the physiological role of bche in both healthy and diseased individuals. this product has been used for the screening of cholineesterase inhibitors in selected fruits and vegetables, for restoring cognitive function and improving memory. it has also been used to develop a butyrylcholinesterase and choline oxidase immobilized bio-sniffer for the detection of nicotine. nicotine inhibits bche activity. a decrease in the byproducts of bche activity reflects the volume of nicotine. Group: Enzymes. Synonyms: Butyrylcholinesterase; BCHE; BuChE; pseudocholinesterase; plasma cholinesterase; EC 3.1.1.8; 9001-08-5; | |
| Native Human Butyrylcholinesterase | Butyrylcholinesterase (BChE) is a serine hydrolase that is structurally similar to acetylcholinesterase (AChE), but differs in substRate specificities and inhibitor sensitivities. BChE can, unlike AChE, efficiently hydrolyze larger esters of choline such as butyrylcholine and benzoylcholine. The enzyme is a tetrameric glycoprotein with four equal subunits (110 kDa each). The enzyme is activated by Ca2+ and Mg2+ and the activity is constant over the pH range 6.0-8.0. It is inhibited by Betaine, nicotine, organophosphates, carbamates. Applications: Butyrylcholinesterase (bche) is a serine hydrolase that shares substantial structural similarities with acetylcholinesterase (ache) but has different substrate and inhibitor specificities. bche is found in the serum, hemopoietic cells, liver, lung, heart and the central nervous system of vertebrates. Group: Enzymes. Synonyms: Butyrylcholinesterase; BCHE; BuChE; pseudocholinesterase; plasma cholinesterase; EC 3.1.1.8; 9001-08-5; Acylcholine acyl-hydrolase; Choline esterase; butyryl. Enzyme Commission Number: EC 3.1.1.8. CAS No. 9001-8-5. BCHE. Activity: > 50 U/mg protein. Source: Human serum. Species: Human. Butyrylcholinesterase; BCHE; BuChE; pseudocholinesterase; plasma cholinesterase; EC 3.1.1.8; 9001-08-5; Acylcholine acyl-hydrolase; Choline esterase; butyryl. Cat No: NATE-0093. | |
| Native Human erythrocytes Acetylcholinesterase | Acetylcholinesterase, also known as AChE or acetylhydrolase, is a hydrolase that hydrolyzes the neurotransmitter acetylcholine. AChE is found at mainly neuromuscular junctions and cholinergic brain synapses, where its activity serves to terminate synaptic transmission. It belongs to carboxylesterase family of enzymes. It is the primary target of inhibition by organophosphorus compounds such as nerve agents and pesticides. The activity obtained using acetylcholine as substrate is 30-100 times that obtained with butyrylcholine, using acetylcholinesterase from electric eel. Applications: Acetylcholinesterase (ache) from creative enzymes has been used in the structure-activity study of phosphoramido acid esters as inhibitors of ache. Group: Enzymes. Synonyms: true cholinesterase; choline esterase I; cholines. Enzyme Commission Number: EC 3.1.1.7. CAS No. 9000-81-1. Acetylcholinesterase. Mole weight: ~80 kDa. Activity: > 500 units/mg protein (BCA). Storage: 2-8°C. Form: buffered aqueous solution. Solution in 20 mM HEPES, pH 8.0, containing 0.1% TRITON X-100. Source: Human erythrocytes. Species: Human. true cholinesterase; choline esterase I; cholinesterase; acetylthiocholinesterase; acetylcholine hydrolase; acetyl; β-methylcholinesterase; AcCholE; EC 3.1.1.7; 9000-81-1; Acetylcholinesterase; AChE; acetylhydrolase. Cat No: NATE-0019. | |
| Octahydroaminoacridine succinate | Octahydroaminoacridine succinate, a Tacrine analogue, is an acetylcholinesterse (AChE) and butyrylcholinesterase (BChE) inhibitor. Octahydroaminoacridine succinate can be used for Alzheimer's disease (AD) research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 866245-79-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135006. | |
| Rivastigmine | Rivastigmine (ENA 713 free base) is an orally active and potent cholinesterase (ChE) inhibitor and inhibits butyrylcholinesterase (BChE) and acetylcholinesteras (AChE) with IC 50 s of 0.037 μM , 4.15 μM, respectively. Rivastigmine can pass the blood brain barrier (BBB). Rivastigmine is a parasympathomimetic or cholinergic agent used for the research of mild to moderate dementia of the Alzheimer's type and dementia due to Parkinson's disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ENA 713 free base; SDZ-ENA 713 free base. CAS No. 123441-03-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-17368. | |
| Rivastigmine tartrate | Rivastigmine tartrate (ENA 713; SDZ-ENA 713) is an orally active and potent cholinesterase (ChE) inhibitor and inhibits butyrylcholinesterase (BChE) and acetylcholinesteras (AChE) with IC 50 s of 0.037 μM, 4.15 μM, respectively. Rivastigmine tartrate can pass the blood brain barrier (BBB). Rivastigmine tartrate is a parasympathomimetic or cholinergic agent used for the research of mild to moderate dementia of the Alzheimer's type and dementia due to Parkinson's disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ENA 713; SDZ-ENA 713. CAS No. 129101-54-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg. Product ID: HY-11017. | |
| Tacrine hydrochloride | Tacrine hydrochloride is a potent cholinesterase inhibitor used for the treatment of memory deficits in patients with Alzheimers's disease. Tacrine hydrochloride has been shown to inhibit acetylcholinesterase (AChE) and butyrylcholinesterase (IC50s = 31 and 26.5 nM, respectively). Tacrine also inhibits the uptake of serotonin and norepinephrine in rat cerebral cortex and reduces depolarization-induced calcium influx through L-type calcium channels in SN56 neuronal cells. Uses: The treatment of alzheimers's disease. Synonyms: 1,2,3,4-Tetrahydro-5-aminoacridine hydrochloride; Tacrine HCl; Hydroaminacrine; NSC72108; NSC-72108; NSC72108; Tenakrin. Grades: ≥99% by HPLC. CAS No. 1684-40-8. Molecular formula: C13H14N2.HCl. Mole weight: 234.73. | |
| Tacrine hydrochloride (hydrate) | Tacrine hydrochloride (hydrate) is an inhibitor of both acetyl ( AChE ) and butyryl-cholinestrase ( BChE ) with IC 50 s of 31 nM and 25.6 nM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 206658-92-6. Pack Sizes: 100 mg. Product ID: HY-B2244. | |
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