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| Product | Description | |
|---|---|---|
| acetylcholinesterase | Acts on a variety of acetic esters; also catalyses transacetylations. Group: Enzymes. Synonyms: true cholinesterase; choline esterase I; cholinesterase; acetylthiocholinesterase; acetylcholine hydrolase; acetyl.β-methylcholinesterase; AcCholE. Enzyme Commission Number: EC 3.1.1.7. CAS No. 9000-81-1. Acetylcholinesterase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3497; acetylcholinesterase; EC 3.1.1.7; 9000-81-1; true cholinesterase; choline esterase I; cholinesterase; acetylthiocholinesterase; acetylcholine hydrolase; acetyl.β-methylcholinesterase; AcCholE. Cat No: EXWM-3497. |  |
| Acetylcholinesterase, Electric eel | Acetylcholinesterase, Electric eel is a cholinergic enzyme that is mainly found in neuromuscular junctions and cholinergic chemical synapses and is often used in biochemical research. Acetylcholinesterase, Electric eel can catalyze the decomposition or hydrolysis of acetylcholine and some other choline esters that act as neurotransmitters into acetic acid and choline. The main function of Acetylcholinesterase, Electric eel is to terminate neuronal transmission and signal conduction between synapses to prevent ACh diffusion and activation of nearby receptors [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 9000-81-1. Pack Sizes: 500 U. Product ID: HY-P2860A. |  |
| Acetylcholinesterase Human, Recombinant | Acetylcholinesterase, also known as AChE or acetylhydrolase, is a hydrolase that hydrolyzes the neurotransmitter acetylcholine. AChE is found at mainly neuromuscular junctions and cholinergic brain synapses, where its activity serves to terminate synaptic transmission. It belongs to carboxylesterase family of enzymes. It is the primary target of inhibition by organophosphorus compounds such as nerve agents and pesticides. Group: Enzymes. Synonyms: true cholinesterase; choline esterase I; cholinesterase; acetylthiocholinesterase; acetylcholine hydrolase; acetyl; β-methylcholinesterase; AcCholE; EC 3.1.1.7; 9000-81-1; Acetylcholinesterase; AChE; acetylhydrolase. Enzyme Commission Number: EC 3.1.1.7. CAS No. 9000-81-1. Acetylcholinesterase. Activity: > 1,000 units/mg protein (Lowry). Storage: -20°C. Form: Lyophilized powder containing phosphate buffer salt. Source: HEK 293 cells. Species: Human. Cat No: NATE-0020. | |
| Native Electrophorus electricus (electric eel) Acetylcholinesterase | Acetylcholinesterase, also known as AChE or acetylhydrolase, is a hydrolase that hydrolyzes the neurotransmitter acetylcholine. AChE is found at mainly neuromuscular junctions and cholinergic brain synapses, where its activity serves to terminate synaptic transmission. It belongs to carboxylesterase family of enzymes. It is the primary target of inhibition by organophosphorus compounds such as nerve agents and pesticides. Type vi-s, lyophilized powder, 200-1000 units/mg protein; type v-s, lyophilized powder, > 1000 units/mg protein. Applications: The enzyme has been used as a reference to to evaluate the effect of aspartame metabolites on hippocampal acetylcholinesterase activity. the enzyme has also been used in immobilization studies for the rapid detection of acetylthiocholine chloride. Group: Enzymes. Synonyms: true c. Enzyme Commission Number: EC 3.1.1.7. CAS No. 9000-81-1. Acetylcholinesterase. Mole weight: 280 kDa. Activity: > 1 ,000 units/mg protein; 200-1 ,000 units/mg protein. Storage: -20°C. Form: lyophilized powder. Source: Electrophorus electricus (electric eel). true cholinesterase; choline esterase I; cholinesterase; acetylthiocholinesterase; acetylcholine hydrolase; acetyl; β-methylcholinesterase; AcCholE; EC 3.1.1.7; 9000-81-1; Acetylcholinesterase; AChE; acetylhydrolase. Cat No: NATE-0018. | |
| Native Human erythrocytes Acetylcholinesterase | Acetylcholinesterase, also known as AChE or acetylhydrolase, is a hydrolase that hydrolyzes the neurotransmitter acetylcholine. AChE is found at mainly neuromuscular junctions and cholinergic brain synapses, where its activity serves to terminate synaptic transmission. It belongs to carboxylesterase family of enzymes. It is the primary target of inhibition by organophosphorus compounds such as nerve agents and pesticides. The activity obtained using acetylcholine as substrate is 30-100 times that obtained with butyrylcholine, using acetylcholinesterase from electric eel. Applications: Acetylcholinesterase (ache) from creative enzymes has been used in the structure-activity study of phosphoramido acid esters as inhibitors of ache. Group: Enzymes. Synonyms: true cholinesterase; choline esterase I; cholines. Enzyme Commission Number: EC 3.1.1.7. CAS No. 9000-81-1. Acetylcholinesterase. Mole weight: ~80 kDa. Activity: > 500 units/mg protein (BCA). Storage: 2-8°C. Form: buffered aqueous solution. Solution in 20 mM HEPES, pH 8.0, containing 0.1% TRITON X-100. Source: Human erythrocytes. Species: Human. true cholinesterase; choline esterase I; cholinesterase; acetylthiocholinesterase; acetylcholine hydrolase; acetyl; β-methylcholinesterase; AcCholE; EC 3.1.1.7; 9000-81-1; Acetylcholinesterase; AChE; acetylhydrolase. Cat No: NATE-0019. | |
| 1,1-Dibenzyl-4-[(5,6-dimethoxy-1-oxo-2,3-dihydro-1H-inden-2-yl)methyl]-1-piperidinium Bromide | Donepezil impurity. Uses: 4-[(2,3-dihydro-5,6-dimethoxy-1-oxo-1h-inden-2-yl)methyl]-1,1-bis(phenylmethyl)piperidinium is an isotope labelled impurity in the synthesis of donepezil (d531750), an inhibitor of acetylcholinesterase. Synonyms: 2-[[1,1-bis(phenylmethyl)-4-piperidin-1-iumyl]methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one;bromide; 2-[(1,1-dibenzylpiperidin-1-ium-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one;bromide. Grades: > 95 %. CAS No. 844694-85-5. Molecular formula: C31H36BrNO3. Mole weight: 550.53. |  |
| 1,2-Di-[(Trishydroxymethyl)aminomethane]-succinamide | 1,2-Di-[(Trishydroxymethyl)aminomethane]-succinamide, a compound widely utilized in the biomedicine industry, demonstrates immense potentialities in the treatment of several neurological disorders and afflictions concerning the nervous system. Its ability to act as an acetylcholinesterase inhibitor renders it a promising candidate for treating diseases such as Alzheimer's disease, multiple sclerosis, and neuropathic pain. By enhancing the function of the nervous system, this product exhibits remarkable therapeutic efficacy. | |
| 1,3,9-Trimethyluric Acid | 1,3,9-Trimethyluric Acid has been found in rat urine as a metabolite of Caffeine (C080100), a bitter, white crystalline xanthine alkaloid that acts as a stimulant drug and a reversible acetylcholinesterase inhibitor. Caffeine is found in varying quantities in the seeds, leaves, and fruit of some plants, where it acts as a natural pesticide that paralyzes and kills certain insects feeding on the plants. Group: Biochemicals. Grades: Highly Purified. CAS No. 7464-93-9. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C8H10N4O3, Molecular Weight: 210.19. US Biological Life Sciences. |  Worldwide |
| 1- (4-Methylbenzyl) piperazine | 1- (4-Methylbenzyl) piperazine is a useful synthetic intermediate in the synthesis of 3-Desmethyl 4-Methyl Meclizine Dihydrochloride (D291930); a metabolite of Meclizine (M202700, 2HCl monohydrate) which is an antiemetic. 1- (4-Methylbenzyl) piperazine is also used in the synthesis of inhibitors of acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE). Group: Biochemicals. Grades: Highly Purified. CAS No. 23173-57-1. Pack Sizes: 1g, 5g. Molecular Formula: C12H18N2, Molecular Weight: 190.28. US Biological Life Sciences. | Worldwide |
| 1, 5-Bis (4-Allyldimethyl Ammonium phenyl) pentan-3-one, Dibromide | A selective acetylcholinesterase inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| 1,5-Diepi-adenophorine | 1,5-Diepi-adenophorine is a natural compound that boasts remarkable anti-inflammatory, antioxidant, and neuroprotective properties. A key molecule in the fight against neurological disorders, it has earned its stripes in treating Alzheimer's and Parkinson's diseases through its ability to inhibit the activity of acetylcholinesterase. Yet its antitumor capabilities cannot be overlooked as 1,5-Diepi-adenophorine has displayed a unique ability to induce cell cycle arrest and apoptosis in various cancer cell lines. The evidence is clear - 1,5-Diepi-adenophorine is a multifaceted agent for high-value therapeutics and treatments. | |
| 1,7,9-Trimethyluric Acid | 1,7,9-Trimethyluric Acid is an intermediate in the synthesis of Methylliberine (M315730), an alkaloid metabolite of Caffeine (C080100), a bitter, white crystalline xanthine alkaloid that acts as a stimulant drug and a reversible acetylcholinesterase inhibitor. Caffeine is found in varying quantities in the seeds, leaves, and fruit of some plants, where it acts as a natural pesticide that paralyzes and kills certain insects feeding on the plants. Group: Biochemicals. Grades: Highly Purified. CAS No. 55441-64-0. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C8H10N4O3, Molecular Weight: 210.19. US Biological Life Sciences. | Worldwide |
| 1,9-Dimethyluric Acid | 1,9-Dimethyluric Acid is an intermediate in the synthesis of Liberine (L397680), an alkaloid metabolite of Caffeine (C080100), a bitter, white crystalline xanthine alkaloid that acts as a stimulant drug and a reversible acetylcholinesterase inhibitor. Caffeine is found in varying quantities in the seeds, leaves, and fruit of some plants, where it acts as a natural pesticide that paralyzes and kills certain insects feeding on the plants. Group: Biochemicals. Grades: Highly Purified. CAS No. 55441-62-8. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C7H8N4O3, Molecular Weight: 196.16. US Biological Life Sciences. | Worldwide |
| 1-Benzyl-4-[(5,6-dimethoxy-1-oxoindan-2-yl)methyl]-1,2,3,6-tetrahydropyridine | 1-Benzyl-4-[(5,6-dimethoxy-1-oxoindan-2-yl)methyl]-1,2,3,6-tetrahydropyridine is one of Donepezil impurities. Donepezil, a highly specific reversible acetylcholinesterase (AChE) inhibitor, is used to treat moderate to severe Alzheimer's disease. Synonyms: 2,3-Dihydro-5,6-dimethoxy-2-[[1,2,3,6-tetrahydro-1-(phenylmethyl)-4-pyridinyl]methyl]-1H-inden-1-one; Donepezil Impurity 28; Donepezil Impurity G. Grades: > 98%. CAS No. 608511-44-0. Molecular formula: C24H27NO3. Mole weight: 377.48. | |
| 1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-yl)methylene-1,2,3,4-tetrahydropyridine | 1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-yl)methylene-1,2,3,4-tetrahydropyridine is one of Donepezil impurities. Donepezil, a highly specific reversible acetylcholinesterase (AChE) inhibitor, is used to treat moderate to severe Alzheimer's disease. Uses: Donepezil. Synonyms: 2,3-Dihydro-5,6-dimethoxy-2-[[1,2,3,4-tetrahydro-1-(phenylmethyl)-4-pyridinyl]methylene]-1H-inden-1-one; 2-((1-benzyl-2,3-dihydropyridin-4(1H)-ylidene)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one. Grades: > 98%. CAS No. 1020661-51-1. Molecular formula: C24H25NO3. Mole weight: 375.46. | |
| 1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-yl)methylpyridinium Bromide | 1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-yl)methylpyridinium Bromide is one of Donepezil impurities. Donepezil, a highly specific reversible acetylcholinesterase (AChE) inhibitor, is used to treat moderate to severe Alzheimer's disease. Uses: Donepezil. Synonyms: 4-[(2,3-Dihydro-5,6-dimethoxy-1-oxo-1H-inden-2-yl)methyl]-1-(phenylmethyl)pyridinimBromide; Donepezil Impurity 5; 1-benzyl-4-((5,6-dimethoxy-1-oxo-2,3-dihydro-1H-inden-2-yl)methyl)pyridin-1-ium,bromide (1:1). CAS No. 231283-82-2. Molecular formula: C24H24BrNO3. Mole weight: 454.36. | |
| 1-Benzyl-4- [ (5-benzyloxy-6-methoxy-1-indanone) -2-ylidenyl] methylpiperidine | A benzylalkylpiperidine derivative as acetylcholinesterase inhibitor. Group: Biochemicals. Alternative Names: 2,3-Dihydro-6-methoxy-5-(phenylmethoxy)-2-[[1-(phenylmethyl)-4-piperidinyl]methylene]-1H-inden-1-one. Grades: Highly Purified. CAS No. 120013-75-4. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 1-Benzyl-4- [ (6-benzyloxy-5-methoxy-1-indanone) -2-ylidenyl] methylpiperidine | A benzylalkylpiperidine derivative as acetylcholinesterase inhibitor. Group: Biochemicals. Alternative Names: 2,3-Dihydro-5-methoxy-6-(phenylmethoxy)-2-[[1-(phenylmethyl)-4-piperidinyl]methylene]-1H-inden-1-one. Grades: Highly Purified. CAS No. 1076198-90-7. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| 1- (Benzyl-d5) -4- [ (5-benzyloxy-6-methoxy-1-indanone) -2-ylidenyl] methylpiperidine | A labeled benzylalkylpiperidine derivative as acetylcholinesterase inhibitor. Group: Biochemicals. Alternative Names: 2,3-Dihydro-6-methoxy-5-(phenylmethoxy)-2-[[1-(phenylmethyl)-4-piperidinyl]methylene]-1H-inden-1-one. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 1- (Benzyl-d5) -4- [ (6-benzyloxy-5-methoxy-1-indanone) -2-ylidenyl] methylpiperidine | A labeled benzylalkylpiperidine derivative as acetylcholinesterase inhibitor. Group: Biochemicals. Alternative Names: 2,3-Dihydro-5-methoxy-6-(phenylmethoxy)-2-[[1-(phenyl-d5-methyl)-4-piperidinyl]methylene]-1H-inden-1-one. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 1-Deoxo-1,2-dehydro-N-desbenzyl-N-tert-butyloxycarbonyl Donepezil | 1-Deoxo-1,2-dehydro-N-desbenzyl-N-tert-butyloxycarbonyl Donepezil is one of Donepezil derivatives. Donepezil, a highly specific reversible acetylcholinesterase (AChE) inhibitor, is used to treat moderate to severe Alzheimer's disease. Synonyms: 2-Methyl-2-propanyl 4-[(5,6-dimethoxy-1H-inden-2-yl)methyl]-1-piperidinecarboxylate; 1-Piperidinecarboxylic acid, 4-[(5,6-dimethoxy-1H-inden-2-yl)methyl]-, 1,1-dimethylethyl ester. Grades: ≥95%. CAS No. 1346600-41-6. Molecular formula: C22H31NO4. Mole weight: 373.48. | |
| 1-Hexacosanol | 1-Hexacosanol is a compound in the bioactive fraction of plant extracts that mediates insecticidal activity. 1-Hexacosanol has larvicidal activity and can inhibit the acetylcholinesterase activity of Culex quinquefasciatus , Aedes aegypti and Chironomus riparius , exerting neurotoxic effects [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Ceryl Alcohol. CAS No. 506-52-5. Pack Sizes: 10 mg. Product ID: HY-W127493. | |
| 1-Methylpyridin-1-ium-2-carboxamide | 1-Methylpyridin-1-ium-2-carboxamide is an impurity of Pralidoxime Chloride, a drug that binds to organophosphate-inactivated acetylcholinesterase and is used for the treatment of organophosphate poisoning. Synonyms: 1-Methyl-2-carbamoylpyridinium; 1-methylpyridine-2-carboxamide; 2-Carbamoyl-1-methyl-pyridinium. CAS No. 45750-74-1. Molecular formula: C7H9ClN2O. Mole weight: 172.61. | |
| 1-methylpyridin-1-ium-2-carboxamide chloride | An impurity of Pralidoxime Chloride. Pralidoxime Chloride is a drug that binds to organophosphate-inactivated acetylcholinesterase and is used for the treatment of organophosphate poisoning. Synonyms: 21032-31-5; 2-Carbamoyl-1-methylpyridin-1-ium chloridePyridinium, 2-(aminocarbonyl)-1-methyl-, chloride (1:1); SCHEMBL8434012; DTXSID70545796. Grades: 95%. CAS No. 21032-31-5. Molecular formula: C7H9ClN2O. Mole weight: 172.61. | |
| 1-methylpyridin-1-ium-2-carboxamide iodide | An impurity of Pralidoxime Chloride. Pralidoxime Chloride is a drug that binds to organophosphate-inactivated acetylcholinesterase and is used for the treatment of organophosphate poisoning. Synonyms: 2-Carbamoyl-1-methylpyridinium iodide; 3861-69-6; 2-(AMINOCARBONYL)-1-METHYLPYRIDINIUM IODIDE; PCMM; 2-CARBAMOYL-1-METHYLPYRIDIN-1-IUM IODIDE; Iodide 2-(aminocarbonyl)-1-methylpyridinium; Pyridinium, 2-(aminocarbonyl)-1-methyl-, iodide; Pyridinium, 2-carbamoyl-1-methyl-, iodide; 1-methylpyridin-1-ium-2-carboxamide; iodide. Grades: 95%. CAS No. 3861-69-6. Molecular formula: C7H9IN2O. Mole weight: 264.06. | |
| 1-methylpyridin-1-ium-2-carboxylic acid | 1-methylpyridin-1-ium-2-carboxylic acid is an impurity of Pralidoxime Chloride, a drug that binds to organophosphate-inactivated acetylcholinesterase and is used for the treatment of organophosphate poisoning. Synonyms: Homarine Hydrochloride. CAS No. 3697-38-9. Molecular formula: C7H8ClNO2. Mole weight: 173.596. | |
| 1-Methyl-pyridinium Chloride | 1-Methyl-pyridinium Chloride is a degradation product of pralidoxime chloride (P701120) in concentrated acidic solution. pralidoxime chloride (P701120) binds to inactivated acetylcholinesterases and is used to combat poisoning from organophosphates and nerve agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 7680-73-1. Pack Sizes: 1g, 5g. Molecular Formula: C6H8ClN. US Biological Life Sciences. | Worldwide |
| 1-Naphthyl acetate | 1-Naphthyl acetate is an attractive chromogenic substrate for the detection of erythrocyte acetylcholinesterase ( AChE ) activity. 1-Naphthyl acetate has the potential to detect organophosphorus pesticide (OP) poisoning [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 830-81-9. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-W016188. | |
| 2-((1-Benzyl-3-hydroxypiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one | 2-((1-Benzyl-3-hydroxypiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one is one of Donepezil analogues. Donepezil, a highly specific reversible acetylcholinesterase (AChE) inhibitor, is used to treat moderate to severe Alzheimer's disease. Synonyms: 2-[(1-Benzyl-3-hydroxy-4-piperidinyl)methyl]-5,6-dimethoxy-1-indanone; 1H-Inden-1-one, 2,3-dihydro-2-[[3-hydroxy-1-(phenylmethyl)-4-piperidinyl]methyl]-5,6-dimethoxy-. Molecular formula: C24H29NO4. Mole weight: 395.49. | |
| 2,2,2-Trifluoroacetophenone | 2,2,2-Trifluoroacetophenone is a fluorinated acetophenone with inhibitory activity of acetylcholinesterase. 2,2,2-Trifluoroacetophenone was shown to have neuroprotective activity by inhibiting apoptosis in cerebellar granule neurons. Group: Biochemicals. Alternative Names: (Trifluoroacetyl) benzene; 2,2,2-Trifluoro-1-phenyl-1-ethanone; 2,2,2-Trifluoro-1-phenylethanone; NSC 42752; Phenyl Trifluoromethyl Ketone; Trifluoromethyl Phenyl Ketone; α, α, α-Trifluoroacetophenone; ω, ω, ω-Trifluoroacetophenone. Grades: Highly Purified. CAS No. 434-45-7. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| 2-(3-(1-Benzylpiperidin-4-yl)-2-oxopropyl)-4,5-dimethoxybenzoic Acid Benzyl Ester | 2-(3-(1-Benzylpiperidin-4-yl)-2-oxopropyl)-4,5-dimethoxybenzoic Acid Benzyl Ester is an impurity of Donepezil (D531750), an inhibitor of acetylcholinesterase. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 5mg. Molecular Formula: C31H35NO5. US Biological Life Sciences. | Worldwide |
| 2-(3-(1-Benzylpiperidin-4-yl)-2-oxopropyl)-4,5-dimethoxybenzoic Acid Benzyl Ester | 2-(3-(1-Benzylpiperidin-4-yl)-2-oxopropyl)-4,5-dimethoxybenzoic Acid Benzyl Ester is one of Donepezil impurities. Donepezil, a highly specific reversible acetylcholinesterase (AChE) inhibitor, is used to treat moderate to severe Alzheimer's disease. Molecular formula: C31H35NO5. Mole weight: 501.61. | |
| 2,3-Dihydro-2-hydroxy-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-inden-1-one | 2,3-Dihydro-2-hydroxy-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-inden-1-one is one of Donepezil analogues. Donepezil, a highly specific reversible acetylcholinesterase (AChE) inhibitor, is used to treat moderate to severe Alzheimer's disease. Synonyms: 1-benzyl-4-[(5,6-dimethoxy-2-hydroxy-1-indanon)-2-yl]methylpiperidine; 2-[(1-benzylpiperidin-4-yl)methyl]-2-hydroxy-5,6-dimethoxy-3H-inden-1-one; 2-Hydroxy-2-[(1-benzyl-4-piperidinyl)methyl]-5,6-dimethoxyindan-1-one; 1H-Inden-1-one, 2,3-dihydro-2-hydroxy-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-. Grades: ≥95%. CAS No. 329010-67-5. Molecular formula: C24H29NO4. Mole weight: 395.49. | |
| 2,3-Dihydro-5,6-dimethoxy-2-[(1-oxido-4-pyridinyl)methylene]-1H-inden-1-one | 2,3-Dihydro-5,6-dimethoxy-2-[(1-oxido-4-pyridinyl)methylene]-1H-inden-1-one is an impurity of donepezil (D531750) which is a nootropic and an inhibitor of acetylcholinesterase. Group: Biochemicals. Grades: Highly Purified. CAS No. 896134-06-8. Pack Sizes: 10mg, 50mg. Molecular Formula: C17H15NO4. US Biological Life Sciences. | Worldwide |
| (2E)-2-(2,3-Dihydro-5,6-dimethoxy-1H-inden-1-ylidene)-2,3-dihydro-5,6-dimethoxy-1H-inden-1-one | (2E)-2-(2,3-Dihydro-5,6-dimethoxy-1H-inden-1-ylidene)-2,3-dihydro-5,6-dimethoxy-1H-inden-1-one is one of Donepezil impurities. Donepezil, a highly specific reversible acetylcholinesterase (AChE) inhibitor, is used to treat moderate to severe Alzheimer's disease. Synonyms: 879973-83-8; 2-(5,6-Dimethoxyindan-1-ylidene)-5,6-dimethoxyindan-1-one(2E)-2-(2,3-Dihydro-5,6-dimethoxy-1H-inden-1-ylidene)-2,3-dihydro-5,6-dimethoxy-1H-inden-1-one. Grades: 98%. CAS No. 879973-83-8. Molecular formula: C22H22O5. Mole weight: 366.41. | |
| (2E)-Dehydrodonepezil. (Donepezil Impurity) | (2E)-Dehydrodonepezil (Donepezil USP Related Compound A) is a derivative of Donepezil (D531750), a nootropic. An inhibitor of acetylcholinesterase. Group: Biochemicals. Grades: Highly Purified. CAS No. 145546-80-1. Pack Sizes: 1mg, 5mg. Molecular Formula: C24H27NO3. US Biological Life Sciences. | Worldwide |
| 2-Ethoxybenzo[b]thiophen-4-ol | 2-Ethoxybenzo[b]thiophen-4-ol is an impurity of Donepezil (D525745), which is an inhibitor of acetylcholinesterase; nootropic drug. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C10H10O2S, Molecular Weight: 194.25. US Biological Life Sciences. | Worldwide |
| 2-Ethoxybenzo[b]thiophen-4-ol | 2-Ethoxybenzo[b]thiophen-4-ol is one of Donepezil impurities. Donepezil, a highly specific reversible acetylcholinesterase (AChE) inhibitor, is used to treat moderate to severe Alzheimer's disease. Synonyms: Donepezil Impurity 12. Molecular formula: C10H10O2S. Mole weight: 194.25. | |
| 2-Fluorotoluene-α-d1 | 2-Fluorotoluene-α-d1 is labelled 2-Fluorotoluene which was used in the study of E2020 as a potent acetylcholinesterase (AChE) inhibitor. It was also used to study substituted indanone and benzylpiperidine ring substructures of a set of AChE inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 17359-78-3. Pack Sizes: 50mg, 250mg. Molecular Formula: C7H6DF, Molecular Weight: 111.14. US Biological Life Sciences. | Worldwide |
| 2-(Hydroxy(pyridin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one | 2-(Hydroxy(pyridin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one is one of Donepezil impurities. Donepezil, a highly specific reversible acetylcholinesterase (AChE) inhibitor, is used to treat moderate to severe Alzheimer's disease. CAS No. 2227606-37-1. Molecular formula: C17H17NO4. Mole weight: 299.32. | |
| 2-Methoxythiophenol | 2-Methoxythiophenol is used in the synthesis of berberine-thiophenyl hybrids as multifunctional agents. Inhibition of acetylcholinesterase, butyrylcholinesterase and AB aggregation antioxidant activity. Group: Biochemicals. Alternative Names: 2-(Methoxy)benzothiol; 2-Mercaptoanisole; 2-Methoxybenzenethiol; 2-Methoxythiophenol; o-Methoxybenzenethiol; o-Methoxythiophenol. Grades: Highly Purified. CAS No. 7217-59-6. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |
| 2-(Piperidinylmethyl) Hydroxy Donepezil | 2-(Piperidinylmethyl) Hydroxy Donepezil is one of Donepezil impurities. Donepezil, a highly specific reversible acetylcholinesterase (AChE) inhibitor, is used to treat moderate to severe Alzheimer's disease. Synonyms: 2,3-Dihydro-2-[hydroxyl-1-phenylmethyl)-4-piperidinyl]methyl]-5,6-dimethoxy-2-(piperidinylmethyl)-1H-inden-1-one. Grades: 98%. CAS No. 1391052-12-2. Molecular formula: C30H40N2O4. Mole weight: 492.65. | |
| (3α)-3-Deoxy-3-chlorogalanthamine | Galanthamine (G188500) derivative, a cortical acetylcholinesterase (AChE) inhibitor. Group: Biochemicals. Alternative Names: (4aS,6S,8aS)-6-Chloro-4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepine. Grades: Highly Purified. CAS No. 146274-40-0. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| 3-Carene | 3-Carene is a mutagenic compound that may be found in the fumes of heating freshly cut spruce and birch chips. 3-Carene is also found i many esential oils and it inhibits acetylcholinesterase activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 13466-78-9. Pack Sizes: 100g, 250g. Molecular Formula: C10H16. US Biological Life Sciences. | Worldwide |
| 3-Carene-D3 | Deuterium labelled isotope of 3-Carene, which is a mutagenic compound that may be found in the fumes of heating freshly cut spruce and birch chips. 3-Carene is also found i many esential oils and it inhibits acetylcholinesterase activity. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C10H13D3, Molecular Weight: 139.25. US Biological Life Sciences. | Worldwide |
| 3-Hydroxy carbofuran | 3-Hydroxy carbofuran is an active metabolite of carbofuran, which is an insecticide that inhibits acetylcholinesterase in mammals and insects. Synonyms: Carbofuran-3-hydroxy. Grades: ≥98%. CAS No. 16655-82-6. Molecular formula: C12H15NO4. Mole weight: 237.2. | |
| 3-Hydroxy Donepezil | 3-Hydroxy Donepezil is one of Donepezil impurities. Donepezil, a highly specific reversible acetylcholinesterase (AChE) inhibitor, is used to treat moderate to severe Alzheimer's disease. Synonyms: 2-((1-Benzylpiperidin-4-yl)methyl)-3-hydroxy-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one. Grades: > 90%. CAS No. 2097683-67-3. Molecular formula: C24H29NO4. Mole weight: 395.50. | |
| 4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-[1,1'-Biphenyl]-2-carbonitrile | A butyl diazaspirononenone derivative used in the preparation of acetylcholinesterase inhibitors. An impurity found in Irbesartan. Group: Biochemicals. Alternative Names: 2-Butyl-3-[[2'-(cyano)biphenyl-4-yl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one. Grades: Highly Purified. CAS No. 138401-24-8. Pack Sizes: 2.5g. US Biological Life Sciences. | Worldwide |
| 4-Pyridinealdoxime | An intermediate for bis (hydroxyimino methyl pyridinium) butenes as reactivators of chlorpyrifos-inhibited acetylcholinesterase. Group: Biochemicals. Alternative Names: Isonicotinaldehyde Oxime. Grades: Highly Purified. CAS No. 696-54-8. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| 5,5'-Dithiobis(2-nitrobenzoic acid) | 3,3'-Dithiobis[6-nitrobenzoic Acid is an membrane-impermeant thiol/disulfide exchange blocker. Also used to quantify the number or concentration of thiol groups in a sample. Ellman?s reagent maybe used for acetylcholinesterase assay, and to specifically label cysteine residues. It is a sensitive reagent for measuring the free sulfhydryl content in proteins, peptides, and tissues. Group: Biochemicals. Alternative Names: 2,2'-Dinitro-5,5'-dithiodibenzoic Acid; 3,3'-Dithiobis(6-nitrobenzoic Acid); 5,5'-Dithiobis[2-nitrobenzoic Acid]; Ba 2767; DTNB; Ellmans Reagent. Grades: Highly Purified. CAS No. 69-78-3. Pack Sizes: 25g, 50g, 100g. Molecular Formula: C??H?N?O?S?. US Biological Life Sciences. | Worldwide |
| 5,6-Dimethoxy-2-(4-piperidinyl)methyleneindan-1-one | 5,6-Dimethoxy-2-(4-piperidinyl)methyleneindan-1-one is one of Donepezil impurities. Donepezil, a highly specific reversible acetylcholinesterase (AChE) inhibitor, is used to treat moderate to severe Alzheimer's disease. Uses: An impurity of donepezil. Synonyms: 2,3-Dihydro-5,6-dimethoxy-2-(4-piperidinylmethylene)-1H-inden-1-one; DPMI. Grades: > 98%. CAS No. 149874-91-9. Molecular formula: C17H21NO3. Mole weight: 287.35. | |
| 5,6-Dimethoxy-2-(4-pyridylmethyl)-1-indanone | 5,6-Dimethoxy-2-(4-pyridylmethyl)-1-indanone is one of Donepezil impurities. Donepezil, a highly specific reversible acetylcholinesterase (AChE) inhibitor, is used to treat moderate to severe Alzheimer's disease. Uses: Donepezil (d531750) impurity. Synonyms: Donepezil impurity; (+/-)-5,6-Dimethoxy-2-(pyridin-4-ylmethyl)indan-1-one; 2,3-dihydro-5,6-dimethoxy-2-((pyridin-4-yl)methyl)inden-1-one. Grades: > 95 %. CAS No. 4803-57-0. Molecular formula: C17H17NO3. Mole weight: 283.32. | |
| 5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone | 5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone is one of Donepezil impurities. Donepezil, a highly specific reversible acetylcholinesterase (AChE) inhibitor, is used to treat moderate to severe Alzheimer's disease. Uses: An impurity of donepezil. Synonyms: 2,3-Dihydro-5,6-dimethoxy-2-(4-pyridinylmethylene)-1H-inden-1-one; Donepezil Impurity; 5,6-Dimethoxy-2-(pyridine-4-yl)methylene-indan-1-one; 5,6-Dimethoxy-2-(pyridin-4-ylmethylene)-2,3-dihydro-1H-inden-1-one; (E)-5,6-dimethoxy-2-(pyridin-4-ylmethylene)-2,3-dihydroinden-1-one; Donepezil Pyridine Dehydro Impurity. Grades: > 98 %. CAS No. 4803-74-1. Molecular formula: C17H15NO3. Mole weight: 281.31. | |
| 5-Desmethoxy-7-methoxy Donepezil Hydrochloride | 5-Desmethoxy-7-methoxy Donepezil Hydrochloride is a derivative of Donepezil, which is a highly specific reversible acetylcholinesterase (AChE) inhibitor used to treat moderate to severe Alzheimer's disease. Synonyms: 2-((1-Benzylpiperidin-4-yl)methyl)-6,7-dimethoxy-2,3-dihydro-1H-inden-1-one hydrochloride; 2,3-Dihydro-6,7-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-inden-1-one Hydrochloride; 2-[(1-Benzyl-4-piperidinyl)methyl]-6,7-dimethoxy-1-indanone hydrochloride (1:1); 1H-Inden-1-one, 2,3-dihydro-6,7-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-, hydrochloride (1:1). Grades: 98%. CAS No. 120013-51-6. Molecular formula: C24H29NO3.HCl. Mole weight: 415.95. | |
| 5-O-Desmethyl Donepezil (1-Benzyl-4-[(5-hydroxy-6-methoxy-1-oxo-indan-2-yl)methylpiperidine) | A metabolite of Donepezil, an inhibitor of acetylcholinesterase. Group: Biochemicals. Alternative Names: 1-Benzyl-4-[(5-hydroxy-6-methoxy-1-oxo-indan-2-yl)methylpiperidine. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| 6-O-Desmethyl Donepezil (1-Benzyl-4-[(6-hydroxy-5-methoxy-1-oxo-indan-2-yl)methylpiperidine) | A metabolite of Donepezil, an inhibitor of acetylcholinesterase. Group: Biochemicals. Alternative Names: 1-Benzyl-4-[(6-hydroxy-5-methoxy-1-oxo-indan-2-yl)methylpiperidine. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| 6-O-Desmethyl Donepezil-d5 (1-(Benzyl-d5)-4-[(6-hydroxy-5-methoxy-1-oxo-indan-2-yl)methylpiperidine) | A labeled metabolite of Donepezil, an inhibitor of acetylcholinesterase. Group: Biochemicals. Alternative Names: 1-(Benzyl-d5)-4-[(6-hydroxy-5-methoxy-1-oxo-indan-2-yl)methylpiperidine. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| 6-O-Desmethyl Donepezil Glucuronide Sodium Salt (Mixture of Diastereomers) | 6-O-Desmethyl Donepezil Glucuronide Sodium Salt (Mixture of Diastereomers) is one of Donepezil impurities. Donepezil, a highly specific reversible acetylcholinesterase (AChE) inhibitor, is used to treat moderate to severe Alzheimer's disease. Synonyms: (2S,3S,4S,5R,6S)-6-((2-((1-benzylpiperidin-4-yl)methyl)-6-methoxy-3-oxo-2,3-dihydro-1H-inden-5-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid, sodium salt (1:1). Molecular formula: C29H34NO9.Na. Mole weight: 563.57. | |
| Acetyllovastatin | Acetyllovastatin, a acetate of Lovastatin, presentes a moderate inhibitory effect against the enzyme acetylcholinesterase with an IC 50 of 79 μg/mL. Lovastatin has been found to display antifungal activity, and suppresses proliferation of a number of transformed cell lines [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 81189-92-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-126237. | |
| acetylsalicylate deacetylase | Not identical with EC 3.1.1.1 (carboxylesterase), EC 3.1.1.2 (arylesterase), EC 3.1.1.7 (acetylcholinesterase) or EC 3.1.1.8 (cholinesterase). The activity of the liver cytosol enzyme is highest with acetyl esters of aryl alcohols, and thioesters are also hydrolysed; the microsomal enzyme also hydrolyses some other negatively charged esters, with highest activity on esters of salicylate with long-chain alcohols. Group: Enzymes. Synonyms: aspirin esterase; aspirin esterase; acetylsalicylic acid esterase; aspirin hydrolase. Enzyme Commission Number: EC 3.1.1.55. CAS No. 87348-04-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3483; acetylsalicylate deacetylase; EC 3.1.1.55; 87348-04-7; aspirin esterase; aspirin esterase; acetylsalicylic acid esterase; aspirin hydrolase. Cat No: EXWM-3483. | |
| a-Chaconine | a-Chaconine is a genotoxic agent that inhibits the production of energy through mitochondrial electron transport and ATP synthesis. It binds to the matrix effect, which is a protective barrier against the passage of toxic substances from blood to other organs. This compound also has anti-inflammatory effects and is used in vitro assays for assessing the effects of chemical compounds on cell growth. a-Chaconine has been shown to inhibit acetylcholinesterase activity in rats, leading to acute toxicities such as respiratory depression. This compound also causes DNA strand breaks in vitro, and can be detected using polymerase chain reaction (PCR) analysis. Group: Other alkaloids. Alternative Names: (3b)-Solanid-5-en-3-yl O-6-deoxy-a-L-mannopyranosyl-(1-2)-O-(6-deoxy-a-L-mannopyranosyl-(1-4))-b-D-glucopyranoside. CAS No. 20562-03-2. Molecular formula: C45H73NO14. Mole weight: 852.06 g/mol. Canonical SMILES: C[C@H]1CC[C@@H]2[C@H] ([C@H]3[C@@H] (N2C1)C[C@@H]4[C@@]3 (CC[C@H]5[C@H]4CC=C6[C@@]5 (CC[C@@H] (C6)O[C@H]7[C@@H] ([C@H] ([C@@H] ([C@H] (O7)CO)O[C@H]8[C@@H] ([C@@H] ([C@H] ([C@@H] (O8)C)O)O)O)O)O[C@H]9[C@@H] ([C@@H] ([C@H] ([C@@H] (O9)C)O)O)O)C)C)C. Catalog: ACM20562032. |  |
| Acotiamide | Acotiamide is an orally active, selective and reversible acetylcholinesterase ( AChE ) inhibitor, with an IC 50 of 1.79 μM. Acotiamide can enhance gastric contractility and accelerate delayed gastric emptying. Acotiamide has the potential for the research of functional dyspepsia involving gastric motility dysfunction and intestinal inflammatory [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Z-338 free base; YM443 free base. CAS No. 185106-16-5. Pack Sizes: 25 mg; 50 mg. Product ID: HY-121467. | |
| Acotiamide | Acotiamide is a potent and seletive inhibitor of human and canine stomach-derived acetylcholinesterase (AChE). Acotiamide has been approved in Japan for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia. Uses: Cholinesterase inhibitors. Synonyms: Acotiamide;MZ-338;UNII-D42OWK5383. CAS No. 185106-16-5. Molecular formula: C21H30N4O5S. Mole weight: 450.554. | |
| Acotiamide-[d6] | Labelled Acotiamide. Acotiamide is a potent and selective inhibitor of human and canine stomach-derived acetylcholinesterase (AChE). Acotiamide has been approved in Japan for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia. Synonyms: N-{2-[bis(propan-2-yl)amino]ethyl}-2-[2-hydroxy-4,5-bis(D3)methoxybenzamido]-1,3-thiazole-4-carboxamide. Molecular formula: C21H24D6N4O5S. Mole weight: 456.59. | |
| Acotiamide Hydrochloride | Acotiamide Hydrochloride is an acetylcholinesterase inhibitor which has been shown to stimulate gastric motility and improve gastric motility dysfunction in rats (1,2). Acotiamide Hydrochloride has also been shown to improve meal-related symptoms of functional dyspepsia. Group: Biochemicals. Grades: Highly Purified. CAS No. 185104-11-4. Pack Sizes: 5mg, 50mg. Molecular Formula: C21H31ClN4O5S, Molecular Weight: 487.01. US Biological Life Sciences. | Worldwide |
| Acotiamide Methyl Ether-d9 | Acotiamide Methyl Ether-d9 is the isotope labelled analog of Acotiamide Methyl Ether (A190265); a metabolite of Acotiamide (A190260, HCl) which is an acetylcholinesterase inhibitor which has been shown to stimulate gastric motility and improve gastric motility dysfunction in rats. Acotiamide Hydrochloride has also been shown to improve meal-related symptoms of functional dyspepsia. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C22H23D9N4O5S, Molecular Weight: 473.63. US Biological Life Sciences. | Worldwide |
| Altenusin | Altenusin is a a biphenyl derivative with an IC50 value of 4.3±0.3 μM in the TR assay, which is isolated from the endophytic fungus Alternaria. It inhibits Src kinase with an IC50 value of 20 nM. Altenusin inhibits fibrillization of recombinant tau fragments in vitro and phosphorylation of tau in SH-SY5Y cells expressing human P301L mutant tau when used at a concentration of 10 μM. Altenusin is known to have antioxidant properties and to inhibit several enzymes, including myosin light chain kinase, sphingomyelinase, acetylcholinesterase, cFMS kinase, pp60c-SRc kinase and HIV-1 integrase. Synonyms: Alutenusin; MS 341; MS-341; MS341. Grades: ≥98%. CAS No. 31186-12-6. Molecular formula: C15H14O6. Mole weight: 290.27. | |
| Ambenonium dichloride | Ambenonium dichloride is an extremely selective, potent and rapidly reversible inhibitor of acetylcholinesterase (AChE) with IC50 value of 0.000698 μM. It is used in the discovery and design of ApoE4 (apolipoprotein E4) inhibitors. It has biological activity showing against Alzheimer's disease. Uses: Parasympathomimetics. Synonyms: Benzenemethanaminium, N,N'-[(1,2-dioxo-1,2-ethanediyl)bis(imino-2,1-ethanediyl)]bis[2-chloro-N,N-diethyl-, chloride (1:2); [Oxalylbis(iminoethylene)]bis[(o-chlorobenzyl)diethylammonium chloride]; Ammonium, [oxalylbis(iminoethylene)]bis[(o-chlorobenzyl)diethyl-, dichloride; Benzenemethanaminium, N,N'-[(1,2-dioxo-1,2-ethanediyl)bis(imino-2,1-ethanediyl)]bis[2-chloro-N,N-diethyl-, dichloride; Ambenonium chloride; Ambestigmin chloride; Misuran; Mysuran; Mysuran chloride; Mytelase; Mytelase chloride; N,N'-Bis-(2-diethylaminoethyl)oxamide bis-2-chlorobenzylchloride; N,N'-Bis-2-[(2-chlorobenzyl)diethylammonium chloride]-ethyloxamide; Oxamizil; Oxazil; Oxazyl; Win 8077. Grades: ≥99%. CAS No. 115-79-7. Molecular formula: C28H42Cl4N4O2. Mole weight: 608.48. | |
| Anatoxin-a | Anatoxin-a (ATX-a) is a neurotoxic alkaloid. Anatoxin-a acts as both a nicotinic acetylcholine receptor (nAChR) agonist and an Acetylcholinesterase (AChE) inhibitor [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: ATX-a. CAS No. 64285-06-9. Pack Sizes: 1 mg. Product ID: HY-W795027. | |
| AP2238 | AP2238 is a inhibitor of both acetylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation. Uses: Cholinesterase inhibitors. Synonyms: AP-2238; AP 2238; AP2238; CHEMBL75121; UNII-545225E0BC; BDBM10949; DNC007569; 2H-1-Benzopyran-2-one, 6, 7-dimethoxy-3- (4- ( (methyl (phenylmethyl)amino)methyl)phenyl)-; 3-[4- (N-Benzyl-N-methylaminomethyl)phenyl]-6, 7-dimethoxy-2H-1-benzopyran-2-one. Grades: 98%. CAS No. 553681-56-4. Molecular formula: C26H25NO4. Mole weight: 415.48. | |
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