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| Product | Description | |
|---|---|---|
| 8-demethylnovobiocic acid C8-methyltransferase | The enzyme is involved in the biosynthesis of the aminocoumarin antibiotic novobiocin. Group: Enzymes. Synonyms: NovO. Enzyme Commission Number: EC 2.1.1.284. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1891; 8-demethylnovobiocic acid C8-methyltransferase; EC 2.1.1.284; NovO. Cat No: EXWM-1891. |  |
| aklanonic acid methyltransferase | The enzyme from the Gram-positive bacterium Streptomyces sp. C5 is involved in the biosynthesis of the anthracycline daunorubicin. Group: Enzymes. Synonyms: DauC; AAMT. Enzyme Commission Number: EC 2.1.1.288. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1895; aklanonic acid methyltransferase; EC 2.1.1.288; DauC; AAMT. Cat No: EXWM-1895. | |
| fatty-acid O-methyltransferase | Oleic acid is the most effective fatty acid acceptor. Group: Enzymes. Synonyms: fatty acid methyltransferase; fatty acid O-methyltransferase. Enzyme Commission Number: EC 2.1.1.15. CAS No. 37256-89-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1745; fatty-acid O-methyltransferase; EC 2.1.1.15; 37256-89-6; fatty acid methyltransferase; fatty acid O-methyltransferase. Cat No: EXWM-1745. | |
| 2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase | The enzyme from the bacterium Streptomyces carzinostaticus is involved in the biosynthesis of 2-hydroxy-7-methoxy-5-methyl-1-naphthoate. This compound is part of the enediyne chromophore of the antitumor antibiotic neocarzinostatin. In vivo the enzyme catalyses the regiospecific methylation at the 7-hydroxy group of its native substrate 2,7-dihydroxy-5-methyl-1-naphthoate. In vitro it also recognizes other dihydroxynaphthoic acids and catalyses their regiospecific O-methylation. Group: Enzymes. Synonyms: NcsB1; neocarzinostatin O-methyltransferase. Enzyme Commission Number: EC 2.1.1.303. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1911; 2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase; EC 2.1.1.303; NcsB1; neocarzinostatin O-methyltransferase. Cat No: EXWM-1911. | |
| 2-(Benzoylamino)-1-(3-phenylpropyl)-1H-benzimidazole-5-carboxylic Acid | 2-(Benzoylamino)-1-(3-phenylpropyl)-1H-benzimidazole-5-carboxylic Acid is a small molecule that has been reported as a novel histone methyltransferase inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1374601-41-8. Pack Sizes: 1mg, 5mg. Molecular Formula: C24H21N3O3, Molecular Weight: 399.44. US Biological Life Sciences. |  Worldwide |
| 2-[ (Benzoylimino) (methylthio) methyl]hydrazide Benzoic Acid | 2-[ (Benzoylimino) (methylthio) methyl]hydrazide Benzoic Acid is an intermediate in synthesizing 1- β-D-Ribofuranosyl-3-aminocarbonyl Guandinine (R415500), which is an impurity of 5-Azacytidine (A796000). 5-Azacytidine is a potent growth inhibitor and cytotoxic agent. 5-Azacytidine acts as a demethylating agent by inhibiting DNA methyltransferase. Group: Biochemicals. Grades: Highly Purified. CAS No. 74074-45-6. Pack Sizes: 25g, 50g. Molecular Formula: C16H15N3O2S. US Biological Life Sciences. | Worldwide |
| 2-ketoarginine methyltransferase | The enzyme is involved in production of the rare amino acid 3-methylarginine, which is used by the epiphytic bacterium Pseudomonas syringae pv. syringae as an antibiotic against the related pathogenic species Pseudomonas syringae pv. glycinea. Group: Enzymes. Synonyms: mrsA (gene name). Enzyme Commission Number: EC 2.1.1.243. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1846; 2-ketoarginine methyltransferase; EC 2.1.1.243; mrsA (gene name). Cat No: EXWM-1846. | |
| 2'-O-Methyl-5-methyluridine 5'-triphosphate | 2'-O-Methyl-5-methyluridine 5'-triphosphate is a pivotal element for studying the captivating realm of RNA modifications. Profoundly influencing diverse cellular processes, this exquisite modified nucleotide assuming a paramount role in unraveling the enigmatic function of methylated RNA. As a versatile substrate for RNA-modifying enzymes, it unleashes unprecedented opportunities to scrutinize mesmeric methyltransferase activities and decode the multifaceted impact of this modification on the intricate structure and myriad functions of RNA. Synonyms: (((2R,3R,4R,5R)-3-Hydroxy-4-methoxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl)triphosphoric acid. CAS No. 444789-41-7. Molecular formula: C11H19N2O15P3. Mole weight: 512.19. |  |
| 3-O-Methyldopa monohydrate | 3-O-Methyldopa monohydrate (3-Methoxy-L-tyrosine monohydrate) is a significant metabolite of L-DOPA produced through the action of catechol O-methyltransferase (COMT). Unlike its precursor, 3-O-Methyldopa does not serve as a substrate or inhibitor of L-amino acid decarboxylase activity. Additionally, the inhibition of COMT can amplify the anti-Parkinson effects of L-DOPA. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 3-Methoxy-L-tyrosine monohydrate; 3-O-Methyl-L-DOPA monohydrate. CAS No. 200630-46-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W012264. |  |
| 3-O-Methyl-L-DOPA-d3 Methyl Ester | Protected labeled 3-O-Methyl-L-DOPA. 3-O-Methyl-L-DOPA is the major metabolite of L-DOPA via catechol O-methyltransferase (COMT). 3-Methoxy-L-tyrosine is neither a substrate for nor an inhibitor of L-amino acid decarboxylase activity. Inhibition of COMT enhances the anti-Parkinson activity of L-DOPA. Group: Biochemicals. Alternative Names: 3-Methoxy-d3-L-tyrosine Methyl Ester. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| 3-O-Methyl-L-DOPA-d3 Monohydrate | Labeled 3-O-Methyl-L-DOPA. 3-O-Methyl-L-DOPA is the major metabolite of L-DOPA via catechol O-methyltransferase (COMT). 3-Methoxy-L-tyrosine is neither a substrate for nor an inhibitor of L-amino acid decarboxylase activity. Inhibition of COMT enhances the anti-Parkinson activity of L-DOPA. Group: Biochemicals. Alternative Names: 3-(Methoxy-d3)-L-tyrosine Monohydrate; 3-(Methoxy-d3)-4-hydroxyphenylalanine Monohydrate; 3-(Methoxy-d3)-DOPA Monohydrate; 3-(Methoxy-d3)-L-tyrosine Monohydrate; 3-O-(Methyl-d3)dopa Monohydrate; L-3-(Methoxy-d3)-4-hydroxy-phenylalanine Monohydrate; L-3-O-(Methyl-d3)-DOPA Monohydrate; L-4-Hydroxy-3-(methoxy-d3)phenylalanine Monohydrate. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| 3-O-Methyl-L-DOPA Methyl Ester | Protected 3-O-Methyl-L-DOPA. 3-O-Methyl-L-DOPA is the major metabolite of L-DOPA via catechol O-methyltransferase (COMT). 3-Methoxy-L-tyrosine is neither a substrate for nor an inhibitor of L-amino acid decarboxylase activity. Inhibition of COMT enhances the anti-Parkinson activity of L-DOPA. Group: Biochemicals. Alternative Names: 3-Methoxy-L-tyrosine Methyl Ester. Grades: Highly Purified. CAS No. 78148-37-5. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| 3-O-Methyl-L-DOPA Monohydrate | 3-O-Methyl-L-DOPA is the major metabolite of L-DOPA via catechol O-methyltransferase (COMT). 3-Methoxy-L-tyrosine is neither a substrate for nor an inhibitor of L-amino acid decarboxylase activity. Inhibition of COMT enhances the anti-Parkinson activity of L-DOPA. Group: Biochemicals. Alternative Names: 3-Methoxy-L-tyrosine Monohydrate; 3-Methoxy-4-hydroxyphenylalanine Monohydrate; 3-Methoxy-DOPA Monohydrate; 3-Methoxy-L-tyrosine Monohydrate; 3-O-Methyldopa Monohydrate; L-3-Methoxy-4-hydroxyphenylalanine Monohydrate; L-3-O-Methyl-DOPA Monohydrate; L-4-Hydroxy-3-methoxyphenylalanine Monohydrate. Grades: Highly Purified. CAS No. 200630-46-2. Pack Sizes: 10mg, 25mg, 50mg. US Biological Life Sciences. | Worldwide |
| 5-(Acetylamino)-2-hydroxybenzoic acid | N-Acetyl Mesalazine is a metabolite of Mesalazine. It is a Salicylic Acid derivative. It is an inhibitor of recombinant human thiopurine methyltransferase (hTPMT). Synonyms: 5-acetamido-2-hydroxybenzoic acid. Grades: > 95 %. CAS No. 51-59-2. Molecular formula: C9H9NO4. Mole weight: 195.17. | |
| 5-Methyl-dCTP | 5-Methyl-dCTP, a paramount component within the biomedical industry, is deeply engrossed in DNA synthesis. During cell division and replication, it becomes embedded into DNA and is implemented by DNA methyltransferases to methylate CpG islands. Its potential for detection and quantification of DNA methylation in diverse diseases, such as cancer and neurodegenerative disorders, makes it a popular choice. Synonyms: 5-Methyl-2'-deoxycytidine-5'-Triphosphate; m5-dCTP; 5-m-dCTP; 5m-dCTP; 5-methyldeoxycytidine triphosphate. Grades: ≥ 95% by HPLC. CAS No. 22003-12-9. Molecular formula: C10H18N3O13P3 (free acid). Mole weight: 481.18 (free acid). | |
| 7-Methylguanosine 5'-triphosphate sodium salt | 7-Methylguanosine 5'-triphosphate sodium salt, a highly indispensable reagent in the field of biomedicine, finds extensive utilization across diverse applications. Functioning as a potent guanosine triphosphate (GTP) analogue, it assumes a pivotal role in the processes of mRNA capping, RNA processing, and RNA splicing. Its auxiliary role involves facilitating the exploration of RNA-protein interactions while also serving as a substrate for RNA methyltransferases. Group: Heterocyclic organic compound. Alternative Names: 7-Methylguanosine 5-triphosphate sodium salt, 104809-18-9, M6133_SIGMA, CTK8E9676, 7-Methylguanosine 5 inverted exclamation marka-triphosphate sodium salt. CAS No. 104809-18-9. Molecular formula: C11H18N5O14P3·xNa+. Mole weight: 537.21 (free acid basis). Purity: ≥85%. IUPACName: sodium;[[[(2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxido-3,6-dihydropurin-9-ium-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] hydrogen phosphate. Catalog: ACM104809189. |  |
| 7-Methylguanosine 5'-triphosphate sodium salt | 7-Methylguanosine 5'-triphosphate sodium salt, a highly indispensable reagent in the field of biomedicine, finds extensive utilization across diverse applications. Functioning as a potent guanosine triphosphate (GTP) analogue, it assumes a pivotal role in the processes of mRNA capping, RNA processing, and RNA splicing. Its auxiliary role involves facilitating the exploration of RNA-protein interactions while also serving as a substrate for RNA methyltransferases. Molecular formula: C11H18N5O14P3·xNa. Mole weight: 537.21 (free acid). | |
| AMI-1 | AMI-1 is a cell-permeable inhibitor which inhibits protein arginine N-methyltransferase (PRMT) activity with IC50 of 8.81 μM for PRMT1 and IC50 of 3.04 μM for Hmt1p in vitro. MI-1 does not compete for the AdoMet (S-adenosyl-L-methionine; SAM) binding site and exhibits minimal effects on both SET (Sub39H1, Suv39H2, SET7) and non-SET (DOT1) lysine N-methyltransferases. Furthermore, AMI-1 prevents in vivo arginine methylation of cellular proteins and can modulate nuclear receptor-regulated transcription from estrogen and androgen response elements, thus operating as a brake on certain hormone actions. Synonyms: 7,7'-(Carbonyldiimino)bis[4-hydroxy-2-naphthalenesulfonic acid] disodium salt; 5,5'-Dihydroxy-2,2'-dinaphthylcarbamide-7,7'-disulfonic acid disodium salt; 6,6'-Ureylenebis(1-naphthol-3-sulfonic acid) disodium salt; 7,7'-Ureylenebis(4-hydroxy-2-naphthalenesulfonic acid) disodium salt; Carbonyl J disodium salt; I Acid Urea disodium salt; N,N'-Bis(5-hydroxy-7-sulfo-2-naphthyl)urea disodium salt; N,N'-Bis(7-sulfo-5-hydroxy-2-naphthyl)urea disodium salt; N,N'-Bis[1-hydroxy-3-sulfonaphthyl(6)]urea disodium salt; N,N'-Bis[1-oxy-3-sulfonaphthyl(6)]urea disodium salt; AMI-1 sodium salt; AMI 1; AMI1; J Acid Urea disodium salt. Grades: ≥98%. CAS No. 20324-87-2. Molecular formula: C21H14N2Na2O9S2. Mole weight: 548.45. | |
| anthranilate N-methyltransferase | Involved in the biosynthesis of acridine alkaloids in plant tissues. Group: Enzymes. Synonyms: anthranilic acid N-methyltransferase. Enzyme Commission Number: EC 2.1.1.111. CAS No. 123779-15-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1710; anthranilate N-methyltransferase; EC 2.1.1.111; 123779-15-7; anthranilic acid N-methyltransferase. Cat No: EXWM-1710. | |
| benzoate O-methyltransferase | While the enzyme from the plant Zea mays is specific for benzoate, the enzymes from Arabidopsis species and Clarkia breweri also catalyse the reaction of EC 2.1.1.274, salicylate 1-O-methyltransferase. In snapdragon (Antirrhinum majus) two isoforms are found, one specific for benzoate and one that is also active towards salicylate. The volatile product is an important scent compound in some flowering species. Group: Enzymes. Synonyms: BAMT; S-adenosyl-L-methionine:benzoic acid carboxyl methyltransferase. Enzyme Commission Number: EC 2.1.1.273. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1879; benzoate O-methyltransferase; EC 2.1.1.273; BAMT; S-adenosyl-L-methionine:benzoic acid carboxyl methyltransferase. Cat No: EXWM-1879. | |
| caffeate O-methyltransferase | 3,4-Dihydroxybenzaldehyde and catechol can act as acceptors, but more slowly. Group: Enzymes. Synonyms: caffeate methyltransferase; caffeate 3-O-methyltransferase; S-adenosyl-L-methionine:caffeic acid-O-methyltransferase. Enzyme Commission Number: EC 2.1.1.68. CAS No. 50936-45-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1969; caffeate O-methyltransferase; EC 2.1.1.68; 50936-45-3; caffeate methyltransferase; caffeate 3-O-methyltransferase; S-adenosyl-L-methionine:caffeic acid-O-methyltransferase. Cat No: EXWM-1969. | |
| cyclopropane-fatty-acyl-phospholipid synthase | The enzyme adds a methylene group across the 9,10 position of a Δ9-olefinic acyl chain in phosphatidylethanolamine or, more slowly, phosphatidylglycerol or phosphatidylinositol, forming a cyclopropane derivative (cf. EC 2.1.1.16 methylene-fatty-acyl-phospholipid synthase). Group: Enzymes. Synonyms: cyclopropane synthetase; unsaturated-phospholipid methyltransferase; cyclopropane synthase; cyclopropane fatty acid synthase; cyclopropane fatty acid synthetase; CFA synthase. Enzyme Commission Number: EC 2.1.1.79. CAS No. 51845-48-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1980; cyclopropane-fatty-acyl-phospholipid synthase; EC 2.1.1.79; 51845-48-8; cyclopropane synthetase; unsaturated-phospholipid methyltransferase; cyclopropane synthase; cyclopropane fatty acid synthase; cyclopropane fatty acid synthetase; CFA synthase. Cat No: EXWM-1980. | |
| Decitabine Impurity 3 | 2-Deoxy-D-erythro-pentofuranose 3,5-di-p-toluate is an impurity of Decitabine, a DNA hypomethylating agent that is used to treat various forms of cancer, such as myelogeneous leukemia and metastatic lung cancerBy inhibiting DNA methyltransferase, Decitabine silences the tumour suppressor genes and, consequently, "normalizing" gene expression in cancerous cells. Synonyms: rac-2-Deoxy-D-erythro-pentofuranose 3,5-Di-p-toluate; p-Toluic Acid 3,5-Diester with 2-Deoxy-D-erythro-pentofuranose. Grades: > 95%. CAS No. 17117-72-5. Molecular formula: C21H22O6. Mole weight: 370.4. | |
| demethylrebeccamycin-D-glucose O-methyltransferase | Catalyses the last step in the biosynthesis of rebeccamycin, an indolocarbazole alkaloid produced by the bacterium Lechevalieria aerocolonigenes. The enzyme is able to use a wide variety substrates, tolerating variation on the imide heterocycle, deoxygenation of the sugar moiety, and even indolocarbazole glycoside anomers. The enzyme is a member of the general acid/base-dependent O-methyltransferase family. Group: Enzymes. Synonyms: RebM. Enzyme Commission Number: EC 2.1.1.164. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1761; demethylrebeccamycin-D-glucose O-methyltransferase; EC 2.1.1.164; RebM. Cat No: EXWM-1761. | |
| dimethylamine-corrinoid protein Co-methyltransferase | The enzyme, which catalyses the transfer of a methyl group from dimethylamine to a dimethylamine-specific corrinoid protein (MtbC), is involved in methanogenesis from dimethylamine. The enzyme contains the unusual amino acid pyrrolysine. Methylation of the corrinoid protein requires the central cobalt to be in the Co(I) state. During methylation the cobalt is oxidized to the Co(III) state. The methylated corrinoid protein is substrate for EC 2.1.1.247, methylated methylamine-specific corrinoid protein:coenzyme M methyltransferase. Group: Enzymes. Synonyms: mtbB (gene name); dimethylamine methyltransferase. Enzyme Commission Number: EC 2.1.1.249. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1852; dimethylamine-corrinoid protein Co-methyltransferase; EC 2.1.1.249; mtbB (gene name); dimethylamine methyltransferase. Cat No: EXWM-1852. | |
| EDA-m7GDP - 5-FAM | EDA-m7GDP is a small molecule used in the biomedicine industry for the study of RNA processing and modification. It serves as a substrate analog for RNA cap methyltransferase and is used to investigate the role of the cap structure and its modification in RNA processing. EDA-m7GDP is also used in the development of potential antiviral drugs as it inhibits viral RNA cap formation. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with ATTO 5FAM, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C35H33N7O18P2(free acid). Mole weight: 901.63 (free acid). | |
| EDA-m7GDP - ATTO-Rho14 | EDA-m7GDP - ATTO-Rho14 is a specialized biomedical product used in the study of RNA capping enzymes. Specifically, it is used as a fluorescent substrate for monitoring the activity of RNA cap guanine-N7 methyltransferase (RNMT) and other related enzymes. This product can potentially aid in the development of new drugs targeting RNA capping enzymes and diseases related to their dysfunction. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with ATTO Rho14, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C55H64Cl4N10O15P2(free acid). Mole weight: 1306.28 (free acid). | |
| EDA-m7GDP - Texas Red | EDA-m7GDP - Texas Red is a fluorescent probe widely used in biomedicine to study RNA cap structures and reveal functional characteristics of RNA methyltransferase activity. It can be used to detect methylated guanine nucleotides in cells and tissues, aiding the development of new therapies for various viral diseases. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with Texas Red, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C51H62N10O19P2S2-(free acid). Mole weight: 1245.17 (free acid). | |
| EDA-m7GTP - ATTO-MB2 | EDA-m7GTP - ATTO-MB2 is a fluorescent substrate used for studying RNA capping enzymes. It is structurally similar to m7GTP, a cap structure found at the 5' end of eukaryotic messenger RNA (mRNA). This product can be used for fluorescence polarization assays to measure the activity of RNA capping enzymes such as RNA guanine-7 methyltransferase (RNMT). Understanding the activity of these enzymes can provide insight into diseases that rely on mRNA modification, such as cancer and viral infections. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-triphosphate, labeled with ATTO-MB2, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C33H43N10O16P3S (free acid). Mole weight: 960.74 (free acid). | |
| EDA-m7GTP - DY-485XL | EDA-m7GTP - DY-485XL is a biomedical product used in studying RNA modifications. It acts as a substrate analog for RNA cap methyltransferases, allowing for the identification and analysis of m7G modified RNAs. This product aids in the understanding of mRNA processing, translation, and the role of m7G modifications in various diseases such as cancer and neurological disorders. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-triphosphate, labeled with DY 485XL, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C39H52N9O21P3S (free acid). Mole weight: 1107.87 (free acid). | |
| EDA-m7GTP - OYSTER-656 | EDA-m7GTP is a modified nucleotide analog extensively used in the biomedical industry for its potential in studying RNA methylation and epitranscriptomics. It is capable of binding RNA methyltransferases and RNA-binding proteins is aiding in the investigation of methyltransferase activity and RNA modification processes. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-triphosphate, labeled with OYSTER 656, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C14H24N7O15P3- OYSTER 656 (free acid). Mole weight: 1340.31 (free acid). | |
| (E,E)-Farnesyl Thioacetate | (E,E)-Farnesyl Thioacetate, an acetate derivative of (E,E)-Farnesyl Thiol, has inhibitory activity against human isoprenylcysteine carboxyl methyltransferase (Icmt) protein. Synonyms: Ethanethioic Acid S-[(2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrien-1-yl] Ester; Ethanethioic Acid S-[(2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrienyl] Ester; S-[(2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrien-1-yl] ethanethioate. Grades: ≥95%. CAS No. 340701-35-1. Molecular formula: C17H28OS. Mole weight: 280.47. | |
| Entacapone 3-b-D-glucuronide | Entacapone 3-b-D-glucuronide is a metabolite of Entacapone, which is a selective and reversible inhibitor of the enzyme catechol-O-methyltransferase (COMT) used in combination with other medications for the treatment of Parkinson's disease. Synonyms: β-D-Glucopyranosiduronic acid, 5-[(1E)-2-cyano-3-(diethylamino)-3-oxo-1-propen-1-yl]-2-hydroxy-3-nitrophenyl; 5-[(1E)-2-Cyano-3-(diethylamino)-3-oxo-1-propen-1-yl]-2-hydroxy-3-nitrophenyl β-D-glucopyranosiduronic acid; β-D-Glucopyranosiduronic acid, 5-[(1E)-2-cyano-3-(diethylamino)-3-oxo-1-propenyl]-2-hydroxy-3-nitrophenyl; β-D-Glucopyranosiduronic acid, 5-[2-cyano-3-(diethylamino)-3-oxo-1-propenyl]-2-hydroxy-3-nitrophenyl, (E)-; Entacapone 3-β-D-glucuronide. Grades: ≥95%. CAS No. 158069-75-1. Molecular formula: C20H23N3O11. Mole weight: 481.41. | |
| EPZ011989 trifluoroacetate | EPZ011989 trifluoroacetate is the trifluoroacetate salt form of EPZ011989. EPZ011989 is a potent and orally bioavailable inhibitor that specifically targets the protein methyltransferase Enhancer of Zeste Homolog 2 (EZH2), with significant tumor growth in. Synonyms: EPZ011989 TFA salt; EPZ011989 TFA; EPZ 011989 TFA; EPZ-011989 TFA; N-[ (4, 6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-3-[ethyl-[4-[2-methoxyethyl (methyl)amino]cyclohexyl]amino]-2-methyl-5- (3-morpholin-4-ylprop-1-ynyl)benzamide; 2, 2, 2-trifluoroacetic acidEPZ011989 (trifluoroacetate). CAS No. 1598383-41-5. Molecular formula: C37H52F3N5O6. Mole weight: 719.83. | |
| Farnesoic acid/(2E,6E)-3,7,11-Trimethyldodeca-2,6,10-trienoic acid | Farnesoic acid ((2E,6E)-3,7,11-trimethyldodeca-2,6,10-trienoic acid) is the substrate of farnesoic acid O-methyltransferase which produces the crustacean reproductive hormone, methyl farnesoate (MF). MF is responsible for enhancing reproductive maturation, maintaining juvenile morphology, and influencing male sex determination. Farnesoic acid also inhibits filiment formation in C. albicans. Synonyms: (2E,6E)-3,7,11-Trimethyldodeca-2,6,10-trienoic acid; (2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrienoic acid; Farnesoic acid. CAS No. 462-11-3. Product ID: PAP-0100. Molecular formula: C15H24O2. Mole weight: 236.18. Category: Biochemical Reagents. Product Keywords: Other Active Pharmaceutical Ingredients; PAP-0100; Farnesoic acid/(2E,6E)-3,7,11-Trimethyldodeca-2,6,10-trienoic acid; 462-11-3; (2E,6E)-3,7,11-Trimethyldodeca-2,6,10-trienoic acid; (2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrienoic acid; Farnesoic acid. Chemical Name: (E,E)-Farnesoic Acid. Grade: Pharmaceutical grade. Stability and Storage Conditions: -20 °C or below. |  |
| Homocysteine Methyltransferase, Recombinant | Homocysteine (Hcy) is a thiol-containing amino acid formed from methionine during S-adenosylmethionine-dependent transmethylation reactions. It has been demonstrated that even mild or moderately elevated levels of Hcyalso increase the risk of atherosclerosis of the coronary, cerebral andperipheral arteries and cardiovascular disease. And currently the hcy level isregarded as the biomarker for cardiovascular disease diagnosis all over the world. Methyltransferases are a large group of enzymes that all methylate their substrates but can be split into several subclasses based on their structural features. the most common class of methyltransferases is class i, all of which...hylase; homocysteine methyltransferase; homocysteine transmethylase; L-homocysteine S-methyltransferase; S-adenosyl-L-methionine:L-homocysteine methyltransferase; S-adenosylmethionine-homocysteine transmethylase; S-adenosylmethionine:homocysteine methyltransferase; EC 2.1.1.10. Enzyme Commission Number: EC 2.1.1.10. Purity: >90% (SDS-PAGE test). Mole weight: About 51kDa (SDS-PAGE detection). Activity: >70U/mg. Appearance: White powder, lyophilized. Storage: Redissolved in 30% glycerol, 4°C, store at -20°C for long-term preservation, Avoid multiple freeze-thaw cycles. Form: Freeze dried powder. homocysteine S-methyltransferase; S-adenosylmethionine homocysteine transmethy | |
| Homovanillic Acid Sulfate Sodium Salt | A metabolite of Dihydroxyphenylacetic Acid (DOPAC) by catechol O-methyltransferase. Group: Biochemicals. Alternative Names: 3-Methoxy-4-(sulfooxy)-benzeneacetic Acid Disodium Salt. Grades: Highly Purified. CAS No. 38339-06-9. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Homovanillic Acid Sulfate Sodium Salt-d3 | A labeled metabolite of Dihydroxyphenylacetic Acid (DOPAC) by catechol O-methyltransferase. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| indolepyruvate C-methyltransferase | The enzyme, characterized from the bacterium Streptomyces griseus, is involved in the biosynthesis of the antibacterial drug indolmycin. Group: Enzymes. Synonyms: ind1 (gene name); indolepyruvate methyltransferase; indolepyruvate 3-methyltransferase; indolepyruvic acid methyltransferase; S-adenosyl-L-methionine:indolepyruvate C-methyltransferase. Enzyme Commission Number: EC 2.1.1.47. CAS No. 54576-88-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1951; indolepyruvate C-methyltransferase; EC 2.1.1.47; 54576-88-4; ind1 (gene name); indolepyruvate methyltransferase; indolepyruvate 3-methyltransferase; indolepyruvic acid methyltransferase; S-adenosyl-L-methionine:indolepyruvate C-methyltransferase. Cat No: EXWM-1951. | |
| jasmonate O-methyltransferase | 9,10-Dihydrojasmonic acid is a poor substrate for the enzyme. The enzyme does not convert 12-oxo-phytodienoic acid (a precursor of jasmonic acid), salicylic acid, benzoic acid, linolenic acid or cinnamic acid into their corresponding methyl esters. Enzyme activity is inhibited by the presence of divalent cations, e.g., Ca2+, Cu2+, Mg2+ and Zn2+. Group: Enzymes. Synonyms: jasmonic acid carboxyl methyltransferase. Enzyme Commission Number: EC 2.1.1.141. CAS No. 346420-58-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1737; jasmonate O-methyltransferase; EC 2.1.1.141; 346420-58-4; jasmonic acid carboxyl methyltransferase. Cat No: EXWM-1737. | |
| juvenile hormone-III synthase | The enzyme, found in insects, is involved in the synthesis of juvenile hormone III, a sesquiterpenoid that regulates several processes including embryonic development, metamorphosis, and reproduction, in many insect species. Group: Enzymes. Synonyms: farnesoic acid methyltransferase; juvenile hormone acid methyltransferase; JHAMT. Enzyme Commission Number: EC 2.1.1.325. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1933; juvenile hormone-III synthase; EC 2.1.1.325; farnesoic acid methyltransferase; juvenile hormone acid methyltransferase; JHAMT. Cat No: EXWM-1933. | |
| loganate O-methyltransferase | Also acts on secologanate. Methylates the 11-carboxy group of the monoterpenoid loganate. Group: Enzymes. Synonyms: loganate methyltransferase; S-adenosyl-L-methionine:loganic acid methyltransferase. Enzyme Commission Number: EC 2.1.1.50. CAS No. 39391-10-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1954; loganate O-methyltransferase; EC 2.1.1.50; 39391-10-1; loganate methyltransferase; S-adenosyl-L-methionine:loganic acid methyltransferase. Cat No: EXWM-1954. | |
| malonyl-[acyl-carrier protein] O-methyltransferase | Involved in an early step of biotin biosynthesis in Gram-negative bacteria. This enzyme catalyses the transfer of a methyl group to the ω-carboxyl group of malonyl-[acyl-carrier protein] forming a methyl ester. The methyl ester is recognized by the fatty acid synthetic enzymes, which process it via the fatty acid elongation cycle to give pimelyl-[acyl-carrier-protein] methyl ester. While the enzyme can also accept malonyl-CoA, it has a much higher activity with malonyl-[acyl-carrier protein]. Group: Enzymes. Synonyms: BioC. Enzyme Commission Number: EC 2.1.1.197. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1796; malonyl-[acyl-carrier protein] O-methyltransferase; EC 2.1.1.197; BioC. Cat No: EXWM-1796. | |
| Methotrexate EP Impurity L | An impurity of Methotrexate, an antimetabolite and immunosuppressant used in chemotherapy and auto-immune diseases. This impurity also acts as an inhibitor of human DNA methyltransferase. Synonyms: N-(4-(Methylamino)benzoyl)-L-glutamic acid; N-(p-(Methylamino)benzoyl)glutamic acid; (p-Methylaminobenzoyl)-L-glutamic Acid; N-[p-(Methylamino)benzoyl]-L-glutamic acid; NSC 138419. Grades: > 95%. CAS No. 52980-68-4. Molecular formula: C13H16N2O5. Mole weight: 280.28. | |
| methylamine-corrinoid protein Co-methyltransferase | The enzyme, which catalyses the transfer of a methyl group from methylamine to a methylamine-specific corrinoid protein (MtmC), is involved in methanogenesis from methylamine. The enzyme contains the unusual amino acid pyrrolysine. Methylation of the corrinoid protein requires the central cobalt to be in the Co(I) state. During methylation the cobalt is oxidized to the Co(III) state. The methylated corrinoid protein is substrate for EC 2.1.1.247, methylated methylamine-specific corrinoid protein:coenzyme M methyltransferase. Group: Enzymes. Synonyms: mtmB (gene name); monomethylamine methyltransferase. Enzyme Commission Number: EC 2.1.1.248. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1851; methylamine-corrinoid protein Co-methyltransferase; EC 2.1.1.248; mtmB (gene name); monomethylamine methyltransferase. Cat No: EXWM-1851. | |
| methylarsonate reductase | The product, methylarsonite, is biologically methylated by EC 2.1.1.137, arsenite methyltransferase, to form cacodylic acid. Group: Enzymes. Synonyms: MMA(V) reductase. Enzyme Commission Number: EC 1.20.4.2. CAS No. 254889-62-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1241; methylarsonate reductase; EC 1.20.4.2; 254889-62-8; MMA(V) reductase. Cat No: EXWM-1241. | |
| methylornithine synthase | The enzyme is a member of the superfamily of S-adenosyl-L-methionine-dependent radical (radical AdoMet) enzymes. Binds a [4Fe-4S] cluster that is coordinated by 3 cysteines and an exchangeable S-adenosyl-L-methionine molecule. The reaction is part of the biosynthesis pathway of pyrrolysine, a naturally occurring amino acid found in some archaeal methyltransferases. Group: Enzymes. Synonyms: PylB. Enzyme Commission Number: EC 5.4.99.58. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5601; methylornithine synthase; EC 5.4.99.58; PylB. Cat No: EXWM-5601. | |
| N6-Methyladenosine-5'-triphosphate lithium salt | N6-Methyladenosine-5'-triphosphate lithium salt is an exceptionally robust stimulant of methyltransferases, standing as a pivotal constituent employed for the scrutiny of RNA modifications. Synonyms: 6-Me-ATP. Grades: ≥ 95%. Molecular formula: C11H18N5O13P3·xLi. Mole weight: 521.21 (free acid). | |
| N-Acetyl-5-aminosalicylic Acid (5-Acetylamino-2-hydroxybenzoic Acid. 5-Acetamidosalicylic Acid. N-Acetylmesalamine) | A Salicylic Acid derivative. Inhibitor of recombinant human thiopurine methyltransferase (hTPMT). Group: Biochemicals. Alternative Names: 5-Acetylamino-2-hydroxybenzoic Acid5-Acetamidosalicylic AcidN-Acetylmesalamine. Grades: Highly Purified. CAS No. 51-59-2. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| N-Acetyl-5-aminosalicylic Acid-methyl-d3 | A labeled Salicylic Acid derivative. Inhibitor of recombinant human thiopurine methyltransferase (hTPMT). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| N-Acetyl-L-Tyrosine | N-acetyl-L-tyrosine is an N-acetyltyrosine in which the chiral centre has L configuration. It has a role as an EC 2.1.1.4 (acetylserotonin O-methyltransferase) inhibitor, a biomarker and a human urinary metabolite. It is a N-acyl-L-tyrosine and a N-acetyltyrosine. It is a conjugate acid of a N-acetyl-L-tyrosinate. CAS No. 537-55-3. Product ID: PAP-0010. Molecular formula: C11H13NO4. Category: Amino acid. Product Keywords: Amino Acid Series; N-Acetyl-L-Tyrosine; PAP-0010; Amino acid; C11H13NO4; 537-55-3. Color: White to Off-White. EC Number: 208-671-3. Physical State: Crystalline. Solubility: H2O: soluble25mg/mL. Storage: Sealed in dry,Room Temperature. Applications: N-Acetyl-L-Tyrosine is an important fine organic chemical intermediate, widely used in medicine, pesticides, chemical industry and other fields. Boiling Point: 364.51°C (rough estimate). Melting Point: 149-152 °C(lit.). Density: 1.2446 (rough estimate). Product Description: N-Acetyl-L-Tyrosine is an important fine organic chemical intermediate, widely used in medicine, pesticides, chemical industry and other fields. | |
| N-acetyl-S-farnesyl-L-cysteine | N-acetyl-S-farnesyl-L-cysteine is an inhibitor of the isoprenylated protein methyltransferase. Uses: Enzyme inhibitors. Synonyms: AFC; Ac-Cys(farnesyl)-OH; (2R)-2-acetamido-3-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trienyl]sulfanylpropanoic acid. Grades: ≥98%. CAS No. 135304-07-3. Molecular formula: C20H33NO3S. Mole weight: 367.5. | |
| N-acetyl-S-geranylgeranyl-L-cysteine | N-acetyl-S-geranylgeranyl-L-Cysteine is an inhibitor of the isoprenylated protein methyltransferase. Synonyms: AGGC; (2R)-2-acetamido-3-[(2E,6E,10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraenyl]sulfanylpropanoic acid. Grades: ≥95%. CAS No. 139332-94-8. Molecular formula: C25H41NO3S. Mole weight: 435.7. | |
| Native Protein Methylase II | Methylation of proteins is one of the key reactions in the post-translational modification of protein amino acid residues in the cell. It has been established that the basic and acidic amino acid residues of certain proteins are methylated in vivo. Protein methylase II methylates the free carboxyl groups of dicarboxylic acid residues in a protein molecule. Existence of this enzyme, in mammalian tissues, was first reported by Liss and Edelstein. Protein methylase II from ox brain has been purified by Iqbal and Steenson. Group: Enzymes. Synonyms: S-adenosylmethionine:protein Carboxyl O-methyltransferase; EC 2.1.1.24; Protein Methylase II. Enzyme Commission Number: EC 2.1.1.24. Protein Methylase II. S-adenosylmethionine:protein Carboxyl O-methyltransferase; EC 2.1.1.24; Protein Methylase II. Cat No: NATE-0895. | |
| phenylpyruvate C3-methyltransferase | The enzyme from the bacterium Streptomyces hygroscopicus NRRL3085 is involved in synthesis of the nonproteinogenic amino acid (2S,3S)-β-methyl-phenylalanine, a building block of the antibiotic mannopeptimycin. Group: Enzymes. Synonyms: phenylpyruvate Cβ-methyltransferase; phenylpyruvate methyltransferase; mppJ (gene name). Enzyme Commission Number: EC 2.1.1.281. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1888; phenylpyruvate C3-methyltransferase; EC 2.1.1.281; phenylpyruvate Cβ-methyltransferase; phenylpyruvate methyltransferase; mppJ (gene name). Cat No: EXWM-1888. | |
| protein N-terminal methyltransferase | This enzyme methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys after the initiator L-methionine is cleaved. When the terminal amino acid is L-proline, the enzyme catalyses two successive methylations of its α-amino group. When the first amino acid is either L-alanine or L-serine, the enzyme catalyses three successive methylations.The Pro-Lys in positions 2-3 cannot be exchanged for other amino acids. Group: Enzymes. Synonyms: NMT1 (gene name); METTL11A (gene name). Enzyme Commission Number: EC 2.1.1.244. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1847; protein N-terminal methyltransferase; EC 2.1.1.244; NMT1 (gene name); METTL11A (gene name). Cat No: EXWM-1847. | |
| pyrrolysine-tRNAPyl ligase | In organisms such as Methanosarcina barkeri that incorporate the modified amino acid pyrrolysine (Pyl) into certain methylamine methyltransferases, an unusual tRNAPyl, with a CUA anticodon, can be charged directly with pyrrolysine by this class II aminoacyl-tRNA ligase. The enzyme is specific for pyrrolysine as substrate as it cannot be replaced by lysine or any of the other natural amino acids. Group: Enzymes. Synonyms: PylS; pyrrolysyl-tRNA synthetase. Enzyme Commission Number: EC 6.1.1.26. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5657; pyrrolysine-tRNAPyl ligase; EC 6.1.1.26; PylS; pyrrolysyl-tRNA synthetase. Cat No: EXWM-5657. | |
| RG108 | RG108 is a DNA methyltransferase inhibitor with IC50 value of 115 nM. RG108 can enhance reprogramming of somatic cells to induced pluripotent stem (iPS) cells. Synonyms: N-Phthalyl-L-tryptophan; RG-108; (2S)-2-(1,3-dioxoisoindol-2-yl)-3-(1H-indol-3-yl)propanoic acid. Grades: >98%. CAS No. 48208-26-0. Molecular formula: C19H14N2O4. Mole weight: 334.33. | |
| S-(5'-Adenosyl)-L-methionine Chloride Dihydrochloride | S-(5?-Adenosyl)-L-methionine chloride dihydrochloride (SAM) facilitates the transfer of methyl groups to proteins, lipids and nucleic acids. Methionine adenosyl transferase catalyses the synthesis of SAM from methionine and adenosine triphosphate (ATP). SAM functions to regulate various cellular functions like cell division, cell death, transcription, genetic stability, oxidant/antioxidant balance and polyamine homeostasis. Therapeutically, SAM finds its application as a nutritional supplement in humans for various diseases like osteoarthritis and liver injury. SAM also regulates transsulfuration reactions by binding to the regulatory domain of key enzyme cystathionine- β-synthase (CBS).S-(5?-Adenosyl)-L-methionine chloride dihydrochloride has been used as a medium supplement for S30 cell extract. It also has been used for measuring the interaction with catechol-O-methyltransferase (COMT) by quartz crystal microbalance (QCM), surface plasmon resonance (SPR) and isothermal titration calorimetry (ITC) with supported lipid bilayers and vesicles. Group: Biochemicals. Alternative Names: 5'- [ [ (3S) -3-Amino-3-carboxypropyl] methylsulfonio] -5'-deoxya. Grades: Purified. CAS No. 86867-01-8. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C15H23ClN6O5S·2HCl, Molecular Weight: 507.82. US Biological Life Sciences. | Worldwide |
| salicylate 1-O-methyltransferase | The enzyme, which is found in flowering plants, also has the activity of EC 2.1.1.273, benzoate O-methyltransferase. Group: Enzymes. Synonyms: SAMT; S-adenosyl-L-methionine:salicylic acid carboxyl methyltransferase; salicylate carboxymethyltransferase. Enzyme Commission Number: EC 2.1.1.274. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1880; salicylate 1-O-methyltransferase; EC 2.1.1.274; SAMT; S-adenosyl-L-methionine:salicylic acid carboxyl methyltransferase; salicylate carboxymethyltransferase. Cat No: EXWM-1880. | |
| thetin-homocysteine S-methyltransferase | This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is dimethylsulfonioacetic acid:L-homocysteine S-methyltransferase. Other names in common use include dimethylthetin-homocysteine methyltransferase, and thetin-homocysteine methylpherase. Group: Enzymes. Synonyms: dimethylthetin-homocysteine methyltransferase; thetin-homocysteine methylpherase. Enzyme Commission Number: EC 2.1.1.3. CAS No. 9029-76-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1907; thetin-homocysteine S-methyltransferase; EC 2.1.1.3; 9029-76-9; dimethylthetin-homocysteine methyltransferase; thetin-homocysteine methylpherase. Cat No: EXWM-1907. | |
| trans-Aconitic acid | trans-Aconitic acid is present in normal human urine, and it has been suggested that is present in larger amounts with Reye's syndrome and organic aciduria. trans-Aconitic acid is a substrate of enzyme trans-aconitate 2-methyltransferase. Uses: Scientific research. Group: Natural products. CAS No. 4023-65-8. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-W016813. | |
| trans, trans Farnesylthiosalicylic Acid (FTS, (3,7,11-Trimethyldodeca-2,6,10-trienyl)-2-thiobenzoic Acid) | A potent prenylated protein methyltransferase (PPMTase) inhibitor. Selectively inhibits the growth of human Ha-ras-transformed Rat1 cells in vitro (EC50=7.5uM). Group: Biochemicals. Alternative Names: FTS, (3,7,11-Trimethyldodeca-2,6,10-trienyl)-2-thiobenzoic Acid. Grades: Highly Purified. CAS No. 162520-00-5. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| trimethylamine-corrinoid protein Co-methyltransferase | The enzyme, which catalyses the transfer of a methyl group from trimethylamine to a trimethylamine-specific corrinoid protein (MttC), is involved in methanogenesis from trimethylamine. The enzyme contains the unusual amino acid pyrrolysine. Methylation of the corrinoid protein requires the central cobalt to be in the Co(I) state. During methylation the cobalt is oxidized to the Co(III) state. The methylated corrinoid protein is substrate for EC 2.1.1.247, methylated methylamine-specific corrinoid protein:coenzyme M methyltransferase. Group: Enzymes. Synonyms: mttB (gene name); trimethylamine methyltransferase. Enzyme Commission Number: EC 2.1.1.250. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1854; trimethylamine-corrinoid protein Co-methyltransferase; EC 2.1.1.250; mttB (gene name); trimethylamine methyltransferase. Cat No: EXWM-1854. | |
| tRNA (adenine9-N1)-methyltransferase | The enzyme from Sulfolobus acidocaldarius specifically methylates adenine9 in tRNA. The bifunctional enzyme from Thermococcus kodakaraensis also catalyses the methylation of guanine9 in tRNA (cf. EC 2.1.1.221, tRNA (guanine9-N1)-methyltransferase). Group: Enzymes. Synonyms: Trm10p (ambiguous); tRNA(m1G9/m1A9)-methyltransferase; tRNA(m1G9/m1A9)MTase; TK0422p (gene name); tRNA m1A9-methyltransferase; tRNA m1A9 Mtase. Enzyme Commission Number: EC 2.1.1.218. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1820; tRNA (adenine9-N1)-methyltransferase; EC 2.1.1.218; Trm10p (ambiguous); tRNA(m1G9/m1A9)-methyltransferase; tRNA(m1G9/m1A9)MTase; TK0422p (gene name); tRNA m1A9-methyltransferase; tRNA m1A9 Mtase. Cat No: EXWM-1820. | |
| tyramine N-methyltransferase | Has some activity on phenylethylamine analogues. Group: Enzymes. Synonyms: DIB O-methyltransferase (3,5-diiodo-4-hydroxy-benzoic acid); S-adenosyl-methionine:tyramine N-methyltransferase; tyramine methylpherase. Enzyme Commission Number: EC 2.1.1.27. CAS No. 37256-96-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1875; tyramine N-methyltransferase; EC 2.1.1.27; 37256-96-5; DIB O-methyltransferase (3,5-diiodo-4-hydroxy-benzoic acid); S-adenosyl-methionine:tyramine N-methyltransferase; tyramine methylpherase. Cat No: EXWM-1875. | |
| WDR5-0103 | WDR5-0103 is a small molecule that binds a peptide-binding pocket on WDR5 with Kd of 450 nM. It inhibits MLL catalytic activity with an IC50 value of 39±10 μM in vitro. It is a WD40-repeat antagonist that binds to WDR55 central cavity. It inhibits MLL1 histone methyltransferase activity in vitro through disruption of the interaction of MLL with WDR5. It is an essential componet of the human trithorax-like famliy of SET1 methyltransferase complexes that carry out trimethylation of histone 3 Lys4. Uses: Wdr5-0103 inhibits mll1 histone methyltransferase activity. it is an essential componet of the human trithorax-like famliy of set1 methyltransferase complexes that carry out trimethylation of histone 3 lys4. Synonyms: 3-[(3-Methoxybenzoyl)aMino]-4-(4-Methyl-1-piperazinyl)benzoic Acid Methyl Ester;Methyl 3-(3-methoxybenzamido)-4-(4-methylpiperazin-1-yl)benzoate;WDR5-0103; WDR 5-0103; WDR-5-0103; WDR50103; WDR-50103; WDR 50103; WD-Repeat Protein 5-0103. Grades: >98 %. CAS No. 890190-22-4. Molecular formula: C21H25N3O4. Mole weight: 383.44. | |
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