Acid Methyltransferase Suppliers USA
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Product | Description | |
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2-(Benzoylamino)-1-(3-phenylpropyl)-1H-benzimidazole-5-carboxylic Acid Quick inquiry Where to buy Suppliers range | 2-(Benzoylamino)-1-(3-phenylpropyl)-1H-benzimidazole-5-carboxylic Acid is a small molecule that has been reported as a novel histone methyltransferase inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1374601-41-8. Pack Sizes: 1mg, 5mg. Molecular Formula: C24H21N3O3, Molecular Weight: 399.44. US Biological Life Sciences. | Worldwide |
2-[ (Benzoylimino) (methylthio) methyl]hydrazide Benzoic Acid Quick inquiry Where to buy Suppliers range | 2-[ (Benzoylimino) (methylthio) methyl]hydrazide Benzoic Acid is an intermediate in synthesizing 1- β-D-Ribofuranosyl-3-aminocarbonyl Guandinine (R415500), which is an impurity of 5-Azacytidine (A796000). 5-Azacytidine is a potent growth inhibitor and cytotoxic agent. 5-Azacytidine acts as a demethylating agent by inhibiting DNA methyltransferase. Group: Biochemicals. Grades: Highly Purified. CAS No. 74074-45-6. Pack Sizes: 25g, 50g. Molecular Formula: C16H15N3O2S. US Biological Life Sciences. | Worldwide |
2'-O-Methyl-5-methyluridine 5'-triphosphate Quick inquiry Where to buy Suppliers range | 2'-O-Methyl-5-methyluridine 5'-triphosphate is a pivotal element for studying the captivating realm of RNA modifications. Profoundly influencing diverse cellular processes, this exquisite modified nucleotide assuming a paramount role in unraveling the enigmatic function of methylated RNA. As a versatile substrate for RNA-modifying enzymes, it unleashes unprecedented opportunities to scrutinize mesmeric methyltransferase activities and decode the multifaceted impact of this modification on the intricate structure and myriad functions of RNA. Synonyms: (((2R,3R,4R,5R)-3-Hydroxy-4-methoxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl)triphosphoric acid. CAS No. 444789-41-7. Molecular formula: C11H19N2O15P3. Mole weight: 512.19. | |
3-O-Methyl-L-DOPA-d3 Methyl Ester Quick inquiry Where to buy Suppliers range | Protected labeled 3-O-Methyl-L-DOPA. 3-O-Methyl-L-DOPA is the major metabolite of L-DOPA via catechol O-methyltransferase (COMT). 3-Methoxy-L-tyrosine is neither a substrate for nor an inhibitor of L-amino acid decarboxylase activity. Inhibition of COMT enhances the anti-Parkinson activity of L-DOPA. Group: Biochemicals. Alternative Names: 3-Methoxy-d3-L-tyrosine Methyl Ester. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
3-O-Methyl-L-DOPA-d3 Monohydrate Quick inquiry Where to buy Suppliers range | Labeled 3-O-Methyl-L-DOPA. 3-O-Methyl-L-DOPA is the major metabolite of L-DOPA via catechol O-methyltransferase (COMT). 3-Methoxy-L-tyrosine is neither a substrate for nor an inhibitor of L-amino acid decarboxylase activity. Inhibition of COMT enhances the anti-Parkinson activity of L-DOPA. Group: Biochemicals. Alternative Names: 3-(Methoxy-d3)-L-tyrosine Monohydrate; 3-(Methoxy-d3)-4-hydroxyphenylalanine Monohydrate; 3-(Methoxy-d3)-DOPA Monohydrate; 3-(Methoxy-d3)-L-tyrosine Monohydrate; 3-O-(Methyl-d3)dopa Monohydrate; L-3-(Methoxy-d3)-4-hydroxy-phenylalanine Monohydrate; L-3-O-(Methyl-d3)-DOPA Monohydrate; L-4-Hydroxy-3-(methoxy-d3)phenylalanine Monohydrate. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
3-O-Methyl-L-DOPA Methyl Ester Quick inquiry Where to buy Suppliers range | Protected 3-O-Methyl-L-DOPA. 3-O-Methyl-L-DOPA is the major metabolite of L-DOPA via catechol O-methyltransferase (COMT). 3-Methoxy-L-tyrosine is neither a substrate for nor an inhibitor of L-amino acid decarboxylase activity. Inhibition of COMT enhances the anti-Parkinson activity of L-DOPA. Group: Biochemicals. Alternative Names: 3-Methoxy-L-tyrosine Methyl Ester. Grades: Highly Purified. CAS No. 78148-37-5. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
3-O-Methyl-L-DOPA Monohydrate Quick inquiry Where to buy Suppliers range | 3-O-Methyl-L-DOPA is the major metabolite of L-DOPA via catechol O-methyltransferase (COMT). 3-Methoxy-L-tyrosine is neither a substrate for nor an inhibitor of L-amino acid decarboxylase activity. Inhibition of COMT enhances the anti-Parkinson activity of L-DOPA. Group: Biochemicals. Alternative Names: 3-Methoxy-L-tyrosine Monohydrate; 3-Methoxy-4-hydroxyphenylalanine Monohydrate; 3-Methoxy-DOPA Monohydrate; 3-Methoxy-L-tyrosine Monohydrate; 3-O-Methyldopa Monohydrate; L-3-Methoxy-4-hydroxyphenylalanine Monohydrate; L-3-O-Methyl-DOPA Monohydrate; L-4-Hydroxy-3-methoxyphenylalanine Monohydrate. Grades: Highly Purified. CAS No. 200630-46-2. Pack Sizes: 10mg, 25mg, 50mg. US Biological Life Sciences. | Worldwide |
5-(Acetylamino)-2-hydroxybenzoic acid Quick inquiry Where to buy Suppliers range | N-Acetyl Mesalazine is a metabolite of Mesalazine. It is a Salicylic Acid derivative. It is an inhibitor of recombinant human thiopurine methyltransferase (hTPMT). Synonyms: 5-acetamido-2-hydroxybenzoic acid. Grades: > 95 %. CAS No. 51-59-2. Molecular formula: C9H9NO4. Mole weight: 195.17. | |
5-Methyl-dCTP Quick inquiry Where to buy Suppliers range | 5-Methyl-dCTP, a paramount component within the biomedical industry, is deeply engrossed in DNA synthesis. During cell division and replication, it becomes embedded into DNA and is implemented by DNA methyltransferases to methylate CpG islands. Its potential for detection and quantification of DNA methylation in diverse diseases, such as cancer and neurodegenerative disorders, makes it a popular choice. Synonyms: 5-Methyl-2'-deoxycytidine-5'-Triphosphate; m5-dCTP; 5-m-dCTP; 5m-dCTP; 5-methyldeoxycytidine triphosphate. Grades: ≥ 95% by HPLC. CAS No. 22003-12-9. Molecular formula: C10H18N3O13P3 (free acid). Mole weight: 481.18 (free acid). | |
7-Methylguanosine 5'-triphosphate sodium salt Quick inquiry Where to buy Suppliers range | 7-Methylguanosine 5'-triphosphate sodium salt, a highly indispensable reagent in the field of biomedicine, finds extensive utilization across diverse applications. Functioning as a potent guanosine triphosphate (GTP) analogue, it assumes a pivotal role in the processes of mRNA capping, RNA processing, and RNA splicing. Its auxiliary role involves facilitating the exploration of RNA-protein interactions while also serving as a substrate for RNA methyltransferases. Molecular formula: C11H18N5O14P3·xNa. Mole weight: 537.21 (free acid). | |
AMI-1 Quick inquiry Where to buy Suppliers range | AMI-1 is a cell-permeable inhibitor which inhibits protein arginine N-methyltransferase (PRMT) activity with IC50 of 8.81 μM for PRMT1 and IC50 of 3.04 μM for Hmt1p in vitro. MI-1 does not compete for the AdoMet (S-adenosyl-L-methionine; SAM) binding site and exhibits minimal effects on both SET (Sub39H1, Suv39H2, SET7) and non-SET (DOT1) lysine N-methyltransferases. Furthermore, AMI-1 prevents in vivo arginine methylation of cellular proteins and can modulate nuclear receptor-regulated transcription from estrogen and androgen response elements, thus operating as a brake on certain hormone actions. Synonyms: 7,7'-(Carbonyldiimino)bis[4-hydroxy-2-naphthalenesulfonic acid] disodium salt; 5,5'-Dihydroxy-2,2'-dinaphthylcarbamide-7,7'-disulfonic acid disodium salt; 6,6'-Ureylenebis(1-naphthol-3-sulfonic acid) disodium salt; 7,7'-Ureylenebis(4-hydroxy-2-naphthalenesulfonic acid) disodium salt; Carbonyl J disodium salt; I Acid Urea disodium salt; N,N'-Bis(5-hydroxy-7-sulfo-2-naphthyl)urea disodium salt; N,N'-Bis(7-sulfo-5-hydroxy-2-naphthyl)urea disodium salt; N,N'-Bis[1-hydroxy-3-sulfonaphthyl(6)]urea disodium salt; N,N'-Bis[1-oxy-3-sulfonaphthyl(6)]urea disodium salt; AMI-1 sodium salt; AMI 1; AMI1; J Acid Urea disodium salt. Grades: ≥98%. CAS No. 20324-87-2. Molecular formula: C21H14N2Na2O9S2. Mole weight: 548.45. | |
Decitabine Impurity 3 Quick inquiry Where to buy Suppliers range | 2-Deoxy-D-erythro-pentofuranose 3,5-di-p-toluate is an impurity of Decitabine, a DNA hypomethylating agent that is used to treat various forms of cancer, such as myelogeneous leukemia and metastatic lung cancerBy inhibiting DNA methyltransferase, Decitabine silences the tumour suppressor genes and, consequently, "normalizing" gene expression in cancerous cells. Synonyms: rac-2-Deoxy-D-erythro-pentofuranose 3,5-Di-p-toluate; p-Toluic Acid 3,5-Diester with 2-Deoxy-D-erythro-pentofuranose. Grades: > 95%. CAS No. 17117-72-5. Molecular formula: C21H22O6. Mole weight: 370.4. | |
EDA-m7GDP - 5-FAM Quick inquiry Where to buy Suppliers range | EDA-m7GDP is a small molecule used in the biomedicine industry for the study of RNA processing and modification. It serves as a substrate analog for RNA cap methyltransferase and is used to investigate the role of the cap structure and its modification in RNA processing. EDA-m7GDP is also used in the development of potential antiviral drugs as it inhibits viral RNA cap formation. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with ATTO 5FAM, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C35H33N7O18P2(free acid). Mole weight: 901.63 (free acid). | |
EDA-m7GDP - ATTO-Rho14 Quick inquiry Where to buy Suppliers range | EDA-m7GDP - ATTO-Rho14 is a specialized biomedical product used in the study of RNA capping enzymes. Specifically, it is used as a fluorescent substrate for monitoring the activity of RNA cap guanine-N7 methyltransferase (RNMT) and other related enzymes. This product can potentially aid in the development of new drugs targeting RNA capping enzymes and diseases related to their dysfunction. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with ATTO Rho14, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C55H64Cl4N10O15P2(free acid). Mole weight: 1306.28 (free acid). | |
EDA-m7GDP - Texas Red Quick inquiry Where to buy Suppliers range | EDA-m7GDP - Texas Red is a fluorescent probe widely used in biomedicine to study RNA cap structures and reveal functional characteristics of RNA methyltransferase activity. It can be used to detect methylated guanine nucleotides in cells and tissues, aiding the development of new therapies for various viral diseases. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with Texas Red, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C51H62N10O19P2S2-(free acid). Mole weight: 1245.17 (free acid). | |
EDA-m7GTP - ATTO-MB2 Quick inquiry Where to buy Suppliers range | EDA-m7GTP - ATTO-MB2 is a fluorescent substrate used for studying RNA capping enzymes. It is structurally similar to m7GTP, a cap structure found at the 5' end of eukaryotic messenger RNA (mRNA). This product can be used for fluorescence polarization assays to measure the activity of RNA capping enzymes such as RNA guanine-7 methyltransferase (RNMT). Understanding the activity of these enzymes can provide insight into diseases that rely on mRNA modification, such as cancer and viral infections. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-triphosphate, labeled with ATTO-MB2, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C33H43N10O16P3S (free acid). Mole weight: 960.74 (free acid). | |
EDA-m7GTP - DY-485XL Quick inquiry Where to buy Suppliers range | EDA-m7GTP - DY-485XL is a biomedical product used in studying RNA modifications. It acts as a substrate analog for RNA cap methyltransferases, allowing for the identification and analysis of m7G modified RNAs. This product aids in the understanding of mRNA processing, translation, and the role of m7G modifications in various diseases such as cancer and neurological disorders. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-triphosphate, labeled with DY 485XL, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C39H52N9O21P3S (free acid). Mole weight: 1107.87 (free acid). | |
EDA-m7GTP - OYSTER-656 Quick inquiry Where to buy Suppliers range | EDA-m7GTP is a modified nucleotide analog extensively used in the biomedical industry for its potential in studying RNA methylation and epitranscriptomics. It is capable of binding RNA methyltransferases and RNA-binding proteins is aiding in the investigation of methyltransferase activity and RNA modification processes. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-triphosphate, labeled with OYSTER 656, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C14H24N7O15P3- OYSTER 656 (free acid). Mole weight: 1340.31 (free acid). | |
(E,E)-Farnesyl Thioacetate Quick inquiry Where to buy Suppliers range | (E,E)-Farnesyl Thioacetate, an acetate derivative of (E,E)-Farnesyl Thiol, has inhibitory activity against human isoprenylcysteine carboxyl methyltransferase (Icmt) protein. Synonyms: Ethanethioic Acid S-[(2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrien-1-yl] Ester; Ethanethioic Acid S-[(2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrienyl] Ester; S-[(2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrien-1-yl] ethanethioate. Grades: ≥95%. CAS No. 340701-35-1. Molecular formula: C17H28OS. Mole weight: 280.47. | |
Entacapone 3-b-D-glucuronide Quick inquiry Where to buy Suppliers range | Entacapone 3-b-D-glucuronide is a metabolite of Entacapone, which is a selective and reversible inhibitor of the enzyme catechol-O-methyltransferase (COMT) used in combination with other medications for the treatment of Parkinson's disease. Synonyms: β-D-Glucopyranosiduronic acid, 5-[(1E)-2-cyano-3-(diethylamino)-3-oxo-1-propen-1-yl]-2-hydroxy-3-nitrophenyl; 5-[(1E)-2-Cyano-3-(diethylamino)-3-oxo-1-propen-1-yl]-2-hydroxy-3-nitrophenyl β-D-glucopyranosiduronic acid; β-D-Glucopyranosiduronic acid, 5-[(1E)-2-cyano-3-(diethylamino)-3-oxo-1-propenyl]-2-hydroxy-3-nitrophenyl; β-D-Glucopyranosiduronic acid, 5-[2-cyano-3-(diethylamino)-3-oxo-1-propenyl]-2-hydroxy-3-nitrophenyl, (E)-; Entacapone 3-β-D-glucuronide. Grades: ≥95%. CAS No. 158069-75-1. Molecular formula: C20H23N3O11. Mole weight: 481.41. | |
EPZ011989 trifluoroacetate Quick inquiry Where to buy Suppliers range | EPZ011989 trifluoroacetate is the trifluoroacetate salt form of EPZ011989. EPZ011989 is a potent and orally bioavailable inhibitor that specifically targets the protein methyltransferase Enhancer of Zeste Homolog 2 (EZH2), with significant tumor growth in. Synonyms: EPZ011989 TFA salt; EPZ011989 TFA; EPZ 011989 TFA; EPZ-011989 TFA; N-[ (4, 6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-3-[ethyl-[4-[2-methoxyethyl (methyl)amino]cyclohexyl]amino]-2-methyl-5- (3-morpholin-4-ylprop-1-ynyl)benzamide; 2, 2, 2-trifluoroacetic acidEPZ011989 (trifluoroacetate). CAS No. 1598383-41-5. Molecular formula: C37H52F3N5O6. Mole weight: 719.83. | |
Homovanillic Acid Sulfate Sodium Salt Quick inquiry Where to buy Suppliers range | A metabolite of Dihydroxyphenylacetic Acid (DOPAC) by catechol O-methyltransferase. Group: Biochemicals. Alternative Names: 3-Methoxy-4-(sulfooxy)-benzeneacetic Acid Disodium Salt. Grades: Highly Purified. CAS No. 38339-06-9. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
Homovanillic Acid Sulfate Sodium Salt-d3 Quick inquiry Where to buy Suppliers range | A labeled metabolite of Dihydroxyphenylacetic Acid (DOPAC) by catechol O-methyltransferase. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Methotrexate EP Impurity L Quick inquiry Where to buy Suppliers range | An impurity of Methotrexate, an antimetabolite and immunosuppressant used in chemotherapy and auto-immune diseases. This impurity also acts as an inhibitor of human DNA methyltransferase. Synonyms: N-(4-(Methylamino)benzoyl)-L-glutamic acid; N-(p-(Methylamino)benzoyl)glutamic acid; (p-Methylaminobenzoyl)-L-glutamic Acid; N-[p-(Methylamino)benzoyl]-L-glutamic acid; NSC 138419. Grades: > 95%. CAS No. 52980-68-4. Molecular formula: C13H16N2O5. Mole weight: 280.28. | |
N6-Methyladenosine-5'-triphosphate lithium salt Quick inquiry Where to buy Suppliers range | N6-Methyladenosine-5'-triphosphate lithium salt is an exceptionally robust stimulant of methyltransferases, standing as a pivotal constituent employed for the scrutiny of RNA modifications. Synonyms: 6-Me-ATP. Grades: ≥ 95%. Molecular formula: C11H18N5O13P3·xLi. Mole weight: 521.21 (free acid). | |
N-Acetyl-5-aminosalicylic Acid (5-Acetylamino-2-hydroxybenzoic Acid. 5-Acetamidosalicylic Acid. N-Acetylmesalamine) Quick inquiry Where to buy Suppliers range | A Salicylic Acid derivative. Inhibitor of recombinant human thiopurine methyltransferase (hTPMT). Group: Biochemicals. Alternative Names: 5-Acetylamino-2-hydroxybenzoic Acid5-Acetamidosalicylic AcidN-Acetylmesalamine. Grades: Highly Purified. CAS No. 51-59-2. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
N-Acetyl-5-aminosalicylic Acid-methyl-d3 Quick inquiry Where to buy Suppliers range | A labeled Salicylic Acid derivative. Inhibitor of recombinant human thiopurine methyltransferase (hTPMT). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
N-Acetyl-L-Tyrosine Quick inquiry Where to buy Suppliers range | N-acetyl-L-tyrosine is an N-acetyltyrosine in which the chiral centre has L configuration. It has a role as an EC 2.1.1.4 (acetylserotonin O-methyltransferase) inhibitor, a biomarker and a human urinary metabolite. It is a N-acyl-L-tyrosine and a N-acetyltyrosine. It is a conjugate acid of a N-acetyl-L-tyrosinate. Uses: Used for research and manufacturing. Group: Amino Acid Series. CAS No. 537-55-3. Product ID: PAP-0010. | |
N-acetyl-S-farnesyl-L-cysteine Quick inquiry Where to buy Suppliers range | N-acetyl-S-farnesyl-L-cysteine is an inhibitor of the isoprenylated protein methyltransferase. Uses: Enzyme inhibitors. Synonyms: AFC; Ac-Cys(farnesyl)-OH; (2R)-2-acetamido-3-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trienyl]sulfanylpropanoic acid. Grades: ≥98%. CAS No. 135304-07-3. Molecular formula: C20H33NO3S. Mole weight: 367.5. | |
N-acetyl-S-geranylgeranyl-L-cysteine Quick inquiry Where to buy Suppliers range | N-acetyl-S-geranylgeranyl-L-Cysteine is an inhibitor of the isoprenylated protein methyltransferase. Synonyms: AGGC; (2R)-2-acetamido-3-[(2E,6E,10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraenyl]sulfanylpropanoic acid. Grades: ≥95%. CAS No. 139332-94-8. Molecular formula: C25H41NO3S. Mole weight: 435.7. | |
RG108 Quick inquiry Where to buy Suppliers range | RG108 is a DNA methyltransferase inhibitor with IC50 value of 115 nM. RG108 can enhance reprogramming of somatic cells to induced pluripotent stem (iPS) cells. Synonyms: N-Phthalyl-L-tryptophan; RG-108; (2S)-2-(1,3-dioxoisoindol-2-yl)-3-(1H-indol-3-yl)propanoic acid. Grades: >98%. CAS No. 48208-26-0. Molecular formula: C19H14N2O4. Mole weight: 334.33. | |
S-(5'-Adenosyl)-L-methionine Chloride Dihydrochloride Quick inquiry Where to buy Suppliers range | S-(5?-Adenosyl)-L-methionine chloride dihydrochloride (SAM) facilitates the transfer of methyl groups to proteins, lipids and nucleic acids. Methionine adenosyl transferase catalyses the synthesis of SAM from methionine and adenosine triphosphate (ATP). SAM functions to regulate various cellular functions like cell division, cell death, transcription, genetic stability, oxidant/antioxidant balance and polyamine homeostasis. Therapeutically, SAM finds its application as a nutritional supplement in humans for various diseases like osteoarthritis and liver injury. SAM also regulates transsulfuration reactions by binding to the regulatory domain of key enzyme cystathionine- β-synthase (CBS).S-(5?-Adenosyl)-L-methionine chloride dihydrochloride has been used as a medium supplement for S30 cell extract. It also has been used for measuring the interaction with catechol-O-methyltransferase (COMT) by quartz crystal microbalance (QCM), surface plasmon resonance (SPR) and isothermal titration calorimetry (ITC) with supported lipid bilayers and vesicles. Group: Biochemicals. Alternative Names: 5'- [ [ (3S) -3-Amino-3-carboxypropyl] methylsulfonio] -5'-deoxyadenosine dihydrochloride; 5'-[ (L-3-Amino-3-carboxypropyl) methylsulfonio]-5'-deoxyadenosine dihydrochloride; S-Adenosylmethionine dihydrochloride; SAM chloride dihydrochloride; Active Methionine Disulfate; Ademetionine dihydrochloride; L-S-Adenosylmethionin dihydrochloride; S-Adenosyl-L-methionine dihydrochloride. Grades: Purified. CAS No. 86867-01-8. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C15H23ClN6O5S·2HCl, Molecular Weight: 507.82. US Biological Life Sciences. | Worldwide |
trans, trans Farnesylthiosalicylic Acid (FTS, (3,7,11-Trimethyldodeca-2,6,10-trienyl)-2-thiobenzoic Acid) Quick inquiry Where to buy Suppliers range | A potent prenylated protein methyltransferase (PPMTase) inhibitor. Selectively inhibits the growth of human Ha-ras-transformed Rat1 cells in vitro (EC50=7.5uM). Group: Biochemicals. Alternative Names: FTS, (3,7,11-Trimethyldodeca-2,6,10-trienyl)-2-thiobenzoic Acid. Grades: Highly Purified. CAS No. 162520-00-5. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
WDR5-0103 Quick inquiry Where to buy Suppliers range | WDR5-0103 is a small molecule that binds a peptide-binding pocket on WDR5 with Kd of 450 nM. It inhibits MLL catalytic activity with an IC50 value of 39±10 μM in vitro. It is a WD40-repeat antagonist that binds to WDR55 central cavity. It inhibits MLL1 histone methyltransferase activity in vitro through disruption of the interaction of MLL with WDR5. It is an essential componet of the human trithorax-like famliy of SET1 methyltransferase complexes that carry out trimethylation of histone 3 Lys4. Uses: Wdr5-0103 inhibits mll1 histone methyltransferase activity. it is an essential componet of the human trithorax-like famliy of set1 methyltransferase complexes that carry out trimethylation of histone 3 lys4. Synonyms: 3-[(3-Methoxybenzoyl)aMino]-4-(4-Methyl-1-piperazinyl)benzoic Acid Methyl Ester;Methyl 3-(3-methoxybenzamido)-4-(4-methylpiperazin-1-yl)benzoate;WDR5-0103; WDR 5-0103; WDR-5-0103; WDR50103; WDR-50103; WDR 50103; WD-Repeat Protein 5-0103. Grades: >98 %. CAS No. 890190-22-4. Molecular formula: C21H25N3O4. Mole weight: 383.44. |