Acid Phosphatase Suppliers USA
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Product | Description | |
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Prostatic acid phosphatase (112-120) Quick inquiry Where to buy Suppliers range | Prostatic acid phosphatase. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-282. | |
Prostatic acid phosphatase (18-26) Quick inquiry Where to buy Suppliers range | Prostatic acid phosphatase. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-281. | |
Prostatic acid phosphatase (299-307) Quick inquiry Where to buy Suppliers range | Prostatic acid phosphatase. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-283. | |
LYP Inhibitor II, LTV-1 (Lymphoid Tyrosine Phosphatase Inhibitor II, LTV-1, (E) -3- ( (4- ( (4, 6-Dioxo-2-thioxo-1-o-tolyltetra hydropyrimidin-5 (6H) -ylide ne ) methyl ) phenoxy) methyl ) benzoic Acid) Quick inquiry Where to buy Suppliers range | A cell-permeable thiobarbituryl-benzoate compound that acts as a highly potent and reversible inhibitor of lymphoid tyrosine phosphatase (LYP) (IC50=508nM) and thereby enhances TCR signaling in intact cells. Exhibits competitive to mixed mode of inhibition (Ki=384nM). Also shown to inhibit the mutant, disease associated LYP-Trp620 activity. Binds to the phosphate-binding loop and mimicks the phosphotyrosine moiety of substrates. Displays acceptable selectivity over a wide range of protein phosphatases (TCPTP, PTP1B, PEP (mouse LYP), SHP1, CD45 and PTP-PEST: IC50=1.52, 1.59, 7.56, 23.2, 30.1, and 100uM, respectively). Does not exhibit any toxicity at pharmacological doses when tested in primary human cell lines. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
1-Naphthyl Phosphate Monosodium Salt Monohydrate, 99% Quick inquiry Where to buy Suppliers range | A non-specific phosphatase inhibitor. Inhibits acid, alkaline and protein phosphatases. Group: Biochemicals. Alternative Names: α-Naphthyl phosphate monosodium salt monohydrate;?α-Naphthyl phosphoric acid monosodium salt monohydrate. Grades: Reagent Grade. CAS No. 81012-89-7. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
1-Naphthyl phosphate potassium salt Quick inquiry Where to buy Suppliers range | 1-Naphthyl phosphate potassium salt is a non-specific phosphatase inhibitor which acts on acid, alkaline, and protein phosphatases. Synonyms: α-Naphthyl acid phosphate monopotassium salt; napthalen-1-yl 3,5-dinitrobenzoate; naphthalen-1-yl dihydrogen phosphate potassium. Grades: ≥95%. CAS No. 100929-85-9. Molecular formula: C10H8O4P·K. Mole weight: 262.24. | |
(1R-trans)-Decamethrinic Acid Quick inquiry Where to buy Suppliers range | (1R-trans)-Decamethrinic Acid is an intermediate in the synthesis of trans-Deltamethrin which is trans isomer of Deltamethrin (D230700), a synthetic pyrethroid insecticide, which acts as a potent inhibitor of calcineurin (protein phosphatase 2B) and has an IC50 of about 100pM. Group: Biochemicals. Grades: Highly Purified. CAS No. 63538-10-3. Pack Sizes: 2.5g, 5g. Molecular Formula: C8H10Br2O2. US Biological Life Sciences. | Worldwide |
2-(1-Piperidino)aniline Quick inquiry Where to buy Suppliers range | 2-(1-Piperidino)aniline is used to prepare oxalylarylaminobenzoic acids as inhibitors of protein tyrosine phosphatase 1B. It is also used to synthesize benzimidazole derivatives as AMP-activated protein kinase activators. Group: Biochemicals. Grades: Highly Purified. CAS No. 39643-31-7. Pack Sizes: 100mg, 250mg. Molecular Formula: C11H16N2. US Biological Life Sciences. | Worldwide |
2,5-Difluorobenzoic acid Quick inquiry Where to buy Suppliers range | 2,5-Difluorobenzoic Acid acts as a reagent in the synthesis of rutaecarpine and analogs used for the removal of caffeine from the body. Prepparation of quinolone carboxylic acids as cell-permeable inhibitors of protein tyrosine phosphatase (Erratum). Preparation, molecular docking, and bioactivity of α-ketoamides as cathepsin S inhibitors with potential applications against tumor invasion and angiogenesis. Also used as new passive water tracers for oil field applications. Synonyms: NSC 190310; 5-Difluorobenzoic acid; 2,5-difluorobenzoate. Grades: ≥95%. CAS No. 2991-28-8. Molecular formula: C7H4F2O2. Mole weight: 158.10. | |
2,5-Difluorobenzoic Acid Quick inquiry Where to buy Suppliers range | 2,5-Difluorobenzoic Acid acts as a reagent in the synthesis of rutaecarpine and analogs used for the removal of caffeine from the body. Prepparation of quinolone carboxylic acids as cell-permeable inhibitors of protein tyrosine phosphatase (Erratum). Preparation, molecular docking, and bioactivity of α-ketoamides as cathepsin S inhibitors with potential applications against tumor invasion and angiogenesis. Also used as new passive water tracers for oil field applications. Group: Biochemicals. Grades: Highly Purified. CAS No. 2991-28-8. Pack Sizes: 1g, 5g. Molecular Formula: C7H4F2O2. US Biological Life Sciences. | Worldwide |
2-Chloro-4-nitrophenyl phosphate Quick inquiry Where to buy Suppliers range | 2-Chloro-4-nitrophenyl phosphate, an indispensable compound in the field of biomedicine, possesses extraordinary capabilities in suppressing protein tyrosine phosphatases (PTPs). This fundamental trait renders it a promising avenue for therapeutic intervention against an array of ailments, encompassing malignancies and autoimmune disorders, by selectively targeting PTPs implicated in intricate signal transduction cascades. Synonyms: 2-Chloro-4-nitrophenyl dihydrogen phosphate; 14957-98-3; (2-chloro-4-nitrophenyl) dihydrogen phosphate; AGN-PC-0N3TPY; SCHEMBL1134003; DTXSID40439315; 2-Chloro-4-nitrophenyldihydrogenphosphate; (2-chloro-4-nitrophenoxy)phosphonic acid; A919724. CAS No. 14957-98-3. Molecular formula: C6H5ClNO6P. Mole weight: 253.53. | |
2-Chloro-5-iodobenzoic Acid Quick inquiry Where to buy Suppliers range | 2-Chloro-5-iodobenzoic Acid is a useful synthetic intermediate. It is used to prepare metabotropic glutamate receptor subtype-?2 (mGluR2) positive allosteric modulator (PAM). It is also used to synthesize quinolone carboxylic acids as cell-permeable inhibitors of protein tyrosine phosphatase. Group: Biochemicals. Grades: Highly Purified. CAS No. 19094-56-5. Pack Sizes: 5g, 25g. Molecular Formula: C7H4ClIO2, Molecular Weight: 282.459999999999. US Biological Life Sciences. | Worldwide |
2-(Cyanomethyl)benzoic Acid Quick inquiry Where to buy Suppliers range | 2-(Cyanomethyl)benzoic Acid react with substituted to synthesize 1-Aryl-2H-isoquinolin-3-ones. Also, it is used in the synthesis of 6- (3-Aminophenyl) -3- (phenylamino) isoquinolin-1 (2H) -one which is an inhibitor of the dual-specificity phosphatase Cdc25B. Group: Biochemicals. Grades: Highly Purified. CAS No. 6627-91-4. Pack Sizes: 250mg, 500mg. Molecular Formula: C9H7NO2, Molecular Weight: 161.16. US Biological Life Sciences. | Worldwide |
2'-Deoxycytidine 3'-monophosphate ammonium salt Quick inquiry Where to buy Suppliers range | 2'-Deoxycytidine 3'-monophosphate ammonium salt is a nucleotide-like compound that is extensively employed in scientific research, especially in the disciplines of DNA sequencing and synthesis. Furthermore, it serves as an essential ingredient for various phosphatases and kinases. With its unique properties, it has the potential to combat a variety of viral infections and cancers, thus opening up new avenues for therapeutic interventions. Synonyms: 2'-Deoxycytidine-3'-monophosphate tetraammonium salt; (2R,3S,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-2-(hydroxymethyl)tetrahydrofuran-3-yl dihydrogen phosphate, ammonia salt; 2'-Deoxy-3'-cytidylic acid ammoniate (1:1); 2'-Desoxycytidine 3'-(dihydrogen phosphate) ammonium salt (1:1). Grades: ≥97% by HPLC. CAS No. 102783-50-6. Molecular formula: C9H17N4O7P. Mole weight: 324.23. | |
(2E)-3-Cyclobutyl-2-propenoic Acid Quick inquiry Where to buy Suppliers range | ((2E)-3-Cyclobutyl-2-propenoic Acid is a used in the preparation of (S)-2,7-substituted-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids as peroxisome proliferator-activated receptor α/γ dual agonists with protein-tyrosine phosphatase 1B inhibitory activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 1355450-70-2. Pack Sizes: 250mg, 500mg. Molecular Formula: C7H10O2, Molecular Weight: 126.15. US Biological Life Sciences. | Worldwide |
2-hydroxy-4-[[6-[5-[ (4-methylphenyl) methylene]-4-oxo-2-thioxo-3-thiazolidinyl]-1-oxohexyl]amino]benzoic Acid Quick inquiry Where to buy Suppliers range | 2-hydroxy-4-[[6-[5-[ (4-methylphenyl) methylene]-4-oxo-2-thioxo-3-thiazolidinyl]-1-oxohexyl]amino]benzoic Acid, is a Dual-specificity phosphatase 26 (DUSP26) inhibitor with an IC50 of 11.62 μM. Group: Biochemicals. Grades: Highly Purified. CAS No. 613225-56-2. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C24H24N2O5S2, Molecular Weight: 484.59. US Biological Life Sciences. | Worldwide |
3,5-Dihydroxynapthalene-2-carboxylic Acid Quick inquiry Where to buy Suppliers range | 3,5-Dihydroxynapthalene-2-carboxylic Acid is used as a negative or positive NMDA receptor inhibitor, via allosteric control. NMDA receptors regulate CHN (central nervous system) functions. Also used as a protein tyrosine phosphatase inhibitor due to the benzofuran-like moiety in the substructure. Group: Biochemicals. Alternative Names: UBP551. Grades: Highly Purified. CAS No. 89-35-0. Pack Sizes: 1g, 10g, 50g. Molecular Formula: C11H8O4, Molecular Weight: 204.18. US Biological Life Sciences. | Worldwide |
3-Amino-2-methoxycarbonyl thiophene Quick inquiry Where to buy Suppliers range | 3-Amino-2-methoxycarbonyl thiophene is a useful synthetic intermediate. It can be used to synthesize (amino)thienopyridine derivatives as possible inhibitors of VEGFR-2 kinase and EGFR kinase. It can also be used to prepare (carboxyheteroaryl amino) oxalic acids as inhibitors of protein-tyrosine phosphatase 1B. Group: Biochemicals. Grades: Highly Purified. CAS No. 22288-78-4. Pack Sizes: 5g, 25g. Molecular Formula: C6H7NO2S, Molecular Weight: 157.19. US Biological Life Sciences. | Worldwide |
4-Methylumbelliferyl pyrophosphate diester disodium salt Quick inquiry Where to buy Suppliers range | 4-Methylumbelliferyl pyrophosphate diester disodium salt is a substance widely acknowledged in the field of biomedical research, proving to be an exceptionally intricate and multifaceted substrate. It plays a key role in enzymatic assays aimed at gauging the potency of alkaline phosphatase. Synonyms: Bis(4-methylumbelliferyl)pyrophosphoric acid disodium salt. CAS No. 84282-11-1. Molecular formula: C20H14O11P2.2Na. Mole weight: 538.25. | |
4-Nitrophenyl phosphate Quick inquiry Where to buy Suppliers range | 4-Nitrophenyl phosphate is a crucial recompound utilized in the biomedical industry for the detection of alkaline phosphatase activity. It undergoes enzymatic hydrolysis by alkaline phosphatase, resulting in the release of a yellow compound that can be measured spectrophotometrically. This recompound finds applications in the research of various diseases, including liver diseases, bone disorders is and genetic abnormalities. Synonyms: PHOSPHORIC ACID MONO-(4-NITRO-PHENYL) ESTER. CAS No. 330-13-2. Molecular formula: C6H6NO6P. Mole weight: 219.09. | |
5-Carboxypentyl triphenylphosphonium bromide Quick inquiry Where to buy Suppliers range | 5-Carboxypentyl triphenylphosphonium bromide. Uses: (5-Carboxypentyl)(triphenyl)phosphonium bromide is used in medicine and as pharmaceutical intermediate. It is also employed as catalyst. Reactant for: Preparation of inhibitor of protein tyrosine phosphatase 1B for treatment of diabetes and obesity. Synthesis of folate receptor-specific glycinamide ribonucleotide formyltransferase inhibitors with antitumor activity. Preparation of peptide nucleic acids (PNA) with high specific activity. Synthesis of roseophilin via Wittig/aldol methodology. Group: Organic Phosphine Compounds. Alternative Names: AN-41369; AC1MCV6O; (5-Carboxyamyl)triphenylphosphonium Bromide; (5-Carboxypentyl)triphenylphosphonium bromide; DTXSID80381364; MFCD00055556 (97%); K-9387; 5-carboxypentyl(triphenyl)phosphonium bromide; 5-carboxypentyl-triphenylphosphonium bromide; RP07141. CAS No. 50889-29-7. Molecular formula: C24H26BrO2P. Mole weight: 457.348g/mol. IUPAC Name: 5-carboxypentyl(triphenyl)phosphanium; bromide. Rotatable Bond Count: 9. Exact Mass: 456.085g/mol. SMILES: C1=CC=C (C=C1)[P+] (CCCCCC (=O)O) (C2=CC=CC=C2)C3=CC=CC=C3. [Br-]. InChI: InChI=1S/C24H25O2P.BrH/c25-24(26)19-11-4-12-20-27(21-13-5-1-6-14-21,22-15-7-2-8-16-22)23-17-9-3-10-18-23;/h1-3,5-10,13-18H,4,11-12,19-20H2;1H. InChIKey: JUWYRPZTZSWLCY-UHFFFAOYSA-N. H-Bond Donor: 1. H-Bond Acceptor: 3. Monoisotopic Mass: 456.085g/mol. | |
6-Chloro-3-indolyl phosphate p-toluidine salt Quick inquiry Where to buy Suppliers range | 6-Chloro-3-indolyl phosphate p-toluidine salt is an indispensable recompound in the biomedical sphere, holding applications encompasses the colorimetric appraisal of alkaline phosphatase activity across diverse domains. Essential in the study of alkaline phosphatase-related ailments, this compound facilitates meticulous identification and comprehensive analysis. Synonyms: 6-Chloro-3-indolyl phosphate p-toluidine salt; Salmon phosphate; 154201-84-0; p-Toluidine 6-chloro-1H-indol-3-yl phosphate; 6-Chloro-3-indoxyl phosphate, p-toluidine salt; (6-chloro-1H-indol-3-yl) dihydrogen phosphate; 4-methylaniline; (6-chloro-1H-indol-3-yl) hydrogen phosphate; (4-methylphenyl)azanium; 6-Chloro-3-indolyl phosphate, p-toluidine salt; 6-Chloro-3-indolyl-phosphate p-toluidine salt; SCHEMBL9299192; DTXSID10165558; Salmon-phosphate p-toluidine salt; AMY41655; MFCD00216690; AKOS015911346; FD10021; CS-0324256; C-5100; A906756; 4-methylaniline; [(6-chloro-1H-indol-3-yl)oxy]phosphonic acid; 6-Chloro-3-indolyl phosphate p-toluidine salt, >=98.0% (HPLC); 1H-Indol-3-ol, 6-chloro-, dihydrogen phosphate (ester), compd. with 4-methylbenzenamine (1:1) (9CI). CAS No. 159954-33-3. Molecular formula: C8H6ClNO4P.C7H10N. Mole weight: 354.73. | |
8-[(4-Amino)butyl]-amino-ATP - MANT Quick inquiry Where to buy Suppliers range | 8-[(4-Amino)butyl]-amino-ATP-MANT, a fluorescently labeled ATP analogue utilized in biomedical research, provides a means for measuring the kinetics of kinase or phosphatase activity on ATP hydrolysis. With varying applications, it has demonstrated significance in the study of ATP-binding cassette transporters linked to cystic fibrosis and drug resistance. Overall, this product serves as an invaluable tool in the advancement of scientific inquiry. Synonyms: (MABA-ATP); 8-[(4-Amino)butyl]-amino-adenosine-5'-triphosphate, labeled with MANT, Triethylammonium salt. Grades: ≥ 95% by HPLC. CAS No. 185155-33-3. Molecular formula: C22H33N8O14P3 (free acid). Mole weight: 726.47 (free acid). | |
Adenosine-5'-(4-fluorosulfonylphenylphosphate) Quick inquiry Where to buy Suppliers range | Adenosine-5'-(4-fluorosulfonylphenylphosphate) is a crucial compound in the biomedical industry. It is extensively utilized for studying the enzymatic activity of protein tyrosine phosphatases (PTPs). Additionally, this product serves as a valuable tool to investigate diseases like cancer, autoimmune disorders, and diabetes where PTP dysregulation plays a role. Its availability ensures accurate analysis and facilitates advancements in biomedicine research. Synonyms: [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl (4-fluorosulfonylphenyl) hydrogen phosphate;5'-Adenylic acid, mono(4-(fluorosulfonyl)phenyl) ester; 9- (5-O-{[4- (Fluorosulfonyl)phenoxy] (hydroxy)phosphoryl}pentofuranosyl)-9H-purin-6-amine. CAS No. 60397-89-9. Molecular formula: C16H17FN5O9PS. Mole weight: 505.37. | |
A-kinase anchor protein 9 (1398-1407) Quick inquiry Where to buy Suppliers range | A-kinase anchor protein 9 (1398-1407) is amino acids 1398 to 1407 fragment of A-kinase anchor protein 9. AKAP-9 is a scaffolding protein that assembles several protein kinases and phosphatases on the centrosome and Golgi apparatus. Synonyms: AKAP-9 (1398-1407). | |
Alendronate sodium (Sodium [4-amino-1-hydroxy-1-(hydroxy-oxido-phosphoryl)- butyl]phosphonic acid, trihydrate, MK-217, Fosamax) Quick inquiry Where to buy Suppliers range | Alendronate sodium is a bisphosphonate that acts as a specific inhibitor of osteoclast-mediated bone resorption. It inhibits bone resorption in vitro with an IC?? value of 2nm. Also acts as a farnesyl diphosphate synthase inhibitor (IC?? =460nm) and CD45 protein tyrosine phosphatase inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 121268-17-5. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
Alexidine dihydrochloride Quick inquiry Where to buy Suppliers range | Alexidine dihydrochloride is a potent and selective protein tyrosine phosphatase localized to the mitochondrion 1(PTPMT1) inhibitor with IC50 value of 1.08 μM in vitro. It induces apoptosis in cancer cell lines with ED50 value of 1.8-2.6 μM. It is an alkyl bis(biguanide) antiseptic and has been used in mouthwashes to eliminate plaque forming microorganisms. It binds to lipopolysaccharide and lipoteichoic acid, and inhibits fungal phospholipase B with IC50 value of 250 nM. It stimulates increased insulin secretion by isolated rat pancreatic islets and displays antitcancer properties in FaDu cells. It has antibacterial, antiplaque properties against streptococcus mutans, actinomyces naesludii and actinomyces ciscosus. Synonyms: 2,4,11,13-Tetraazatetradecanediimidamide, N1,N14-bis(2-ethylhexyl)-3,12-diimino-, hydrochloride (1:2); 2,4,11,13-Tetraazatetradecanediimidamide, N,N''-bis(2-ethylhexyl)-3,12-diimino-, dihydrochloride; Biguanide, 1,1'-hexamethylenebis[5-(2-ethylhexyl)-, dihydrochloride; 1,6-Bis(2-ethylhexylbiguanido)hexane dihydrochloride; Alexidine hydrochloride; Hexamethylenebis(2-ethylhexyl)biguanide dihydrochloride. Grades: >98%. CAS No. 1715-30-6. Molecular formula: C26H58N10Cl2. Mole weight: 581.71. | |
α-casein dephosphorylation Quick inquiry Where to buy Suppliers range | Dephosphorylated casein is prepared by the action of potato acid phosphatase. It displays improved solubility and less foaming.Clusters of phosphoserine in casein chelate iron and reduce its bioavailability. Partial enzymatic digestion of casein unmasks phosphorylated residues to alkaline phosphatase, permitting dephosphorylation and increasing the bioavailability of iron.Dephosphorylated casein lacks a net negative charge and is less sensitive to calcium. It is useful in food industry. Uses: ·Nutritional supplements ·Raw material of food ·Paint, wood glue, plastic fiber ·Dentist materials ·General analytical. Group: Animal Hydrocolloids. CAS No. 9000-71-9. Molecular Weight: 2061.96 g/mol. Boiling Point: 280 °C (dec.) (lit.). Flash Point: ≥70 %. Purity: 1.26 g/cm3. Density: H2O: insoluble, forms a cloudy suspension. | |
α-Oxo-2-furanacetic Acid Quick inquiry Where to buy Suppliers range | α-Oxo-2-furanacetic Acid is an α-ketocarboxylic acid with inhibitory activity against protein tyrosine phosphatases. Group: Biochemicals. Alternative Names: 2-(2-Furyl)-2-oxoacetic acid; 2-(Furan-2-yl)-2-oxoacetic acid; 2-Furanyl(oxo)acetic acid; 2-Furylglyoxylic acid; 2-Oxo-2-(2-furanyl)acetic acid; Furoylformic acid; NSC 59069; 2-Furanglyoxylic acid. Grades: Highly Purified. CAS No. 1467-70-5. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
Alphostatin Quick inquiry Where to buy Suppliers range | BMG59-R2 is a peptide antibiotic produced by Bacillus megaterium BNG59-R2. It can inhibit the activity of alkaline phosphatase and also has anti-tumor activity. Synonyms: L-Glutamic acid, N-(N(sup 2)-(N-(N-L-isoleucyl-L-isoleucyl)-O-phosphono-L-seryl)-L-glutaminyl)-, hydrate; BMG59-R2. Grades: >98%. CAS No. 90119-88-3. Molecular formula: C25H45N6O13P. Mole weight: 668.63. | |
Antibiotic RK-682 (Antibiotic TAN 1364B, Antibiotic CI 010) Quick inquiry Where to buy Suppliers range | Antibiotic RK-682 is the calcium salt of one of a complex family of tetronic acids isolated from Streptomyces species. The formation of the salt is almost certainly an artefact of silica chromatography. RK-682 is the most extensively studied of the analogues, having been shown to inhibit protein tyrosine phosphatases and heparanase. Pharmacological studies with RK-682 demonstrated enhanced ATP-induced long-term potentiation using guinea-pig hippocampal slices. Investigation of the complex has also shown potent activity against HIV-1 protease. Group: Biochemicals. Alternative Names: Antibiotic TAN 1364B, Antibiotic CI 010. Grades: Highly Purified. CAS No. 154639-24-4(TAN1364B). Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
AS 1842856 Quick inquiry Where to buy Suppliers range | AS 1842856 is a potent and selective inhibitor of Forkhead box protein O1 transcription factor (FoxO1; IC50 = 33 nM). AS 1842856 reduces glucose production in dose manner via the inhibition of glucose-6 phosphatase and phosphoenolpyruvate carboxykinase mRNA levels in a rat hepatic cell line. AS 1842856 is promisingly to be a therapy of type 2 diabetes mellitus and obesity. Uses: Potential treatment of type 2 diabetes mellitus and obesity. Synonyms: AS1842856; AS-1842856; AS 1842856. 5-amino-7-(cyclohexylamino)-1-ethyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid. Grades: 99%. CAS No. 836620-48-5. Molecular formula: C18H22FN3O3. Mole weight: 347.38. | |
bpV(pic) potassium hydrate Quick inquiry Where to buy Suppliers range | BpV(pic) is composed of a vanadate molecule coordinated to picolinic acid (2-carboxypyridine) and potassium. It is a bisperoxovanadium (bpV) compound that inhibits several different protein tyrosine phosphatases (PTPs) with IC50 of 31 nM. It is also known to be an insulin mimetic capable of activating the insulin receptor kinase of cultured hepatoma cells and stimulating lipogenesis in adipocytes. BpV(pic) has been shown to activate the insulin receptor kinase (IRK) of cultured hepatoma cells and is also an inhibitor of G6Pase. Synonyms: Bisperoxovanadium(pic). Grades: ≥96%. CAS No. 148556-27-8. Molecular formula: C6H4NO7V·2K·2H2O. Mole weight: 367.3. | |
CALYCULIN A Quick inquiry Where to buy Suppliers range | Calyculin A is a effective inhibitor of the catalytic subunit of type-2A phosphatase as well as the type-1 phosphatase. IC50: 0.5 to 1 nM and 2 nM,respectively. It has lower IC50 value than okadaic acid which is a active blocker of phosphatase mentioned a. Uses: Calyculin a is a effective inhibitor of the catalytic subunit of type-2a phosphatase as well as the type-1 phosphatase. Synonyms: CALYCULIN A;CALYCULIN A, DISCODERMIA CALYX;calyculin A from discodermia calyx;CALYCULIN A FROM DISCODERMIA CALYX, 10 U G;N-[(3S)-[4-(1E)-3-[(2R,3R,4R,7S,8S,9R)-2-[(1S,3S,4S,5R,7E,9E,11E,13Z)-14-Cyano-3,5-dihydroxy-1-methoxy-4,6,8,9,13-pentam;L-Ribonamide. Grades: >98 %. CAS No. 101932-71-2. Molecular formula: C50H81N4O15P. Mole weight: 1009.17. | |
Cantharidic acid sodium salt Quick inquiry Where to buy Suppliers range | Cantharidic acid is an inhibitor of protein phosphatases, which is first isolated from Chinese blister beetles. Cantharidic acid is a hydrolysis product of cantharidin, it can inhibits the protein phosphatases PP1 and PP2A with IC50 values of 0.6 and 0.05 μM, respectively. Cantharidic acid is frequently used to study cellular processes that are regulated by reversible protein phosphorylation. Synonyms: Disodium cantharidin; Cantharidin disodium; 1465-77-6; Disodium cantharidate; 8OIF7X5MK8; Cantharidic Acid (sodium salt); disodium (1R,2S,3R,4S)-2,3-dimethyl-7-oxabicyclo[2.2.1]heptane-2,3-dicarboxylate; disodium; (1R,2S,3R,4S)-2,3-dimethyl-7-oxabicyclo[2.2.1]heptane-2,3-dicarboxylate; 7-Oxabicyclo(2.2.1)heptane-2,3-dicarboxylic acid, 2,3-dimethyl-, disodium salt, (exo,exo)-; UNII-8OIF7X5MK8. Grades: ≥95%. CAS No. 1465-77-6. Molecular formula: C10H12O5·2Na. Mole weight: 258.2. | |
Casein, dephosphorylated from bovine milk Quick inquiry Where to buy Suppliers range | Dephosphorylated casein is prepared by the action of potato acid phosphatase. It displays improved solubility and less foaming. Uses: ·Nutritional supplements ·Raw material of food ·Paint, wood glue, plastic fiber ·Dentist materials ·General analytical. Group: Animal Hydrocolloids. CAS No. 9000-71-9. Molecular Weight: 2061.96 g/mol. Boiling Point: 280 °C (dec.) (lit.). Flash Point: ≥70 %. Purity: 1.26 g/cm3. Density: H2O: insoluble, forms a cloudy suspension. | |
Copper Citrate Quick inquiry Where to buy Suppliers range | Copper Citrate was used to study the effects of copper on activity and kinetics of free and mineral-immobilized acid phosphatase. Group: Biochemicals. Alternative Names: 2-Hydroxy-1,2,3-propanetricarboxylic Acid Copper Salt; Citric Acid Copper Salt. Grades: Highly Purified. CAS No. 10402-15-0. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |
CSPD Quick inquiry Where to buy Suppliers range | CSPD is a chemiluminescent alkaline phosphatase substrate used for the imprinting of proteins or nucleic acids on nitrocellulose membranes. Synonyms: 3-(2'-(Spiro-5-chloroadamantane))-4-methoxy-4-(3''-phosphoryloxy)phenyl-1,2-dioxetane; 3-(4-Methoxyspiro(1,2-dioxetane-3,2'-(5'-chloro)tricyclo(3.3.1.1(3,7))decan)-4-yl)phenyl phosphate; Phenol, 3-(5'-chloro-4-methoxyspiro(1,2-dioxetane-3,2'-tricyclo(3.3.1.1(3,7))decan)-4-yl)-, dihydrogen phosphate. Grades: >96% by HPLC. CAS No. 142456-88-0. Molecular formula: C18H22ClO7P. Mole weight: 416.79. | |
CX08005 Quick inquiry Where to buy Suppliers range | CX08005 is a competitive inhibitor of PTP1B (IC50 = 0.781 μM). CX08005 binds catalytic P-loop of enzyme. It exhibits some selectivity for PTP1B over other protein tyrosine phosphatases, except TCPTP. Synonyms: 2-[[[2- (Tetradecyl) phenyl]amino]carbonyl]benzoic acid. Grades: ≥98% by HPLC. CAS No. 1256341-22-6. Molecular formula: C28H39N04. Mole weight: 453.61. | |
Cyclosporine metabolite M17 Quick inquiry Where to buy Suppliers range | Cyclosporine metabolite M17 is a metabolite of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Uses: A cyclosporine metabolite specifically inhibits growth of renal cells in culture. Synonyms: Cyclosporin AM 1; 6-[(2S,3R,4R,6E)-3,8-Dihydroxy-4-methyl-2-(methylamino)-6-octenoic acid]cyclosporin A; Cyclosporin A Metabolite M17; Cyclosporin metabolite AM1; OL-17; 1,4,7,10,13,16,19,22,25,28,31-Undecaazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone, 33-[(1R,2R,4E)-1,6-dihydroxy-2-methyl-4-hexen-1-yl]-30-ethyl-1,4,7,10,12,15,19,25,28-nonamethyl-3,21-bis(1-methylethyl)-6,9,18,24-tetrakis(2-methylpropyl)-, (3S, 6S, 9S, 12R, 15S, 18S, 21S, 24S, 30S, 33S)-. Grades: ≥90% by HPLC. CAS No. 89270-28-0. Molecular formula: C62H111N11O13. Mole weight: 1218.61. | |
Cyclosporin Impurity 2 Quick inquiry Where to buy Suppliers range | Cyclosporin Impurity 2 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: (2S,3R,4R,E)-3,8-dihydroxy-4-methyl-2-(methylamino)oct-6-enoic acid. Grades: ≥90% by HPLC. Molecular formula: C10H19NO4. Mole weight: 217.26. | |
Cyclosporin Impurity 5 Quick inquiry Where to buy Suppliers range | Cyclosporin Impurity 5 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: 10-[(2S)-2-Aminobutanoic acid]cyclosporin A; Cyclosporin A, 10-[(2S)-2-aminobutanoic acid]-; [Abu5]cyclosporin; cyclo[Abu-Sar-N(Me)Leu-Abu-N(Me)Leu-Ala-D-Ala-N(Me)Leu-N(Me)Leu-N(Me)Val-N(Me)Bmt(E)]; cyclo[(N-(((2S)-2-aminobutyryl)-sarcosyl-N-methyl-L-leucyl)-(2S)-2-aminobutyryl)-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-N-methyl-(4R)-4-[(E)-but-2-enyl]-4-methyl-L-threonyl]; (3S, 6S, 9S, 12R, 15S, 18S, 21S, 24S, 30S, 33S)-21, 30-diethyl-33-((1R, 2R, E)-1-hydroxy-2-methylhex-4-en-1-yl)-6, 9, 18, 24-tetraisobutyl-3-isopropyl-1, 4, 7, 10, 12, 15, 19, 25, 28-nonamethyl-1, 4, 7, 10, 13, 16, 19, 22, 25, 28, 31-undecaazacyclotritriacontan-2, 5, 8, 11, 14, 17, 20, 23, 26, 29, 32-undecaone. Grades: ≥95%. CAS No. 437611-17-1. Molecular formula: C61H109N11O12. Mole weight: 1188.58. | |
Cyclosporin L Related Compound 1 Quick inquiry Where to buy Suppliers range | Cyclosporin L Related Compound 1 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: (E)-(R)-2-Methyl-hex-4-enoic acid. Grades: ≥90% by HPLC. CAS No. 93553-73-2. Molecular formula: C7H12O2. Mole weight: 128.17. | |
Cyclosporin L Related Compound 3 Quick inquiry Where to buy Suppliers range | Cyclosporin L Related Compound 3 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: (E)-(2R,3S,4R)-2-Amino-3-hydroxy-4-methyl-oct-6-enoic acid; (2R,3S,4R,6E)-2-amino-3-hydroxy-4-methyl-6-octenoic acid; 2-Amino-4-[(2E)-2-buten-1-yl]-2,4,5-trideoxy-L-arabinonic acid; L-Arabinonic acid, 2-amino-4-[(2E)-2-buten-1-yl]-2,4,5-trideoxy-. Grades: ≥90% by HPLC. CAS No. 174292-85-4. Molecular formula: C9H17NO3. Mole weight: 187.24. | |
Cyclosporin V Quick inquiry Where to buy Suppliers range | Cyclosporin V is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: Cyclosporine V; Ciclosporin EP Impurity E; Cyclosporin A, 1-[(2S)-2-aminobutanoic acid]-; 1-[(2S)-2-Aminobutanoic acid]cyclosporin A; cyclo[Abu-D-Ala-N(Me)Leu-N(Me)Leu-N(Me)Val-N(Me)Bmt(E)-Abu-Sar-N(Me)Leu-Val-N(Me)Leu]; cyclo[(N-(((2S)-2-aminobutyryl)-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-N-methyl-(4R)-4-[(E)-but-2-enyl]-4-methyl-L-threonyl)-(2S)-2-aminobutyryl)-sarcosyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl]. Grades: ≥90% by HPLC. CAS No. 108027-46-9. Molecular formula: C63H113N11O12. Mole weight: 1216.63. | |
Cytidine 3'(2')-Monophosphate Quick inquiry Where to buy Suppliers range | A metabolite of Cytidine. A highly specific phosphatase that acts on ADP-ribose 1''-phosphate, a metabolite of tRNA splicing in Saccharomyces cerevisiae. Synonyms: 3'(2')-Cytidylic Acid; 3'(2')-CMP; 3'(2')-Cytidinephosphoric Acid; 3'(2')-Cytosylic Acid; Ribocytidine 3'(2')-Monophosphate. Grades: 98%. Molecular formula: C9H14N3O8P. Mole weight: 323.2. | |
Deltamethrin Quick inquiry Where to buy Suppliers range | Synthetic pyrethroid insecticide, which acts as a potent inhibitor of calcineurin (protein phosphatase 2B) and has an IC50 of about 100pM. This inhibition action results in cellular hyperexcitability by causing non-mutated calcium channels to remain open for an extended period of time allowing an abundance of Ca2+ to enter the cell. Group: Biochemicals. Alternative Names: (1R, 3R) -3- (2, 2-Dibromoethenyl) -2, 2-di methyl cyclopropanecarboxylic Acid (S)-cyano(3-phenoxyphenyl)methyl Ester; Decamethrin; Esbecythrin; FMC-45498; NRDC-161. Grades: Highly Purified. CAS No. 52918-63-5. Pack Sizes: 500mg. US Biological Life Sciences. | Worldwide |
Deltamethrin-d5 (Mixture of Diastereomers) Quick inquiry Where to buy Suppliers range | Synthetic pyrethroid insecticide, which acts as a potent inhibitor of calcineurin (protein phosphatase 2B) and has an IC50 of about 100pM. This inhibition action results in cellular hyperexcitability by causing non-mutated calcium channels to remain open for an extended period of time allowing an abundance of Ca2+ to enter the cell. Group: Biochemicals. Alternative Names: (1R, 3R) -3- (2, 2-Dibromoethenyl) -2, 2-di methyl cyclopropanecarboxylic Acid (S)-cyano(3-phenoxyphenyl-d5)methyl Ester; Decamethrin-d5; Esbecythrin-d5; FMC-45498-d5; NRDC-161-d5. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
D-Homoarginine Hemisulfate Quick inquiry Where to buy Suppliers range | D-Homoarginine Hemisulfate is an enantiomer of L-Homoarginine, which is an inhibitor of alkaline phosphatase isoenzymes. Synonyms: N6-(Aminoiminomethyl)-D-lysine Hemisulfate Salt; (R)-2-Amino-6-guanidinohexanoic Acid Hemisulfate Salt. CAS No. 32733-73-6. Molecular formula: C14H34N8O8S. Mole weight: 474.54. | |
EDA-ADP - 5/6-TAMRA Quick inquiry Where to buy Suppliers range | EDA-ADP - 5/6-TAMRA, a fluorescently labeled nucleotide analogue, is a versatile tool with immense potential in the biomedicine field. Its application extends to studying protein-ligand interactions and enzyme kinetics, with a special focus on kinases and phosphatases associated with cancer and neurological disorders. The compound assists drug discovery researchers in designing and developing targeted drugs that aim to combat specific biomolecules associated with illnesses. Its significance and indispensability are undeniable in the quest towards unraveling the mysteries of various diseases. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-Adenosine-5'-diphosphate, labeled with 5/6-TAMRA, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C38H41N9O15P2(free acid). Mole weight: 925.74 (free acid). | |
Ertiprotafib Quick inquiry Where to buy Suppliers range | Ertiprotafib is an inhibitor of protein tyrosine phosphatase 1B (PTP1B), IkB kinase β (IKK-β), and a dual agonist of PPARα and PPARβ, with IC50s of 1.6 μM and 400 nM for PTP1B and IKK-β, and EC50s of ~1 μM for PPARα/PPAR&beta. It is potentially useful for the treatment of non-insulin dependent diabetes. Synonyms: PTP 112; Benzenepropanoic acid, α-[4-(9-bromo-2,3-dimethylnaphtho[2,3-b]thien-4-yl)-2,6-dimethylphenoxy]-, (αR)-; (2R)-2-(4-(9-Bromo-2,3-dimethylnaphtho(2,3-b)thiophen-4-yl)-2,6-dimethylphenoxy)-3-phenylpropionic acid; (αR)-α-[4-(9-Bromo-2,3-dimethylnaphtho[2,3-b]thien-4-yl)-2,6-dimethylphenoxy]benzenepropanoic Acid. Grades: 98%. CAS No. 251303-04-5. Molecular formula: C31H27BrO3S. Mole weight: 559.52. | |
Iso Cyclosporin H Trifluoroacetic Acid Salt Quick inquiry Where to buy Suppliers range | Iso Cyclosporin H Trifluoroacetic Acid Salt is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: (2S,3R,4R,6E)-3-Hydroxy-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-D-valine (11?1)-Lactone Trifluoroacetic Acid Salt; 10-(N-Methyl-D-valine)isocyclosporin A Trifluoroacetic Acid Salt; Cyclosporine Impurity 19 Trifluoroacetic Acid Salt; D-Valine, (2S,3R,4R,6E)-3-hydroxy-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-, (11?1)-lactone, Trifluoroacetic Acid Salt; Isocyclosporin H Trifluoroacetic Acid Salt. Grades: ≥90% by HPLC. Molecular formula: C62H111N11O12.C2HF3O2. Mole weight: 1316.63. | |
L-Homoarginine hydrochloride Quick inquiry Where to buy Suppliers range | L-Homoarginine is an alkaline phosphatase inhibitor found in blood, cerebrospinal fluid (CSF), and urine, as well as in human intestine and testes tissues. L-Homoarginine also acts as a substrate of CAT1, CAT2A and CAT2B, and CAT1 is a key site with regard to physiological relevance and interactions with related substrates such as L-arginine. Synonyms: NSC 145416; (S)-2-Amino-6-guanidinohexanoic acid hydrochloride. Grades: ≥95%. CAS No. 1483-01-8. Molecular formula: C7H16N4O2·HCl. Mole weight: 224.7. | |
L-Homoarginine, Hydrochloride (2-Amino-6-guanidino-hexanoic Acid, HCl) Quick inquiry Where to buy Suppliers range | An inhibitor of alkaline phosphatase isoenzymes. Group: Biochemicals. Alternative Names: 2-Amino-6-guanidino-hexanoic Acid, HCl. Grades: Highly Purified. CAS No. 1483-01-8. Pack Sizes: 2g. US Biological Life Sciences. | Worldwide |
LTV-1 Quick inquiry Where to buy Suppliers range | LTV-1, a highly potent inhibitor, inhibits LYP((IC50 = 508 nM)) in a dose-dependent manner at low- and sub-micromolar concentrations in T cells. Uses: Potent, cell-permeable and reversible inhibitor of lymphoid tyrosine phosphatase. Synonyms: LTV-1; LTV 1; LTV1; 3-[ (4-{ (E) -[1- (2-Methylphenyl) -4, 6-dioxo-2-thioxotetrahydro-5 (2H) -pyrimidinylidene]methyl}phenoxy) methyl]benzoic acid. Grades: ≥98%. CAS No. 347379-29-7. Molecular formula: C26H20N2O5S. Mole weight: 472.51. | |
Microcystin-LR Quick inquiry Where to buy Suppliers range | Microcystin-LR is a selective inhibitor of protein phosphatase 2A (PP2A) (IC50= 0.04 nM) and will completely inhibit this enzyme without affecting PP1 when used at a concentration of 0.5 nM.2 The PP1 IC50 is about 1.7 nM. Microcystins are at least 10 times more potent as serine/threonine PP inhibitors than okadaic acid, another microalgal toxin also used for this purpose. Uses: Enzyme inhibitors. Synonyms: Microcystin LR; Microcystin; Microcystin-a; MicrocystinLR; Cyanoginosin-LR; Toxin T 17; cyclo[2,3-didehydro-N-methylalanyl-D-alanyl-L-leucyl-(3S)-3-methyl-D-β-aspartyl-L-arginyl-(2S,3S,4E,6E,8S,9S)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyl-4,6-decadienoyl-D-γ-glutamyl]; 5-L-Arginine-microcystin LA; cyclo(Ala-Leu-MAsp-Arg-Adda-isoGlu-Mdha). Grades: >95%. CAS No. 101043-37-2. Molecular formula: C49H74N10O12. Mole weight: 995.17. | |
N-Acetyl-DL-Tyrosine Quick inquiry Where to buy Suppliers range | N-Acetyl-dl-tyrosine is a biologically active form of tyrosine that inhibits the activity of protein tyrosine phosphatases. Uses: Used for research and manufacturing. Group: Amino Acid Series. CAS No. 87-32-1. Product ID: PAP-0016. | |
N-Boc-propargylamine Quick inquiry Where to buy Suppliers range | N-Boc-propargylamine is used in the preparation of triazolobenzylidene-thiazolopyrimidines which act as CDC25 phosphatase inhibitors. Also used in the synthesis of β-glucan polysaccharide analogs. Group: Biochemicals. Alternative Names: N-2-Propyn-1-yl-carbamic Acid 1,1-Dimethylethyl Ester;2-Propynyl-carbamic Acid 1,1-Dimethylethyl Ester; 1,1-Dimethylethyl 2-Propyn-1-ylcarbamate; 2-Propynylcarbamic Acid tert-Butyl Ester; 3- (tert-Butoxycarbonylamino) prop-1-yne; 3-[ (tert-Butyloxycarbonyl) amino]-1-propyne; N-(Prop-2-ynyl)carbamic acid tert-butyl ester; N- (tert-Butoxycarbonyl) propargylamine; N-Boc-propargylamine; N-tert-Butoxycarbonyl-2-propyn-1-amine; tert-Butyl (2-Propyn-1-yl)carbamate; tert-Butyl 2-Propynylcarbamate; tert-Butyl N-Propargylcarbamate; tert-Butyl Propargylcarbamate. Grades: Highly Purified. CAS No. 92136-39-5. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |
Neomangiferin Quick inquiry Where to buy Suppliers range | Mangiferin and neomangiferin inhibited tartrate-resistant acid phosphatase, a biochemical marker of osteoclast function and bone resorption. Uses: Antioxidant. Synonyms: 2-(b-D-Glucopyranosyl)-7-(b-D-glucopyranosyloxy)-1,3,6-trihydroxy-9H-xanthen-9-one. Grades: >98%. CAS No. 64809-67-2. Molecular formula: C25H28O16. Mole weight: 584.48. | |
Nodularin Quick inquiry Where to buy Suppliers range | Nodularin is a pentapeptide toxin produced by the cyanobacterium Nodularia spumigena. It acts as a potent inhibitor of protein phosphatase types 1 (PP1) and 2A (PP2A), exhibiting IC50 values of 1.8 and 0.026 nM, respectively. Synonyms: Nodularin; Nodularin R; Nodularin-R; UNII-0979BIK2QU; 0979BIK2QU; HSDB 7749; DTXSID60880022; (2Z,5R,6S,9S,12S,13S,16R)-9-[3-(diaminomethylideneamino)propyl]-2-ethylidene-12-[(1E,3E,5S,6S)-6-methoxy-3,5-dimethyl-7-phenylhepta-1,3-dienyl]-1,6,13-trimethyl-3,7,10,14,19-pentaoxo-1,4,8,11,15-pentazacyclononadecane-5,16-dicarboxylic acid; Cyclo((Z)-2,3-didehydro-N-methyl-2-aminobutanoyl-erythro-3-methyl-D-beta-aspartyl-L-arginyl-(2S,3S,4E,6E,8S,9S)-4,5,6,7-tetradehydro-9-methoxy-2,6,8-trimethyl-10-phenyl-3-aminodecanoyl-D-gamma-glutamyl); Nodularin, cyanotoxin. Grades: ≥95%. CAS No. 118399-22-7. Molecular formula: C41H60N8O10. Mole weight: 825. | |
NSC87877 Quick inquiry Where to buy Suppliers range | NSC87877 is a cell-permeable, inhibitor of both SHP-1 and SHP-2 with IC50 values of 355nm and 318 nM, respectively. It shows effective growth inhibition and induction of apoptosis in NB cell lines. It is much less effective against other protein tyrosine phosphatases and the dual-specificity phosphatase 26. It blocks epidermal growth factor receptor-induced activation of Ras and ERK1/2 in HEK293 cells, stimulates store-operated calcium entry in response to thrombin in platelets, and increased acetylcholine receptor clustering in myotubes. Synonyms: NSC-87877; 5-Quinolinesulfonic acid, 8-hydroxy-7-(6-sulfo-2-naphthylazo)-; (E)-8-hydroxy-7-((6-sulfonaphthalen-2-yl)diazenyl)quinoline-5-sulfonic acid. Grades: >98 %. CAS No. 56990-57-9. Molecular formula: C19H13N3O7S2. Mole weight: 459.45. | |
Okadaic Acid Quick inquiry Where to buy Suppliers range | Okadaic Acid, a marine toxin, polyether derivative produced by dinoflagellates, is a potent, cell-permeable, specific inhibitor of PP-1 and PP-2 serine/threonine-speci?c protein phosphatases in a variety of cell types. Group: Biochemicals. Alternative Names: 9, 10-Deepithio-9, 10-dide hydroacanthifolicin, halochondrine A. Grades: Highly Purified. CAS No. 78111-17-8. Pack Sizes: 100ug. US Biological Life Sciences. | Worldwide |
Okadaic Acid Quick inquiry Where to buy Suppliers range | Okadaic acid is a marine sponge toxin which potently inhibits certain serine/threonine protein phosphatases. This cell permeable inhibitor targets the multiple isoforms of PP1, both isoforms of PP2A and PP3. It is a very weak inhibitor of PP2B and does not inhibit PP2C or other phosphatases. Synonyms: AA8227800; 9,10-Deepithio-9,10-didehydroacanthifolicin. Grades: 95% by HPLC. CAS No. 78111-17-8. Molecular formula: C44H68O13. Mole weight: 805.00. | |
Okadaic Acid Quick inquiry Where to buy Suppliers range | Okadaic acid is a protein phosphatase (PP) inhibitor derived from the marine. Group: Marine Chemicals. Alternative Names: 35-Demethyldinophysistoxin 1. Grades: 95%+. CAS No. 78111-17-8. Product ID: ACM78111178. Molecular formula: C44H68O13. Mole weight: 805. IUPAC Name: (2R)-3-[(2S,6R,8S,11R)-2-[(E,2R)-4-[(2S,2'R,4R,4aS,6R,8aR)-4-Hydroxy-2-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undecan-2-yl]butyl]-3-methylidenespiro[4a,7,8,8a-tetrahydro-4H-pyrano[3,2-b]pyran-6,5'-oxolane]-2'-yl]but-3-en-2-yl]-11-hydroxy-4-methyl-1,7-dioxaspiro[5.5]undec-4-en-8-yl]-2-hydroxy-2-methylpropanoic acid. Density: 1.0795 g/cm³. SMILES: CC1CCC2 (CCCCO2)OC1C (C)CC (C3C (=C)C (C4C (O3)CCC5 (O4)CCC (O5)C=CC (C)C6CC (=CC7 (O6)C (CCC (O7)CC (C) (C (=O)O)O)O)C)O)O. | |
Okadaic acid, Ammonium Salt (Halochondrine A, Ammonium, OA) Quick inquiry Where to buy Suppliers range | An ammonium salt form of the protein phosphatase inhibitor Okadaic acid with somewhat greater stability than the free acid when stored in organic solvents. Group: Biochemicals. Grades: Highly Purified. CAS No. 155716-06-6. Pack Sizes: 100ug. US Biological Life Sciences. | Worldwide |
Okadaic acid ammonium salt (High Purity) (Halochondrine A, CCRIS 3329, HSDB 7243, 9, 10-Deepithio-9, 10-dide hydroacanthifolicin) Quick inquiry Where to buy Suppliers range | Non-phorbol type tumor promoter. Reversible, potent and selective serine threonine protein phosphatase inhibitor. PP2A (IC50=0. 2-1nM), PP1 (IC50=3-15nM), PP2B (IC50= >1µM). Does not inhibit PP2C. Stimulates intracellular protein phosphorylation. Useful tool for studying cellular processes that are regulated by phosphorylation. Does not affect activity of acid phosphatase, alkaline phosphatase and tyrosine phosphatase. Mimics the effects of insulin. Activates atypical protein kinase C (zeta/lambda) in 3T3/L1 adipocytes. Enhances transmitter release at neuromuscular junctions. Apoptosis inhibitor. Induces apoptosis in human breast carcinoma cells (MB-231 and MCF-7) and in myeloid cells. Neurotoxic. Used to study various cellular processes including cell cycle, apoptosis, nitric oxide metabolism and calcium signaling. Stimulates cell motility, loss of stabilization of focal adhesions and a consequent loss of cytoskeletal organization. Source:Isolated from Prorocentrum concavum. Salt form generated in aqueous ammonium hydroxide-methanol solution. Group: Biochemicals. Alternative Names: Halochondrine A, CCRIS 3329, HSDB 7243, 9, 10-Deepithio-9, 10-dide hydroacanthifolicin. Grades: Highly Purified. CAS No. 155716-06-6. Pack Sizes: 25ug, 100ug. Molecular Formula: C44H67O13. NH4, Molecular Weight: 822. US Biological Life Sciences. | Worldwide |
Okadaic acid (High Purity) Quick inquiry Where to buy Suppliers range | Non-phorbol type tumor promoter. Reversible, potent and selective serine threonine protein phosphatase inhibitor. PP2A (IC50=0. 2-1nM), PP1 (IC50=3-15nM), PP2B (IC50=>1µM). Does not inhibit PP2C. Stimulates intracellular protein phosphorylation. Useful tool for studying cellular processes that are regulated by phosphorylation. Does not affect activity of acid phosphatase, alkaline phosphatase and tyrosine phosphatase. Mimics the effects of insulin. Activates atypical protein kinase C (zeta/lambda) in 3T3/L1 adipocytes. Enhances transmitter release at neuromuscular junctions. Apoptosis inhibitor. Induces apoptosis in human breast carcinoma cells (MB-231 and MCF-7) and in myeloid cells. Neurotoxic. Used to study various cellular processes including cell cycle, apoptosis, nitric oxide metabolism and calcium signaling. Stimulates cell motility, loss of stabilization of focal adhesions and a consequent loss of cytoskeletal organization. Source:Isolated from Prorocentrum concavum. Group: Biochemicals. Alternative Names: Halochondrine A, CCRIS 3329, HSDB 7243, 9, 10-Deepithio-9, 10-dide hydroacanthifolicin. Grades: Highly Purified. CAS No. 78111-17-8. Pack Sizes: 25ug, 100ug. Molecular Formula: C44H68O13, Molecular Weight: 805. US Biological Life Sciences. | Worldwide |
Okadaic acid potassium salt Quick inquiry Where to buy Suppliers range | Okadaic acid potassium salt, originally derived from marine dinoflagellates, Prorocentrium sp., is a potent, cell permeable inhibitor of serine/threonine protein phosphatases. It inhibits protein phosphatase 1 (IC50 = 3-15 nM) and protein phosphatase 2A (IC50 = 0.1-1 nM). Synonyms: 35-Demethyl-DTX 1 Potassium Salt. CAS No. 209266-79-5. Molecular formula: C44H68O13K. Mole weight: 844.10. | |
Okadaic acid potassium salt (Halochondrine A, CCRIS 3329, HSDB 7243, 9, 10-Deepithio-9, 10-dide hydroacanthifolicin) (High Purity) Quick inquiry Where to buy Suppliers range | Non-phorbol type tumor promoter. Reversible, potent and selective serine threonine protein phosphatase inhibitor. PP2A (IC50=0.2-1nM), PP1 (IC50=3-15nM), PP2B (IC50=>1uM). Does not inhibit PP2C. Stimulates intracellular protein phosphorylation. Useful tool for studying cellular processes that are regulated by phosphorylation. Does not affect activity of acid phosphatase, alkaline phosphatase and tyrosine phosphatase. Mimics the effects of insulin. Activates atypical protein kinase C (zeta/lambda) in 3T3/L1 adipocytes. Enhances transmitter release at neuromuscular junctions. Apoptosis inhibitor. Induces apoptosis in human breast carcinoma cells (MB-231 and MCF-7) and in myeloid cells. Neurotoxic. Used to study various cellular processes including cell cycle, apoptosis, nitric oxide metabolism and calcium signaling. Stimulates cell motility, loss of stabilization of focal adhesions and a consequent loss of cytoskeletal organization. Group: Biochemicals. Alternative Names: Halochondrine A, CCRIS 3329, HSDB 7243, 9, 10-Deepithio-9, 10-dide hydroacanthifolicin. Grades: Highly Purified. CAS No. 155751-72-7. Pack Sizes: 100ug. US Biological Life Sciences. | Worldwide |
Okadaic acid, Potassium Salt (Halochondrine A, Potassium, OA) Quick inquiry Where to buy Suppliers range | Potassium salt form of the protein phosphatase inhibitor Okadaic acid with somewhat greater stability than the free acid when stored in organic solvents. Group: Biochemicals. Grades: Highly Purified. CAS No. 155751-72-7. Pack Sizes: 100ug. US Biological Life Sciences. | Worldwide |