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AcidRed 18. Synonyms: New Coccine, AcidRed 18, Ponceau 4 R. CAS No. 2611-82-7. Pack Sizes: Bottomless glass bottle. Contents are inside inserted fused cone. Product ID: CDC10-0146. Molecular formula: C20H11N2O10S3Na3. Category: Cosmetic Color Additives. Product Keywords: Cosmetic Ingredients; Cosmetic Color Additives; AcidRed 18; CDC10-0146; 2611-82-7; C20H11N2O10S3Na3; New Coccine, AcidRed 18, Ponceau 4 R; 220-036-2; MFCD00004084; 2611-82-7. Purity: ≥98.0% (HPLC). Color: Bordeaux to brown. EC Number: 220-036-2. Physical State: Powder. Solubility: DMSO (Slightly, Heated, Sonicated), Methanol (Slightly, Heated), Water (Slightly. Quality Level: 100. Storage: Inert atmosphere,Room Temperature. Application: Ponceau 4R was used in the determination of contents of several additives in different non-alcoholic beverages using HPLC. It was used in understanding the genotoxicity of colorants. It was also used in preparing a falsified drink in the analysis of methanol-ethanol mixture using biosensors amperometric system. Melting Point: >300°C. Product Description: Ponceau 4R is a synthetic red azo dye and is used as a food colorant. It is used in range of alcoholic and non-alcoholic beverages, food stuffs, preserved fruits etc. It exists as trisodium-2-hydroxy-1-(4-sulfonato-1-naphthylazo)-6,8-naphthalenedisulfonate.
1-((3R,5R)-6-carboxy-3,5-dihydroxyhexyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Synonyms: 1-[(3R,5R)-6-Carboxy-3,5-dihydroxyhexyl]-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid; (βR,δR)-3-Carboxy-5-(4-fluorophenyl)-β,δ-dihydroxy-2-(1-methylethyl)-4-phenyl-1H-Pyrrole-1-heptanoic Acid. CAS No. 1821498-27-4. Molecular formula: C27H30FNO6. Mole weight: 483.53.
1-Naphthohydroxamic acid
1-Naphthohydroxamic acid (Compound 2) is a potent and selective HDAC8 inhibitor with an IC50 of 14 μM. 1-Naphthohydroxamic acid is more selectively for HDAC8 than class I HDAC1 and class II HDAC6 (IC50 >100 μM). 1-Naphthohydroxamic acid does not increase global histone H4 acetylation and also does not reduce total intracellular HDAC activity.1-Naphthohydroxamic acid can induce tubulin acetylation. Group: Inhibitors. CAS No. 6953-61-3. Molecular formula: C11H9NO2. Mole weight: 187.19. Purity: >98.0%(T). Catalog: ACM6953613.
2,2'-Diamino-4,4'-stilbenedicarboxylic acid
2,2'-Diamino-4,4'-stilbenedicarboxylic acid is an organic linker and an amine-functionalized dicarboxylic acid. It can be used in the formation of metal-organic frameworks (MOFs) for the storage of hydrogen and the reduction of CO2. Group: Hydrogen storage materials metal organic frameworks (mofs). CAS No. 1275552-69-6. Product ID: 3-amino-4-[(E)-2-(2-amino-4-carboxyphenyl)ethenyl]benzoic acid. Molecular formula: 298.29000000000002. Mole weight: (C21H9)n. C1=CC (=C (C=C1C (=O)O)N)C=CC2=C (C=C (C=C2)C (=O)O)N. 1S/C16H14N2O4/c17-13-7-11 (15 (19)20)5-3-9 (13)1-2-10-4-6-12 (16 (21)22)8-14 (10)18/h1-8H, 17-18H2, (H, 19, 20) (H, 21, 22)/b2-1+. QEDSDXRFNGAJKN-OWOJBTEDSA-N.
2,3-Dihydrothieno[3,4-b][1,4]dioxine-2-carboxylic acid, a promising antifungal agent, possesses potent activity against Candidiasis and Aspergillosis. The compound targets 3-ketoacyl-ACP synthase III (FabH), a key enzyme in the biosynthesis of fungal fatty acids, and reduces fungal growth by inducing cellular membrane disruption through inhibition of FabH activity. With its unique mode of action, 2,3-Dihydrothieno[3,4-b][1,4]dioxine-2-carboxylic acid stands as a notably effective potential antifungal therapeutic candidate. Synonyms: 2H,3H-Thieno[3,4-B][1,4]dioxine-2-carboxylic acid; EDOT carboxylic acid; Carboxyedot. CAS No. 955373-67-8. Molecular formula: C7H6O4S. Mole weight: 186.181.
2-Hydroxyadipic acid
2-Hydroxyadipic acid is an organic acid, formed by the reduction of 2-ketoadipic acid. Uses: Scientific research. Group: Natural products. CAS No. 18294-85-4. Pack Sizes: 10 mM * 1 mL; 25 mg. Product ID: HY-113101.
2-Mercapto-L-histidine
. Uses: An intermediate in the formation of l-egothioneine, a natural amino acid ubiquitously present in cells and tissues of most plants and mammalian species. in humans, l-ergothioneine is found in red blood cells, liver, kidney, brain, seminal fluid, and cata. Synonyms: L-His(2-mercapto)-OH. Grades: ≥ 98% (TLC). CAS No. 2002-22-4. Molecular formula: C6H9N3O2S. Mole weight: 187.20.
3,5-Dinitrosalicylic acid 99+% (HPLC)
3,5-Dinitrosalicylic acid (DNS) is used in colorimetric determination of reducing sugars and to analyze glycosidase (glycoside hydrolase) activity by quantitation of enzymatically released reducing sugar. The dinitrosalicylic acid method has been compared to the Nelson-Somogi colorimetric method. 3,5-Dinitrosalicylic acid (DNS) has been used to stop the reaction in in vitro α-amylase inhibition study. It has also been used for the quantitation of enzymatically released reducing sugars. Group: Biochemicals. Alternative Names: 2-Hydroxy-3,5-dinitro-benzoic Acid; 2-Hydroxy-3,5-dinitrobenzoic Acid; 3,5-Dinitro-2-hydroxybenzoic Acid; NSC 181. Grades: Highly Purified. CAS No. 609-99-4. Pack Sizes: 25g, 100g, 250g, 1Kg. Molecular Formula: C7H4N2O7. US Biological Life Sciences.
Worldwide
3-Bromo-5-phenyl salicylic acid
The aldo-keto reductase (AKR) enzymes constitute a family of related NADPH-dependent oxidoreductases. 3-Bromo-5-phenyl salicylic acid selectively inhibits AKR1C1 (Ki = 4 nM) over AKR1C2 (Ki = 87 nM), AKR1C3 (Ki = 4.2 μM), and AKR1C4 (Ki = 18.2 μM). Synonyms: NSC 109116; 3-bromo-2-hydroxy-5-phenylbenzoic acid. Grades: ≥95%. CAS No. 4906-68-7. Molecular formula: C13H9BrO3. Mole weight: 293.1.
4-(1',5'-Dihydro-1'-methyl-2'H-[5,6]fullereno-C60-Ih-[1,9-c]pyrrol-2'-yl)benzoic acid (C60-SAM) is a fullerene based self-assembled monolayer that can be used to functionalize the oxide surface for the formation electron selective layer (ECL). It can act as a good electron donor with a high electron affinity. It enhances the overall efficiency of perovskite solar cells (PSCs) by reducing the hysteresis. Uses: Fullerene-based self-assembled monolayers for use in organic electronic devices such as inverted polymer solar cells and perovskite-polymer hybrid solar cells. Group: Carbon nano materials organic solar cell (opv) materials. Alternative Names: C60-SAM. CAS No. 631918-72-4. Pack Sizes: 100 mg. Molecular formula: 897.84 g/mol. Mole weight: C70H11NO2. CN1CC23C4=C5C6=C7C4=C8C9=C4C% 10=C% 11C% 12=C% 13C% 10=C% 10C9=C7C7=C% 10C9=C% 10C% 14=C% 15C% 16=C% 17C (=C% 12C% 12=C% 17C% 17=C% 18C% 16=C% 16C% 15=C% 15C% 10=C7C6=C% 15C6=C% 16C7=C% 18C% 10=C (C2 (C1C1=CC=C (C=C1) C (=O) O) C7=C65) C1=C2C (=C4C8=C31) C% 11=C% 12C2=C% 17% 10) C% 14=C% 139. InChI= 1S / C70H11NO2 / c1-71-6-69-63-56-49-37-29-20-11-9-10- 12-15 (11) 24-31 (29) 39-40-32 (24) 30-21 (12) 23-19-14 (10) 17-16-13 (9) 18-22 (20) 35 (37) 43-41-27 (18) 25 (16) 33-34-26 (17) 28 (19) 42-44-36 (23) 38 (30) 50-52 (40) 61 (60 (63) 51 (39) 49) 65-58 (50) 55 (44) 59-48 (42) 46 (34) 53-45 (33) 47 (41) 57 (
Acid Blue 182, also known as C.I. Acid Blue 182, is a synthetic dye that belongs to the class of azo dyes. Uses: Acid blue 182 has been extensively studied for its application in various scientific research fields. it is used as a ph indicator in analytical chemistry, where it changes color from blue to red as the ph of the solution decreases. acid blue 182 is also used as a model compound in environmental studies to investigate the fate and transport of azo dyes in soil and water systems. Group: Acid dyes. Alternative Names: Alizarine Fast Blue ERL;C.I. Acid Blue 182;4-[[4-(Acetylmethylamino)-2-sulfophenyl]amino]-1-amino-9,10-dihydro-9,10-dioxo-2-anthracene sulfonic acid disodium salt;Blue HRL. CAS No. 12219-26-0. Molecular formula: C22H14N4Na2O9S2. Mole weight: 606.48. Appearance: Powder. IUPACName: disodium;4-[4-[acetyl(methyl)amino]-2-sulfonatoanilino]-1-amino-9,10-dioxoanthracene-2-sulfonate. Canonical SMILES: CC (=O)N (C)C1=CC (=C (C=C1)NC2=CC (=C (C3=C2C (=O)C4=CC=CC=C4C3=O)N)S (=O) (=O)[O-])S (=O) (=O)[O-]. [Na+]. [Na+]. Catalog: ACM12219260.
Alfa Chemistry offers AcidRed 92 products for various research purposes. Please contact us by email if you do not find the specification you are looking for on this page. Uses: Applications of xanthene dyes involve optical materials and organic dyes for medical diagnosis research. several characteristic features of xanthene dyes are large absorption and luminescence, excellent light resistance, low toxicity in-vivo, and relatively high solubility in water. Group: Acid dyes. Alternative Names: Phloxine B 2',4',5',7'-Tetrabromo-3,4,5,6-tetrachlorofluorescein Sodium Salt. CAS No. 18472-87-2. Molecular formula: C20H2Br4Cl4Na2O5. Mole weight: 829.63. Appearance: Dark red to Brown powder to crystal. Purity: >85.0%(E). Catalog: ACM18472872.
AcidRed 92
Alfa Chemistry offers AcidRed 92 products for various research purposes. Please contact us by email if you do not find the specification you are looking for on this page. Uses: Applications of xanthene dyes involve optical materials and organic dyes for medical diagnosis research. several characteristic features of xanthene dyes are large absorption and luminescence, excellent light resistance, low toxicity in-vivo, and relatively high solubility in water. Group: Xanthene dyes. Alternative Names: Phloxine B 2',4',5',7'-Tetrabromo-3,4,5,6-tetrachlorofluorescein Sodium Salt. CAS No. 18472-87-2. Molecular formula: 829.63. Mole weight: C20H2Br4Cl4Na2O5. >85.0%(E).
AKR1C1 Inhibitor, 5-PBSA
A cell-permeable salicylic acid compound that acts as a highly potent, active-site directed and substrate competitive AKR1C1 inhibitor (Ki=4nM) with moderate to excellent selectivity over AKR1C2, AKR1C3 and AKR1C4 (Ki=0.087, 4.2 and 18.2uM, respectively). Shown to inhibit the metabolism of progesterone by AKR1C1 (IC50=460nM in AKR1C1 overexpressing BAECs).CAS No.4906-68-7. Group: Biochemicals. Alternative Names: Aldo-Keto Reductase family 1 member C1 Inhibitor, 5-PBSA, 3-Bromo-5-phenylsalicylic acid, 20α-Hydroxysteroid Dehydrogenase Inhibitor, 5-PBSA. Grades: Highly Purified. CAS No. 4906-68-7. Pack Sizes: 25mg. Molecular Formula: C??H?BrO?. US Biological Life Sciences.
Worldwide
Apamin
Apamin is an 18 amino acid peptide toxin found in bee venom. Apamin is used to elucidate the roles of these channels in cells and tissues expressing SK channels, including neurons, vascular endothelium, bladder smooth muscle, and certain types of cancer cells. Synonyms: Apamin (reduced), cyclic(1?11),(3?15)-bis(disulfide); Apamine; H-Cys(1)-Asn-Cys(2)-Lys-Ala-Pro-Glu-Thr-Ala-Leu-Cys(1)-Ala-Arg-Arg-Cys(2)-Gln-Gln-His-NH2; L-cysteinyl-L-asparagyl-L-cysteinyl-L-lysyl-L-alanyl-L-prolyl-L-alpha-glutamyl-L-threonyl-L-alanyl-L-leucyl-L-cysteinyl-L-alanyl-L-arginyl-L-arginyl-L-cysteinyl-L-glutaminyl-L-glutaminyl-L-histidinamide (1->11),(3->15)-bis(disulfide); Apamin, Bee Venom. Grades: ≥95% (HPLC). CAS No. 24345-16-2. Molecular formula: C79H131N31O24S4. Mole weight: 2027.34.
AS 1842856
AS 1842856 is a potent and selective inhibitor of Forkhead box protein O1 transcription factor (FoxO1; IC50 = 33 nM). AS 1842856 reduces glucose production in dose manner via the inhibition of glucose-6 phosphatase and phosphoenolpyruvate carboxykinase mRNA levels in a rat hepatic cell line. AS 1842856 is promisingly to be a therapy of type 2 diabetes mellitus and obesity. Uses: Potential treatment of type 2 diabetes mellitus and obesity. Synonyms: AS1842856; AS-1842856; AS 1842856. 5-amino-7-(cyclohexylamino)-1-ethyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid. Grades: 99%. CAS No. 836620-48-5. Molecular formula: C18H22FN3O3. Mole weight: 347.38.
Azelaic Acid
Azelaic acid is a synthetic dicarboxylic acid that is commonly used in the treatment of acne and rosacea. It is also sometimes prescribed for other skin conditions, such as hyperpigmentation and melasma. Azelaic acid works by inhibiting the growth of acne-causing bacteria on the skin, reducing inflammation, and helping to unclog pores. It is also a mild exfoliant, which helps to remove dead skin cells and improve skin texture. Uses: 1. treatment of acne: azelaic acid is commonly used as a topical treatment for mild to moderate acne. it works by reducing the growth of bacteria that causes acne, and it also helps to unclog pores and reduce inflammation. 2. treatment of rosacea: azelaic acid also has anti-inflammatory properties that make it an effective treatment for rosacea, a chronic skin condition that causes facial redness. Group: Resin additives. Alternative Names: Anchoec acid. CAS No. 123-99-9. Product ID: Nonanedioic acid. Molecular formula: 188.22. Mole weight: C9H16O4. C(CCCC(=O)O)CCCC(=O)O. InChI=1S/C9H16O4/c10-8 (11)6-4-2-1-3-5-7-9 (12)13/h1-7H2, (H, 10, 11) (H, 12, 13). BDJRBEYXGGNYIS-UHFFFAOYSA-N. 98%.
BAY 1436032
BAY-1436032 is a highly selective, potent and orally available inhibitor of mutant Isocitrate Dehydrogenase 1 (mIDH1). It is a double-digit nanomolar and selective pan-inhibitor of the enzymatic activity of various IDH1-R132X mutants in vitro and displays potent inhibition of 2-HG release (nanomolar range) in patient derived and engineered cell lines expressing different IDH1 mutants. BAY 1436032 strongly reduces 2-HG (2-hydroxyglutarate) levels in cells carrying IDH1-R132H, -R132C, -R132G, -R132S and -R132L mutations. BAY 1436032 showed a favourable selectivity profile against wtIDH1/2 and a large panel of off-targets in vitro. Synonyms: 3-(2-[[4-(Trifluoromethoxy)phenyl]amino]-1-[(1R,5R)-3,3,5-trimethylcyclohexyl]-1H-benzimidazol-5-yl)propanoic Acid; BAY-1436032. Grades: ≥98%. CAS No. 1803274-65-8. Molecular formula: C26H30F3N3O3. Mole weight: 489.53.
Caracemide
Caracemide is an agent derived from acetohydroxamic acid. It has potential antineoplastic activity. Caracemide can inhibit ribonuclease reductase, resulting in decreased DNA synthesis and tumor growth. But in Feb 1995, Phase II for Cancer in USA was discontinued. Uses: Cancer. Synonyms: NSC 253272; NSC253272; NSC-253272; N-(methylcarbamoyl)-N-((methylcarbamoyl)oxy)acetamide. Grades: 98%. CAS No. 81424-67-1. Molecular formula: C6H11N3O4. Mole weight: 189.17.
Carboxypeptidase B from Porcine, Recombinant
Carboxypeptidase B (or peptidyl-L-lysine (-L-arginine) hydrolase) catalyzes the hydrolysis of the basic amino acids, lysine, arginine, and ornithine from the C-terminal position of polypeptides. It has been shown to be a single polypeptide of 34 kDa Da. Trypsin is capable of converting native enzyme to the active enzyme, carboxypeptidase B II in vitro. The optimum pH is found to be 9.0. The enzyme may be used for sequence analysis by successive cleavage of C-terminal basic amino acids. It can also be used as a serum marker for the diagnosis of acute pancreatitis. Carboxypeptidase b (ec 3.4.17.2), also well known as protaminase, pancreatic procarboxy-peptidase b (pcpb), ... mature chain. the secreted cpb zymogen is converted to enzymatically active cpb by limited proteolysis by trypsin. Group: Enzymes. Synonyms: carboxypeptidase B; protaminase; CPB1; pancreatic carboxypeptidase B; tissue carboxypeptidase B; peptidyl-L-lysine [L-arginine]hydrolase; EC 3.4.17.2; 9025-24-5. Enzyme Commission Number: EC 3.4.17.2. Purity: >90% (SDS-PAGE test). Mole weight: About 35kDa (SDS-PAGE detection). Activity: >180U/mg. Appearance: White powder, lyophilized. Storage: Redissolved in 20% glycerol, 4°C, store at -20°C for long-term preservation, Avoid multiple freeze-thaw cycles. Form: Freeze dried powder. Source: Porcine. carboxypeptidase B; protaminase; C
CGP 23996
CGP 23996 is a non-reducible somatostatin analog. It can be used for autoradiography. Uses: Autoradiography. Synonyms: CGP 23996; CGP23996; CGP-23996. BDBM82467; 2-Deamino-L-Abu(1)-L-Lys-L-Asp(NH2)-L-Phe-L-Phe-L-Trp-L-Lys-L-Thr-L-Tyr-L-Thr-L-Ser-L-Abu(1)-OH;(14R,20S,23R,26R,29R,32R)-2,17-bis(4-aminobutyl)-5-(2-amino-2-oxoethyl)-8,11-dibenzyl-20,26-bis[(1S)-1-hydroxyethyl]-29-(hydroxymethyl)-23-[(4-hydroxyphenyl)methyl]-14-(1H-indol-3-ylmethyl)-3,6,9,12,15,18,21,24,27,30,38-undecaoxo-1,4,7,10,13,16,19,22,25,28,31-undecazacyclooctatriacontane-32-carboxylic acid. Grades: 98%. CAS No. 86170-12-9. Molecular formula: C73H99N15O18. Mole weight: 1474.66.
CHF 5074
CHF 5074 is a novel γ-secretase modulator. It reduces Aβ42 and Aβ40 secretion with IC50 values of 3.6 and 18.4 μM respectively. It protects SH-SY5Y human neuronal-like cells from amyloidbeta 25-35 and tumor necrosis factor related apoptosis inducing ligand toxicity in vitro. Uses: Chf5074 induces microglia alternative activation in plaque-free tg2576 mice and primary glial cultures exposed to beta-amyloid. it restores visual memory ability and pre-synaptic cortical acetylcholine release in pre-plaque tg2576 mice. it is a non-steroidal anti-inflammatory derivative holding disease-modifying potential for the treatment of alzheimer's disease. it significantly reduces the apoptosis in hippocampal neurons exposed to ogd, as revealed by cleaved-caspase-3 immunoreactivity and tunel staining. Synonyms: CHF-5074; Itanapraced; 1-[4-(3,4-dichlorophenyl)-3-fluorophenyl]cyclopropane-1-carboxylic acid. Grades: >98%. CAS No. 749269-83-8. Molecular formula: C16H11Cl2FO2. Mole weight: 325.16.
Chlorhexidine Digluconate
Chlorhexidine digluconate is the salt of Chlorhexidine, which is a disinfectant and topical anti-infective agent for reduction of pocket depth in patients with adult periodontitis. Uses: Anti-infective agents, local. Synonyms: Chlorhexidine bigluconate; Chlorhexidine gluconate; Hibiclens; Peridex; Unisept; Chlorhexidine D-digluconate; Exidine; Periogard; N, N''''-1, 6-Hexanediylbis[N'- (4-chlorophenyl) (imidodicarbonimidicdiamide)] D-gluconic acid (1:2); 1,6-bis(4-Chlorophenyldiguanino)hexane digluconate; 1,1'-Hexamethylenebis(5-[p-chlorophenyl]biguanide); Bis(p-chlorophenyl)diguanidohexane digluconate. Grades: ≥95%. CAS No. 18472-51-0. Molecular formula: C22H30Cl2N10.2C6H12O7. Mole weight: 897.76.
Colesevelam hydrochloride
Colesevelam (hydrochloride) is a bile acid sequestrant that bind bile acids in the gut. Colesevelam (hydrochloride) inhibits bile acid reabsorption, leading to increased bile acid synthesis and reduced cholesterol levels in patients with cholestatic pruritus and Crohns disease. Uses: Scientific research. Group: Signaling pathways. CAS No. 182815-44-7. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106539.
Colesevelam hydrochloride
Colesevelam is a bile acid sequestrant that helps reduce elevated low-density lipoprotein cholesterol (LDL-C) in patients with primary hyperlipidemia, and also improve blood glucose balance in adults with type 2 diabetes mellitus. Synonyms: CholestaGel; GT 31-104; GT 31-104HB; Welchol. CAS No. 182815-44-7. Molecular formula: (C13H27N)n. (C12H27ClN2)n. (C3H7N)n. (C3H5ClO)n. xHCl.
Cyclopiazonic acid
Cyclopiazonic acid is an endoplasmic reticulum calcium ATPase (ECAs) inhibitor and human respiratory syncytial virus (RSV) inhibitor ( EC 50 value of 4.13 μ M), which can reduce the antagonistic effect of 5-HT receptors in rat thoracic aorta, induce p53 dependent cell apoptosis and reproductive toxicity in mouse testes, and inhibit the biological activation of aflatoxin B [1][4][5]. Uses: Scientific research. Group: Natural products. CAS No. 18172-33-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-N6771.
Daglutril
Daglutril is a dual endothelin converting enzyme (ECE)/neutral endopeptidase (NEP) inhibitor used for the treatment of hypertension and heart failure andpulmonary. It reduces proteinuria and urinary albumin excretion in diabetic rats, and inhibits systemic conversion of big endothelin-1 in humans. Synonyms: SLV-306; SLV306; SLV 306; 2- [ (3S) -3- [ [1- [ (2R) -2-ethoxycarbonyl-4-phenylbutyl] cyclopentanecarbonyl] amino] -2-oxo-4, 5-dihydro-3H-1-benzazepin-1-yl] acetic acid. Grades: 99%. CAS No. 182821-27-8. Molecular formula: C31H38N2O6. Mole weight: 534.64.
Deserpidine
Deserpidine is an antihypertensive drug related to Reserpine. It is naturally found in Rauvolfia spp. Deserpidine is a competitive ACE (angiotensin converting enzyme) inhibitor. Deserpidine can block the conversion of angiotensin I to angiotensin II as a potent vasoconstrictor through competing with angiotensin I for ACE. Reduced level of serum angiotensin II leads to a decrease in blood pressure. Deserpidine can also decrease angiotensin II-induced aldosterone secretion by the adrenal cortex. Uses: Antihypertensive drug. Synonyms: (3β, 16β, 17α, 18β, 20α)-17-methoxy-18-[(3, 4, 5-trimethoxybenzoyl)oxy]yohimban-16-carboxylic Acid Methyl Ester; Deserpidic Acid Methyl Ester 3,4,5-Trimethoxybenzoate; Deserpidin; 1-Demethoxyreserpine; 11-Desmethoxyreserpine; Canescin; Canescine; Canescine (Rauwolfia); Harmonyl; NSC 72138; Raunormin; Raunormine; Recanescin; Recanescine; Reserpidine. Grades: 95%. CAS No. 131-01-1. Molecular formula: C32H38N2O8. Mole weight: 578.66.
Dihydrofolate Reductase from human, Recombinant
Dihydrofolate reductase, or DHFR, is an enzyme that reduces dihydrofolic acid to tetrahydrofolic acid, using NADPH as electron donor, which can be converted to the kinds of tetrahydrofolate cofactors used in 1-carbon transfer chemistry. In humans, the DHFR enzyme is encoded by the DHFR gene. It is found in the q11?q22 region of chromosome 5. Bacterial species possesses distinct DHFR enzymes (based on their pattern of binding diaminoheterocyclic molecules), but mammalian DHFRs are highly similar. Human dhfr is an 186 amino acid protein with an apparent molecular weight of 25 kda. it is 30% homologous to the e. coli protein and up to 70% homologous to vertebrate protein... from mycobacterium smegmatis. human dihydrofolate reductase has been used in a study to investigate the stable expression of green fluorescent protein and the targeted disruption of thioredoxin peroxidase-1 gene in babesia bovis. human dihydrofolate reductase has also been used in a study to investigate the structural analysis of human dihydrofolate reductase as a binary complex. Group: Enzymes. Synonyms: DHFR; dihydrofolate reductase; DYR; DHFRP1; Tetrahydrofolate NADP+ oxidoreductase; EC 1.5.1.3; tetrahydrofolate dehydrogenase; pteridine reductase:dihydrofolate reductase; dihydrofolate reductase:thymidylate synthase; thymidylate synthetase-dihydrofolate reductase; f
enoyl-[acyl-carrier-protein] reductase (NADH)
The enzyme catalyses an essential step in fatty acid biosynthesis, the reduction of the 2,3-double bond in enoyl-acyl-[acyl-carrier-protein] derivatives of the elongating fatty acid moiety. The enzyme from the bacterium Escherichia coli accepts substrates with carbon chain length from 4 to 18. The enzyme from the bacterium Mycobacterium tuberculosis prefers substrates with carbon chain length from 12 to 24 carbons. Group: Enzymes. Synonyms: enoyl-[acyl carrier protein] reductase; enoyl-ACP reductase; NADH-enoyl acyl carrier protein reductase; NADH-specific enoyl-ACP reductase; acyl-[acyl-carrier-protein]:NAD+ oxidoreductase; fabI (gene name); inhA (gene name). Enzyme Commission Number: EC 1.3.1.9. CAS No. 37251-08-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1359; enoyl-[acyl-carrier-protein] reductase (NADH); EC 1.3.1.9; 37251-08-4; enoyl-[acyl carrier protein] reductase; enoyl-ACP reductase; NADH-enoyl acyl carrier protein reductase; NADH-specific enoyl-ACP reductase; acyl-[acyl-carrier-protein]:NAD+ oxidoreductase; fabI (gene name); inhA (gene name). Cat No: EXWM-1359.
Fimaporfin
Fimaporfin, a potent chlorin-based photosensitizer, is consisted of a mixture of three isomers A, B and C (25%,50%,25%). Fimaporfin has been developed by di-imide reduction of disulfonated tetraphenyl porphine (TPPS(2a)). The synthesized TPCS(2a) contains 3 isomers as shown by HPLC with low inter-batch variation with respect to isomer formation, less than 0.5% (w/w) of the starting material TPPS(2a) and absorbs light at 652nm. TPCS(2a) was found to be a clinically suitable PCI photosensitizer for photochemical activation of molecules that do not readily penetrate the cellular plasma membrane. Synonyms: Benzenesulfonic acid, 4,4'-[7,8(or 17,18)-dihydro-10,15(or 15,20)-diphenyl-21H,23H-porphine-5,20(or 5,10)-diyl]bis-; 4,4'-[7,8(or 17,18)-Dihydro-10,15(or 15,20)-diphenyl-21H,23H-porphine-5,20(or 5,10)-diyl]bis[benzenesulfonic acid]. CAS No. 1443547-43-0. Molecular formula: C132H96N12O18S6. Mole weight: 2330.63.
Food Red No. 102
Food Red No. 102. Group: Biochemicals. Alternative Names: 7-Hydroxy-8-[2-(4-sulfo-1-naphthalenyl)diazenyl]-1,3-naphthalenedisulfonic Acid Trisodium Salt; C.I. AcidRed 18; Cochineal Red 4R; New Coccine; Coccin Red; Takaoka Brilliant Scarlet 3R; Triacid Ponceau 4R; Triacid Scarlet 3R; Trisodium 1-(4-sulfo-1-naphthylazo)-2-naphthol-6,8-disulfonate; Vicoacid Scarlet 3R; Victoria Scarlet 3R; Victoria Scarlet Red. Grades: Highly Purified. CAS No. 2611-82-7. Pack Sizes: 5g. Molecular Formula: C20H11N2Na3O10S3, Molecular Weight: 604.47. US Biological Life Sciences.
Worldwide
Free Methionine-(R)-Sulfoxide Reductase from E. coli, recombinant
The Free Methionine-(R)-Sulfoxide Reductase (fRMsr) reduces free methionine sulfoxide (Met(O)) to methionine using thiol-disulfide exchange chemistry. This enzyme is involved in oxidative defense and known to form a sulfenic acid intermediate at the active site Cys during the course of turnover. In this variant, all Cys other than the peroxide-sensitive Cys have been removed by mutagenesis in order to stabilize the active site sulfenic acid with respect to disulfide bond formation. Applications: Free methionine-(r)-sulfoxide reductase (c84s, c94s), or frmsr, can be selectively derivatized at a single cys residue with a variety of cys-soh specific probes and be used as a positive control. Group: Enzymes. Enzyme Commission Number: EC 1.8.4.14. Purity: >98% by SDS-PAGE. Mole weight: 18,752 Da. Storage: at -80 °C. Form: Liquid. Source: E. coli. Free Methionine-(R)-Sulfoxide Reductase; fRMsr; EC 1.8.4.14. Cat No: NATE-1693.
Gallium(III) oxide
Gallium sesquioxide is reduced to gallium suboxide, Ga2O [12024-20-3] by common reducing agents. Also, heating the sesquioxide with gallium metal yields gallium suboxide. Heating with magnesium reduces the oxide to elemental form in a violent reaction: Ga2O3 + 3Mg →2Ga + 3MgO Heating with mineral acids yields corresponding gallium salts. When heated with a mixture of hydrogen and arsenic vapors at 600°C, gallium arsenide, GaAs is produced. When heated with alkali metal oxide at 1,000°C, alkali metal gallates, such as K2Ga2O6 are formed. Group: Nanoparticles & nanopowders. Alternative Names: Digallium trioxide. CAS No. 12024-21-4. Molecular formula: Ga2O3. Mole weight: 187.44. Appearance: White Powder. Purity: 99%, 99.9%, 99.99%, 99.999%. IUPACName: oxo(oxogallanyloxy)gallane. Density: 5.88 g/cm³. Catalog: ACM12024214.
Gemcabene
Gemcabene is an orally available lipid-lowering small molecule designed to target known lipid metabolic pathways, as an adjunctive therapy to reduce LDL-C, hsCRP and triglycerides (TGs). Currentl, Gemcabene is under Phase-II clinical trials in Hypertriglyceridaemia in USA. Synonyms: 6-(5-carboxy-5-methyl-hexoxy)-2,2-dimethyl-hexanoic acid; gemcabene; 6,6'-oxybis(2,2-dimethylhexanoic acid); PD72953; PD 72953; PD-72953. Grades: >98%. CAS No. 183293-82-5. Molecular formula: C16H30O5. Mole weight: 302.41.
A pyridinyl -pyrimidinyl aminopropanoic acid that effectively inhibits KDM6 family H3K27m3 demethylases JMJD3 and UTX (IC50 = 18 and 56uM, respectively, by MALDI Mass detection) in an alpha-ketoglutarate-competitive, peptide substrate-non-competitive manner, displaying much reduced potency against JARID1C, JMJD1a, JMJD2a, JMJD2c, JMJD2d, JMJD2e, as well as112 kinases and 60 non-kinase enzymes. Recommended for cell-free assays only. For culture treatment, use the cell-permeable pro-drug GSK-J4. Group: Biochemicals. Grades: Highly Purified. CAS No. 1373422-53-7. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
HX 531
HX 531 is a potent RXR antagonist (IC50 = 18 nM) that inhibits 9-cis retinoic acid-induced transactivation of RXR. HX 531 promotes the differentiation of white and brown pre-adipocyte to white adipocytes, and reduces triglyceride content in white adipose tissue, skeletal muscle, and the liver of mice given a high fat diet. Synonyms: HX 531; HX-531; HX531. 4-(7,8,9,10-Tetrahydro-5,7,7,10.10-pentamethyl-2-nitro-5H-benzo[b]naphtho[2,3-e][1,4]-diazepin-12-yl)-benzoic acid. Grades: ≥98% by HPLC. CAS No. 188844-34-0. Molecular formula: C29H29N3O4. Mole weight: 483.56.
JTP 103237
JTP 103237 is a potent and selective monoacyglycerol acyltransferase 2 (MGAT2) inhibitor (IC50 = 20-40 nM), exhibiting >7000-fold selectivity for human MOGAT2 over human DGAT2. In a high sucrose very low fat (HSVLF) diet induced fatty liver model, JTP-103237 reduced hepatic triglyceride content and hepatic MGAT activity, suppressed not only triglyceride (TG) and diacylglycerol (DG) synthesis, but also fatty acid (FA) synthesis (de novo lipogenesis). Synonyms: 7-[4,6-Bis(1,1-dimethylethyl)-2-pyrimidinyl]-5,6,7,8-tetrahydro-3-[4-(trifluoromethoxy)phenyl]-1,2,4-triazolo[4,3-a]pyrazine. Grades: ≥98% by HPLC. CAS No. 1883864-16-1. Molecular formula: C24H29F3N6O. Mole weight: 474.52.
L-Gulono-1,4-lactone-13C6
L-Gulono-1,4-lactone-13C6. Group: Biochemicals. Alternative Names: Reduced Ascorbic Acid-13C; Dihydroascorbic Acid-13C. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: 13C6H10O6, Molecular Weight: 184.1. US Biological Life Sciences.
Worldwide
Linoleic acid-13C18
Linoleic acid- 13 C 18 is the 13 C labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism [1][2]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 287111-25-5. Pack Sizes: 500 μg; 1 mg. Product ID: HY-N0729S2.
L-Lysine hydrochloride
L-lysine hydrochloride is an essential amino acid for humans with various benefits including treating herpes, increasing calcium absorption, reducing diabetes-related illnesses and improving gut health. Group: Inhibitors. Alternative Names: L-Lysine monohydrochloride. CAS No. 657-27-2. Molecular formula: C6H14N2O2.HCl. Mole weight: 182.65. Appearance: White to off-white powder. Purity: 0.985. IUPACName: (2S)-2,6-diaminohexanoic acid;hydrochloride. Canonical SMILES: C(CCN)C[C@@H](C(=O)O)N.Cl. Density: 1.28 g/ml. Catalog: ACM657272.
Lycopene
Lycopene, in the concentration used, is not toxic and also its health benefits in adipose tissue may play a role against obesity-related complications. Lycopene in tomato puree has decreased indicating an indirect effect on lycopene stability caused by high concentration of hydrogen peroxide and the activation of peroxidase enzymes leading to the reduction of ascorbic acid and its regenerative action towards lycopene. Besides, Lycopene protected β-carotene against isomerization during reactions with singlet oxygen and radicals. These findings can explain the pattern of carotenoid isomers analyzed in fruits and vegetables, where lycopene containing samples showed higher (all-E)/(9Z)-β-carotene ratios, and also in in vivo samples such as human blood plasma. Lycopene can be used as pigment in food processing, and is also used as raw material of antioxidant health food. Uses: Ingredient of health care products. Synonyms: ψ,ψ-Carotene; all-trans-Lycopene; Lyco Vit; Lycopene 7; Lycored; NSC 407322; Redivivo; trans-Lycopene; (all-E)-2,6,10,14,19,23,27,31-Octamethyl-2,6,8,10,12,14,16,18,20,22,24,26,30-dotriacontatridecaene. Grades: 96%. CAS No. 502-65-8. Molecular formula: C40H56. Mole weight: 536.87.
mPEG6-Propionic acid
Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation. Uses: Activated peg derivatives can be used to modify peptides, proteins, or in other bioconjugation applications. pegylated materials have found broad use in drug delivery systems, virology, and immunology, as the incorporation of peg improves pharmacological properties such as increased water solubility, enhanced resistance to degradation (protein hydrolysis), increased circulation half-life, and redu. Group: Poly(ethylene glycol) and poly(ethylene oxide). Product ID: 3- [2- [2- [2- [2- [2- (2-methoxyethoxy) ethoxy] ethoxy] ethoxy] ethoxy] ethoxy] propanoic acid. Molecular formula: 368.42g/mol. Mole weight: C16H32O9. COCCOCCOCCOCCOCCOCCOCCC(=O)O. InChI= 1S / C16H32O9 / c1-19-4-5-21-8-9-23-12-13-25-15-14-24 -11-10-22-7-6-20-3-2-16 (17) 18 / h2-15H2, 1H3, (H, 17, 18). NOPQIPMESCUIHH-UHFFFAOYSA-N.
Native Lactobacillus delbrückii D-Lactate Dehydrogenase, Grade I
In enzymology, a D-lactate dehydrogenase is an enzyme that catalyzes the chemical reaction: (D)-lactate + 2 ferricytochrome c<-> pyruvate + 2 ferrocytochrome c. Thus, the two substrates of this enzyme are (D)-lactate and ferricytochrome c, whereas its two products are pyruvate and ferrocytochrome c. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with a cytochrome as acceptor. This enzyme participates in pyruvate metabolism. It employs one cofactor, FAD. Dehydrogenase that catalyzes the interconversion of d(-)-lactate to pyruvate. rely on the proven diagnostic quality of this product. benefit from the...ase; D-lactate (cytochrome) dehydrogenase; cytochrome-dependent D-(-)-lactate dehydrogenase; D-lactate-cytochrome c reductase; D-(-)-lactic cytochrome c reductase. CAS No. 9028-36-8. D-LDH. Activity: >180 U/mg. Stability: At +2 to +8°C within specification range for 12 months. Store dry. Appearance: White to yellowish lyophilizate. Source: Lactobacillus delbrückii. EC 1.1.1.28; D-Lactic Dehydrogenase; 9028-36-8; (D)-lactate:ferricytochrome-c 2-oxidoreductase; lactic acid dehydrogenase; D-lactate (cytochrome) dehydrogenase; cytochrome-dependent D-(-)-lactate dehydrogenase; D-lactate-cytochrome c reductase; D-(-)-lactic cytochrome c reductase. Cat No: NATE-0976.
Phloxine B Certified
Phloxine B Certified. Group: Biochemicals. Alternative Names: Cyanosine; Eosin 1B; Acidred 92; CI 4541. Grades: Highly Purified. CAS No. 18472-87-2. Pack Sizes: 50g, 100g, 250g, 500g, 1kg. Molecular Formula: C20H2Br4Cl4O5Na2. US Biological Life Sciences.
Worldwide
Pitavastatin Impurity 18 Sodium Salt
Pitavastatin Impurity 18 Sodium Salt (Pitavastatin N-Oxide Sodium Salt) is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: (3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-1-oxido-3-quinolinyl]-3,5-dihydroxy-6-heptenoic acid, sodium salt (1:1); Pitavastatin N-Oxide Sodium Salt. CAS No. 2276678-27-2. Molecular formula: C25H23FNO5Na. Mole weight: 459.44.
Ponceau 4R
Ponceau 4R is a synthetic colorant that can be used for food coloring. Ponceau 4R is a strawberry red azo dye that can be used in a variety of foods, usually synthesized from aromatic hydrocarbons, and is stable to light, heat, and acids [1] [2]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: AcidRed 18; New Coccine. CAS No. 2611-82-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-D0193.
Raloxifene-4' -glucuronide
A metabolite of Raloxifene. Raloxifene is selective estrogen receptor modulator. It can be used in the prevention of osteoporosis in postmenopausal women and to reduce the risk of invasive breast cancer in postmenopausal women with osteoporosis and in postmenopausal women at high risk for invasive breast. Synonyms: 4-[6-Hydroxy-3-[4-2[2- (1-piperindinyl) ethoxy]benzoyl]benzo[b]thien-2-yl]phenyl-b-D-glucopyranosiduronic acid. Grades: > 95%. CAS No. 182507-22-8. Molecular formula: C34H35NO10S. Mole weight: 649.71.
(R)-Desethyl oxybutynin HCl
An impurity of Oxybutynin which reduces muscle spasms of the bladder and urinary tract. Synonyms: (R)-N-Desethyl Oxybutynin Hydrochloride; (αR)-α-Cyclohexyl-α-hydroxybenzeneacetic Acid 4-(Ethylamino)-2-butyn-1-yl Ester Hydrochloride. Grades: > 95%. CAS No. 181647-12-1. Molecular formula: C20H27NO3.HCl. Mole weight: 365.9.
Revaprazan HCl
Revaprazan is an acid pump antagonist. It can reduce gastric acid secretion which is used for the treatment of gastritis. Synonyms: 4-(3,4-Dihydro-1-methyl-2(1H)-isoquinolinyl)-N-(4-fluorophenyl)-5,6-dimethyl-2-pyrimidinamine Hydrochloride; 5,6-Dimethyl-2-(4-fluorophenylamino)-4-(1-methyl- 1,2,3,4-tetrahydroisoquinolin-2-yl)pyrimidine hydrochloride; Revaprazan Hydrochloride; SB 641257 Hydrochloride; SB 641257A; YH 1885. Grades: > 95%. CAS No. 178307-42-1. Molecular formula: C22H23N4F·HCl. Mole weight: 398.9041632.
Sodium lignosulfonate (lignosulfonic acid, sodium salt) is used in the food industry as a de-foaming agent for paper production and in adhesives for items that come in contact with food. It has preservative properties and is used as an ingredient in animal feeds. It is also used for construction, ceramics, mineral powder, chemical industry, textile industry (leather), metallurgical industry, petroleum industry, fire-retardant materials, rubber vulcanization, organic polymerization. Uses: Dispersant for concrete additives plastifying additive for bricks and ceramics tanning agents deflocculant bonding agent for fiberboards binding agent for molding of pellets, carbon black, fertilizers, activated carbon, foundry molds dust reduction agent during spraying for non-asphalted roads and dispersion in the agricultural domain. Group: Polymers. Alternative Names: ahr2438b; banirexn; betz402; dispergatorreax; dispergatorufoxane; lignosite458; lignosite854; lignosold10. CAS No. 8061-51-6. Product ID: disodium; (2R)-3-(2-hydroxy-3-methoxyphenyl)-2-[2-methoxy-4-(3-sulfonatopropyl)phenoxy]propane-1-sulfonate. Molecular formula: 534.5g/mol. Mole weight: C20H24Na2O10S2. COC1=CC=CC (=C1O)CC (CS (=O) (=O)[O-])OC2=C (C=C (C=C2)CCCS (=O) (=O)[O-])OC. [Na+]. [Na+]. InChI=1S/C20H26O10S2. 2Na/c1-28-18-7-3-6-15 (20 (18)21)12-16 (13-32 (25, 26)27)30-17-9-8-14 (11-19 (17)29-2)5-4-10-31 (22, 23)24; ; /h3, 6-9, 11, 16, 21H, 4-5, 10, 12-13H2, 1
Soybean oil
Soybean oil. Synonyms: Best One Soya;Bionatrol;CAP 18;CAP 18 (oil);CT 7000;Destiny HC;Fats and Glyceridic oils, soybean;HY 3050. CAS No. 8001-22-7. Pack Sizes: 250 mL in poly bottle. Product ID: CDC10-0079. Category: Antioxidant Cosmetic Chemicals. Product Keywords: Cosmetic Ingredients; Antioxidant Cosmetic Chemicals; Soybean oil; CDC10-0079; 8001-22-7; Best One Soya; Bionatrol; CAP 18; CAP 18 (oil); CT 7000; Destiny HC; Fats and Glyceridic oils, soybean; HY 3050; 232-274-4; MFCD00132356; 8001-22-7. Purity: 0.99. Color: Colorless to Yellow. EC Number: 232-274-4. Physical State: Oil. Quality Level: 200. Storage: 2-8°C. Application: It may be used as a crude source for triglycerides and other lipids. Soybean oil is a potential raw material in oxygenated fatty acid production. It may be used in the synthesis of epoxidized-soybean oil (ESO). Density: 0.917 g/mL at 25 °C(lit.). Product Description: Soybean oil (SBO) is a vegetable oil widely used as biodegradable lubricant. It increases left ventricular contractility associated myosin ATPase and sarcoplasmic reticulum calcium pump (SERCA2a) in isolated hearts from rats. SBO is shown to reduce both total and non-HDL serum cholesterol and triglycerides induced by atherogenic diet in rats. It may be transesterified to biodiesel using CaO as a solid base catalyst. It may also be transesterified to biodiesel using methanol and ethanol.
SR121566A
SR121566A, a non-peptide Glycoprotein IIb/IIIa (GP IIb-IIIa) antagonist, has been shown to block platelet aggregation induced by a wide variety of agonists including HIT serum/heparin, reduced in a dose-dependent manner the HIT serum/heparin-induced, platelet mediated expression and release of the above mentioned proteins. Synonyms: 3-[[1-(carboxymethyl)piperidin-4-yl]-[4-(4-methanehydrazonoylphenyl)-1,3-thiazol-2-yl]amino]propanoic acid; CTK0H1193; 1-Piperidineaceticacid, 4-[[4-[4-(aminoiminomethyl)phenyl]-2-thiazolyl](2-carboxyethyl)amino]-. CAS No. 180144-61-0. Molecular formula: C20H25N5O4S. Mole weight: 431.51.
Tacrolimus Impurity 6
Tacrolimus Impurity 6 is an impurity of Tacrolimus, which is a calcineurin inhibitor used as an immunosuppressant after organ transplantation to reduce the activity of the patient's immune system, thereby reducing the risk of organ rejection. Synonyms: Pyrido[2,1-c][1,4]oxaazacyclodocosine-19-carboxylic acid, 1, 3, 4, 5, 6, 7, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 22, 23, 24, 25, 25a-docosahydro-5, 15, 19-trihydroxy-3-[(1E)-2-[(1R, 3R, 4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-1, 7, 20-trioxo-8-(2-propen-1-yl)-, (3S, 4R, 5S, 8R, 9E, 12S, 14S, 15R, 16S, 18R, 25aS)-; (3S, 4R, 5S, 8R, 9E, 12S, 14S, 15R, 16S, 18R, 25aS)-1, 3, 4, 5, 6, 7, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 22, 23, 24, 25, 25a-Docosahydro-5, 15, 19-trihydroxy-3-[(1E)-2-[(1R, 3R, 4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-1, 7, 20-trioxo-8-(2-propen-1-yl)pyrido[2, 1-c][1, 4]oxaazacyclodocosine-19-carboxylic acid; Tacrolimus α-hydroxy acid; Tacrolimus hydroxy acid. Grades: >95%. CAS No. 1700657-83-5. Molecular formula: C44H71NO13. Mole weight: 822.06.
Tribehenin
Tribehenin is the triglyceride of behenic (C22) acid. Very soft and amorphous (non-crystalline) wax and can be used to modify the properties of other waxes by softening structure and reducing crystallinity and rigidity. Melting point: 57 - 62°C (135-144F). Uses: Stick products, deodorants, lip balms, pomades, foundations, creams, lotions. Group: Glycerides. Alternative Names: Propane-1,2,3-triyl tridocosanoate. CAS No. 18641-57-1. Molecular formula: C69H134O6. Mole weight: 1059.8. Appearance: Solid. Purity: 95%+. IUPACName: 2,3-Di(docosanoyloxy)propyl docosanoate. Canonical SMILES: CCCCCCCCCCCCCCCCCCCCCC (=O)OCC (COC (=O)CCCCCCCCCCCCCCCCCCCCC)OC (=O)CCCCCCCCCCCCCCCCCCCCC. Density: 0.899±0.06 g/cm³. Catalog: ACM18641571.
Trihexyltetradecylphosphonium bis(2,4,4-trimethylpentyl)phosphinate is a phosphonium-based ionic liquid. It can be prepared by reacting trihexyl(tetradecyl)-phosphonium chloride with bis(2,4,4-trimethylpentyl)phosphinic acid in the presence of a base. Uses: Metal plating, electropolishing, metal reprocessing, phase transfer media, batteries fuel cells, nanomaterials, industrial solvents, nuclear fuel red waste, enzymatic catalysis, lubricants heat transfer and solar energy conversion. Group: Electrolytes. Alternative Names: Tetradecyltrihexylphosphoniumbis(2, 4, 4-trimethylpentyl)phosphinate. CAS No. 465527-59-7. Product ID: bis(2,4,4-trimethylpentyl)phosphinate; trihexyl(tetradecyl)phosphanium. Molecular formula: 773.27. Mole weight: Linear Formula [CH3(CH2)5]3P[N(SO2CF3)2](CH2)13CH3. CCCCCCCCCCCCCC[P+] (CCCCCC) (CCCCCC)CCCCCC. CC (CC (C) (C)C)CP (=O) (CC (C)CC (C) (C)C)[O-]. 1S / C32H68P. C16H35O2P / c1-5-9-13-17-18-19-20-21-22-23-24-28- 32-33 (29-25-14-10-6-2, 30-26-15-11-7-3) 31-27-16-12-8-4; 1-13 (9-15 (3, 4) 5) 11-19 (17, 18) 12-14 (2) 10-16 (6, 7) 8 / h5-32H2, 1-4H3; 13-14H, 9-12H2, 1-8H3, (H, 17, 18) / q + 1; / p-1. ZKQLVOZSJHOZBL-UHFFFAOYSA-M. ≥90.0%.
very-long-chain 3-oxoacyl-CoA synthase
This is the first component of the elongase, a microsomal protein complex responsible for extending palmitoyl-CoA and stearoyl-CoA (and modified forms thereof) to very-long-chain acyl CoAs. Multiple forms exist with differing preferences for the substrate, and thus the specific form expressed determines the local composition of very-long-chain fatty acids. For example, the FAE1 form from the plant Arabidopsis thaliana accepts only 16 and 18 carbon substrates, with oleoyl-CoA (18:1) being the preferred substrate, while CER6 from the same plant prefers substrates with chain length of C22 to C32. cf. EC 1.1.1.330, very-long-chain 3-oxoacyl-CoA reductase, EC 4.2.1.134, very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase, and EC 1.3.1.93, very-long-chain enoyl-CoA reductase. Group: Enzymes. Synonyms: very-long-chain 3-ketoacyl-CoA synthase; very-long-chain β-ketoacyl-CoA . Enzyme Commission Number: EC 2.3.1.199. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2142; very-long-chain 3-oxoacyl-CoA synthase; EC 2.3.1.199; very-long-chain 3-ketoacyl-CoA synthase; very-long-chain β-ketoacyl-CoA synthase; condensing enzyme (ambiguous); CUT1 (gene name); CER6 (gene name); FAE1 (gene name); KCS (gene name); ELO (gene name). Cat No: EXWM-2142.