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| Product | Description | |
|---|---|---|
| Acid Red 260 | Acid Dyes. Alternative Names: Acid Red 260;C.I. Acid red 260. CAS No. 12239-07-5. Catalog: ACM12239075. |  |
| 1,2,3-trimethylimidazolium trifluoromethanesulfonate | Metal Plating, Electropolishing, Metal Reprocessing, Phase transfer media, Batteries Fuel Cells, Nanomaterials, Industrial Solvents, Nuclear Fuel Red Waste, Enzymatic Catalysis, Lubricants Heat Transfer and Solar Energy Conversion. Group: Heterocyclic organic compound. Alternative Names: 1,2,3-Trimethylimidazolium trifluoromethanesulfonate, Trifluoromethanesulfonic acid 1,2,3-Trimethylimidazolium salt, 05942_FLUKA, CTK8F2856, AG-L-62869, 439286-64-3. CAS No. 439286-64-3. Molecular formula: C7H11F3N2O3S. Mole weight: 260.23. Purity: 98% min. IUPACName: trifluoromethanesulfonate;1,2,3-trimethylimidazol-1-ium. Canonical SMILES: CC1=[N+](C=CN1C)C. C(F)(F)(F)S(=O)(=O)[O-]. Catalog: ACM439286643. | |
| 1-Butyl-3-methylimidazolium Hydrogen Sulfate | 1-Butyl-3-methylimidazolium hydrogen sulfate is an acidic ionic liquid. [BMIM][HSO4] can be used as an additive to accelerate current efficiency, lower power consumption, and enhance the surface morphology during the electrodeposition of zinc from acidic sulfate solutions. The combination of sodium nitrate and [BMIM][HSO4] can be used as a nitrating agent for the selective nitration of phenols to afford its corresponding nitro derivatives. Uses: Metal plating, electropolishing, metal reprocessing, phase transfer media, batteries fuel cells, nanomaterials, industrial solvents, nuclear fuel red waste, enzymatic catalysis, lubricants heat transfer and solar energy conversion. Group: Electrolytesbattery materials. Alternative Names: BMIMHSO4. CAS No. 262297-13-2. Product ID: 1-butyl-3-methylimidazol-3-ium; hydrogen sulfate. Molecular formula: 236.29. Mole weight: C8H16N2O4S. CCCCN1C=C[N+](=C1)C.OS(=O)(=O)[O-]. 1S/C8H15N2. H2O4S/c1-3-4-5-10-7-6-9(2)8-10; 1-5(2, 3)4/h6-8H, 3-5H2, 1-2H3; (H2, 1, 2, 3, 4)/q+1; /p-1. KXCVJPJCRAEILX-UHFFFAOYSA-M. >97.0%(HPLC)(N). |  |
| 1-Butyl-3-methylimidazolium Hydrogen Sulfate | 1-Butyl-3-methylimidazolium hydrogen sulfate is an acidic ionic liquid. [BMIM][HSO4] can be used as an additive to accelerate current efficiency, lower power consumption, and enhance the surface morphology during the electrodeposition of zinc from acidic sulfate solutions. The combination of sodium nitrate and [BMIM][HSO4] can be used as a nitrating agent for the selective nitration of phenols to afford its corresponding nitro derivatives. Uses: Metal plating, electropolishing, metal reprocessing, phase transfer media, batteries fuel cells, nanomaterials, industrial solvents, nuclear fuel red waste, enzymatic catalysis, lubricants heat transfer and solar energy conversion. Group: Imidazolium ionic liquids. Alternative Names: BMIMHSO4. CAS No. 262297-13-2. Molecular formula: C8H16N2O4S. Mole weight: 236.29. Appearance: Colorless to Red to Green clear liquid. Purity: >97.0%(HPLC)(N). IUPACName: 1-butyl-3-methylimidazol-3-ium;hydrogen sulfate. Canonical SMILES: CCCCN1C=C[N+](=C1)C.OS(=O)(=O)[O-]. Catalog: ACM262297132. | |
| 2-[[1-[ (Z) - (4-Oxo-2-thioxo-5-thiazolidinylidene) methyl]-2-naphthalenyl]oxy]-acetic Acid | 2-[[1-[ (Z) - (4-Oxo-2-thioxo-5-thiazolidinylidene) methyl]-2-naphthalenyl]oxy]-acetic Acid is used in biological activities in the preparation and aldose reductase inhibitory activity of a new series of 5-[[2- (ω -carboxyalkoxy) aryl]methylene]-4-oxo-2-thioxothiazolidine derivatives. Group: Biochemicals. Grades: Highly Purified. CAS No. 260784-21-2. Pack Sizes: 100mg, 1g. Molecular Formula: C16H11NO4S2, Molecular Weight: 345.39. US Biological Life Sciences. |  Worldwide |
| 2-[3-(Diethylamino)-6-diethylazaniumylidenexanthen-9-yl]-5-sulfobenzenesulfonate | Heterocyclic Organic Compound. Alternative Names: Sulforhodamine B, Lissamine rhodamine B, Sulforhodamine B, acid form, 2609-88-3, Xanthylium, 3,6-bis(diethylamino)-9-(2,4-disulfophenyl)-, inner salt, 3520-42-1, Xanthylium, 3,6-bis(diethylamino)-9-(2,4-disulfophenyl)-, hydroxide, inner salt, Kayaku Acid Rhodamine BH, AC1L22RY, Food Color Red No. 106, 341738_ALDRICH, AC1Q6X20, 341738_SIAL, 3520-42-1 (hydrochloride salt), EINECS 220-025-2, ST50826411, ST51006819, 40378A, Hydrogen 3,6-bis(diethylamino)-9-(2,4-disulphonatophenyl)xanthylium, 2-(6-DIETHYLAMINO-3-DIETHYLAZANIUMYLIDENE-XANTHEN-9-YL)-5-SULFO-BENZENESULFONATE. CAS No. 10090-50-3. Molecular formula: C27H30N2O7S2. Mole weight: 558.666 g/mol. Purity: 0.96. IUPACName: 2-[3-(diethylamino)-6-diethylazaniumylidenexanthen-9-yl]-5-sulfobenzenesulfonate. Canonical SMILES: CCN (CC)C1=CC2=C (C=C1)C (=C3C=CC (=[N+] (CC)CC)C=C3O2)C4=C (C=C (C=C4)S (=O) (=O)O)S (=O) (=O)[O-]. ECNumber: 220-025-2. Catalog: ACM10090503. | |
| (2R,4S)-4-Amino-2-ethyl-6-trifluoromethyl-3,4-dihydro-2H-quinoline-1-carboxylic Acid Ethyl Ester | (2R,4S)-4-Amino-2-ethyl-6-trifluoromethyl-3,4-dihydro-2H-quinoline-1-carboxylic Acid Ethyl Ester is derived from 4- (Trifluoromethyl) aniline (T791050), which is a 4-substituted aniline derivative, exert special hematotoxicity on the red blood cells and induce leukocytosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 261947-64-2. Pack Sizes: 5mg, 10mg. Molecular Formula: C15H19F3N2O2, Molecular Weight: 316.32. US Biological Life Sciences. | Worldwide |
| Acid red 1 | Acid red 1. Group: Polymers. Product ID: disodium; 5-acetamido-4-hydroxy-3-phenyldiazenylnaphthalene-2,7-disulfonate. Molecular formula: 509.4g/mol. Mole weight: C18H13N3Na2O8S2. CC (=O)NC1=C2C (=CC (=C1)S (=O) (=O)[O-])C=C (C (=C2O)N=NC3=CC=CC=C3)S (=O) (=O)[O-]. [Na+]. [Na+]. InChI=1S/C18H15N3O8S2. 2Na/c1-10 (22)19-14-9-13 (30 (24, 25)26)7-11-8-15 (31 (27, 28)29)17 (18 (23)16 (11)14)21-20-12-5-3-2-4-6-12; ; /h2-9, 23H, 1H3, (H, 19, 22) (H, 24, 25, 26) (H, 27, 28, 29); ; /q; 2*+1/p-2. WXLFIFHRGFOVCD-UHFFFAOYSA-L. | |
| Acid Red 118 | Acid Red 118 is a synthetic dye that falls under the Acid Dye class. Acid Red 118, also known as C.I. Acid Red 118 or Acid Red MTR, is a specific dye within the Acid Dye category. Uses: Acid dyes are water-soluble anionic dyes commonly used for dyeing protein fibers such as silk, wool, and nylon, as well as other materials like leather and synthetic fibers. Group: Acid dyes. Alternative Names: C.I. Acid red 118;Acid red 118 (C.I. 26410);Red GW. CAS No. 12217-35-5. Molecular formula: C25H24N4O6S2. Mole weight: 540.619. Appearance: Powder. Purity: 0.95. IUPACName: 6-amino-5-[[3-[ethyl(phenyl)sulfamoyl]-4-methylphenyl]diazenyl]-4-hydroxynaphthalene-2-sulfonic acid. Canonical SMILES: CCN (C1=CC=CC=C1)S (=O) (=O)C2=C (C=CC (=C2)N=NC3=C (C=CC4=CC (=CC (=C43)O)S (=O) (=O)O)N)C. Density: 1.5±0.1 g/mL. Catalog: ACM12217355. | |
| Acid Red 18 | Acid Red 18. Synonyms: New Coccine, Acid Red 18, Ponceau 4 R. CAS No. 2611-82-7. Pack Sizes: Bottomless glass bottle. Contents are inside inserted fused cone. Product ID: CDC10-0146. Molecular formula: C20H11N2O10S3Na3. Category: Cosmetic Color Additives. Product Keywords: Cosmetic Ingredients; Cosmetic Color Additives; Acid Red 18; CDC10-0146; 2611-82-7; C20H11N2O10S3Na3; New Coccine, Acid Red 18, Ponceau 4 R; 220-036-2; MFCD00004084; 2611-82-7. Purity: ≥98.0% (HPLC). Color: Bordeaux to brown. EC Number: 220-036-2. Physical State: Powder. Solubility: DMSO (Slightly, Heated, Sonicated), Methanol (Slightly, Heated), Water (Slightly. Quality Level: 100. Storage: Inert atmosphere,Room Temperature. Application: Ponceau 4R was used in the determination of contents of several additives in different non-alcoholic beverages using HPLC. It was used in understanding the genotoxicity of colorants. It was also used in preparing a falsified drink in the analysis of methanol-ethanol mixture using biosensors amperometric system. Melting Point: >300°C. Product Description: Ponceau 4R is a synthetic red azo dye and is used as a food colorant. It is used in range of alcoholic and non-alcoholic beverages, food stuffs, preserved fruits etc. It exists as trisodium-2-hydroxy-1-(4-sulfonato-1-naphthylazo)-6,8-naphthalenedisulfonate. |  |
| Acridine Orange Stain | Acridine Orange Stain is a fluorescent nucleic acid binding dye which interacts with both DNA and RNA. When bound to DNA, it emits green fluorescence (Em=525 nm) and when bound to RNA, it emits red fluorescence (Em=~650 nm). Group: Biochemicals. Grades: Highly Purified. CAS No. 494-38-2. Pack Sizes: 1g, 2.5g. Molecular Formula: C17H19N3, Molecular Weight: 265.35. US Biological Life Sciences. | Worldwide |
| Alisol B 23-Acetate | Alisol B 23-acetate (23-Acetylalismol B), a natural triterpenoid, produces protective effects against EE-induced cholestasis, due to FXR-mediated gene regulation.IC50 Value:Target: Anti-hepatotoxic natural product.In vitro: Alisol-B 23-acetate has an effect on FXR activation in a dose-dependent manner using luciferase reporter assay in HepG2 cells.In vivo: In alisol B 23-acetate-treated mice, the changes in transporters and enzymes, as well as ameliorative liver histology were abrogated by FXR antagonist guggulsterone. Alisol B 23-acetate treatment in a dose-dependent manner resulted in protection against hepatotoxicity induced by CCl4via FXR activation. Through FXR activation, alisol B 23-acetate promoted hepatocyte proliferation via an induction in hepatic levels of FoxM1b, Cyclin D1 and Cyclin B1. Alisol B 23-acetate also reduced hepatic bile acids through a decrease in hepatic uptake transporter Ntcp, bile acid synthetic enzymes Cyp7a1, Cyp8b1, and an increase in efflux transporter Bsep, Mrp2 expression. In addition, alisol B 23-acetate induced the expression of STAT3 phosphorylation, and STAT3 target genes Bcl-xl and SOCS3, resulting in decreased hepatocyte apoptosis. Group: Inhibitors. CAS No. 26575-95-1. Molecular formula: C32H50O5. Mole weight: 514.8. Appearance: White powder. Purity: 0.98. IUPACName: [1-(3,3-dimethyloxiran-2-yl)-3-[(8S,10S,11S,14R)-11-hydroxy-4,4,8,10,14-pentamethyl-3-oxo-1,2,5,6,7,9,11,12,15 | |
| ARN14974 | ARN14974 is a benzoxazolone carboxamide inhibitor of acid ceramidase with IC50 of 79 nM. It inhibits acid ceramidase activity, reduces levels of sphingosine and dihydroceramide, and increases levels of ceramide in SW403 adenocarcinoma cells and RAW 264.7 murine macrophages when used at concentrations ranging from 0.1 to 20 mM. Synonyms: Acid Ceramidase Inhibitor 17a; ARN-14974; ARN 14974; Acid Ceramidase Inhibitor 17a. Grades: ≥95%. CAS No. 1644158-57-5. Molecular formula: C24H21FN2O3. Mole weight: 404.4. |  |
| Atorvastatin Acetonide t-Butyl Ester Side Chain (4R,6S)-Isomer | Atorvastatin Acetonide t-Butyl Ester Side Chain (4R,6S)-Isomer is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Synonyms: tert-butyl 2-((4R,6S)-6-(cyanomethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate; (4R,6S)-6-(Cyanomethyl)-2,2-dimethyl--1,3-dioxane-4-acetic Acid tert-Butyl Ester; (4R-trans)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester. CAS No. 196085-84-4. Molecular formula: C14H23NO4. Mole weight: 269.34. | |
| β-Nicotinamide-Adenine Dinucleotide Phosphate, Reduced | β-Nicotinamide adenine dinucleotide 2?-phosphate (NADP+) and β-Nicotinamide adenine dinucleotide 2?-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. The NADP+/NADPH redox pair facilitates electron transfer in anabolic reactions such as lipid and cholesterol biosynthesis and fatty acyl chain elongation. Group: Coenzymes. Synonyms: β-Nicotinamide-Adenine Dinucleotide Phosphate, Reduced; 2646-71-16; β-NADPH. CAS No. 2646-71-16. Purity: Determined by decrease in absorbance at 340 nm on enzymatic reduction with GR*at pH 10.0 (> 95%) *GR = Glutathion reductase (yeast) (EC 1.6.4.2.). β-NADPH. Mole weight: 833.35. Storage: Keep tightly stoppered in the dark below 5°C. Moisture will reduce the purity. For prolonged storage, keep below-20°C. Unstable in acids, but relatively stable at pH 10-11. β-Nicotinamide-Adenine Dinucleotide Phosphate, Reduced; 2646-71-16; β-NADPH. Cat No: NATE-0787. |  |
| b-Nicotinamide Adenine Dinucleotide Phosphate, reduced form, tetrasodium salt ( β-NADPH) | One of the biologically active forms of nicotinic acid. Differs from NAD by an additional phosphate group at the 2-position of the adenosine moiety. Serves as a coenzyme of hydrogenases and dehydrogenases. Present in living cells primarily in the reduced form (NADPH) and is involved in synthetic reactions. Group: Biochemicals. Alternative Names: 2'-(Dihydrogen Phosphate) 5'-(Trihydrogen Pyrophosphate) adenosine 5'5'-Ester 1,4-Dihydro-1- β -D-ribofuranosyl nicotinamide Tetrasodium Salt Hydrate; β-NADPH; 2?-NADPH Hydrate; Coenzyme II Reduced Tetrasodium Salt Hydrate; Triphosphopyridine Nucleotide Reduced Tetrasodium Salt Hydrate; Dihydronicotinamide Adenine Dinucleotide Phosphate Tetrasodium Salt Hydrate. Grades: Highly Purified. CAS No. 2646-71-1. Pack Sizes: 100mg, 250mg, 500mg, 1g. Molecular Formula: C??H??N?Na?O??P?; xH?O, Molecular Weight: 833.35. US Biological Life Sciences. | Worldwide |
| Boc-L-valine N-methoxy-N-methyl amide | An α-Amino Weinreb amide. Reduced by LiAlH4 to give the corresponding Boc-amino acid aldehyde. Synonyms: Boc-L-Val-N(OCH3)CH3; (S)-2-(Boc-amino)-N-methoxy-N,3-dimethylbutanamide; Boc-L-Leucine N,O-Dimethylhydroxamide. Grades: ≥ 98 % (HPLC, Chiral purity). CAS No. 87694-52-8. Molecular formula: C12H24N2O4. Mole weight: 260.30. | |
| Calcium N5-methyltetrahydrofolate | Calcium N5-methyltetrahydrofolate is a metabolite of folic acid. It was shown to inhibit photosensitization reactions and strand breaks in DNA, and reduce total serum homocysteine level in orthotopic liver transplant recipients. Synonyms: Calcium methyltetrahydrofolate; NSC 173328; NSC-173328; NSC173328. Grades: >98%. CAS No. 26560-38-3. Molecular formula: C20H23CaN7O6. Mole weight: 497.52. | |
| Carbomer | Carbomers are white-colored, fluffy, acidic, hygroscopic powders with a characteristic slight odor. A granular carbomer is also available (Carbopol 71G). Synonyms: Acrypol; Acritamer; acrylic acid polymer; carbomera; Carbopol; carboxy polymethylene; polyacrylic acid; carboxyvinyl polymer; Pemulen; Tego Carbomer. CAS No. 9003-1-4. Product ID: PE-0469. Category: Bioadhesive Material; Controlled-release Agents; Emulsifying Agents; Emulsion Stabilizer; rheology modifier; Stabilizing Agents; Suspending Agents; Tablet Binder. Product Keywords: Suspending Agents; Emulsifier Excipients; Binder Excipients; ; PE-0469; Carbomer; Bioadhesive Material; Controlled-release Agents; Emulsifying Agents; Emulsion Stabilizer; rheology modifier; Stabilizing Agents; Suspending Agents; Tablet Binder; ; 9003-01-4. UNII: 9G2MAD7J6W. Chemical Name: Carbomer. Grade: Pharmceutical Excipients. Administration route: Oral; ophthalmic, rectal, topical, transdermal ; vaginal. Dosage Form: Oral suspensions, tablets; ophthalmic, rectal, topical, transdermal preparations; vaginal suppositories. Stability and Storage Conditions: Carbomers are stable, hygroscopic materials that may be heated at temperatures for up to 2 hours without affecting their thickening efficiency. However, exposure to excessive temperatures can result in discoloration and reduced stability. Complete decomposition occurs with heating for 30 minutes at 260°C. Dry powder forms of carbomer | |
| Carbomer 934 | Carbomer 934. Synonyms: Acritamer; acrylic acid polymer; Carbopol; carboxy polymethylene, polyacrylic acid; carboxyvinyl polymer; Pemulen; Ultrez. CAS No. 9003-1-4. Product ID: PE-0310. Molecular formula: (C3H4O2)n. Category: Suspending Agents; Thickener. Product Keywords: Excipients for Liquid Dosage Form; Suspending Agents; PE-0310; Carbomer 934; Suspending Agents; Thickener; (C3H4O2)n; 9003-01-4. UNII: Z135WT9208. Chemical Name: Cross-linked polyacrylic resin. Grade: Pharmceutical Excipients. Administration route: Oral administration; Rectum; Vagina; Local administration. Dosage Form: Oral suspensions and tablets, ophthalmic preparations, rectal preparations and topical preparations. Stability and Storage Conditions: Carbomer is a stable and hygroscopic substance that does not affect its thickening when heated at 104°C for 2 hours. However, exposure to excessive temperatures can reduce discoloration and stability. It is completely decomposed by heating at 260°C for 30 minutes. Dry powdery carbomer does not grow mildew. In contrast, microbes grow well in preservative-free aqueous dispersions. Therefore, preservatives such as 0.1%(W/V) of chlorocresol, 0.18% (W/V) of hydroxyphenylene methyl, 0.02%(W/V) of hydroxyphenylene propyl, or 0.1%(W/V) of thiomersal should be added. The addition of certain bacteriostatic agents, such as benzalammonium chloride or sodium benzoate, at high concentrations (0.1%W/V) caused turbidity | |
| Carbomer 940 | Carbomer 940. Synonyms: Acritamer; acrylic acid polymer; Carbopol; carboxy polymethylene, polyacrylic acid; carboxyvinyl polymer; Pemulen; Ultrez. CAS No. 9003-1-4. Product ID: PE-0637. Molecular formula: (C3H4O2)n. Category: Suspending Agents; Thickener. Product Keywords: Excipients for Liquid Dosage Form; Suspending Agents; PE-0637; Carbomer 940; Suspending Agents; Thickener; (C3H4O2)n; 9003-01-4. UNII: 4Q93RCW27E. Chemical Name: Cross-linked polyacrylic resin. Grade: Pharmceutical Excipients. Administration route: Topical; Ophthalmic; Transdermal. Dosage Form: Oral suspensions and tablets, ophthalmic preparations, rectal preparations and topical preparations. Stability and Storage Conditions: Carbomer is a stable and hygroscopic substance that does not affect its thickening when heated at 104°C for 2 hours. However, exposure to excessive temperatures can reduce discoloration and stability. It is completely decomposed by heating at 260°C for 30 minutes. Dry powdery carbomer does not grow mildew. In contrast, microbes grow well in preservative-free aqueous dispersions. Therefore, preservatives such as 0.1%(W/V) of chlorocresol, 0.18% (W/V) of hydroxyphenylene methyl, 0.02%(W/V) of hydroxyphenylene propyl, or 0.1%(W/V) of thiomersal should be added. The addition of certain bacteriostatic agents, such as benzalammonium chloride or sodium benzoate, at high concentrations (0.1%W/V) caused turbidity and decreased viscosity | |
| Carbomer 974P | Carbomer 974P. Synonyms: Acritamer; acrylic acid polymer; Carbopol; carboxy polymethylene, polyacrylic acid; carboxyvinyl polymer; Pemulen; Ultrez. CAS No. 2594-32-2. Product ID: PE-0638. Molecular formula: (C3H4O2)n. Category: Suspending Agents; Thickener. Product Keywords: Excipients for Liquid Dosage Form; Suspending Agents; PE-0638; Carbomer 974P; Suspending Agents; Thickener; (C3H4O2)n; 2594-32-2. UNII: NA. Chemical Name: Cross-linked polyacrylic resin. Grade: Pharmceutical Excipients. Administration route: Topical; Ophthalmic; Transdermal. Dosage Form: Oral suspensions and tablets, ophthalmic preparations, rectal preparations and topical preparations. Stability and Storage Conditions: Carbomer is a stable and hygroscopic substance that does not affect its thickening when heated at 104°C for 2 hours. However, exposure to excessive temperatures can reduce discoloration and stability. It is completely decomposed by heating at 260°C for 30 minutes. Dry powdery carbomer does not grow mildew. In contrast, microbes grow well in preservative-free aqueous dispersions. Therefore, preservatives such as 0.1%(W/V) of chlorocresol, 0.18% (W/V) of hydroxyphenylene methyl, 0.02%(W/V) of hydroxyphenylene propyl, or 0.1%(W/V) of thiomersal should be added. The addition of certain bacteriostatic agents, such as benzalammonium chloride or sodium benzoate, at high concentrations (0.1%W/V) caused turbidity and decreased viscosity of c | |
| Carbomer 980P | Carbomers are white-colored, fluffy, acidic, hygroscopic powders with a characteristic slight odor. A granular carbomer is also available (Carbopol 71G). CAS No. 139637-85-7. Product ID: PE-0470. Category: Carrier Excipients. Product Keywords: Pharmaceutical Excipients; Other Materials; Carbomer 980P; Carrier Excipients; Carrier Excipients; 139637-85-7; 139637-85-7. UNII: NA. Chemical Name: Carbomer 980. Grade: Pharmceutical Excipients. Administration route: Oral; ophthalmic, rectal, topical, transdermal. vaginal. Dosage Form: Oral suspensions, tablets; ophthalmic, rectal, topical, transdermal preparations. vaginal suppositories. Stability and Storage Conditions: Carbomers are stable, hygroscopic materials that may be heated at temperatures below 1048C for up to 2 hours without affecting their thickening efficiency. However, exposure to excessive temperatures can result in discoloration and reduced stability. Complete decomposition occurs with heating for 30 minutes at 260°C. Dry powder forms of carbomer do not support the growth of molds and fungi. In contrast, microorganisms grow well in unpreserved aqueous dispersions, and therefore an antimicrobial preservative such as 0.1% w/v chlorocresol, 0.18% w/v methylparaben-0.02% w/v propylparaben, or 0.1% w/v thimerosal should be added. The addition of certain antimicrobials, such as benzalkonium chloride or sodium benzoate, in high concentrations (0.1% w/v) can cause cl | |
| CGP 23996 | CGP 23996 is a non-reducible somatostatin analog. It can be used for autoradiography. Uses: Autoradiography. Synonyms: CGP 23996; CGP23996; CGP-23996. BDBM82467; 2-Deamino-L-Abu(1)-L-Lys-L-Asp(NH2)-L-Phe-L-Phe-L-Trp-L-Lys-L-Thr-L-Tyr-L-Thr-L-Ser-L-Abu(1)-OH;(14R,20S,23R,26R,29R,32R)-2,17-bis(4-aminobutyl)-5-(2-amino-2-oxoethyl)-8,11-dibenzyl-20,26-bis[(1S)-1-hydroxyethyl]-29-(hydroxymethyl)-23-[(4-hydroxyphenyl)methyl]-14-(1H-indol-3-ylmethyl)-3,6,9,12,15,18,21,24,27,30,38-undecaoxo-1,4,7,10,13,16,19,22,25,28,31-undecazacyclooctatriacontane-32-carboxylic acid. Grades: 98%. CAS No. 86170-12-9. Molecular formula: C73H99N15O18. Mole weight: 1474.66. | |
| CGS 35066 | CGS 35066 is a potent endothelin-converting enzyme (ECE) inhibitor with > 100-fold selectivity over neutral endopeptidase 24.11 (IC50 = 22 and 2300 nM, respectively). It blocks the hypertensive effects induced by big ET-1 in vitro and reduces the magnitude of cerebral vasospasm following subarachnoid hemorrhage (SAH). Synonyms: CGS 35066; CGS35066; CGS-35066; α-[(S)-(Phosphonomethyl)amino]-3-dibenzofuranpropanoic acid; (2S)-3-dibenzofuran-3-yl-2-(phosphonomethylamino)propanoic acid. Grades: ≥99% by HPLC. CAS No. 261619-50-5. Molecular formula: C16H16NO6P. Mole weight: 349.28. | |
| Cholecystokinin (26-33) (free acid) | Cholecystokinin (26-33) (CCK (26-33)) free acid is a cholecystokinin (CCK) fragment. Cholecystokinin (26-33) free acid can reduce food intake and gallbladder contraction [1]. Uses: Scientific research. Group: Peptides. Alternative Names: CCK (26-33) (free acid). CAS No. 103974-46-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3651. |  |
| cholest-4-en-3-one 26-monooxygenase [(25R)-3-oxocholest-4-en-26-oate forming] | This enzyme, found in several bacterial pathogens, is involved in degradation of the host cholesterol. It catalyses the hydroxylation of the C-26 carbon, followed by oxidation of the alcohol to the carboxylic acid via the aldehyde intermediate, initiating the degradation of the alkyl side-chain of cholesterol. The products are exclusively in the (25R) conformation. The enzyme also accepts cholesterol as a substrate. cf. EC 1.14.13.141, cholest-4-en-3-one 26-monooxygenase. The enzyme can receive electrons from ferredoxin reductase in vitro, its natural electron donor is not known yet. Group: Enzymes. Synonyms: CYP142. Enzyme Commission Number: EC 1.14.13.221. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0824; cholest-4-en-3-one 26-monooxygenase [(25R)-3-oxocholest-4-en-26-oate forming]; EC 1.14.13.221; CYP142. Cat No: EXWM-0824. | |
| cholest-4-en-3-one 26-monooxygenase [(25S)-3-oxocholest-4-en-26-oate forming] | This enzyme, found in several bacterial pathogens, is involved in degradation of the host's cholesterol. It catalyses the hydroxylation of the C-26 carbon, followed by oxidation of the alcohol to the carboxylic acid via the aldehyde intermediate, initiating the degradation of the alkyl side-chain of cholesterol. The products are exclusively in the (25S) configuration. It is a two-component system consisting of a P-450 (heme thiolate) oxygenase (Cyp125) and a ferredoxin reductase (most likely KshB, which is also a part of EC 1.14.13.142, 3-ketosteroid 9α-monooxygenase). The enzyme also accepts cholesterol as a substrate. cf. EC 1.14.13.221, cholest-4-en-3-one 27-monooxygenase. Group: Enzymes. Synonyms: CYP125; CYP125A1; cholest-4-en-3-one 27-monooxygenase (misleading); cholest-4-en-3-one,NADH:oxygen oxidoreductase (26-hydroxyl. Enzyme Commission Number: EC 1.14.13.141. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0741; cholest-4-en-3-one 26-monooxygenase [(25S)-3-oxocholest-4-en-26-oate forming]; EC 1.14.13.141; CYP125; CYP125A1; cholest-4-en-3-one 27-monooxygenase (misleading); cholest-4-en-3-one,NADH:oxygen oxidoreductase (26-hydroxylating); cholest-4-en-3-one 26-monooxygenase (ambiguous). Cat No: EXWM-0741. | |
| cholestanetriol 26-monooxygenase | This mitochondrial cytochrome P-450 enzyme requires adrenodoxin. It catalyses the first three sterol side chain oxidations in bile acid biosynthesis via the neutral (classic) pathway. Can also act on cholesterol, cholest-5-ene-3β,7α-diol, 7α-hydroxycholest-4-en-3-one, and 5β-cholestane-3α,7α-diol. The enzyme can also hydroxylate cholesterol at positions 24 and 25. The initial source of the electrons is NADPH, which transfers the electrons to the adrenodoxin via EC 1.18.1.6, adrenodoxin-NADP+ reductase. Group: Enzymes. Synonyms: 5β-cholestane-3α,7α,12α-triol 26-hydroxylase; 5β-cholestane-3α,7α,12α-triol hydroxylase; cholestanetriol 26-hydroxylase; sterol 27-hydroxylase; sterol 26-hydroxylase; cholesterol 27-hydroxyla. Enzyme Commission Number: EC 1.14.15.15. CAS No. 52227-77-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0940; cholestanetriol 26-monooxygenase; EC 1.14.15.15; 52227-77-7; 5β-cholestane-3α,7α,12α-triol 26-hydroxylase; 5β-cholestane-3α,7α,12α-triol hydroxylase; cholestanetriol 26-hydroxylase; sterol 27-hydroxylase; sterol 26-hydroxylase; cholesterol 27-hydroxylase; CYP27A; CYP27A1; cytochrome P450 27A1'. Cat No: EXWM-0940. | |
| D-Amino acid dehydrogenase, Recombinant | D-amino-acid dehydrogenase (EC 1.4.99.1) is a bacterial enzyme that catalyses the oxidation of D-amino acids into their corresponding oxoacids. It contains both flavin and nonheme iron as cofactors. The enzyme has a very broad specificity and can act on most D-amino acids. D-amino acid + H2O + acceptor <=> a 2-oxo acid + NH3 + reduced acceptor. This reaction is distinct from the oxidation reaction catalysed by D-amino acid oxidase that uses oxygen as a second substrate, as the dehydrogenase can use many different compounds as electron acceptors, with the physiological substrate being coenzyme Q. D-amino-acid dehydrogenase is used in enzyme assays to measure substrate specificity of D-amino acids, such as DauA. Applications: D-amino-acid dehydrogenase is a bacterial enzyme that catalyses the oxidation of d-amino acids into their corresponding oxoacids. it contains flavin and nonheme iron as cofactors and has a broad specificity thereby acting on most d-amino acids. Group: Enzymes. Synonyms: D-Amino acid dehydrogenase; EC 1.4.99.1; 37205-44-0. Enzyme Commission Number: EC 1.4.99.1. CAS No. 37205-44-0. D-Amino acid dehydrogenase. Activity: >26 U/g. Storage: Store at 2-8°C. Source: E. coli. D-Amino acid dehydrogenase; EC 1.4.99.1; 37205-44-0. Cat No: NATE-0825. | |
| DC 260126 | DC 260126 is a free fatty acid receptor 1 (FFA1/GPR40) antagonist that decreases intracellular Ca2+ levels and suppresses palmitic acid potentiated glucose-stimulated insulin secretion in Min6 pancreatic β cells in vitro. It was shown to lower serum insulin levels, improve insulin sensitivity and reduces the rate of apoptotic pancreatic β cells in obese diabetic (db/db) rats. Synonyms: DC 260126; DC260126; DC-260126; N-(4-Butylphenyl)-4-fluorobenzenesulfonamide. Grades: ≥98% by HPLC. CAS No. 346692-04-4. Molecular formula: C16H18FNO2S. Mole weight: 307.38. | |
| Dehydroanonaine | Dehydroanonaine is a dietary supplement that is used for the treatment of pain. It inhibits the activity of creatine kinase, which is an enzyme that breaks down adenosine triphosphate (ATP) to produce energy. Dehydroanonaine also inhibits acetate extract from fatty acids and has been shown to have an inhibitory effect on tyrosinase, an enzyme involved in the production of melanin. The effective dose for dehydroanonaine is not known. Dehydroanonaine can be used cosmetically by increasing the skin's elasticity and reducing wrinkles and age spots. Group: Other alkaloids. CAS No. 41679-82-7. Molecular formula: C17H13NO2. Mole weight: 263.29 g/mol. Canonical SMILES: C1CNC2= CC3= CC= CC= C3C4= C2C1= CC5= C4OCO5. Catalog: ACM41679827. | |
| EBPC | EBPC is a potent and selective aldose reductase inhibitor. It is used to improve the cytotoxicity of anticancer reagents such as cisplatin and doxorubicin in HeLa cervical carcinoma cells via an increase in ERK activity. Synonyms: Ethyl 1-benzyl-3-hydroxy-2(5H)-oxopyrrole-4-carboxylate; 1-Benzyl-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylic acid ethyl ester; MFCD00179167; 1-benzyl-4-[ethoxy (hydroxy)methylidene]pyrrolidine-2, 3-dione. Grades: ≥99% by HPLC. CAS No. 4450-98-0. Molecular formula: C14H15NO4. Mole weight: 261.28. | |
| ethyl 2-(2-(3-hydroxyphenyl)thiazol-4-yl)acetate | An impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Synonyms: Febuxostat Impurity 61; 4-Thiazoleacetic acid, 2-(3-hydroxyphenyl)-, ethyl ester. CAS No. 171017-48-4. Molecular formula: C13H13NO3S. Mole weight: 263.31. | |
| Febuxostat Impurity 19 | An impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Synonyms: 5-Thiazolecarboxylic acid, 2-(2-hydroxyphenyl)-4-methyl-, ethyl ester. Grades: > 95%. CAS No. 118485-48-6. Molecular formula: C13H13NO3S. Mole weight: 263.32. | |
| Febuxostat Impurity 9 | An impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Synonyms: 2-(3-cyano-4-hydroxyphenyl)?-4-methyl- 5-Thiazolecarboxylic acid. Grades: > 95%. CAS No. 407582-48-3. Molecular formula: C12H8N2O3S. Mole weight: 260.27. | |
| Food Red No. 102 | Food Red No. 102. Group: Biochemicals. Alternative Names: 7-Hydroxy-8-[2-(4-sulfo-1-naphthalenyl)diazenyl]-1,3-naphthalenedisulfonic Acid Trisodium Salt; C.I. Acid Red 18; Cochineal Red 4R; New Coccine; Coccin Red; Takaoka Brilliant Scarlet 3R; Triacid Ponceau 4R; Triacid Scarlet 3R; Trisodium 1-(4-sulfo-1-naphthylazo)-2-naphthol-6,8-disulfonate; Vicoacid Scarlet 3R; Victoria Scarlet 3R; Victoria Scarlet Red. Grades: Highly Purified. CAS No. 2611-82-7. Pack Sizes: 5g. Molecular Formula: C20H11N2Na3O10S3, Molecular Weight: 604.47. US Biological Life Sciences. | Worldwide |
| Glutathione S-Transferase from E.coli, Recombinant | Glutathione S-transferases (GSTs), previously known as ligandins, comprise a family of eukaryotic and prokaryotic phase II metabolic isozymes best known for their ability to catalyze the conjugation of the reduced form of glutathione (GSH) to xenobiotic substrates for the purpose of detoxification. The GST family consists of three superfamilies:the cytosolic, mitochondrial, and microsomal--also known as MAPEG--proteins. Members of the GST superfamily are extremely diverse in amino acid sequence, and a large fraction of the sequences deposited in public databases are of unknown function. The Enzyme Function Initiative (EFI) is using GSTs as a model superfamily to iden...ferase. Mole weight: 26kDa. Activity: >20 units/mg. Stability: Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. Form: Sterile Filtered clear solution in Phosphate Buffered Saline pH 7.4. Source: E.coli. Species: E.coli. Glutathione S-transferases; GSTs; GST; Glutathione S-alkenetransferase; Glutathione S-alkyltransferase; Glutathione S-aralkyltransferase; Glutathione S-aryltransferase; Glutathione S-epoxidetransferase; RX:Glutathione R-transferase; EC 2.5.1.18; 50812-37-8. Cat No: NATE-1945. | |
| Glutathione S-Transferase, Recombinant | Glutathione S-transferases (GSTs), previously known as ligandins, comprise a family of eukaryotic and prokaryotic phase II metabolic isozymes best known for their ability to catalyze the conjugation of the reduced form of glutathione (GSH) to xenobiotic substrates for the purpose of detoxification. The GST family consists of three superfamilies:the cytosolic, mitochondrial, and microsomalalso known as MAPEGproteins. Members of the GST superfamily are extremely diverse in amino acid sequence, and a large fraction of the sequences deposited in public databases are of unknown function. The Enzyme Function Initiative (EFI) is using GSTs as a model superfamily to identify new...erase; Glutathione S-aryltransferase; Glutathione S-epoxidetransferase; RX:Glutathione R-transferase; EC 2.5.1.18; 50812-37-8. Enzyme Commission Number: EC 2.5.1.18. Purity: >90% (SDS-PAGE test). Mole weight: About 26kDa (SDS-PAGE detection). Activity: 30 u/mg. Appearance: White powder, lyophilized or colorless liquid. Storage: 4°C, store at -20°C for long-term preservation. Form: Freeze dried powder. Glutathione S-transferases; GSTs; GST; Glutathione S-alkenetransferase; Glutathione S-alkyltransferase; Glutathione S-aralkyltransferase; Glutathione S-aryltransferase; Glutathione S-epoxidetransferase; RX:Glutathione R-transferase; EC 2.5.1.18; 50812-37-8. Cat No: NATE-1141. | |
| Hexaamminecobalt(III) chloride | As reagent for pyrophosphoric acid, for the estimation of phosphate. Group: Metal & ceramic materials. Alternative Names: Hexaamminecobalt(III) trichloride. CAS No. 10534-89-1. Molecular formula: Cl3CoH18N6. Mole weight: 267.47. Appearance: Wine-red or brownish-orange-red solid. Purity: 99%+. IUPACName: Azane;cobalt(3+);trichloride. Canonical SMILES: N.N.N.N.N.N.[Cl-].[Cl-].[Cl-].[Co+3]. Density: 1.71 g/mL at 25 °C (lit.). ECNumber: 234-103-9. Catalog: ACM10534891-2. | |
| Humic acid sodium salt | Sodium humate is made from natural lignite or leonardite, appears in black powder, granule and flake, it has been widely used in animal feed additive, aquiculture, industry as well as agriculture. Uses: Humic acid sodium salt is suitable reagent used to study the hygroscopic growth of solid aerosol particles consisting of mixtures of ammonium sulfate, adipic acid and humic acid mixtures. it is suitable reagent used to study the phase transitions and hygroscopic growth of humic acid aerosols by fourier transform infra-red (ftir) spectroscopy and tandem differential mobility analysis (tdma). Group: Heterocyclic organic compound. CAS No. 68131-04-4. Molecular formula: C9H8Na2O4. Mole weight: 226.13696. ECNumber: 268-608-0. Catalog: ACM68131044. | |
| Iron(iII)ammonium citrate green | Heterocyclic Organic Compound. Alternative Names: Ammonium iron(III) citrate; Ammonium Ferric Citrate; Citric acid iron ammonium; Ironandammoniumcit-rate; Amonium Iron(III) Citrate Supplement; IRON AMMONIUM CITRATE; Ammoniumironcitrate; AmmoniumFerricCitrateUsp; Ferricammoniumcitrae; Ferric. CAS No. 1185-57-6. Molecular formula: C6H8FeNO7. Mole weight: 261.975. Appearance: Ferric ammonium citrate is a yellowish brown to red solid with a faint odor of ammonia. Purity: 0.96. IUPACName: Ammonium ferric citrate. Density: 1.8 g/cm³ (20ºC). Catalog: ACM1185576. | |
| KR-32568 | KR-32568 is a sodium-hydrogen exchanger isoform-1 (NHE-1) inhibitor (IC50 = 230 nM). KR-32568 inhibited NHE-1-mediated rabbit platelet swelling induced by intracellular acidification. It reduced myocardial infarct size in an anesthetized rat model. Synonyms: [5-(2-Methyl-5-fluorophenyl)furan-2-ylcarbonyl]guanidine. Grades: ≥98%. CAS No. 852146-73-7. Molecular formula: C13H12FN3O2. Mole weight: 261.3. | |
| L-365,260 | L-365,260 is a nonpeptide cholecystokinin receptor 2 (CCK2/CCKB) antagonist. It selectively binds to gastrin and CCK2 sites to reduce basal acid secretion, and prevent gastrointestinal damage in models of peptic ulcer disease. Synonyms: N-[(3R)-2,3-Dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]-N'-(3-methylphenyl)urea. Grades: ≥99% by HPLC. CAS No. 118101-09-0. Molecular formula: C24H22N4O2. Mole weight: 398.46. | |
| Loxoprofen Related Compound 2 (Mixture of Diastereomers) | An impurity of Loxoprofen, a non-selective nonsteroidal anti-inflammatory drug (NSAID) that has been effective in reducing atherosclerosis in mice by reducing inflammation. Synonyms: 2- (4- ( (1-hydroxy-2-oxocyclopentyl) methyl) phenyl) propanoic acid. Grades: > 95%. CAS No. 1091621-62-3. Molecular formula: C15H18O4. Mole weight: 262.31. | |
| Lycopene | Lycopene, in the concentration used, is not toxic and also its health benefits in adipose tissue may play a role against obesity-related complications. Lycopene in tomato puree has decreased indicating an indirect effect on lycopene stability caused by high concentration of hydrogen peroxide and the activation of peroxidase enzymes leading to the reduction of ascorbic acid and its regenerative action towards lycopene. Besides, Lycopene protected β-carotene against isomerization during reactions with singlet oxygen and radicals. These findings can explain the pattern of carotenoid isomers analyzed in fruits and vegetables, where lycopene containing samples showed higher (all-E)/(9Z)-β-carotene ratios, and also in in vivo samples such as human blood plasma. Lycopene can be used as pigment in food processing, and is also used as raw material of antioxidant health food. Uses: Ingredient of health care products. Synonyms: ψ,ψ-Carotene; all-trans-Lycopene; Lyco Vit; Lycopene 7; Lycored; NSC 407322; Redivivo; trans-Lycopene; (all-E)-2,6,10,14,19,23,27,31-Octamethyl-2,6,8,10,12,14,16,18,20,22,24,26,30-dotriacontatridecaene. Grades: 96%. CAS No. 502-65-8. Molecular formula: C40H56. Mole weight: 536.87. | |
| Methyl red | Methyl red (2-(N,N-dimethyl-4-aminophenyl) azobenzenecarboxylic acid), also called C.I. Acid Red 2, is an indicator dye that turns red in acidic solutions. It is an azo dye, and is a dark red crystalline powder. Methyl red is a pH indicator; it is red in pH under 4.4, yellow in pH over 6.2, and orange in between, with a pKa of 5.1. Murexide and methyl red are investigated as promising enhancers of sonochemical destruction of chlorinated hydrocarbon pollutants. Methyl red is classed by the IARC in group 3 - unclassified as to carcinogenic potential in humans. Group: Heterocyclic organic compound. Alternative Names: 2-[4- (dimethylamino)phenylazo]benzoic acid;4-dimethylaminoazobenzene-2-carboxylic acid;Methyl Red,indicator;2-(4-Dimethylaminophenylazo)benzoic acid;4-Dimethylaminoazobenzene-2-carboxylic acid. CAS No. 493-52-7. Molecular formula: C15H15N3O2. Mole weight: 269.3. Appearance: Red crystalline powder. Purity: Purity >97%. IUPACName: 2-[4- (dimethylamino) phenyl]diazenylbenzoic acid. Canonical SMILES: CN (C)C1=CC=C (C=C1)N=NC2=CC=CC=C2C (=O)O. Density: 0.839 g/mL at 25ºC. ECNumber: 207-776-1. Catalog: ACM493527. | |
| MS39 | MS39 (compound 6) is a PROTAC targeting EGFR. MS39 is composed of PROTAC target protein ligand N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(3-(piperazin-1-yl)propoxy)quinazolin-4-amine (HY-W109039) (red part), E3 ligase ligand (S,R,S)-AHPC (HY-125845) (blue part) and PROTAC Linker Undecanedioic acid (HY-W014125) (black part), among which the conjugate of E3 ubiquitin ligase ligand + Linker is (S,R,S)-AHPC-CO-C9-acid (HY-139345). MS39 reduces the expression of EGFR and downstream signaling in HCC-827 and H3255 cells. MS39 inhibits the proliferation of H3255 cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2675490-92-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-157581. | |
| Nafazatrom | Nafazatrom is a pyrazolinone derivative. It increases endogenous prostacyclin (PGI2) and has potential antimetastatic activities. It is used an antithrombotic drug that increases PGI2 levels. It inhibits the key prostaglandin catabolic enzyme, 15-hydroxyprostaglandin dehydrogenase, which prolongs the biological half-life of PGI2 and prevents intravascular coagulation. It also serves as a reducing cofactor with the hydroperoxidase moiety of cyclooxygenase and accelerates the conversion of arachidonic acid into precursors of PGI2. It is a lipoxygenase inhibitor, reduces stimulated Prolactin secretion. It also reduces the incidence of accompanying arrhythmias in myocardial injuries. Uses: Nafazatrom is used an antithrombotic drug. Synonyms: 2,4-Dihydro-5-methyl-2-[2-(2-naphthalenyloxy)ethyl]-3H-pyrazol-3-one; Bay-g-6575; BAY g 6575; 3-methyl-1-(2-(naphthalen-2-yloxy)ethyl)-1H-pyrazol-5(4H)-one. Grades: 98%. CAS No. 59040-30-1. Molecular formula: C16H16N2O2. Mole weight: 268.32. | |
| OAT-889 | OAT-889 is a dual inhibitor of acidic mammalian chitinase (AMCase) and chitotriosidase-1 (CHIT1) (hAMCase IC50 = 9 nM;hCHIT1 IC50 = 26 nM), which has the potential to treat asthma. OAT-889 reduced the number of infiltrating leukocytes in bronchoalveolar lavage fluid (BALF) in an acute mouse model of lung inflammation, as well as decreased mRNA of proinflammatory cytokines, such as interleukin-13, interleukin-1 and Muc5AC in lung tissue. Uses: The treatment of asthma. Synonyms: OAT 889; OAT889. | |
| Octadecylamine | Octadecylamine is used in biological studies for the formation of ion pairing as alternative to improve encapsulation and stability and to reduce skin irritation of retinoic acid loaded in solid lipid nanoparticles. Group: Biochemicals. Grades: Highly Purified. CAS No. 124-30-1. Pack Sizes: 5g, 25g. Molecular Formula: C18H39N, Molecular Weight: 269.51. US Biological Life Sciences. | Worldwide |
| Pectate Lyase from Clostridium acetobutylicum, Recombinant | Pectate lyase (EC 4.2.2.2) is an enzyme involved in the maceration and soft rotting of plant tissue. Pectate lyase is responsible for the eliminative cleavage of pectate, yielding oligosaccharides with 4-deoxy-α-D-mann-4-enuronosyl groups at their non-reducing ends. The protein is maximally expressed late in pollen development. It has been suggested that the pollen expression of pectate lyase genes might relate to a requirement for pectin degradation during pollen tube growth. This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on polysaccharides. Group: Enzymes. Synonyms: (1->4)-alpha-D-galacturonan lyase; polygalact...eight: 26628.7 Da. Activity: 3.2 U/mg. Storage: Store at 4°C (shipped at room temperature). Form: Supplied in 3.2 M ammonium sulphate. Source: Clostridium acetobutylicum ATCC 824. (1->4)-alpha-D-galacturonan lyase; polygalacturonic transeliminase; pectic acid transeliminase; polygalacturonate lyase; endopectin methyltranseliminase; pectate transeliminase; endogalacturonate transeliminase; pectic acid lyase; pectic lyase; alpha-1,4-D-endopolygalacturonic acid lyase; PGA lyase; PPase-N; endo-alpha-1,4-polygalacturonic acid lyase; polygalacturonic acid lyase; pectin trans-eliminase; Polygalacturonic acid trans-eliminase; Pectate lyase; EC 4.2.2.2. Cat No: NATE-1223. | |
| PG490-88 | PG490-88 is a semisynthetic derivative of the novel compound PG490 (triptolide) purified from a Chinese herb. It has been shown to prolong acute allograft survival in multiple experimental organ transplant models. However, the effect of PG490-88 on prevention of acute and chronic renal allograft rejection has not been determined. Kidneys of ACI or F344 rats were transplanted into bilaterally nephrectomized LEW recipients as the acute or chronic allograft rejection models, respectively. Treatment of LEW recipients with PG490-88 significantly prolonged ACI kidney graft survival in a dose-dependent manner when compared with the untreated allograft controls. LEW recipients of F344 kidney grafts who received PG490-88 for 90 days with a brief course of low-dose FK506 showed normal serum creatinine levels and markedly reduced histological changes of chronic rejection at day 90 after transplantation. These results suggest that PG490-88 significantly prolongs kidney allograft survival in an acute rejection model and prevents chronic allograft rejection in rats. Synonyms: Omtriptolide; PG490 88; YM 262; YM-262; YM262; 4-{[(3bS, 4aS, 5aR, 6R, 6aS, 7aS, 7bS, 8aS, 8bS)-6a-Isopropyl-8b-methyl-1-oxo-1, 3, 3b, 4, 4a, 6, 6a, 7a, 7b, 8b, 9, 10-dodecahydrotrisoxireno[6, 7:8a, 9:4b, 5]phenanthro[1, 2-c]furan-6-yl]oxy}-4-oxobutanoic acid. Grades: ≥98%. CAS No. 195883-06-8. Molecular formula: C24H28O9. Mole weight: 460.47. | |
| Phosphonomycin Calcium salt | It is produced by the strain of Str. fradiae NRRL-3417, Str. viridchromogenes NRRL-3413. It's an antibiotic that contains phosphorus. It has anti-gram positive bacterial and negative bacterial activity, inorganic phosphorus and sodium chloride can reduce its activity. It has protective effect on mice infected with Staphylococcus aureus, Salmonella typhi and Salmonella paratyphi B by oral administration. Synonyms: (-)-Phosphonomycin Calcium salt; Calcium fosfomycin; fosfomycin calcium; Fosmicin; Phosphonic acid, [(2R,3S)-3-methyloxiranyl]-, calcium salt (1:1); Phosphonic acid, (1,2-epoxypropyl)-, calcium salt (1:1), (1R,2S)-(-)-; Phosphonic acid, P-[(2R,3S)-3-methyl-2-oxiranyl]-, calcium salt (1:1); Phosphonic acid, (3-methyloxiranyl)-, calcium salt (1:1), (2R-cis)-. Grades: 98%. CAS No. 26016-98-8. Molecular formula: C3H5O4P.Ca. Mole weight: 176.12. | |
| Ponceau 4R | Ponceau 4R is a synthetic colorant that can be used for food coloring. Ponceau 4R is a strawberry red azo dye that can be used in a variety of foods, usually synthesized from aromatic hydrocarbons, and is stable to light, heat, and acids [1] [2]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Acid Red 18; New Coccine. CAS No. 2611-82-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-D0193. | |
| Propyl Red | Red dye, 98%. Synonyms: 2-(4-Dipropylaminophenylazo)benzoic acid. CAS No. 2641-1-2. Pack Sizes: 1g, 5g. Product ID: FR-2354. M.P. 173-175. Mole weight: 327.43. |  Frinton Laboratories |
| Resolvin D1 | Resolvin D1 (RvD1), an endogenous pro-resolving mediator of inflammation, is derived from omega-3 docosahexaenoic acid during the resolution phase of acute inflammation. Resolvin D1 blocks proinflammatory neutrophil migration by regulating actin polymerization, reduces TNF-α - mediated inflammation in macrophages, and enhances phagocytosis of apoptotic cells by macrophages [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: RvD1. CAS No. 872993-05-0. Pack Sizes: 25 μg (265.6 μM * 250 μL in Ethanol). Product ID: HY-125527. | |
| Revaprazan Impurity A | An impurity of Revaprazan. Revaprazan is an acid pump antagonist. It can reduce gastric acid secretion which is used for the treatment of gastritis. Grades: > 95%. Molecular formula: C14H17FN4. Mole weight: 260.32. | |
| Rhodium (III) chloride trihydrate | Rhodium(III) chloride is often used in synthetic chemistry as a hydrogenation catalyst. Rhodium(III) chloride is also used to make transition metal complexes, some of which are used as reagents in the decarbonylation dehydration reactions of fatty acids to alkenes. Uses: Catalyst in conjunction with "pybox" for the asymmetric hydrosilylation of ketones. c-c bond forming reactions. Group: Metal & ceramic materials. Alternative Names: RhodiumchloridehydrateRh;Rhodium chloride hydrate;Rhodium chloride (RhCl3),hydrate;Rhodium (III) Chloride Trihydrate; Rhodium(III)chloridehydrate(38-Rh). CAS No. 20765-98-4. Molecular formula: Cl3H6O3Rh. Mole weight: 263.31. Appearance: Red-brown to dark brown crystalline powder. Purity: Rh ≥39.0%. ECNumber: 233-165-4. Catalog: ACM20765984. | |
| Rose Bengal, 90%, indicator | Rose Bengal, 90%, indicator. Group: Xanthene dyes. Alternative Names: Acid Red 94; Rosa bengala sodica (131 I) [INN-Spanish]; C20H2Cl4I4Na2O5; disodium 4,5,6,7-tetrachloro-2',4',5',7'-tetraiodo-3-oxospiro[2-benzo[b]furan-1,9'-xanthene]-3',6'-diolate; C.I. 45440; Food Red Color No. 105, sodium salt; FT-0621857; Xantryl; Rose bengal disodium salt; R105 sodium. CAS No. 632-69-9. Product ID: disodium; 4,5,6,7-tetrachloro-2',4',5',7'-tetraiodo-3-oxospiro[2-benzofuran-1,9'-xanthene]-3',6'-diolate. Molecular formula: 1017.628g/mol. Mole weight: C20H2Cl4I4Na2O5. C1=C2C (=C (C (=C1I)[O-])I)OC3=C (C (=C (C=C3C24C5=C (C (=C (C (=C5Cl)Cl)Cl)Cl)C (=O)O4)I)[O-])I. [Na+]. [Na+]. InChI=1S/C20H4Cl4I4O5. 2Na/c21-9-7-8 (10 (22)12 (24)11 (9)23)20 (33-19 (7)31)3-1-5 (25)15 (29)13 (27)17 (3)32-18-4 (20)2-6 (26)16 (30)14 (18)28; ; /h1-2, 29-30H; ; /q; 2*+1/p-2. KCQREHTWEUECQT-UHFFFAOYSA-L. | |
| Sodium Indanylcarbinicillin | Sodium Indanylcarbinicillin, a penicillin-derived, has been used as a β-lactam antibiotic which inhibits the synthesis of peptidoglycan, a key component of the bacterial cell wall. It also has been shown to reduce blood pressure in mammals. Uses: Anti-bacterial agents. Synonyms: (2S,5R,6R)-6-[[3-[(2,3-Dihydro-1H-inden-5-yl)oxy]-1,3-dioxo-2-phenylpropyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid Sodium Salt; (2S,5R,6R)-6-[[3-[(2,3-dihydro-1H-inden-5-yl)oxy]-1,3-dioxo-2-phenylpropyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid Monosodium Salt; [2S-(2α,5α,6β)]-6-[[3-[(2,3-Dihydro-1H-inden-5-yl)oxy]-1,3-dioxo-2-phenylpropyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid Monosodium Salt; CP 15464-2; Carbenicillin Indanyl Sodium; Carindacillin Sodium; Carindapen; GU-Pen; Geocillin; Indanyl Carbenicillin Sodium Salt; Monosodium Indanyl Carbenicillin; Sodium 5-indanylcarbenicillin; Sodium Indanylcarbenicillin; 4800-94-6 (Carbenicillin Disodium). Grades: >98%. CAS No. 26605-69-6. Molecular formula: C26H25N2NaO6S. Mole weight: 516.54. | |
| Sodium Lignosulfonate | Sodium lignosulfonate (lignosulfonic acid, sodium salt) is used in the food industry as a de-foaming agent for paper production and in adhesives for items that come in contact with food. It has preservative properties and is used as an ingredient in animal feeds. It is also used for construction, ceramics, mineral powder, chemical industry, textile industry (leather), metallurgical industry, petroleum industry, fire-retardant materials, rubber vulcanization, organic polymerization. Uses: Dispersant for concrete additives plastifying additive for bricks and ceramics tanning agents deflocculant bonding agent for fiberboards binding agent for molding of pellets, carbon black, fertilizers, activated carbon, foundry molds dust reduction agent during spraying for non-asphalted roads and dispersion in the agricultural domain. Group: Polymers. Alternative Names: ahr2438b; banirexn; betz402; dispergatorreax; dispergatorufoxane; lignosite458; lignosite854; lignosold10. CAS No. 8061-51-6. Product ID: disodium; (2R)-3-(2-hydroxy-3-methoxyphenyl)-2-[2-methoxy-4-(3-sulfonatopropyl)phenoxy]propane-1-sulfonate. Molecular formula: 534.5g/mol. Mole weight: C20H24Na2O10S2. COC1=CC=CC (=C1O)CC (CS (=O) (=O)[O-])OC2=C (C=C (C=C2)CCCS (=O) (=O)[O-])OC. [Na+]. [Na+]. InChI=1S/C20H26O10S2. 2Na/c1-28-18-7-3-6-15 (20 (18)21)12-16 (13-32 (25, 26)27)30-17-9-8-14 (11-19 (17)29-2)5-4-10-31 (22, 23)24; ; /h3, 6-9, 11, 16, 21H, 4-5, 10, 12-13H2, 1 | |
| tert-butyl 2-((4R,6R)-6-(cyanomethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate | tert-butyl 2-((4R,6R)-6-(cyanomethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Synonyms: tert-Butyl (4R,6R)-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate; (4R,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester; 6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic acid 1,1-Dimethylethyl Ester, (4R-cis)-. CAS No. 125971-94-0. Molecular formula: C14H23NO4. Mole weight: 269.34. | |
| tert-butyl 2-((4R,6S)-6-(hydroxymethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate | tert-butyl 2-((4R,6S)-6-(hydroxymethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Synonyms: tert-butyl 2,4-dideoxy-3,5-O-(1-methylethylidene)-D-erythro-hexonate; 2,4-Dideoxy-3,5-O-(1-methylethylidene)-D-erythro-hexonic Acid 1,1-Dimethylethyl Ester; (4R,6S)-6-Hydroxymethyl-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester; 2-[(4R,6S)-6-(Hydroxymethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetic Acid tert-Butyl Ester. CAS No. 124655-09-0. Molecular formula: C13H24O5. Mole weight: 260.33. | |
| Tracid Red 2bs | Acid Red 266 is a synthetic azo dye that is extensively used in various industries, such as textiles, food, cosmetics, and pharmaceuticals. It is a water-soluble dye with a reddish-brown color and is known to have excellent color fastness properties. However, its extensive usage has raised concerns about its potential impact on human health and the environment. Uses: Acid red 266 has been widely used in scientific research as a model compound to study the fate and behavior of azo dyes in the environment. it has been used to investigate the adsorption, degradation, and biodegradation of azo dyes in various environmental matrices, such as soils, sediments, and water. acid red 266 has also been used as a staining agent in histological and cytological studies, where it is used to differentiate between different types of cells and tissues. Group: Acid dyes. Alternative Names: Acid red 266. CAS No. 57741-47-6. Molecular formula: C17H10ClF3N3NaO4S. Mole weight: 467.782. Appearance: Powder. IUPACName: sodium;6-amino-5-[[4-chloro-2-(trifluoromethyl)phenyl]diazenyl]-4-hydroxynaphthalene-2-sulfonate. Canonical SMILES: C1=CC (=C (C2=C (C=C (C=C21)S (=O) (=O)[O-])O)N=NC3=C (C=C (C=C3)Cl)C (F) (F)F)N. [Na+]. Density: 1.68 g/mL at 20°C. Catalog: ACM57741476. | |
| Ulodesine | Ulodesine, also known as BCX4208, is a purine nucleoside phosphorylase (PNP) inhibitor in development as a once-daily oral, chronic treatment for gout. Ulodesine is currently being developed by Biocryst. Ulodesine acts upstream of xanthine oxidase in the purine metabolism pathway to reduce the production of serum uric acid (sUA). Ulodesine has an IC(50) of 0.5 nM to PNP. BCX-4208 is currently undergoing early clinical investigation in psoriasis and gout. Group: Inhibitors. Alternative Names: BCX4208, BCX 4208, BCX-4208, Ulodesine, DADMe-immucillin H. CAS No. 548486-59-5. Molecular formula: C12H16N4O3. Mole weight: 264.28. Appearance: Solid powder. Purity: >98%. IUPACName: 7-(((3R,4R)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-1-yl)methyl)-3H-pyrrolo[3,2-d]pyrimidin-4(5H)-one. Canonical SMILES: O=C1C (NC=C2CN3C[C@H] (O)[C@@H] (CO)C3)=C2N=CN1. Catalog: ACM548486595. | |
| Ulodesine | Ulodesine, also known as BCX4208, is a purine nucleoside phosphorylase (PNP) inhibitor in development as a once-daily oral, chronic treatment for gout. Ulodesine is currently being developed by Biocryst. Ulodesine acts upstream of xanthine oxidase in the purine metabolism pathway to reduce the production of serum uric acid (sUA). Ulodesine has an IC(50) of 0.5 nM to PNP. BCX-4208 is currently undergoing early clinical investigation in psoriasis and gout. (last update: ). Synonyms: BCX4208; BCX 4208; BCX-4208; DADMe-immucillin H. CAS No. 548486-59-5. Molecular formula: C12H16N4O3. Mole weight: 264.28. | |
| URB937 | URB937 is a potent, peripheral fatty acid amide hydrolase (FAAH) inhibitor with IC50 value of 26.8 nM. It was shown to reduce prostaglandin E2-induced bladder overactivity and hyperactivity of bladder mechano-afferent nerve fibers in rats. Synonyms: URB-937; URB 937; [3-(3-carbamoylphenyl)-4-hydroxyphenyl] N-cyclohexylcarbamate. Grades: ≥95%. CAS No. 1357160-72-5. Molecular formula: C20H22N2O4. Mole weight: 354.4. | |
| Acid red 18 | Reddish powder or granules. Group: Polymers. Product ID: trisodium; 7-hydroxy-8-[(4-sulfonatonaphthalen-1-yl)diazenyl]naphthalene-1,3-disulfonate. Molecular formula: 604.5g/mol. Mole weight: C20H11N2Na3O10S3;C20H11N2Na3O10S3. C1=CC=C2C (=C1)C (=CC=C2S (=O) (=O)[O-])N=NC3=C (C=CC4=CC (=CC (=C43)S (=O) (=O)[O-])S (=O) (=O)[O-])O. [Na+]. [Na+]. [Na+]. InChI=1S/C20H14N2O10S3. 3Na/c23-16-7-5-11-9-12 (33 (24, 25)26)10-18 (35 (30, 31)32)19 (11)20 (16)22-21-15-6-8-17 (34 (27, 28)29)14-4-2-1-3-13 (14)15; ; ; /h1-10, 23H, (H, 24, 25, 26) (H, 27, 28, 29) (H, 30, 31, 32); ; ; /q; 3*+1/p-3. SWGJCIMEBVHMTA-UHFFFAOYSA-K. | |
| Mevastatin Hydroxy Acid t-Butylamine Salt | A HMG-CoA reductase inhibitor. It has been shown to be effective in reducing cholesterol synthesis in vivo, and thereby in lowering cholesterol levels in blood. Group: Biochemicals. Alternative Names: ( βR, δR, 1S, 2S, 8S, 8aR)-1, 2, 6, 7, 8, 8a-Hexahydro- β,δ-dihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoate 2-Methyl-2-propanamine. Grades: Highly Purified. CAS No. 262285-80-3. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
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