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| Product | Description | |
|---|---|---|
| Acid Red 52 | Dyes & Metabolites; Dyes & Metabolites. Uses: For analytical and research use. Group: Reagents. Alternative Names: Orient Water Red 27, Brilliant Superlan Rhodamine B, Colocid Rhodamine BH, Aizen Food Red No. 106, Daiwa Red 106WB, Kayacyl Rhodamine FB, Indacid Rhodamine B, Sandolan Rhodamine E-B 400, Amido Rhodamine B, Acid Rose B, Duasyn Acid Rhodamine B 01, Nylosan Rhodamine B, Kiton Red 620, Triacid Rhodamine B, Rhodamine Acid, [6-(Diethylamino)-9-(2,4-disulfophenyl)-3H-xanthen-3-ylidene]diethylammonium hydroxide inner salt sodium salt, Acid Red XB, Food Red No. 106, Colocid Rhodamine BN, Lissamine Rhodamine B 200, Conacid Red EB, Red 106, Hispacid Brilliant Pink B, Pacid Rhodamine ...ed 106, Lissamine Rhodamine B, Rhodamine 200S, Pro-Jet Red OAM, Rhodamine B, Kemacid Rhodamine B, Red no. 106, Brilliant Superlan Rhodamine 2B, Japan Red No. 106, Sulforhodamin B, C.I. 45100, Solar Rhodamine B, Kayaku Acid Rhodamine FB, Kiton Rhodamine B, Sulforhodamine B, 3,6-bis(Diethylamino)-9-(2,4-disulfophenyl)xanthylium inner salt sodium salt, Acid Red 52, Fenazo Pink XXB, Japan Red 106, Kiton Red S, Dyacid Red 4B, Ravi Acid Rhodamine B,3,6-Bis(diethylamino)-9-(2,4-disulfophenyl)xanthylium inner salt sodium salt (1:1), C.I. Acid Red 52, Duramine Rhodamine B, Acid Rhodamine, Phloxine rhodamine, Sandolan Rhodamine E-B. CAS No. 3520-42-1. IUPAC Name: sodium;4-[3,6-bis(diethylamino)xa |  |
| 2-alkenal reductase [NAD(P)+] | Highly specific for 4-hydroxynon-2-enal and non-2-enal. Alk-2-enals of shorter chain have lower affinities. Exhibits high activities also for alk-2-enones such as but-3-en-2-one and pent-3-en-2-one. Inactive with cyclohex-2-en-1-one and 12-oxophytodienoic acid. Involved in the detoxication of α,β-unsaturated aldehydes and ketones [cf. EC 1.3.1.102, 2-alkenal reductase (NADP+)]. Group: Enzymes. Synonyms: NAD(P)H-dependent alkenal/one oxidoreductase; NADPH:2-alkenal α,β-hydrogenase; 2-alkenal reductase. Enzyme Commission Number: EC 1.3.1.74. CAS No. 52227-95-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1343; 2-alkenal reductase [NAD(P)+]; EC 1.3.1.74; 52227-95-9; NAD(P)H-dependent alkenal/one oxidoreductase; NADPH:2-alkenal α,β-hydrogenase; 2-alkenal reductase. Cat No: EXWM-1343. |  |
| Acridine Orange Stain | Acridine Orange Stain is a fluorescent nucleic acid binding dye which interacts with both DNA and RNA. When bound to DNA, it emits green fluorescence (Em=525 nm) and when bound to RNA, it emits red fluorescence (Em=~650 nm). Group: Biochemicals. Grades: Highly Purified. CAS No. 494-38-2. Pack Sizes: 1g, 2.5g. Molecular Formula: C17H19N3, Molecular Weight: 265.35. US Biological Life Sciences. |  Worldwide |
| cholestanetriol 26-monooxygenase | This mitochondrial cytochrome P-450 enzyme requires adrenodoxin. It catalyses the first three sterol side chain oxidations in bile acid biosynthesis via the neutral (classic) pathway. Can also act on cholesterol, cholest-5-ene-3β,7α-diol, 7α-hydroxycholest-4-en-3-one, and 5β-cholestane-3α,7α-diol. The enzyme can also hydroxylate cholesterol at positions 24 and 25. The initial source of the electrons is NADPH, which transfers the electrons to the adrenodoxin via EC 1.18.1.6, adrenodoxin-NADP+ reductase. Group: Enzymes. Synonyms: 5β-cholestane-3α,7α,12α-triol 26-hydroxylase; 5β-cholestane-3α,7α,12α-triol hydroxylase; cholestanetriol 26-hydroxylase; sterol 27-hydroxylase; sterol 26-hydroxylase; cholesterol 27-hydroxyla. Enzyme Commission Number: EC 1.14.15.15. CAS No. 52227-77-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0940; cholestanetriol 26-monooxygenase; EC 1.14.15.15; 52227-77-7; 5β-cholestane-3α,7α,12α-triol 26-hydroxylase; 5β-cholestane-3α,7α,12α-triol hydroxylase; cholestanetriol 26-hydroxylase; sterol 27-hydroxylase; sterol 26-hydroxylase; cholesterol 27-hydroxylase; CYP27A; CYP27A1; cytochrome P450 27A1'. Cat No: EXWM-0940. | |
| Crocacin B | It is produced by the strain of Chondromyces crocatus sp. Cm c3. It has anti-yeast and filamentous fungal activity. It can inhibit mouse fibroblasts L929 (MIC is 0.2 ng). In the microsomes of the calf's heart, it can interrupt the bc1 segment of electronic transmission, causes redshift of 569nm peak in cytochrome B reduction spectrum. Synonyms: [[(2Z,5Z)-6-[[(2E,4E,6S,7S,8R,9S,10E)-7,9-Dimethoxy-3,6,8-trimethyl-1-oxo-11-phenyl-2,4,10-undecatrienyl]amino]-1-oxo-2,5-hexadienyl]amino]acetic acid; 2-[6-((2E,4E,10E)(6S,7S,9S,8R)-7,9-Dimethoxy-3,6,8-trimethyl-11-phenylundeca-2,4,10-trienoylamino)(2Z,5Z)hexa-2,5-dienoylamino]acetic acid. CAS No. 237425-37-5. Molecular formula: C30H40N2O6. Mole weight: 524.65. |  |
| Eosin Y disodium salt, dye content 85%, indicator | Anti Septic. Group: Acid dyes. Alternative Names: Eosine YB; Phlox Red Toner X-1354; MCULE-3311428648; Spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, 2',4',5',7'-tetrabromo-3',6'-dihydroxy-, sodium salt (1:2); CHEBI:52053; I14-18436; MFCD00036189; Eosine J; 7549-EP2277567A1; Certiqual Eosine. CAS No. 17372-87-1. Molecular formula: C20H6Br4Na2O5. Mole weight: 691.859g/mol. IUPACName: disodium;2-(2,4,5,7-tetrabromo-3-oxido-6-oxoxanthen-9-yl)benzoate. Canonical SMILES: C1=CC=C (C (=C1)C2=C3C=C (C (=O)C (=C3OC4=C (C (=C (C=C24)Br)[O-])Br)Br)Br)C (=O)[O-]. [Na+]. [Na+]. ECNumber: 241-409-6. Catalog: ACM17372871. |  |
| Ethidium homodimer | Ethidium homodimer (EthD-1) is a high-affinity fluorescent nucleic acid dye commonly used to stain mammals, bacteria, yeast, and fungi. Ethidium homodimer binds to DNA or RNA, enhancing fluorescence more than 30 times. The Ethidium homodimer has a strong positive charge, so it cannot cross cell membranes and stain living cells; But the Ethidium homodimer can cross the disordered region of the dead cell membrane to reach the nucleus and embed the DNA double strand to produce red fluorescence. Therefore, Ethidium homodimer is a relatively sensitive nucleic acid stain that can accurately detect nucleic acids in solution or in decomposing cells. Ethidium homodimer binds DNA, Ex/Em=528/617 nm [1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: EthD-1. CAS No. 61926-22-5. Pack Sizes: 500 μg; 1 mg. Product ID: HY-D0093. |  |
| Ganoderenic acid E | Ganoderenic acid E is a natural compound derived from Ganoderma lucidum that exhibits anticancer and anti-inflammatory properties. It has been shown to inhibit the growth of various cancer cells and reduce inflammation in experimental models. Grades: >98%. CAS No. 110241-23-1. Molecular formula: C30H40O8. Mole weight: 528.642. | |
| Gemcitabine elaidate | Gemcitabine elaidate (also known as CO-101; CP-4126) is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite deoxynucleoside analogue, with potential antineoplastic activity. Upon hydrolysis intracellularly by esterases, the prodrug gemcitabine is converted into the active metabolites difluorodeoxycytidine di- and tri-phosphate (dFdCDP and dFdCTP) by deoxycytidine kinase. dFdCDP inhibits ribonucleotide reductase, thereby decreasing the deoxynucleotide pool available for DNA synthesis; dFdCTP is incorporated into DNA, resulting in DNA strand termination and apoptosis. Due to its lipophilicity, gemcitabine 5'-elaidic acid ester exhibits an increased cellular uptake and accumulation, resulting in an increased conversion to active metabolites, compared to gemcitabine. In addition, this formulation of gemcitabine may be less susceptible to deamination and deactivation by deoxycytidine deaminase. Synonyms: CO-101; CO101; CO 101; CP-4126; CP4126; CP 4126. CAS No. 210829-30-4. Molecular formula: C27H43F2N3O5. Mole weight: 527.654. | |
| GW-1100 | A cell-permeable pyrimidinylmethyl-pyrimidinone compound that acts as potent, reversible and non-competitive GPR40 antagonist. Shown to significantly reverse glucose-induced insulin secretion potentiated by GW9508 and only partially reduce linoleic acid effect in MIN6 cells. Synonyms: GW 1100; GW-1100; GW1100. Grades: >98%. CAS No. 306974-70-9. Molecular formula: C27H25FN4O4S. Mole weight: 520.58. | |
| HZ52 | HZ52 is a novel reversible inhibitor of 5-lipoxygenase, blocking leukotriene synthesis with an IC50 value of 0.7 μM in intact human polymorphonuclear leukocytes. HZ52 was shown to prevent carrageenan-induced pleurisy accompanied by reduced LTB(4) levels and protected mice (10 mg·kg?¹, i.p.) against PAF-induced shock. Synonyms: HZ-52; HZ 52; 2-[4-Chloro-6-(4-phenylanilino)pyrimidin-2-yl]sulfanyloctanoic acid. Grades: ≥98%. CAS No. 1077626-51-7. Molecular formula: C24H26ClN3O2S. Mole weight: 456. | |
| L-Cysteine | L-Cysteine (Cysteine) is an orally active conditionally essential amino acid with hypoglycemic effects, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine promotes the proliferation and differentiation of neural stem cells via the CBS/H2S pathway. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans. L-Cysteine can be used as an anorectic agent [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Cysteine. CAS No. 52-90-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-Y0337. | |
| L-Cysteine hydrochloride | L-Cysteine hydrochloride is an orally active conditionally essential amino acid , which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine hydrochloride suppresses ghrelin and reduces appetite in rodents. L-Cysteine hydrochloride inhibits Aspergillus flavus growth and AFB synthesis by disrupting cell structure and antioxidant system balance. L-Cysteine hydrochloride enhances relaxant responses of rat aortic rings to NO and reduces responses to endothelium-derived relaxing factor (EDRF) [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 52-89-1. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-Y0337A. | |
| MK0533 | MK0533 is a novel selective peroxisome proliferator-activated receptor gamma modulator. It is used for the treatment of type 2 diabetes mellitus. It reduces potential to increase plasma and extracellular fluid volume. It showed diminished maximal activity in cell-based transcription activation assays and attenuated gene signatures in adipose tissue. Uses: Mk0533 is used for the treatment of type 2 diabetes mellitus. Synonyms: MK-0533; MK 0533; (R)-2-(3-(3-(4-methoxybenzoyl)-2-methyl-6-(trifluoromethoxy)-1H-indol-1-yl)phenoxy)butanoic acid. Grades: 98%. CAS No. 668455-28-5. Molecular formula: C28H24F3NO6. Mole weight: 527.50. | |
| Oxalic Acid | An impurity of oxaliplatin which is a coordination complex that is used in cancer chemotherapy. A reducing agent and its conjugate base, known as oxalate (C2O42?), is a useful chelating agent for metal cations. Group: Biochemicals. Alternative Names: Ethanedioic Acid; Aktisal; Aquisal; DeerClean; NSC 132055; NSC 151956; NSC 62774; NSC 76990; Ultraplast Activate S 52. Grades: Highly Purified. CAS No. 144-62-7. Pack Sizes: 2.5g. US Biological Life Sciences. | Worldwide |
| Pigment red 52:2 | Heterocyclic Organic Compound. Alternative Names: Pigment Red 52:2;Manganese, 4-[(4-chloro-5-methyl-2-sulfophenyl)azo]-3-hydroxy-2-naphthalenecarboxylic acid complex;Manganate(1-), 4-4-chloro-5-methyl-2-(sulfo-. kappa. O)phenylazo-. kappa. N1-3-(hydroxy-. kappa. O)-2-naphthalenecarboxylato(3-)-, hydrogen;BON. CAS No. 12238-31-2. Molecular formula: C18H11ClMnN2O6S. Mole weight: 473.75. Catalog: ACM12238312. | |
| Poly(acrylamide-co-acrylic acid) partial sodium salt | The hydrophilic polymer contains polar or charged functional groups, making it soluble in water. Uses: Thickening agent, binder, sizing agent, flocculating agent, crosslinker, filtering aid, lubricant, drag reduction and polymer recovery agent. Group: Hydrophilic polymerspolymers. CAS No. 62649-23-4. Pack Sizes: Packaging 250 g in poly bottle. Product ID: sodium; prop-2-enamide; prop-2-enoate; prop-2-enoic acid. Molecular formula: Mn 150,000 (Typical) Mw 520,000. Mole weight: C9H12NNaO5. [Na+]. NC(=O)C=C. OC(=O)C=C. [O-]C(=O)C=C. 1S/C3H5NO.2C3H4O2.Na/c3*1-2-3(4)5; /h2H, 1H2, (H2, 4, 5); 2*2H, 1H2, (H, 4, 5); /q; ; ; +1/p-1. DTBMFUOWAASNDB-UHFFFAOYSA-M. |  |
| Pranoprofen | Pranoprofen is a non-steroidal anti-inflammatory agent ( NSAID ) for the research of keratitis or other ophthalmology diseases. Pranoprofen inhibit COX-1 and COX-2 enzymes, thus blocking arachidonic acid converted to eicosanoids and reducing prostaglandins synthesis [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 52549-17-4. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B0336. | |
| Protoverine | Protoverine is a nitrogen-containing steroidal alkaloid that acts on the central nervous system. It has been shown to have electrophysiological effects, such as inhibition of acetylcholine release, and antihypertensive activity. Protoverine has also been shown to inhibit the growth of brain tumor cells in culture. Protoverine is reduced by borohydride and converted to tiglic acid, which inhibits Na channels in rat ventricular myocytes. The reduction of protoverine is temperature dependent and can be measured using titration calorimetry. Group: Other alkaloids. CAS No. 76-45-9. Molecular formula: C27H43NO9. Mole weight: 525.63 g/mol. Canonical SMILES: C[C@H]1CC[C@H]2[C@@] ([C@@H]3[C@@H] (CN2C1)[C@@H]4C[C@@]56[C@H] ([C@@]4 ([C@H] ([C@@H]3O)O)O)[C@@H] ([C@@H] ([C@H]7[C@@]5 (CC[C@@H] ([C@]7 (O6)O)O)C)O)O) (C)O. Catalog: ACM76459. | |
| Rosuvastatin Impurity 12 | An impurity of Rosuvastatin. Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Synonyms: SCHEMBL1021914; SCHEMBL1022804; 2-((4R,6S)-6-((E)-2-(4-(4-Fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetic acid; 894787-93-0. Grades: 95%. CAS No. 894787-93-0. Molecular formula: C25H32FN3O6S. Mole weight: 521.60. | |
| Salazinic acid | Salazinic acid is a depsidone lichen metabolite originally isolated from P. sulcata. It is active against B. cereus, B. subtilis, S. aureus, P. aeruginosa, S. typhimurium, C. albicans, and A. niger in vitro (MICs = 3.9-30.8 mM). Salazinic acid is also cytotoxic to MM98, A431, and HaCaT cells in crystal violet (EC50s = 159, 2,870, and 48 μM, respectively) and neutral red uptake assays (EC50s = 1,925, 1,913, and 907 μM, respectively). Synonyms: Salazinic acid; 521-39-1; SALAZIC ACID; NSC-87509; NSC87509. Grades: ≥95%. CAS No. 521-39-1. Molecular formula: C18H12O10. Mole weight: 388.28. | |
| SR 1903 | SR 1903 is an inverse agonist of retinoic acid receptor-related orphan receptor γ (RORγ) and an agonist of liver X receptor (LXR). It also binds to PPARγ without activity. It reduces blood glucose levels in a glucose tolerance test, serum levels of total cholesterol and LDL, body weight, and fat mass in a mouse model of high-fat diet-induced obesity. Synonyms: 1-[2'-Methyl-4'-[[4-(4-pyridylmethyl)-1-piperazinyl]methyl]-4-biphenylyl]-1-(trifluoromethyl)-2,2,2-trifluoroethanol. Grades: ≥98%. CAS No. 1414248-06-8. Molecular formula: C27H27F6N3O. Mole weight: 523.51. | |
| Streptonigrin (Bruneomycin, Nigrin, Rufocromomycin, Valacidin, Antibiotic RP 5278) | Streptonigrin is an unusual aminoquinone with broad biological activity against bacteria, fungi, nematodes, viruses and tumor cells. Streptonigrin acts as a bioreductive agent, highly dependent on interactions with metal ions, notably iron, and plays an important role in free radical production through redox cycling of NAD(P)H:quinone oxidoreductase (NQO1). Streptonigrin from Streptomyces flocculus is an aminoquinone antitumor antibiotic. Its antineoplastic activity requires reductive activation by Xanthine-converting enzymes. It induces apoptosis by a mechanism involving NF-κB. DNA cleavage reaction and chromosome damage by Streptonigrin are influenced by the nature of the metal ion present and dependent on the production of free radicals. Its antibiotic activity is iron-activated. Group: Biochemicals. Alternative Names: EC Number 223-501-8; 5278RP; AO 50165L302; Abbott Crystalline antibiotic; Bruneomycin; NSC 45383; NSC 56748; NSC 83950; Nigrin; Rufocromomycin; SN; STP; Streptonigran; Streptonigrin; 5-Amino-6-(7-amino-5,8-dihydro-6-methoxy-5,8-dioxo-2-quinolyl)-4-(2-hydroxy-3,4-dimethoxyphenyl)-3-methylpicolinic Acid; (4R)-5-Amino-6-(7-amino-5,8-dihydro-6-methoxy-5,8-dioxo-2-quinolinyl)-4-(2-hydroxy-3,4-dimethoxyphenyl)-3-methyl-2-pyridinecarboxylic Acid; (R)-Streptonigrin. Grades: Highly Purified. CAS No. 3930-19-6. Pack Sizes: 1mg. Molecular Formula: C??H??N?O?, Molecular Weight: 506.46. US Biological Life Sciences. | Worldwide |
| Sulforhodamine B Sodium Salt (C.I. 45100, Kiton Red S) | Fluorescent dye which uses laser-induced fluorescence for quantification of cellular proteins. Sulforhodamine B Sodium Salt is a rhodamine dye widely used in nonpermanent tattoos. Studies show that Sulforhodamine B can be used as a potential new therapeutic agent for the treatment of the acute respiratory distress syndrome. Group: Biochemicals. Alternative Names: C.I. 45100; Kiton Red S; 3,6-Bis(diethylamino)-9-(2,4-disulfophenyl)-xanthylium Sodium Salt; [6- (Diethylamino) -9- (2, 4-disulfophenyl) -3H-xanthen-3-ylidene] diethylammonium Hydroxide; C.I. Acid Red 52; AR 52; Acid Leather Red KB; Acid Red 52; Acid Red B-SF; Acid Red XB; Acid Rhodamine; Acid Rhodamine B; Acid Rose B; Acid Rose Red B; Aizen Food Red No. 106; Amacid Rhodamine B; Amido Rhodamine B; Best Acid Rhodamine FB; Brilliant Acid Rhodamine B; Brilliant Superlan Rhodamine 2B; Brilliant Superlan Rhodamine B; Colocid Rhodamine B; Colocid Rhodamine BH; Colocid Rhodamine BN; Conacid Red EB; Covasol Red W 4002; Daiwa IJ Red 207H; Daiwa Red 106WB; Dinacid Rhodamine B; Duasyn Acid Rhodamine B 01; Duramine Rhodamine B; Dyacid Red 4B; Dycosacid Rhodamine B; Erio Acid Red XB; Fenazo Pink XXB; Food Color Red No. 1. Grades: Highly Purified. CAS No. 3520-42-1. Pack Sizes: 5g, 25g. Molecular Formula: C27H30N2NaO7S2, Molecular Weight: 580.66. US Biological Life Sciences. | Worldwide |
| Verubecestat TFA | Verubecestat, also known as MK-8931 or SCH 900931, is a potent and selective beta-secretase inhibitor, and BACE1 protein inhibitor or Beta-site APP-cleaving enzyme 1 inhibitor. Verubecestat is a promising novel therapeutic drug candidate in Alzheimer's disease. Verubecestat reduced Aβ cerebral spinal fluids (CSF) levels up to 92% and was well tolerated by patients. Group: Inhibitors. Alternative Names: MK-8931; MK 8931; MK8931; MK-8931-009; SCH 900931; SCH-900931; SCH900931; Verubecestat TFA. CAS No. 2095432-65-6. Molecular formula: C19H18F5N5O5S. Mole weight: 523.44. Appearance: White to off-white solid powder. Purity: >98%. IUPACName: (R)-N-(3-(3-amino-2,5-dimethyl-1,1-dioxido-5,6-dihydro-2H-1,2,4-thiadiazin-5-yl)-4-fluorophenyl)-5-fluoropicolinamide trifluoroacetic acid. Canonical SMILES: O=C (NC1=CC=C (F)C ([C@@] (C2) (C)N=C (N)N (C)S2 (=O)=O)=C1)C3=NC=C (F)C=C3. O=C (O)C (F) (F)F. Catalog: ACM2095432656. | |
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