Acid Synthase Suppliers USA
Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
Product | Description | |
---|---|---|
12(S)-HHTrE Quick inquiry Where to buy Suppliers range | 12(S)-HHTrE is a product of the cyclooxygenase (COX) pathway and one of the primary arachidonic acid metabolites of human platelets. It is biosynthesized by thromboxane (TXA2) synthase from prostaglandin H2 (PGH2) concurrently with TXA2. Synonyms: 12(S)-HHT; 12-hydroxyheptadecatrienoic acid. Grades: ≥95%. CAS No. 54397-84-1. Molecular formula: C17H28O3. Mole weight: 280.4. | |
1,3-Dipalmitoyl-rac-glycerol Quick inquiry Where to buy Suppliers range | 1,3-Dipalmitoyl-rac-glycerol is a diacylglycerol that contains palmitic acid at the sn-1 and sn-3 positions. It activates protein kinase C α (PKCα) in vitro (Ka = 3.8 μM). 1,3-Dipalmitoyl-rac-glycerol (0.25-2 μM) inhibits apoptosis and production of reactive oxygen species (ROS) and pro-inflammatory mediators induced by oxygen-glucose deprivation and reperfusion (OGD/R) in SH-SY5Y neuroblastoma cells. An acyl acceptor for the unspecific bifunctional wax ester synthase/acyl-CoA:Diacylglycerol acyltransferase. Synonyms: 1,3-Dipalmitin; Dipalmitin; 1,3-Dipalmitoyl-glycerol; Glyceryl 1,3-dipalmitate. Grades: ≥98%. CAS No. 502-52-3. Molecular formula: C35H68O5. Mole weight: 568.91. | |
1-(4-sec-Butylphenyl)ethanone Quick inquiry Where to buy Suppliers range | 1-(4-sec-Butylphenyl)ethanone is a useful synthetic intermediate in the synthesis of 2-(p-sec-Butylphenyl)propionic Acid (B692720); an impurity of Ibuprofen (I140000) which is a selective cyclooxygenase inhibitor (IC50=14.9uM) that inhibits PGH synthase-1 and PGH synthase-2 with comparable potency. Group: Biochemicals. Grades: Highly Purified. CAS No. 7645-81-0. Pack Sizes: 1g, 10g. Molecular Formula: C12H16O, Molecular Weight: 176.25. US Biological Life Sciences. | Worldwide |
2,3-Dihydrothieno[3,4-b][1,4]dioxine-2-carboxylic acid Quick inquiry Where to buy Suppliers range | 2,3-Dihydrothieno[3,4-b][1,4]dioxine-2-carboxylic acid, a promising antifungal agent, possesses potent activity against Candidiasis and Aspergillosis. The compound targets 3-ketoacyl-ACP synthase III (FabH), a key enzyme in the biosynthesis of fungal fatty acids, and reduces fungal growth by inducing cellular membrane disruption through inhibition of FabH activity. With its unique mode of action, 2,3-Dihydrothieno[3,4-b][1,4]dioxine-2-carboxylic acid stands as a notably effective potential antifungal therapeutic candidate. Synonyms: 2H,3H-Thieno[3,4-B][1,4]dioxine-2-carboxylic acid; EDOT carboxylic acid; Carboxyedot. CAS No. 955373-67-8. Molecular formula: C7H6O4S. Mole weight: 186.181. | |
2,4-Dihydroxy-6-tridecylbenzoic Acid Quick inquiry Where to buy Suppliers range | 2,4-Dihydroxy-6-tridecylbenzoic Acid is used in pentaketide resorcyclic acid synthesis by type III polyketide synthase from Neurospora crassa. Group: Biochemicals. Grades: Highly Purified. CAS No. 62071-09-4. Pack Sizes: 10mg, 50mg. Molecular Formula: C20H32O4, Molecular Weight: 336.47. US Biological Life Sciences. | Worldwide |
2,4'-Di-O-methylnorsekikaic acid Quick inquiry Where to buy Suppliers range | It is an inhibitor of Prostaglandin synthase. Synonyms: Benzoic acid, 2-hydroxy-3-[(4-hydroxy-2-methoxy-6-propylbenzoyl)oxy]-4-methoxy-6-propyl-; 2,4-Di-O-methylnorsekikasaeure. Grades: ≥98%. CAS No. 69563-43-5. Molecular formula: C22H26O8. Mole weight: 418.44. | |
2,6-Dichlorophenylacetic Acid Quick inquiry Where to buy Suppliers range | 2,6-Dichlorophenylacetic Acid is an impurity of Guanfacine, which is an α2A receptor selective agonist used to treat attention deficit hyperactivity disorder (ADHD) and hypertension. Uses: 2,6-dichlorophenylacetic acid is an inhibitor of isopenicillin n synthase (ipns) and acyl-coa: 6-apa acyltransferase. 2,6-dichlorophenylacetic acid is also part of a group of phenylacetate derivatives that have cytostatic activity against tumour cells. Synonyms: 2,6-Dichlorobenzeneacetic Acid; Guanfacine Impurity 1; Benzeneacetic acid, 2,6-dichloro-. Grades: ≥95%. CAS No. 6575-24-2. Molecular formula: C8H6Cl2O2. Mole weight: 205.04. | |
2-Amino-4-(1-naphthyl)thiazole Quick inquiry Where to buy Suppliers range | 2-Amino-4-(1-naphthyl)thiazole is a reagent used in the synthesis of 2-substituted ethenesulfonic acid ester derivatives as PTP1B inhibitors. Also used as a reagent in the preparation of pirinixic acid derivatives as dual 5-lipoxygenase and microsomal prostaglandin E2 synthase-1 inhibitors for the treatment of inflammation and various cancers. Group: Biochemicals. Grades: Highly Purified. CAS No. 56503-96-9. Pack Sizes: 100mg, 250mg. Molecular Formula: C13H10N2S, Molecular Weight: 226.3. US Biological Life Sciences. | Worldwide |
2-Amino-5,6,7,8-tetrahydro-6-methyl-4(1H)-pteridinone Dihydrochloride Quick inquiry Where to buy Suppliers range | 2-Amino-5,6,7,8-tetrahydro-6-methyl-4(1H)-pteridinone is an analog of tetrahydrobiopterin with cofactor activity for aromatic amino acid hydroxylases. It is also used to study mechanisms of nitric oxide (NO) synthase and free radical induced L-DOPA release from striatal tissue. Group: Biochemicals. Grades: Highly Purified. CAS No. 69113-63-9. Pack Sizes: 100mg, 1g. Molecular Formula: C7H13Cl2N5O, Molecular Weight: 254.12. US Biological Life Sciences. | Worldwide |
2-Chloro-3-fluorobenzoic Acid Quick inquiry Where to buy Suppliers range | 2-Chloro-3-fluorobenzoic Acid is a useful synthetic intermediate. It can be used to synthesize aminobenzhydrol derivatives containing pendant cyclic amines as inhibitors of squalene synthase and cholesterol synthase. It can also be used to prepare aryl aminopyrazole benzamides as oral non-steroidal selective glucocorticoid receptor agonists. Group: Biochemicals. Grades: Highly Purified. CAS No. 102940-86-3. Pack Sizes: 2.5g, 5g. Molecular Formula: C7H4ClFO2, Molecular Weight: 174.56. US Biological Life Sciences. | Worldwide |
2-Chloroisonicotinic Acid Quick inquiry Where to buy Suppliers range | 2-Chloroisonicotinic Acid is a derivative of Isonicotinic Acid (I821760) and is used as a reagent in the synthesis of (phenylmorpholinyl) pyrimidinones as selective and orally active glycogen synthase kinase-3 β inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 6313-54-8. Pack Sizes: 1g, 5 g. Molecular Formula: C6H4ClNO2, Molecular Weight: 157.55. US Biological Life Sciences. | Worldwide |
2-Methylcitric Acid Quick inquiry Where to buy Suppliers range | 2-Methylcitric Acid is a metabolite of Citric Acid. It is formed from the condensation of propionoyl-CoA and oxaloacetic acid catalyzed by a citrate synthase enzyme. 2-Methylcitric acid is an endogenous tricarboxylic acid formed by the condensation of propionyl-CoA with oxaloacetic acid by citrate synthase under conditions of propionyl-CoA accumulation. Accumulation of 2-methylcitric acid is associated with cobalamin deficiencies, propionic acidemia, and methylmalonic acidurias. Group: Biochemicals. Alternative Names: 2-Hydroxy-1,2,3-butanetricarboxylic Acid. Grades: Highly Purified. CAS No. 6061-96-7. Pack Sizes: 50mg, 250mg. Molecular Formula: C?H??O?, Molecular Weight: 206.15. US Biological Life Sciences. | Worldwide |
2-Methylcitric Acid-d3 Quick inquiry Where to buy Suppliers range | 2-Methylcitric Acid-d3 is the isotope labelled analog of 2-Methylcitric Acid (M265080); a metabolite of Citric Acid (C521000) that can be formed from the condensation of propionoyl-CoA and oxaloacetic acid catalyzed by a citrate synthase enzyme. Group: Biochemicals. Grades: Highly Purified. CAS No. 146764-58-1. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C7H7D3O7, Molecular Weight: 209.17. US Biological Life Sciences. | Worldwide |
2-O-Methylsekikaic acid Quick inquiry Where to buy Suppliers range | It is an inhibitor of Prostaglandin synthase with anti-oxidant activity and anti-radical power. Synonyms: Benzoic acid, 3-[(2,4-dimethoxy-6-propylbenzoyl)oxy]-2-hydroxy-4-methoxy-6-propyl-. Grades: ≥98%. CAS No. 69563-42-4. Molecular formula: C23H28O8. Mole weight: 432.46. | |
2-(p-sec-Butylphenyl)propionic Acid Quick inquiry Where to buy Suppliers range | 2-(p-sec-Butylphenyl)propionic Acid (Ibuprofen EP Impurity O) is an impurity of Ibuprofen (I140000); a selective cyclooxygenase inhibitor (IC50=14.9uM) that inhibits PGH synthase-1 and PGH synthase-2 with comparable potency. Group: Biochemicals. Grades: Highly Purified. CAS No. 64451-76-9. Pack Sizes: 250mg, 2.5g. Molecular Formula: C13H18O2, Molecular Weight: 206.28. US Biological Life Sciences. | Worldwide |
2-(p-sec-Butylphenyl)propionic Acid-d3 Quick inquiry Where to buy Suppliers range | 2-(p-sec-Butylphenyl)propionic Acid-d3 is the isotope labelled analog of 2-(p-sec-Butylphenyl)propionic Acid (B692720); an impurity of Ibuprofen (I140000) which is a selective cyclooxygenase inhibitor (IC50=14.9uM) that inhibits PGH synthase-1 and PGH synthase-2 with comparable potency. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 50mg. Molecular Formula: C13H15D3O2, Molecular Weight: 209.3. US Biological Life Sciences. | Worldwide |
(2S, 4R) -4-Azido-1, 2-pyrrolidinedicarboxyl ic Acid 1-(1,1-Dimethylethyl) 2-Methyl Ester Quick inquiry Where to buy Suppliers range | Used in the preparation of neuronal nitric oxide synthase inhibitors. Group: Biochemicals. Alternative Names: (2S, 4R) -4-Azido-1- (tert-butoxycarbonyl) pyrrolidine-2-carboxylic Acid Methyl Ester; (2S-trans) -4-Azido-1, 2-pyrrolidinedicarboxyl ic Acid 1-(1,1-Dimethylethyl) 2-Methyl Ester. Grades: Highly Purified. CAS No. 121147-97-5. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
3-(2-Thienyl)acrylic Acid Quick inquiry Where to buy Suppliers range | 3-(2-Thienyl)acrylic Acid is used as a phenylalanine derivative which shows improved intestinal absorption of insulin in mice. In addition it has been used in the synthesis of novel benzothiazepinones as glycogen synthase kinase-3 β inhibitors. Group: Biochemicals. Alternative Names: 3-(2-Thienyl)-2-propenoic Acid; 2-Thiopheneacrylic Acid; 2-Thienylacrylic Acid; 3-(2-Thienyl)propenoic Acid; 3-(Thien-2-yl)acrylic Acid; 3-(Thiophene-2-yl)acrylic Acid; 3-Thiophen-2-ylacrylic Acid; NSC 4247. Grades: Highly Purified. CAS No. 1124-65-8. Pack Sizes: 10g. US Biological Life Sciences. | Worldwide |
3-Deoxy-2-keto-6-phospho-D-galactonate lithium salt Quick inquiry Where to buy Suppliers range | 3-Deoxy-2-keto-6-phospho-D-galactonate lithium salt, a synthetic chemical compound, represents an innovative derivation in the realm of antibiotic development, demonstrating strong inhibitory effects on the bacterial metabolic pathway involving 3-deoxy-6-phosphogalactonate synthase. A key step towards the next generation of antibiotic regimes, research into this compound has yielded promising results in combating pathogenic microorganisms. Synonyms: 6-phospho-2-dehydro-3-deoxy-D-galactonic acid; 32120-43-7; 6-O-phosphono-3-deoxy-D-threo-hex-2-ulosonic acid; 2-Dehydro-3-deoxy-D-galactonate 6-phosphate; 2-dehydro-3-deoxy-6-phospho-D-galactonate; CHEBI:17860; (4R,5R)-4,5-dihydroxy-2-oxo-6-phosphonooxyhexanoic acid; DTXSID201344249; PD194807; C01286; 3-deoxy-6-O-phosphono-D-threo-hex-2-ulosonic acid; Q27102664. Grades: 95%. CAS No. 32120-43-7. Molecular formula: C6H11O9P·xLi. Mole weight: 258.12 (free acid). | |
4-[2-(2-Amino-4,5,6,7-tetrahydro-4,6-dioxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic Acid Methyl Ester Quick inquiry Where to buy Suppliers range | 4-[2-(2-Amino-4,5,6,7-tetrahydro-4,6-dioxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic acid methyl ester is one of pemetrexed metabolites. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: Benzoic acid, 4-[2-(2-amino-4,5,6,7-tetrahydro-4,6-dioxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]-, methyl ester; Pemetrexed Impurity 63; Methyl 4-[2-(2-amino-4,6-dioxo-4,5,6,7-tetrahydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoate; Methyl 4-(2-(2-imino-4,6-dioxo-2,3,4,5,6,7-hexahydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoate. Grades: ≥95%. CAS No. 1320346-43-7. Molecular formula: C16H16N4O4. Mole weight: 328.32. | |
4'-O-Methylpaludosic acid Quick inquiry Where to buy Suppliers range | It is an inhibitor of Prostaglandin synthase. Synonyms: Benzoic acid, 2-hydroxy-3-[(4-hydroxy-2-methoxy-6-propylbenzoyl)oxy]-4-methoxy-6-pentyl-. Grades: ≥98%. CAS No. 69563-44-6. Molecular formula: C24H30O8. Mole weight: 446.49. | |
5-Bromo-dUMP Quick inquiry Where to buy Suppliers range | 5-Bromo-dUMP is a highly active inhibitor of thymidylate synthase, serving as a pivotal component in hindering the catalytic ability of this vital enzyme involved in the research and development of DNA. Its efficacious employment as an antitumor compound against diverse malignancies proficiently impedes the generation of DNA, thus efficaciously curbing the proliferation of malignant cells inherent to cancerous growths. Synonyms: (5Br-dUMP); 5-Bromo-2'-deoxyuridine-5'-monophosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 6666-38-2. Molecular formula: C9H12N2O8PBr (free acid). Mole weight: 387.08 (free acid). | |
5-Fluoro-UTP Quick inquiry Where to buy Suppliers range | 5-Fluoro-UTP is an DNA/RNA synthesis inhibitor that terminate synthesis of nucleotide through inhibiting thymidylate synthase. It is used as an anticancer drug. Uses: 5-fluoro-utp is an dna/rna synthesis inhibitor. Synonyms: (5F-UTP); 5-Fluoro-uridine-5'-triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 3828-96-4. Molecular formula: C9H14N2O15P3F (free acid). Mole weight: 502.13 (free acid). | |
(6R)-5,6,7,8-Tetrahydro-L-biopterin 2HCl Quick inquiry Where to buy Suppliers range | Tetrahydrobiopterin is a naturally occurring essential cofactor of the three aromatic amino acid hydroxylase enzymes, used in the degradation of amino acid phenylalanine and in the biosynthesis of the neurotransmitters serotonin, melatonin, dopamine, norepinephrine , epinephrine, and is a cofactor for the production of nitric oxide by the nitric oxide synthases. Chemically, its structure is that of a reduced pteridine derivative. Group: Biochemicals. Alternative Names: (6R)-5,6,7,8-Tetrahydrobiopterin dihydrochloride; 6R-BH4; Sapropterin; Sapropterin dihydrochloride; BioMarin T 1401, Biopten, Kuvan, SUN 0588; Shiratori SN 0588. Grades: Highly Purified. CAS No. 69056-38-8,17528-72-2. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C?H??N?O?; 2(HCl), Molecular Weight: 314.17. US Biological Life Sciences. | Worldwide |
8,11-Eicosadiynoic acid Quick inquiry Where to buy Suppliers range | 8,11-Eicosadiynoic acid is an acetylenic fatty acid which inhibits arachidonic acid metabolism at several unrelated stages. 8,11-Eicosadiynoic acid inhibits the enzymes, arachidonoyl synthase, acyl-CoA synthase, Δ-5-desaturase, COX, and also arachidonic acid uptake by platelets. Synonyms: EDYA; Eicosa-8,11-diynoic acid. Grades: ≥95%. CAS No. 82073-91-4. Molecular formula: C20H32O2. Mole weight: 304.5. | |
9-Bromononanoic acid Quick inquiry Where to buy Suppliers range | 9-Bromononanoic acid, an instrumental biochemical reagent, finds ubiquitous use in several industrial processes including the synthesis of pharmaceutical drugs. Known for its inhibitory properties against fatty acid synthase, its prowess extends to manufacturing surfactants, detergents while also being extensively used as a building block in organic synthesis. This acid's multifunctional attributes coupled with its incomparable industrial benefits are a testament to its quintessential role in modern chemistry. Synonyms: Nonanoic acid, 9-bromo-; 9-bromo-nonanoic acid; 9-bromo-n-nonanoic acid. CAS No. 41059-02-3. Molecular formula: C9H17BrO2. Mole weight: 237.13. | |
Acetoacetamide Quick inquiry Where to buy Suppliers range | A building block that has been used in the preparation of glycogen synthase kinase 3 (GSK-3) inhibitors. Synonyms: 3-Oxobutanamide; 3-Oxobutyramide; Acetoacetic acid amide. Grades: > 95%. CAS No. 5977-14-0. Molecular formula: C4H7NO2. Mole weight: 101.11. | |
Acetoxyacetic acid Quick inquiry Where to buy Suppliers range | Acetoxyacetic acid (CAS# 13831-30-6) is a versatile organic building block, used in the synthesis of pharmaceutical compounds, including inhibitors and therapeutic agents. It can be used for the synthesis of analogs of 5-Aminolevulinic Acid, which are potential inhibitors of ALA dehydratase (porphobilinogen synthase), an early enzyme of tetrapyrrole biosynthesis. Synonyms: 2-acetyloxyacetic acid. CAS No. 13831-30-6. Molecular formula: C4H6O4. Mole weight: 118.09. | |
Acivicin Quick inquiry Where to buy Suppliers range | Acivicin is an isoxazole antibiotic isolated from Streptomyces. sviceus. Acivicin is a glutamine analog that irreversibly inhibits glutamine-dependent amidotransferases involved in nucleotide and amino acid biosynthesis (Kis = 10 and 560 μM for anthranilate synthase and glutamate synthase, respectively) as a potent antitumor antibiotic that induces apoptosis in human lymphoblastoid cells. Acivicin is an inhibitor of GGT used for solid tumor research. Uses: Protease inhibitor. Synonyms: (S-(R*,R*))-4,5-Dihydro-alpha-amino-3-chloro-5-isoxazoleacetic acid; (alpha-S,5S)-alpha-Amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid; (alphaS,5S)-alpha-Amino-3-chlor-4,5-dihydro-5-isoxazolylessigsaeure. Grades: ≥98% by HPLC. CAS No. 42228-92-2. Molecular formula: C5H7ClN2O3. Mole weight: 178.57. | |
Adamantoic Acid Quick inquiry Where to buy Suppliers range | Adamantoic Acid is an inhibitor of chorismate mutase activity and hydroxyphenylpyruvate synthase. It inhibits TTR conformational changes facilitating amyloid fibril formation. Group: Biochemicals. Alternative Names: 1-Adamantanecarboxylic Acid; 1-Adamantane-1-carboxylic Acid; 1-Adamantylcarboxylic Acid; 1-Carboxyadamantane; NSC 94182; Tricyclo[3.3.1.13, 7]decane-1-carboxylic Acid. Grades: Highly Purified. CAS No. 828-51-3. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
Agmatine sulfate salt Quick inquiry Where to buy Suppliers range | Agmatine sulfate, the sulfate preparation of Agmatine, is an endogenous agonist at imidazoline receptor and a NO synthase inhibitor. Agmatine displaces clonidine at α2-adrenergic and at imidazoline receptors and produces blockade of the NMDA-receptor associated cation channels. Nutritional supplement in health care products. Uses: Ingredient of health care products. Synonyms: 2-(4-aminobutyl)guanidine;sulfuric acid. Grades: ≥ 93 % (HPLC). CAS No. 2482-00-0. Molecular formula: C5H16N4O4S. Mole weight: 228.27. | |
Alendronate sodium (MK 217) Quick inquiry Where to buy Suppliers range | Osteoclast-mediated bone resorption inhibitor. Binds and blocks farnesyl diphosphate synthase (FPPS) in the HMG-CoA pathway (IC50 = 460nM for recombinant human FPPS); causes macrophage apoptosis. Inhibits prenylation and sterol biosynthesis in purified osteoclasts. Group: Biochemicals. Alternative Names: P,P'-(4-Amino-1-hydroxybutylidene)bis-phosphonic acid monosodium salt. Grades: Purified. CAS No. 129318-43-0. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
Alendronate sodium (Sodium [4-amino-1-hydroxy-1-(hydroxy-oxido-phosphoryl)- butyl]phosphonic acid, trihydrate, MK-217, Fosamax) Quick inquiry Where to buy Suppliers range | Alendronate sodium is a bisphosphonate that acts as a specific inhibitor of osteoclast-mediated bone resorption. It inhibits bone resorption in vitro with an IC?? value of 2nm. Also acts as a farnesyl diphosphate synthase inhibitor (IC?? =460nm) and CD45 protein tyrosine phosphatase inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 121268-17-5. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
Aminoethoxyvinyl glycine Hydrochloride (ABG 3168) Quick inquiry Where to buy Suppliers range | Ethylene, an important plant regulator, is synthesized from S-adenosyl-L-methionine by the sequential action of 1-amino-cyclopropane-carboxylate (ACC) synthases (ACSs) and ACC oxidases (ACOs). Aminoethoxyvinyl glycine is an inhibitor of ethylene biosynthesis that, at 1uM, blocks the activity of both ACSs and ACOs.1 Through this action, it reduces ethylene-mediated changes in plant growth and development.2,3,4 Aminoethoxyvinyl glycine also inhibits cystathionine γ-lyase (Ki = 10.5uM) with slow- and tight-binding characteristics.5. Group: Biochemicals. Alternative Names: (2S,3E)-2-Amino-4-(2-aminoethoxy)-3-butenoic Acid Monohydrochloride; [S-(E)]-2-Amino-4-(2-aminoethoxy)-3-butenoic Acid Monohydrochloride; (S)-trans-2-Amino-4-(2-aminoethoxy)-3-butenoic Acid Hydrochloride; ABG 3168 Hydrochloride; L-2-Amino-4-(2'-aminoethoxy)-trans-3-butenoic Acid Hydrochloride; ReTain Hydrochloride; ReTain (plant growth regulator) Hydrochloride. Grades: Highly Purified. CAS No. 55720-26-8. Pack Sizes: 1mg, 5mg, 10mg. Molecular Formula: C?H??ClN?O?, Molecular Weight: 196.63. US Biological Life Sciences. | Worldwide |
Antibiotic 1233B Quick inquiry Where to buy Suppliers range | It is a β-lactone antibiotic produced by the strain of Cephalosporium sp. It has a strong inhibitory effect on hydroxymethyl glutaryl coenzyme A (HMG-CoA) synthase. Synonyms: 1233B; 3,5,7-trimethyl-12-hydroxy-13-hydroxymethyl-2,4-tetradecadiendioic acid; 2,4-Tetradecadienedioic acid, 12-hydroxy-13-(hydroxymethyl)-3,5,7-trimethyl-. CAS No. 34668-58-1. Molecular formula: C18H30O6. Mole weight: 342.43. | |
ANX-510 Quick inquiry Where to buy Suppliers range | ANX-510 is a folate-based biomodulator with potential antineoplastic activity. 5,10-methylenetetrahydrofolate (MTHF) stabilizes the covalent binding of the fluorouracil metabolite 5-5-fluoro-2'-deoxyuridine-5'-O-monophosphate (FdUMP) to its target enzyme, thymidylate synthase, which results in inhibition of thymidylate synthase, depletion of thymidine triphosphate (TTP), a necessary constituent of DNA, and tumor cell death. Synonyms: 5,10-Methylenetetrahydrofolic acid; 5,10-Methylene-tetrahydrofolate; Tetrahydromethylenefolate; N-{4-[3-amino-1-oxo-1,2,5,6,6a,7-hexahydroimidazo[1,5-f]pteridin-8(9H)-yl]benzoyl}-L-glutamic acid. CAS No. 3432-99-3. Molecular formula: C20H23N7O6. Mole weight: 457.44. | |
BGC-638 Quick inquiry Where to buy Suppliers range | BGC-638, an analogue of BGC-945, is a thymidylate synthase inhibitor specifically transported into α-folate receptor (α-FR)-overexpressing tumors. Synonyms: BGC 638; BGC638; CB300638; CB-300638; D-Glutamic acid, N-(4-(2-propyn-1-yl((6S)-4,6,7,8-tetrahydro-2-methyl-4-oxo-3H-cyclopenta(g)quinazolin-6-yl)amino)benzoyl)-L-gamma-glutamyl-. CAS No. 416852-27-2. Molecular formula: C32H33N5O9. Mole weight: 631.64. | |
BGC-945 Quick inquiry Where to buy Suppliers range | BGC 945 is a cyclopenta[g]quinazoline-based, thymidylate synthase inhibitor specifically transported into α-folate receptor (α-FR)-overexpressing tumors. BGC 945 has low affinity for the widely expressed reduced-folate carrier (RFC). BGC 945 selectively inhibits thymidylate synthase in α-FR-overexpressing tumors and should cause minimal toxicity to humans at therapeutic doses. Synonyms: Idetrexed; ONX-0801; N-[4-[2-Propynyl[(6S)-4,6,7,8-tetrahydro-2-(hydroxymethyl)-4-oxo-1H-cyclopenta[g]quinazolin-6-yl]amino]benzoyl]-L-γ-glutamyl-D-glutamic acid; N-[4-[2-Propyn-1-yl[(6S)-4,6,7,8-tetrahydro-2-(hydroxymethyl)-4-oxo-3H-cyclopenta[g]quinazolin-6-yl]amino]benzoyl]-L-γ-glutamyl-D-glutamic acid; (R) -2- ( (S) -4-carboxy-4- (4- ( ( (S) -2- (hydroxymethyl) -4-oxo-4, 6, 7, 8-tetrahydro-3H-cyclopenta[g]quinazolin-6-yl) (prop-2-yn-1-yl) amino) benzamido) butanamido) pentanedioic acid. Grades: ≥95%. CAS No. 501332-69-0. Molecular formula: C32H33N5O10. Mole weight: 647.63. | |
BMS-188494 Quick inquiry Where to buy Suppliers range | BMS-188494 is the prodrug of BMS-187745, a squalene synthase inhibitor used as an anticholesterol drug. Synonyms: 1-[bis (2, 2-dimethylpropanoyloxymethoxy) phosphoryl]-4- (3-phenoxyphenyl) butane-1-sulfonic acid; BMS-188494; BMS 188494; BMS188494; UNII-F4W2579G7P. Grades: >98%. CAS No. 191866-32-7. Molecular formula: C28H39O11PS. Mole weight: 614.645. | |
C75 Quick inquiry Where to buy Suppliers range | C75 is a novel, potent synthetic inhibitor of fatty acid synthase (FAS), which is used as a tool for studying fatty acid synthesis in metabolic disorders and cancer. Synonyms: C 75 trC-75 trans-racemic; trans-C75; C 75; C75; C-75. Grades: >98%. CAS No. 218137-86-1. Molecular formula: C14H22O4. Mole weight: 254.32. | |
C75 trans Quick inquiry Where to buy Suppliers range | trans-Tetrahydro-4-methylene-2-octyl-5-oxo-3-furancarboxylic Acid is a well-known fatty acid synthase (FAS) inhibitor. Studies show that trans-Tetrahydro-4-methylene-2-octyl-5-oxo-3-furancarboxylic Acid is a cell cycle arrest inducer in hepatocellular carcinoma (HCC) cell lines. It has also been shown to blocks resistin-induced increases in lipid accumulation by human macrophages. Synonyms: C 75 trC-75 trans-racemic; trans-C75. Grades: >98%. CAS No. 191282-48-1. Molecular formula: C14H22O4. Mole weight: 254.32. | |
c[8-AET-G(2',5')pA(3',5')p] Quick inquiry Where to buy Suppliers range | c[8-AET-G(2',5')pA(3',5')p] is an analogue of c[G(2',5')pA(3',5')p], the metazoan cyclic dinucleotide second messenger and STING activator, which is used as a ligand for affinity chromatography or for coupling of labelling structures such as fluorophores. c[G(2',5')pA(3',5')p] is the metazoan second messenger produced by cGAMP synthase (cGAS), the mammalian intrinsic immune DNA sensor. Synonyms: Cyclic (8- (2- aminoethylthio)guanosine- (2' -≥ 5')- monophosphate- adenosine- (3' -≥ 5')- monophosphate), sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C22H29N11O13P2S (free acid). Mole weight: 749.6 (free acid). | |
c[8-Br-G(2',5')pA(3',5')p] Quick inquiry Where to buy Suppliers range | c[8-Br-G(2',5')pA(3',5')p] is an analogue of c[G(2',5')pA(3',5')p], the metazoan cyclic dinucleotide second messenger, which can be used for binding studies and as precursor for further modifications with spacers or labels. c[G(2',5')pA(3',5')p] is the metazoan second messenger produced by cGAMP synthase (cGAS), the mammalian intrinsic immune DNA sensor. Synonyms: Cyclic (8- bromoguanosine- (2' -≥ 5')- monophosphate- adenosine- (3' -≥ 5')- monophosphate), sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C20H23BrN10O13P2 (free acid). Mole weight: 753.3 (free acid). | |
CAY10434 Quick inquiry Where to buy Suppliers range | 20-HETE is an important metabolite of arachidonic acid in the vasculature, where it is synthesized by cytochrome P450 (CYP450) enzymes of the 4A family. CAY10434 is a selective inhibitor of the 20-HETE synthase CYP4A11 displaying an IC50 value of 8.8 nM when tested in human renal microsomes. It is nearly 200 times less potent as an inhibitor of 1A, 1C, and 3A CYP450 enzymes. Synonyms: CAY 10434; CAY-10434. Grades: ≥98%. CAS No. 769917-29-5. Molecular formula: C17H25N3O. Mole weight: 287.4. | |
CAY10462 Quick inquiry Where to buy Suppliers range | 20-HETE is an important metabolite of arachidonic acid in the vasculature, especially in the kidney, where it is synthesized by cytochrome P450 (CYP450) enzymes of the 4A family. CAY10462 is the hydrochloride salt form of CAY10434. It is a selective inhibitor of the 20-HETE synthase CYP4A11, which exhibits an IC50 of 8.8 nM when tested in human renal microsomes. Synonyms: CAY 10462; CAY-10462. Grades: ≥98%. CAS No. 502656-68-0. Molecular formula: C17H25N3O·2HCl. Mole weight: 360.3. | |
CB30900 Quick inquiry Where to buy Suppliers range | CB30900 has been found to be a thymidylate synthase inhibitor that could have some extent of activity in models with low or defective folylpolyglutamate synthetase. Synonyms: CB 30900; CB30900; CB-30900; N-(N-(4-(N-((3,4-Dihydro-2,7-dimethyl-4-oxo-6-quinazolinyl)methyl)-N-prop-2-ynylamino)-2-fluorobenzoyl)-L-gamma-glutamyl)-D-glutamic acid. Grades: 98%. CAS No. 145788-82-5. Molecular formula: C31H32FN5O9. Mole weight: 637.61. | |
CB 3731 Quick inquiry Where to buy Suppliers range | CB 3731 can be used in fluorine-19 nuclear magnetic resonance studies of binary and ternary complexes of thymidylate synthase. Synonyms: CB 3731; CB-3731; CB3731. N-(4-((N-(2-Amino-4-hydroxy-6-quinazolinyl)methyl)-N-(fluoroethyl)amino)benzoyl)glutamic acid. Grades: 98%. CAS No. 80015-07-2. Molecular formula: C23H24FN5O6. Mole weight: 458.47. | |
CDDO Imidazolide Quick inquiry Where to buy Suppliers range | CDDO Imidozolide (CDDO-Im) is a synthetic triterpenoid CDDO-Im inhibits fatty acid synthase expression and has antiproliferative and proapoptotic effects in human liposarcoma cells. Studies show that CDDO-Im is highly active in suppressing cellular proliferation of human leukemia and breast cancer cell lines as well as being an effective therapeutic agent in the treatment of other types of cancers. Group: Biochemicals. Alternative Names: 1-(2-Cyano-3,12,28-trioxooleana-1,9(11)-dien-28-yl)-1H-imidazole; 2-Cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid imidazolide; CDDO-Im; RTA 403; TP 235. Grades: Highly Purified. CAS No. 443104-02-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Cerulenin (2,3-Epoxy-4-oxo-7,10-dodecadienamide) Quick inquiry Where to buy Suppliers range | Antibiotic. Fatty acid synthase (FAS) inhibitor, reported to bind in equimolar ratio to B-keto-acyl- ACP synthase, thus inhibiting protein acylation. Produces metabolic effects similar to effects of leptin, but through mechanisms that are independent of, or down-stream from, both leptin and melanocortin receptors. Apoptosis inducer. Inhibitor of bacterial fatty acid synthesis (inhibits FabH, FabB and FabF condensation enzymes). Group: Biochemicals. Grades: Highly Purified. CAS No. 17397-89-6. Pack Sizes: 5mg. Molecular Formula:C12H17NO3 MOLECULAR WEIGHT: 223.3. US Biological Life Sciences. | Worldwide |
Cerulenin (Helicocerin, NSC 116069, 2,3-Epoxy-4-oxo-7,10-dodecadienamide) Quick inquiry Where to buy Suppliers range | Cerulenin is an epoxy fatty acid amide isolated from the fungus Cephalosporium caerulens and identified as an antifungal in the 1960s. Over the past 40 years cerulenin has found broad application in lipid biochemistry as an inhibitor fatty acid and sterol biosynthesis. Cerulenin binds to B-keto-acyl-ACP synthase blocking the interaction of malonyl CoA. Cerulenin is also an inhibitor of bacterial fatty acid synthesis acting on the FabH, FabB and FabF condensation enzymes. Cerulenin stimulates fatty acid oxidation and inhibits HMG-CoA synthetase activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 17397-89-6. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
Chlorimuron Ethyl Quick inquiry Where to buy Suppliers range | Chlorimuron Ethyl. Uses: Chlorimuron ethyl inhibits actetolactate synthase (ALS), an enzyme involved in synthesis of branched chain amino acids including valine, leucine, and isoleucine. Group: Pheromone Ingredients. Grades: 95.0%. CAS No. 90982-32-4. Molecular formula: C15H15ClN4O6S. Mole weight: 414.82. | |
Cindunistat hydrochloride maleate Quick inquiry Where to buy Suppliers range | Cindunistat is a selective Nitric oxide synthase (iNOS) type II inhibitor. It is potentially useful in patients with symptomatic osteoarthritis of the knee. But in Feb 2012, Phase-II/III for Osteoarthritis was discontinued. Uses: Osteoarthritis. Synonyms: PHA-728669F; PHA 728669F; PHA728669F; SD-6010; SD 6010; SD6010 PF-00572986; PF00572986; PF 00572986; PF-572986; PF572986; PF 572986; PHA-84250; PHA84250; PHA 84250; SC-084250; SC 084250; SC084250; Cindunistat. cindunistat hydrochloride maleate;(R,Z)-2-amino-3-((2-((1-aminoethylidene)amino)ethyl)thio)-2-methylpropanoic acid compound with maleic acid (2:1) hydrochloride. Grades: 98%. CAS No. 753491-31-5. Molecular formula: C20H39ClN6O8S2. Mole weight: 591.15. | |
Corallopyronin C Quick inquiry Where to buy Suppliers range | It is produced by the strain of Corallococcus (Myxococcus) coralloides. It is a bacterial RNA synthase inhibitor, mainly resistant to gram-positive bacteria. Synonyms: [(E)-5-(4-Hydroxy-5-{(E)-2-methyl-4-[2-methyl-5-((1Z,4E)-1-methyl-hexa-1,4-dienyl)-tetrahydro-furan-2-yl]-but-3-enoyl}-6-oxo-6H-pyran-2-yl)-hex-1-enyl]-carbamic acid methyl ester; [5-[4-Hydroxy-3-[2-methyl-1-oxo-4-[tetrahydro-2-methyl-5-(1-methyl-1,4-hexadienyl)furan-2-yl]-3-butenyl]-2-oxo-2H-pyran-6-yl]-1-hexenyl]carbamic acid methyl ester. CAS No. 96717-74-7. Molecular formula: C30H41NO7. Mole weight: 527.65. | |
Crosstide TFA Quick inquiry Where to buy Suppliers range | Crosstide, a peptide analog of glycogen synthase kinase α/β fusion protein sequence, acts as a substrate for Akt (PKB) (Km=4μM) and is useful in phosphocellulose kinase assays. Synonyms: H-Gly-Arg-Pro-Arg-Thr-Ser-Ser-Phe-Ala-Glu-Gly-OH.TFA; glycyl-L-arginyl-L-prolyl-L-arginyl-L-threonyl-L-seryl-L-seryl-L-phenylalanyl-L-alanyl-L-alpha-glutamyl-glycine trifluoroacetic acid; Crosstide trifluoroacetate salt. Grades: ≥95%. Molecular formula: C50H78F3N17O19. Mole weight: 1278.25. | |
Cysteine, S-Nitrosylated (SNO-Cys) (BSA) Quick inquiry Where to buy Suppliers range | Nitric oxide (NO), generated by cell type-specific NO- synthase (NOS) isoforms, is a freely diffusible intercellular messenger that functions in target cells in NOS-dependent signaling. S-nitrosylation of cysteine thiols in proteins by the highly labile NO radical has been identified as an important effector of NO-related bioactivity both in NOS- containing cells and intercellular signaling. Most cells contain low levels of nitrosylated proteins that are thought to be regulated by S-nitrosylation and denitrosylation. S-nitrosylation of proteins serves as a ubiquitous post- translational modification that dynamically regulates a broad functional spectrum of proteins. The majority of these proteins are regulated by S-nitrosylation on a single critical cysteine residue within an acidic/basic or hydrophobic structural motif that may also be subject to oxygen- or glutathione-dependent modification. NO- sensitive ion channels including the cardiac and skeletal muscle ryanodine receptor (RyR1 Group: Biochemicals. Grades: Purified. Pack Sizes: 100ug. US Biological Life Sciences. | Worldwide |
Denifanstat Quick inquiry Where to buy Suppliers range | Denifanstat is an orally bioavailable fatty acid synthase (FASN) inhibitor, with potential antineoplastic activity. Synonyms: FASN-IN-2; TVB-2640; 4-(1-(4-Cyclobutyl-2-methyl-5-(5-methyl-4H-1,2,4-triazol-3-yl)benzoyl)piperidin-4-yl)benzonitrile; TVB2640; TVB 2640; FASN inhibitor 2; Benzonitrile, 4-[1-[4-cyclobutyl-2-methyl-5-(3-methyl-1H-1,2,4-triazol-5-yl)benzoyl]-4-piperidinyl]-. Grades: ≥97%. CAS No. 1399177-37-7. Molecular formula: C27H29N5O. Mole weight: 439.55. | |
Dexamethasone Sodium Phosphate Bisulfate Adduct Quick inquiry Where to buy Suppliers range | Dexamethasone Sodium Phosphate Bisulfate Adduct is a product of additions of sodium phosphate and sodium bisulfate to Dexamethasone. Dexamethasone is a glucocorticoid used as an anti-inflammatory agent. Dexamethasone regulates T cell survival, growth, and differentiation. Dexamethasone inhibits the induction of nitric oxide synthase. Group: Biochemicals. Alternative Names: (11beta,16alpha)-9-Fluoro-11,17-dihydroxy-16-methyl-3,20-dioxo-21-(phosphonooxy)-pregn-4-ene-1-sulfonic Acid Disodium Salt,9-Fluoro-11beta,17,21-trihydroxy-16alpha-methyl-3,20-dioxo-pregn-4-ene-1-sulfonic Acid 21-(dihydrogen phosphate) Disodium Salt. Grades: Highly Purified. CAS No. 39005-10-2. Pack Sizes: 5mg. Molecular Formula: C22H30FNa2O11PS. US Biological Life Sciences. | Worldwide |
D-Pemetrexed Dimethyl Diester Quick inquiry Where to buy Suppliers range | D-Pemetrexed dimethyl diester is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid 1,5-Dimethyl Diester. Grades: 98%. CAS No. 1391068-12-4. Molecular formula: C22H25N5O6. Mole weight: 455.46. | |
D-Pemetrexed Hydrate Quick inquiry Where to buy Suppliers range | D-Pemetrexed Hydrate is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-D-glutamic Acid Hydrate. Molecular formula: C20H23N5O7. Mole weight: 445.42. | |
Edatrexate Quick inquiry Where to buy Suppliers range | Edatrexate is a polyglutamatable folate antagonist analogue of methotrexate with antineoplastic activity. Edatrexate inhibits dihydrofolate reductase, thereby increasing cellular levels of polyglutamates, inhibiting thymidylate synthase and glycinamide ribonucleotide formyl transferase, impairing synthesis of purine nucleotides and amino acids, and resulting in tumor cell death. Edatrexate may overcome tumor resistance to methotrexate, which loses its activity after it is polyglutamated. Uses: Antineoplastic agents. Synonyms: 10-ethyl-deaza-aminopterin; 10-EDAM; 10 EDAM; 10EDAM; CGP-30694; CGP30694; CGP30694; D 03942; D-03942; D03942. CAS No. 80576-83-6. Molecular formula: C22H25N7O5. Mole weight: 467.49. | |
Eliglustat hemitartrate Quick inquiry Where to buy Suppliers range | Eliglustat hemitartrate is a specific inhibitor of glucosylceramide synthase. It is under development as an oral substrate reduction therapy for Gaucher disease type 1 (GD1). It was developed by Genzyme Corp and has been listed by the FDA August 2014. Synonyms: Genz-112638; Genz 112638; Genz112638; Eliglustat tartrate; Bis(N-((1R,2R)-2-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-hydroxy-1-(pyrrolidin-1- ylmethyl)ethyl)octanamide) (2R,3R)-2,3-dihydroxybutanedioate; Octanamide, N-((1R,2R)-2-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-hydroxy-1-(1- pyrrolidinylmethyl)ethyl)-, (2R,3R)-2,3-dihydroxybutanedioate; N-[(1R,2R)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-pyrrolidin-1-ylpropan-2-yl]octanamide (2R,3R)-2,3-dihydroxybutanedioic acid. Grades: >98%. CAS No. 928659-70-5. Molecular formula: C50H78N4O14. Mole weight: 959.17. | |
Enfumafungin Quick inquiry Where to buy Suppliers range | Enfumafungin is a triterpene glycoside and hemiacetal isolated from a fermentation of Hormonema sp. Enfumafungin is an antifungal agent that acts on fungal cell walls as an inhibitor of (1,3)-beta-D-glucan synthase. It is specific for yeast and fungi (excluding Cryptococcus) and does not inhibit the growth of Bacillus subtilis. Synonyms: 4H-1,4a-Propano-2H-phenanthro[1,2-c]pyran-7-carboxylic acid, 14-(acetyloxy)-8-[(1R)-1,2-dimethylpropyl]-15-(β-D-glucopyranosyloxy)-1,6,6a,7,8,9,10,10a,10b,11,12,12a-dodecahydro-4-hydroxy-1,6a,8,10a-tetramethyl-, (1S, 4aR, 6aS, 7R, 8R, 10aR, 10bR, 12aS, 14R, 15R)-. Grades: ≥98%. CAS No. 260979-95-1. Molecular formula: C38H60O12. Mole weight: 708.88. | |
Ethyl 3-Methyl-2-butenoate Quick inquiry Where to buy Suppliers range | Ethyl 3-Methyl-2-butenoate is used in the synthesis of Endothelin-A antagonist ABT-546 used in the preparation of antidepressant Rolipram. Also used in the synthesis of potent inhibitors of human inducible nitric oxide synthases, important enzymes in cellular signaling. Group: Biochemicals. Alternative Names: 3-Methyl-2-butenoic Acid Ethyl Ester; 3-Methyl-2-butenoic Acid Ethyl Ester; Ethyl 3,3-Dimethylacrylate; Ethyl 3-Methyl-2-butenoate; Ethyl 3-Methylcrotonate; Ethyl Dimethylacrylate; Ethyl Isobutenoate; Ethyl Isopropylideneacetate; Ethyl Senecioate; Ethyl β, β-Dimethylacrylate; Ethyl β-Methylcrotonate; NSC 61853; NSC 99208. Grades: Highly Purified. CAS No. 638-10-8. Pack Sizes: 10g. US Biological Life Sciences. | Worldwide |
F-10748 C1 Quick inquiry Where to buy Suppliers range | F-10748 C1 is originally isolated from Lophodermium sp. SANK 18496. It had inhibitory activity against fungal 1,3-β-glucan synthase with IC50 of 0.2-2 μg/mL. Synonyms: 2,4,12-Hexadecatrienoic acid, 7-hydroxy-8,14-dimethyl-, 3', 4', 5', 6'-tetrahydro-3', 5, 7-trihydroxy-6'- (hydroxymethyl) -5'- [ [6-O- (1-oxopentyl) hexopyranosyl]oxy]spiro [isobenzofuran-1 (3H) , 2'- [2H]pyran]-4'-y l ester, (2E,4E,12E)-. Molecular formula: C42H62O16. Mole weight: 822.93. | |
FAS-IN-1 Quick inquiry Where to buy Suppliers range | FAS-IN-1, a diazaspiro derivative, has been found to be a fatty acid synthase inhibitor that probably have potential biological usage in anticancer study. Uses: Fas-in-1 has been found to be a fatty acid synthase inhibitor that probably have potential biological usage in anticancer study. Synonyms: FAS-IN-1; FAS IN 1; CHEMBL2147032; SCHEMBL4541971; OGGOWHOQMIINAZ-UHFFFAOYSA-N; BDBM50391837; BDBM 50391837; BDBM-50391837; CS 3932; CS3932; CS-3932. Grades: 98%. CAS No. 1375105-96-6. Molecular formula: C26H27N3O4S. Mole weight: 477.58. | |
FAS Inhibitor, C75 (Trans-4-carboxy-5-octyl-3-methylene-butyrolactone) Quick inquiry Where to buy Suppliers range | Inhibitor of fatty acid synthase (FAS) reducing food intake and body weight in mice. Exhibits irreversible slow-binding biphasic inactivation of FAS. Down regulates neuropeptide Y and Agouti-related protein expression. Has been proposed to activiate CPT-1 activity in liver and adipose tissue, leading to increased fatty acid oxidation and energy production. Shows significant in vivo antitumor activity in human breast cancer cells.Suppresses DNA replication and induces apoptosis. FAS inhibition by C75 leads to dramatic accumulation of the CDK inhibitor p27KIP1 from cytosol to cell nuclei. Group: Biochemicals. Alternative Names: [Trans-4-carboxy-5-octyl-3-methylene-butyrolactone]. Grades: Highly Purified. CAS No. 191282-48-1. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Fasnall benzenesulfonate Quick inquiry Where to buy Suppliers range | Fasnall is an inhibitor of fatty acid synthase (FAS) with an IC50 value of 3.71 μM for the human recombinant enzyme. Synonyms: 5,6-Dimethyl-N-[1-(phenylmethyl)-3-pyrrolidinyl]thieno[2,3-d]pyrimidin-4-amine benzenesulfonate; N-(1-Benzylpyrrolidin-3-yl)-5,6-dimethylthieno[2,3-d] pyrimidin-4-amine benzenesulfonate. Grades: ≥98%. CAS No. 2187367-11-7. Molecular formula: C19H22N4S·C6H6O3S. Mole weight: 496.6. | |
FdUTP Quick inquiry Where to buy Suppliers range | FdUTP, a remarkable nucleoside triphosphate, puts the brakes on thymidylate synthase, striking a fatal blow to DNA precursor synthesis and culminating in cellular collapse. This versatile substance has proven tadpole in tackling a gamut of solid tumors, from the grisly colorectal specter to the dauntingly defiant breast cancer. Synonyms: 5-Fluoro-2'-deoxyuridine-5'-triphosphate. Grades: ≥ 95 % (HPLC). Molecular formula: C9H14N2O14P3F (free acid). Mole weight: 486.1 (free acid). | |
Fumonisin B3 Quick inquiry Where to buy Suppliers range | Fumonisin B3 is a mycotoxin produced by Fusarium moniliforme which is the most commonly reported fungal species infecting maize. Fumonisins acts as an inhibitor of ceramide synthase (sphingosine N-acyltransferase). Synonyms: FB3; (2R,2'R)-2,2'-((((5R,6R,7S,9S,11R,18S,19S)-19-Amino-11,18-dihydroxy-5,9-dimethylicosane-6,7-diyl)bis(oxy))bis(2-oxoethane-2,1-diyl))disuccinic Acid. Grades: ≥98%. CAS No. 1422359-85-0. Molecular formula: C34H59NO14. Mole weight: 705.83. | |
Furegrelate sodium salt Quick inquiry Where to buy Suppliers range | Furegrelate is a selective and potent inhibitor of thromboxane synthase with an IC50 value of 15 nM for human platelet microsomal thromboxane synthase. Synonyms: U-63557A; 5-(3-pyridinylmethyl)-2-benzofurancarboxylic acid, sodium salt. Grades: ≥99%. CAS No. 85666-17-7. Molecular formula: C15H10NO3·Na. Mole weight: 275.2. |