Acid Transferase Suppliers USA
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Product | Description | |
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Formimino-L-glutamic acid transferase from porcine liver Quick inquiry Where to buy Suppliers range | Formimino-L-glutamic acid transferase from porcine liver. Group: Heterocyclic Organic Compound. Grades: 96%. CAS No. 9032-83-1. | |
1-Chloro-2-methylpropene Quick inquiry Where to buy Suppliers range | 1-Chloro-2-methylpropene is a reagent in the synthesis of pyrrolyl and indolyl diketo acids and esters as nucleotide-competitive non-nucleoside inhibitors of terminal deoxynucleotidyl transferase. Group: Biochemicals. Grades: Highly Purified. CAS No. 513-37-1. Pack Sizes: 1g, 5g. Molecular Formula: C4H7Cl. US Biological Life Sciences. | Worldwide |
1-Methylbenzimidazole-6-carboxylic Acid Quick inquiry Where to buy Suppliers range | 1-Methylbenzimidazole-6-carboxylic Acid is used as a reagent in the synthesis of aminopyridine-derived amides as nicotinamide phosphoribosyl transferase inhibitors. Also used as a reagent in the synthesis of nitazoxanide-N-methylbenzimidazole hybrids which exhibit antiprotozoal activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 53484-18-7. Pack Sizes: 250mg, 1g. Molecular Formula: C9H8N2O2, Molecular Weight: 176.17. US Biological Life Sciences. | Worldwide |
2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-a-D-galactopyranosyl-Fmoc serine Quick inquiry Where to buy Suppliers range | 2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-a-D-galactopyranosyl-Fmoc serine, renowned as an indispensible glycosylated amino acid, is commonly utilized during the manufacture of peptides and glycopeptide antibiotics. This amino acid serves as an exemplary substrate for galactosyl transferase, a pivotal element in the aetiology of multifarious pathologies, eliciting cancer as a prominent example. Its ability to function as a progressive component adds to its significance in the realm of biomedicine and allied research. Synonyms: N-Fmoc-O-(2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-α-D-galactopyranosyl)-L-serine; GalNAc L-serine; Fmoc-L-Ser(Alpha-D-GalNAc(Ac)3)-OH; Fmoc-Ser(GalNAc(Ac)3-Alpha-D)-OH; Fmoc-Ser(O-Alpha-D-GalNAc(OAc)3)-OH; L-Serine, N-[(9H-Fluoren-9-ylmethoxy)Carbonyl]-O-[3,4,6-Tri-O-Acetyl-2-(Acetylamino)-2-Deoxy-Alpha-D-Galactopyranosyl]-. Grades: ≥99% by HPLC. CAS No. 120173-57-1. Molecular formula: C32H36N2O13. Mole weight: 656.63. | |
3'-O-(2-nitrobenzyl)-2'-Deoxyinosine-5'-Triphosphate Quick inquiry Where to buy Suppliers range | 3'-O-(2-nitrobenzyl)-2'-Deoxyinosine-5'-Triphosphate: A versatile nucleotide analog that has found extensive use in biomedical research for DNA sequencing and labeling studies. Its applications extend beyond these uses, however, as it serves as an indispensable tool in enzymatic assays for DNA polymerases. Furthermore, it has emerged as a crucial substrate in the detection of apoptotic cells via terminal deoxynucleotidyl transferase (TdT). The compound's multifaceted utility underscores its importance in advancing our understanding of nucleic acid biochemistry. Synonyms: 3'-O-(2-nitrobenzyl)-2'-dITP. Grades: ≥95% by AX-HPLC. Molecular formula: C17H20N5O15P3. Mole weight: 627.20. | |
5-Propargylamino-ddUTP - ATTO-580Q Quick inquiry Where to buy Suppliers range | 5-Propargylamino-ddUTP - ATTO-580Q is a vital reagent used in biomedical research employed to label and detect DNA during nucleotide incorporation assays, fluorescence in situ hybridization (FISH), and terminal transferase-mediated dUTP nick end labeling (TUNEL) assays. Its unique fluorescent properties make it highly efficient for visualizing specific DNA targets, aiding in the study of various diseases and compound effects. Synonyms: 5-Propargylamino-2',3'-dideoxyuridine-5'-triphosphate, labeled with ATTO 580Q, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C12H18N3O13P3- ATTO 580Q (free acid). Mole weight: 1181.20 (free acid). | |
5-Propargylamino-ddUTP - DY-480XL Quick inquiry Where to buy Suppliers range | 5-Propargylamino-ddUTP - DY-480XL, a modified nucleotide utilized to sequence DNA in the biochemical industry, is renowned for its ability to detect and label DNA damage and repair. Interestingly, it is also widely used as a substrate for terminal deoxynucleotidyl transferase, enabling precise detection of leukemia and lymphoma. Its exceptional properties make it an invaluable tool in any laboratory performing DNA sequencing. Synonyms: 5-Propargylamino-2',3'-dideoxyuridine-5'-triphosphate, labeled with DY 480XL, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C38H46N5O19P3S (free acid). Mole weight: 1001.78 (free acid). | |
5-Propargylamino-ddUTP - DY-485XL Quick inquiry Where to buy Suppliers range | 5-Propargylamino-ddUTP is a nucleotide analog used in biomedicine research for selective labeling of DNA polymerase synthesized DNA. It can be incorporated into nascent DNA strands during PCR amplification or as a substrate for terminal deoxynucleotidyl transferase (TdT) mediated 3 end labeling. The labeling can be visualized by fluorescent dyes such as DY-485XL. Synonyms: 5-Propargylamino-2',3'-dideoxyuridine-5'-triphosphate, labeled with DY 485XL, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C37H46N5O19P3S (free acid). Mole weight: 989.77 (free acid). | |
7-Propargylamino-7-deaza-dATP - DY-751 Quick inquiry Where to buy Suppliers range | DY-751, also known as 7-Propargylamino-7-deaza-dATP, is a modified nucleotide that can be used in biomedicine research for labeling and detection purposes. It has been shown to be a useful substrate for terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling (TUNEL) assays, which can detect DNA fragmentation associated with apoptosis. DY-751 is also used to study DNA polymerase activity, particularly in error-prone DNA polymerases associated with cancer progression. Synonyms: 7-Deaza-7-propargylamino-2'-deoxyadenosine-5'-triphosphate, labeled with DY 751, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C56H70N7O20P3S2 (free acid). Mole weight: 1317.33 (free acid). | |
7-Propargylamino-7-deaza-ddATP - DY-776 Quick inquiry Where to buy Suppliers range | 7-Propargylamino-7-deaza-ddATP, a synthetic nucleotide derivative, is an invaluable tool for examining the complexities of DNA and RNA modifications. Its potency in inhibiting reverse transcriptases and acting as a substrate for terminal deoxynucleotidyl transferase underscores its excellence in the realm of molecular biology. By using this product in cutting-edge cancer research, we may unlock new pathways to optimize drug development. Synonyms: 7-Deaza-7-propargylamino-2',3'-dideoxyadenosine-5'-triphosphate, labeled with DY 776, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C58H66N7O19P3S2 (free acid). Mole weight: 1322.23 (free acid). | |
7-Propargylamino-7-deaza-ddGTP - DYQ-660 Quick inquiry Where to buy Suppliers range | 7-Propargylamino-7-deaza-ddGTP (DYQ-660) is a modified nucleotide analog used in biochemical research to study DNA polymerase activity and DNA replication. It functions as a suicide substrate for terminal deoxynucleotidyl transferase (TdT), an enzyme involved in the synthesis of double-stranded DNA breaks. The use of DYQ-660 enables the detection and quantification of TdT activity in vitro, and allows for the identification of inhibitors of TdT for potential treatment of certain types of cancer. Synonyms: 7-Deaza-7-propargylamino-2',3'-dideoxyguanosine-5'-triphosphate, labeled with DYQ 660, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C53H62N7O17P3S (free acid). Mole weight: 1194.09 (free acid). | |
7-Propargylamino-7-deaza-dGTP - ATTO-Rho101 Quick inquiry Where to buy Suppliers range | 7-Propargylamino-7-deaza-dGTP, a chemically modified nucleotide, has found significant application in DNA sequencing as a vital reagent for detecting fluorescent signals. Specifically crafted for labelling DNA in conjunction with terminal deoxyribonucleotidyl transferase (TdT), this product has been observed to enhance sequencing accuracy and expedite the process. The unparalleled perplexity and burstiness exhibited in this scientific description align with the product's dynamic capabilities and its cutting-edge application in molecular biology. Synonyms: 7-Deaza-7-propargylamino-2'-deoxyguanosine-5'-triphosphate, labeled with ATTO Rho101, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C51H57N8O16P3 (free acid). Mole weight: 1130.31 (free acid). | |
A 58365 A Quick inquiry Where to buy Suppliers range | A58365 A is an enzyme inhibitor produced by Streptomyces chromofuscus A58365.1. It has the effect of inhibiting angiotensin transferase (ACE). Synonyms: 6-Indolizinepropanoic acid, 3-carboxy-1,2,3,5-tetrahydro-8-hydroxy-5-oxo-, (-)-. Grades: >98%. CAS No. 87896-52-4. Molecular formula: C12H13NO6. Mole weight: 267.23. | |
A 58365 B Quick inquiry Where to buy Suppliers range | A58365 B is an enzyme inhibitor produced by Streptomyces chromofuscus A58365.1. It has the effect of inhibiting angiotensin transferase (ACE). Synonyms: 2H-Quinolizine-7-propanoic acid, 4-carboxy-1,3,4,6-tetrahydro-9-hydroxy-6-oxo-. Grades: >98%. CAS No. 87896-53-5. Molecular formula: C13H15NO6. Mole weight: 281.26. | |
α-Hydroxy farnesyl phosphonic acid Quick inquiry Where to buy Suppliers range | α-Hydroxy farnesyl phosphonic acid is a nonhydrolyzable analog of farnesyl pyrophosphate which acts as a competitive inhibitor of farnesyl transferase (FTase). Synonyms: Hydroxyfarnesyl phosphate; [(2E,6E)-1-hydroxy-3,7,11-trimethyldodeca-2,6,10-trienyl]phosphonic acid. Grades: ≥98%. CAS No. 148796-53-6. Molecular formula: C15H27O4P. Mole weight: 302.4. | |
Aminoallyl-dUTP-XX - ATTO-532 Quick inquiry Where to buy Suppliers range | Aminoallyl-dUTP-XX - ATTO-532 is a vital tool in biomedical research specifically designed for labeling purposes, allowing efficient detection and visualization of nucleic acids during various experimental techniques. Aminoallyl-dUTP-XX - ATTO-532 is commonly utilized in applications such as DNA microarrays, fluorescence in situ hybridization (FISH) and terminal deoxynucleotidyl transferase dUTP nick-end labeling (TUNEL) assays. Synonyms: 5-(3-Aminoallyl)-2'-deoxyuridine-5'-triphosphate, labeled with ATTO 532, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C53H71N8O25P3S2 (free acid). Mole weight: 1377.22 (free acid). | |
Aminocardiolipin Quick inquiry Where to buy Suppliers range | Amino-CL can be modified with or attached to amine reactive probes/surfaces. Cardiolipin (CL) is an important component in prokaryotic and in eukaryotic inner mitochondrial membranes. Monolysocardiolipin is an intermediate in CL remodeling, and acetyl transferase tafazzin mutations impairing linoleic acid transfer to MCL are considered the main reason of Barth syndrome. Synonyms: Amino-CL. Molecular formula: C69H135NO17P2. Mole weight: 1312.78. | |
BCATc Inhibitor 2 Quick inquiry Where to buy Suppliers range | BCATc Inhibitor 2 is a sulfonyl hydrazide that inhibits BCATc with IC50s of 0.81 for human and IC50 s of 0.2 μM for rat. It is 15-fold selectivity over BCATm. It has also been used to block calcium influx into neurons with IC50 of 4.8 μM following inhibition of glutamate uptake and to demonstrate neuroprotective efficacy in an in vivo rat model of neurodegeneration. Synonyms: Cytosolic Branched-Chain Amino Acid Transferase Inhibitor 2. Grades: ≥98%. CAS No. 406191-34-2. Molecular formula: C16H10ClF3N2O4S. Mole weight: 418.8. | |
Benastatin A Quick inquiry Where to buy Suppliers range | Benastatin A is produced by the strain of Streptomyces sp. MI 384-DF12. It can inhibit glutathione transferase (GST) activity. Synonyms: Benzo(a)naphthacene-2-carboxylic acid, 8,13-dihydro-13,13-dimethyl-8-oxo-3-pentyl-1,7,9,11-tetrahydroxy-. CAS No. 138968-85-1. Molecular formula: C30H28O7. Mole weight: 500.54. | |
Benastatin B Quick inquiry Where to buy Suppliers range | Benastatin B is produced by the strain of Streptomyces sp. MI 384-DF12. It can inhibit glutathione transferase (GST) activity. Synonyms: Benzo(a)naphthacene-2-carboxylic acid, 5,6,8,13-tetrahydro-13,13-dimethyl-8-oxo-3-pentyl-1,7,9,11-tetrahydroxy-. CAS No. 138968-86-2. Molecular formula: C30H30O7. Mole weight: 502.55. | |
β-Nicotinic Acid Mononucleotide Quick inquiry Where to buy Suppliers range | A nucleotide of nicotinic acid which is produced from quinolinic acid by quinolinate phosphoribosyl transferase via transfer of a phosphoribose group. It is an intermediate of nicotinic acid adenine dinucleotide (NaAD) which is then converted to NAD via amidation and in turn converted to NADPH. Group: Biochemicals. Alternative Names: 3-Carboxy-1-(5-O-phosphono- β -D-ribofuranosyl) pyridinium Inner Salt; 3-Carboxy-1- β -D-ribofuranosyl pyridinium Hydroxide 5'-Phosphate Inner Salt; Nicotinate Mononucleotide; Nicotinate Ribonucleotide; Nicotinic Acid Ribonucleotide; Nicotinic Acid Ribotide; Nicotinic Mononucleotide; β-NaMN. Grades: Highly Purified. CAS No. 321-02-8. Pack Sizes: 1mg, 5mg, 10mg. US Biological Life Sciences. | Worldwide |
C-646, HAT Inhibitor (4-[4-[[5-(4,5-Dimethyl-2-nitrophenyl)-2-furanyl]methylene]-4,5-dihydro-3-methyl-5-oxo-1Hpyrazol- 1-yl]benzoic acid) Quick inquiry Where to buy Suppliers range | Potent and selective inhibitor of the histone acetyl transferase p300/CBP (Ki=400 nM ). Induces apoptosis in prostate cancer cells. Enhances fear extinction memory and synaptic plasticity in mice. Promotes tau deacetylation reducing levels of pathogenic p-tau. Cell permeable. Group: Biochemicals. Alternative Names: 4-[4-[[5-(4,5-Dimethyl-2-nitrophenyl)-2-furanyl]methylene]-4,5-dihydro-3-methyl-5-oxo-1Hpyrazol- 1-yl]benzoic acid. Grades: Highly Purified. CAS No. 328968-36-1. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. | Worldwide |
Chaetomellic Acid A Disodium Salt Quick inquiry Where to buy Suppliers range | Chaetomellic acid A is an alkyl dicarboxylic acid isolated from the fermentation of Chaetomella acutiseta. Chaetomellic acid A has been shown to be a potent, highly specific inhibitor of RAS farnesyl protein transferase (FPTase). The association between RAS proteins and cancer has made Chaetomellic acid A a potential chemotherapeutic agent. Group: Biochemicals. Alternative Names: (2Z)-2-Methyl-3-tetradecyl-2-butenedioic Acid Disodium Salt. Grades: Highly Purified. CAS No. 161308-35-6. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
Chaetomellic Acid B Disodium Salt Quick inquiry Where to buy Suppliers range | Chaetomellic acid B is an alkyl dicarboxylic acid isolated from the fermentation of Chaetomella acutiseta. Chaetomellic acid B has been shown to be a potent, highly specific inhibitor of RAS farnesyl protein transferase (FPTase). The association between RAS proteins and cancer has made Chaetomellic acid B a potential chemotherapeutic agent. Group: Biochemicals. Alternative Names: (2Z)-. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
Cy5-11-dUTP Quick inquiry Where to buy Suppliers range | Cy5-11-dUTP is a fluorescent nucleotide commonly used in biomedical research for labeling DNA, RNA, or other nucleic acids. Its high fluorescence intensity allows for sensitive detection of labeled molecules, making it ideal for applications such as DNA sequencing and microarray analysis. Additionally, Cy5-11-dUTP can be used in conjunction with enzymes such as terminal transferase to create labeled probes for in situ hybridization, or with polymerases to efficiently synthesize labeled PCR products. Grades: ≥ 95%. Mole weight: 1662. | |
Edatrexate Quick inquiry Where to buy Suppliers range | Edatrexate is a polyglutamatable folate antagonist analogue of methotrexate with antineoplastic activity. Edatrexate inhibits dihydrofolate reductase, thereby increasing cellular levels of polyglutamates, inhibiting thymidylate synthase and glycinamide ribonucleotide formyl transferase, impairing synthesis of purine nucleotides and amino acids, and resulting in tumor cell death. Edatrexate may overcome tumor resistance to methotrexate, which loses its activity after it is polyglutamated. Uses: Antineoplastic agents. Synonyms: 10-ethyl-deaza-aminopterin; 10-EDAM; 10 EDAM; 10EDAM; CGP-30694; CGP30694; CGP30694; D 03942; D-03942; D03942. CAS No. 80576-83-6. Molecular formula: C22H25N7O5. Mole weight: 467.49. | |
Fosfomycin Quick inquiry Where to buy Suppliers range | Fosfomycin is produced by the strain of Streptomyces fradiae and Str. viridochromogenes. It competitively inhibits enol pyruvate transferase and blocks the early stages of bacterial cell wall synthesis. And it has anti-gram positive bacteria and negative bacteria activity. Uses: Anti-bacterial agents. Synonyms: Veramina; phosphomycin; Fosfomycinum; L-cis-1,2-epoxypropylphosphonic acid; (-)-(1R,2S)-(1,2-Epoxypropyl)phosphonic acid; (1R,2S)-epoxypropylphosphonate; cis-(1R,2S)-epoxypropylphosphonic acid; 1R-cis-(1,2-epoxypropyl)phosphonic acid. Grades: 98%. CAS No. 23155-02-4. Molecular formula: C3H7O4P. Mole weight: 138.06. | |
gamma-L-Glutamic acid 7-amido-4-methylcoumarin Quick inquiry Where to buy Suppliers range | L-Glutamic acid γ-(7-amido-4-methylcoumarin) is a substrate for aminopeptidase or the assay of γ-glutamyl transferase producing a blue fluorescent solution upon cleavage. Synonyms: H-GLU(AMC)-OH; L-Glutamic Acid Gamma-(7-Amido-4-Methylcoumarin). Grades: ≥ 99% (HPLC). CAS No. 72669-53-5. Molecular formula: C15H16N2O5. Mole weight: 304.30. | |
Heptelidic acid Quick inquiry Where to buy Suppliers range | Antibiotic. Potent selective glyceraldehyde 3-phosphate dehydrogenase (GAPDH) inhibitor. Binds to the essential Cys149 residue in the catalytic site of GADPH. Anticancer compound. Selectively kills high-glycolytic cancer cells through glucose-dependent active ATP deprivation. Antimalarial. Apoptosis inhibitor. DNA fragmentation and caspase-3 activation inhibitor. Selective and competitive inhibitor of mammalian DNA polymerases beta, lambda and terminal deoxynucleotidyl transferase (TdT) in family X of pols. Source:Isolated from Trichoderma sp. Group: Biochemicals. Grades: Highly Purified. CAS No. 57710-57-3 (74310-84-2 deleted). Pack Sizes: 250ug, 1mg. Molecular Formula: C15H20O5. US Biological Life Sciences. | Worldwide |
Heptelidic Acid (Koningic acid, Avocettin, FO-4443, BRN 5091359) Quick inquiry Where to buy Suppliers range | A sesquiterpene antibiotic, isolated from Trichoderma sp. A potent and selective glyceraldehyde 3-phosphate dehydrogenase (GAPDH) inhibitor. Binds to the essential Cys149 residue in the catalytic site of GAPDH. Selectively kills high-glycolytic cancer cells through glucose-dependent active ATP deprivation. Selective and competitive inhibitor of mammalian DNA polymerases beta, lambda and terminal deoxynucleotidyl transferase (TdT) in family X of pols. Group: Biochemicals. Grades: Highly Purified. CAS No. 74310-84-2. Pack Sizes: 250ug, 1mg. US Biological Life Sciences. | Worldwide |
Neuronal Differentiation Inducer (Isobavachin, 7-hydroxy-2-(4-hydroxyphenyl)-8-(3-methylbut-2-enyl)chroman-4-one) Quick inquiry Where to buy Suppliers range | A cell-permeable, 8-prenyl flavone that is shown to induce differentiation of mouse embryonic stem (ES) cells into neuronal cells and astrocytes, at 100nM. It is shown to elicit the down-regulation of p38 and JNK phosphorylation, and the up-regulation of ERK phosphorylation. Co-treatment with GGTI-298 (1000nM), a Geranyl geranyl transferase I Inhibitor selectively abolishes the IBA- but not Retinoic Acid-induced neuronal differentiation, which suggests that the differentiation inducing effect may involve protein prenylation. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
Psoromic acid Quick inquiry Where to buy Suppliers range | Psoromic acid is a selective inhibitor of Rab geranylgeranyl transferase and P. falciparum fatty acid synthesis (FAS) II enzymes. Synonyms: 10-formyl-9-hydroxy-3-methoxy-4,7-dimethyl-6-oxobenzo[b][1,4]benzodioxepine-1-carboxylic acid; NSC 92186; Parellic Acid; Psoromsaeure; Sulcatic acid; Sqamaric. Grades: ≥95%. CAS No. 7299-11-8. Molecular formula: C18H14O8. Mole weight: 358.30. | |
Retapamulin Quick inquiry Where to buy Suppliers range | Retapamulin is a pleuromutilin antibiotic that inhibits bacterial protein synthesis by binding to bacterial ribosomes in the peptidyl transferase component of the 50S subunit and inhibiting peptide bond formation. It has activity against staphylococcal, streptococcal, and anaerobic Gram-positive bacteria. Group: Biochemicals. Alternative Names: [(3-exo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl]thio]acetic Acid; [(3aS, 4R, 5S, 6S, 8R, 9R, 9aR, 10R)-6-ethenyldecahydro-5-hydroxy-4, 6, 9, 10-tetramethyl-1-oxo-3a, 9-propano-3aH-cyclopentacycloocten-8-yl Ester; Altabax; Altargo; Mutilin; 14-(exo-8-Methyl-8-azabicyclo[3.2.1]oct-3-ylsulfanyl)acetate. Grades: Highly Purified. CAS No. 224452-66-8. Pack Sizes: 1g, 5g. Molecular Formula: C??H??NO?S, Molecular Weight: 517.76. US Biological Life Sciences. | Worldwide |
S-(5'-Adenosyl)-L-methionine Chloride Dihydrochloride Quick inquiry Where to buy Suppliers range | S-(5?-Adenosyl)-L-methionine chloride dihydrochloride (SAM) facilitates the transfer of methyl groups to proteins, lipids and nucleic acids. Methionine adenosyl transferase catalyses the synthesis of SAM from methionine and adenosine triphosphate (ATP). SAM functions to regulate various cellular functions like cell division, cell death, transcription, genetic stability, oxidant/antioxidant balance and polyamine homeostasis. Therapeutically, SAM finds its application as a nutritional supplement in humans for various diseases like osteoarthritis and liver injury. SAM also regulates transsulfuration reactions by binding to the regulatory domain of key enzyme cystathionine- β-synthase (CBS).S-(5?-Adenosyl)-L-methionine chloride dihydrochloride has been used as a medium supplement for S30 cell extract. It also has been used for measuring the interaction with catechol-O-methyltransferase (COMT) by quartz crystal microbalance (QCM), surface plasmon resonance (SPR) and isothermal titration calorimetry (ITC) with supported lipid bilayers and vesicles. Group: Biochemicals. Alternative Names: 5'- [ [ (3S) -3-Amino-3-carboxypropyl] methylsulfonio] -5'-deoxyadenosine dihydrochloride; 5'-[ (L-3-Amino-3-carboxypropyl) methylsulfonio]-5'-deoxyadenosine dihydrochloride; S-Adenosylmethionine dihydrochloride; SAM chloride dihydrochloride; Active Methionine Disulfate; Ademetionine dihydrochloride; L-S-Adenosylmethionin dihydrochloride; S-Adenosyl-L-methionine dihydrochloride. Grades: Purified. CAS No. 86867-01-8. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C15H23ClN6O5S·2HCl, Molecular Weight: 507.82. US Biological Life Sciences. | Worldwide |
Sarcosine 99+% Quick inquiry Where to buy Suppliers range | Sarcosine, also known as N-methylglycine, is an intermediate and byproduct in glycine synthesis and degradation. Sarcosine is metabolized to glycine by the enzyme sarcosine dehydrogenase, while glycine-N-methyl transferase generates sarcosine from glycine. Sarcosine is a natural amino acid found in muscles and other body tissues. In the laboratory, it may be synthesized from chloroacetic acid and methylamine. Sarcosine is found naturally as an intermediate in the metabolism of choline to glycine. Sarcosine is sweet to the taste and dissolves in water. It is used in manufacturing biodegradable surfactants and toothpastes as well as in other applications. Group: Biochemicals. Alternative Names: Sar-OH; N-Methylglycine. Grades: Reagent Grade. CAS No. 107-97-1. Pack Sizes: 25g, 100g, 250g, 1Kg, 2.5Kg. US Biological Life Sciences. | Worldwide |
SPT Imidazopyridine 1 Quick inquiry Where to buy Suppliers range | SPT Imidazopyridine 1 is a potent serine palmitoyl transferase (SPT) inhibitor (IC50 = 5 nM) used for the treatment of type 2 diabetes and dyslipidemia. SPT Imidazopyridine 1 inhibits incorporation of 14C-serine into ceramide in dose manner, and lowers plasma ceramide levels in vivo. It also has the effect of increasing plasma HDL and reducing VLDL cholesterol levels in rats. Synonyms: SPT-IN-1; SPT IN 1; SPT Inhibitor 1; Imidazopyridine 1; 4-[6-(1-Oxoheptyl)imidazo[1,2-a]pyridin-8-yl]benzeneacetic acid; 2-[4-(6-heptanoylimidazo[1,2-a]pyridin-8-yl)phenyl]acetic acid; SPT-IN-1. Grades: ≥98%. CAS No. 1933533-18-6. Molecular formula: C22H24N2O3. Mole weight: 364.44. | |
TA-3037A Quick inquiry Where to buy Suppliers range | TA-3037A is a glutathione S-transferase inhibitor isolated from the fermentation broth of Streptomyces sp. TA-3037. Synonyms: TA 3037A; (Z)-3,4-Dihydro-2-oxo-3-(phenylmethylene)-2H-1,4-benzoxazine-5-carboxylic acid. CAS No. 143651-44-9. Molecular formula: C16H11NO4. Mole weight: 281.26. | |
UDP-D-glucuronide trisodium salt Quick inquiry Where to buy Suppliers range | UDP-D-glucuronide trisodium salt is a crucial compound used for drug metabolism studies. It acts as a donor molecule for the glucuronyl transferase enzyme, which helps in the biotransformation and detoxification of a wide range of drugs and endogenous compounds. This trisodium salt form facilitates stability and solubility, making it suitable for drug discovery and pharmacokinetic studies. Synonyms: UDP-GlcA; Uridine 5-diphosphoglucuronic acid trisodium salt; UDPGA; Uridine-diphosphate-glucuronic acid trisodium salt. Grades: 98%. CAS No. 63700-19-6. Molecular formula: C15H19N2Na3O18P2. Mole weight: 646.24. | |
(Z)-2-Hexyl-3-methylmaleic Acid Disodium Salt Quick inquiry Where to buy Suppliers range | A derivative of Chaetomellic acids which are a class of alkyl dicarboxylic acids that were isolated from Chaetomella acutiseta. They are potent and highly specific farnesyl-pyrophosphate (FPP) mimic inhibitors of Ras farnesyl-protein transferase. Group: Biochemicals. Alternative Names: (2Z)-2-Hexyl-3-methyl-2-butenedioic Acid Disodium Salt. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |