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| Product | Description | |
|---|---|---|
| 2-Cyanomethylthioadenosine | 2-Cyanomethylthioadenosine, a powerful inhibitor of S-adenosylhomocysteine hydrolase (SAHH), the regulator of methylation pressure and a participant in the development of cancer, is a highly effective modulator of extracellular metabolism, opening doors for therapeutic interventions in cancer, inflammation, and immunomodulation, illuminating its status as a multifaceted agent at the cutting-edge of biochemistry. Grades: ≥95%. CAS No. 2095417-67-5. Molecular formula: C12H14N6O4S. Mole weight: 338.34. |  |
| 3-Deazaadenosine | 3-Deazaadenosine is an inhibitor of S-adenosylhomocysteine hydrolase, with a Ki of 3.9 μM; 3-Deazaadenosine has anti-inflammatory, anti-proliferative and anti-HIV activity. Group: Inhibitors. CAS No. 6736-58-9. Molecular formula: C11H14N4O4. Mole weight: 266.25. Appearance: Solid. Canonical SMILES: O[C@H]1[C@@H] (O[C@H] (CO)[C@H]1O)N2C3=C (C (N)=NC=C3)N=C2. Catalog: ACM6736589. |  |
| 3-Deazaadenosine | 3-Deazaadenosine is an inhibitor of S-adenosylhomocysteine hydrolase , with a K i of 3.9 μM; 3-Deazaadenosine has anti-inflammatory, anti-proliferative and anti- HIV activity. Uses: Scientific research. Group: Signaling pathways. CAS No. 6736-58-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-W013332. |  |
| 3-Deazaadenosine hydrochloride | 3-Deazaadenosine (hydrochloride) is an inhibitor of S-adenosylhomocysteine hydrolase , with a K i of 3.9 μM; 3-Deazaadenosine has anti-inflammatory, anti-proliferative and anti- HIV activity. Uses: Scientific research. Group: Signaling pathways. CAS No. 86583-19-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-W013332A. | |
| 3-Deazaneplanocin A | 3-Deazaneplanocin A (DZNep) is a potent histone methyltransferase EZH2 inhibitor [1] [2]. 3-Deazaneplanocin A is a potent S-adenosylhomocysteine hydrolase (AHCY) inhibitor. 3-Deazaneplanocin A shows anti-orthopoxvirus activity [6] [7]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DZNep; 3-Deazaneplanocin. CAS No. 102052-95-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-10442. | |
| 3-Deazaneplanocin A | 3-Deazaneplanocin A is a a powerful inhibitor of S-adenosylhomocysteine hydrolase that has shown potent and selective in vitro and in vivo antiviral activities. Group: Biochemicals. Alternative Names: (1S,2R,5R)-5-(4-Amino-1H-imidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)-3-cyclopentene-1,2-diol Hydrochloride;[1S-(1α,2α,5 β)]-5-(4-Amino-1H-imidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)-3-cyclopentene-1,2-diol Monohydrochloride. Grades: Highly Purified. CAS No. 120964-45-6. Pack Sizes: 500ug, 1mg, 5mg. Molecular Formula: C??H??ClN?O?, Melting Point: >185°C (dec.). US Biological Life Sciences. |  Worldwide |
| 3-deazaneplanocin A (DZNeP) HCl | 3-deazaneplanocin A (DZNeP)HCl, an analog of adenosine, is a competitive inhibitor of S-adenosylhomocysteine hydrolase with Ki of 50 pM. Synonyms: NSC 617989 HCl; NSC617989 HCl; NSC-617989 HCl; 3-deazaneplanocin A HCl; 3-deazaneplanocin A hydrochloride; DZNep. Grades: >98%. CAS No. 120964-45-6. Molecular formula: C12H15ClN4O3. Mole weight: 298.72. | |
| 3-Deazaneplanocin A hydrochloride | 3-Deazaneplanocin A hydrochloride (DZNep hydrochloride) is a potent histone methyltransferase EZH2 inhibitor [1] [2]. 3-Deazaneplanocin A hydrochlorideis a potent S-adenosylhomocysteine hydrolase (AHCY) inhibitor [6]. 3-Deazaneplanocin A hydrochloride also has anti- orthopoxvirus and anti-variola activities [7]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DZNep hydrochloride; NSC 617989 hydrochloride; 3-Deazaneplanocin hydrochloride. CAS No. 120964-45-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12186. | |
| 8-Fluoroadenosine | 8-Fluoroadenosine is an extraordinary compound, acting as a highly selective inhibitor of S-adenosylhomocysteine hydrolase (SAHH) within the dynamic realm of cellular biochemistry. Synonyms: 8-fluoro-adenosine; (2R,3R,4S,5R)-2-(6-Amino-8-fluoro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol. CAS No. 23205-67-6. Molecular formula: C10H12FN5O4. Mole weight: 285.23. | |
| Adenosine dialdehyde | Adenosine dialdehyde is an irreversible inhibitor of S-adenosylhomocysteine hydrolase (IC50 = 40 nM), blocking the conversion of SAH to homocysteine and adenosine. Synonyms: 2-[1-(6-aminopurin-9-yl)-2-oxoethoxy]-3-hydroxypropanal. Grades: ≥ 95 %. CAS No. 34240-05-6. Molecular formula: C10H11N5O4. Mole weight: 265.23. | |
| adenosylhomocysteinase | The enzyme contains one tightly bound NAD+ per subunit. This appears to bring about a transient oxidation at C-3' of the 5'-deoxyadenosine residue, thus labilizing the thioether bond (for mechanism, click here), cf. EC 5.5.1.4, inositol-3-phosphate synthase. Group: Enzymes. Synonyms: S-adenosylhomocysteine synthase; S-adenosylhomocysteine hydrolase (ambiguous); adenosylhomocysteine hydrolase; S-adenosylhomocysteinase; SAHase; AdoHcyase. Enzyme Commission Number: EC 3.3.1.1. CAS No. 9025-54-1. AHCY. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3992; adenosylhomocysteinase; EC 3.3.1.1; 9025-54-1; S-adenosylhomocysteine synthase; S-adenosylhomocysteine hydrolase (ambiguous); adenosylhomocysteine hydrolase; S-adenosylhomocysteinase; SAHase; AdoHcyase. Cat No: EXWM-3992. |  |
| Adenosylhomocysteinease from Human, Recombinant | S-adenosylhomocysteine hydrolase belongs to the adenosylhomocysteinase family. It catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). Thus, it regulates the intracellular S-adenosylhomocysteine (SAH) concentration thought to be important for transmethylation reactions. Deficiency in this protein is one of the different causes of hypermethioninemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Adenosylhomocysteinase is an enzyme that converts S-adenosylhomocysteine to homocysteine and adenosine. This enzyme catalyses the following chemical reaction: S-adenosyl-L-homocysteine + H2O<-> L-homocysteine + adenosine. The enzyme contains one tightly bound NAD+ per subunit. Group: Enzymes. Synonyms: Adenosylhomocysteinase; S-adenosylhomocysteine synthase; S-adenosylhomocysteine hydrolase; adenosylhomocysteine hydr. Enzyme Commission Number: EC 3.3.1.1. CAS No. 9025-54-1. AHCY. Mole weight: 47 kDa. Storage: -20°C. Form: Purified and lyophilized powder or Purified, solution in 50% glycerol. Source: Human. Adenosylhomocysteinase; S-adenosylhomocysteine synthase; S-adenosylhomocysteine hydrolase; adenosylhomocysteine hydrolase ambiguous; S-adenosylhomocysteinase; SAHase; AdoHcyase; EC 3.3.1.1; 9025-54-1; AHCY. Cat No: DIA-122. | |
| adenosylhomocysteine nucleosidase | Also acts on S-methyl-5'-thioadenosineto give adenine and S-methyl-5-thioribose (cf. EC 3.2.2.16, methylthioadenosine nucleosidase). Group: Enzymes. Synonyms: S-adenosylhomocysteine hydrolase (ambiguous); S-adenosylhomocysteine nucleosidase; 5'-methyladenosine nucleosidase; S-adenosylhomocysteine/5'-methylthioadenosine nucleosidase; AdoHcy/MTA nucleosidase. Enzyme Commission Number: EC 3.2.2.9. CAS No. 9055-10-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3991; adenosylhomocysteine nucleosidase; EC 3.2.2.9; 9055-10-1; S-adenosylhomocysteine hydrolase (ambiguous); S-adenosylhomocysteine nucleosidase; 5'-methyladenosine nucleosidase; S-adenosylhomocysteine/5'-methylthioadenosine nucleosidase; AdoHcy/MTA nucleosidase. Cat No: EXWM-3991. | |
| D-Eritadenine | D-Eritadenine is an adenosine analog and a potent, reversible inhibitor of S-adenosylhomocysteine hydrolase. Dietary administration of D-eritadenine (50 mg/kg) increases liver microsomal phosphatidylethanolamine concentration and decreases liver microsomal Δ6 desaturase activity and plasma cholesterol levels in rats. Uses: Enzyme inhibitors. Synonyms: (αR,βR)-6-Amino-α,β-dihydroxy-9H-purine-9-butanoic Acid; 4-(6-Amino-9H-purin-9-yl)-4-deoxy-D-erythronic Acid; 4-(6-Aminopurin-9-yl)-4-deoxy-D-erythronic Acid; Lentinacin; Lentysine; 4-(9-Adenyl)-D-erythro-2,3-dihydroxybutyric Acid; Eritadenine; Lentysine; Lentinacin. Grades: ≥95%. CAS No. 23918-98-1. Molecular formula: C9H11N5O4. Mole weight: 253.21. | |
| Native Rabbit S-(5'-Adenosyl)-L-homocysteine Hydrolase | Enzyme in vertebrates which catabolizes S-adenosyl-L-homocysteine. Group: Enzymes. Synonyms: Adenosylhomocysteinase; EC 3.3.1.1; S-adenosylhomocysteine synthase; S-adenosylhomocysteine hydrolase; adenosylhomocysteine hydrolase (ambiguous); S-adenosylhomocysteinase; SAHase; AdoHcyase; 9025-54-1. Enzyme Commission Number: EC 3.3.1.1. CAS No. 9025-54-1. AHCY. Activity: > 10 units/mg protein (Lowry). Storage: -70°C. Form: buffered aqueous glycerol solution; Solution in 25 mM Tris, pH 7.4, containing 1 mM dithiothreitol, 1 mM EDTA, and 20% glycerol. Source: Rabbit erythrocytes. Species: Rabbit. Adenosylhomocysteinase; EC 3.3.1.1; S-adenosylhomocysteine synthase; S-adenosylhomocysteine hydrolase; adenosylhomocysteine hydrolase (ambiguous); S-adenosylhomocysteinase; SAHase; AdoHcyase; 9025-54-1. Cat No: NATE-0662. | |
| S-adenosylhomocysteine deaminase | This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amidines. Group: Enzymes. Synonyms: adenosylhomocysteine deaminase. Enzyme Commission Number: EC 3.5.4.28. CAS No. 125149-24-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4555; S-adenosylhomocysteine deaminase; EC 3.5.4.28; 125149-24-8; adenosylhomocysteine deaminase. Cat No: EXWM-4555. | |
| S-Adenosyl-L-Homocysteine Hydrolase, Recombinant | Enzyme in vertebrates which catabolizes S-adenosyl-L-homocysteine. S-adenosyl-l-homocysteine hydrolase (sahh, ec 3.3.1.1) (adohcyase) is an enzyme of the activated methyl cycle, responsible for the reversible hydration of s-adenosyl-l-homocysteine into adenosine and homocysteine. sahh is a ubiquitous enzyme which binds and requires nad+ as a cofactor. adohcyase is a highly conserved protein of about 430 to 470 amino acids. the family contains a glycine-rich region in the central part of adohcyase; aregion thought to be involved in nad-binding. this protein may use themorpheein model of allosteric regulation. Group: Enzymes. Synonyms: Adenosylhomocysteinase; EC 3.3.1.1; S-adenosylhomocysteine synthase; S-adenosylhomocysteine hydrolase; adenosylhomocysteine hydrolase (ambiguous); S-adenosylhomocyste. Enzyme Commission Number: EC 3.3.1.1. Purity: >90% (SDS-PAGE test). Mole weight: About 44kDa (SDS-PAGE detection). Activity: 140U/mg. Appearance: White powder, lyophilized. Storage: Redissolved in 20% glycerol, 4°C, store at -20°C for long-term preservation, Avoid multiple freeze-thaw cycles. Form: Freeze dried powder. Adenosylhomocysteinase; EC 3.3.1.1; S-adenosylhomocysteine synthase; S-adenosylhomocysteine hydrolase; adenosylhomocysteine hydrolase (ambiguous); S-adenosylhomocysteinase; SAHase; AdoHcyase; 9025-54-1. Cat No: NATE-1150. | |
| Ilimaquinone | Cytoplasmic microtubule inhibitor. Cell permeable, antimicrobial, anti-inflammatory, antimitotic and cytotoxic compound. Induces a complete and reversible breakdown/disruption of Golgi membranes into smaller vesicular structures. Blocks the association of the ADP-ribosylation factor and beta-COP to the Golgi membrane. Blocks protein transport to the plasma membrane and inhibits gap junctional communication. HIV-1 inhibitor. Blocks the cytotoxicity of ricin and diphtheria toxin. S-Adenosylhomocysteinase hydrolase inhibitor and cellular methylations inhibitor. DNA polymerase beta lyase activity inhibitor. Anti-cancer compound. Source:Isolated from Anthelia sp. Group: Biochemicals. Grades: Highly Purified. CAS No. 71678-03-0. Pack Sizes: 100ug. Molecular Formula: C22H30O4. US Biological Life Sciences. | Worldwide |
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