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| Product | Description | |
|---|---|---|
| ALK inhibitor 1 | ALK inhibitor 1 is a novel and selective inhibitor for the ALK kinase. Synonyms: Benzenesulfonamide, 2-[[5-bromo-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]amino]-N-methyl-. Grades: >98%. CAS No. 761436-81-1. Molecular formula: C23H28BrN7O3S. Mole weight: 562.48. |  |
| ALK inhibitor 2 | ALK inhibitor 2 is a novel and selective inhibitor for the ALK kinase. Synonyms: Benzenesulfonamide, 2-[[5-chloro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]amino]-N-methyl-. Grades: >98%. CAS No. 761438-38-4. Molecular formula: C23H28ClN7O3S. Mole weight: 518.03. | |
| Alk 5 Inhibitor II | Alk 5 Inhibitor II. Group: Biochemicals. Alternative Names: 2-[3-(6-Methyl-2-pyridinyl)-1H-pyrazol-4-yl]-1,5-naphthyridine; E 616452; RepSox; SJN 2511. Grades: Highly Purified. CAS No. 446859-33-2. Pack Sizes: 10mg. Molecular Formula: C17H13N5, Molecular Weight: 287.32. US Biological Life Sciences. |  Worldwide |
| ALK5 Inhibitor II hydrochloride | ALK5 inhibitor II was identified as a cell permeable, selective inhibitor of the TGF-β type 1 activin like kinase receptor ALK5 (ALK5 autophosphorylation, IC50s = 4 nM, TGF-β cellular assay, IC50s = 18 nM, ALK5 binding in HepG2 cells, IC50s = 23 nM). This compound has been used to induce stem cell pluripotency by replacing the reprogramming transcription factor Sox2 via inhibition of the TGF-β signaling pathway and induction of Nanog transcription. This product is a hydrochloride form. Synonyms: E 616452; RepSox; SJN 2511. Grades: ≥98%. CAS No. 446859-33-2. Molecular formula: C17H13N5·HCl. Mole weight: 323.8. | |
| BMP Inhibitor II, DMH1 (ALK2/3 Inhibitor, DMH1, Bone Morphogenetic Protein Inhibitor, DMH1, 4- (6- (4-Isopropoxyphenyl) pyrazolo[1, 5-a]pyrimidin-3-yl) quinoline) | A cell-permeable pyrrazolopyrimidine compound that inhibits against R/VEGFR2, ALK2/BMPR-I, AMPK kinase activity (IC50=25.1, 148, and 234.6nM, respectively), while exhibiting much reduced or little effect toward ALK5/TGFbR-I, ZAPK, Syk, PKCth, PKA, or JAK3. Shown to block both BMP pathway-dependent dorsoventral development (EC100=2.5uM) and VEGF signaling-dependent intersomitic vessel formation (EC50=5uM) in zebrafish embryo in vivo. Commonly used in combination with AMPK activators AICAR and/or Metformin for studying AMPK-dependent cellular events in vitro and physiological responses in animals in vivo. Group: Biochemicals. Grades: Highly Purified. CAS No. 1206711-16-1. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| 10Z-Hymenialdisine | 10Z-Hymenialdisine ((Z)-Hymenialdisine) is a natural bioactive pyrrole alkaloid. 10Z-Hymenialdisine is a pan kinase inhibitor, and has anticancer activities [1]. Uses: Scientific research. Group: Natural products. Alternative Names: (Z)-Hymenialdisine; Hymenialdisine. CAS No. 82005-12-7. Pack Sizes: 500 μg. Product ID: HY-N6794. |  |
| 1,1,2-Triethoxyethane | 1,1,2-Triethoxyethane is an intermediate used to synthesize pyrazolopyrimidine derivatives as COX-2 selective inhibitors. It is also used to prepare [ (1, 2, 4-oxadiazolylphenoxy) alkyl]isoxazoles as antiviral agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 4819-77-6. Pack Sizes: 1g, 5g. Molecular Formula: C8H18O3, Molecular Weight: 162.229999999999. US Biological Life Sciences. | Worldwide |
| 11-Aminoundecanoic acid | 11-Aminoundecanoic Acid is used to prepare thapsigargin analogues targeting apoptosis to prostatic cancer cells. It is also used to synthesize N-carboxyalkylpeptides containing extended alkyl residues at P1'as matrix metalloproteinase inhibitors. Synonyms: ω-Aminoundecanoic acid; Undecanoic acid, 11-amino-; 11-Aminoundecylic acid; 11-amino-undecanoic acid; H-11-Aun-OH. Grades: ≥ 99% (Titration). CAS No. 2432-99-7. Molecular formula: C11H23NO2. Mole weight: 201.31. | |
| 1- (2, 4-Dihydroxy-5-isopropylphenyl) ethanone | 1- (2, 4-Dihydroxy-5-isopropylphenyl) ethanone acts as a reagent in the synthesis of 3,5-disubstituted-4-alkynylisoxozales as HSP90 inhibitors against various human cancer cell lines. Group: Biochemicals. Grades: Highly Purified. CAS No. 747414-17-1. Pack Sizes: 250mg, 500mg. Molecular Formula: C11H14O3, Molecular Weight: 194.23. US Biological Life Sciences. | Worldwide |
| 1,2-Dimethyl-hydrazine Dihydrochloride | 1,2-Dimethylhydrazine is a potent carcinogen that acts as a DNA alkylating agent. It is used to induce colon tumors in experimental animals. It was also used in preparation of spiroisoquinolinedione aldose reductase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 306-37-6. Pack Sizes: 2.5g, 5g. Molecular Formula: C2H10Cl2N2, Molecular Weight: 133.02. US Biological Life Sciences. | Worldwide |
| 1-(3,4-Dihydroxyphenyl)-2-(3-ethyl-1H-pyrazol-1-yl)ethanone Hydrochloride | 1-(3,4-Dihydroxyphenyl)-2-(3-ethyl-1H-pyrazol-1-yl)ethanone Hydrochloride is a biochemical inhibitor of placental alkaline phosphatase (PLAP) and is used to elucidate the key biological functions and natural substrates of human PLAP. Group: Biochemicals. Grades: Highly Purified. CAS No. 1135318-57-8. Pack Sizes: 1mg, 5mg. Molecular Formula: C13H15ClN2O3, Molecular Weight: 282.72. US Biological Life Sciences. | Worldwide |
| 1,3,9-Trimethyluric Acid | 1,3,9-Trimethyluric Acid has been found in rat urine as a metabolite of Caffeine (C080100), a bitter, white crystalline xanthine alkaloid that acts as a stimulant drug and a reversible acetylcholinesterase inhibitor. Caffeine is found in varying quantities in the seeds, leaves, and fruit of some plants, where it acts as a natural pesticide that paralyzes and kills certain insects feeding on the plants. Group: Biochemicals. Grades: Highly Purified. CAS No. 7464-93-9. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C8H10N4O3, Molecular Weight: 210.19. US Biological Life Sciences. | Worldwide |
| 1-(3-Chloro-2-methylpropyl)-4-methylpiperazine Dihydrochloride | 1-(3-Chloro-2-methylpropyl)-4-methylpiperazine Dihydrochloride is used as a reagent in the synthesis of (phenylmethylene) alkoxyimino cycloalkanes as ulcer- and gastric acid secretion inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 102449-98-9. Pack Sizes: 500mg, 5g. Molecular Formula: C9H21Cl3N2, Molecular Weight: 263.64. US Biological Life Sciences. | Worldwide |
| 1-(3-Chloropropoxy)-4-fluorobenzene | 1-(3-Chloropropoxy)-4-fluorobenzene was used as a reagent in the preparation of a library of hydantoin compds which has used to study Aurora kinase A inhibitory activity. It was also used as an alkylation agent in the preparation of tetracyclic quinoxaline butyrophenones as 5-HT2A and postsynaptic D2 antagonists and inhibitors of serotonin transporter for treatment of neuropsychiatric and neurological disorders. Group: Biochemicals. Grades: Highly Purified. CAS No. 1716-42-3. Pack Sizes: 1g, 5g. Molecular Formula: C9H10ClFO, Molecular Weight: 188.63. US Biological Life Sciences. | Worldwide |
| 1-(5-Amino-2-hydroxyphenyl)ethanone | 1-(5-Amino-2-hydroxyphenyl)ethanone is used in the preparation of alkylated flavonoid compounds for use as therapeutic antioxidants. It is also used to synthesize spiro[chromanone-piperidine]s as acetyl-CoA carboxylase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 50-80-6. Pack Sizes: 50mg, 100mg. Molecular Formula: C8H9NO2, Molecular Weight: 151.16. US Biological Life Sciences. | Worldwide |
| 1-(5-Fluoro-2-iodophenyl)ethanone | 1-(5-Fluoro-2-iodophenyl)ethanone is a reactant in the preparation of PF-06463922, a potent macrocyclic ALK inhibitor as potential antitumor. Group: Biochemicals. Grades: Highly Purified. CAS No. 914225-70-0. Pack Sizes: 1g, 2.5g. Molecular Formula: C8H6FIO, Molecular Weight: 264.04. US Biological Life Sciences. | Worldwide |
| 1,7,9-Trimethyluric Acid | 1,7,9-Trimethyluric Acid is an intermediate in the synthesis of Methylliberine (M315730), an alkaloid metabolite of Caffeine (C080100), a bitter, white crystalline xanthine alkaloid that acts as a stimulant drug and a reversible acetylcholinesterase inhibitor. Caffeine is found in varying quantities in the seeds, leaves, and fruit of some plants, where it acts as a natural pesticide that paralyzes and kills certain insects feeding on the plants. Group: Biochemicals. Grades: Highly Purified. CAS No. 55441-64-0. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C8H10N4O3, Molecular Weight: 210.19. US Biological Life Sciences. | Worldwide |
| 17-ODYA | 17-Octadecynoic acid is a suicide inhibitor of LTB4 ω-oxidase. 17-ODYA can completely inhibit the bradykinin-dependent transport of sodium chloride in rat TALH cells at a concentration of 10 μM. Synonyms: Alkynyl Stearic Acid;17-Octadecynoic acid. Grades: ≥98% by HPLC. CAS No. 34450-18-5. Molecular formula: C18H32O2. Mole weight: 280.45. | |
| 17-ODYA | 17-ODYA is a CYP450 ω-hydroxylase inhibitor. 17-ODYA is also a potent inhibitor (IC 50 <100 nM) of the formation of 20-hydroxyeicosatetraenoic acid (20-HETE), epoxyeicosatrienoic acids and dihydroxyeicosatrienoic acids by rat renal cortical microsomes incubated with arachidonic acid. 17-ODYA completely attenuates the isoproterenol (ISO)-induced apoptosis, and necrosis in cultured cardiomyocytes [1] [2] [3]. 17-ODYA is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 34450-18-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-101016. | |
| 1,9-Dimethyluric Acid | 1,9-Dimethyluric Acid is an intermediate in the synthesis of Liberine (L397680), an alkaloid metabolite of Caffeine (C080100), a bitter, white crystalline xanthine alkaloid that acts as a stimulant drug and a reversible acetylcholinesterase inhibitor. Caffeine is found in varying quantities in the seeds, leaves, and fruit of some plants, where it acts as a natural pesticide that paralyzes and kills certain insects feeding on the plants. Group: Biochemicals. Grades: Highly Purified. CAS No. 55441-62-8. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C7H8N4O3, Molecular Weight: 196.16. US Biological Life Sciences. | Worldwide |
| 1-Chloro-3-iodopropane | 1-Chloro-3-iodopropane is used as reagent in the synthesis of several organic compounds including that of (-)-Terengganensine A which is a complex heptacyclic monoterpene indole alkaloid. Also used in the synthesis of A-366 which is a potent inhibitor of histone methyltransferase G9a. Group: Biochemicals. Grades: Highly Purified. CAS No. 6940-76-7. Pack Sizes: 1g, 5g. Molecular Formula: C3H6ClI. US Biological Life Sciences. | Worldwide |
| 1-Ethyl-3-hydroxypiperidine | 1-Ethyl-3-hydroxypiperidine acts as a reagent for the preparation of new compounds of N, N-dimethyl-[3- (1-alkylpiperidy) ]carbamates, as potential cholinesterase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 13444-24-1. Pack Sizes: 1g, 2.5g. Molecular Formula: C7H15NO, Molecular Weight: 129.199999999999. US Biological Life Sciences. | Worldwide |
| 1-Ethynylpyrene | 1-Ethynylpyrene is an aryl acetylenic inhibitor of cytochromes P450 1A1 , 1A2 , and 2B1 with IC 50 s of 0.18, 0.32, and 0.04 μM, respectively [1]. 1-Ethynylpyrene is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 34993-56-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg; 500 mg. Product ID: HY-131452. | |
| 1-Methyl-4-(4-nitrophenyl)piperazine | 1-methyl-4-(4-nitrophenyl)piperazine was a reagent in the preparation of diaminopyrimidines as reversible and irreversible inhibitors of mutant EGFR tyrosine kinases for treatment of non-small-cell lung cancer. It was also used in the prepn. of disubstituted pyrimidine compds. as EGFR or/and ALK inhibitors useful in the treatment of diseases. Group: Biochemicals. Grades: Highly Purified. CAS No. 16155-03-6. Pack Sizes: 500mg, 1g. Molecular Formula: C11H15N3O2, Molecular Weight: 221.26. US Biological Life Sciences. | Worldwide |
| 1-Naphthyl Phosphate Monosodium Salt Monohydrate, 99% | A non-specific phosphatase inhibitor. Inhibits acid, alkaline and protein phosphatases. Group: Biochemicals. Alternative Names: α-Naphthyl phosphate monosodium salt monohydrate;?α-Naphthyl phosphoric acid monosodium salt monohydrate. Grades: Reagent Grade. CAS No. 81012-89-7. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| 1-Naphthyl phosphate potassium salt | 1-Naphthyl phosphate potassium salt is a non-specific phosphatase inhibitor which acts on acid, alkaline, and protein phosphatases. Synonyms: α-Naphthyl acid phosphate monopotassium salt; napthalen-1-yl 3,5-dinitrobenzoate; naphthalen-1-yl dihydrogen phosphate potassium. Grades: ≥95%. CAS No. 100929-85-9. Molecular formula: C10H8O4P·K. Mole weight: 262.24. | |
| 1-Octyne | 1-Octyne was used as a mechanism-based inhibitor of AlkB (nonheme di-iron alkane monooxygenase). Group: Biochemicals. Grades: Highly Purified. CAS No. 629-05-0. Pack Sizes: 25g, 100 g. Molecular Formula: C8H14, Molecular Weight: 110.2. US Biological Life Sciences. | Worldwide |
| 20-Desethyl-20-methyl-10-hydroxy-7-ethylcamptothecin | 20-Desethyl-20-methyl-10-hydroxy-7-ethylcamptothecin is an intermediate in the synthesis of Irinotecan Hydrochloride (I767500), a DNA topoisomerase inhibitor and also a derivative of Camptothecin (C175145), an antitumor alkaloid. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C21H18N2O5. US Biological Life Sciences. | Worldwide |
| 2-(3-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine | 2-(3-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ALK5 INHIBITOR I;2-(3-(6-METHYLPYRIDIN-2-YL)-1H-PYRAZOL-4-YL)-1,5-NAPHTHYRIDINE;TGF-BETA RI KINASE INHIBITOR II;TRANSFORMING GROWTH FACTOR-BETA TYPE I RECEPTOR KINASE INHIBITOR I;2-(3-(6-Methylpyridine-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine;SJN 2511;2-[3-(6-Methyl-2-pyridinyl)-1H-pyrazol-4-yl]-1,5-naphthyridine;RepSox. CAS No. 446859-33-2. Molecular formula: C17H13N5. Mole weight: 287.31862. Purity: 98%+. IUPACName: 2-[5-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl]-1,5-naphthyridine. Canonical SMILES: CC1=CC=CC(=N1)C2=C(C=NN2)C3=NC4=C(C=C3)N=CC=C4. Density: 1.297g/cm³. Product ID: ACM446859332. Alfa Chemistry ISO 9001:2015 Certified. |  |
| 2-(3-Butyn-1-yl)-1,3-dioxolane-2-ethanol | 2-(3-Butyn-1-yl)-1,3-dioxolane-2-ethanol acts as a reagent for the design and synthesis of minimalist terminal alkyne-containing diazirine photo-crosslinkers and their incorporation into kinase inhibitors for cell- and tissue-based proteome profiling. Group: Biochemicals. Grades: Highly Purified. CAS No. 91798-92-4. Pack Sizes: 500mg, 1g. Molecular Formula: C9H14O3, Molecular Weight: 170.21. US Biological Life Sciences. | Worldwide |
| 2-?(4-?Ethyl-?3-?iodophenyl)?-?2-?methylpropanoic Acid | 2-?(4-?Ethyl-?3-?iodophenyl)?-?2-?methylpropanoic Acid is an intermediate of Alectinib (C183360), a highly selective and potent anaplastic lymphoma kinase (ALK) inhibitor capable of blocking the resistant gatekeeper mutant, which results in reduced cell growth. Group: Biochemicals. Grades: Highly Purified. CAS No. 1256584-73-2. Pack Sizes: 10mg, 50mg. Molecular Formula: C12H15IO2, Molecular Weight: 318.149999999999. US Biological Life Sciences. | Worldwide |
| 2-?(4-?Ethylphenyl)?-?2-?methylpropanoic Acid | 2-?(4-?Ethylphenyl)?-?2-?methylpropanoic Acid an intermediate of Alectinib (C183360), a highly selective and potent anaplastic lymphoma kinase (ALK) inhibitor capable of blocking the resistant gatekeeper mutant, which results in reduced cell growth. Group: Biochemicals. Grades: Highly Purified. CAS No. 1247119-83-0. Pack Sizes: 25mg, 50mg. Molecular Formula: C12H16O2, Molecular Weight: 192.25. US Biological Life Sciences. | Worldwide |
| 2-[ (4-nitrophenyl) amino]ethanol | 2-[ (4-nitrophenyl) amino]ethanol is used to prepare phenylpurinediamine derivatives as a class of reversible kinase inhibitors targeting both EGFR-activating and resistance mutations of lung cancer. It is also used to synthesize benzannulated N-heterocycles via palladium-catalyzed domino intermolecular alkylation / intramolecular amination of functionalized aryl iodides and bromoalkylamines. Group: Biochemicals. Grades: Highly Purified. CAS No. 1965-54-4. Pack Sizes: 1g, 5g. Molecular Formula: C8H10N2O3, Molecular Weight: 182.18. US Biological Life Sciences. | Worldwide |
| 2-(4-Pentynyloxy)tetrahydro-2H-pyran | 2-(4-Pentynyloxy)tetrahydro-2H-pyran is used as a reagent in the synthesis of (+)-Citrafungin A, an alkyl citrate compound that acts as a geranyl geranyl transferase (GGTase) inhibitor and also exhibits antifungal activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 62992-46-5. Pack Sizes: 1g, 10g. Molecular Formula: C10H16O2, Molecular Weight: 168.23. US Biological Life Sciences. | Worldwide |
| 2-Amino-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-5-carboxylic Acid tert-Butyl Ester | 2-Amino-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-5-carboxylic Acid tert-Butyl Ester is a reagent used in the synthesis of 2-(thiazol-2-amino)-4-arylaminopyrimidines, which are anaplastic lymphoma kinase (ALK) inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 365996-05-0. Pack Sizes: 250mg, 500mg. Molecular Formula: C11H17N3O2S, Molecular Weight: 255.34. US Biological Life Sciences. | Worldwide |
| 2-Bromo α-Ergocryptine Mesylate | 2-Bromo-α-Ergocryptine is a dopamine receptor agonist. 2-Bromo-α-Ergocryptine is a derivative of the ergotoxin group of ergot alkaloids. 2-Bromo-α-Ergocryptine is a prolactin inhibitor; antiparkinsonian. Group: Biochemicals. Alternative Names: (5α)-2-Bromo-12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)ergotaman-3',6',18-trione Methanesulfonate; 2-Bromoergocryptine; Bagren; Bromocriptine Methanesulfonate; Bromocryptine Mesylate; CB 154; Parlodel; Pravidel. Grades: Highly Purified. CAS No. 22260-51-1. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| 2-Chloro-6-methylpyridin-3-ol | 2-Chloro-6-methylpyridin-3-ol is a reagent in the preparation of 1-amino-4-(3-pyridinyloxy)pyridines as ALK5 (activin like kinase 5) inhibitors and anticancer agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 35680-24-1. Pack Sizes: 1g, 10g. Molecular Formula: C6H6ClNO, Molecular Weight: 143.57. US Biological Life Sciences. | Worldwide |
| 2-Fluoro-4-picoline | 2-Fluoro-4-picoline has been used as a reactant for the preparation of 2-(3-alkoxy-1H-pyrazol-1-yl)azines as inhibitors of human dihydroorotate dehydrogenase (DHODH). Group: Biochemicals. Grades: Highly Purified. CAS No. 461-87-0. Pack Sizes: 1g, 5g. Molecular Formula: C6H6FN, Molecular Weight: 111.12. US Biological Life Sciences. | Worldwide |
| 2-Fluoro-6-hydroxyphenylboronic Acid | 2-Fluoro-6-hydroxyphenylboronic Acid is a synthetic reagent used in the preparation of alkylene-bridged [(3,4-dihydro-2H-benzo[b][1,4]oxazinyl) or (piperidinyl)(biphenyl-3-yl)pyrazolo[1,5-a]pyrimidinyl](tert-butoxy)acetic acid derivatives as HIV integrase inhibitors for treating HIV infection. Group: Biochemicals. Grades: Highly Purified. CAS No. 1256345-60-4. Pack Sizes: 250mg, 1g. Molecular Formula: C6H6BFO3. US Biological Life Sciences. | Worldwide |
| 2-Hydroxy-2- (6'- (hydroxymethyl) -5'-oxo-3', 5', 8', 8a'-tetrahydro-2'H-spiro[[1, 3]dioxolane-2, 1'-indolizin]-7'-yl) -N- ( (S) -1-phenylethyl) propanamide | 2-Hydroxy-2- (6'- (hydroxymethyl) -5'-oxo-3', 5', 8', 8a'-tetrahydro-2'H-spiro[[1, 3]dioxolane-2, 1'-indolizin]-7'-yl) -N- ( (S) -1-phenylethyl) propanamide is an intermediate in the synthesis of Irinotecan Hydrochloride (I767500), a DNA topoisomerase inhibitor and also a derivative of Camptothecin (C175145), an antitumor alkaloid. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 5mg. Molecular Formula: C22H28N2O6. US Biological Life Sciences. | Worldwide |
| (2-Hydroxypropyl)-gamma-cyclodextrin | (2-Hydroxypropyl)-gamma-cyclodextrin is a water-soluble alkylated cyclodextrin derivative. It can help improve the solubility of the drug in oral preparations or preparations. (2-Hydroxypropyl)-gamma-cyclodextrin is used for the dissolution of macromolecules and cell culture applications. (2-Hydroxypropyl)-gamma-cyclodextrin has been used to study its inhibitory effect on complement products and the inflammation induced by cholesterol crystals (CC) in plasma samples. Synonyms: 2-hydroxypropyl Ethers γ-Cyclodextrin; HGC. CAS No. 128446-34-4. Molecular formula: C7H6FNO2. Mole weight: 155.13. | |
| 2-Keto Crizotinib | 2-Keto Crizotinib is an impurity of Crizotinib, a potent and selective dual inhibitor of mesenchymal-epithelial transition factor (c-MET) kinase and anaplastic lymphoma kinase (ALK). Crizotinib is a potential antitumor agent. Synonyms: 4-[4-[6-Amino-5-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-3-pyridinyl]-1H-pyrazol-1-yl]-2-piperidinone. Grades: > 95%. CAS No. 1415558-82-5. Molecular formula: C21H20Cl2FN5O2. Mole weight: 464.32. | |
| 2-Methoxyacetic Acid-d3 | Isotope labelled analogue of 2-Methoxyacetic Acid, a synthetic intermediate in the synthesis of dimethyl (alkyloxy) [ (methylsulfonyl) phenyl]furanones as COX-2 inhibitors. Group: Biochemicals. Alternative Names: 2-Methoxyacetic Acid-d3; Methoxyacetic Acid-d3; Methoxyethanoic Acid-d3; NSC 7300-d3; Methoxyacetic Acid-d3. Grades: Highly Purified. CAS No. 345910-00-1. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 2-?Methyl-?2-? (4-?vinylphenyl) ?propanoic Acid | 2-?Methyl-?2-? (4-?vinylphenyl) ?propanoic Acid is an intermediate of Alectinib (C183360), a highly selective and potent anaplastic lymphoma kinase (ALK) inhibitor capable of blocking the resistant gatekeeper mutant, which results in reduced cell growth. Group: Biochemicals. Grades: Highly Purified. CAS No. 1256584-72-1. Pack Sizes: 1mg, 5mg. Molecular Formula: C12H14O2, Molecular Weight: 190.24. US Biological Life Sciences. | Worldwide |
| 2-Phenylethylamine HCl | 2-Phenylethylamine is a natural alkaloid. It functions as a neuromodulator and a neurotransmitter in the central nervous system. It is found in several different strains of fungi and bacteria, such as Lactobacillus and Pseudomonas. 2-Phenylethylamine also possesses anti-microbial effects against strains of E. Coli. 2-Phenylethylamine is a substrate of B monoamine oxidase, and derivatives of 2-Phenylethylamine are metabolites in other parts of the central nervous system. Increased levels of 2-Phenylethylamine are found following aerobic exercise. 2-Phenylethylamine is studied to determine the various roles it plays in the central nervous system and other tissues. As a reagent, it has been used in the construction of anti-depressants, inhibitors of leukotrienes and adenosine derivatives. Group: Biochemicals. Alternative Names: Phenethylammonium chloride; Beta-Phenylethylamine hydrochloride; β-Phenylethylamine hydrochloride. Grades: Highly Purified. CAS No. 156-28-5. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C?H??N HCl, Molecular Weight: 121.18. US Biological Life Sciences. | Worldwide |
| 3-((1R,3R)-3-Aminocyclopentyl)-2-(1H-imidazol-5-yl)propanoic Acid | 3-((1R,3R)-3-Aminocyclopentyl)-2-(1H-imidazol-5-yl)propanoic Acid is an intermediate used in the synthesis of imidazolyl-substituted alkanoic acids and related five-membered nitrogen-aromatic derivatives as carboxypeptidase U inhibitors useful as anticoagulants. Group: Biochemicals. Grades: Highly Purified. CAS No. 497158-76-6. Pack Sizes: 10mg, 50mg. Molecular Formula: C11H17N3O2, Molecular Weight: 223.27. US Biological Life Sciences. | Worldwide |
| 3-((1S,3S)-3-Aminocyclopentyl)-2-(1H-imidazol-5-yl)propanoic Acid | 3-((1S,3S)-3-Aminocyclopentyl)-2-(1H-imidazol-5-yl)propanoic Acid is an intermediate used in the synthesis of imidazolyl-substituted alkanoic acids and related five-membered nitrogen-aromatic derivatives as carboxypeptidase U inhibitors useful as anticoagulants. Group: Biochemicals. Grades: Highly Purified. CAS No. 497158-75-5. Pack Sizes: 10mg, 50mg. Molecular Formula: C11H17N3O2, Molecular Weight: 223.27. US Biological Life Sciences. | Worldwide |
| 3-(4-Hydroxyphenyl)-1-propanol | 3-(4-Hydroxyphenyl)-1-propanol is a reagent in the synthesis of heteroaryl methoxyphenyl alkoxyiminoalkyl carboxyl ic acids as leukotriene biosynthesis inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 10210-17-0. Pack Sizes: 1g, 2.5g. Molecular Formula: C9H12O2. US Biological Life Sciences. | Worldwide |
| 3,5-Dimethyl-1H-pyrrole-2-carboxaldehyde | Intermediate used in the synthesis of a series of anaplastic lymphoma kinase (ALK) inhibitors, a new target for therapy of non-small-cell lung cancer (NSCLC). Group: Biochemicals. Alternative Names: 2,4-Dimethyl-5-formylpyrrole; 2,4-Dimethylpyrrole-5-carboxaldehyde; 2-Formyl-3,5-dimethylpyrrole. Grades: Highly Purified. CAS No. 2199-58-8. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| 3-Bromopropionitrile | 3-Bromopropionitrile acts as a reagent in the preparation of bisindole maleimide derivative useful as α-glucosidase inhibitors for the treatment of diabetesis. Also used in the study of the structure activity relations between alkyl nucleophilic chemicals causing duodenal ulcer and adrenocortical necrosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 2417-90-5. Pack Sizes: 10g, 25g. Molecular Formula: C3H4BrN, Molecular Weight: 133.97. US Biological Life Sciences. | Worldwide |
| 3-Butyn-1-amine | 3-Butyn-1-amine is a reagent used to prepare alkylaminodiaryl -dihydropyrazoles as potent, water-soluble inhibitors of mitotic kinesin spindle protein inhibitors. It is also used to synthesize oxoquinoline derivatives as cannabinoid CB2 receptor ligands. Group: Biochemicals. Grades: Highly Purified. CAS No. 14044-63-4. Pack Sizes: 100mg, 1 g. Molecular Formula: C4H7N, Molecular Weight: 69.11. US Biological Life Sciences. | Worldwide |
| 3-Butynoic acid | 3-Butynoic acid is an inhibitor of acyl CoA dehydrogenase [1]. 3-Butynoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Natural products. CAS No. 2345-51-9. Pack Sizes: 10 mM * 1 mL; 250 mg; 500 mg; 1 g. Product ID: HY-W004784. | |
| 3-Chloro-4- (2-pyridylmethyloxy) nitrobenzene | 3-Chloro-4- (2-pyridylmethyloxy) nitrobenzene was used to synthesize aniline 'headgroups' and incorporat them into an alkynyl thienopyrimidine series of EGFR and ErbB-?2 inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 179687-79-7. Pack Sizes: 1g, 5g. Molecular Formula: C12H9ClN2O3, Molecular Weight: 264.66. US Biological Life Sciences. | Worldwide |
| 3'-demethylstaurosporine O-methyltransferase | Catalyses the final step in the biosynthesis of staurosporine, an alkaloidal antibiotic that is a potent inhibitor of protein kinases, especially protein kinase C. Group: Enzymes. Synonyms: 3'-demethoxy-3'-hydroxystaurosporine O-methyltransferase; staurosporine synthase. Enzyme Commission Number: EC 2.1.1.139. CAS No. 212906-74-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1734; 3'-demethylstaurosporine O-methyltransferase; EC 2.1.1.139; 212906-74-6; 3'-demethoxy-3'-hydroxystaurosporine O-methyltransferase; staurosporine synthase. Cat No: EXWM-1734. |  |
| 3-Hydroxy-3-methylglutaric-d3 Anhydride | A 3-Alkyl-3-hydroxyglutaric acid; a new class of hypocholesterolemic HMG CoA reductase inhibitors. Group: Biochemicals. Alternative Names: 3-Hydroxy-3-methylpentane-1,5-dioic-d3 Anhydride; Dihydro-4-hydroxy-4-methyl-. Grades: Highly Purified. CAS No. 115135-38-1. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 4,5-Dimethoxycanthin-6-one | 4,5-Dimethoxycanthin-6-one is a potent and uncompetitive inhibitor of CYP1A2 -mediated phenacetin O-deethylation with an IC 50 value of 1.7μM and a K i value of 2.6 μM. 4,5-Dimethoxycanthin-6-one, as an alkaloid, is isolated from the wood of Picrasma quassioides BENNET (Simaroubaceae) [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 18110-87-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-N1882. | |
| 4-Methylcatechol | 4-Methylcatechol is an intermediate in the degradation of some alkylbenzenes and an orally active suicide inhibitor of catechol 2,3-dioxygenase ( C23O ). 4-Methylcatechol induces apoptosis in melanoma cells through oxidative stress, but some studies have also shown that 4-Methylcatechol is carcinogenic. In addition, 4-Methylcatechol has antiplatelet and blood pressure-lowering activities. 4-Methylcatechol can also inhibit protein oxidation in beef but does not disulfide formation [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Natural products. CAS No. 452-86-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-W012814. | |
| 4-Methylsalicylic acid | 4-Methylsalicylic acid is a salicylic acid. 4-Methylsalicylic acid derivative is a selective tissue-nonspecific alkaline phosphatase ( TNAP ) and intestinal alkaline phosphatase ( IAP ) inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 50-85-1. Pack Sizes: 10 mM * 1 mL; 25 g; 50 g. Product ID: HY-78144. | |
| 4-Methylsalicylic Acid | 4-Methylsalicylic acid is a salicylic acid. 4-Methylsalicylic acid derivative is a selective tissue-nonspecific alkaline phosphatase (TNAP) and intestinal alkaline phosphatase (IAP) inhibitor. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-Hydroxy-4-Methylbenzoic Acid. Product Category: Inhibitors. Appearance: Powder. CAS No. 50-85-1. Molecular formula: C8H8O3. Mole weight: 152.15. Purity: 0.99. IUPACName: 2-hydroxy-4-methylbenzoic acid. Canonical SMILES: CC1=CC(=C(C=C1)C(=O)O)O. Density: 1.304 g/cm³. Product ID: ACM50851. Alfa Chemistry ISO 9001:2015 Certified. | |
| 5-Br-dU-CPG | 5-Br-dU-CPG, a chemical highly relevant to the biomedicine industry, offers paradigm-shifting possibilities with regards to the development of nucleic acid derivatives utilized in the treatment of cancer, viral infections, and genetic disorders. As a potent inhibitor for nucleic acid synthesis, 5-Br-dU-CPG paves the way for an epochal suppression of tumor cell proliferation. Evidencing its versatility, this chemical also displays antiviral activity against herpes simplex virus-1, emphasizing its potential in treating viral infections as well. Synonyms: 5'-Dimethoxytrityl-5-bromo-2'-deoxyUridine, 2'-succinoyl-long chain alkylamino-CPG. | |
| 5-Bromo-6-chloro-3-indolyl phosphate disodium salt monohydrate | 5-Bromo-6-chloro-3-indolyl phosphate disodium salt monohydrate is a crucial recompound within the biomedical sector, serving as an indispensable tool for conducting enzymatic assays. Its utilization facilitates the exploration of diverse cellular mechanisms by enabling the detection of alkaline phosphatase. This compound assumes particular significance in the realm of drug exploration and development as it greatly facilitates the identification and screening of potential enzyme inhibitors. Synonyms: Magenta phosphate sodium salt. CAS No. 404366-59-2. Molecular formula: C8H4BrClNO4PNa2.H2O. Mole weight: 388.45. | |
| 5-Chloro-2-nitroanisole | 5-Chloro-2-nitroanisole is involved in the synthesis of orally bioavailable anaplastic lymphoma kinases (ALK) inhibitors as anticancer drugs. In addition it is used in the synthesis of kinesin spindle protein (KSP) inhibitors which are responsible for the spindle pole separation which occurs during mitosis in cancer cells. Group: Biochemicals. Alternative Names: 4-Chloro-2-methoxy-1-nitrobenzene; 5-Chloro-2-nitroanisole; 1-Chloro-3-methoxy-4-nitrobenzene; 2-Methoxy-4-chloronitrobenzene; 2-Nitro-5-chloroanisole; 3-Methoxy-4-nitro-1-chlorobenzene; 4-Chloro-2-(methyloxy)-1-nitrobenzene; 4-Chloro-2-methoxy-1-nitrobenzene; 4-Chloro-2-methoxynitrobenzene; 5-Chloro-2-nitroanisole; 5-Chloro-2-nitrophenyl Methyl Ether; NSC 60112. Grades: Highly Purified. CAS No. 6627-53-8. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |
| 6-Bromo[1, 2, 4]triazolo[1, 5-a]pyridine | A selective inhibitor of ALK5 kinase. Group: Biochemicals. Grades: Highly Purified. CAS No. 356560-80-0. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| 6-(Dimethylamino)-1-hexanol | An alkanolamine as lysosomotropic agent and choline uptake inhibitor. Group: Biochemicals. Alternative Names: (6-Hydroxyhexyl) dimethylamine; 6- (Dimethylamino) hexanol; KL 25; Kao 25; Kaolizer 25; NSC 165607. Grades: Highly Purified. CAS No. 1862-07-3. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| 8-Oxo-Benzylguanine | 8-Oxo-Benzylguanine is a derivative of O-Benzylguanine, an reversible inhibitor of the mammalian DNA repair protein, O6-alkylguanine-DNA alkyltransferase. O-Benzylguanine is known to assists in the protection against carcinogenic and therapeutic alkylating agents. Group: Biochemicals. Alternative Names: 2-Amino-7,9-dihydro-6-(phenylmethoxy)-8H-purin-8-one; NU 6043. Grades: Highly Purified. CAS No. 158754-46-2. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| 8-Oxo-Benzylguanine | As a derivative of O-Benzylguanine, 8-Oxo-Benzylguanine is a reversible inhibitor of the mammalian DNA repair protein, O6-alkylguanine-DNA alkyltransferase and O-Benzylguanine is known to assist in the protection against carcinogenic and therapeutic alkylating agents. Synonyms: 2-Amino-7,9-dihydro-6-(phenylmethoxy)-8H-purin-8-one; NU 6043. CAS No. 158754-46-2. Molecular formula: C12H11N5O2. Mole weight: 257.25. | |
| A-77-01 | A-77-01 is an inhibitor of TGF-β type I receptor superfamily activin-like kinase ALK5( IC50 =25nM). Uses: Potent alk5 inhibitor. Synonyms: A77-01; A 77-01; A-77-01. 4-[3-(6-Methyl-2-pyridinyl)-1H-pyrazol-4-yl]-quinoline;4-[3-(6-Methyl-pyridin-2-yl)-1H-pyrazol-4-yl]-quinoline. Grades: ≥98%. CAS No. 607737-87-1. Molecular formula: C18H14N4. Mole weight: 286.34. | |
| A 83-01 | A 83-01 is a potent inhibitor of TGF-β type I receptor ALK5 kinase , type I nodal receptor ALK4 and type I nodal receptor ALK7 , with IC 50 s of 12 nM, 45 nM and 7.5 nM against the transcription induced by ALK5 , ALK4 and ALK7 , respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 909910-43-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10432. | |
| A-83-01 | A 83-01 is an inhibitor of TGF-β type I receptor kinase (ALK5), activin type IB receptor (ALK4), and nodal type I receptor (ALK7) (IC50s = 12, 45, and 7.5 nM, respectively). It blocks the phosphorylation of SMAD2/3 and inhibits TGF-β-induced epithelial-to-mesenchymal transition. Synonyms: A8301; A 8301; A-8301. Grades: 98%. CAS No. 909910-43-6. Molecular formula: C25H19N5S. Mole weight: 421.52. | |
| A 83-01 (3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide) | A selective inhibitor of TGF-beta type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7 (IC50 values are 12, 45 and 7.5nM respectively). Blocks. Group: Biochemicals. Alternative Names: 3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide. Grades: Highly Purified. CAS No. 909910-43-6. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
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