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Catalyst used for rearrangement of allylic acetates. Catalyst used for alkane carbon-hydrogen bond functionalization. Catalyst used for room temperature hydroamination of N-alkenyl ureas. Catalyst used for hydration of alkynes. Group: Gold series of catalysts. Alternative Names: 852445-83-1; SC10711; 1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene gold(I)chloride; {1,3-Bis[2,6-di(propan-2-yl)phenyl]-1,3-dihydro-2H-imidazol-2-ylidene}(chloro)gold; AKOS015951030; 1,3-Bis(2,6-diisopropylphenyl-imidazol-2-ylidene)gold(I) chloride; (1,3-Bis(2,6-diisopropylphenyl)-1,3-dihydro-2H-imidazol-2-ylidene)(chloro)gold. CAS No. 852445-83-1. Molecular formula: C27H36AuClN2. Mole weight: 621.016g/mol. IUPACName: [1,3-bis[2,6-di(propan-2-yl)phenyl]imidazol-2-ylidene]-chlorogold. Canonical SMILES: CC (C)C1=C (C (=CC=C1)C (C)C)N2C=CN (C2=[Au]Cl)C3=C (C=CC=C3C (C)C)C (C)C. Catalog: ACM852445831.
1S,2S-DHAC-Phenyl Trost Ligand
The palladium complexes of the Trost ligands are effective in a variety of allylic substitution reactions involving carbon, nitrogen, oxygen, sulfur, and fluorides nucleophiles. Group: Other nitrogen-donor ligands. Alternative Names: N, N'- ( (1S, 2S)-cyclohexane-1, 2-diyl)bis (2- (diphenylphosphino)benzamide); ROST LIGAND; (1S, 2S)-(-)-1, 2-DIAMINOCYCLOHEXANE-N, N'-BIS(2'-DIPHENYLPHOSPHINOBENZOYL); SC11303; (S,S)-DACH-phenyl Trost ligand, 95%; 169689-05-8; (1S,2S)-(-)-1,2-Diaminocyclohexane-N,N inverted exclamation marka-bis(2-diphenylphosphinobenzoyl); (1S,2S)-(-)-1,2-DIAMINOCYCLOHEXANE-N,N'-BIS(2-DIPHENYLPHOSPHINOBENZOYL); N, N'- ( (1S, 2S)-cyclohexane-1, 2-diyl)bis (2- (diphenylphosphanyl)benzamide); ZINC169731035. CAS No. 169689-05-8. Molecular formula: C44H40N2O2P2. Mole weight: 690.764g/mol. IUPACName: 2-diphenylphosphanyl-N-[ (1S, 2S) -2-[ (2-diphenylphosphanylbenzoyl) amino]cyclohexyl]benzamide. Canonical SMILES: C1CCC (C (C1)NC (=O)C2=CC=CC=C2P (C3=CC=CC=C3)C4=CC=CC=C4)NC (=O)C5=CC=CC=C5P (C6=CC=CC=C6)C7=CC=CC=C7. Catalog: ACM169689058.
Atorvastatin derivative. Group: Biochemicals. Alternative Names: 2-(4-Fluorophenyl)- β , δ -dihydroxy-5- (1-methylethyl)-3-phenyl-4-[ (phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid 2-Propenyl Ester; ( βR,δR)-2-(4-Fluorophenyl)- β , δ -dihydroxy-5- (1-methylethyl)-3-phenyl-4-[ (phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid 2-Propen-1-yl Ester. Grades: Highly Purified. CAS No. 915092-85-2. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
Atorvastatin Lactam Allyl Ester
Intermediate in the preparation of Atorvastatin degradation products. Group: Biochemicals. Alternative Names: ( βR,δR)-5-(4-Fluorophenyl)-2,3-dihydro- β , δ -dihydroxy-3- (1-methylethyl)-2-oxo-4-phenyl-3-[ (phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid Allyl Ester. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Boc-3,4-dichloro-D-phenylalanine
Boc-3,4-dichloro-D-phenylalanine is used to prepare fluorinated β-aminoacyl 1,2,4-triazolo[4,3-a]piperazine amides as dipeptidyl peptidase IV inhibitors and antidiabetic agents. It is also used in the synthesis of N-[(R,R)-(E)-1-(3,4-dichlorobenzyl)-3-(2-oxoazepan-3-yl)carbamoyl]allyl-N-methyl-3,5-bis(trifluoromethyl)benzamide as a potent and orally active dual neurokinin NK1/NK2 receptor antagonist. Synonyms: Boc-D-Phe(3,4-DiCl)-OH; Boc-D-Phe(3,4-Cl2)-OH; (R)-Boc-2-amino-3-(3,4-dichlorophenyl)propionic acid; Boc-D-Phe(3,4-Cl2)-OH; (R)-2-((tert-Butoxycarbonyl)amino)-3-(3,4-dichlorophenyl)propanoic acid; D-Phenylalanine, 3,4-dichloro-N-[(1,1-dimethylethoxy)carbonyl]-; Boc-D-3,4-Dichlorophenylalanine; AK162594; N-BOC-3,4-DICHLORO-D-PHENYLALANINE. Grades: ≥ 98% (HPLC). CAS No. 114873-13-1. Molecular formula: C14H17Cl2NO4. Mole weight: 334.20.
CFTR Activator, Cact-A1
A cell-permeable, non-toxic aminopyrazolocarbonitr i le compound that acts as a potent, selective, reversible and cAMP-independent activator of CFTR-dependent Cl- channel in airway epithelial cells (EC50 = 1.6uM in CFTR-expressing Fisher rat thyroid cells). Also shown to activate deltaF508-CFTR in primary CF-HBE cell cultures (EC50 = 3.5uM). Reported to directly bind to the same site as CFTRinh-172. Does neither elevate intracellular cAMP levels nor appear to have any requirement for cAMP agonist, such as forskolin. Shown to additively potentiate the G551D-CFTR Cl- current activated by forskolin with CFTR potentiator, VX-770. Exerts no effect on either Ca2+-activated Cl- channel (TMEM16A) or intracellular Ca2+ levels. Group: Biochemicals. Alternative Names: Cystic Fibrosis Transmembrane Conductance Regulator Activator, Cact-A1, 5-((Z)-2-(2-(Allyloxy)phenyl)-1-cyanovinyl)-3-amino-1H-pyrazole-4-carbonitrile, (Z)-3-(2-(2-(Allyloxy)phenyl)-1-cyanovinyl)-5-amino-1H-pyrazole-4-carbonitrile. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??N?O. US Biological Life Sciences.
A useful building block in the synthesis of various pharmaceuticals. Synonyms: Z-D-Asp(OAll)-OH; N-[(Phenylmethoxy)carbonyl]-D-aspartic Acid 4-(2-Propen-1-yl) Ester. Grades: ≥ 98% (HPLC). CAS No. 1272755-66-4. Molecular formula: C15H17NO6. Mole weight: 307.20.