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The enzyme participates in the nicotine degradation pathway of the soil bacterium Arthrobacter nicotinovorans. Has a very weak monoamineoxidase (EC 1.4.3.4) activity with 4-aminobutanoate. Group: Enzymes. Synonyms: mao (gene name, ambiguous). Enzyme Commission Number: EC 1.5.3.21. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1549; 4-methylaminobutanoate oxidase (methylamine-forming); EC 1.5.3.21; mao (gene name, ambiguous). Cat No: EXWM-1549.
cyclohexylamineoxidase
A flavoprotein (FAD). Some other cyclic amines can act instead of cyclohexylamine, but not simple aliphatic and aromatic amides. Group: Enzymes. Enzyme Commission Number: EC 1.4.3.12. CAS No. 63116-97-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1468; cyclohexylamineoxidase; EC 1.4.3.12; 63116-97-2. Cat No: EXWM-1468.
diamineoxidase
A group of enzymes that oxidize diamines, such as histamine, and also some primary monoamines but have little or no activity towards secondary and tertiary amines. They are copper quinoproteins (2,4,5-trihydroxyphenylalanine quinone) and, like EC 1.4.3.21 (primary-amineoxidase) but unlike EC 1.4.3.4 (monoamineoxidase), they are sensitive to inhibition by carbonyl-group reagents, such as semicarbazide. Group: Enzymes. Synonyms: amineoxidase (ambiguous); amineoxidase (copper-containing) (ambiguous); CAO (ambiguous); Cu-containing amineoxidase (ambiguous); copper amineoxidase (ambiguous); diamineoxidase (ambiguous); diamino oxhydrase (ambiguous); histaminase; histamine deaminase (incorrect); semicarbazide-sensitive amineoxidase (incorrect); SSAO (incorrect). Enzyme Commission Number: EC 1.4.3.22. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1477; diamineoxidase; EC 1.4.3.22; amineoxidase (ambiguous); amineoxidase (copper-containing) (ambiguous); CAO (ambiguous); Cu-containing amineoxidase (ambiguous); copper amineoxidase (ambiguous); diamineoxidase (ambiguous); diamino oxhydrase (ambiguous); histaminase; histamine deaminase (incorrect); semicarbazide-sensitive amineoxidase (incorrect); SSAO (incorrect). Cat No: EXWM-1477.
DiamineOxidase from porcine kidney
Synonyms: Amine:oxygen oxidoreductase (deaminating) (pyridoxal-containing). CAS No. 9001-53-0.
monoamineoxidase
A mitochondrial outer-membrane flavoprotein (FAD) that catalyses the oxidative deamination of neurotransmitters and biogenic amines. Acts on primary amines, and also on some secondary and tertiary amines. It differs from EC 1.4.3.21, primary-amineoxidase as it can oxidize secondary and tertiary amines but not methylamine. This enzyme is inhibited byacetylenic compounds such as chlorgyline, 1-deprenyl and pargyline but, unlike EC 1.4.3.21 and EC 1.4.3.22 (diamineoxidase), it is not inhibited by semicarbazide. Group: Enzymes. Synonyms: adrenalin oxidase; adrenaline oxidase; amineoxidase (ambiguous); amineoxidase (flavin-containing); amine:oxygen ox. Enzyme Commission Number: EC 1.4.3.4. CAS No. 9001-66-5. MonoamineOxidase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1481; monoamineoxidase; EC 1.4.3.4; 9001-66-5; adrenalin oxidase; adrenaline oxidase; amineoxidase (ambiguous); amineoxidase (flavin-containing); amine:oxygen oxidoreductase (deaminating) (flavin-containing); epinephrine oxidase; MAO; MAO A; MAO B; MAO-A; MAO-B; monoamineoxidase A; monoamineoxidase B; monoamine:O2 oxidoreductase (deaminating); polyamineoxidase (ambiguous); serotonin deaminase; spermidine oxidase (ambiguous); spermine oxidase (ambiguous); tyraminase; tyramineoxidase. Cat No: EXWM-1481.
MonoamineOxidase A from Human, Recombinant
MAO's are proteins of the mitochondrial membrane. These enzymes are responsible for catalyzing oxidative deamination of endo-and xenobiotic amines. Substrate specificity differs for each isozyme. Monoamineoxidase a contains binding sites for 8α-s-cysteinyl-fad. Applications: Monoamineoxidase a has been used in a study to assess abnormal behavior in a large kindred of males where a deficiency of enzymatic activity of monamineoxidase a was found. it has also been used in a study to investigate an ass ociation between smoking and the inhibition of maoa. Group: Enzymes. Synonyms: MAO-A; MAOA; EC 1.4.3.4; MonoamineOxidase A; adrenalin oxidase; adrenaline oxidase; amineoxidase (ambiguous); amineoxidase (flavin-containing); amine:oxygen oxidoreducta. Enzyme Commission Number: EC 1.4.3.4. CAS No. 231-791-2. MonoamineOxidase. Storage: -70°C. Source: Baculovirus infected BTI insect cells. Species: Human. MAO-A; MAOA; EC 1.4.3.4; MonoamineOxidase A; adrenalin oxidase; adrenaline oxidase; amineoxidase (ambiguous); amineoxidase (flavin-containing); amine:oxygen oxidoreductase (deaminating) (flavin-containing); epinephrine oxidase; monoamine:O2 oxidoreductase (deaminating); polyamineoxidase (ambiguous); serotonin deaminase; spermidine oxidase (ambiguous); spermine oxidase (ambiguous); tyraminase; tyramineoxidase. Cat No: NATE-0440.
MonoamineOxidase B from Human, Recombinant
MAO's are proteins of the mitochondrial membrane. These enzymes are responsible for catalyzing oxidative deamination of endo-and xenobiotic amines. Substrate specificity differs for each isozyme. Monoamineoxidase b is a mit ochondrial outermembrane flavoenzyme that is a target for antidepressant and neuroprotective drugs. Applications: Drugs that inhibit monoamineoxidase b activity are used for the treatment of various neurological disorders including depression. monoamineoxidase b has been used in a study to assess the effect of age in 23 different regions of the human brain. it has also been used in a study to determine the specific l ocations of monoamineoxidase in the human brain. Group: Enzymes. Synonyms: MAO-B; MAOB; EC 1.4.3.4; Monoamine Oxida. Enzyme Commission Number: EC 1.4.3.4. CAS No. 231-791-2. MonoamineOxidase. Storage: -70°C. Source: Baculovirus infected BTI insect cells. Species: Human. MAO-B; MAOB; EC 1.4.3.4; MonoamineOxidase B; adrenalin oxidase; adrenaline oxidase; amineoxidase (ambiguous); amineoxidase (flavin-containing); amine:oxygen oxidoreductase (deaminating) (flavin-containing); epinephrine oxidase; monoamine:O2 oxidoreductase (deaminating); polyamineoxidase (ambiguous); serotonin deaminase; spermidine oxidase (ambiguous); spermine oxidase (ambiguous); tyraminase; tyramineoxidase. Cat No: NATE-0441.
MonoamineOxidase (Crude Enzyme)
L-Monoamineoxidases (MAO) are a family of enzymes that catalyze the oxidation of monoamines. They are found bound to the outer membrane of mitochondria in most cell types in the body. The enzyme was originally discovered by Mary Bernheim in the liver and was named tyramineoxidase. They belong to the protein family of flavin-containing amine oxidoreductases. This product with the indicated enzyme activity was briefly purified from engineered E. coli. Applications: Synthesis; drug development; analysis; medicine. Group: Enzymes. Synonyms: equilase; caperase; optidase; catalase-peroxidase; CAT. Enzyme Commission Number: EC 1.4.3.4. CAS No. 9001-66-5. MonoamineOxidase. Activity: Undetermined. Appearance: Clear to translucent yellow solution. Storage: at -20 °C or lower, for at least 1 month. Source: E. coli. equilase; caperase; optidase; catalase-peroxidase; CAT. Pack: 100ml. Cat No: NATE-1808.
Monoamineoxidase, plasma
Monoamineoxidase (EC 1.4.3.4) is an enzyme composed of different polypeptides. Monoamine oxidation catalyzes the oxidative deamination of various biological amines in brain and peripheral tissues by producing hydrogen peroxide. Monoamineoxidase plays an important role in maintaining the regulation of synaptic transmission, emotional behavior and other brain functions [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 9001-66-5. Pack Sizes: 100 U. Product ID: HY-E70074.
N1-acetylpolyamineoxidase
The enzyme also catalyses the reaction: N1,N12-diacetylspermine + O2 + H2O = N1-acetylspermidine + 3-acetamamidopropanal + H2O2. No or very weak activity with spermine, or spermidine in absence of aldehydes. In presence of aldehydes the enzyme catalyses the reactions: 1. spermine + O2 + H2O = spermidine + 3-aminopropanal + H2O2, and with weak efficiency 2. spermidine + O2 + H2O = putrescine + 3-aminopropanal + H2O2. A flavoprotein (FAD). This enzyme, encoded by the PAOX gene, is found in mammalian peroxisomes and oxidizes N1-acetylated polyamines at the exo (three-carbon) side of the secondary amine, forming 3-acetamamidopropanal. Since the products of the reactions are deacetylated polyamines, this process is known as polyamine back-conversion. Differs in specificity from EC 1.5.3.14 [polyamineoxidase (propane-1,3-diamine-forming)], EC 1.5.3.15 [N8-acetylspermidine oxidase (propane-1,3-diamine-forming)], EC 1.5.3.16 (spermine oxidase) and EC 1.5.3.17 (non-specific polyamineoxidase). Group: Enzymes. Synonyms: hPAO-1; PAO (ambiguous); mPAO; hPAO; po. Enzyme Commission Number: EC 1.5.3.13. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1540; N1-acetylpolyamineoxidase; EC 1.5.3.13; hPAO-1; PAO (ambiguous); mPAO; hPAO; polyamineoxidase (ambiguous). Cat No: EXWM-1540.
Native Arthrobacter sp. TyramineOxidase
Amineoxidases (AO) are enzymes that catalyze the oxidation of a wide range of biogenic amines including many neurotransmitters, histamine and xenobiotic amines. There are two classes of amineoxidases: flavin-containing (EC 1.4.3.4) and copper-containing (EC 1.4.3.6). Copper-containing AO act as a disulphide-linked homodimer. They catalyse the oxidation of primary amines to aldehydes, with the subsequent release of ammonia and hydrogen peroxide, which requires one copper ion per subunit and topaquinone as cofactor: RCH2NH2 + H2O + O2 <-> RCHO + NH3 + H2O2. The 3 substrates of this enzyme are primary amines (RCH2NH2), H2O, and O2, whereas its 3 products are RCHO, NH3, and H2O2. Native tyramineoxidase (ec 1.4.3.4) was purified from arthrobacter sp. Applications: Useful for enzymatic determiantion of leucine aminopeptidase. Group: Enzymes. Synonyms: TyramineOxidase; TOD; EC 1.4.3.6. Enzyme Commission Number: EC 1.4.3.6. CAS No. 9001-53-0. TyramineOxidase. Activity: > 3 U/mg. Appearance: White to light brown powder. Storage: Store in tightly closed containers, desiccated, protected from light, at-20°C. Form: Freeze dried powder. Source: Arthrobacter sp. TyramineOxidase; TOD; EC 1.4.3.6. Cat No: DIA-158.
Native Bovine Plasma AmineOxidase
Amineoxidase (also known as histaminase) is an enzyme involved in the metabolism, oxidation, and inactivation of histamine within the digestive tract. Bovine plasma amineoxidase has a molecular weight of 170 kDa and an optimum pH of 6.2 for spermine and 7.2 for spermidine. Amineoxidases are divided into two classes:the pyridoxal and copper containing enzyme to which plasma amineoxidase belongs, and the FAD-containing amino oxidases. Natural substrates include catecholamines, tryptamine derivatives and other physiologically active amines. Plasma amineoxidase is used in research requiring nitrogen group transfers. The molecule is composed of two identical polypeptide chai...mM respectively). It was from bovine plasma. chromatographically purified through step five of the procedure of yamada, y., and yasunobu, k., jbc, 237, 1511 (1962). a lyophilized powder. (one iu = 4,330 tabor units). Group: Enzymes. Synonyms: Amineoxidase; EC 1.4.3.21; histaminase; Plasma AmineOxidase. Enzyme Commission Number: EC 1.4.3.21. Purity: Chromatographically purified. AmineOxidase. Mole weight: 170 kDa. Activity: > 17 Tabor units/mg dw. Stability: Stable for 12 months at-20°C. Store at -20°C. Storage: Store at -20°C. Form: lyophilized powder. Source: Bovine Plasma. Species: Bovine. Amineoxidase; EC 1.4.3.21; histaminase; Plasma AmineOxidase. Cat No: NATE-0069.
Native Plant origin DiamineOxidase
DAO is an enzyme (EC 1.4.3.22) composed of 642 amino acids. It is a homo-dimer of two identical subunits. Each subunit contains 2 disulfide bounds and a free cysteine with a theoretical molecular weight of 72,878 daltons per unit (a nominal molecular weight of 73 ±3 kDa is used for analytical purposes). DAO active site contains copper (II) and phenylalanine quinone: 2,4,5-trihydroxyphenylalanine quinone (TPQ). The products of the CuAO-catalysed oxidative deamination of amines such as histamine are various aldehydes, ammonia, and hydrogen peroxide. The copper is essential for activity and is believed to play a redox role in substrate turnover.Plant DAOs (histaminase) differs...oms, various plants, and animals. A review article by R. Medda, et al. in 1995 describes in detail research in this area. Applications: Dao catalyzes the oxidation of diamines (and some monoamines) to produce the aldehyde, ammonia, and h2o2. Group: Enzymes. Synonyms: EC 1.4.3.6; 9001-53-0; Amine:oxygen oxidoreductase (deaminating) (pyridoxal-containing); DiamineOxidase; Amineoxidase (copper-containing). Enzyme Commission Number: EC 1.4.3.6. CAS No. 9001-53-0. DiamineOxidase. Form: Tan Liquid. Source: Pisum sativum. EC 1.4.3.6; 9001-53-0; Amine:oxygen oxidoreductase (deaminating) (pyridoxal-containing); DiamineOxidase; Amineoxidase (copper-containing). Cat No: NATE-0188.
Native Porcine DiamineOxidase
Diamineoxidase from porcine kidney is a homodimer consisting of 2 equal subunits with a molecular weight of 87 kDa each. Each subunit contains one molecule of pyridoxal phosphate and one atom of copper. The molecular mass of the enzyme is found to be 170 kDa. The enzyme is a glycoprotein containing 5% hexose, 3.3% glucosamine, 2.6% N-acetylglucosamine, and 0.25% N-acetylneuraminic acid. The enzyme exhibits a high affinity for concanavalin A. It catalyzes the oxidation of monoamines, diamines, and histamine to aldehydes, ammonia, and hydrogen peroxide. Optimum pH with cadverine and histamine as substrates is found to be 6.3-7.4.2 The enzyme is classified as a copper amine oxid...a luminescence-based test for determining ornithine decarboxylase activity. diamineoxidase from porcine kidney has also been used in a study to investigate n-linked oligosaccharide structures in diamineoxidase. Group: Enzymes. Synonyms: EC 1.4.3.6; 9001-53-0; Amine:oxygen oxidoreductase (deaminating) (pyridoxal-containing); DiamineOxidase; Amineoxidase (copper-containing). Enzyme Commission Number: EC 1.4.3.6. CAS No. 9001-53-0. DiamineOxidase. Activity: > 0.05 unit/mg solid. Storage: -20°C. Source: Porcine kidney. Species: Porcine. EC 1.4.3.6; 9001-53-0; Amine:oxygen oxidoreductase (deaminating) (pyridoxal-containing); DiamineOxidase; Amineoxidase (copper-containing).
paromamine 6'-oxidase
Contains FAD. Involved in the biosynthetic pathways of several clinically important aminocyclitol antibiotics, including kanamycin, butirosin, neomycin and ribostamycin. Works in combination with EC 2.6.1.93, neamine transaminase, to replace the 6'-hydroxy group of paromamine with an amino group. The enzyme from the bacterium Streptomyces fradiae also catalyses EC 1.1.3.44, 6'''-hydroxyneomycin C oxidase. Group: Enzymes. Synonyms: btrQ (gene name); neoG (gene name); kanI (gene name); tacB (gene name); neoQ (obsolete gene name). Enzyme Commission Number: EC 1.1.3.43. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0416; paromamine 6'-oxidase; EC 1.1.3.43; btrQ (gene name); neoG (gene name); kanI (gene name); tacB (gene name); neoQ (obsolete gene name). Cat No: EXWM-0416.
primary-amineoxidase
A group of enzymes that oxidize primary monoamines but have little or no activity towards diamines, such as histamine, or towards secondary and tertiary amines. They are copper quinoproteins (2,4,5-trihydroxyphenylalanine quinone) and, unlike EC 1.4.3.4, monoamineoxidase, are sensitive to inhibition by carbonyl-group reagents, such as semicarbazide. In some mammalian tissues the enzyme also functions as a vascular-adhesion protein (VAP-1). Group: Enzymes. Synonyms: amineoxidase (ambiguous); amineoxidase (copper-containing); amineoxidase (pyridoxal containing). Enzyme Commission Number: EC 1.4.3.21. AmineOxidase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1476; primary-amineoxidase; EC 1.4.3.21; amineoxidase (ambiguous); amineoxidase (copper-containing); amineoxidase (pyridoxal containing) (incorrect); benzylamineoxidase (incorrect); CAO (ambiguous); copper amineoxidase (ambiguous); Cu-amineoxidase (ambiguous); Cu-containing amineoxidase (ambiguous); diamineoxidase (incorrect); diamino oxhydrase (incorrect); histamine deaminase (ambiguous); histamineoxidase (ambiguous); monoamineoxidase (ambiguous); plasma monoamineoxidase (ambiguous); polyamineoxidase (ambiguous); semicarbazide-sensitive amineoxidase (ambiguous); SSAO (ambiguous). Cat No: EXWM-1476.
1-[4- (Aminomethyl) phenyl]ethanone Hydrochloride
1-[4- (Aminomethyl) phenyl]ethanone Hydrochloride is used in the structure-?function studies of substrate oxidation by bovine serum amineoxidase. Group: Biochemicals. Grades: Highly Purified. CAS No. 66522-66-5. Pack Sizes: 100mg, 250mg. Molecular Formula: C9H11NO; HCl, Molecular Weight: 149.193646. US Biological Life Sciences.
Worldwide
1-Aminoacetone Hydrochloride
Aminoacetone is a threonine and glycine catabolite that can be converted to methylglyoxal by amineoxidases.1 It has been identified as one of several endogenous sources of methylglyoxal found in the plasma of diabetes patients.2 As a pro-oxidant, 0.10-5 mM aminoacetone can induce cell death in RINm5f pancreatic β-cells.2 Aminoacetone is used as a growth substrate for Pseudomonas.3. Group: Biochemicals. Alternative Names: 1-Amino-2-propanone Hydrochloride; 2-Oxopropylammonium Chloride; Aminoacetone Hydrochloride. Grades: Highly Purified. CAS No. 7737-17-9. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C3H8ClNO, Molecular Weight: 109.55. US Biological Life Sciences.
Worldwide
2-Butynylamine Hydrochloride
2-Butynylamine Hydrochloride is a useful reagent in the study of selective inhibition of bovine plasma amineoxidase by homopropargylamine. Group: Biochemicals. Grades: Highly Purified. CAS No. 50329-23-2. Pack Sizes: 50mg, 100mg. Molecular Formula: C4H7N; HCl, Molecular Weight: 69.113646. US Biological Life Sciences.
Worldwide
3-Butyn-2-ol
3-Butyn-2-ol is an intermediate used to prepare aminoindanes with inhibitory activity toward acetylcholine esterase and monoamineoxidase useful as anti-Alzheimer's agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 2028-63-9. Pack Sizes: 1g, 5g. Molecular Formula: C4H6O, Molecular Weight: 70.09. US Biological Life Sciences.
Worldwide
3-(Methylamino)-propanenitrile
Aminoproponitriles can be used as inhibitors of oxidase enzymes and as a reagent for aminomethylphosphine ligands or the synthesis of aminobenzothiazoles. Group: Biochemicals. Alternative Names: (2-Cyanoethyl) methylamine; 3- (Methylamino) propanenitrile; 3- (Methylamino) propionitrile; 3- (N-Methylamino) propionitrile; 3- methyl aminopropiononitrile; Methyl(2-cyanoethyl)amine; N-(2-Cyanoethyl)-N-methylamine; N- (2-Cyanoethyl) methylamine; N-( β -Cyanoethyl) methylamine; N-Methyl-2-cyanoethylamine; N-Methyl-N-(2-cyanoethyl)amine; N-Methyl- β-alaninenitrile; N-Methyl- β-aminopropionitrile; NSC 8399; β - (Methylamino) propionitrile. Grades: Highly Purified. CAS No. 693-05-0. Pack Sizes: 1g. US Biological Life Sciences.
A building block in the preparation of Rasagiline.Rasagiline is an irreversible inhibitor of monoamineoxidase-B. It can be used as a monotherapy to treat symptoms in early Parkinson's disease or as an adjunct therapy in more advanced cases. Synonyms: 3-keto-Npropargyl-1-aminoindan. Grades: > 95%. Molecular formula: C12H11NO. Mole weight: 185.23.
4-(Aminomethyl)pyridine
4-(Aminomethyl)pyridine is a compound that has derivatives that act as reversible inhibitors of various copper amineoxidases (CAOs). Group: Biochemicals. Alternative Names: 4-Pyridinemethanamine; 1-(Pyridin-4-yl)methanamine; 4-Picolinamine; 4-Picolinylamine; 4-Picolylamine; 4-Pyridinemethylamine; 4-Pyridinylmethanamine; 4-Pyridylmethylamine; C-(Pyridin-4-yl)methylamine; N-[ (4-Pyridinyl) methyl]amine; NSC 59707; Pyridin-4-ylmethylamine; γ-(Aminomethyl)pyridine; γ-Picolylamine; γ-Pyridylmethylamine. Grades: Highly Purified. CAS No. 3731-53-1. Pack Sizes: 5g. US Biological Life Sciences.
Worldwide
5-Amino-1,10-phenanthroline
1,10-Phenanthrolin-5-amine is a potential fluorescent label for DNA detection. 1,10-Phenanthrolin-5-amine is used as a mediator for glucose oxidase for development of biosensors and biofuel cells. Group: Phenanthrolines. Alternative Names: 1,10-Phenanthrolin-5-amine. CAS No. 54258-41-2. Molecular formula: C12H9N3. Mole weight: 195.23. Appearance: White to Amber powder to crystal. Purity: >98.0%(GC). IUPACName: 1,10-phenanthrolin-5-amine. Canonical SMILES: C1=CC2=CC(=C3C=CC=NC3=C2N=C1)N. Catalog: ACM54258412.
5-Amino-1,10-phenanthroline
5-Amino-1,10-phenanthroline. Uses: 1,10-phenanthrolin-5-amine is a potential fluorescent label for dna detection. 1,10-phenanthrolin-5-amine is used as a mediator for glucose oxidase for development of biosensors and biofuel cells. Group: Ligands for functional metal complexessmall molecule semiconductor building blocks. Alternative Names: 1,10-Phenanthrolin-5-amine. CAS No. 54258-41-2. Product ID: 1,10-phenanthrolin-5-amine. Molecular formula: 195.23. Mole weight: C12H9N3. C1=CC2=CC(=C3C=CC=NC3=C2N=C1)N. InChI=1S / C12H9N3 / c13-10-7-8-3-1-5-14-11 (8) 12-9 (10) 4-2-6-15-12 / h1-7H, 13H2. DKPSSMOJHLISJI-UHFFFAOYSA-N. >98.0%(GC).
M 30 dihydrochloride is a potent and brain selective inhibitor of monoamineoxidase (MAO) with EC50 values of 37 and 57 nM for MAO-A and MAO-B, respectively. M 30 decreases cell death rates and apoptotic DNA damage, exhibiting neuroprtective properties. Synonyms: 5-[[methyl(prop-2-ynyl)amino]methyl]-8-quinolinol;dihydrochloride; 5-[[methyl(prop-2-ynyl)amino]methyl]quinolin-8-ol;dihydrochloride. Grades: ≥ 98 % by HPLC. CAS No. 64821-19-8. Molecular formula: C14H16Cl2N2O. Mole weight: 299.20.
(6-Aminohexyl) trimethylammonium Bromide is a potent inhibitor and acts as substrate for pig kidney diamineoxidase. Group: Biochemicals. Alternative Names: 6-Amino-N,N,N-trimethyl-1-hexanaminium Bromide Hydrobromide. Grades: Highly Purified. CAS No. 33968-67-1. Pack Sizes: 10mg. US Biological Life Sciences.
(6-Aminohexyl) trimethylammonium Chloride is a potent inhibitor and acts as substrate for pig kidney diamineoxidase. Group: Biochemicals. Alternative Names: 6-Amino-N,N,N-trimethyl-1-hexanaminium Chloride Hydrochloride. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
6'''-hydroxyneomycin C oxidase
Contains FAD. Involved in the biosynthetic pathway of aminoglycoside antibiotics of the neomycin family. Works in combination with EC 2.6.1.95, neomycin C transaminase, to replace the 6'''-hydroxy group of 6'''-hydroxyneomycin C with an amino group.Also catalyses EC 1.1.3.43, paromamine 6'-oxidase. Group: Enzymes. Synonyms: neoG (gene name); neoQ (obsolete gene name). Enzyme Commission Number: EC 1.1.3.44. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0417; 6'''-hydroxyneomycin C oxidase; EC 1.1.3.44; neoG (gene name); neoQ (obsolete gene name). Cat No: EXWM-0417.
Aminoacetone hydrochloride
Aminoacetone hydrochloride is the simplest monopeptide. Aminoacetone hydrochloride is an intermediate in the metabolism of threonine and glycine. Aminoacetone hydrochloride is an endogenous substrate for semicarbazide-sensitive amineoxidase ( SSAO ), and can be used for determination of SSAO activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 7737-17-9. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W004850.
Aminoguanidine hydrochloride
Aminoguanidine hydrochloride (Pimagedine hydrochloride) is an inhibitor of diamineoxidase and nitric oxide synthase. Aminoguanidine hydrochloride has a dose-dependent inhibitory effect on apoptosis induced by Doxorubicin (HY-15142). Aminoguanidine hydrochloride has antioxidant properties. Aminoguanidine hydrochloride can be used in diabetic nephropathy research [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Pimagedine hydrochloride; GER-11; Aminoguanidinium chloride. CAS No. 1937-19-5. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1041.
CAY10680
The monoamineoxidases A and B are the products of two abutting X-linked genes, and play an important role in the metabolism of biogenic amines in the central nervous system. Inhibition of MAO-B is considered as a strategy to treat Parkinson's disease. CAY10680 is a benzothiazinone compound that selectively inhibits MAO-B with IC50 = 34.9 nM in human. The blockade of adenosine A2A receptors has emerged as a potential treatment for Parkinson's disease. CAY10680 has been shown to abolish cAMP accumulation in CHO cells transfected with adenosine A2A receptors. It can selectively inhibits with Ki of 39.5 nM in human. Synonyms: CAY 10680; CAY-10680. Grades: ≥98%. CAS No. 1439488-21-7. Molecular formula: C18H16N2O2S. Mole weight: 324.4.
cis-2-Phenylcyclopropane carbohydrazide
cis-2-Phenylcyclopropane carbohydrazide can be used with a series of other derivatives of 2-?phenylcyclopropyl amine and analogs in order to study relationships between chemical structure and monoamineoxidase-?inhibiting activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 17364-52-2. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C10H12N2O, Molecular Weight: 176.22. US Biological Life Sciences.
Worldwide
Colesevelam Aminoquat Impurity HBr
(6-Aminohexyl)trimethylammonium Bromide is a potent inhibitor and acts as substrate for pig kidney diamineoxidase. Synonyms: (6-Aminohexyl)trimethylammonium Bromide Hydrobromide. Grades: > 95%. CAS No. 33968-67-1. Molecular formula: C9H24N2Br2. Mole weight: 320.11.
D-Alanine
Alanine is a non essential amino acid. Uses: D-alanine has been used: as an amine donor for ω-transaminase mediated (r)-amination as a substrate for the treatment of d-amino acid oxidase (daao )-transfected cells to measure the heat capacity of l-alanine single crystal. Group: Amino acids. Alternative Names: (R)-2-Aminopropionic acid. CAS No. 338-69-2. Molecular formula: CH3CH(NH2)CO2H. Mole weight: 89.09. Canonical SMILES: C[C@@H](N)C(O)=O. ECNumber: 206-418-1. Catalog: ACM338692-1.
dopamine β-monooxygenase
A copper protein. Stimulated by fumarate. Group: Enzymes. Synonyms: dopamine β-hydroxylase; MDBH (membrane-associated dopamine β-monooxygenase); SDBH (soluble dopamine β-monooxygenase); dopamine-B-hydroxylase; 3,4-dihydroxyphenethylamine β-oxidase; 4-(2-aminoethyl)pyrocatechol β-oxidase; dopa β-hydroxylase; dopamine β-oxidase; dopamine hydroxylase; phenylamine β-hydroxylase; (3,4-dihydroxyphenethylamine)β-mono-oxygenase; DβM (gene name). Enzyme Commission Number: EC 1.14.17.1. CAS No. 9013-38-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0960; dopamine β-monooxygenase; EC 1.14.17.1; 9013-38-1; dopamine β-hydroxylase; MDBH (membrane-associated dopamine β-monooxygenase); SDBH (soluble dopamine β-monooxygenase); dopamine-B-hydroxylase; 3,4-dihydroxyphenethylamine β-oxidase; 4-(2-aminoethyl)pyrocatechol β-oxidase; dopa β-hydroxylase; dopamine β-oxidase; dopamine hydroxylase; phenylamine β-hydroxylase; (3,4-dihydroxyphenethylamine)β-mono-oxygenase; DβM (gene name). Cat No: EXWM-0960.
(E)-N-Methylcinnamylamine
(E)-N-Methylcinnamylamine is an 3-amino-1-phenyl-prop-1-ene derivative with potential to inhibit and inactivate monoamineoxidase. Group: Biochemicals. Alternative Names: (2E)-N-Methyl-3-phenyl-2-propen-1-amine; (E)-N-Methyl-3-phenyl-2-propen-1-amine. Grades: Highly Purified. CAS No. 116939-14-1. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
flavin-containing monooxygenase
A flavoprotein. A broad spectrum monooxygenase that accepts substrates as diverse as hydrazines, phosphines, boron-containing compounds, sulfides, selenides, iodide, as well as primary, secondary and tertiary amines. This enzyme is distinct from other monooxygenases in that the enzyme forms a relatively stable hydroperoxy flavin intermediate. This microsomal enzyme generally converts nucleophilic heteroatom-containing chemicals and drugs into harmless, readily excreted metabolites. For example, N-oxygenation is largely responsible for the detoxification of the dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Group: Enzymes. Synonyms: dimethylanilin...CAS No. 37256-73-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0887; flavin-containing monooxygenase; EC 1.14.13.8; 37256-73-8; dimethylaniline oxidase; dimethylaniline N-oxidase; FAD-containing monooxygenase; N,N-dimethylaniline monooxygenase; DMA oxidase; flavin mixed function oxidase; Ziegler's enzyme; mixed-function amineoxidase; FMO; FMO-I; FMO-II; FMO1; FMO2; FMO3; FMO4; FMO5; flavin monooxygenase; methylphenyltetrahydropyridine N-monooxygenase; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine:oxygen N-oxidoreductase; dimethylaniline monooxygenase (N-oxide-forming). Cat No: EXWM-0887.
Fructosyl-Amino Acid Oxidase from Corynebacterium sp., Recombinant
Fructosamines are formed when glucose is condensed amino group of amino acids or proteins. Fructosamineoxidases (FAOX) catalyze the oxidative deglycation of low molecular weight fructosamines. Fructosyl amino acid oxidase catalyzes the oxidation of the C-N bond linking the C1 of the fructosyl moiety and the nitrogen of the amino group of fructosyl amino acids. Enzyme commission (e.c.) 1.5.3.x, fructosyl amino acid oxidase [fructosyl-a-l-amino acid:oxygen oxidoreductase] is a flavoprotein that catalyzes the oxidation of fructosyl amino acids to form glucosone, amino acid and hydrogen peroxide. Applications: Fructosyl-amino acid oxidase can be used to detect the levels of glycated proteins, which are markers for diabetes mellitus. Group: Enzymes. Synonyms: Fructosyl-Amino Acid Oxidase. Fructosyl-amino acid oxidase. Mole weight: mol wt ~88 kDa by electrophoresis. Activity: > 0.45 units/mg protein. Storage: -20°C. Form: lyophilized powder. Source: E. coli. Species: Corynebacterium sp. Fructosyl-Amino Acid Oxidase. Cat No: NATE-0258.
Fructosyl-Amino Acid Oxidase from E. coli, Recombinant
Fructosamines are formed when glucose is condensed amino group of amino acids or proteins. Fructosamineoxidases (FAOX) catalyze the oxidative deglycation of low molecular weight fructosamines. Fructosyl amino acid oxidase catalyzes the oxidation of the C-N bond linking the C1 of the fructosyl moiety and the nitrogen of the amino group of fructosyl amino acids. Group: Enzymes. Synonyms: Fructosyl-amino acid oxidase. Fructosyl-amino acid oxidase. Mole weight: ca. 45 kDa. Activity: > 4 U/mg lyophilizate. Appearance: Yellow lyophilizate. Storage: at -20°C. Source: E. coli. Species: E. coli. Fructosyl-L-amino acid : oxygen oxidoreductase; EC 1.5.3.; Fructosyl-amino acid oxidase. Cat No: DIA-409.
Fructosyl-peptide Oxidase from E. coli, Recombinant
The fructosyl peptide oxidase is an enzyme that catalyzes the reaction which produces a sugar osone (an α-keto aldehyde), a peptide, and hydrogen peroxide by oxidative cleaving, in the presence of oxygen molecules, the C--N bond in the ketose derivative produced by Amadori rearrangement of glucosylamine produced by the reaction between the hemiacetal of glucose and the N-terminal amino group of a peptide. Group: Enzymes. Synonyms: Fructosyl-peptide : oxygen oxidoreductase; EC 1.5.3; Fructosyl-peptide Oxidase. Enzyme Commission Number: EC 1.5.3. Fructosyl-peptide Oxidase. Mole weight: ca. 60 kDa. Activity: > 4 U/mg lyophilizate. Stability: Stable at 37°C for at least one month. Appearance: Yellow lyophilizate. Storage: at -20°C. Source: E. coli. Species: E. coli. Fructosyl-peptide : oxygen oxidoreductase; EC 1.5.3; Fructosyl-peptide Oxidase. Cat No: DIA-410.
Glycine Oxidase H244K from Bacillus subtilis, recombinant
Glycine oxidase (GO) from Bacillus subtilis (EC 1.4.3.19) is a homotetrameric flavin-dependent oxidoreductase. Each GO monomer is non-covalently bound to flavin adenine dinucleotide. GO catalyzes oxidative deamination of various primary and secondary amines (e.g. glycine, sarcosine, N-ethylglycine) and some D-amino acids (e.g. D -alanine, D -proline, D -valine) to the corresponding α-keto acids and hydrogen peroxide. Primarily, glycine oxidase catalyzes the oxidation of glycine in the biosynthesis of thiamine. The variant H244K shows a higher substrate specificity ratio for glycine versus sarcosine and a 5-fold improved specific activity in comparison to the wild-type. Group: Enzymes. Synonyms: Glycine oxidase; glycine oxygen oxidoreductase (deaminating); GO; EC 1.4.3.19; 39307-16-9. Enzyme Commission Number: EC 1.4.3.19. CAS No. 39307-16-9. Purity: > 90% by SDS-PAGE. Mole weight: 43.1 kDa (1-369 aa, NT His Tag). Activity: 1200 mU/mg. Storage: Store at -20°C. Stable for at least 1 year as supplied. Avoid repeated freeze and thaw cycles. Form: Liquid. Source: E. coli. Species: Bacillus subtilis. Glycine oxidase; glycine oxygen oxidoreductase (deaminating); GO; EC 1.4.3.19; 39307-16-9. Cat No: NATE-1674.
Hydralazine-D4 Hydrochloride
Hydralazine-D4 Hydrochloride is the labeled version of Hydralazine Hydrochloride (H716531), which is a non-nucleoside analog that inhibits DNA methylation and reactivates the expression of tumor suppressor genes (1,2,3). It is also a non-selective MAO-A/B inhibitor and a semicarbazide-sensitive amineoxidase inhibitor and antihypertensive. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C8H4D4N4; HCl, Molecular Weight: 164.203645999999. US Biological Life Sciences.
Worldwide
Hydralazine Hydrochloride
Hydralazine is a non-nucleoside analog that inhibits DNA methylation and reactivates the expression of tumor suppressor genes. Non-selective MAO-A/B inhibitor; semicarbazide-sensitive amineoxidase inhibitor. Antihypertensive. Group: Biochemicals. Alternative Names: 1-Hydrazinylphthalazine Hydrochloride; 1(2H)-Phthalazinone Hydrazone Hydrochloride; 1-Phthalazinylhydrazine Hydrochloride; Apresoline Hydrochloride; Apulon; Hydralazine Chloride; Hydralazine Monohydrochloride; Lopres. Grades: Highly Purified. CAS No. 304-20-1. Pack Sizes: 10g. US Biological Life Sciences.
Worldwide
Isocarboxazid
Isocarboxazid is a non-selective, irreversible monoamineoxidase inhibitor (MAOI) belonging to the hydrazine class. It is primarily used to treat mood and anxiety disorders. It is also used for the treatment of Parkinson's disease and other dementia-related disorders. It is also effective in the treatment of major depression, dysthymic disorder, and atypical depression. It blocks the breakdown (oxidative deamination) of biogenic amines by inhibiting MAO, thereby increasing the concentrations of norepinephrine and 5-hydroxytrytamine at central aminergic receptors. It was developed by Validus and has been listed. Uses: Isocarboxazid is primarily used to treat mood and anxiety disorders. it is also used for the treatment of parkinson's disease and other dementia-related disorders. it is also effective in the treatment of major depression, dysthymic disorder, and atypical. Synonyms: 1-Benzyl-2-(5-methyl-3-isoxazolylcarbonyl)hydrazine;3-Isoxazolecarboxylic acid, 5-methyl-, 2-(phenylmethyl)hydrazide;3-Isoxazolecarboxylic acid, 5-methyl-, 2-benzylhydrazide;5-Methyl-3-isoxazole-carboxylic Acid 2-Benzylhydrazide;3-(N-Benzylhydrazinocarbon. Grades: 95%. CAS No. 59-63-2. Molecular formula: C12H13N3O2. Mole weight: 231.25.
Kynuramine dihydrochloride
Kynuramine, an endogenously occurring amine, is a fluorescent substrate and probe of plasma amineoxidase [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 36681-58-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-119395B.
laccase
A group of multi-copper proteins of low specificity acting on both o- and p-quinols, and often acting also on aminophenols and phenylenediamine. The semiquinone may react further either enzymically or non-enzymically. Group: Enzymes. Synonyms: urishiol oxidase; urushiol oxidase; p-diphenol oxidase. Enzyme Commission Number: EC 1.10.3.2. CAS No. 80498-15-3. Laccase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0482; laccase; EC 1.10.3.2; 80498-15-3; urishiol oxidase; urushiol oxidase; p-diphenol oxidase. Cat No: EXWM-0482.
Ladostigil
Ladostigil, also called as TV-3,326, is a novel neuroprotective agent developed to treat neurodegenerative disorders sunch as Alzheimer's disease. Ladostigil is a dual acetylcholine-butyrylcholineesterase and brain selective monoamineoxidase (MAO)-A and -B inhibitor in vivo (with little or no MAO inhibitory effect in the liver and small intestine). Synonyms: [(3R)-3-(prop-2-ynylamino)-2,3-dihydro-1H-inden-5-yl] N-ethyl-N-methylcarbamate; (N-propargyl-(3R) aminoindan-5-yl)-ethyl methyl carbamate; Ladostigil; TV 3326; TV3326; TV-3326. Grades: >98%. CAS No. 209394-27-4. Molecular formula: C16H20N2O2. Mole weight: 272.348.
Lazabemide hydrate
Lazabemide, a pyridine derivative, is a reversible and selective monoamineoxidase B inhibitor that has probable effect for Parkinson's disease. IC50: 30 nM. It could also influence the absorption of some monoamines like noradrenalin, serotonin and dopami. Uses: Lazabemide is a reversible and selective monoamineoxidase b inhibitor that has probable effect against parkinson's disease. Synonyms: Lazabemide; Cardaptive; MK-0524; MK 0524; MK0524; Laropiprant; N-(2-Aminoethyl)-5-chloro-2-pyridinecarboxamide hydrate, Ro 19-6327 hydrate. Grades: 95%. CAS No. 103878-84-8. Molecular formula: C8H10ClN3O. Mole weight: 199.64 (anhydrous basis).
Lazabemide hydrochloride
Lazabemide is a monoamineoxidase B inhibitor with IC50 values of 0.03 and > 100 μM for MAO-B and MAO-A. It is potentially an antiparkinsonian agent. Uses: Antiparkinson agents. Synonyms: N-(2-Aminoethyl)-5-chloro-2-pyridinecarboxamide hydrochloride. Grades: ≥98% by HPLC. CAS No. 103878-83-7. Molecular formula: C8H10ClN3O.HCl. Mole weight: 236.1.
L-lysine 6-oxidase
Differs from EC 1.4.3.13, protein-lysine 6-oxidase, by using free L-lysine rather than the protein-bound form. N2-Acetyl-L-lysine is also a substrate, but N6-acetyl-L-lysine, which has an acetyl group at position 6, is not a substrate. Also acts on L-ornithine, D-lysine and 4-hydroxy-L-lysine, but more slowly. The amines cadaverine and putrescine are not substrates. Group: Enzymes. Synonyms: L-lysine-ε-oxidase; Lod; LodA; marinocine. Enzyme Commission Number: EC 1.4.3.20. CAS No. 1116448-48-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1475; L-lysine 6-oxidase; EC 1.4.3.20; 1116448-48-6; L-lysine-ε-oxidase; Lod; LodA; marinocine. Cat No: EXWM-1475.
LSD1 Inhibitor IV, RN-1,HCl (2- (1R, 2S) -2- (4- (Benzyloxy) phenyl) cyclopropylamino) -1- (4-methylpiperazin-1-yl) ethanone, HCl, Lysine (K)-Specific Demethylase Inhibitor IV,RN-1,HCl, BHC110 Inhibitor IV, KDM1 Inhibitor IV, MOA Inhibitor III)
A cell-permeable tranylcypromine (parnate) analog that acts as a potent, irreversible inhibitor of lysine specific demethylase 1 (LSD1; IC50=70nM in a HRP-coupled assay using H3K4Me2 peptide substrate). Forms a covalent adduct with flavin adenine dinucleotide (FAD). Shown to cross the blood brain barrier. Exhibits moderate selectivity over amineoxidases MAO-A and MAO-B (IC50=0.51 and 2.785uM, respectively). Displays desirable pharmacokinetic properties (brain/plasma exposure ratio of 88.9), and impairs long-term memory without affecting short-term memory in mice (10mg/kg, i.p.). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
L-Tryptophan
Amino acids-type drug: It can be used in amino acid infusion, being often combined with iron and vitamins. Its co-administration with VB6 can improve depression and prevention/treatment of skin disease; as a sleep sedative, it can be combined with L-dopa for the treatment of Parkinson's disease. It is carcinogenic to experimental animals; it may cause adverse reactions including nausea, anorexia and asthmas. Avoid combination with monoamineoxidase inhibitors. Nutritional supplements: Tryptophan contained in egg white protein, fish meat, corn meal and other amino acids are limited; content in cereals such as rice is also low. It can be combined with lysine, methionine and threonine for enhanced amino acids. It can be supplemented to corn product at the content of 0.02% tryptophan and 0.1% lysine, being capable of significantly improving the protein potency.tryptophan is one of the 21 amino acids comprising a protein. Tryptophan is a component of the skin's natural moisturizing factors. Group: Heterocyclic organic compound. Alternative Names: L-Beta-3-indolylalanine. CAS No. 73-22-3. Molecular formula: C11H12N2O2. Mole weight: 204.23. Appearance: White to yellow-white powder. Purity: 0.99. IUPACName: (2S)-2-Amino-3-(1H-indol-3-yl)propanoic acid. Canonical SMILES: C1=CC=C2C(=C1)C(=CN2)CC(C(=O)O)N. Density: 1.34 g/cm³. ECNumber: 200-795-6. Catalog: ACM73223.
(+)-N 0425 hydrochloride
(+)-N 0425 hydrochloride is a monoamineoxidase (MAO) inhibitor with selectivity for MAO-B. Synonyms: N 0425 hydrochloride; N0425 hydrochloride; N-0425 hydrochloride; N-methyl-N-prop-2-ynyl-1,2,3,4-tetrahydronaphthalen-2-amine hydrochloride. Grades: 99%. CAS No. 98640-74-5. Molecular formula: C14H17N.HCl. Mole weight: 235.75.
N 0425 hydrochloride
N 0425 hydrochloride is a potent monoamineoxidase (MAO) inhibitor. Synonyms: N 0425 hydrochloride; N0425 hydrochloride; N-0425 hydrochloride; N-methyl-N-prop-2-ynyl-1,2,3,4-tetrahydronaphthalen-2-amine hydrochloride. Grades: 99%. CAS No. 78621-26-8. Molecular formula: C14H17N.HCl. Mole weight: 235.75.
N 0430 hydrobromide
N 0430 hydrobromide is a monoamineoxidase (MAO) inhibitor and a dopamine agonist. Synonyms: N 0430 hydrobromide; N0430 hydrobromide; N-0430 hydrobromide; 6-[methyl(prop-2-ynyl)amino]-5,6,7,8-tetrahydronaphthalene-1,2-diol hydrobromide. Grades: 99%. CAS No. 96333-04-9. Molecular formula: C14H17NO2.HBr. Mole weight: 312.2.
N 0432 hydrobromide
N 0432 hydrobromide is a monoamineoxidase (MAO) inhibitor and a dopamine agonist. Synonyms: N 0432 hydrobromide; N0432 hydrobromide; N-0432 hydrobromide; 6-[methyl(prop-2-ynyl)amino]-5,6,7,8-tetrahydronaphthalene-2,3-diol hydrobromide. Grades: 96%. CAS No. 96333-05-0. Molecular formula: C14H17NO2.HBr. Mole weight: 312.2.
N-(2-Aminoethyl)-4-chlorobenzamide Hydrochloride
A competitive, time-dependent reversible inhibitor of monamineoxidase-B (MAO-B) is also an analogue of N-(2-Aminoethyl)benzamide. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
N-2-Propynyl Rasagiline Hydrochloride
An impurity of Rasagiline.Rasagiline is an irreversible inhibitor of monoamineoxidase-B. It can be used as a monotherapy to treat symptoms in early Parkinson's disease or as an adjunct therapy in more advanced cases. Synonyms: N-2-Propynyl Rasagiline Hydrochloride; 10409-00-4; N,N-bis(prop-2-ynyl)-2,3-dihydro-1H-inden-1-amine; hydrochloride; J-001101; N,N-Di(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-amine hydrochloride. Grades: > 95%. Molecular formula: C15H15N. HCl. Mole weight: 245.75.
N-alkylglycine oxidase
Isolated from the mold Cladosporium sp. G-10. Acts on N6-(carboxymethyl)lysine, 6-[(carboxymethy)amino]hexanoic acid, sarcosine and N-ethylglycine. It has negligible action on glycine (cf. EC 1.4.3.19 glycine oxidase). Group: Enzymes. Synonyms: N-carboxymethylalkylamine:oxygen oxidoreductase (decarboxymethylating). Enzyme Commission Number: EC 1.5.3.20. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1548; N-alkylglycine oxidase; EC 1.5.3.20; N-carboxymethylalkylamine:oxygen oxidoreductase (decarboxymethylating). Cat No: EXWM-1548.
Native Bacillus sp. Sarcosine Oxidase
Sarcosine oxidase is an enzyme (EC 1.5.3.1) that catalyzes the oxidative demethylation of sarcosine to yield glycine, H2O2, 5,10-CH2-tetrahydrofolate in a reaction requiring H4-tetrahydrofolate and oxygen. Corynebacterial sarcosine oxidase is a heterotetramer and is produced as an inducible enzyme when Corynebacterium sp.is grown with sarcosine as source of carbon and energy. Monomeric sarcosine oxidase (msox) is a flavoenzyme that catalyzes the oxidative demethylation of sarcosine (n-methylglycine) to yield glycine, formaldehyde, and hydrogen peroxide. monomeric sarcosine oxidase can oxidize other secondary amino acids such as n-methyl-l-alanine, n-ethylglycine, and l-proline. Applications: Sarcosine oxidase has been used in a study as part of a multienzyme cascade, that when immobilized constructed amperometric biosensors. sarcosine oxidase has also been used in a study to investigate oxidation of amines by flavoproteins. Group: Enzymes. Synonyms: Sarcosine oxidase; EC 1.5.3.1; 9029-22-5; sarcosine:oxygen oxidoreductase (demethylating). Enzyme Commission Number: EC 1.5.3.1. CAS No. 9029-22-5. SAO. Activity: 25-50 units/mg solid. Storage: -20°C. Form: lyophilized powder; No stabilizers added. Source: Bacillus sp. Sarcosine oxidase; EC 1.5.3.1; 9029-22-5; sarcosine:oxygen oxidoreductase (demethylating). Cat No: NATE-0664.
Native Laccase from White rot fungi
Laccase (Laccase E.C. 1. 10. 3. 2) is a glucoproteinase containing copper. It can catalyze phenols and its derivatives, aromatic amine and its derivatives, carboxylic acids and its derivatives, steroid hormone, biochrome, organometallic compounds and non-phenols substrate. Applications: For indigo-dye-fading technique of jean processing by using laccase and catalysis enzymes in jean-washing industry, for selectively catalyze lignin-degradation and pulp bleaching by using laccase combined medium and xylanase. it is also a new environment friendly technique in wastepaper deinking process. for chlorophenols organic compounds degradation of wastewater treatment (which in line with ph requirements of laccase). for baking. for extract sugar. it can raise color value remaining. for others using as fiberboard adhesive, hair dyeing, lacquer dyeing film formation, crosslinking agent and biological measurement. Group: Enzymes. Synonyms: Laccases; EC 1.10. CAS No. 80498-15-3. Laccase. Activity: 10,000u/ml. Stability: 6 months at 5°C, activity remain ≥90%. Increase dosage after shelf life. Appearance: Liquid. Storage: Should be stored in a cool place to avoid effect of high temperature. Source: White rot fungi. Laccases; EC 1.10.3.2; 80498-15-3; urishiol oxidase; urushiol oxidase; p-diphenol oxidase; benzenediol:oxygen oxidoreductase. Cat No: NATE-1021.
neamine transaminase
The reaction occurs in vivo in the opposite direction. Involved in the biosynthetic pathways of several clinically important aminocyclitol antibiotics, including kanamycin B, butirosin, neomycin and ribostamycin. Works in combination with EC 1.1.3.43, paromamine 6-oxidase, to replace the 6'-hydroxy group of paromamine with an amino group. The enzyme from the bacterium Streptomyces kanamyceticus can also catalyse EC 2.6.1.94, 2'-deamino-2'-hydroxyneamine transaminase, which leads to production of kanamycin A. The enzyme from the bacterium Streptomyces fradiae can also catalyse EC 2.6.1.95, leading to production of neomycin C. Group: Enzymes. Synonyms: glutamate-6'-dehydroparomamine aminotransferase; btrB (gene name); neoN (gene name); kacL (gene name). Enzyme Commission Number: EC 2.6.1.93. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2934; neamine transaminase; EC 2.6.1.93; glutamate-6'-dehydroparomamine aminotransferase; btrB (gene name); neoN (gene name); kacL (gene name). Cat No: EXWM-2934.
neomycin C transaminase
The reaction occurs in vivo in the opposite direction. Involved in the biosynthetic pathway of aminoglycoside antibiotics of the neomycin family. Works in combination with EC 1.1.3.44, 6'''-hydroxyneomycin C oxidase, to replace the 6'''-hydroxy group of 6'''-deamino-6'''-hydroxyneomycin C with an amino group.The enzyme, characterized from the bacterium Streptomyces fradiae, can also catalyse EC 2.6.1.93, neamine transaminase. Group: Enzymes. Synonyms: neoN (gene name). Enzyme Commission Number: EC 2.6.1.95. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2936; neomycin C transaminase; EC 2.6.1.95; neoN (gene name). Cat No: EXWM-2936.
N-Methylpropargylamine
N-Methylpropargylamine is a metabolite of Pargyline. N-Methylpropargylamine, like other propynylamine, has inhibitory effect on monoamineoxidase. Group: Biochemicals. Alternative Names: 3-Methylaminoprop-1-yne; Methyl(2-propynyl)amine; Methyl (propargyl)amine; N-(2-Propynyl)methylamine; N-Methyl-2-propyn-1-amine; N-Methyl-N-2-propynylamine; N-Methyl-N-propargylamine; NSC 56897. Grades: Highly Purified. CAS No. 35161-71-8. Pack Sizes: 2.5g. US Biological Life Sciences.
Worldwide
O- (2, 4-Dinitrophenyl) hydroxylamine
O- (2, 4-Dinitrophenyl) hydroxylamine is a rapid active-site-directed inhibitor of D-amino acid oxidase; modification results in specific incorporation of an amine group into an accessible nucleophilic residue with concomitant release of 2,4-dinitrophenol. Group: Biochemicals. Alternative Names: 1-Aminooxy-2,4-dinitrobenzene; 2,4-Dinitrophenoxyamine; 2,4-Nitrophenoxyamine; DNPA; NSC 148499. Grades: Highly Purified. CAS No. 17508-17-7. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
OG-L002
OG-L002 potently inhibits HSV IE gene expression in both HeLa and HFF cells with IC50s of ~10 μM and ~3 μM, respectively. OG-L002 is a potent and highly selective inhibitor of LSD1 (IC50 = 0.02 μM), and is a potent inhibitor of monoamineoxidases (MAO) with IC50s of 1.38 and 0.72 μM for MAO-A and MAO-B, respectively. Synonyms: 4'-[(1R,2S)-2-Aminocyclopropyl]-[1,1'-biphenyl]-3-ol; 4'-((1R,2S)-2-Aminocyclopropyl)biphenyl-3-ol; [1,1'-Biphenyl]-3-ol, 4'-[(1R,2S)-2-aminocyclopropyl]-; 4'-[(1R,2S)-2-Aminocyclopropyl]-3-biphenylol. Grades: >98%. CAS No. 1357302-64-7. Molecular formula: C15H15NO. Mole weight: 225.29.
Pargyline
Pargyline is a monoamineoxidase B (MAO-B) inhibitor with antihypertensive properties(IC50=8.2 nM), and has been found to bind with high affinity to the I2 imidazoline receptor. Uses: Monoamineoxidase b (mao-b) inhibitor. Synonyms: N-benzyl-N-methylprop-2-yn-1-amine. Grades: ≥ 95 %. CAS No. 555-57-7. Molecular formula: C11H13N. Mole weight: 159.23.
Pargyline hydrochloride
Pargyline hydrochloride, a benzene derivative, is an irreversible monoamineoxidase (MAO) inhibitor that is used clinically to treat moderate hypertension but is less effective than TCAs. Uses: Antihypertensive agents. Synonyms: N-benzyl-N-methylprop-2-yn-1-amine;hydrochloride Hydrochloride, Pargyline Pargyline Pargyline Hydrochloride. Grades: >98%. CAS No. 306-07-0. Molecular formula: C11H14ClN. Mole weight: 195.69.
protein-lysine 6-oxidase
Also acts on protein 5-hydroxylysine. This enzyme catalyses the final known enzymic step required for collagen and elastin cross-linking in the biosynthesis of normal mature extracellular matrices. These reactions play an important role for the development, elasticity and extensibility of connective tissue. The enzyme is also active on free amines, such as cadaverine or benzylamine. Group: Enzymes. Synonyms: lysyl oxidase. Enzyme Commission Number: EC 1.4.3.13. CAS No. 99676-44-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1469; protein-lysine 6-oxidase; EC 1.4.3.13; 99676-44-5; lysyl oxidase. Cat No: EXWM-1469.
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