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An intermediate in the preparation of HIV-integrase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 888504-27-6. Pack Sizes: 10mg. US Biological Life Sciences.
A labeled intermediate in the preparation of labeled HIV-integrase inhibitors. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
An intermediate in the preparation of HIV-integrase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 519032-08-7. Pack Sizes: 25mg. US Biological Life Sciences.
An labeled intermediate in the preparation of labeled HIV-integrase inhibitors. Group: Biochemicals. Alternative Names: 2-(1-Amino-1-methylethyl)-N-[(4-fluorophenyl)methyl]-1,6-dihydro-5-hydroxy-1-(methyl-d3)-6-oxo-4-pyrimidinecarboxamide. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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2,4,5-Triamino-6-hydroxypyrimidine-13C2 Sulfate Salt
2,4,5-Triamino-6-hydroxypyrimidine-13C2 Sulfate Salt is an intermediate used in the preparation of labelled 2-Amino-6,8-dihydroxypurine Hydrochloride (A604920). A labelled substituted 5-aminopyrimidines with antioxidative activity. Group: Biochemicals. Alternative Names: 4,5-Triamino-6-pyrimidinol-13C2 Sulfate Salt; 2,4,5-Triaminopyrimidin-6(1H)-one-13C2 Sulfate Salt; 2,5,6-Triamino-4(1H)-pyrimidone-13C2 Sulfate Salt; 2,5,6-Triamino-4-hydroxypyrimidine-13C2 Sulfate Salt; 2,5,6-Triamino-4-oxopyrimidine-13C2 Sulfate Salt; 2,5,6-Triamino-4-pyrimidinol-13C2 Sulfate Salt; 2,5,6-Triamino-4-pyrimidinone-13C2 Sulfate Salt; 2,5,6-Triaminopyrimidin-4(1H)-one;-13C2 Sulfate Salt; 2,5,6-Triaminopyrimidin-4(3H)-one-13C2 Sulfate Salt; 4-Hydroxy-2,5,6-triaminopyrimidine-13C2 Sulfate Salt; 6-Hydroxy-2,4,5-triaminopyrimidine-13C2 Sulfate Salt; NSC 9313-13C2 Sulfate Salt. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
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2,4-Diamino-6-hydroxypyrimidine
2,4-Diamino-6-hydroxypyrimidine has been found to be a GCH1 inhibitor and could suppress the activity of NO synthase through preventing the synthesis of BH4. Uses: Enzyme inhibitors. Synonyms: 2,6-Diamino-4(1H)-pyrimidinone; 2,6-Diaminopyrimidin-4-one; 6-Aminoisocytosine; NSC 44914; NSC 680818; NSC 9302; 4(3H)-Pyrimidinone, 2,6-diamino-; 2,6-Diamino-4(3H)-pyrimidinone; 4(1H)-Pyrimidinone, 2,6-diamino-; 2,4-Diamino-6-pyrimidinone; 2,6-Diamino-1,4-dihydropyrimidin-4-one; 2,6-Diamino-1H-pyrimidin-4-one; 2,6-Diamino-3,4-dihydropyrimidin-4-one; 2,6-Diamino-3H-pyrimidin-4-one; 2,6-Diamino-4-pyrimidinol; 4-Hydroxypyrimidine-2,6-diamine; 6-Hydroxy-2,4-diaminopyrimidine; 6-Hydroxy-2,4-pyrimidinediamine. Grades: ≥95%. CAS No. 56-06-4. Molecular formula: C4H6N4O. Mole weight: 126.12.
2, 4-Di hydroxy-6-amino-5-diethoxyethyl pyrimidine. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500mg. US Biological Life Sciences.
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2-Amino-4,6-dihydroxypyrimidine
2-Amino-4,6-dihydroxypyrimidine. Group: Biochemicals. Alternative Names: 2-Amino-6-hydroxy-4(3H)-pyrimidinone; 2-Amino-4,6-pyrimidinediol; 2-Amino-4,6-dioxypyrimidine. Grades: Highly Purified. CAS No. 56-09-7. Pack Sizes: 100g, 250g, 500g, 1kg, 2kg. Molecular Formula: C4H5N3O2. US Biological Life Sciences.
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2-Amino-4,6-dihydroxypyrimidine-13C2
2-Amino-4,6-dihydroxypyrimidine-13C2 is an intermediate in the production of antimicrobial guanylsulfonamides. Group: Biochemicals. Alternative Names: 2-Amino-6-hydroxy-4(3H)-pyrimidinone-13C2; 2-Amino-4,6-pyrimidinediol-13C2; 2-Amino-4,6-dioxypyrimidine-13C2; 4,6-Dihydroxy-2-aminopyrimidine-13C2; NSC 15920-13C2; NSC 18692-13C2. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
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2-Amino-4-hydroxy-6-methylpyrimidine
2-Amino-4-hydroxy-6-methylpyrimidine. Uses: Designed for use in research and industrial production. Product Category: Pyrimidines. Appearance: White Powder. CAS No. 3977-29-5. Molecular formula: C5H7N3O. Mole weight: 125.13. Purity: 0.98. Product ID: ACM3977295. Alfa Chemistry ISO 9001:2015 Certified.
2-Amino-4-hydroxy-6-trifluoromethylpyrimidine
2-Amino-4-hydroxy-6-trifluoromethylpyrimidine. Uses: Designed for use in research and industrial production. Product Category: Pyrimidines. Appearance: White to Tan Powder or Crystals. CAS No. 1513-69-5. Molecular formula: C5H4F3N3O. Mole weight: 179.1. Purity: 0.97. Product ID: ACM1513695. Alfa Chemistry ISO 9001:2015 Certified.
2-Amino-4-hydroxy-6- (trifluoromethyl) pyrimidine
2-Amino-4-hydroxy-6- (trifluoromethyl) pyrimidine. Group: Biochemicals. Grades: Reagent Grade. CAS No. 1513-69-5. Pack Sizes: 1g, 5g, 25g, 100g. US Biological Life Sciences.
An inhibitor of enzymes. Group: Biochemicals. Alternative Names: Hydroxy-PP. Grades: Highly Purified. CAS No. 1215573-50-4. Pack Sizes: 5mg. US Biological Life Sciences.
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4-Amino-2-cyanimino-6-hydroxypyrimidine
4-Amino-2-cyanimino-6-hydroxypyrimidine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: MolPort-003-909-476, NSC 27716, CID80203, NSC27716, NSC60204, 2-Cyanamino-4-amino-6-hydroxypyrimidine, NSC 60204, 2-Pyrimidinecarbamonitrile, 4-amino-6-hydroxy-, 4-AMINO-2-CYANIMINO-6- HYDROXYPYRIMIDINE, Cyanamide, (6-amino-1,4-dihydro-4-oxo-2-pyrimidinyl)-, 2-Pyrimidinecarbamonitrile, 4-amino-6-hydroxy- (8CI), 2-Pyrimidinecarbamonitrile, 4-amino-6-hydroxy- (keto form), Cyanamide, N-(4-amino-1,6-dihydro-6-oxo-2-pyrimidinyl)-, 6112-71-6. Product Category: Heterocyclic Organic Compound. CAS No. 6112-71-6. Molecular formula: C5H5N5O. Mole weight: 151.1261. Purity: 0.96. IUPACName: (6-amino-4-oxo-1H-pyrimidin-2-yl)cyanamide. Density: 1.69g/cm³. Product ID: ACM6112716. Alfa Chemistry ISO 9001:2015 Certified.
5-Amino-2,4,6-trihydroxypyrimidine hydrochloride
5-Amino-2,4,6-trihydroxypyrimidine hydrochloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-aminopyrimidine-2,4,6-triol hydrochloride, 5-Amino-2,4,6-trihydroxypyrimidine hydrochloride, 3B3-057150, 66887-61-4. Product Category: Heterocyclic Organic Compound. CAS No. 66887-61-4. Molecular formula: C4H6ClN3O3. Mole weight: 179.561740 [g/mol]. Purity: 0.96. IUPACName: 5-amino-6-hydroxy-1H-pyrimidine-2,4-dione;hydrochloride. Canonical SMILES: C1(=C(NC(=O)NC1=O)O)N.Cl. Product ID: ACM66887614. Alfa Chemistry ISO 9001:2015 Certified.
An impurity of the commercial synthesis of Raltegravir. Group: Biochemicals. Alternative Names: 5-Hydroxy-6-methoxy-2-[1-methyl-1-[[ (phenylmethoxy) carbonyl]amino]ethyl]-4-pyrimidinecarboxylic Acid Methyl Ester. Grades: Highly Purified. CAS No. 1159977-42-0. Pack Sizes: 25mg. US Biological Life Sciences.
An labeled impurity of the commercial synthesis of labeled Raltegravir. Group: Biochemicals. Alternative Names: 5-Hydroxy-6- (methoxy-d3) -2-[1-methyl-1-[[ (phenylmethoxy) carbonyl]amino]ethyl]-4-pyrimidinecarboxylic Acid Methyl Ester. Grades: Highly Purified. CAS No. 1185032-53-4. Pack Sizes: 1mg. US Biological Life Sciences.
5-Methylcytosine Hydrochloride (4-Amino-2-hydroxy-5-methyl-pyrimidine Hydrochloride). Group: Biochemicals. Alternative Names: 4-Amino-2-hydroxy-5-methyl-pyrimidine Hydrochloride. Grades: Highly Purified. Pack Sizes: 500mg. US Biological Life Sciences.
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5-Pyrimidinecarboximidamide,4-amino-N-hydroxy-
5-Pyrimidinecarboximidamide,4-amino-N-hydroxy-. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-Pyrimidinecarboximidamide,4-amino-N-hydroxy-;5-Pyrimidinecarboximidamide,4-amino-N-hydroxy-(9CI). Product Category: Heterocyclic Organic Compound. CAS No. 82302-18-9. Molecular formula: C5H7N5O. Mole weight: 153.14198. Product ID: ACM82302189. Alfa Chemistry ISO 9001:2015 Certified.
6-Amino-4-chloro-1,2-dihydro-1-hydroxy-2-iminopyrimidine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 6-AMINO-4-CHLORO-1,2-DIHYDRO-1-HYDROXY-2-IMINOPYRIMIDINE. Product Category: Heterocyclic Organic Compound. Appearance: White Solid. CAS No. 887352-37-6. Molecular formula: C4H7ClN4O. Mole weight: 160.56. Purity: 0.96. IUPACName: 6-chloro-3-hydroxy-4H-pyrimidine-2,4-diamine. Canonical SMILES: C1=C(N=C(N(C1N)O)N)Cl. Density: 1.93g/cm³. Product ID: ACM887352376. Alfa Chemistry ISO 9001:2015 Certified. Categories: 34960-71-9.
6-Amino-5(2,2-diethoxyethyl)-4-hydroxy pyrimidine
6-Amino-5(2,2-diethoxyethyl)-4-hydroxy pyrimidine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 6-Amino-5-(2,2-diethoxyethyl)-4(3H)-pyrimidinone; 6-Amino-5-(2,2-diethoxyethyl)pyrimidin-4-ol; NSC 59250. Product Category: Heterocyclic Organic Compound. Appearance: White Crystals With a Greenish Cast. CAS No. 7400-6-8. Molecular formula: C10H17N3O3. Mole weight: 227.26. Product ID: ACM7400068. Alfa Chemistry ISO 9001:2015 Certified.
6-Amino-5(2,2-diethoxyethyl)-4-hydroxy Pyrimidine
6-Amino-5(2,2-diethoxyethyl)-4-hydroxy Pyrimidine. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500mg. US Biological Life Sciences.
1-((2R,4aR,7R,8S,8aS)-8-Hydroxy-2-phenylhexahydropyrano[3,2-d][1,3]dioxin-7-yl)pyrimidine-2,4(1H,3H)-dione is a promising therapeutic agent that is yet to gain approval from the FDA. This potential drug candidate has been reported to have beneficial effects in mitigating neurodegenerative disorders like Alzheimer's and Parkinson's disease through efficient amyloid beta and alpha-synuclein proteins aggregation inhibition. Synonyms: 2-(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)-1,5-anhydro-2-deoxy-4,6-O-[(R)-phenylmethylene]-D-altritol. CAS No. 401906-98-7. Molecular formula: C17H18N2O6. Mole weight: 346.33.
2(1H)-Pyrimidinone,3,6-dihydro-6-imino-1-methyl-,hydrochloride(1:1). Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-METHYLCYTOSINE HYDROCHLORIDE;4-Amino-2-hydroxy-3-methylpyrimidine. Product Category: Heterocyclic Organic Compound. CAS No. 90009-77-1. Molecular formula: C5H7N3O.ClH. Mole weight: 161.59. Density: g/cm³. Product ID: ACM90009771. Alfa Chemistry ISO 9001:2015 Certified.
2'-Amino-2'-deoxy-b-D-arabinouridine
2'-Amino-2'-deoxy-b-D-arabinouridine, an effective nucleoside analog employed in the treatment of hematological malignancies such as lymphoma and leukemia, disrupts DNA synthesis, and triggers apoptosis in malignant cells. Furthermore, this compound is currently the subject of research aimed at uncovering its antiviral properties targeting the hepatitis B and C viruses, which causes viral infections that could lead to permanent liver damage. Synonyms: 2'-Amino-2'-deoxy-beta-D-arabinouridine; 2'-Amino-2'-deoxy-β-D-arabinouridine; 1-(2-Amino-2-deoxy-β-D-arabinofuranosyl)-2,4(1H,3H)-pyrimidinedione; 1-(2'-Amino-2'-deoxy-β-D-arabinofuranosyl)uracil; 1-((2R,3S,4S,5R)-3-Amino-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione. Grades: ≥95%. CAS No. 68115-81-1. Molecular formula: C9H13N3O5. Mole weight: 243.22.
2'-Amino-2'-deoxyuridine
2'-Amino-2'-deoxyuridine, a nucleoside analogue, finds its use in chemotherapy as an anti-cancer agent. Its ability to cause DNA damage and trigger apoptosis in cancer cells stem from its selective integration in cancer cell DNA. Additionally, it offers immense potential in the field of oncology research, studying tumor cell differentiation and proliferation. Synonyms: 2'-Amino-2'-deoxy-D-uridine; 2'-deoxy-2'-amino-uridine; 2,4(1H,3H)-pyrimidinedione, 1-(2-amino-2-deoxy-b-D-ribofuranosyl)-; 1-[(2R,3R,4S,5R)-3-amino-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione. Grades: ≥95%. CAS No. 26889-39-4. Molecular formula: C9H13N3O5. Mole weight: 243.22.
2'-Deoxycytidine-5-carboxylic Acid Sodium Salt (>85%)
2'-Deoxycytidine-5-carboxylic Acid Sodium Salt, is derivative of 5-Hydroxy-2'-deoxycytidine, which have been used as a substrate for uracil DNA N-glycosylase and has been used to study the oxidation of DNA due to exposure to reactive oxygen species. Synonyms: 4-Amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-1,2-dihydro-2-oxo-5-pyrimidinecarboxylic Acid Sodium Salt. Grades: 85%. Molecular formula: C10H12N3NaO6. Mole weight: 293.21.
2'-O-Methylcytidine-5'-monophosphate triethylammonium salt
2'-O-methylcytidine 5'-monophosphate is a pyrimidine ribonucleoside 5'-monophosphate that is CMP monomethylated at position O-2'. Synonyms: 2'-O-Methyl-5'-cytidylic acid; ((2R,3R,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-3-hydroxy-4-methoxytetrahydrofuran-2-yl)methyl dihydrogen phosphate; Poly(2'-O-methylcytidylic acid); Poly(rcm). CAS No. 18422-43-0. Molecular formula: C10H16N3O8P. Mole weight: 337.22.
3'-Amino-3'-deoxy-5-methyluridine
3'-Amino-3'-deoxy-5-methyluridine, a pivotal compound widely utilized in the biomedical industry, assumes utmost significance in the investigation of antiviral pharmaceuticals and viral-induced ailments. Synonyms: Uridine, 3'-amino-3'-deoxy-5-methyl-; 1-(3-Amino-3-deoxy-beta-D-ribofuranosyl)thymine; 1-((2R,3R,4S,5S)-4-Amino-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione; 1-((2R,3R,4S,5S)-4-Amino-3-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione. Grades: ≥95%. CAS No. 108630-07-5. Molecular formula: C10H15N3O5. Mole weight: 257.24.
3'-Amino-3'-deoxyuridine
3'-Amino-3'-deoxyuridine, a multifaceted compound extensively utilized in the biomedical sector, assumes a pivotal function in the fabrication of antiviral medications, specifically those combatting DNA viruses such as herpes simplex virus (HSV). Moreover, it serves as a fundamental constituent in the formulation of nucleoside analogs, augmenting their efficacy in combating viral ailments, including cancer. Synonyms: Uridine, 3'-amino-3'-deoxy-; 1-((2R,3R,4S,5S)-4-amino-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione. Grades: ≥95%. CAS No. 70580-90-4. Molecular formula: C9H13N3O5. Mole weight: 243.22.
Used in the preparation of 2-naphthyl substituted diarylpyrimidines (DAPY) analogues. Group: Biochemicals. Alternative Names: 4-[ (4-Hydroxy-2-pyrimidinyl) amino]benzonitrile; 4-[(6-Oxo-1,6-dihydropyrimidin-2-yl)amino]benzonitrile. Grades: Highly Purified. CAS No. 189956-45-4. Pack Sizes: 100mg. US Biological Life Sciences.
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4(3H)-Pyrimidinone,2-amino-5-hydroxy-
4(3H)-Pyrimidinone,2-amino-5-hydroxy-. Uses: Designed for use in research and industrial production. Additional or Alternative Names: NSC95957, MolPort-004-758-959, MolPort-006-673-421, CID262456, 40769-68-4. Product Category: Heterocyclic Organic Compound. CAS No. 40769-68-4. Molecular formula: C4H5N3O2. Mole weight: 127.1014. Purity: 0.96. IUPACName: 2-amino-5-hydroxy-1H-pyrimidin-6-one. Canonical SMILES: C1=C(C(=O)NC(=N1)N)O. Density: 1.84g/cm³. Product ID: ACM40769684. Alfa Chemistry ISO 9001:2015 Certified. Categories: 2-Aminopyrimidine-4,5-diol.
4(3H)-Pyrimidinone,5-amino-6-hydroxy-2-methyl-
4(3H)-Pyrimidinone,5-amino-6-hydroxy-2-methyl-. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-AMINO-4,6-DIHYDROXY-2-METHYLPYRIMIDINE;4(1H)-Pyrimidinone, 5-amino-6-hydroxy-2-methyl- (9CI);5-AMINO-4,6-DIHYDROXY-2-METHYLPYRIMIDINE DIHYDRATE. Product Category: Heterocyclic Organic Compound. CAS No. 98797-08-1. Molecular formula: C5H7N3O2. Mole weight: 141.13. Purity: 0.96. Product ID: ACM98797081. Alfa Chemistry ISO 9001:2015 Certified.
4-amino-1-((2S,3S,4S,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidin-2(1H)-one, a nucleoside analog exhibiting potent antiviral activity against notorious viruses such as HIV and Hepatitis C, inhibits viral replication by getting incorporated into viral RNA and obstructing viral polymerase enzyme, and has emerged as a promising candidate for the development of novel antiviral drugs owing to its unique structure and properties. Synonyms: 4-amino-1-((2S,3S,4S,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2(1H)-ketone. Grades: 98%. Molecular formula: C10H14FN3O4. Mole weight: 259.23.
4-Amino-3-(1-naphthylmethyl)-1H-pyrazolo[3,4-d]pyrimidine-1-(β-D-ribofuranosyl-5'-triphosphate) is a remarkably robust antimetabolite exhibiting significant Inhibition in research of specific malignancies, particularly acute lymphoblastic leukemia. Functioning as an extraordinary competitive inhibitor targeting the intricate processes of DNA and RNA research and development, this exceptional compound profoundly hampers the proliferative propensities of malignant cells. Synonyms: 1-[5-O-[Hydroxy[[hydroxy (phosphonooxy) phosphinyl]oxy]phosphinyl]-b-D-ribofuranosyl]-3- (1-naphthalenylmethyl) -1H-pyrazolo[3, 4-d]pyrimidin-4-amine; 3-(1-NM)-PPTP. CAS No. 476371-81-0. Molecular formula: C21H24N5O13P3. Mole weight: 647.36.
4-Amino-3-(1-naphthylmethyl)-1H-pyrazolo[3,4-D]pyrimidine-1-(β-d-ribofuranosyl-5'-triphosphate). Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1-[5-O-[Hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-3-(1-naphthalenylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine; 3-(1-NM)-PPTP. Product Category: Heterocyclic Organic Compound. CAS No. 476371-81-0. Molecular formula: C21H24N5O13P3. Mole weight: 647.36. Purity: 0.96. IUPACName: [[(2R,3S,4R,5R)-5-[4-amino-3-(naphthalen-1-ylmethyl)pyrazolo[3,4-d]pyrimidin-1-yl]-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate. Canonical SMILES: C1=CC=C2C(=C1)C=CC=C2CC3=NN(C4=C3C(=NC=N4)N)C5C(C(C(O5)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O. Product ID: ACM476371810. Alfa Chemistry ISO 9001:2015 Certified.
4-Amino-6-bromo-5-cyano-7-(2-deoxy-2-fluoro-b-D-arabinofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine is a highly potent biomedical compound, presenting a cutting-edge solution for research of combatting various types of cancer. Its unparalleled inhibitory properties meticulously disrupt the intricate DNA replication machinery within cancer cells, thus impeding their ability to multiply and metastasize. Synonyms: 4-amino-6-bromo-7-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrrolo[2,3-d]pyrimidine-5-carbonitrile; 4-Amino-6-bromo-7-(2-fluoro-2-deoxy-β-D-arabinofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile. Grades: ≥95%. Molecular formula: C12H11BrFN5O3. Mole weight: 372.15.
4-Defluoro Raltegravir
An impurity of Raltegravir. Raltegravir is an integrase inhibitor as an antiretroviral drug. It can be used for the treatment of HIV infection. Synonyms: 1,6-Dihydro-5-hydroxy-1-methyl-2-[1-methyl-1-[[(5-methyl-1,3,4-oxadiazol-2-yl)carbonyl]amino]ethyl]-6-oxo-N-(phenylmethyl)-4-pyrimidinecarboxamide. Grades: > 95%. CAS No. 1193687-87-4. Molecular formula: C20H22N6O5. Mole weight: 426.44.
4-Hydroxy-6-methylpyrimidine
6-Methyl-4-hydroxypyrimidine is used in the preparation of antitumor compounds based upon adenine. Also used in the synthesis of novel purimidine, 3-cyanopyridine and m-amino-N-phenylbenzamide derrivatives as tyrosine kinase inhibitors. Synonyms: 6-Methylpyrimidin-4-ol; 6-Methyl-4(3H)-pyrimidinone; 4-Hydroxy-6-methylpyrimidine; 6-METHYL-4-PYRIMIDINOL; 4-Pyrimidinol,6-methyl; 6-methyl-4(1h)-pyrimidinon; 4-methyl-1H-pyrimidin-6-one. Grades: ≥ 95 %. CAS No. 3524-87-6. Molecular formula: C5H6N2O. Mole weight: 110.11.
4-Hydroxy Pyrimethanil
4-Hydroxy Pyrimethanil is a metabolite of the pesticide Pyrimethanil. Group: Biochemicals. Alternative Names: 2-(4-Hydroxyanilino)-4,6-dimethylpyrimidine; 4-[ (4, 6-Dimethyl-2-pyrimidinyl) amino]phenol. Grades: Highly Purified. CAS No. 81261-84-9. Pack Sizes: 25mg. US Biological Life Sciences.
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4-Hydroxy Pyrimethanil-d4
4-Hydroxy Pyrimethanil is a labeled metabolite of the pesticide Pyrimethanil. Group: Biochemicals. Alternative Names: 2-(4-Hydroxyanilino)-4,6-dimethylpyrimidine-d4; 4-[ (4, 6-Dimethyl-2-pyrimidinyl) amino]phenol-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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5'-Amino-2',5'-dideoxyuridine
5'-Amino-2',5'-dideoxyuridine is an imperative nucleoside analogue of significant relevance in the biomedical sector is effectively harnessed for addressing the ubiquitous viral diseases encompassing herpes and HIV. Distinguished by its remarkable characteristic, this compound effectively obstructs the progression of viral DNA synthesis through its adeptness at terminating replication chains. Moreover, its commendable antiviral attributes render it a promising candidate in the realm of therapeutic agent advancement, effectively countering the virulent onslaught of diverse viral infections. Synonyms: Uridine, 5'-amino-2',5'-dideoxy-; NSC 175992; 1-[(2R,4S,5R)-5-(aminomethyl)-4-hydroxy-tetrahydrofuran-2-yl]pyrimidine-2,4-dione. Grades: ≥95%. CAS No. 35959-38-7. Molecular formula: C9H13N3O4. Mole weight: 227.22.
5-Amino-2'-deoxyuridine hydrochloride
5-Amino-2'-deoxyuridine hydrochloride, an essential component within the biomedical sector, serves as a pivotal precursor for the synthesis of antiviral agents like AZT (zidovudine) - a renowned therapeutic employed in combating the HIV/AIDS epidemic. Noteworthy is its hydrochloride form, augmenting not only solubility but also stability, thereby facilitating the formulation of efficacious medications. Synonyms: 5-Amino-2'-deoxyuridine HCl; 5-Amino-1-((2R,4S,5R)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione hydrochloride; 5-Amino-dU hydrochloride. Grades: ≥95%. CAS No. 73446-40-9. Molecular formula: C9H14ClN3O5. Mole weight: 279.68.
5'-Amino-5'-deoxy-2'-O-methyl-5-methyluridine
5'-Amino-5'-deoxy-2'-O-methyl-5-methyluridine, a biomedical agent employed for the therapeutic management of viral ailments including hepatitis C, showcases remarkable antiviral efficacy a result of its capacity to impede viral replication. Its idiosyncratic chemical constitution enables interference with viral RNA synthesis, effectively arresting the advancement of the infection. Synonyms: 5,2'-O-Dimethyl-5'-amino-5'-deoxyuridine; Uridine, 5'-amino-5'-deoxy-5-methyl-2'-O-methyl-; 1-((2R,3R,4R,5R)-5-Aminomethyl-4-hydroxy-3-methoxy-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione. Grades: ≥95%. CAS No. 251296-69-2. Molecular formula: C11H17N3O5. Mole weight: 271.27.
5-Hydroxymethyl-dC
It is a modified pyrimidine that is capable of producing interstrand cross-links in duplex DNA. It can be analyzed to quantify DNA hydroxymethylation levels in biological samples. Synonyms: 5-Hydroxymethyl-2'-deoxycytidine; hm-Dcmp; 2'-deoxy-5-(hydroxymethyl)cytidine; 5-(Hydroxymethyl)deoxycytidine; 4-Amino-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(hydroxymethyl)pyrimidin-2(1H)-one. Grades: ≥95%. CAS No. 7226-77-9. Molecular formula: C10H15N3O5. Mole weight: 257.24.
6-Amino-2-thiouracil-13C
LAbelled derivative of 6-Amino-2-thiouracil as novel, potent, and selective A3 adenosine receptor antagonists. Group: Biochemicals. Alternative Names: 4-Amino-6-hydroxy-2-mercaptopyrimidine-13C; 4-Amino-2-thioxo-6-pyrimidinone-13C. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
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6-Amino-2-thiouracil-13C2
Derivatives of 6-Amino-2-thiouracil as novel, potent, and selective A3 adenosine receptor antagonists. Group: Biochemicals. Alternative Names: 4-Amino-6-hydroxy-2-mercaptopyrimidine-13C2; 4-Amino-2-thioxo-6-pyrimidinone-13C2; 6-Aminothiouracil-13C2; 6-Amino-2-sulfanyl-4(3H)-pyrimidinone-13C2; 6-Amino-2-mercapto-4-pyrimidinol-13C2. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
6-Amino-2-thiouracil Hydrate
Derivatives of 6-Amino-2-thiouracil as novel, potent, and selective A3 adenosine receptor antagonists. Group: Biochemicals. Alternative Names: 4-Amino-6-hydroxy-2-mercaptopyrimidine Hydrate; 4-Amino-2-thioxo-6-pyrimidinone Monohydrate. Grades: Highly Purified. CAS No. 65802-56-4. Pack Sizes: 2.5g. US Biological Life Sciences.
Worldwide
6-Amino-5-nitroso-2-thiouracil
Pyrimidine with the ability to form complexes with heavy metal ions. Group: Biochemicals. Alternative Names: 6-Amino-2,3-dihydro-5-nitroso-2-thioxo-4(1H)-pyrimidinone; 6-Amino-5-nitroso-2-thio-uracil; 4-Amino-6-hydroxy-2-mercapto-5-nitrosopyrimidine; 6-Amino-5-nitroso-2-thiouracil; NSC 229540. Grades: Highly Purified. CAS No. 1672-48-6. Pack Sizes: 500mg. US Biological Life Sciences.
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6-Amino-5-nitroso-2-thiouracil-13C,15N
Pyrimidine with the ability to form complexes with heavy metal ions. Group: Biochemicals. Alternative Names: 6-Amino-2,3-dihydro-5-nitroso-2-thioxo-4(1H)-pyrimidinone-13C,15N; 6-Amino-5-nitroso-2-thio-uracil-13C,15N; 4-Amino-6-hydroxy-2-mercapto-5-nitrosopyrimidine-13C,15N; 6-Amino-5-nitroso-2-thiouracil-13C,15N; NSC 229540-13C,15N. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
7-Cyano-7-deaza-2'-deoxyguanosine
7-Cyano-7-deaza-2'-deoxyguanosine is a potent antiviral nucleoside analogue commonly used in the biomedical industry for the treatment of viral infections. It demonstrates promising activity against various viruses, including hepatitis B and C. It functions by inhibiting viral replication through targeting viral polymerase enzymes. Synonyms: 2-Amino-7-(2-deoxy-b-D-ribofuranosyl)-5-cyano-7H-pyrrolo[2,3-d]pyrimidin-4(3H)-one; 2'-Deoxytoyocamycin; 2-Amino-7-((2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile. Grades: ≥95%. CAS No. 199859-58-0. Molecular formula: C12H13N5O4. Mole weight: 291.26.
Avanafil Impurity 23
Avanafil Impurity 23. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-hydroxy-4-((4-methoxybenzyl)amino)pyrimidine-5-carboxylic acid. Molecular Formula: C13H13N3O4. Mole Weight: 275.26. Catalog: APB02780.
Avanafil Impurity 37
Avanafil Impurity 37. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-((3-chloro-4-methoxybenzyl)amino)-2-hydroxy-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide. CAS No. 1452128-53-8. Molecular Formula: C18H17ClN6O3. Mole Weight: 400.82. Catalog: APB1452128538.
Avanafil Impurity 38
Avanafil Impurity 38. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-((3-chloro-4-hydroxybenzyl)amino)-2-hydroxy-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide. Molecular Formula: C17H15ClN6O3. Mole Weight: 386.79. Catalog: APB02767.
CUDC-907
CUDC-907 is a dual PI3K and HDAC inhibitor. Studies have shown CUDC-907 is able to enhance antitumor activity when combined with standard of care agents in multiple myeloma and B cell lymphoma xenograft models. Group: Biochemicals. Alternative Names: N-Hydroxy-2-[[[2-(6-methoxy-3-pyridinyl)-4-(4-morpholinyl)thieno[3,2-d]pyrimidin-6-yl]methyl]methylamino]-5-pyrimidinecarboxamide; N-Hydroxy-2-[[[2- (6-methoxypyridin-3-yl) -4- (morpholin-4-yl) thieno[3, 2-d]pyrimidin-6-yl]methyl] (methyl) amino]pyrimidine-5-carboxamide. Grades: Highly Purified. CAS No. 1339928-25-4. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
CUDC-907-d3
CUDC-907-d3. Group: Biochemicals. Alternative Names: N-Hydroxy-2-[[[2-(6-methoxy-3-pyridinyl)-4-(4-morpholinyl)thieno[3,2-d]pyrimidin-6-yl]methyl]methylamino]-5-pyrimidinecarboxamide-d3; N-Hydroxy-2-[[[2- (6-methoxypyridin-3-yl) -4- (morpholin-4-yl) thieno[3, 2-d]pyrimidin-6-yl]methyl] (methyl) amino]pyrimidine-5-carboxamide-d3. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C23H21D3N8O4S, Molecular Weight: 511.57. US Biological Life Sciences.
Worldwide
cyanuric acid amidohydrolase
Along with EC 3.5.1.54 (allophanate hydrolase) and EC 3.5.1.84 (biuret amidohydrolase), this enzyme forms part of the cyanuric-acid metabolism pathway, which degrades s-triazide herbicides, such as atrazine [2-chloro-4-(ethylamino)-6-(isopropylamino)-1,3,5-triazine], in bacteria. This is a key enzyme in the pathway, catalysing the ring cleavage of cyanuric acid. The enzyme is specific for cyanuric acid as substrate as neither the structurally related compounds ammeline (2,4-diamino-6-hydroxy-s-triazine) and ammelide (2-amino-4,6-dihydroxy-s-triazine) nor a number of pyrimidine compounds, such as uracil and cytosine, can act as substrates. Group: Enzymes. Synonyms: AtzD. Enzyme Commission Number: EC 3.5.2.15. CAS No. 132965-78-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4498; cyanuric acid amidohydrolase; EC 3.5.2.15; 132965-78-7; AtzD. Cat No: EXWM-4498.
DL-Leucine
DL-Leucine. Uses: Dl-leucine is a racemic mixture of the d- and l- enantiomers of leucine. dl-leucine is used to form benzimidazole and pyrimidine hydroxy azo dyes with various transition metals. dl-leucine may be used for the evaluation of chiral amino acid separation techniques. dl-leucine is used for the following applications: used as a standard for the measurement of free amino acids used in the process of tritiated leucine uptake used in solution preparation (various organics were used in different combinations and concentrations to model complex surface tension effects, dl-leucine is one of them). it is chosen due to its presence in atmospheric aerosols and ice nucleation activity as well as for its surfactant character. Additional or Alternative Names: (±)-Amino-4-methylpentanoic acid. Product Category: Amino Acids. CAS No. 328-39-2. Molecular formula: (CH3)2CHCH2CH(NH2)CO2H. Mole weight: 131.17. Canonical SMILES: CC(C)CC(N)C(O)=O. ECNumber: 206-328-2. Product ID: ACM328392-1. Alfa Chemistry ISO 9001:2015 Certified.
(D)-(+)-Neopterin
Neopterin, a pyrazino-pyrimidine compound derived from GTP, n is a precursor of tetrahydrobiopterin and can be used as a biochemical marker indicative of cell proliferation. Neopterin is synthesized in response to interferon-γ stimulation, and used as a marker of T helper cell-induced immune activation. Neopterin is also an indicator of oxidative stress, and modulates the effects of reactive oxygen species (ROS). Synonyms: 2-Amino-6-[(1S,2R)-1,2,3-trihydroxypropyl]-4(3H)-pteridinone; Neopterin; 2-Amino-4-hydroxy-6-(1,2,3-trihydroxypropyl)pteridine; 2-Amino-6-((1S,2R)-1,2,3-trihydroxypropyl)-4(8H)-pteridone; 6-D-erythro-Neopterin; D-(+)-Neopterin; D-erythro-Neopterin. Grades: ≥98% by HPLC. CAS No. 2009-64-5. Molecular formula: C9H11N5O4. Mole weight: 253.21.
JNJ 26481585 dihydrochloride
JNJ 26481585 dihydrochloride is a potent and second-generation pan-HDAC inhibitor (IC50 value 0.11 nM for HDAC1, and sub-nanomolar for HDAC2, HDAC4, HDAC10, and HDAC11 in vitro) with antineoplastic activity. JNJ-26481585 inhibiting HDAC leads to continuous acetylation of histone H3, activation of the caspase cascade, upregulation of p21, and tumor cell apoptosis. Uses: Antitumor agent. Synonyms: JNJ 26481585 dihydrochloride; JNJ26481585 dihydrochloride; JNJ-26481585 dihydrochloride; Quisinostat HCl; N-hydroxy-2-(4-((((1-methyl-1H-indol-3-yl)methyl)amino)methyl)piperidin-1-yl)pyrimidine-5-carboxamide dihydrochloride. Grades: 99%. CAS No. 875320-31-3. Molecular formula: C21H26N6O2.2HCl. Mole weight: 467.39.
Lck inhibitor 2
Lck inhibitor 2 is a bis-anilinopyrimidine inhibitor of tyrosine kinases including LCK, BTK, LYN, SYK, and TXK. It inhibited 48 kinases with control less than 1%(33 of them tyrosine kinases, almost half of the 71 tyrosine kinases in the panel). Synonyms: Benzamide, 3-[[4-[(5-hydroxy-2-methylphenyl)amino]-2-pyrimidinyl]amino]-. Grades: >98%. CAS No. 944795-06-6. Molecular formula: C18H17N5O2. Mole weight: 335.36.
Lopinavir
A selective HIV protease inhibitor. An analogue of Ritonavir. Group: Biochemicals. Alternative Names: (α S) -N-[ (1S, 3S, 4S) -4-[[2- (2, 6-DIMETHYLPHENOXY) ACETYL]AMINO]-3-HYDROXY-5-PHENYL-1- (PHENYLMETHYL) PENTYL]TETRAHYDRO-α - (1-METHYLETHYL) -2-OXO-1 (2H) -PYRIMIDINEACETAMIDE; A 157378.0; ABT 378; ALUVIRAN; KOLETRA. Grades: Highly Purified. CAS No. 192725-17-0. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Lopinavir Impurity R
Lopinavir Impurity R is an impurity of Lopinavir, a selective HIV protease inhibitor. Synonyms: (αS)-3-[2-(2,6-Dimethylphenoxy)acetyl]-N-[(1S,3S,4S)-4-[[2-(2,6-dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-α-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetamide. Grades: > 95%. CAS No. 943250-66-6. Molecular formula: C47H58N4O7. Mole weight: 790.99.
Lopinavir Metabolite M-1
A major metabolite of Lopinavir. Group: Biochemicals. Alternative Names: (α S) -N-[ (1S, 3S, 4S) -4-[[ (2, 6-Dimethylphenoxy) acetyl]amino]-3-hydroxy-5-phenyl-1- (phenylmethyl) pentyl]tetrahydro-α - (1-methylethyl) -2, 4-dioxo-1 (2H) -pyrimidineacetami-de. Grades: Highly Purified. CAS No. 192725-39-6. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Lopinavir Metabolite M-1
Lopinavir Metabolite M-1 is a major metabolite of Lopinavir. Synonyms: (αS)-N-[(1S,3S,4S)-4-[[(2,6-Dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-α-(1-methylethyl)-2,4-dioxo-1(2H)-pyrimidineacetami- de; 4-Oxo Lopinavir. Grades: > 95%. CAS No. 192725-39-6. Molecular formula: C37H46N4O6. Mole weight: 642.78.
Lopinavir Metabolite M-3/M-4
A major metabolite of Lopinavir. Group: Biochemicals. Alternative Names: (α S) -N-[ (1S, 3S, 4S) -4-[[ (2, 6-Dimethylphenoxy) acetyl]amino]-3-hydroxy-5-phenyl-1- (phenylmethyl) pentyl]tetrahydro-4-hydroxy-α - (1-methylethyl) -2-oxo-1 (2H) -pyrimidine-acetamide. Grades: Highly Purified. CAS No. 357275-54-8. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Lopinavir Metabolite M-3/M-4
Lopinavir Metabolite M-3/M-4 is an impurity of Lopinavir, a selective HIV protease inhibitor. Synonyms: 1(2H)-Pyrimidineacetamide, N-[(1S,3S,4S)-4-[[2-(2,6-dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-4-hydroxy-α-(1-methylethyl)-2-oxo-, (αS)-; (αS)-N-[(1S,3S,4S)-4-[[2-(2,6-Dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-4-hydroxy-α-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetamide; 1(2H)-Pyrimidineacetamide, N-[(1S,3S,4S)-4-[[(2,6-dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-4-hydroxy-α-(1-methylethyl)-2-oxo-, (αS)-; DES(2-oxo-tetrahydropyrimidinyl)-2-oxo-4-hydroxy-tetrahydropyrimidinyl lopinavir. Grades: ≥95%. CAS No. 357275-54-8. Molecular formula: C37H48N4O6. Mole weight: 644.80.
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