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| Product | Description | |
|---|---|---|
| aminoglycoside 2''-phosphotransferase | Requires Mg2+. This bacterial enzyme phosphorylates many 4,6-disubstituted aminoglycoside antibiotics that have a hydroxyl group at position 2'', including kanamycin A, kanamycin B, tobramycin, dibekacin, arbekacin, amikacin, gentamicin C, sisomicin and netilmicin. In most, but not all, cases the phosphorylation confers resistance against the antibiotic. Some forms of the enzyme use ATP as a phosphate donor in appreciable amount. The enzyme is often found as a bifunctional enzyme that also catalyses 6'-aminoglycoside N-acetyltransferase activity. The bifunctional enzyme is the most clinically important aminoglycoside-modifying enzyme in Gram-positive bacteria, responsible for high-level resistance in both Enterococci and Staphylococci. Group: Enzymes. Synonyms: aphD (gene name); APH(2''); aminoglycoside (2'') kinase; gentamicin kinase (ambiguous); gentamicin phosphotransferase (ambiguous). Enzyme Commission Number: EC 2.7.1.190. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3023; aminoglycoside 2''-phosphotransferase; EC 2.7.1.190; aphD (gene name); APH(2''); aminoglycoside (2'') kinase; gentamicin kinase (ambiguous); gentamicin phosphotransferase (ambiguous). Cat No: EXWM-3023. |  |
| aminoglycoside 3-N-acetyltransferase | Different from EC 2.3.1.60 gentamicin 3-N-acetyltransferase. A wide range of antibiotics containing the 2-deoxystreptamine ring can act as acceptors, including gentamicin, kanamycin, tobramycin, neomycin and apramycin. Group: Enzymes. Synonyms: 3-aminoglycoside acetyltransferase; 3-N-aminoglycoside acetyltransferase; aminoglycoside N3-acetyltransferase; acetyl-CoA:2-deoxystreptamine-antibiotic N3'-acetyltransferase (incorrect); aminoglycoside N3'-acetyltransferase (incorrect). Enzyme Commission Number: EC 2.3.1.81. CAS No. 60120-42-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2262; aminoglycoside 3-N-acetyltransferase; EC 2.3.1.81; 60120-42-5; 3-aminoglycoside acetyltransferase; 3-N-aminoglycoside acetyltransferase; aminoglycoside N3-acetyltransferase; acetyl-CoA:2-deoxystreptamine-antibiotic N3'-acetyltransferase (incorrect); aminoglycoside N3'-acetyltransferase (incorrect). Cat No: EXWM-2262. | |
| aminoglycoside 6'-N-acetyltransferase | The antibiotics kanamycin A, kanamycin B, neomycin, gentamicin C1a, gentamicin C2 and sisomicin are substrates. The antibiotic tobramycin, but not paromomycin, can also act as acceptor. The 6-amino group of the purpurosamine ring is acetylated. Group: Enzymes. Synonyms: aminoglycoside N6'-acetyltransferase; aminoglycoside-6'-acetyltransferase; aminoglycoside-6-N-acetyltransferase; kanamycin acetyltransferase. Enzyme Commission Number: EC 2.3.1.82. CAS No. 56467-65-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2263; aminoglycoside 6'-N-acetyltransferase; EC 2.3.1.82; 56467-65-3; aminoglycoside N6'-acetyltransferase; aminoglycoside-6'-acetyltransferase; aminoglycoside-6-N-acetyltransferase; kanamycin acetyltransferase. Cat No: EXWM-2263. | |
| 1,2,4,6-Tetra-O-acetyl-3-deoxy-3-N-(4-nitrobenzamido)-D-galactopyranose | 1,2,4,6-Tetra-O-acetyl-3-deoxy-3-N-(4-nitrobenzamido)-D-galactopyranose, identified as a chemical entity of paramount significance, assumes a critical role in augmenting the development of antibiotics as an efficacious remedy to counter bacterial infections. With a proclivity for serving as a precursor for the synthesis of aminoglycoside antibiotics, such as kanamycin and amikacin, it exhibits promise in the race for combating pernicious bacteria and thwarting their detrimental effects on the human body. Synonyms: (3R,4S,5R,6R)-6-(Acetoxymethyl)-4-(4-nitrobenzamido)tetrahydro-2H-pyran-2,3,5-triyl triacetate; 947590-43-4. CAS No. 947590-43-4. Molecular formula: C21H24N2O12. Mole weight: 496.42. |  |
| 16S rRNA (adenine1408-N1)-methyltransferase | The enzyme provides a panaminoglycoside-resistant nature through interference with the binding of aminoglycosides toward the A site of 16S rRNA through N1-methylation at position adenine1408. Group: Enzymes. Synonyms: kanamycin-apramycin resistance methylase; 16S rRNA:m1A1408 methyltransferase; KamB; NpmA; 16S rRNA m1A1408 methyltransferase. Enzyme Commission Number: EC 2.1.1.180. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1779; 16S rRNA (adenine1408-N1)-methyltransferase; EC 2.1.1.180; kanamycin-apramycin resistance methylase; 16S rRNA:m1A1408 methyltransferase; KamB; NpmA; 16S rRNA m1A1408 methyltransferase. Cat No: EXWM-1779. | |
| 16S rRNA (guanine1405-N7)-methyltransferase | The enzyme from the antibiotic-producing bacterium Micromonospora zionensis specifically methylates guanine1405 at N7 in 16S rRNA, thereby rendering the ribosome resistant to 4,6-disubstituted deoxystreptamine aminoglycosides, which include gentamicins and kanamycins. Group: Enzymes. Synonyms: methyltransferase Sgm; m7G1405 Mtase; Sgm Mtase; Sgm; sisomicin-gentamicin methyltransferase; sisomicin-gentamicin methylase; GrmA; RmtB; RmtC; ArmA. Enzyme Commission Number: EC 2.1.1.179. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1777; 16S rRNA (guanine1405-N7)-methyltransferase; EC 2.1.1.179; methyltransferase Sgm; m7G1405 Mtase; Sgm Mtase; Sgm; sisomicin-gentamicin methyltransferase; sisomicin-gentamicin methylase; GrmA; RmtB; RmtC; ArmA. Cat No: EXWM-1777. | |
| 1-Deamino-1-hydroxysagamicin | 1-Deamino-1-hydroxysagamicin is an aminoglycoside antibiotic produced by micromonospora sagarmiensis SU-2 (KY11509). It has anti-gram-positive and negative bacteria activity. Synonyms: SU-3. CAS No. 72614-86-9. Molecular formula: C20H40N4O8. Mole weight: 464.55. | |
| 1L-Epi-2-inosose | 1L-Epi-2-inosose is a vital intermediate in the pharmaceutical industry. It is notably used in the synthesis of Trobamicin and various aminoglycoside antibiotics. These antibiotics are primarily utilized for treating severe bacterial infections resistant to other antibiotics. Synonyms: (2S,3S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexan-1-one; (2R,3S,4S,5S,6S)-2,3,4,5,6-pentahydroxycyclohexanone; D-epi-4-Inosose; L-epi-2-Inosose; Racemic epi-inosose;(2RS,3SR,5SR,6SR)-epi-inosose; 2L-2,3,4,6/5-Pentahydroxycyclohexanone; 1L-epi-2-Inosose, >=98.0% (HPLC);(2R,3S,5S,6S)-2,3,4,5,6-pentahydroxycyclohexan-1-one. CAS No. 33471-33-9. Molecular formula: C6H10O6. Mole weight: 178.14. | |
| 1-N-Ethylgaramine Sulfate | 1-N-Ethylgaramine sulfate is a derivative of Garamine (triacetate salt: G245300), an impurity of Gentamicin (G360600). Gentamicin is a widely used aminoglycoside antibiotic that is toxic to the kidney and the inner ear. Group: Biochemicals. Grades: Highly Purified. CAS No. 864371-49-3. Pack Sizes: 5mg, 50mg. Molecular Formula: C15H31N3O6 xH2SO4. US Biological Life Sciences. |  Worldwide |
| 2,5-Dibromopentanoic Acid | 2,5-Dibromopentanoic Acid is used in the synthesis of inhibitors for aminoglycoside resistant bacteria. Also used in the preparation of sequence specific base pair mimics as topoisomerase IB inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 1450-81-3. Pack Sizes: 250mg, 2.5g. Molecular Formula: C5H8Br2O2. US Biological Life Sciences. | Worldwide |
| 2-Acetamido-2,6-dideoxy-D-galactose | 2-Acetamido-2,6-dideoxy-D-galactose, an essential constituent in the production of diverse breeds of antimicrobials, embraces macrolides and aminoglycosides. Nevertheless, it also performs a crucial role as an antagonist of N-acetylglucosamine transferase, a pivotal enzyme that facilitates the synthesis of intricate glycoproteins. Moreover, scientific scrutiny has demonstrated that 2-Acetamido-2,6-dideoxy-D-galactose exhibits promising prospects in the treatment of specified bacterial infections and malignant neoplastic diseases. Synonyms: N-Acetyl-D-fucosamine. Molecular formula: C8H15NO5. Mole weight: 205.21. | |
| 2'''-acetyl-6'''-hydroxyneomycin C deacetylase | Involved in the biosynthetic pathway of aminoglycoside antibiotics of the neomycin family. The enzyme from the bacterium Streptomyces fradiae also catalyses EC 3.5.1.112, 2'-N-acetylparomamine deacetylase. Group: Enzymes. Synonyms: neoL (gene name). Enzyme Commission Number: EC 3.5.1.113. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4393; 2'''-acetyl-6'''-hydroxyneomycin C deacetylase; EC 3.5.1.113; neoL (gene name). Cat No: EXWM-4393. | |
| 2-Deoxy-4-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl]-6-O-(2,6-diamino-2,6-dideoxy-α-D-gluco-hexopyranosyl)-L-streptamine | Gentamicin EP impurity D is an impurity of Gentamicin which is an aminoglycoside antibiotic. Synonyms: Gentamicin EP Impurity D. Molecular formula: C19H39N5O9. Mole weight: 481.54. | |
| 2-deoxy-scyllo-inosamine dehydrogenase (AdoMet-dependent) | Involved in the biosynthetic pathway of the aminoglycoside antibiotics of the butirosin family. The enzyme from Bacillus circulans was shown to be a radical S-adenosyl-L-methionine (SAM) enzyme. cf. EC 1.1.1.329, 2-deoxy-scyllo-inosamine dehydrogenase. Group: Enzymes. Synonyms: btrN (gene name); 2-deoxy-scyllo-inosamine dehydrogenase (SAM-dependent). Enzyme Commission Number: EC 1.1.99.38. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0466; 2-deoxy-scyllo-inosamine dehydrogenase (AdoMet-dependent); EC 1.1.99.38; btrN (gene name); 2-deoxy-scyllo-inosamine dehydrogenase (SAM-dependent). Cat No: EXWM-0466. | |
| 2-Hydroxygentamicin A3 | 2-Hydroxygentamicin A3 is a 3 aminoglycoside antibiotic produced by Micromonospora purpurea. It has anti-gram-positive and negative bacteria activity. CAS No. 78874-52-9. Molecular formula: C18H36N4O11. Mole weight: 484.50. | |
| 2-Hydroxygentamicin B | 2-Hydroxygentamicin B is a 3 aminoglycoside antibiotic produced by Micromonospora purpurea. It has anti-gram-positive and negative bacteria activity. CAS No. 78874-50-7. Molecular formula: C19H38N4O11. Mole weight: 498.52. | |
| 2-Hydroxygentamicin B1 | 2-Hydroxygentamicin B1 is a 3 aminoglycoside antibiotic produced by Micromonospora purpurea. It has anti-gram-positive and negative bacteria activity. CAS No. 78874-51-8. Molecular formula: C20H40N4O11. Mole weight: 512.55. | |
| 2-Hydroxy JI-20 A | 2-Hydroxy JI-20 A is an aminoglycoside antibiotic produced by Micromonospora purpurea. It has anti-gram-positive and negative bacteria activity. Molecular formula: C19H39N5O10. Mole weight: 497.55. | |
| 2-Hydroxy JI-20 B | 2-Hydroxy JI-20 B is an aminoglycoside antibiotic produced by Micromonospora purpurea. It has anti-gram-positive and negative bacteria activity. Molecular formula: C20H41N5O10. Mole weight: 511.57. | |
| 3-Amino-3-cyano-azetidine-1-carboxylic Acid tert-Butyl Ester | 3-Amino-3-cyano-azetidine-1-carboxylic Acid tert-Butyl Ester can be synthesized from 1-Boc-3-azetidinone (B624560), a compound used for the preparation of antibacterial aminoglycoside analogs. Group: Biochemicals. Grades: Highly Purified. CAS No. 1254120-12-1. Pack Sizes: 5mg, 10mg. Molecular Formula: C9H15N3O2, Molecular Weight: 197.23. US Biological Life Sciences. | Worldwide |
| 3''-N-demethyl gentamicin C1a | 3''-N-demethyl gentamicin C1a is an aminoglycoside antibiotic produced by Micromonospora sagamiensis G-665. CAS No. 59864-29-8. Molecular formula: C18H37N5O7. Mole weight: 435.52. | |
| 3-O-Demethyl-2'-N-glylfortimicin B | 3-O-Demethyl-2'-N-glylfortimicin B is an aminoglycoside antibiotic produced by Micromonospora olvoasterospora MK-70, MK-80 and Mm 744. CAS No. 71640-65-8. Molecular formula: C16H33N5O6. Mole weight: 391.46. | |
| 3-O-Demethylfortimicin A | 3-O-Demethylfortimicin A is an aminoglycoside antibiotic produced by Micromonospora olvoasterospora MK-70 and Mm 744. It has anti-gram-positive and negative bacteria activity. Synonyms: A 49759. CAS No. 74842-47-0. Molecular formula: C16H33N5O6. Mole weight: 391.46. | |
| 3-O-Demethylfortimicin KE | 3-O-Demethylfortimicin KE is an aminoglycoside antibiotic produced by Micromonospora olvoasterospora MK-70, MK-80 and Mm 744. CAS No. 74667-48-4. Molecular formula: C13H28N4O5. Mole weight: 320.38. | |
| 4''-α-D-Glucopyranosylkanamycin B | It is produced by the strain of Streptomyces kanamyceticus A-4-6. It's an aminoglycoside antibiotic. It has anti-gram positive bacteria and negative bacteria activity. Synonyms: 4''-alpha-D-Glucopyranosylkanamycin B; D-Streptamine, O-2,6-diamino-2,6-dideoxy-alpha-D-glucopyranosyl-(1-4)-O-(O-alpha-D-glucopyranosyl-(1-4)-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1-6)-2-deoxy-; 4,6-Diamino-3-[(3-amino-3-deoxy-4-O-hexopyranosylhexopyranosyl)oxy]-2-hydroxycyclohexyl 2,6-diamino-2,6-dideoxyhexopyranoside. Grades: 95%. CAS No. 84123-75-1. Molecular formula: C24H47N5O15. Mole weight: 645.65. | |
| 4-(γ-L-glutamylamino)butanoyl-[BtrI acyl-carrier protein] monooxygenase | Catalyses a step in the biosynthesis of the side chain of the aminoglycoside antibiotics of the butirosin family. FMNH2 is used as a free cofactor. Forms a complex with a dedicated NAD(P)H:FMN oxidoreductase. The enzyme is not able to hydroxylate free substrates, activation by the acyl-carrier protein is mandatory.Octanoyl-S-[BtrI acyl-carrier protein] is also accepted. Group: Enzymes. Synonyms: btrO (gene name). Enzyme Commission Number: EC 1.14.14.13. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0910; 4-(γ-L-glutamylamino)butanoyl-[BtrI acyl-carrier protein] monooxygenase; EC 1.14.14.13; btrO (gene name). Cat No: EXWM-0910. | |
| 5-Bromopentanoic acid | 5-Bromopentanoic acid can be used for the synthesis of inhibitors for aminoglycoside resistant bacteria [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2067-33-6. Pack Sizes: 1 mg. Product ID: HY-W016456. |  |
| 5-[N-(HABA-Cbz)] 3,6'-Di(N-benzyloxycarbonyl) Kanamycin A | 5-[N-(HABA-Cbz)] 3,6'-Di(N-benzyloxycarbonyl) Kanamycin A is an impurity of Amikacin, an semisynthetic aminoglycoside antibotic derived from Kanamycin A. Molecular formula: C46H61N5O19. Mole weight: 988. | |
| 6-Carboxytetramethylrhodamine succinimidyl ester | 6-Carboxytetramethylrhodamine succinimidyl ester is a fluorescent probe used for labeling peptides and aminoglycoside antibiotics post chemical modification. This probe also has been used in automated DNA and nucleic acid sequencing by capillary electrophoresis. Synonyms: 6-TAMRA SE; 6-TAMRA N-succinimidyl ester; 6-Carboxy-tetramethylrhodamine N-succinimidyl ester. CAS No. 150810-69-8. Molecular formula: C29H25N3O7. Mole weight: 527.53. | |
| 6'''-Deamino-6'''-hydroxyneomycin B dihydrate | 6'''-Deamino-6'''-hydroxyneomycin B dihydrate is an aminoglycoside antibiotic produced by Streptomyces fradiae UC 75. It has anti-gram-positive and negative bacteria activity. Synonyms: 6'''-Deamino-6'''-hydroxyneomycin B; D-Streptamine, O-2-amino-2-deoxy-beta-L-idopyranosyl-(1-3)-O-beta-D-ribofuranosyl-(1-5)-O-(2,6-diamino-2,6-dideoxy-alpha-D-glucopyranosyl-(1-4))-2-deoxy-, (R-(E))-; D-Streptamine, O-2-amino-2-deoxy-beta-L-idopyranosyl-(1-3)-O-beta-D-ribofuranosyl-(1-5)-O-(2,6-diamino-2,6-dideoxy-alpha-D-glucopyranosyl-(1-4)-2-deoxy-, dihydrate. CAS No. 78524-73-9. Molecular formula: C23H45N5O14. Mole weight: 615.63. | |
| 6'''-Deamino-6'''-hydroxyneomycin C | 6'''-Deamino-6'''-hydroxyneomycin C is an aminoglycoside antibiotic produced by Streptomyces fradiae UC 75. It has anti-gram-positive and negative bacteria activity. Synonyms: 6'''-hydroxyneomycin C; Neomycin Y2; (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2-amino-2-deoxy-alpha-D-glucopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranoside. Molecular formula: C23H45N5O14. Mole weight: 615.63. | |
| 6'''-Deamino-6'''-hydroxyparomomycin | 6'''-Deamino-6'''-hydroxyparomomycin is an aminoglycoside antibiotic produced by Streptomyces rimosus forma paromomycinus A67M15. It has anti-gram-positive and negative bacteria activity. Synonyms: 6'''-Hydroxyparmomomycin; 6'''-Deamino-6'''-hydroxyparomomycin I. CAS No. 78524-72-8. Molecular formula: C23H44N4O15. Mole weight: 616.61. | |
| 6'''-Deamino-6'''-hydroxyparomomycin II | 6'''-Deamino-6'''-hydroxyparomomycin II is an aminoglycoside compound produced by Streptomyces rimosus forma paromomycinus A67M15. Synonyms: 5'''-Epi-6'''-deamino-6'''-hydroxyparomomycin. Molecular formula: C23H44N4O15. Mole weight: 616.61. | |
| 6'''-hydroxyneomycin C oxidase | Contains FAD. Involved in the biosynthetic pathway of aminoglycoside antibiotics of the neomycin family. Works in combination with EC 2.6.1.95, neomycin C transaminase, to replace the 6'''-hydroxy group of 6'''-hydroxyneomycin C with an amino group.Also catalyses EC 1.1.3.43, paromamine 6'-oxidase. Group: Enzymes. Synonyms: neoG (gene name); neoQ (obsolete gene name). Enzyme Commission Number: EC 1.1.3.44. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0417; 6'''-hydroxyneomycin C oxidase; EC 1.1.3.44; neoG (gene name); neoQ (obsolete gene name). Cat No: EXWM-0417. | |
| 6''-O-Carbamoyltobramycin | 6''-O-Carbamoyltobramycin is an aminoglycoside antibiotic produced by Streptomyces tenebrarius. 6''-O-Carbamoyltobramycin has a broad antibacterial spectrum and has a strong effect on Gram-positive and negative bacteria and mycobacteria. Synonyms: Nebramycin V'; Nebramycin factor 5'; Nebramycin-5'; 6-O-Carbamoyltob; (1S,2S,3R,4S,6R)-4,6-diamino-3-[(2,6-diamino-2,3,6-trideoxy-alpha-D-ribo-hexopyranosyl)oxy]-2-hydroxycyclohexyl 3-amino-6-O-carbamoyl-3-deoxy-alpha-D-glucopyranoside. Grades: >96%. CAS No. 51736-77-7. Molecular formula: C19H38N6O10. Mole weight: 510.54. | |
| Amikacin disulfate | Amikacin disulfate (BAY 41-6551 dissulfate) is an aminoglycoside antibiotic and a semisynthetic analog of kanamycin. Amikacin disulfate is bactericidal, acting directly on the 30S and 50S bacerial ribosomal subunits to inhibit protein synthesis. Amikacin disulfate is very active against most Gram-negative bacteria including gentamicin - and tobramycin-resistant strains. Amikacin disulfate also inhibits the infections caused by susceptible Nocardia and nontuberculous mycobacteria [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 41-6551 disulfate. CAS No. 39831-55-5. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0509B. | |
| Amikacin hydrate | Amikacin hydrate (BAY 41-6551 hydrate) is an aminoglycoside antibiotic and a semisynthetic analog of kanamycin. Amikacin hydrate is bactericidal, acting directly on the 30S and 50S bacerial ribosomal subunits to inhibit protein synthesis. Amikacin hydrate is very active against most Gram-negative bacteria including gentamicin - and tobramycin-resistant strains. Amikacin hydrate also inhibits the infections caused by susceptible Nocardia and nontuberculous mycobacteria [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 41-6551 hydrate. CAS No. 1257517-67-1. Pack Sizes: 50 mg; 100 mg; 500 mg. Product ID: HY-B0509. | |
| Amikacin hydrate | Amikacin hydrate is an aminoglycoside antibiotic and a semisynthetic analog of kanamycin. Amikacin works by binding to the bacterial 30S ribosomal subunit, causing misreading of mRNA and leaving the bacterium unable to synthesize proteins vital to its growth. Synonyms: BAY 41-6551 hydrate. Grades: >98%. CAS No. 1257517-67-1. Molecular formula: C22H45N5O14. Mole weight: 603.62. | |
| Amikacin sulfate | Amikacin sulfate (BAY 41-6551 sulfate) is an aminoglycoside antibiotic and a semisynthetic analog of kanamycin. Amikacin sulfate is bactericidal, acting directly on the 30S and 50S bacerial ribosomal subunits to inhibit protein synthesis. Amikacin sulfate is very active against most Gram-negative bacteria including gentamicin - and tobramycin-resistant strains. Amikacin sulfate also inhibits the infections caused by susceptible Nocardia and nontuberculous mycobacteria [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 41-6551 sulfate. CAS No. 149022-22-0. Pack Sizes: 50 mg; 100 mg. Product ID: HY-107813. | |
| AMIKACIN SULFATE | Amikacin disulfate is an aminoglycoside sulfate salt obtained by combining amikacin with two molar equivalents of sulfuric acid. It has a role as an antibacterial drug, an antimicrobial agent and a nephrotoxin. It contains an amikacin(4+). CAS No. 39831-55-5. Product ID: PAP-0040. Molecular formula: C22H45N5O17S. Category: Antibacterial, anti-inflammatory and antiviral. Product Keywords: Antibacterial, Anti-inflammatory and Antiviral Series; AMIKACIN SULFATE; PAP-0040; Antibacterial, anti-inflammatory and antiviral; C22H45N5O17S; 39831-55-5. Standard: EP/ USP/ CP. Color: white to off-white. EC Number: 254-648-6. Physical State: solid. Solubility: H2O: soluble50mg/mL. Storage: Inert atmosphere,2-8°C. Applications: Amikacin sulfate is a semi-synthetic aminoglycoside antibiotic, the antibacterial spectrum is similar to gentamicin, and it is effective against Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli and Proteus. Product Description: Amikacin sulfate is a semi-synthetic aminoglycoside antibiotic, the antibacterial spectrum is similar to gentamicin, and it is effective against Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli and Proteus. |  |
| Amikacin Sulfate Multivesicular Liposome | Amikacin sulfate is an aminoglycoside that inhibits protein synthesis by binding tightly to the A site of 30S ribosomal 16SrRNA. This product is a pre-formulated liposome with amikacin sulfate. It is only for research purposes and for the injection to laboratory animals. Group: Drug-loaded liposome. Categories: liposomes, niosomes, ethosomes, and transfersomes. |  |
| Antibiotic 477-2h | It is an aminoglycoside antibiotic produced by the strain of Micromonospora sagamiensis G-477. It has weak activity against gram-positive and gram-negative bacteria. Synonyms: 477-2H. CAS No. 72751-74-7. Molecular formula: C24H46N4O15. Mole weight: 630.64. | |
| Antibiotic 66-40C | It is a dimeric aminoglycoside antibiotic produced by the strain of Micromonospora inyoensis. Synonyms: beta-L-Arabinopyranoside, 2, 7, 14, 19-tetraamino-2, 3, 4, 4a, 7, 8, 12a, 13, 14, 15, 16, 16a, 18, 19, 20, 24a-hexadecahydro-4, 16-dihydroxy-6, 10:18, 22-diepoxy-1H, 6H-dibenzo(b, l)(1, 11, 4, 14)dioxadiazacycloeicosine-3, 15-diylbis(3-deoxy-4-C-methyl-3-(methylamino)-, (2R-(2R*, 3S*, 4R*, 4aR*, 6S*, 7R*, 12aS*, 14R*, 15S*, 16R*, 16aR*, 18S*, 19R*, 24aS*))-; Aminoglycoside 66-40-C. CAS No. 60870-21-5. Molecular formula: C38H64N8O14. Mole weight: 856.96. | |
| Antibiotic JI 20A | Antibiotic JI 20A is an aminoglycoside antibiotic originally isolated from Micromonospora purpurea. Synonyms: JI-20 A; BRN 1668513; 4,6-diamino-3-{[3-deoxy-4-C-methyl-3-(methylamino)pentopyranosyl]oxy}-2-hydroxycyclohexyl 2,6-diamino-2,6-dideoxyhexopyranoside. CAS No. 51846-97-0. Molecular formula: C19H39N5O9. Mole weight: 481.54. | |
| Anti-Infection Compound Library | A unique collection of 2977 anti-infective compounds including anti-bacterial, anti-fungi, anti-Human Cytomegalovirus (HCMV), anti-HIV, anti-SARS, anti-influenza, etc; - Effective tool for new anti-infective drugs high throughput screening and high content screening, containing sulfonamides, tetracyclines, aminoglycosides, and macrolide derivatives, etc. - Bioactivity and safety confirmed by clinical research and trials; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L1800. Categories: Anti-Infection Compounds Libraries. |  |
| Apramycin | Apramycin is an aminoglycoside antibiotic produced by Streptomyces tenebrarius. Apramycin has a broad antibacterial spectrum and has a strong effect on both Gram-positive and negative bacteria. Uses: Anti-bacterial agents. Synonyms: Nebramycin II; Nebramycin factor 2; Apramycinum; Apramicina. Grades: >98%. CAS No. 37321-09-8. Molecular formula: C21H41N5O11. Mole weight: 539.58. | |
| Apramycin sulfate | Apramycin (EBL 1003) sulfate is an orally active, acidic pH tolerant and aminoglycoside-modifying-enzymes-tolerant aminoglycoside antibiotic which inhibits protein biosynthesis by targeting the bacterial ribosome. Apramycin sulfate is a potential anti-drug-resistance antibiotic [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Nebramycin II sulfate. CAS No. 65710-07-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-B1329. | |
| Apramycin Sulfate | Apramycin is an aminoglycoside antibiotic produced by Streptomyces. It has activity against Gram-negative bacteria. It acts by blocking translocation and binding to the eukaryotic decoding site despite differences in key residues required for apramycin recognition by the bacterial target. Uses: Anti-bacterial agents. Synonyms: FEMA 2131; FEMA2131; FEMA-2131. Grades: >98%. CAS No. 65710-07-8. Molecular formula: C21H43N5O15S. Mole weight: 637.66. | |
| Arbekacin | Arbekacin(INN) is a semisynthetic aminoglycoside antibiotic. It is primarily used for the treatment of infections caused by multi-resistant bacteria including methicillin-resistant Staphylococcus aureus(MRSA). Grades: >98%. CAS No. 51025-85-5. Molecular formula: C22H44N6O10. Mole weight: 552.31. | |
| Arbekacin sulfate | Arbekacin is a semi-synthetic aminoglycoside antibiotic used to treat infections caused by methicillin-resistant Staphylococcus aureus (MRSA). Synonyms: Habekacin. CAS No. 104931-87-5. Molecular formula: C22H46N6O14S. Mole weight: 650.70. | |
| Ashimycin A | Ashimycin A is an aminoglycoside antibiotic produced by Streptomyces griseus FT3-4. It has a broad-spectrum antibacterial activity, but is lower than streptomycin. Synonyms: 2,4-Dicarbamimidamido-3,5,6-trihydroxycyclohexyl 2-C-carboxypentofuranosyl-(1->4)-2-deoxy-2-(methylamino)hexopyranosyl-(1->2)-5-deoxy-3-C-formylpentofuranoside. CAS No. 123482-11-1. Molecular formula: C27H47N7O18. Mole weight: 757.70. | |
| Ashimycin B | Ashimycin B is an aminoglycoside antibiotic produced by Streptomyces griseus FT3-4. It has a broad-spectrum antibacterial activity, but is lower than streptomycin. Synonyms: D-Streptamine, O-2-deoxy-2-((hydroxyacetyl)methylamino)-alpha-L-glucopyranosyl-(1-2)-O-5-deoxy-3-C-formyl-alpha-L-lyxofuranosyl-(1-4)-N,N'-bis(aminoiminomethyl)-. CAS No. 123482-12-2. Molecular formula: C23H41N7O14. Mole weight: 639.61. | |
| BB-K 6 N-(Benzyloxy) Carbamate | BB-K 6 N-(Benzyloxy) Carbamate is an intermediate in the synthesis of BB-K 6, a semi-synthetic aminoglycoside antibiotic derived from Kanamycin A. Molecular formula: C30H49N5O15. Mole weight: 719.73. | |
| BB-K 6 Sulfate Salt | BB-K 6 is a semi-synthetic aminoglycoside antibiotic derived from Kanamycin A. Synonyms: (S)-O-3-Amino-3-deoxy-α-D-glucopyranosyl-(1?6)-O-[6-[(4-amino-2-hydroxy-1-oxobutyl)amino]-6-deoxy-α-D-glucopyranosyl-(1?4)]-2-deoxy-D-streptamine Sulfate Salt; O-3-Amino-3-deoxy-α-D-glucopyranosyl-(1?6)-O-[6-[[(2S)-4-amino-2-hydroxy-1-oxobutyl]amino]-6-deoxy-α-D-glucopyranosyl-(1?4)]-2-deoxy-D-streptamine Sulfate Salt; Antibiotic BB-K 6 Sulfate Salt; Amikacin EP Impurity E Sulfate. Grades: 97%. Molecular formula: C22H43N5O13.xH2SO4. Mole weight: 585.60 (free base). | |
| Bekanamycin | Bekanamycin (Kanamycin B) is an aminoglycoside antibiotic produced by Streptomyces kanamyceticus , against an array of Gram-positive and Gram-negative bacterial strain [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Kanamycin B. CAS No. 4696-76-8. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1174. | |
| Bis-3'',5-[N-(HABA-Cbz)] 3,6'-Di(N-benzyloxycarbonyl) Kanamycin A | Bis-3'',5-[N-(HABA-Cbz)] 3,6'-Di(N-benzyloxycarbonyl) Kanamycin A is an impurity of Amikacin, an semi-synthetic aminoglycoside antibotic derived from Kanamycin A. Molecular formula: C58H74N6O23. Mole weight: 1223.23. | |
| Bu-1709E1 | Bu-1709E1 is an aminoglycoside antibiotic produced by Bacillus circulans YQW-B-6. It has anti-gram-positive bacteria, negative bacteria and mycobacterial activity. Synonyms: Antibiotic Z-1159-1; D-Streptamine, O-2-amino-2-deoxy-alpha-D-glucopyranosyl-(1-4)-O-(beta-D-xylofuranosyl-(1-5))-N(sup 1)-(4-amino-2-hydroxy-1-oxobutyl)-2-deoxy-. CAS No. 54333-82-3. Molecular formula: C21H40N4O13. Mole weight: 556.56. | |
| Bu-1709E2 | Bu-1709E2 is an aminoglycoside antibiotic produced by Bacillus circulans YQW-B-6. It has anti-gram-positive bacteria, negative bacteria and mycobacterial activity. CAS No. 66749-41-5. Molecular formula: C21H40N4O13. Mole weight: 556.56. | |
| Butirosin | Butirosin is an aminoglycoside antibiotic produced by acillus circulans. It has activity against gram-positive bacteria, negative bacteria, and mycobacteria. It is not cross-resistant to gentamicin, and has an effect on some kanamycin-resistant bacteria. Synonyms: Ambutyrosin. CAS No. 12772-35-9. Molecular formula: C21H41N5O12. Mole weight: 555.57. | |
| Butirosin A | Butirosin A is an aminoglycoside antibiotic produced by acillus circulans. It has activity against gram-positive bacteria, negative bacteria, and mycobacteria. It is not cross-resistant to gentamicin, and has an effect on some kanamycin-resistant bacteria. Synonyms: Ambutyrosin A. Grades: 95%. CAS No. 34291-02-6. Molecular formula: C21H41N5O12. Mole weight: 555.57. | |
| [butirosin acyl-carrier protein]-L-glutamate ligase | Catalyses two steps in the biosynthesis of the side chain of the aminoglycoside antibiotics of the butirosin family. The enzyme adds one molecule of L-glutamate to a dedicated acyl-carrier protein, and following decarboxylation of the product by EC 4.1.1.95, L-glutamyl-[BtrI acyl-carrier protein] decarboxylase, adds a second L-glutamate molecule.Requires Mg2+ or Mn2+, and activity is enhanced in the presence of Mn2+. Group: Enzymes. Synonyms: [BtrI acyl-carrier protein]-L-glutamate ligase; BtrJ. Enzyme Commission Number: EC 6.2.1.39. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5697; [butirosin acyl-carrier protein]-L-glutamate ligase; EC 6.2.1.39; [BtrI acyl-carrier protein]-L-glutamate ligase; BtrJ. Cat No: EXWM-5697. | |
| Butirosin B | Butirosin B is an aminoglycoside antibiotic produced by acillus circulans. It has activity against gram-positive bacteria, negative bacteria, and mycobacteria. It is not cross-resistant to gentamicin, and has an effect on some kanamycin-resistant bacteria. Synonyms: Ambutyrosin B. CAS No. 34291-03-7. Molecular formula: C21H41N5O12. Mole weight: 555.57. | |
| Dactimicin | Dactimicin is an aminoglycoside antibiotic produced by Dactilosporangium matsuzakiense SF-2O52. It has anti-gram-positive and negative bacteria activity. Synonyms: SF-2052. Grades: >98%. CAS No. 73196-97-1. Molecular formula: C18H36N6O6. Mole weight: 432.51. | |
| Dactimicin sulfate | Dactimicin sulfate is an aminoglycoside antibiotic produced by Dactilosporangium matsuzakiense SF-2O52. It has anti-gram-positive and negative bacteria activity. Synonyms: Antibiotic SF 2052 sulfate; L-chiro-Inositol, 4-amino-1,4-dideoxy-3-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-beta-L-lyxo-heptopyranosyl)-6-O-methyl-1-(2-(formimidoylamino)-N-methylacetamido)-, sulfate (1:2), hydrate. Grades: >98%. CAS No. 73245-91-7. Molecular formula: C18H40N6O14S2. Mole weight: 628.67. | |
| Desamino 3''-Azido Tetra-N-Boc Tobramycin 6''-Carbamate O-Tetracetate | Desamino 3''-Azido Tetra-N-Boc Tobramycin 6''-Carbamate O-Tetracetate is an intermediate in the synthesis of derivatives of Tobramycin, an aminoglycoside antibiotic. Molecular formula: C47H76N8O22. Mole weight: 1105.15. | |
| Deshexamino Hexazido Tobramycin Tribenzyl Ether | Deshexamino Hexazido Tobramycin Tribenzyl Ether is an intermediate in the synthesis of derivatives of Tobramycin, an aminoglycoside antibiotic. Molecular formula: C39H44N18O8. Mole weight: 892.88. | |
| Despentamino Pentazido Tobramycin | Despentamino Pentazido Tobramycin is an intermediate in the synthesis of derivatives of Tobramycin, an aminoglycoside antibiotic. Synonyms: O-3-Azido-3-deoxy-α-D-glucopyranosyl-(1?6)-O-[2,6-diazido-2,3,6-trideoxy-α-D-ribo-hexopyranosyl-(1?4)]-1,3-diazido-1,2,3-trideoxy-D-myo-inositol. CAS No. 468065-22-7. Molecular formula: C18H27N15O9. Mole weight: 597.5. | |
| Despentamino Pentazido Tobramycin 6''-Carbamate Tetrabenzyl Ether | Despentamino Pentazido Tobramycin 6''-Carbamate Tetrabenzyl Ether is an intermediate in the synthesis of derivatives of Tobramycin, an aminoglycoside antibiotic. Molecular formula: C47H52N16O10. Mole weight: 1001.02. | |
| Despentamino Pentazido Tobramycin 6''-tert-Butyldimethysilyl Ether | Despentamino Pentazido Tobramycin 6''-tert-Butyldimethysilyl Ether is an intermediate in the synthesis of derivatives of Tobramycin, an aminoglycoside antibiotic. Molecular formula: C24H41N15O9Si. Mole weight: 711.76. | |
| Despentamino Pentazido Tobramycin Pentabenzyl Ether | Despentamino Pentazido Tobramycin Pentabenzyl Ether is an intermediate in the synthesis of derivatives of Tobramycin, an aminoglycoside antibiotic. Molecular formula: C53H57N15O9. Mole weight: 1048.11. | |
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