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3-Aminoisobutyricacid (β-Aminoisobutyricacid) has anti-inflammatory and antioxidant effects. 3-Aminoisobutyricacid increases the expression of brown adipocyte-specific genes in white adipose tissue and fatty acid β-oxidation in hepatocytes. 3-Aminoisobutyricacid attenuates insulin resistance and inflammation induced by palmitate or a high fat diet via an AMPK - PPARδ-dependent pathway in mice. 3-Aminoisobutyricacid is a catabolic metabolite of thymine and valine in skeletal muscle [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: β-Aminoisobutyricacid; BAIBA. CAS No. 144-90-1. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-W012974.
3-Aminoisobutyricacid (Standard)
3-Aminoisobutyricacid (Standard) is the analytical standard of 3-Aminoisobutyricacid. This product is used for research and analytical applications. 3-Aminoisobutyricacid (β-Aminoisobutyricacid) exhibits anti-inflammatory and antioxidant effects. It increases the expression of brown fat cell-specific genes in white adipose tissue and enhances fatty acid β-oxidation in hepatocytes. 3-Aminoisobutyricacid alleviates insulin resistance and inflammation induced by palmitic acid or a high-fat diet in mice via the AMPK - PPARδ -dependent pathway. 3-Aminoisobutyricacid is a catabolite of thymine and valine in skeletal muscle [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: β-Aminoisobutyricacid (Standard); BAIBA (Standard). CAS No. 144-90-1. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W012974R.
a-Aminoisobutyricacid 99+%
a-Aminoisobutyricacid 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 25g, 100g, 250g, 1Kg. US Biological Life Sciences.
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A-AMINOISOBUTYRICACID HYDROXAMATE
Heterocyclic Organic Compound. CAS No. 102185-21-7. Purity: 0.96. Catalog: ACM102185217.
3-Aminoisobutyricacid (or β-aminoisobutyricacid, BAIBA) is a product formed by the catabolism of thymine. During exercise, the increase of PGC-1α protein triggers the secretion of BAIBA from exercising muscles to blood (concentration 2 to 3uM in human serum). When BAIBA reaches the white fat tissue, it activates the expression of thermogenic genes via PPARα receptors, resulting in a browning of white fat cells. One of the consequences of the BAIBA activity is the increase of the background metabolism of the BAIBA target cells. It has recently been postulated to play a role in cell metabolism, how body burns fat and regulates insulin, triglycerides, and total cholesterol. Group: Biochemicals. Alternative Names: BAIBA; 3-amino-2-methylpropanoic acid; 2-(aminomethyl)propionic acid; 2-Methyl-beta-alanine3-Amino-2-methylpropanoate; 3-Aminoisobutanoate; 3-Aminoisobutanoic acid; 3-aminoisobutyricacid; alpha-Methyl-beta-alanine; β-aminoisobutyricacid; DL-beta-aminoisobutyricacid. Grades: Highly Purified. CAS No. 144-90-1. Pack Sizes: 1g, 5g, 10g, 25g. Molecular Formula: C?H?NO?, Molecular Weight: 103.12. US Biological Life Sciences.
2-[[[ (1, 1-Dimethylethoxy) carbonyl]amino]methyl]-propanoic-3, 3, 3-d3 Acid Phenylmethyl Ester is an intermediate in the synthesis of labelled 3-AminoisobutyricAcid (A611587). Unlabelled 3-AminoisobutyricAcid (A611585) is a substituted β-alanines and is used for preparation and isolation of D(-)- β-AminoisobutyricAcid. Group: Biochemicals. Grades: Highly Purified. CAS No. 375379-70-7. Pack Sizes: 25mg, 50mg. Molecular Formula: C16H20D3NO4. US Biological Life Sciences.
3-[(tert-Butoxycarbonyl)amino]-2-methylpropanoic-d3 Acid is labelled (R) -3- ( (tertButoxycarbonyl) amino) -2-methylpropanoic Acid (B692230), which has been used as a reactant in the preparation of cryptophycin B and arenastatin A, potent antiumor macrolides. 3-[(tert-Butoxycarbonyl)amino]-2-methylpropanoic-d3 Acid is an intermediate in the synthesis of labelled 3-AminoisobutyricAcid (A611587). Unlabelled 3-AminoisobutyricAcid (A611585) is a substituted β-alanines and is used for preparation and isolation of D(-)- β-AminoisobutyricAcid. Group: Biochemicals. Grades: Highly Purified. CAS No. 375379-71-8. Pack Sizes: 10mg, 25mg. Molecular Formula: C9H14D3NO4. US Biological Life Sciences.
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Alamethicin (Antibiotic U-22324)
Alamethicin is a peptide antibiotic, produced by the fungus Trichoderma viride. Alamethicin contains the non-proteinogenic amino acid 2-aminoisobutyricacid (Aib), which strongly induces helical peptide structures. In cell membranes, it forms voltage-dependent ion channels by aggregation of four to six molecules. Group: Biochemicals. Alternative Names: (3S,12R)-1-((S)-1-((6S,12S,15S,21S,30S)-1-((R)-1-(2-Acetamido-2- methylpropanoyl) pyrrolidin-2-yl) -15- (3-amino-3-oxopropyl) -30-isobutyl-21-isopropyl- 3, 3, 6, 9, 9, 2, 18, 18, 24, 24, 33, 33-dodecamethyl-1, 4, 7, 10, 13, 16, 19, 22, 25, 28, 31- undecaoxo-2, 5, 8, 11, 14, 17, 20, 23, 26, 29, 32-undecaazatetratri acontan-34- oyl)pyrrolidin-2-yl)-12-(((R)-5-amino-1-(((S)-1-hydroxy-3-phenylpropan-2-yl)amino)-1, 5-dioxopentan-2-yl)carbamoyl)-3-isopropyl-6,6,9,9-tetramethyl-1,4,7,10-tetraoxo-2,5, 8,11-tetraazapentadecan-15-oic Acid; Antibiotic U-22324. Grades: Purified. CAS No. 27061-78-5. Pack Sizes: 1mg, 5mg, 10mg. Molecular Formula: C??H???N??O??, Molecular Weight: 1964.31. US Biological Life Sciences.
Worldwide
Boc-Aib-OH
Standard building block for introduction of aminoisobutyricacid amino-acid residues by Boc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Boc-Aib-OH, N-α -t.-Boc-α -aminoisobutyricacid, N-α -t.-Boc-α -methylalanine. CAS No. 30992-29-1. Mole weight: 203.24. Catalog: ACM30992291.
Standard building block for introduction of aminoisobutyric amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Aib-OH, N-α -Fmoc-α -aminoisobutyricacid, N-Fmoc-C-α-methylalanine, Fmoc-alpha-aminoisobutyricacid. CAS No. 94744-50-0. Molecular formula: C19H19NO4. Mole weight: 325.36. Catalog: ACM94744500.
Fmoc-α-Me-Ala-OH-15N
Peptide synthesis. Group: Amino acids. Alternative Names: 2-Aminoisobutyricacid-15N, α-N-Fmoc. CAS No. 1019641-03-2. Mole weight: 326.35. Canonical SMILES: CC(C)([15NH]C(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O. Catalog: ACM1019641032.
ICI 174,864
ICI 174,864 is a potent and highly selective δ opioid antagonist. It shows partial agonist in vitro activity at δ receptors at high concentrations. Synonyms: ICI 174,864; ICI174,864; ICI-174,864; N,N-Di-2-propen-1-yl-L-tyrosyl-2-methylalanyl-L-phenylalanyl-L-leucine; NIH 10893; N,N-diallyl-tyrosyl-alpha-aminoisobutyricacid-phenylalanyl-leucine; L-Leucine, N-(N-(N-(N,N-di-2-propenyl-L-tyrosyl)-2-methylalanyl)-L-phenylalanyl)-; N,N-Diallyl-Tyr-aib-Phe-Leu. Grades: >98%. CAS No. 89352-67-0. Molecular formula: C38H53N5O7. Mole weight: 691.87.
(S)-3-amino-2-methylpropionate transaminase
Also acts on β-alanine and other ω-amino acids having carbon chains between 2 and 5. The two enantiomers of the 2-methyl-3-oxopropanoate formed by the enzyme interconvert by enolization, so that this enzyme, together with EC 2.6.1.40, (R)-3-amino-2-methylpropionate-pyruvate transaminase, provide a route for interconversion of the enantiomers of 3-amino-2-methylpropanoate. Group: Enzymes. Synonyms: L-3-aminoisobutyrate transaminase; β-aminobutyric transaminase; L-3-aminoisobutyric aminotransferase; β-aminoisobutyrate-α-ketoglutarate transaminase. Enzyme Commission Number: EC 2.6.1.22. CAS No. 9031-95-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2862; (S)-3-amino-2-methylpropionate transaminase; EC 2.6.1.22; 9031-95-2; L-3-aminoisobutyrate transaminase; β-aminobutyric transaminase; L-3-aminoisobutyric aminotransferase; β-aminoisobutyrate-α-ketoglutarate transaminase. Cat No: EXWM-2862.
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