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| Product | Description | |
|---|---|---|
| Aminopeptidase | Aminopeptidase catalyzes the cleavage of amino acids from the amino terminus of protein or peptide substrates [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 9031-94-1. Pack Sizes: 50 U; 100 U. Product ID: HY-P2842. |  |
| aminopeptidase B | Cytosolic or membrane-associated enzyme from mammalian tissues, activated by chloride ions and low concentrations of thiol compounds. This is one of the activities of the bifunctional enzyme EC 3.3.2.6 (membrane alanyl aminopeptidase family). Group: Enzymes. Synonyms: arylamidase II; arginine aminopeptidase; arginyl aminopeptidase; Cl--activated arginine aminopeptidase; cytosol aminopeptidase IV; L-arginine aminopeptidase. Enzyme Commission Number: EC 3.4.11.6. CAS No. 9073-92-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4027; aminopeptidase B; EC 3.4.11.6; 9073-92-1; arylamidase II; arginine aminopeptidase; arginyl aminopeptidase; Cl--activated arginine aminopeptidase; cytosol aminopeptidase IV; L-arginine aminopeptidase. Cat No: EXWM-4027. |  |
| aminopeptidase Ey | A zinc glycoprotein in peptidase family M1 (membrane alanyl aminopeptidase family), composed of two 150 kDa subunits. From the plasma fraction of hen egg yolk. Group: Enzymes. Enzyme Commission Number: EC 3.4.11.20. CAS No. 9031-94-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4017; aminopeptidase Ey; EC 3.4.11.20; 9031-94-1. Cat No: EXWM-4017. | |
| Aminopeptidase from Aeromonas, Recombinant | Aeromonas Aminopeptidase is used in the processing of pharmaceutical proteins produces by genetic engineering as well as for physical and structural investigations and for sequence and amino-terminal determinations. This exopeptidase recognizes a specific stop sign at -X-Pro and requires a free a-amino group in the L-configuration. It is therefore suitable for the removal of the redundant N-terminal methionine often added to engineered recombinant proteins. Group: Enzymes. Synonyms: Aeromonas Aminopeptidase; Aminopeptidase. Aminopeptidase. Activity: 120 Units/mg protein. Stability: Two years when stored at -20°C, 2 weeks at 4°C. Please avoid freeze-thaw cycles. Appearance: Sterile filtered liquid formulation. Source: Aeromonas. Aeromonas Aminopeptidase; Aminopeptidase. Cat No: NATE-0811. | |
| aminopeptidase I | A 640-kDa, dodecameric enzyme best known as the major vacuolar aminopeptidase of yeast, Saccharomyces cervisiae, in which species it was first given the name aminopeptidase I (one), amongst others. Activity is stimulated by both Zn2+ and Cl- ions. Type example of peptidase family M18. Group: Enzymes. Synonyms: aminopeptidase III; aminopeptidase yscI; leucine aminopeptidase IV; yeast aminopeptidase I. Enzyme Commission Number: EC 3.4.11.22. CAS No. 9031-94-1. Aminopeptidase I. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4019; aminopeptidase I; EC 3.4.11.22; 9031-94-1; aminopeptidase III; aminopeptidase yscI; leucine aminopeptidase IV; yeast aminopeptidase I. Cat No: EXWM-4019. | |
| Aminopeptidase N Inhibitor | Membrane alanyl aminopeptidase is also known as alanyl aminopeptidase (AAP) or aminopeptidase N (AP-N), which is an enzyme that in humans is encoded by the ANPEP gene. Aminopeptidase N (AP-N) inhibitor is a reversible inhibitor of AP-N/CD13 (IC50 = 25 μM). It is selective for AP-N/CD13 over matrix metalloproteinase-9 (MMP-9), angiotensin converting enzyme (ACE), neutral endopeptidase (NEP), γ-glutamyl transpeptidase, and the serine proteases dipeptidyl peptidase 4 (DPP-4) and cathepsin G at a concentration of 1 mM. AP-N inhibitor is non-cytotoxic to U937 cells at a concentration of 100 μM. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma. Synonyms: AP-N Inhibitor. Grades: ≥95%. CAS No. 596108-59-7. Molecular formula: C17H10N2O8. Mole weight: 370.27. |  |
| Aminopeptidase N Ligand (CD13), NGR peptide | It is a peptide with NGR (Asn-Gly-Arg) motif, which has a disulfide bridge linking cys1 and cys5, and is known to have antimicrobial properties in addition to the presence of KLA sequences. The peptide binds to CD13 on tumor cells and shows strong cytotoxicity and activity against tumor cells. This peptide shows dose-dependent antiproliferation against tumor cells and induces cell cylce arrest at G2/M phases and apoptosis of the tumor cells. Peptides containing the NGR motif are useful in the delivery of cytotoxic drugs, pro-apoptotic peptides, and tumor necrosis factor (TNF) into tumor vasculature. Synonyms: H-Cys-Asn-Gly-Arg-Cys-Gly-OH (Disulfide bridge: Cys1-Cys5); L-cysteinyl-L-asparagyl-glycyl-L-arginyl-L-cysteinyl-glycine (1->5)-disulfide; N-{[(4R,5E,7S,8E,11E,13S,14E,16R)-16-Amino-7-(3-carbamimidamidopropyl)-6,9,12,15-tetrahydroxy-13-(2-hydroxy-2-iminoethyl)-1,2-dithia-5,8,11,14-tetraazacycloheptadeca-5,8,11,14-tetraen-4-yl](hydroxy)methylene}glycine. Grades: ≥95%. Molecular formula: C20H34N10O8S2. Mole weight: 606.67. | |
| aminopeptidase S | Aminopeptidases are associated with many biological functions, including protein maturation, protein degradation, cell-cycle control and hormone-level regulation. This enzyme contains two zinc molecules in its active site and is activated by Ca2+. In the presence of Ca2+, the best substrates are Leu-Phe, Leu-Ser, Leu-pNA (aminoacyl-p-nitroanilide), Phe-Phe-Phe and Phe-Phe. Peptides with proline in the P1' position are not substrates. Belongs in peptidase family M28. Group: Enzymes. Synonyms: Mername-AA022 peptidase; SGAP; aminopeptidase (Streptomyces griseus); Streptomyces griseus aminopeptidase; S. griseus AP; double-zinc aminopeptidase. Enzyme Commission Number: EC 3.4.11.24. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4021; aminopeptidase S; EC 3.4.11.24; Mername-AA022 peptidase; SGAP; aminopeptidase (Streptomyces griseus); Streptomyces griseus aminopeptidase; S. griseus AP; double-zinc aminopeptidase. Cat No: EXWM-4021. | |
| aminopeptidase Y | Requires Co2+; inhibited by Zn2+ and Mn2+. An enzyme best known from Saccharomyces cerevisiae that hydrolyses Lys-NHPhNO2 and, more slowly, Arg-NHPhNO2. Type example of peptidase family M28. Group: Enzymes. Synonyms: aminopeptidase Co; aminopeptidase (cobalt-activated); lysyl aminopeptidase. Enzyme Commission Number: EC 3.4.11.15. CAS No. 114796-97-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4011; aminopeptidase Y; EC 3.4.11.15; 114796-97-3; aminopeptidase Co; aminopeptidase (cobalt-activated); lysyl aminopeptidase. Cat No: EXWM-4011. | |
| aspartyl aminopeptidase | Aminoacyl-arylamides are poor substrates. This is an abundant cytosolic enzyme in mammalian cells, in peptidase family M18 of aminopeptidase I. Group: Enzymes. Enzyme Commission Number: EC 3.4.11.21. CAS No. 9074-83-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4018; aspartyl aminopeptidase; EC 3.4.11.21; 9074-83-3. Cat No: EXWM-4018. | |
| bacterial leucyl aminopeptidase | A zinc enzyme. Forms of the enzyme have been isolated from Aeromonas proteolytica, Escherichia coli and Streptococcus thermophilus. Examples are known from peptidase families M17 and M28 (of leucyl aminopeptidase and aminopeptidase Y, respectively). Group: Enzymes. Synonyms: Aeromonas proteolytica aminopeptidase. Enzyme Commission Number: EC 3.4.11.10. CAS No. 37288-67-8. Aminopeptidase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4008; bacterial leucyl aminopeptidase; EC 3.4.11.10; 37288-67-8; Aeromonas proteolytica aminopeptidase. Cat No: EXWM-4008. | |
| β-peptidyl aminopeptidase | Sphingosinicella xenopeptidilytica strain 3-2W4 is able to utilize the β-peptides β-homoVal-β-homoAla-β-homoLeu and β-homoAla-β-homoLeu as sole carbon and energy sources. Group: Enzymes. Synonyms: BapA (ambiguous). Enzyme Commission Number: EC 3.4.11.25. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4022; β-peptidyl aminopeptidase; EC 3.4.11.25; BapA (ambiguous). Cat No: EXWM-4022. | |
| clostridial aminopeptidase | A secreted enzyme from Clostridium histolyticum, requiring Mn2+ or Co2+. Group: Enzymes. Synonyms: Clostridium histolyticum aminopeptidase. Enzyme Commission Number: EC 3.4.11.13. CAS No. 59680-69-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4009; clostridial aminopeptidase; EC 3.4.11.13; 59680-69-2; Clostridium histolyticum aminopeptidase. Cat No: EXWM-4009. | |
| cystinyl aminopeptidase | A zinc-containing sialoglycoprotein in peptidase family M1 (membrane alanyl aminopeptidase family). Group: Enzymes. Synonyms: cystyl-aminopeptidase; oxytocinase; cystine aminopeptidase; L-cystine aminopeptidase; oxytocin peptidase; vasopresssinase. Enzyme Commission Number: EC 3.4.11.3. CAS No. 9031-41-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4024; cystinyl aminopeptidase; EC 3.4.11.3; 9031-41-8; cystyl-aminopeptidase; oxytocinase; cystine aminopeptidase; L-cystine aminopeptidase; oxytocin peptidase; vasopresssinase. Cat No: EXWM-4024. | |
| cytosol alanyl aminopeptidase | A puromycin-sensitive, Co2+-activated zinc-sialoglycoprotein that is generally cytosolic. Multiple forms are widely distributed in mammalian tissues and body fluids. In peptidase family M1 (membrane alanyl aminopeptidase family). Group: Enzymes. Synonyms: arylamidase; aminopolypeptidase; thiol-activated aminopeptidase; human liver aminopeptidase; puromycin-sensitive aminopeptidase; soluble alanyl aminopeptidase; cytosol aminopeptidase III; alanine aminopeptidase. Enzyme Commission Number: EC 3.4.11.14. CAS No. 243859-94-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4010; cytosol alanyl aminopeptidase; EC 3.4.11.14; 243859-94-1; arylamidase; aminopolypeptidase; thiol-activated aminopeptidase; human liver aminopeptidase; puromycin-sensitive aminopeptidase; soluble alanyl aminopeptidase; cytosol aminopeptidase III; alanine aminopeptidase. Cat No: EXWM-4010. | |
| D-stereospecific aminopeptidase | Known from the bacterium Ochrobactrum anthropi. In peptidase family S12 (D-Ala-D-Ala carboxypeptidase family). Group: Enzymes. Synonyms: D-aminopeptidase. Enzyme Commission Number: EC 3.4.11.19. CAS No. 57534-78-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4015; D-stereospecific aminopeptidase; EC 3.4.11.19; 57534-78-8; D-aminopeptidase. Cat No: EXWM-4015. | |
| glutamyl aminopeptidase | Ca2+-activated and generally membrane-bound. A zinc-metallopeptidase in family M1 (membrane alanyl aminopeptidase family). Group: Enzymes. Synonyms: aminopeptidase A; aspartate aminopeptidase; angiotensinase A; glutamyl peptidase; Ca2+-activated glutamate aminopeptidase; membrane aminopeptidase II; antigen BP-1/6C3 of mouse B lymphocytes; L-aspartate aminopeptidase; angiotensinase A2. Enzyme Commission Number: EC 3.4.11.7. CAS No. 9074-83-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4028; glutamyl aminopeptidase; EC 3.4.11.7; 9074-83-3; aminopeptidase A; aspartate aminopeptidase; angiotensinase A; glutamyl peptidase; Ca2+-activated glutamate aminopeptidase; membrane aminopeptidase II; antigen BP-1/6C3 of mouse B lymphocytes; L-aspartate aminopeptidase; angiotensinase A2. Cat No: EXWM-4028. | |
| leucyl aminopeptidase | A zinc enzyme isolated from pig kidney and cattle lens; activated by heavy metal ions. Type example of peptidase family M17. Group: Enzymes. Synonyms: leucine aminopeptidase; leucyl peptidase; peptidase S; cytosol aminopeptidase; cathepsin III; L-leucine aminopeptidase; leucinaminopeptidase; leucinamide aminopeptidase; FTBL proteins; proteinates FTBL; aminopeptidase II; aminopeptidase III; aminopeptidase I. Enzyme Commission Number: EC 3.4.11.1. CAS No. 9001-61-0. LAP. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4007; leucyl aminopeptidase; EC 3.4.11.1; 9001-61-0; leucine aminopeptidase; leucyl peptidase; peptidase S; cytosol aminopeptidase; cathepsin III; L-leucine aminopeptidase; leucinaminopeptidase; leucinamide aminopeptidase; FTBL proteins; proteinates FTBL; aminopeptidase II; aminopeptidase III; aminopeptidase I. Cat No: EXWM-4007. | |
| membrane alanyl aminopeptidase | A zinc enzyme, not activated by heavy metal ions. Type example of peptidase family M1. Group: Enzymes. Synonyms: microsomal aminopeptidase; aminopeptidase M; aminopeptidase N; particle-bound aminopeptidase; amino-oligopeptidase; alanine aminopeptidase; membrane aminopeptidase I; pseudo leucine aminopeptidase; alanyl aminopeptidase; alanine-specific aminopeptidase; cysteinylglycine dipeptidase; cysteinylglycinase; L-alanine aminopeptidase; CD13. Enzyme Commission Number: EC 3.4.11.2. CAS No. 9054-63-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4016; membrane alanyl aminopeptidase; EC 3.4.11.2; 9054-63-1; microsomal aminopeptidase; aminopeptidase M; aminopeptidase N; particle-bound aminopeptidase; amino-oligopeptidase; alanine aminopeptidase; membrane aminopeptidase I; pseudo leucine aminopeptidase; alanyl aminopeptidase; alanine-specific aminopeptidase; cysteinylglycine dipeptidase; cysteinylglycinase; L-alanine aminopeptidase; CD13. Cat No: EXWM-4016. | |
| Methionine Aminopeptidase from Pyrococcus furiosus, Recombinant | Methionyl aminopeptidase (EC 3.4.11.18, methionine aminopeptidase, peptidase M, L-methionine aminopeptidase, MAP) is an enzyme. This enzyme catalyses the following chemical reaction:Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides. This membrane-bound enzyme is present in both prokaryotes and eukaryotes. X-ray crystallography of the structure of methionine aminopeptidase from pyrococcus furiosus or pfmap was performed at a resolution of 1.75a and showed that the protein consists of a catalytic domain containing two cobalt ions in the active site and a unique insertion domain which is specific to the prokaryotic form of...o the methionyl aminopeptidases from escherichia coli and pyrococcus furiosus. it has also been used in a study to examine the binding of a new class of pseudopeptide analog inhibitors. Group: Enzymes. Synonyms: Methionyl aminopeptidase; EC 3.4.11.18; methionine aminopeptidase; peptidase M; L-methionine aminopeptidase; MAP. Enzyme Commission Number: EC 3.4.11.18. CAS No. 9025-42-7. MAP. Storage: -20°C. Form: Solution containing 0.01% Tween 20, 0.1 mM CoCl2, and 10 mM Tris-HCl, pH 7.5. Source: E. coli. Species: Pyrococcus furiosus. Methionyl aminopeptidase; EC 3.4.11.18; methionine aminopeptidase; peptidase M; L-methionine aminopeptidase; MAP. Cat No: NATE-0442. | |
| methionyl aminopeptidase | This membrane-bound enzyme, which is present in both prokaryotes and eukaryotes, releases the initiator methionine from nascent peptides. The activity is dependent on the identity of the second, third and fourth amino acid residues of the target protein, but in general the enzyme acts only when the penultimate residue is small and uncharged (e.g. Gly, Ala, Cys, Ser, Thr, and Val). Group: Enzymes. Synonyms: methionine aminopeptidase; peptidase M; L-methionine aminopeptidase; MAP. Enzyme Commission Number: EC 3.4.11.18. CAS No. 61229-81-0. MAP. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4014; methionyl aminopeptidase; EC 3.4.11.18; 61229-81-0; methionine aminopeptidase; peptidase M; L-methionine aminopeptidase; MAP. Cat No: EXWM-4014. | |
| Native Aeromonas proteolytica Aminopeptidase | Aminopeptidase from Aeromonas proteolytica is a metalloenzyme, which contains 2 atoms of Zn2+ in a single polypeptide with an approximate molecular weight of 29.5 kDa as determined by sedimentation. This enzyme has a high degree of stability, being stable even at tempeRatures of 70°C for several hours. Partial inactivation occurs in 8 M urea. Maximum stability and activity are between pH 8.0-8.5. Aminopeptidase from Aeromonas proteolytica can function as an esterase. Applications: Aminopeptidases are a family of widely distributed proteases, which may be used to study many significant biological processes such as protein maturation, hormone production, and peptide digestion. the enzyme has been used to measure the kinetic rate constant for the binding of bestatin, a general protease inhibitor, to aminopeptidase. Group: Enzymes. Synonyms: Aminopeptidase; 37288-67-8; EC 3.4.11.10; Aeromonas proteolytica aminopeptidase. Enzyme Commission Number: EC 3.4.11.10. CAS No. 37288-67-8. Aminopeptidase. Storage: -20°C. Form: lyophilized powder, 50-150 units/mg protein. Source: Aeromonas proteolytica. Aminopeptidase; 37288-67-8; EC 3.4.11.10; Aeromonas proteolytica aminopeptidase. Cat No: NATE-0071. | |
| Native Bacillus sp. Pyroglutamate Aminopeptidase | Pyroglutamate aminopetidase is an enzyme that digests proteins. Applications: Pyroglutamate aminopetidase is used to digest proteins for subsequent analysis, such as amino acid sequencing. pyroglutamate aminopeptidase is used to hydrolyze and activate various prodrugs. Group: Enzymes. Synonyms: pyroglutamyl-peptidase I; Pyroglutamate aminopeptidase; EC 3.4.19.3; 5-oxoprolyl-peptidase; pyrase; pyroglutamate aminopeptidase; pyroglutamyl aminopeptidase; L-pyroglutamyl peptide hydrolase; pyrrolidone-carboxyl peptidase; pyrrolidone-carboxylate peptidase; pyrrolidonyl peptidase; L-pyrrolidonecarboxylate peptidase; pyroglutamidase; pyrrolidonecarboxylyl peptidase; 9075-21-2. Enzyme Commission Number: EC 3.4.19.3. CAS No. 9075-21-2. Pyrase. Activity: > 0.11 units/mg protein. Storage: -20°C. Source: Bacillus sp. pyroglutamyl-peptidase I; Pyroglutamate aminopeptidase; EC 3.4.19.3; 5-oxoprolyl-peptidase; pyrase; pyroglutamate aminopeptidase; pyroglutamyl aminopeptidase; L-pyroglutamyl peptide hydrolase; pyrrolidone-carboxyl peptidase; pyrrolidone-carboxylate peptidase; pyrrolidonyl peptidase; L-pyrrolidonecarboxylate peptidase; pyroglutamidase; pyrrolidonecarboxylyl peptidase; 9075-21-2. Cat No: NATE-0647. | |
| Native Porcine Aminopeptidase M | Native amino peptidase M from porcine kidney. Metalloprotease that hydrolyzes N-terminal amino acids from almost all unsubstituted oligopeptides. Does not cleave X-Pro bonds or N-blocked amino acids. Useful in peptide sequencing. Inhibited by EDTA, bestatin, and amastatin. Group: Enzymes. Synonyms: Aminopeptidase M. Enzyme Commission Number: EC 3.4.11.2. CAS No. 9054-63-1. Aminopeptidase M. Activity: > 50 units/ml. Stability: Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C. Appearance: White crystalline suspension. Storage: 2 - 8°C. Source: Porcine kidney. Species: Porcine. Aminopeptidase M. Cat No: NATE-1912. | |
| Native Porcine Leucine Aminopeptidase | Leucine aminopeptidase (LAP) is a proteolytic enzyme which hydrolyzes the peptide bond adjacent to a free amino group. It is called leucine aminopeptidase because it rapidly catalyzes the hydrolysis of leucine containing peptides. However, it also catalyzes the hydrolytic release of other amino acids located at the N-terminal end of various peptides and proteins. The enzyme from porcine kidney has been extensively studied. It has a molecular weight of 255,000 and it consists of four subunits each having one atom of zinc. Group: Enzymes. Synonyms: Leucine Aminopeptidase; 9054-63-1; leucyl peptidase; peptidase S; cytosol aminopeptidase; cathepsin III; L-leucine aminopeptidase; leucinaminopeptidase; leucinamide aminopeptidase; FTBL proteins; proteinates FTBL; aminopeptidase II; aminopeptidase III; aminopeptidas. Enzyme Commission Number: EC 3.4.11.1. Purity: 90% (biuret). LAP. Activity: >100 U/mg protein. Storage: Stable when stored at 4°C. Do not freeze. Form: Ammonium Sulfate. Source: Porcine Kidney. Species: Porcine. Leucine Aminopeptidase; 9054-63-1; leucyl peptidase; peptidase S; cytosol aminopeptidase; cathepsin III; L-leucine aminopeptidase; leucinaminopeptidase; leucinamide aminopeptidase; FTBL proteins; proteinates FTBL; aminopeptidase II; aminopeptidase III; aminopeptidase I; EC 3.4.11.1; leucyl aminopeptidase; LAP. Cat No: NATE-1879. | |
| Native Porcine Leucine Aminopeptidase, microsomal | Leucyl aminopeptidases are enzymes that preferentially catalyze the hydrolysis of leucine residues at the N-terminus of peptides and proteins. Other N-terminal residues can also be cleaved, however. LAPs have been found across superkingdoms. Identified LAPs include human LAP, bovine lens LAP, porcine LAP, Escherichia coli (E. coli) LAP (also known as PepA or XerB), and the solanaceous-specific acidic LAP (LAP-A) in tomato (Solanum lycopersicum). Group: Enzymes. Synonyms: Leucine Aminopeptidase, microsomal; 9054-63-1; leucine aminopeptidase; leucyl peptidase; peptidase S; cytosol aminopeptidase; cathepsin III; L-leucine aminopeptidase; leucinaminopeptidase; leucinamide aminopeptidase; FTBL prot. Enzyme Commission Number: EC 3.4.11.1. CAS No. 9054-63-1. LAP. Activity: Type VI-S, > 12 units/mg protein (biuret); Type IV-S, 10-40 units/mg protein (Bradford). Form: Type VI-S, lyophilized powder; Type IV-S, ammonium sulfate suspension. Source: Porcine kidney. Species: Porcine. Leucine Aminopeptidase, microsomal; 9054-63-1; leucine aminopeptidase; leucyl peptidase; peptidase S; cytosol aminopeptidase; cathepsin III; L-leucine aminopeptidase; leucinaminopeptidase; leucinamide aminopeptidase; FTBL proteins; proteinates FTBL; aminopeptidase II; aminopeptidase III; aminopeptidase I; EC 3.4.11.1; leucyl aminopeptidase; LAP. Cat No: NATE-0378. | |
| Native Streptomyces griseus Aminopeptidase I | Aminopeptidase I from S. griseus has a fairly broad specificity, being able to remove the N-terminal residue of most proteins, except where the penultimate residue is an imino acid. It contains two Zn2+ binding sites. Aminopeptidase I from S. griseus is inhibited by 1,10-phenanthroline and is activated six-fold by Ca2+, which also stabilizes it against heat inactivation. This monomeric zinc metalloprotein has an isoelectric point (pI) of 5.4. Applications: Aminopeptidase i from streptomyces griseus may be used as a reagent for the analysis of protein structure and as a model for studies of proteolytic enzyme activation by calcium ions. it may be used as a reagent in the assay of endoprotease activities with a synthetic substrate in a two-stage assay. the lyophilized powder also contains calcium acetate. Group: Enzymes. Synonyms: aminopeptidase III; aminopeptidase yscI; leucine aminopeptidase IV; yeast aminopeptidase I; EC 3.4.11.22; 9031-94-1; Aminopeptidase I. Enzyme Commission Number: EC 3.4.11.22. CAS No. 9031-94-1. Aminopeptidase I. Activity: > 200 units/mg protein. Storage: -20°C. Form: lyophilized powder. Contains calcium acetate. Source: Streptomyces griseus. aminopeptidase III; aminopeptidase yscI; leucine aminopeptidase IV; yeast aminopeptidase I; EC 3.4.11.22; 9031-94-1; Aminopeptidase I. Cat No: NATE-0070. | |
| Native Thermococcus thioreducens Pyroglutamate Aminopeptidase | Pyroglutamate aminopetidase is an enzyme that digests proteins. This enzyme is specific for N-terminal pyroglutamic acids. It cleaves the N-terminal pyroglutamic acid from proteins and peptides prior to Edman degradation. The optimal temperature range is 95 to 100°C and the optimal pH range is 6.0 to 9.0. Group: Enzymes. Synonyms: pyroglutamyl-peptidase I; Pyroglutamate aminopeptidase; EC 3.4.19.3; 5-oxoprolyl-peptidase; pyrase; pyroglutamate aminopeptidase; pyroglutamyl aminopeptidase; L-pyroglutamyl peptide hydrolase; pyrrolidone-carboxyl peptidase; pyrrolidone-carboxylate peptidase; pyrrolidonyl peptidase; L-pyrrolidonecarboxylate peptidase; pyroglutamidase; pyrrolidonecarboxylyl peptidase; 9075-21-2. Purity: ~ 90% (SDS PAGE). Pyrase. Mole weight: 21.5 kDa. Activity: 20 U/mg. Storage: at -20°C. Form: Lyophilized powder. Source: Thermococcus thioreducens. pyroglutamyl-peptidase I; Pyroglutamate aminopeptidase; EC 3.4.19.3; 5-oxoprolyl-peptidase; pyrase; pyroglutamate aminopeptidase; pyroglutamyl aminopeptidase; L-pyroglutamyl peptide hydrolase; pyrrolidone-carboxyl peptidase; pyrrolidone-carboxylate peptidase; pyrrolidonyl peptidase; L-pyrrolidonecarboxylate peptidase; pyroglutamidase; pyrrolidonecarboxylyl peptidase; 9075-21-2. Cat No: NATE-1256. | |
| PepB aminopeptidase | A 270-kDa protein composed of six 46.3-kDa subunits. The pH optimum is in the alkaline range and activity is stimulated by KCl. In peptidase family M17. Group: Enzymes. Synonyms: Salmonella enterica serovar Typhimurium peptidase B. Enzyme Commission Number: EC 3.4.11.23. CAS No. 928346-44-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4020; PepB aminopeptidase; EC 3.4.11.23; 928346-44-5; Salmonella enterica serovar Typhimurium peptidase B. Cat No: EXWM-4020. | |
| prolyl aminopeptidase | A Mn2+-requiring enzyme present in the cytosol of mammalian and microbial cells. In contrast to the mammalian form, the bacterial form of the enzyme (type example of peptidase family S33) hydrolyses both polyproline and prolyl-2-naphthylamide. The mammalian enzyme, which is not specific for prolyl bonds, is possibly identical with EC 3.4.11.1, leucyl aminopeptidase. Group: Enzymes. Synonyms: proline aminopeptidase; Pro-X aminopeptidase; cytosol aminopeptidase V; proline iminopeptidase. Enzyme Commission Number: EC 3.4.11.5. CAS No. 9025-40-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4026; prolyl aminopeptidase; EC 3.4.11.5; 9025-40-5; proline aminopeptidase; Pro-X aminopeptidase; cytosol aminopeptidase V; proline iminopeptidase. Cat No: EXWM-4026. | |
| Pyroglutamate Aminopeptidase from Pyrococcus furiosus, Recombinant | Pyroglutamate aminopetidase is an enzyme that digests proteins. This enzyme is specific for N-terminal pyroglutamic acids. It cleaves the N-terminal pyroglutamic acid from proteins and peptides prior to Edman degradation. The optimal temperature range is 95 to 100°C and the optimal pH range is 6.0 to 9.0. Recombinant, expressed in e. coli, ~90% (sds-page). Applications: Thermostable aminopeptidase that liberates n-terminal pyroglutamic acid from proteins and peptides prior to edman degradation. pyroglutamate aminopeptidase, from pyrococcus furiosus is a recombinant, thermostable aminopeptidase that is expressed in escherichia coli. it is used to cleave pyrogl...5-21-2. Enzyme Commission Number: EC 3.4.19.3. CAS No. 9075-21-2. Pyrase. Mole weight: mol wt 24.072 kDa by amino acid sequence mol wt 28 kDa by SDS-PAGE. Activity: > 0.11 units/mg protein. Storage: -20°C. Form: Lyophilized powder containing sodium phosphate. Source: E. coli. Species: Pyrococcus furiosus. pyroglutamyl-peptidase I; Pyroglutamate aminopeptidase; EC 3.4.19.3; 5-oxoprolyl-peptidase; pyrase; pyroglutamate aminopeptidase; pyroglutamyl aminopeptidase; L-pyroglutamyl peptide hydrolase; pyrrolidone-carboxyl peptidase; pyrrolidone-carboxylate peptidase; pyrrolidonyl peptidase; L-pyrrolidonecarboxylate peptidase; pyroglutamidase; pyrrolidonecarboxylyl p | |
| Recombinant Methionine aminopeptidase from E.coli | Methionine aminopeptidase (MetAP) catalyzes the hydrolytic cleavage of the N-terminal methionine from newly synthesized polypeptides. Group: Enzymes. Synonyms: MetAP; EC 3.4.11.18; 61229-81-0; methionine aminopeptidase; peptidase M; L-methionine aminopeptidase; MAP. Enzyme Commission Number: EC 3.4.11.18. CAS No. 61229-81-0. Purity: > 80 %. MAP. Mole weight: 29 kDa. Appearance: Colourless clear liquid. Storage: Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C. Source: E. coli. Species: E. coli. MetAP; EC 3.4.11.18; 61229-81-0; methionine aminopeptidase; peptidase M; L-methionine aminopeptidase; MAP. Cat No: NATE-1018. | |
| TNP-470 (AGM-1470, O-(Chloroacetyl-carbamoyl)fumagillol, AGM1470, MetAP-2 Inhibitor II, MetAP2 Inhibitor II, Methionine Aminopeptidase 2 Inhibitor II, TNP470) | A cell-permeable Fumagillin analog that inhibits MetAP2, but not MetAP1, methionine aminopeptidase activity (IC50 = 1nM against human MetAP2), without affecting the inhibitory activity of MetAP2 against HRI- (heme-regulated inhibitor kinase) catalyzed eIF-2alpha phosphorylation. A potent endothelial cytostasis inducer (IC50 = 25 pM and 37 pM, respectively, against HUVEC and bovine BAEC) in vitro and an effective anti-angiogenesis agent in vivo (2-100mg/kg in mice and rats; s.c.). Group: Biochemicals. Grades: Highly Purified. CAS No. 129298-91-5. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| tripeptide aminopeptidase | A zinc enzyme, widely distributed in mammalian tissues. Formerly EC 3.4.1.3. Group: Enzymes. Synonyms: tripeptidase; aminotripeptidase; aminoexotripeptidase; lymphopeptidase; imidoendopeptidase; peptidase B; alanine-phenylalanine-proline arylamidase; peptidase T. Enzyme Commission Number: EC 3.4.11.4. CAS No. 9056-26-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4025; tripeptide aminopeptidase; EC 3.4.11.4; 9056-26-2; tripeptidase; aminotripeptidase; aminoexotripeptidase; lymphopeptidase; imidoendopeptidase; peptidase B; alanine-phenylalanine-proline arylamidase; peptidase T. Cat No: EXWM-4025. | |
| tryptophanyl aminopeptidase | From Trichosporon cutaneum. Also acts on L-tryptophanamide. Requires Mn2+. Group: Enzymes. Synonyms: tryptophan aminopeptidase; L-tryptophan aminopeptidase. Enzyme Commission Number: EC 3.4.11.17. CAS No. 76689-19-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4013; tryptophanyl aminopeptidase; EC 3.4.11.17; 76689-19-5; tryptophan aminopeptidase; L-tryptophan aminopeptidase. Cat No: EXWM-4013. | |
| Xaa-Pro aminopeptidase | A Mn2+-dependent, generally membrane-bound enzyme present in both mammalian and bacterial cells. In peptidase family M24 (methionyl aminopeptidase family). Group: Enzymes. Synonyms: proline aminopeptidase; aminopeptidase P; aminoacylproline aminopeptidase; X-Pro aminopeptidase. Enzyme Commission Number: EC 3.4.11.9. CAS No. 37288-66-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4029; Xaa-Pro aminopeptidase; EC 3.4.11.9; 37288-66-7; proline aminopeptidase; aminopeptidase P; aminoacylproline aminopeptidase; X-Pro aminopeptidase. Cat No: EXWM-4029. | |
| Xaa-Trp aminopeptidase | A glycoprotein containing Zn2+, from renal and intestinal brush border membranes. Group: Enzymes. Synonyms: aminopeptidase W; aminopeptidase X-Trp; X-Trp aminopeptidase. Enzyme Commission Number: EC 3.4.11.16. CAS No. 137010-33-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4012; Xaa-Trp aminopeptidase; EC 3.4.11.16; 137010-33-4; aminopeptidase W; aminopeptidase X-Trp; X-Trp aminopeptidase. Cat No: EXWM-4012. | |
| 2-Methoxy-4-nitrobenzonitrile | 2-Methoxy-4-nitrobenzonitrile is a dual and selective inhibitor of dynamin-related protein 1 (Drp1) and puromycin-sensitive aminopeptidase (PSA). Group: Biochemicals. Grades: Highly Purified. CAS No. 101084-96-2. Pack Sizes: 100mg, 250mg. Molecular Formula: C8H6N2O3, Molecular Weight: 178.14. US Biological Life Sciences. | Worldwide |
| A 357300 hydrochloride | A 357300 hydrochloride is a potent and reversible inhibitor of methionine aminopeptidase-2 (MetAP-2). In murine models, it significantly inhibits CHP-134-derived neuroblastoma s.c. xenograft growth rate with a treatment-to-control (T/C) ratio at day 24 of 0.19 (P < 0.001) without toxicity. Uses: Novel treatment of neuroblastoma. Synonyms: A-357300; A 357300; A357300; N'-(3-amino-2-hydroxy-5-(isopropylthio)pentanoyl)-3-chlorobenzohydrazide hydrochloride. Grades: 99%. CAS No. 369358-07-6. Molecular formula: C15H22ClN3O3S.HCl. Mole weight: 396.33. | |
| Acetyl 1-L-leucyL-L-arginine | Acetyl 1-L-leucyL-L-arginine is a lactone compound isolated from the Bacterium sp. BMG520-yF2. Acetyl 1-L-leucyL-L-arginine has the activity of inhibiting dipeptidyl aminopeptidase ?. Molecular formula: C14H27N5O3. Mole weight: 313.39. | |
| Actinonin | Actinonin ((-)-Actinonin) is a naturally occurring antibacterial agent produced by Actinomyces. Actinonin inhibits aminopeptidase M , aminopeptidase N and leucine aminopeptidase. Actinonin is a potent reversible peptide deformylase (PDF) inhibitor with a K i of 0.28 nM. Actinonin also inhibits MMP-1 , MMP-3 , MMP-8 , MMP-9 , and hmeprin α with K i values of 300 nM, 1,700 nM, 190 nM, 330 nM, and 20 nM, respectively. Actinonin is an apoptosis inducer. Actinonin has antiproliferative and antitumor activities [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: (-)-Actinonin. CAS No. 13434-13-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113952. | |
| acylaminoacyl-peptidase | Active at neutral pH. Several variants of this enzyme exist; the human erythrocyte enzyme is relatively specific for removal of N-acetylalanine from peptides. Displays dipeptidyl-peptidase activity on glycyl-peptides, perhaps as a result of mis-recognition of the glycyl residue as an uncharged N-acyl group. Inhibited by diisopropyl fluorophosphate. In peptidase family S9 (prolyl oligopeptidase family). Group: Enzymes. Synonyms: acylamino-acid-releasing enzyme; N-acylpeptide hydrolase; N-formylmethionine (fMet) aminopeptidase; α-N-acylpeptide hydrolase. Enzyme Commission Number: EC 3.4.19.1. CAS No. 73562-30-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4082; acylaminoacyl-peptidase; EC 3.4.19.1; 73562-30-8; acylamino-acid-releasing enzyme; N-acylpeptide hydrolase; N-formylmethionine (fMet) aminopeptidase; α-N-acylpeptide hydrolase. Cat No: EXWM-4082. | |
| Adamantanine | Adamantanine (2-Aminoadamantane-2-carboxylic acid) inhibits the transport of methionine ( K i is 0.76 mM) and leucine into Ehrlich ascites carcinoma cells. Adamantanine inhibits proliferation of P388 lymphocytic leukemia cells with an IC 50 of >1 mM. Adamantanine inhibits the leucine aminopeptidase with an I/S 0.5 of 10.5 [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 2-Aminoadamantane-2-carboxylic acid. CAS No. 42381-05-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121123. | |
| Ala-Ala-OMe HCl | Substrate for dipeptidyl aminopeptidase I (cathepsin C). Synonyms: L-Alanyl-L-alanine methyl ester hydrochloride. Grades: ≥ 98% (TLC). CAS No. 41036-19-5. Molecular formula: C7H14N2O3·HCl. Mole weight: 210.66. | |
| Amastatin hydrochloride | Amastatin, also known as 3-amino-2-hydroxy-5-methylhexanoyl-L-valyl-L-valyl-L-aspartic acid, is a naturally occurring, competitive and reversible aminopeptidase inhibitor. Amastatin has originally been isolated from the culture filtrate of Streptomyces sp. ME98-M3 and is a competitive inhibitor of human serum aminopeptidase A (Ki = 1.1 · 10?? M) and of pig kidney leucine aminopeptidase (Ki = 1.6 · 10?? M). Amastatin hydrochloride has been shown to slightly decrease the conversion of angiontensin II to angiotensin III, but significantly increases the potency of angiotensin III and des(Asp1)angiotensin I. Synonyms: BIMI-1803; J-000280; ZX-AFC000547; Amastatin HCl. Grades: ≥95%. CAS No. 100938-10-1. Molecular formula: C21H39ClN4O8. Mole weight: 511.01. | |
| Amastatin hydrochloride | Amastatin hydrochloride is a slow, tight binding, competitive aminopeptidase (AP) inhibitor with K i values of 0.26 nM, 30 nM, 52 nM for Aeromonas aminopeptidase, cytosolic leucine aminopeptidase, microsomal aminopeptidase [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 100938-10-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-115194. | |
| Angiotensin III (human, mouse) | Angiotensin III (Ang III) is generated from Ang II by APA (and subsequently degraded by aminopeptidase N), and that central Ang III seems to play a key-role in vasopressin release and BP control. Angiotensin III, human, mouse is a heptapeptide agonist, which acts as an endogenous angiotensin type 2 receptor (AT2R) agonist. The IC50 values for AT2R is 0.648 nM and the IC50 values for AT1R is 21.1 nM. The biologically active COOH-terminal heptapeptide angiotensin III is bound more tightly than angiotensin II. Synonyms: H-Arg-Val-Tyr-Ile-His-Pro-Phe-OH; L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-phenylalanine; Ang III; Angiotensin III; 5-Ile-angiotensin III; 1-Desaspartyl-5-isoleucine angiotensin II; Des-asp(1)-(Ile(5))-angiotensin II; N5-(Diaminomethylene)-L-ornithyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-phenylalanine; 2-8-angiotensin II, 5-L-isoleucine-. Grades: ≥95%. CAS No. 13602-53-4. Molecular formula: C46H66N12O9. Mole weight: 931.09. | |
| ARM1 | ARM1 (4BSA) is a potent aminopeptidase and epoxide hydrolase inhibitor. ARM1 shows aminopeptidase inhibitory activity with an IC 50 7.61 μM and epoxide hydrolase inhibitory activity with an IC 50 12.4 μM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 4BSA. CAS No. 68729-05-5. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-W027340. | |
| ARM1 hydrobromide | ARM1 hydrobromide is a novel Leukotriene A4 hydrolase/aminopeptidase (LTA4H) inhibitor (IC50 value of ~0.5 μM in human neutrophils, and Ki value of 2.3 μM for purified LTA4H) that blocks the conversion of LTA4 into proinflammatory mediator LTB4, although leaving the aminopeptidase activity intact for cleavage and inactivation of Pro-Gly-Pro. Synonyms: ARM1 hydrobromide; ARM 1 hydrobromide; ARM-1 hydrobromide; 4-(4-benzylphenyl)-1,3-thiazol-2-amine hydrobromide. Grades: 99%. CAS No. 1049743-03-4. Molecular formula: C16H14N2S.HBr. Mole weight: 347.27. | |
| Arphamenine A | Arphamenine A is an enzyme inhibitor produced by Chromobacteriuin violaceum HMG361-CF4. It can inhibit the activity of aminopeptidase B, and can inhibit sarcoma 180 and IMC cancer. Synonyms: Benzenepropanoic acid, α-[(3S)-3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-, (αR)-; (αR)-α-[(3S)-3-Amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]benzenepropanoic acid; Benzenepropanoic acid, α-[3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-, [S-(R*,S*)]-; Arphamenin A. Grades: ≥95%. CAS No. 96551-81-4. Molecular formula: C16H24N4O3. Mole weight: 320.39. | |
| Arphamenine B | Arphamenine B is a specific inhibitor of aminopeptidase B, which is first isolated from bacteria. Arphamenine B shares the same properties as the aminopeptidase inhibitors bestatin and amastatin, both of which enhance the immune response. Synonyms: Benzenepropanoic acid, α-[(3S)-3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxy-, (αR)-; (αR)-α-[(3S)-3-Amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxybenzenepropanoic acid; Benzenepropanoic acid, α-[3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxy-, [S-(R*,S*)]-; Arphamenin B. Grades: 95%. CAS No. 103900-19-2. Molecular formula: C16H24N4O4. Mole weight: 336.39. | |
| Arphamenine B hemisulfate | Arphamenine B is a specific inhibitor of aminopeptidase B, which is first isolated from bacteria. Arphamenine B Hemisulfate is the hemisulfate form. Arphamenine B share the same property with aminopeptidase inhibitors bestatin and amastatin, they all enhance imune responses. Synonyms: Benzenepropanoic acid, α-[(3S)-3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxy-, (αR)-, sulfate (2:1) (salt); Benzenepropanoic acid, α-[3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxy-, monohydrochloride, [S-(R*,S*)]-, sulfate (2:1) (salt); Arphamenine B sulfate; (αR)-α-[(3S)-3-Amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxybenzenepropanoic acid, sulfate (2:1) (salt). Grades: ≥95%. CAS No. 144110-38-3. Molecular formula: C16H24N4O4·1/2H2SO4. Mole weight: 385.43. | |
| Bestatin | Bestatin is a natural, broad-spectrum, and competitive CD13 (Aminopeptidase N)/APN and leukotriene A4 hydrolase inhibitor. Bestatin has anticancer effects [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Ubenimex. CAS No. 58970-76-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0134. | |
| Bestatin | Bestatin is a specific aminopeptidase B inhibitor produced by Streptomyces olivoreticuli. Bestatin is a potent aminopeptidase-B and leukotriene (LT) A4 hydrolase inhibitor used in the treatment of acute myelocytic leukemia. It exhibits potential immunomodulatory and antitumor activities. Uses: The treatment of acute myelocytic leukemia. Synonyms: Ubenimex. Grades: >98%. CAS No. 58970-76-6. Molecular formula: C16H24N2O4. Mole weight: 308.37. | |
| Bestatin | Bestatin is "pseudo"-dipeptide isolated from Streptomyces olivreticuli in 1976. Bestatin is potent aminopeptidase B inhibitor with no carboxypeptidase activity. Bestatin acts as an immunomodulator by activation of macrophages and T-lymphocytes. Bestatin also exhibits good antitumor activity and is under clinical investigation. Group: Biochemicals. Grades: Highly Purified. CAS No. 58970-76-6. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Bestatin hydrochloride | Bestatin hydrochloride is a competitive aminopeptidase inhibitor, which is studied for use in the treatment of acute myelocytic leukemia. It has become a useful tool in elucidating the physiological role of some mammalian exopeptidases in the regulation of the immune system, in the growth of tumors and their invasion of surrounding tissues, and in the degradation of cellular proteins. Synonyms: Aminopeptidase inhibitor; leucine aminopeptidase; aminopeptidase B; NK-421. Grades: >98%. CAS No. 65391-42-6. Molecular formula: C16H24N2O4.HCl. Mole weight: 344.83. | |
| Bestatin hydrochloride | Bestatin hydrochloride is an inhibitor of CD13 (Aminopeptidase N)/APN and leukotriene A4 hydrolase , used for cancer research. Uses: Scientific research. Group: Natural products. Alternative Names: Ubenimex hydrochloride. CAS No. 65391-42-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0134A. | |
| Bestatin trifluoroacetate | Bestatin, also known as Ubenimex (INN), is a competitive protease inhibitor. It is an inhibitor of aminopeptidase B, leukotriene A4 hydrolase, aminopeptidase N. It is being studied for use in the treatment of acute myelocytic leukemia. Bestatin can be administered, with low toxicity, to cultured cells, intact animals and humans. It has become a useful tool in elucidating the physiological role of some mammalian exopeptidases in the regulation of the immune system, in the growth of tumors and their invasion of surrounding tissues, and in the degradation of cellular proteins. Synonyms: Ubenimex trifluoroacetate. Grades: >98%. CAS No. 223763-80-2. Molecular formula: C18H25F3N2O6. Mole weight: 422.4. | |
| bleomycin hydrolase | The molecule is a homohexamer in which the monomers have a papain-like tertiary structure (in peptidase family C1). The active sites are on the walls of a central channel through the molecule, and access of substrate molecules to them is obstructed by this and by the C-terminus of each polypeptide chain. Bleomycin can scarcely be the natural substrate, and there are reports of limited endopeptidase activity. Known from bacteria as well as eukaryotic organisms. Hydrolase H from chicken muscle has many similarities to bleomycin hydrolase, but hydrolyses Ph-CO-Arg-2-naphthylamine as well as aminopeptidase substrates. Group: Enzymes. Synonyms: aminopeptidase C (Lactococcus lactis). Enzyme Commission Number: EC 3.4.22.40. CAS No. 53096-17-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4215; bleomycin hydrolase; EC 3.4.22.40; 53096-17-6; aminopeptidase C (Lactococcus lactis). Cat No: EXWM-4215. | |
| Boc-(S)-2-amino-3-hydroxy-3-methylbutanoic acid | Boc-(S)-2-amino-3-hydroxy-3-methylbutanoic acid is used as a reagent in the synthesis of metabolites of PPI-2458, which is a selective, irreversible inhibitor of methionine aminopeptidase-2 (MetAP2). N-Boc-3-hydroxy-L-valine is also used in the preparation of Boceprevir, an NS3 serine protease inhibitor of hepatitis C virus for the treatment of HCV infection. Synonyms: Boc-L-Ser(3,3-dimethyl)-OH; (S)-Boc-β,β-dimethyl-serine; N-[(1,1-Dimethylethoxy)carbonyl]-3-methyl-L-threonine; N-[(1,1-Dimethylethoxy)carbonyl]-3-hydroxy-L-valine; (S)-2-(tert-Butoxycarbonylamino)-3-hydroxy-3-methylbutanoic Acid; n-boc-(s)-2-amino-3-hydroxy-3-methylbutanoic acid; (S)-2-N-Boc-amino-3-hydroxy-3-methylbutyric acid; (S)-N-Boc-2-Amino-3-hydroxy-3-methylbutanoic acid; L-Valine, N-[(1,1-dimethylethoxy)carbonyl]-3-hydroxy-; L-Threonine, N-[(1,1-dimethylethoxy)carbonyl]-3-methyl-; N-(tert-butoxycarbonyl)-3-hydroxy-L-valine; (2S)-2-(N-tert-Butoxycarbonyl)amino-3-hydroxy-3-methylbutanoic acid; N-boc-3-hydroxy-L-valine. Grades: ≥ 98% (Assay). CAS No. 102507-13-1. Molecular formula: C10H19NO5. Mole weight: 233.26. | |
| Bradykinin (2-9) | Bradykinin (2-9) is an amino-truncated Bradykinin peptide. Bradykinin (2-9) is a metabolite of Bradykinin, cleaved by Aminopeptidase P. Uses: Scientific research. Group: Peptides. Alternative Names: Des-Arg1-bradykinin. CAS No. 16875-11-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1490. | |
| Bradykinin 2-9 | Bradykinin 2-9, a metabolite of Bradykinin, is an amino-truncated Bradykinin peptide cleaved by Aminopeptidase P. Synonyms: Des-Arg1-bradykinin; H-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH; L-prolyl-L-prolyl-glycyl-L-phenylalanyl-L-seryl-L-prolyl-L-phenylalanyl-L-arginine; Bradykinin fragment 2-9; 2-9-Bradykinin. Grades: ≥95%. CAS No. 16875-11-9. Molecular formula: C44H61N11O10. Mole weight: 904.02. | |
| Bu-2743E | Bu-2743E is a leucine aminopeptidase (LAP) inhibitor originally isolated from Bacillus circulans J725-B93. It inhibits the LAP with an IC50 of 0.51 μg/mL. Synonyms: (2,3-Dihydroxybenzoyl)-L-alanyl-L-threonine. CAS No. 88167-28-6. Molecular formula: C14H18N2O7. Mole weight: 326.30. | |
| DG-051 | DG-051 is a potent, orally bioavailable leukotriene A4 hydrolase (LTA4H) inhibitor, the enzyme that catalyzes the rate-determining step in the synthesis of LTB4. HDG-051 does not show any inhibitory activity against a panel of more than 50 additional aminopeptidases, ion channels, or HERG. Synonyms: UNII-28B7Y5Y8EF; 28B7Y5Y8EF; 4- ( (S) -2- ( (4- (4-chlorophenoxy) phenoxy) Methyl) pyrrolidin-1-yl) butanoic acid hydrochloride. Grades: ≥98%. CAS No. 929915-58-2. Molecular formula: C21H24ClNO4·HCl. Mole weight: 426.3. | |
| dipeptidyl-peptidase I | A Cl--dependent, lysosomal cysteine-type peptidase maximally active at acidic pH. Also polymerizes dipeptide amides, arylamides and esters at neutral pH. In peptidase family C1 (papain family). Group: Enzymes. Synonyms: cathepsin C; dipeptidyl aminopeptidase I; dipeptidyl transferase; cathepsin C; dipeptidyl transferase; dipeptide arylamidase I; DAP I. Enzyme Commission Number: EC 3.4.14.1. CAS No. 9032-68-2. CTSC. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4043; dipeptidyl-peptidase I; EC 3.4.14.1; 9032-68-2; cathepsin C; dipeptidyl aminopeptidase I; dipeptidyl transferase; cathepsin C; dipeptidyl transferase; dipeptide arylamidase I; DAP I. Cat No: EXWM-4043. | |
| dipeptidyl-peptidase II | A lysosomal serine-type peptidase in family S28 (Pro-X carboxypeptidase family); maximally active at acidic pH. Group: Enzymes. Synonyms: dipeptidyl aminopeptidase II; dipeptidyl arylamidase II; carboxytripeptidase; dipeptidyl peptidase II; dipeptidyl arylamidase II; DAP II; dipeptidyl(amino)peptidase II; dipeptidylarylamidase. Enzyme Commission Number: EC 3.4.14.2. CAS No. 76199-23-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4048; dipeptidyl-peptidase II; EC 3.4.14.2; 76199-23-0; dipeptidyl aminopeptidase II; dipeptidyl arylamidase II; carboxytripeptidase; dipeptidyl peptidase II; dipeptidyl arylamidase II; DAP II; dipeptidyl(amino)peptidase II; dipeptidylarylamidase. Cat No: EXWM-4048. | |
| dipeptidyl-peptidase III | A cytosolic peptidase that is active at neutral pH. It has broad activity on peptides, although it is highly selective for Arg-Arg-2-naphthylamide, at pH 9.2. Active in the hydrolysis of enkephalins. A metallopeptidase, the type example of peptidase family M49. Group: Enzymes. Synonyms: dipeptidyl aminopeptidase III; dipeptidyl arylamidase III; enkephalinase B; red cell angiotensinase. Enzyme Commission Number: EC 3.4.14.4. CAS No. 77464-87-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4049; dipeptidyl-peptidase III; EC 3.4.14.4; 77464-87-0; dipeptidyl aminopeptidase III; dipeptidyl arylamidase III; enkephalinase B; red cell angiotensinase. Cat No: EXWM-4049. | |
| dipeptidyl-peptidase IV | A homodimer. An integral protein of the plasma membrane of lymphocytes and other mammalian cells, in peptidase family S9 (prolyl oligopeptidase family). The reaction is similar to that of the unrelated EC 3.4.14.11 Xaa-Pro dipeptidyl-peptidase of lactococci. Group: Enzymes. Synonyms: dipeptidyl aminopeptidase IV; Xaa-Pro-dipeptidyl-aminopeptidase; Gly-Pro naphthylamidase; postproline dipeptidyl aminopeptidase IV; lymphocyte antigen CD26; glycoprotein GP110; dipeptidyl peptidase IV; glycylproline aminopeptidase; glycylproline aminopeptida. Enzyme Commission Number: EC 3.4.14.5. CAS No. 54249-88-6. DPP IV. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4050; dipeptidyl-peptidase IV; EC 3.4.14.5; 54249-88-6; dipeptidyl aminopeptidase IV; Xaa-Pro-dipeptidyl-aminopeptidase; Gly-Pro naphthylamidase; postproline dipeptidyl aminopeptidase IV; lymphocyte antigen CD26; glycoprotein GP110; dipeptidyl peptidase IV; glycylproline aminopeptidase; glycylproline aminopeptidase; X-prolyl dipeptidyl aminopeptidase; pep X; leukocyte antigen CD26; glycylprolyl dipeptidylaminopeptidase; dipeptidyl-peptide hydrolase; glycylprolyl aminopeptidase; dipeptidyl-aminopeptidase IV; DPP IV/CD26; amino acyl-prolyl dipeptidyl aminopeptidase; T cell triggering molecule Tp103; X-PDAP. Cat No: EXWM-4050. | |
| Dipeptidyl Peptidase IV from Human, Recombinant | Native DPPIV is a ubiquitous type II transmembrane glycoprotein and a serine protease of the S9 prolyl-oligopeptidase family. In vivo, it is synthesized with a signal peptide, which functions as the membrane anchoring domain. There is an 88% sequence homology between the human and porcine kidney enzymes. Both exist as homodimers with a subunit molecular weight of ~30 kDa. The high mannose 100 kDa DPPIV precursor is processed in the Golgi to yield a 124 kDa heavily N-and O-linked mature glycoprotein. It is then sorted to the apical membrane through the concerted action of both N-and O-linked glycans and its association with lipid microdomains. The porcine enzyme contai...zyme from creative enzymes has been used to study the lc-ms (liquid chromatography-mass spectrometry) based assay method for dpp-iv inhibitor screening and substrate discovery. Group: Enzymes. Synonyms: EC 3.4.14.5; 54249-88-6; DPPIV; DPP4; dipeptidyl aminopeptidase IV; Xaa-Pro-dipeptidyl-aminopeptidase; Gly-Pro naphthylamidase; postproline dipeptidyl aminopeptidase IV; lymphocyte antigen CD26; glycoprotein GP110; dipeptidyl peptidase IV; glycylproline aminopeptidase; glycylproline aminopeptidase; X-prolyl dipeptidyl aminopeptidase; pep X; leukocyte antigen CD26; glycylprolyl dipeptidylaminopeptidase; dipeptidyl-peptide hydrolase; glycylprolyl aminopeptidase; dipeptidy | |
| Dipeptidyl Peptidase VII from Human, Recombinant | DPP7 is essential for maintaining lymphocytes and fibroblasts in G (0). The inhibition of DPP7 results in apoptosis, which is mediated by the induction of c-Myc and p53. DPP7 has strong sequence homology with prolylcarboxypeptidase and is active at both acidic and neutral pH. Contains amino acids 29 to end with a c-terminal his tag, mw=89.1 kda. Applications: Dipeptidyl peptidase vii (dpp7), also known as dpp2 or quiescent cell proline dipeptidase, is a post-proline cleaving aminopeptidase that is expressed in quiescent lymph ocytes. dpp7 is used to study the regulation of cell quiescence. like dpp4, dpp7 may be useful in diabetes and vascular disease research. Group: Enzymes. Synonyms: EC 3.4.14.-; DPP7; Quiescent cell proline dipeptidase; Dipeptidyl Peptidase VII; DPP VII. Enzyme Commission Number: EC 3.4.14.-. DPP VII. Mole weight: 89.1 kDa. Storage: -70°C. Form: Supplied as a solution in 25 mM Tris-HCl, pH 8.0, 130 mM NaCl, 0.05% Tween-20, 10% glycerol. Source: Sf9 cells. Species: Human. EC 3.4.14.-; DPP7; Quiescent cell proline dipeptidase; Dipeptidyl Peptidase VII; DPP VII. Cat No: NATE-0206. | |
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