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| Product | Description | |
|---|---|---|
| Alamethicin | Alamethicin is a linear 20-amino acid antibiotic , which can induce voltage-gated conductance in model and cell membranes. Alamethicin exhibits antimicrobial activity against Gram-positive bacteria, but not Gram-negative bacteria. Alamethicin can form an amphipathic α-helical structure in biological membranes [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 27061-78-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N6708. |  |
| Aminopeptidase N Ligand (CD13), NGR peptide | It is a peptide with NGR (Asn-Gly-Arg) motif, which has a disulfide bridge linking cys1 and cys5, and is known to have antimicrobial properties in addition to the presence of KLA sequences. The peptide binds to CD13 on tumor cells and shows strong cytotoxicity and activity against tumor cells. This peptide shows dose-dependent antiproliferation against tumor cells and induces cell cylce arrest at G2/M phases and apoptosis of the tumor cells. Peptides containing the NGR motif are useful in the delivery of cytotoxic drugs, pro-apoptotic peptides, and tumor necrosis factor (TNF) into tumor vasculature. Synonyms: H-Cys-Asn-Gly-Arg-Cys-Gly-OH (Disulfide bridge: Cys1-Cys5); L-cysteinyl-L-asparagyl-glycyl-L-arginyl-L-cysteinyl-glycine (1->5)-disulfide; N-{[(4R,5E,7S,8E,11E,13S,14E,16R)-16-Amino-7-(3-carbamimidamidopropyl)-6,9,12,15-tetrahydroxy-13-(2-hydroxy-2-iminoethyl)-1,2-dithia-5,8,11,14-tetraazacycloheptadeca-5,8,11,14-tetraen-4-yl](hydroxy)methylene}glycine. Grade: ≥95%. Molecular formula: C20H34N10O8S2. Mole weight: 606.67. |  |
| Antimicrobial peptide CHP1 | Antimicrobial peptide CHP1 is an antimicrobial peptide found in Gallus gallus (Chicken, avian heterophil granules). It has antibacterial activity. Synonyms: Chicken heterophil peptides 1; Gly-Arg-Lys-Ser-Asp-Cys-Phe-Arg-Lys-Ser-Gly-Phe-Cys-Ala-Phe-Leu-Lys-Cys-Pro-Ser-Leu-Thr-Leu-Ile-Ser-Gly-Lys-Cys-Ser-Arg-Phe-Tyr-Leu-Cys-Cys-Lys-Arg-Ile-Arg (Disulfide bridge: Cys6-Cys28, Cys13-Cys34, Cys18-Cys35); CHP1. Grade: >85%. Molecular formula: C196H315N59O49S6. Mole weight: 4474.40. | |
| Bacteriocin | Bacteriocin is an antimicrobial peptide produced by Rhizobium leguminosarum bv. Viciae. It has antibacterial activity. Uses: Bacteriocins are a class of antimicrobial peptides or proteins produced by various bacteria that exhibit potent antimicrobial activity against closely related bacterial species. they are considered promising alternatives to conventional antibiotics due to their narrow spectrum of activity, strong target specificity, and low level of bacterial resistance development. the application of bacteriocins. Synonyms: Ala-Ser-Ile-Leu-Thr-Asn-Ala-Ser. Grade: 96%. Molecular formula: C32H57N9O13. Mole weight: 775.86. | |
| Bacteriocin microcin B17 | Bacteriocin microcin B17 is an antimicrobial peptide produced by Escherichia coli. It has antimicrobial activity. MccB17 was the first compound discovered from the Thiazole/Oxazole-Modified Microcins (TOMMs) family and the Linear Azole-containing peptides (LAPs). These ribosomal peptides are post-translationally modified to convert serine and cysteine residues into oxazole and thiazole rings. Synonyms: mcbA; MccB17. Grade: >98%. | |
| Brilacidin HCl | Brilacidin, also known as PMX30063, is an arylamide foldamer designed to replicate the amphiphilic properties of antimicrobial peptides while solving the problems encountered by peptide-based antimicrobials. Brilacidin, a broad-spectrum antibiotic, has potent Gram positive activity and Gram negative coverage, and is highly effective in treating the 'superbug' methicillin-resistant Staphylococcus aureus (MRSA). Brilacidin has low cytotoxicity against mammalian cells selectively targeting bacteria, directly and rapidly disrupting their membranes, resulting in the bacteria's death. Due to this unique mechanism of action (mimicking the host's natural immune response, proven to be successful in fighting off infections over millions of years of evolution), bacterial antibiotic resistance is less likely to develop. Uses: Designed for use in research and industrial production. Additional or Alternative Names: PMX30063; PMX-30063; PMX 30063; Brilacidin; Brilacidin HCl; Brilacidin tetrahydrochloride. Product Category: Others. Appearance: Solid powder. CAS No. 1224095-99-1. Molecular formula: C40H54Cl4F6N14O6. Mole weight: 1082.75. Purity: >98%. IUPACName: N4,N6-bis(3-(5-guanidinopentanamido)-2-(((R)-pyrrolidin-3-yl)oxy)-5-(trifluoromethyl)phenyl)pyrimidine-4,6-dicarboxamide tetrahydrochloride. Canonical SMILES: O=C(C1=NC=NC(C(NC2=CC(C(F)(F)F)=CC(NC(CCCCNC(N)=N)=O)=C2O[C@H]3CNCC3)=O)=C1)NC4=CC(C(F)(F)F)=CC(NC(CCCCNC(N)=N)=O)=C4O[C@H] |  |
| BTL | BTL was isolated from Bacillus subtilis B-TL2. BTL shows relatively low identity to other antimicrobial peptides from bacteria. The peptide exhibited strong inhibitory activity against mycelial growth of Bipolaris maydis, Alternaria brassicae, Aspergillus niger, Cercospora personata. | |
| Buforin-1 | The source of Buforin-1 is Bufo gargarizans. Buforin I is generated from histone H2A by pepsin-directed proteolysis in the cytoplasm of gastric gland cells. After secretion into the gastric lumen, buforin I remains adhered to the mucous biofilm that lines the stomach, thus providing a protective antimicrobial coat. Buforins also are known to possess anti-endotoxin and anticancer activities, thus making these peptides attractive reagents for pharmaceutical applications. | |
| Buforin-2 | Buforin II is a highly potent antimicrobial peptide which was derived from buforin I, a peptide isolated from the stomach of the Bufo gargarizans. Buforin II is an α-helical antimicrobial peptide, however it has far stronger antimicrobial activity against a broad spectrum of microorganisms compared with other α-helical antimicrobial peptides. Grade: >95% by HPLC. Mole weight: 2434.85. | |
| Caerulein precursor-related fragment Ea | The source of Caerulein precursor-related fragment Ea is Rana esculenta. This peptide has no sequence similarity with antimicrobial peptides isolated from other species of ranid frogs. It potently and selectively inhibits the growth of the Gram-positive bacterium Escherichia coli (minimal inhibitory concentration (MIC<5 microM)). Synonyms: CPRF-Ea. | |
| Caerulein precursor-related fragment Eb | The source of Caerulein precursor-related fragment Eb is Rana esculenta. This peptide has no sequence similarity with antimicrobial peptides isolated from other species of ranid frogs. It potently and selectively inhibits the growth of the Gram-positive bacterium Escherichia coli (minimal inhibitory concentration (MIC<5 microM)). Synonyms: CPRF-Eb. | |
| Caerulein precursor-related fragment Ec | The source of Caerulein precursor-related fragment Ec is Rana esculenta. This peptide has no sequence similarity with antimicrobial peptides isolated from other species of ranid frogs. It potently and selectively inhibits the growth of the Gram-positive bacterium Escherichia coli (minimal inhibitory concentration (MIC<5 microM)). Synonyms: CPRF-Ec. | |
| CATH-2 (chicken) | CATH-2 (chicken) is one of the four cathelicidins found in chickens and has immunomodulatory abilities. Cathelicidin is a family of host defense peptides (HDPs) that play an important role in innate immune responses. CATH-2 shows strong antimicrobial activity against many different pathogens, including Gram-positive, Gram-negative bacteria and fungi. Synonyms: CAMP; CATH2; CATHL2; CMAP27; cathelicidin-2 [Gallus gallus (chicken)]; cathelicidin antimicrobial peptide; fowlicidin-2; myeloid antimicrobial peptide 27; H-Arg-Phe-Gly-Arg-Phe-Leu-Arg-Lys-Ile-Arg-Arg-Phe-Arg-Pro-Lys-Val-Thr-Ile-Thr-Ile-Gln-Gly-Ser-Ala-Arg-Phe-NH2; Chicken cathelicidin-2. Grade: >95% by HPLC. Molecular formula: C147H245N51O30. Mole weight: 3206.90. | |
| Cathelicidin antimicrobial peptide | The source of Cathelicidin antimicrobial peptide is Bos taurus. Cathelicidins (CATHLs) are small, cationic antimicrobial peptides. Beyond their wide spectrum of antimicrobial activity, these peptides play important roles in wound repair, chemotactic activity, and apoptosis. | |
| Cecropin A | Cecropin A is a linear 37-residue antimicrobial polypeptide, with anticancer and anti-inflammatory activity. Uses: Scientific research. Group: Peptides. CAS No. 80451-04-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1539. | |
| Cecropin A (1-7)-Melittin A (2-9) | Cecropin A (1-7)-Melittin A (2-9) is an antimicrobial peptide with antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative aerobic bacteria, as well as antimalarial activity, without the adverse hemolytic properties of bee venom peptides [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Oct-CA(1-7)M(2-9). CAS No. 157606-25-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3914. | |
| Cecropin A (1-7)-Melittin A (2-9) amide | Cecropin A (1-7)-Melittin A (2-9) amide, a synthetic hybrid peptide consisting of parts of the naturally occurring antibiotic peptides cecropin A and melittin, exhibits better antimicrobial activity than the native molecules, but lacks the hemolytic properties of melittin. Its antimicrobial activity is not limited to aerobic microorganisms, but also includes several gram-negative and gram-positive anaerobic microorganisms. With its identified broad-spectrum antibiotic activity, it may represent an effective alternative to ciprofloxacin in the treatment of anthrax infections. Synonyms: CAMEL0; H-Lys-Trp-Lys-Leu-Phe-Lys-Lys-Ile-Gly-Ala-Val-Leu-Lys-Val-Leu-NH2; L-lysyl-L-tryptophyl-L-lysyl-L-leucyl-L-phenylalanyl-L-lysyl-L-lysyl-L-isoleucyl-glycyl-L-alanyl-L-valyl-L-leucyl-L-lysyl-L-valyl-L-leucinamide. Grade: ≥95%. CAS No. 157606-25-2. Molecular formula: C89H152N22O15. Mole weight: 1770.33. | |
| Cecropin B | Cecropin B has high level of antimicrobial activity and is considered as a valuable peptide antibiotic. Uses: Scientific research. Group: Peptides. CAS No. 80451-05-4. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-P0092. | |
| Clarithromycin | It is produced by the strain of erythromycin. Clarithromycin, a CYP3A4 inhibitor, is a macrolide antibiotic used to treat pharyngitis, tonsillitis, acute maxillary sinusitis, acute bacterial exacerbation of chronic bronchitis, pneumonia, skin and skin structure infections. It prevents bacteria from growing by interfering with their protein synthesis and binds to the subunit 50S of the bacterial ribosome and thus inhibits the translation of peptides. It has similar antimicrobial spectrum as erythromycin, but is more effective against certain Gram-negative bacteria, particularly Legionella pneumophila. It also has bactericidal effect on certain strains, such as Haemophilus influenzae, Streptococcus pneumoniae and Neisseria gonorrhoeae. Uses: Anti-bacterial agents. Synonyms: Biaxin; 6-O-Methylerythromycin; Klaricid; Abbott-56268; 6-O-Methylerythromycin A; A 56268; Abbott 56268; Antibiotic A 56268; Antibiotic TE 31; Clamicin; Claric; Claridar; Claris; Claritek; Clarith; Clarithro; Clathromycin; Crixan; CRIXAN OD; Fascar; Fromilid; Kelamycin; Klabax; Klacid; Klaribac; Klarimix; Klarithran MR; Macladin; Naxy; TE 031; Veclam; Zeclar. Grade: >98%. CAS No. 81103-11-9. Molecular formula: C38H69NO13. Mole weight: 747.95. | |
| Cn-AMP3 | Cn-AMP3 is from Cocos nucifera. It has antimicrobial activity against Gram-positive bacteria B.subtilis (MIC=257 μg/ml) and S.aureus (MIC=274 μg/ml), and against Gram-negative bacteria E.coli (MIC=302 μg/ml) and P.aeruginosa (MIC=259 μg/ml). The activity of this series of peptides is Cn-AMP1 > Cn-AMP2 > Cn-AMP3. | |
| CRAMP (mouse) | CRAMP (mouse) is an antimicrobial peptide. CRAMP (mouse) can be used for the research of biofilm-associated infections [1]. Uses: Scientific research. Group: Peptides. CAS No. 376364-36-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P4855. | |
| Cyclo(L-Trp-L-Trp) | Cyclo(L-Trp-L-Trp) is an antibiotic, and shows antimicrobial activity. Cyclo(L-Trp-L-Trp) can inhibit A. baumannii , as well as Candida albicans , Bacillus subtilis , Micrococcus luteus , Saccharomyces cerevisiae , Aspergillus niger , Staphylococcus aureus. Cyclo(L-Trp-L-Trp) can be used in microbial infection research [1]. Uses: Scientific research. Group: Peptides. CAS No. 20829-55-4. Pack Sizes: 50 mg; 100 mg. Product ID: HY-P2124. | |
| Cytolysin | Cytolysin belongs to class I bacteriocins in lantibiotics. Cytolysin is isolated from Enterococcus faecalis and has antibacterial activity. Uses: Cytolysins, also known as cytotoxins, are antimicrobial peptides that play a key role in the body's defense against microbial invaders. these peptides are produced by a variety of organisms, including bacteria, fungi, and animals, and have been extensively studied for their potential applications in medicine, biotechnology, and food preservation. cytolysins have a variety of applications in variou. Synonyms: Thr-Thr-Pro-Ala-Cys-Phe-Thr-Ile-Gly-Leu-Gly-Val-Gly-Ala-Leu-Phe-Ser-Ala-Lys-Phe-Cys. Grade: 95.8%. | |
| D-allo-Isoleucine | D-allo-Isoleucine. Uses: D-allo-isoleucine is used in the synthesis of a conjugate of epi-jasmonic acid and various antimicrobial peptides. Additional or Alternative Names: (2R,3S)-2-Amino-3-methylpentanoic acid. Product Category: Amino Acids. CAS No. 1509-35-9. Molecular formula: CH3CH2CH(CH3)CH(NH2)CO2H. Mole weight: 131.17. Canonical SMILES: CC[C@H](C)[C@@H](N)C(O)=O. ECNumber: 216-143-9. Product ID: ACM1509359. Alfa Chemistry ISO 9001:2015 Certified. Categories: D-Alloisoleucine. | |
| Dermaseptin | Dermaseptin, a peptide isolated from frog skin, exhibits potent antimicrobial activity against bacteria, fungi, and protozoa at micromolar concentration [1]. Uses: Scientific research. Group: Peptides. CAS No. 136212-91-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0263. | |
| Dermaseptin TFA | Dermaseptin TFA, a peptide isolated from frog skin, exhibits potent antimicrobial activity against bacteria, fungi, and protozoa at micromolar concentration [1]. Uses: Scientific research. Group: Peptides. CAS No. 646451-06-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P0263A. | |
| Fmoc-Arg(Me)2-OH (asymmetrical) | Fmoc-Arg(Me)2-OH is a peptide derivative that consists of two methylated arginines (Me) with an N-terminal Fluorenylmethyloxycarbonyl (Fmoc) group. The Fmoc group is a protective group that is commonly used in peptide synthesis to protect the N-terminus of amino acids from unwanted reactions. Arginine is an amino acid that plays an essential role in protein synthesis, and its importance in biological functions has been well established. The introduction of the Me modification to the arginine molecule has led to significant developments in peptide synthesis. Uses: Fmoc-arg(me)2-oh has various applications in scientific research. this compound is commonly used in peptide synthesis and has been found to be useful in the preparation of various peptides such as antimicrobial peptides and peptide hormones. fmoc-arg(me)2-oh is also used as a substrate in enzymatic assays and as a modifier in protein labeling. Product Category: Amino Acids. CAS No. 268564-10-9. Molecular formula: C23H28N4O4. Mole weight: 424.5. Purity: Peak Area by HPLC ≥95%. IUPACName: (2S)-5-[[amino(dimethylamino)methylidene]amino]-2-(9H-fluoren-9-ylmethoxycarbonylamino)pentanoic acid. Canonical SMILES: CN(C)C(=NCCCC(C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13)N. Density: 1.28 g/mL at 20 °C(lit.). Product ID: ACM268564109-1. Alfa Chemistry ISO 9001:2015 Certified. Categories: Fmoc-ADMA hydrochloride salt. | |
| Fmoc-Dha-OH | Fmoc-Dha-OH, a pivotal intermediate, is used for synthesizing a plethora of biologically active compounds encompassing antimicrobial peptides, dipeptidyl peptidase IV inhibitors, and enzyme inhibitors. Researchers have employed it to fabricate Fmoc-Dha-OH-derived peptidomimetics manifested by the impeding activity against a myriad of cancer cell lines. The said compound holds sheer potential for the design and development of novel pharmaceutical agents targeting numerous diseases. Synonyms: Fmoc-dehydro-Ala-OH; N-(9H-Fluorene-9-ylmethoxycarbonyl)-2,3-didehydro-L-alanine; 2-(((9H-fluoren-9-yl)methoxy)carbonylamino)acrylic acid. CAS No. 261522-33-2. Molecular formula: C18H15NO4. Mole weight: 309.3. | |
| Fmoc-D-Thr[PO(OBzl)-OH]-OH | Fmoc-O-(benzylphospho)-L-threonine is a phosphopeptide derivative that is used in the synthesis of proteins and peptides. The compound is formed by attaching a benzylphosphonic acid group to the hydroxyl group of the threonine residue. This modification can enhance the stability and specificity of the peptide or protein towards its target. The Fmoc (fluorenylmethoxycarbonyl) group is a common protecting group used in peptide synthesis to prevent unwanted chemical reactions during the coupling of amino acids. Uses: Fmoc-o-(benzylphospho)-l-threonine has been widely used in scientific experiments to improve the stability and specificity of peptides and proteins towards their targets. the compound has been used in the synthesis of various bioactive peptides, such as antimicrobial peptides, and has shown potential for various biomedical applications. Additional or Alternative Names: Fmoc-Thr(PO(OBzl)OH)-OH, N-α-Fmoc-O-benzyl-L-phosphothreonine, Fmoc-O-(benzylphospho)-L-threonine. Product Category: Amino Acids. CAS No. 175291-56-2. Molecular formula: C26H26NO8P. Mole weight: 511.5. IUPACName: (2S,3R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-[hydroxy(phenylmethoxy)phosphoryl]oxybutanoic acid. Canonical SMILES: CC(C(C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13)OP(=O)(O)OCC4=CC=CC=C4. Density: 1.4±0.1 g/cm3. Product ID: ACM175291562-1. Alfa Chemistry ISO 9001:2015 Certified. | |
| Fmoc-homopropargylglycine | Building block for the introduction by Fmoc SPPS. of an amino acid bearing an alkyne side chain. Such derivatives are useful tools for the synthesis of cyclic peptides by an alkyne-alkyne Glaser coupling, involving Cu(OAc)2/pyridine and heating to 60 °Cusing microwaves. Uses: Fmoc-hpg-oh has a wide range of applications in scientific research. it can be used to synthesize peptides with desirable biological properties such as antimicrobial activity, anticancer activity, and enzyme inhibitory activity. these peptides can be used in drug discovery and development, as well as in the treatment of a wide range of diseases. Additional or Alternative Names: Fmoc-homopropargylglycine. Product Category: Amino Acids. CAS No. 942518-21-0. Molecular formula: C21H19NO4. Mole weight: 349.38. IUPACName: (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)hex-5-ynoic acid. Canonical SMILES: C#CCCC(C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13. Density: 1.265±0.06 g/mL. Product ID: ACM942518210. Alfa Chemistry ISO 9001:2015 Certified. | |
| Fmoc-L-beta -homoalanine | Fmoc-L-beta-homoalanine is a modified form of the amino acid beta-homoalanine, which is naturally found in certain fungi, algae, and invertebrates. It is primarily used as a building block for solid-phase peptide synthesis (SPPS) due to its ability to form stable amide bonds. Fmoc-L-beta-homoalanine is also a useful tool in the study of peptide-protein interactions, as it can serve as a non-natural amino acid substitute. Uses: Fmoc-l-beta-homoalanine has a range of applications in scientific experiments, particularly in the fields of peptide synthesis and drug discovery. it can be used as a building block for the synthesis of various peptides, including antimicrobial peptides and peptidomimetics. it has also been investigated as a potential drug candidate for various diseases, including cancer and infectious diseases. Additional or Alternative Names: Fmoc--HoAla-OH, Fmoc-Beta-HoAla-OH, Fmoc-β-homoalanine, Fmoc-β-HomoAla-OH. Product Category: Amino Acids. CAS No. 193954-26-6. Molecular formula: C19H19NO4. Mole weight: 325.4. Purity: Peak Area by HPLC ≥95%. IUPACName: (3S)-3-(9H-fluoren-9-ylmethoxycarbonylamino)butanoic acid. Canonical SMILES: CC(CC(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13. Density: 1.255 g/cm3. Product ID: ACM193954266-1. Alfa Chemistry ISO 9001:2015 Certified. Categories: (3S)-3-({[(9H-FLUOREN-9-YL)METHOXY]CARBONYL}AMINO)BUTANOIC ACID. | |
| Gageostatin A | An antimicrobial peptide (AMP) isolated from a marine strain of bacillus subtilis. It is a linear lipopeptide composed of 7 peptides. It has shown initial bioactivity against pathogenic fungi, gram-positive and gram-negative bacteria, and cancer cell lines. Synonyms: Unk-Glu-Leu-Leu-D-Val-Asp-Leu-Leu-OH; N-[(3R)-3-Hydroxy-11-methyltridecanoyl]-L-α-glutamyl-L-leucyl-L-leucyl-D-valyl-L-α-asparagyl-L-leucyl-L-leucine. Grade: ≥90%. Molecular formula: C52H93N7O14. Mole weight: 1040.33. | |
| Gallinacin-1 alpha | Gallinacin-1 alpha is an antimicrobial peptide found in Gallus gallus (Chicken, avian heterophil granules). It has potent activity against E.coli ML-35, L.monocytogenes EGD and C.albicans. Synonyms: CHP2; Chicken heterophil peptides 2; Antimicrobial peptide CHP2; Gal-1 alpha. Grade: >85%. Molecular formula: C205H316N60O48S6. Mole weight: 4581.49. | |
| Gramicidin | Gramicidin is an antimicrobial peptide assembling as channels in membranes and increasing their permeability towards cations. Uses: Scientific research. Group: Peptides. CAS No. 1405-97-6. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-P0163. | |
| Hainanenin 1 | Hainanenins is a novel family of antimicrobial peptides with strong activity from Hainan cascade-frog, Amolops hainanensis. The results showed that hainanenin-1 possessed strong and broad-spectrum antimicrobial activities against Gram-positive, Gram-negative bacteria and fungi, including a large number of clinically isolated drug-resistant pathogenic microorganisms, and slight antioxidant activity. | |
| Hainanenin 5 | Hainanenins is a novel family of antimicrobial peptides with strong activity from Hainan cascade-frog, Amolops hainanensis. The results showed that hainanenin-5 possessed strong and broad-spectrum antimicrobial activities against Gram-positive, Gram-negative bacteria and fungi, including a large number of clinically isolated drug-resistant pathogenic microorganisms, and slight antioxidant activity. Grade: >95% by HPLC. | |
| HAP-1 | HAP-1 is a synovial-targeted transduction peptide. HAP-1 facilitates specific internalization of protein complexes into human and rabbit synovial cells. HAP-1 fused to an antimicrobial peptide, (KLAK) 2 , to generate a proapoptotic peptide DP2 [1]. Uses: Scientific research. Group: Peptides. CAS No. 329004-38-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P4096. | |
| Hepcidin-25 (human) | Hepcidin-25 (hepatic bactericidal protein), also known as LEAP-1 (liver-expressed antimicrobial peptide), is found independently in human blood ultrafiltration and urine. It is mainly expressed in liver and belongs to a new family of small vertebrate antimicrobial peptides that contain 8 cysteine residues and has obvious antibacterial and antifungal activities. Hepcidin is the main human iron regulatory hormone, which can bind to iron exporter ferroportin and induce its internalization and degradation, thus blocking iron efflux from cells. Uses: Anti-infective agents. Synonyms: LEAP-1 (human); H-Asp-Thr-His-Phe-Pro-Ile-Cys-Ile-Phe-Cys-Cys-Gly-Cys-Cys-His-Arg-Ser-Lys-Cys-Gly-Met-Cys-Cys-Lys-Thr-OH (Disulfide bridge: Cys7-Cys23, Cys10-Cys13, Cys11-Cys19, Cys14-Cys22); L-alpha-aspartyl-L-threonyl-L-histidyl-L-phenylalanyl-L-prolyl-L-isoleucyl-L-cysteinyl-L-isoleucyl-L-phenylalanyl-L-cysteinyl-L-cysteinyl-glycyl-L-cysteinyl-L-cysteinyl-L-histidyl-L-arginyl-L-seryl-L-lysyl-L-cysteinyl-glycyl-L-methionyl-L-cysteinyl-L-cysteinyl-L-lysyl-L-threonine (7->23),(10->13),(11->19),(14->22)-tetrakis(disulfide); Hepcidin Hepc25 (human); Hepcidin-25. Grade: ≥95% by HPLC. CAS No. 1356390-47-0. Molecular formula: C113H170N34O31S9. Mole weight: 2789.35. | |
| Histatin-3 TFA | Histatin-3 TFA, a 32 amino acid peptide, possesses powerful antimicrobial properties. Histatin-3 TFA behaves as a substrate for proprotein convertase 1 (PC1), being cleaved by this endoprotease primarily at a site carboxy terminal to the single Arg25 residue (HRGYR decrease SN). Histatin-3 TFA is a moderately potent, reversible and competitive inhibitor of the furin-mediated cleavage of the pentapeptide pGlu-Arg-Thr-Lys-Arg-MCA fluorogenic substrate, with an estimated inhibition constant K i of 1.98 μM [1]. Uses: Scientific research. Group: Peptides. CAS No. 112844-49-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P5272. | |
| Human β-defensin-1 | Human β-defensin-1 (HβD-1) is a cysteine-rich cationic skin-antimicrobial peptide (SAP) produced by all epithelial surfaces, but also by circulatory cells and cells of the reproductive tract. Human β-defensin-1 has antimicrobial activities against a broad-sperm bacteria [1]. Uses: Scientific research. Group: Peptides. Alternative Names: HβD-1. CAS No. 452274-53-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2315. | |
| IDR-1 | IDR-1 is an antimicrobial peptide that is active against Gram-positive and Gram-negative bacteria. IDR-1 counters infection by selective modulation of innate immunity without obvious toxicities. IDR-1 has anti-inflammatory and anti-infective properties, enhances the levels of monocyte chemokines, and attenuates pro-inflammatory cytokine release [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 940291-10-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P2320. | |
| IL-17A-17F Heterodimer Protein, Human (Biotinylated, HEK293, His-Avi) | IL-17A-17F heterodimer protein is a heterodimer of the cytokines IL-17A and IL-17F, and its biological activity is between IL-17A and IL-17F. Both IL-17A and IL-17F can induce the production of antimicrobial peptides (defensins and S100 proteins), cytokines (IL-6, G-CSF, and GM-CSF), chemokines (CXCL1, CXCL5, IL-8, CCL2, and CCL7), and matrix metalloproteinases (MMP1, MMP3, and MMP13). IL-17A-17F Heterodimer Protein, Human (Biotinylated, HEK293, His-Avi), composed of 265 amino acids (IL-17A (G24-A155) and IL-17F (R31-Q163)), is a biotinylated recombinant human IL-17A-17F heterodimer protein expressed in HEK293 cells with His tag and Avi tag. Synonyms: IL-17A; Interleukin-17A; CTLA-8; IL-17; IL-17F; IL24; ML-1; Interleukin-17F. Grade: ≥95%. Mole weight: ~16 kDa. | |
| IL-17A-17F Heterodimer Protein, Mouse (Biotinylated, HEK293, His-Avi) | IL-17A-17F heterodimer protein is a heterodimer of the cytokines IL-17A and IL-17F, and its biological activity is between IL-17A and IL-17F. Both IL-17A and IL-17F can induce the production of antimicrobial peptides (defensins and S100 proteins), cytokines (IL-6, G-CSF, and GM-CSF), chemokines (CXCL1, CXCL5, IL-8, CCL2, and CCL7), and matrix metalloproteinases (MMP1, MMP3, and MMP13). IL-17A-17F Heterodimer Protein, Mouse (Biotinylated, HEK293, His-Avi), composed of 266 amino acids (IL-17A (A26-A158) and IL-17F (R29-A161)), is a biotinylated recombinant mouse IL-17A-17F heterodimer protein expressed in HEK293 cells with His tag and Avi tag. Synonyms: IL-17A; Interleukin-17A; CTLA-8; IL-17; IL-17F; IL24; ML-1; Interleukin-17F. Grade: ≥95%. Mole weight: 22-25&27-30 kDa. | |
| IL-17A Protein, Human (Biotinylated, 132a.a, HEK293, His-Avi) | Interleukin 17 (IL-17) family is a family of pro-inflammatory cystine node cytokines consisting of IL17A, IL17B, IL17C, IL17D, IL17E, and IL17F. IL-17A is a homodimer factor that plays a key role in host defense mechanisms against many bacterial and fungal pathogens, as well as allergic and autoimmune responses. IL-17A induces the production of antimicrobial peptides (defensins and S100 proteins), cytokines (IL-6, G-CSF, and GM-CSF), chemokines (CXCL1, CXCL5, IL-8, CCL2, and CCL7), and matrix metalloproteinases (MMP1, MMP3, and MMP13). IL-17A Protein, Human (Biotinylated, 132a.a, HEK293, His-Avi), composed of 132 amino acids (G24-A155), is a biotinylated recombinant human IL-17A protein expressed in HEK293 cells with His tag and Avi tag. Synonyms: CTLA-8; IL17; IL17A; IL-17CTLA-8; Interleukin 17A. Grade: ≥95%. Mole weight: 16-30 kDa. | |
| IL-17A Protein, Mouse (Biotinylated, HEK293, His-Avi) | Interleukin 17 (IL-17) family is a family of pro-inflammatory cystine node cytokines consisting of IL17A, IL17B, IL17C, IL17D, IL17E, and IL17F. IL-17A is a homodimer factor that plays a key role in host defense mechanisms against many bacterial and fungal pathogens, as well as allergic and autoimmune responses. IL-17A induces the production of antimicrobial peptides (defensins and S100 proteins), cytokines (IL-6, G-CSF, and GM-CSF), chemokines (CXCL1, CXCL5, IL-8, CCL2, and CCL7), and matrix metalloproteinases (MMP1, MMP3, and MMP13). IL-17A Protein, Mouse (Biotinylated, HEK293, His-Avi), composed of 133 amino acids (A26-A158), is a biotinylated recombinant mouse IL-17A protein expressed in HEK293 cells with His tag and Avi tag. Synonyms: CTLA-8; IL17; IL17A; IL-17CTLA-8; Interleukin 17A. Grade: ≥95%. Mole weight: 20-28 kDa. | |
| IL-17C Protein, Human (Biotinylated, HEK293, His-Avi) | Interleukin 17 (IL-17) family is a family of pro-inflammatory cystine node cytokines consisting of IL17A, IL17B, IL17C, IL17D, IL17E, and IL17F. IL-17C is predominantly expressed by epithelial cells and is produced by cells expressing Chromogranin A (enteroendocrine cells) and mucin (goblet cells). IL-17C is an early response cytokine in bacterial pathogen defense and upregulates the expression of a variety of antimicrobial peptides, including human beta-defensin 2 (hBD2), Lipocalin 2 (LCN2), and granzyme b. IL-17C stimulates the release of cytokines (IL-1β, TNF-α, and IL-6), and is implicated in autoimmune disorders and bacterial infections. IL-17C Protein, Human (Biotinylated, HEK293, His-Avi), composed of 179 amino acids (H19-V197), is a biotinylated recombinant human IL-17C protein expressed in HEK293 cells with His tag and Avi tag. Synonyms: CX2; Cytokine CX2; IL17C; IL-17; CMGC126884; Interleukin 17C; Interleukin-17C. Grade: ≥90%. Mole weight: 24-26 kDa. | |
| IL-17F Protein, Human (Biotinylated, HEK293, His-Avi) | Interleukin 17 (IL-17) family is a family of pro-inflammatory cystine node cytokines consisting of IL17A, IL17B, IL17C, IL17D, IL17E, and IL17F. IL-17F induces the expression of a variety of pro-inflammatory cytokines and chemokines. IL-17F signaling can lead to the production of antimicrobial peptides and matrix metalloproteinases. IL-17F signaling activates the MAP kinase pathway, leading to the activation of NF-κB, MAPK-AP-1, and C/EBP. IL-17F is a proinflammatory homodimer factor associated with many diseases, including psoriasis, ankylosing spondylitis, asthma and allergic airway inflammation, intestinal inflammation, and cancer. IL-17F Protein, Human (Biotinylated, HEK293, His-Avi), composed of 133 amino acids (R31-Q163), is a biotinylated recombinant human IL-17F protein expressed in HEK293 cells with His tag and Avi tag. Synonyms: Cytokine ML-1; IL17F; IL-17F; IL24; IL-24; CANDF6; IL-17F; ML1. Grade: ≥95%. Mole weight: 23-28 kDa. | |
| IL-17F Protein, Mouse (Biotinylated, HEK293, His-Avi) | Interleukin 17 (IL-17) family is a family of pro-inflammatory cystine node cytokines consisting of IL17A, IL17B, IL17C, IL17D, IL17E, and IL17F. IL-17F induces the expression of a variety of pro-inflammatory cytokines and chemokines. IL-17F signaling can lead to the production of antimicrobial peptides and matrix metalloproteinases. IL-17F signaling activates the MAP kinase pathway, leading to the activation of NF-κB, MAPK-AP-1, and C/EBP. IL-17F is a proinflammatory homodimer factor associated with many diseases, including psoriasis, ankylosing spondylitis, asthma and allergic airway inflammation, intestinal inflammation, and cancer. IL-17F Protein, Mouse (Biotinylated, HEK293, His-Avi), composed of 133 amino acids (R29-A161), is a biotinylated recombinant mouse IL-17F protein expressed in HEK293 cells with His tag and Avi tag. Synonyms: Cytokine ML-1; IL17F; IL-17F; IL24; IL-24; CANDF6; IL-17F; ML1. Grade: ≥95%. Mole weight: 30-35 kDa. | |
| Indolicidin | Indolicidin is the smallest of the naturally known occurring linear antimicrobial peptides, containing the highest percentage of tryptophan of any known protein, and consists of only six different amino acids. Indolicidin has been shown to be a fairly potent antimicrobial peptide with activity against a variety of microorganisms, fungi, and protozoa. Uses: Anti-infective agents. Synonyms: cationic antimicrobial peptide; H-Ile-Leu-Pro-Trp-Lys-Trp-Pro-Trp-Trp-Pro-Trp-Arg-Arg-NH2; L-isoleucyl-L-leucyl-L-prolyl-L-tryptophyl-L-lysyl-L-tryptophyl-L-prolyl-L-tryptophyl-L-tryptophyl-L-prolyl-L-tryptophyl-L-arginyl-L-argininamide. Grade: >98%. CAS No. 140896-21-5. Molecular formula: C100H132N26O13. Mole weight: 1906.28. | |
| JB-95 | JB-95, a β-hairpin macrocyclic peptide, exhibits potent antimicrobial activity against Escherichia coli. JB-95 can selectively disrupt the outer membrane but not the inner membrane of E. coli [1]. Uses: Scientific research. Group: Peptides. CAS No. 1873323-60-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P5753. | |
| Kyotorphin | Kyotorphin is an endogenou neuroactive dipeptide with analgesic properties. Kyotorphin possesses anti-inflammatory and antimicrobial activity. Kyotorphin levels in cerebro-spinal fluid correlate negatively with the progression of neurodegeneration in Alzheimer's Disease patients [1]. Uses: Scientific research. Group: Peptides. CAS No. 70904-56-2. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-122381. | |
| LAH4 | LAH4, a-helix of the amphipathic peptide antibiotic, strongly interacts with phospholipid membranes, exhibiting in vitro transfection efficiency. The LAH4 family of histidine-rich peptides exhibits potent antimicrobial and DNA transfection activities, both of which require interactions with cellular membranes. Synonyms: LAH 4; LAH-4; Lys-Lys-Ala-Leu-Leu-Ala-Leu-Ala-Leu-His-His-Leu-Ala-His-Leu-Ala-Leu-His-Leu-Ala-Leu-Ala-Leu-Lys-Lys-Ala; L-lysyl-L-lysyl-L-alanyl-L-leucyl-L-leucyl-L-alanyl-L-leucyl-L-alanyl-L-leucyl-L-histidyl-L-histidyl-L-leucyl-L-alanyl-L-histidyl-L-leucyl-L-alanyl-L-leucyl-L-histidyl-L-leucyl-L-alanyl-L-leucyl-L-alanyl-L-leucyl-L-lysyl-L-lysyl-L-alanine. Grade: ≥95%. Molecular formula: C132H228N38O27. Mole weight: 2779.46. | |
| Lantibiotic Mersacidin | Lantibiotic Mersacidin is an antibacterial peptide isolated from Bacillus sp. It has activity against gram-positive bacteria. Uses: Lantibiotic mersacidin is a widely-regarded naturally occurring antimicrobial peptide that belongs to a class of antimicrobial peptides known as lantibiotics. it has a unique structure and antimicrobial mechanism, making it potentially valuable in the development of new antimicrobial drugs. like many other antimicrobial peptides, lantibiotic mersacidin has high biostability and antimicrobial activ. Synonyms: Mersacidin. Molecular formula: C80H120N20O21S4. Mole weight: 1826.2. | |
| LEAP-2 | LEAP-2 is an antimicrobial peptide derived from human blood [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Human liver expressed antimicrobial peptide-2. CAS No. 1683582-94-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P5645. | |
| Leukocyte Proteinase-3 (169-177) | Leukocyte Proteinase-3 (169-177) is amino acids 169 to 177 fragment of Leukocyte Proteinase-3. Proteinase-3 is a serine protease enzyme expressed mainly in neutrophil granulocytes. In human neutrophils, proteinase 3 contributes to the proteolytic generation of antimicrobial peptides. | |
| LL-37, human | LL-37, human is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity. LL-37, human could help protect the cornea from infection and modulates wound healing [1] [2] [3]. Uses: Scientific research. Group: Peptides. CAS No. 154947-66-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P1222. | |
| LL-37, human TFA | LL-37, human TFA is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity. LL-37, human TFA could help protect the cornea from infection and modulates wound healing[1][2][3]. Uses: Scientific research. Group: Peptides. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P1222A. | |
| Lycosin-I | Lycosin-I is a 24-residue cationic anticancer peptide derived from Lycosa singorensis with high structural similarity to several cationic and amphiphilic antimicrobial peptides. Lycosin-I showed rapid, selective and broad-spectrum bactericidal activity and a synergistic effect with traditional antibiotics. | |
| Microcin J25 | The bacteriocin microcin J25 (MccJ25) inhibits the growth of Gram-negative pathogens including Salmonella and Shigella species, and Escherichia coli. Uses: Microcin j25 is a small antimicrobial peptide produced by certain strains of escherichia coli, a common bacterium found in the human intestine. it belongs to a class of antimicrobial peptides called bacteriocins, which are natural compounds produced by bacteria that inhibit the growth of closely related species. what is particularly interesting about microcin j25 is its stability, potency, and spe. Synonyms: MccJ25. | |
| Murepavadin TFA | Murepavadin (POL7080) (TFA), a 14-amino-acid cyclic peptide, is a highly potent, specific antibiotic. Murepavadin exhibits a potent antimicrobial activity for P. aeruginosa with MIC50 and MIC90 values both of 0.12 mg/L. Murepavadin also can target the lipopolysaccharide transport portin D. Murepavadin can be used for the research of bacterial resistance[1][2]. Uses: Scientific research. Group: Peptides. Alternative Names: POL7080 TFA. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-P1674A. | |
| Myeloid antimicrobial peptide | BMAPs (bovine myeloid antimicrobial peptides) are bovine cathelicidins that share many structural and functional features with human cathelicidin. | |
| Myeloid cathelicidin 1 | Cathelicidin-derived antimicrobial peptides are a component of the peptide-based host defense of neutrophils and epithelia, with a widespread distribution in mammals. A broad spectrum of antimicrobial activity was demonstrated for eCATH-1 and eCATH-3, while the equine cathelicidin, eCATH-2 had antibacterial activity restricted to E. coli, S. aureus. Synonyms: CATH-1 protein; CAP18; eCATH-1. | |
| Myeloid cathelicidin 2 | Cathelicidin-derived antimicrobial peptides are a component of the peptide-based host defense of neutrophils and epithelia, with a widespread distribution in mammals. A broad spectrum of antimicrobial activity was demonstrated for eCATH-1 and eCATH-3, while the equine cathelicidin, eCATH-2 had antibacterial activity restricted to E. coli, S. aureus. Synonyms: eCATH-2. | |
| Myeloid cathelicidin 3 | Cathelicidin-derived antimicrobial peptides are a component of the peptide-based host defense of neutrophils and epithelia, with a widespread distribution in mammals. A broad spectrum of antimicrobial activity was demonstrated for eCATH-1 and eCATH-3, while the equine cathelicidin, eCATH-2 had antibacterial activity restricted to E. coli, S. aureus. Furthermore, eCATH-3 showed potent activity against some fungi like C. neoformans and Rhodotorula rubra, but its activity depends on the salt concentration being strongly inhibited at the physiological salt concentration. Synonyms: eCATH-3. | |
| Myticin C | Myticins, antimicrobial peptides that have been previously characterized, were constitutively expressed in a fraction of mussel hemocytes and showed antiviral activity against OsHV-1. Moreover, myticin C peptides showed antiviral activity against human herpes simplex viruses 1 (HSV-1) and 2 (HSV-2). Synonyms: Myt C. | |
| Native Human Proteinase 3 | Proteinase 3 also known as PRTN3 is an enzyme that in humans is encoded by the PRTN3 gene. PRTN3 is a serine protease enzyme expressed mainly in neutrophil granulocytes. Its exact role in the function of the neutrophil is unknown, but, in human neutrophils, proteinase 3 contributes to the proteolytic generation of antimicrobial peptides. It is also the epitope of anti-neutrophil cytoplasmic antibodies (ANCAs) of the c-ANCA (cytoplasmic subtype) class, a type of antibody frequently found in the disease granulomatosis with polyangiitis (formerly known as "Wegener's granulomatosis"). Group: Enzymes. Synonyms: PRTN3; proteinase 3; ACPA; AGP7; C-ANCA; CANCA; MBN; MBT; NP-4; NP4; P29; PR-3; PR3; EC 3.4.21.76. Enzyme Commission Number: EC 3.4.21.76. CAS No. 128028-50-2. Purity: > 96% (SDS-PAGE). PRTN3. Activity: Typically > 0.1 U/mg protein. Storage: -20°C. Form: Liquid. Source: Human Neutrophils. Species: Human. PRTN3; proteinase 3; ACPA; AGP7; C-ANCA; CANCA; MBN; MBT; NP-4; NP4; P29; PR-3; PR3; EC 3.4.21.76. Cat No: NATE-0620. |  |
| Omiganan | Omiganan is a cationic antimicrobial peptide. Omiganan as an analogue of indolicidin shows activity against gram-positive and gram-negative bacteria but also Candida spp. isolates. Omiganan can be used for the research of alcohol nose and acne [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 204248-78-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105048. | |
| Opistoporin-4 | Opistoporin-4 is an antimicrobial peptide found in Opistophthalmus carinatus (African yellow leg scorpion), and has antibacterial and antifungal activity. Synonyms: Opistoporin4; OP4; Non-disulfide-bridged peptides 3.7; NDBP-3.7. Grade: >85%. Molecular formula: C217H356N60O62. Mole weight: 4797.58. | |
| P-113 | P-113 is an antimicrobial peptide (AMP) derived from the human salivary protein histatin 5. P-113 is active against clinically important microorganisms such as Pseudomonas spp., Staphylococcus spp., and C. albicans [1]. Uses: Scientific research. Group: Peptides. CAS No. 190673-58-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P2148. | |
| Panusin | Panusin is an antimicrobial peptide found in Panulirus argus (Caribbean spiny lobster, Palinurus argus), and has antibacterial activity against gram-positive bacteria S.aureus and B.subtilis as well as against Gram-negative bacteria E.coli and K.pneumoniae. Panusin represents a new family of β-defensin-like peptides in invertebrates. Grade: >98%. | |
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