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100mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C38H52N6O7. CAS No. 198904-31-3. Prepack ID 89984074-100mg. Molecular Weight 704.86. See USA prepack pricing.
Atazanavir (BMS-232632) is a highly selective and orally active HIV-1 protease inhibitor. Atazanavir is a substrate and inhibitor of CYP3A4 , and an inhibitor of P-glycoprotein (P-gp). Atazanavir is also a SARS-CoV 3CL pro inhibitor with an IC 50 of 3.49 μM. Atazanavir inhibits cardiac fibrosis, hyperlipidemia and induces malignant glioma death [1] [2] [3] [4] [5] [6] [7] [8]. Uses: Scientific research. Group: Natural products. Alternative Names: BMS-232632. CAS No. 198904-31-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17367.
Atazanavir
Atazanavir is a HIV-1 protease inhibitor, used in the anti-retroviral therapy of adult and sometimes paediatric patients infected with HIV. In in vitro studies with human pulmonary epithelial cells, atazanavir has been studied as a potential inhibitor of SARS-CoV-2 Mpro protease, with the aim of halting viral replication. Group: Biochemicals. Alternative Names: 3, 12-Bis (1, 1-dimethylethyl) -8-hydroxy-4, 11-dioxo-9- (phenylmethyl) -6-[[4- (2-pyridinyl) phenyl]methyl]-dimethyl ester; (3S,8S, 9S, 12S) -2, 5, 6, 13-Pentaazatetradecane dioic acid; BMS-232632. Grades: Highly Purified. CAS No. 198904-31-3. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C??H??N?O?, Molecular Weight: 704.86. US Biological Life Sciences.
Worldwide
Atazanavir
Atazanavir is a novel and potent azapeptide protease inhibitor that specifically inhibits the human immunodeficiency virus type 1 (HIV-1) protease enzyme with inhibition constant Ki of 66 nmol/L and also inhibits the viral replication of HIV-1 with 50% effective concentration EC50 ranging from 2.6 to 5.3 nmol/L. Atazanavir binds to HIV-1 protease preventing the cleavage of gag and gag-pol polyproteins, which results in the formation of immature virions in HIV-1-infected cells. Atazanavir has a different C-2 symmetric chemical structure and a generally greater antiretroviral potency in various HIV strains compared to other protease inhibitors, including indinavir, nelfinavir, ritonavir, saquinavir and amprenavir. Synonyms: Atazanavir ; Reyataz ; Atazanavir sulfate ; CGP75136 ; CGP75176 ; CGP75355 ; BMS232632 ; CGP 73547 ; CGP 75136 ; CGP 75176 ; CGP 75355 ; CGP-73547 ; CGP-75136 ; CGP-75176 ; CGP-75355 ; BMS 232632 ; BMS-232632 ; BMS-232632-05 ; C413408. Grades: 0.98. CAS No. 198904-31-3. Molecular formula: C38H52N6O7. Mole weight: 704.869.
Atazanavir Bisulfate Salt
Atazanavir is a novel azapeptide HIV protease inhibitor (PI). Antiviral. Group: Biochemicals. Alternative Names: 3, 12-Bis (1, 1-dimethylethyl) -8-hydroxy-4, 11-dioxo-9- (phenylmethyl) -6-[[4- (2-pyridinyl) phenyl]methyl]-dimethyl Ester, (3S,8S, 9S, 12S) -2, 5, 6, 13-Pentaazatetradecane dioic Acid; BMS-232632; CGP-73547; Reyataz. Grades: Highly Purified. CAS No. 229975-97-7. Pack Sizes: 2.5mg. US Biological Life Sciences.
Atazanavir is a novel azapeptide protease inhibitor (PI). Group: Biochemicals. Alternative Names: 3, 12-Bis (1, 1-dimethylethyl) -8-hydroxy-4, 11-dioxo-9- (phenylmethyl) -6-[[4- (2-pyridinyl) phenyl]methyl]-dimethyl Ester, (3S,8S, 9S, 12S) -2, 5, 6, 13-Pentaazatetradecane dioic acid-d5; BMS 232632-d5; CGP 73547-d5; Reyataz-d5. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Atazanavir-d6
Atazanavir-d6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1092540-50-5. Molecular formula: C38H46D6N6O7. Mole weight: 710.91. Catalog: APB1092540505.
Atazanavir Di-tert-butyl Analog
An impurity of Atazanavir. Synonyms: Des-N-(methoxycarbonyl)-L-tert-leucine Bis-Boc Atazanavir. Grades: > 95%. CAS No. 198904-86-8. Molecular formula: C32H42N4O5. Mole weight: 562.72.
Atazanavir EP Impurity F (Atazanavir R,S,S,S-Diastereomer)
Atazanavir EP Impurity F (Atazanavir R,S,S,S-Diastereomer). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: methyl ((5S,8S,9S,14R)-8-benzyl-5-(tert-butyl)-9-hydroxy-15,15-dimethyl-3,6,13-trioxo-11-(4-(pyridin-2-yl)benzyl)-2-oxa-4,7,11,12-tetraazahexadecan-14-yl)carbamate. CAS No. 1332981-14-2. Molecular formula: C38H52N6O7. Mole weight: 704.86. Catalog: APB1332981142.
Atazanavir EP Impurity G (Atazanavir S,S,S,R-Diastereomer)
Atazanavir EP Impurity G (Atazanavir S,S,S,R-Diastereomer). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: methyl ((5R,8S,9S,14S)-8-benzyl-5-(tert-butyl)-9-hydroxy-15,15-dimethyl-3,6,13-trioxo-11-(4-(pyridin-2-yl)benzyl)-2-oxa-4,7,11,12-tetraazahexadecan-14-yl)carbamate. CAS No. 1332981-16-4. Molecular formula: C38H52N6O7. Mole weight: 704.86. Catalog: APB1332981164.
Atazanavir Hydrazine Analog Trihydrochloride
An intermediate for the synthesis of Atazanavir and the preparation of some peptide analogs. Synonyms: Des-N-(methoxycarbonyl)-L-tert-leucine Atazanavir Trihydrochloride. Grades: > 95%. CAS No. 198904-87-9. Molecular formula: C22H26N4O. 3 HCl. Mole weight: 362.48 3 36.46.
Atazanavir impurity
Cas No. 127406-56-8.
Atazanavir Impurity 1
An epimeric impurity of Atazanavir. Synonyms: (3S,8R,9S,12S)-3,12-Bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-6-[[4-(2-pyridinyl)phenyl]methyl]-,2,5,6,10,13-pentaazatetradecanedioic Acid 1,14-Dimethyl Ester. Grades: > 95%. CAS No. 1292296-09-3. Molecular formula: C38H52N6O7. Mole weight: 704.87.
Atazanavir Impurity 20
Atazanavir Impurity 20. Uses: For analytical and research use. Group: Impurity standards. CAS No. 102123-74-0. Molecular formula: C15H20ClNO3. Mole weight: 297.78. Catalog: APB102123740.
Atazanavir Impurity 6
Atazanavir Impurity 6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1006868-81-0. Molecular formula: C32H42N4O5. Mole weight: 562.71. Catalog: APB1006868810.
Atazanavir Impurity 8
Atazanavir Impurity 8. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1028634-76-5. Molecular formula: C36H50N6O5. Mole weight: 646.83. Catalog: APB1028634765.
Atazanavir Impurity B
An impurity of Atazanavir. Synonyms: 1-Boc-2-[4-(2-pyridinyl)benzylidene]hydrazine. Grades: > 95%. CAS No. 198904-85-7. Molecular formula: C17H21N3O2. Mole weight: 299.38.
Atazanavir Impurity C
An impurity of Atazanavir. Synonyms: (2R,3S)-3-(tert-Boc)amino-1,2-epoxy-4-phenylbutane; N-[(1S)-1-[(2R)-2-Oxiranyl]-2-phenylethyl]-carbamic Acid 1,1-Dimethylethyl Ester; (2R,3S)-(+)-3-tert-Butoxycarbonylamino-1,2-epoxy-4-phenylbutane; [(1S)-1-((2R)-Oxiranyl)-2-phenylethyl]carbamic Acid tert-Butyl Ester. Grades: > 95%. CAS No. 98760-08-8. Molecular formula: C15H21NO3. Mole weight: 263.34.
Atazanavir related compound A
An impurity of Atazanavir. Synonyms: N-(Methoxycarbonyl)-L-tert-leucine. Grades: > 95%. CAS No. 162537-11-3. Molecular formula: C8H15NO4. Mole weight: 189.21.
Atazanavir Related Compound A
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Atazanavir R,S,S,R-Diastereomer
An impurity of Atazanavir. Synonyms: (3R,8S,9S,12R)-Atazanavir. Grades: > 95%. CAS No. 1292296-11-7. Molecular formula: C38H52N6O7. Mole weight: 704.87.
Atazanavir R,S,S,S-diastereomer
An impurity of Atazanavir. Synonyms: (3R,8S,9S,12S)-Atazanavir. Grades: > 95%. CAS No. 1332981-14-2. Molecular formula: C38H52N6O7. Mole weight: 704.87.
Atazanavir S,S,R,S-Diastereomer
An impurity of Atazanavir. Synonyms: (3R,8R,9S,12R)-Atazanavir. Grades: > 95%. CAS No. 1292296-10-6. Molecular formula: C38H52N6O7. Mole weight: 704.87.
Atazanavir S,S,S,R-diastereomer
An impurity of Atazanavir. Synonyms: (3S,8S,9S,12R)-Atazanavir. Grades: > 95%. CAS No. 1332981-16-4. Molecular formula: C38H52N6O7. Mole weight: 704.87.
Atazanavir sulfate
100mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C38H52N6O7 · H2SO4. CAS No. 229975-97-7. Prepack ID 24906497-100mg. Molecular Weight 802.93. See USA prepack pricing.
Atazanavir sulfate
Atazanavir (BMS-232632) sulfate is a highly selective and orally active HIV-1 protease inhibitor. Atazanavir sulfate is a substrate and inhibitor of CYP3A4 , and an inhibitor of P-glycoprotein (P-gp). Atazanavir sulfate is also a SARS-CoV 3CL pro inhibitor with an IC 50 of 3.49 μM. Atazanavir sulfate inhibits cardiac fibrosis, hyperlipidemia and induces malignant glioma death [1] [2] [3] [4] [5] [6] [7] [8]. Uses: Scientific research. Group: Natural products. Alternative Names: BMS-232632 sulfate. CAS No. 229975-97-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17367A.
Atazanavir is a HIV protease inhibitor with Ki of 2.66 nM. It is an antiretroviral drug of the protease inhibitor (PI) class. Like other antiretrovirals, it is used to treat infection of human immunodeficiency virus. Uses: Hiv protease inhibitors. Synonyms: BMS-232632; BMS 232632; BMS232632; Reyataz. Grades: >98%. CAS No. 229975-97-7. Molecular formula: C38H52N6O7.H2SO4. Mole weight: 802.93.
(2S,3R)-Des-N-(methoxycarbonyl)-L-tert-leucine Bis-Boc Atazanavir is the isomer of Des-N-(methoxycarbonyl)-L-tert-leucine Bis-Boc Atazanavir (D290330), which is an intermediate for the synthesis of Atazanavir and the preparation of some peptide analogs. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C32H42N4O5, Molecular Weight: 562.7. US Biological Life Sciences.
Worldwide
Dealkyl Atazanavir
An impurity of Atazanavir. Synonyms: (3S,8S,9S,12S)-3,12-Bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-2,5,6,10,13-pentaazatetradecanedioic Acid 1,14-Dimethyl Ester. Grades: > 95%. CAS No. 1192224-24-0. Molecular formula: C26H43N5O7. Mole weight: 537.66.
(2S,3R)-3-(tert-Butoxycarbonylamino)-1,2-epoxy-4-phenylbutane is an intermediate in the synthesis of Atazanavir, a novel azapeptide HIV protease inhibitor used as an antiviral agent. Synonyms: threo-N-Boc-D-phenylalanine epoxide; 2-Methyl-2-propanyl {(1R)-1-[(2S)-2-oxiranyl]-2-phenylethyl}carba mate; (2S,3R)-3-phenylproline; trans-3-phenyl-l-proline; tert-butyl [(2R,3S)]-(-)-(1-oxiranyl-2-phenylethyl)carbamate; (2S)-[1'(R)-Boc-amino-2'-phenylethyl]oxirane; trans-3-phenyl-(S)-proline. Grades: ≥ 95%. CAS No. 156474-22-5. Molecular formula: C15H21NO3. Mole weight: 263.33.
(2S, 3S) -3-Amino-4-phenyl-1- ( (E) -1- (4- (pyridin-2-yl) benzyl) -2- (4- (pyridin-2-yl) benzylidene) hydrazinyl) butan-2-ol is an impurity of Atazanavir (A790051), a novel azapeptide HIV protease inhibitor (PI). Antiviral. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 25mg. Molecular Formula: C34H33N5O, Molecular Weight: 527.66. US Biological Life Sciences.
Worldwide
(2S,3S)-3-Boc-amino-1,2-epoxy-4-phenylbutane
Atazanavir intermediate. Enantiomer S. Group: Biochemicals. Grades: Highly Purified. CAS No. 98737-29-2. Pack Sizes: 10g, 25g, 50g, 100g. Molecular Formula: C??H??NO?, Identity (IR): Conforms to structure. US Biological Life Sciences.
Worldwide
3S-(t-Boc)amino-1,2-(s)-epoxy-4-phenylbutane
Atazanavir intermediate. Enantiomer S. Group: Biochemicals. Grades: Highly Purified. CAS No. 98737-29-2. Pack Sizes: 1g, 5g, 10g, 25g. Molecular Formula: C??H??NO?, Melting Point: 124-126°C. US Biological Life Sciences.
Worldwide
3-Tert-Butyldimethylsilyl-2-propyn-1-ol
3-Tert-Butyldimethylsilyl-2-propyn-1-ol, a widely used chemical compound in organic synthesis, serves as a safeguarding agent for alcohols, impeding undesired chemical reactions. It displays versatility in various applications ranging from stable protecting group synthesis to the development of potent drugs such as Atazanavir, a prominent HIV protease inhibitor. The compound's multifunctional competence and adaptability make it an indispensable component of organic synthesis. Synonyms: 3-(tert-butyldimethylsilyl)-2-propyn-1-ol. Grades: 95%. CAS No. 120789-51-7. Molecular formula: C9H18OSi. Mole weight: 170.32.
Brecanavir
Brecanavir is a tyrosyl-based arylsulfonamide, high-affinity, protease inhibitor (PI) for the treatment of human immunodeficiency virus type-1. This compound potently inhibited HIV-1 in cell culture assays with 50% effective concentrations (EC(50)s) of 0.2 to 0.53 nM and was equally active against HIV strains utilizing either the CXCR4 or CCR5 coreceptor, as was found with other PIs. Brecanavir had a <5-fold increase in EC(50)s against 80% of patient isolates tested and had a greater mean in vitro potency than amprenavir, indinavir, lopinavir, atazanavir, tipranavir, and darunavir. Brecanavir is by a substantial margin the most potent and broadly active antiviral agent among the PIs tested in vitro. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Brecanavir; GW-0385; GW-0385; GW0385; GW-640385; GW 640385; GW640385; GW-640385X; VX-385; VX 385; VX385. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 313682-08-5. Molecular formula: C33H41N3O10S2. Mole weight: 703.82. Purity:>98%. IUPACName: [(3aS,4R,6aR)-2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-yl] N-[(2S,3R)-4-[1,3-benzodioxol-5-ylsulfonyl(2-methylpropyl)amino]-3-hydroxy-1-[4-[(2-methyl-1,3-thiazol-4-yl)methoxy]phenyl]butan-2-yl]carbamate. Canonical SMILES: Cc1nc(cs1)COc2ccc(cc2)C[C@@H]([C@@H](CN(CC(C)C)S(=O)(=O)c3ccc4c(c3)OCO4)O)NC(=O)O[C@H]5CO[C@@H]6[C@H]5CCO6. Product ID: ACM313682085-1. Alfa Chemistry ISO 9001
Brecanavir
Brecanavir is a tyrosyl-based arylsulfonamide, high-affinity, protease inhibitor (PI) for the treatment of human immunodeficiency virus type-1. This compound potently inhibited HIV-1 in cell culture assays with 50% effective concentrations (EC(50)s) of 0.2 to 0.53 nM and was equally active against HIV strains utilizing either the CXCR4 or CCR5 coreceptor, as was found with other PIs. Brecanavir had a <5-fold increase in EC(50)s against 80% of patient isolates tested and had a greater mean in vitro potency than amprenavir, indinavir, lopinavir, atazanavir, tipranavir, and darunavir. Uses: Hiv-1 protease inhibitor. Synonyms: Brecanavir; UNII-E367I8C7FI; CHEMBL206031; GW-0385; GW-640385; GW-640385X; VX-385; GW0385; GW640385; GW640385X; VX385; GW 0385; GW 640385; GW 640385X; VX 385; [(3aS,4R,6aR)-2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-yl] N-[(2S,3R)-4-[1,3-benzodioxol-5-ylsulfonyl(2-methylpropyl)amino]-3-hydroxy-1-[4-[(2-methyl-1,3-thiazol-4-yl)methoxy]phenyl]butan-2-yl]carbamate. Grades: ≥98%. CAS No. 313682-08-5. Molecular formula: C33H41N3O10S2. Mole weight: 703.82.
CGP-75355
CGP-75355 is an HIV Protease inhibitor (EC50= 0.7 nM). Uses: Hiv protease inhibitors. Synonyms: CGP-75355; CGP 75355; CGP75355; UNII-4ZE7DBE752; methyl N-[(2S)-1-[2-[(2S,3S)-2-hydroxy-3-[[(2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoyl]amino]-4-phenylbutyl]-2-[(4-phenylphenyl)methyl]hydrazinyl]-3,3-dimethyl-1-oxobutan-2-yl]carbamate; 232632, BMS; 3,12-bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-6-((4-(2-pyridinyl)phenyl)methyl)-2,5,6,10,13-pentaazatetradecanedioic acid dimethyl ester; atazanavir; atazanavir sulfate; BMS 232632; BMS 232632 05; BMS-232632; BMS-232632-05; BMS232632; BMS23263205. Grades: >98%. CAS No. 191594-64-6. Molecular formula: C39H53N5O7. Mole weight: 703.87.
Cobicistat
Cobicistat is a potent inhibitor of cytochrome P450 3A enzymes, including the important CYP3A4 subtype. It also inhibits intestinal transport proteins, increasing the overall absorption of several HIV medications, including atazanavir, darunavir and tenofovir alafenamide fumarate. Uses: Anti-hiv agents. Synonyms: Cobicistat, GS-9350; GS 9350; GS9350. Grades: 0.99. CAS No. 1004316-88-4. Molecular formula: C40H53N7O5S2. Mole weight: 776.028.
MOC-L-Tert-Leucine
MOC-L-Tert-Leucine is used as a pharmaceutical intermediate for the synthesis of drugs such as Atazanavir. CAS No. 162537-11-3. Product ID: PAP-0021. Molecular formula: C8H15NO4. Category: Amino acid. Product Keywords: Amino Acid Series; MOC-L-Tert-Leucine; PAP-0021; Amino acid; C8H15NO4; 162537-11-3. EC Number: 431-620-3. Physical State: powder. Solubility: Soluble in ethyl acetate and methanol. Storage: 2-8°C. Boiling Point: 320.9±25.0 °C(Predicted). Melting Point: 109°C. Density: 1.126±0.06 g/cm3(Predicted).
N-Acetyl-S-[4-(2-pyridinyl)benzyl]-L-cysteine
N-Acetyl-S-[4-(2-pyridinyl)benzyl]-L-cysteine is a metabolite of Atazanavir, which is an antiretroviral medication used to treat HIV/AIDS. Synonyms: N-Acetyl-S-(4-(pyridin-2-yl)benzyl)-L-cysteine; L-Cysteine, N-acetyl-S-[[4-(2-pyridinyl)phenyl]methyl]-; (R)-2-acetamido-3-((4-(pyridin-2-yl)benzyl)thio)propanoic acid. Grades: ≥95%. CAS No. 1391068-09-9. Molecular formula: C17H18N2O3S. Mole weight: 330.40.
threo-N-Boc-L-phenylalanine epoxide
Atazanavir intermediate. Enantiomer S. Synonyms: (2S,3S)-3-(Boc-amino)-1,2-epoxy-4-phenylbutane; (2S,3S)-1,2-Epoxy-3-(tert-butoxycarbonylamino)-4-phenylbutane. Grades: ≥ 98 % by GC. CAS No. 98737-29-2. Molecular formula: C15H21NO3. Mole weight: 263.33.
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