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Avermectin. Uses: For analytical and research use. Group: Impurity standards. CAS No. 71751-41-2. Molecular Formula: C49H74O14. Mole Weight: 887.12. Catalog: APB71751412.
Avermectin A1a
Avermectin A1a is produced by the strain of Streptomyces avermitilis. It stimulates nerve cells to release Y-aminobutyric acid (GABA), which blocks the transmission of signals from the central nervous system to the motor nerve. It is not resistant to bacteria and fungi, but has strong activity to nematode parasites such as ancylostoma and Pteria, as well as insects such as flies. Abamectin B1a has the highest activity. Ivermectin obtained by catalytic hydrogenation contains 22 23- dihydroabamectin B1a (above 80%) and 22 23 dioxabamectin B1b (below 20%). Less active than B1a but less toxic. Used as repellent (subcutaneous or oral) for cattle, sheep and pigs, it is also effective against human filariasis. Synonyms: SCHEMBL1681257. CAS No. 65195-51-9. Molecular formula: C49H74O14. Mole weight: 887.10.
Avermectin A2a
Avermectin A2a is produced by the strain of Streptomyces avermitilis. It stimulates nerve cells to release Y-aminobutyric acid (GABA), which blocks the transmission of signals from the central nervous system to the motor nerve. It is not resistant to bacteria and fungi, but has strong activity to nematode parasites such as ancylostoma and Pteria, as well as insects such as flies. Abamectin B1a had the highest activity. Ivermectin obtained by catalytic hydrogenation contains 22,23-dihydroabamectin B1a (above 80%) and 22,23 dioxabamectin B1b(below 20%). Less active than B1a but less toxic. Used as repellent (subcutaneous or oral) for cattle, sheep and pigs, it is also effective against human filariasis. Synonyms: Avermectin A1a; SCHEMBL1681224. CAS No. 50914-15-3. Molecular formula: C49H76O15. Mole weight: 905.12.
Avermectin B1
Avermectin B1. Group: Biochemicals. Grades: Highly Purified. CAS No. 71751-41-2. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C49H74O14. US Biological Life Sciences.
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Avermectin B1a
Avermectin B1a. Group: Biochemicals. Grades: Highly Purified. CAS No. 65195-55-3. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C48H72O14. US Biological Life Sciences.
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Avermectin B1a
It is produced by the strain of Streptomyces avermitilis. Avermectin B1a is an antiparasitic agent that paralyzes nematodes without causing hypercontraction or flaccid paralysis. It is a macrocyclic lactone that makes up a large component of the anthelimintic Abamectin used to control parasitic nematodes in livestock. It also acts as an insecticide and acaricide. Uses: Active ingredient in some commercial ant bait traps. Synonyms: Abamectin B1a. Grades: >98%. CAS No. 65195-55-3. Molecular formula: C48H72O14. Mole weight: 873.08.
Avermectin B1a (5-O-Demethylavermectin A1a, Antibiotic C 076B1a)
Avermectin B1a is the major component (>80%) of the commerically available anthelmintic Abamectin (R) used to control parasitic nematodes in livestock. Avermectin B1a contains a secbutyl residue in the 24-position. In vitro and in vivo studies have shown this analogue is the more potent analogue in the commerical product. Group: Biochemicals. Alternative Names: 5-O-Demethylavermectin A1a, Antibiotic C 076B1a. Grades: Highly Purified. CAS No. 65195-55-3. Pack Sizes: 1mg. US Biological Life Sciences.
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Avermectin B1a aglycone
It is an acid degradation product produced by hydrolysis of the disaccharide unit of avermectin. It is an inhibitor of nematode larval development. It has no paralytic activity. It is an anthelmintic in animal health. Synonyms: (6R,13S,25R)-22,23-didehydro-5-O-demethyl-28-deoxy-6,28-epoxy-13-hydroxy-25-[(1S)-1-methylpropyl]-milbemycin B. Grades: >95% by HPLC. CAS No. 71828-14-3. Molecular formula: C34H48O8. Mole weight: 584.74.
Avermectin b1a ≥95% (HPLC)
Avermectin b1a ≥95% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g, 2.5g. US Biological Life Sciences.
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Avermectin B1a monosaccharide
It is an acid degradation product produced by selective hydrolysis of the terminal saccharide unit of avermectin. It is a potent inhibitor of nematode larval development. It has no paralytic activity. Synonyms: 4'-O-de(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-5-O-demethyl-avermectin A1a; 5-O-Demethyl-4'-O-de(2,6-dideoxy-3-O-methyl-α-L-glucopyranosyl)avermectin A1a; MSB 1a. Grades: >95% by HPLC. CAS No. 71831-09-9. Molecular formula: C41H60O11. Mole weight: 728.91.
Avermectin B1b (Antibiotic C 076B1b)
Avermectin B1b is the minor component (<20%) of the commerically available anthelmintic marketed as Abamectin(R) used to control parasitic nematodes in livestock. Avermectin B1b contains a isopropyl residue in the 24-position. In vitro and in vivo studies have shown this analogue to be active but less potent than the B1a analogue. Group: Biochemicals. Alternative Names: Antibiotic C 076B1b. Grades: Highly Purified. CAS No. 65195-56-4. Pack Sizes: 500ug. US Biological Life Sciences.
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Avermectin B2a
Avermectin B2a is produced by the strain of Streptomyces avermitilis. It stimulates nerve cells to release Y-aminobutyric acid (GABA), which blocks the transmission of signals from the central nervous system to the motor nerve. It is not resistant to bacteria and fungi, but has strong activity to nematode parasites such as ancylostoma and Pteria, as well as insects such as flies. Abamectin B1a has the highest activity. Ivermectin obtained by catalytic hydrogenation contains 22 23- dihydroabamectin B1a (above 80%) and 22 23 dioxabamectin B1b (below 20%). Less active than B1a but less toxic. Used as repellent (subcutaneous or oral) for cattle, sheep and pigs, it is also effective against human filariasis. Synonyms: SCHEMBL1681286. CAS No. 65195-57-5. Molecular formula: C48H74O15. Mole weight: 891.09.
25-?Cyclohexyl-?4'-?O-?de (2, ?6-?dideoxy-?3-?O-?methyl-?α -?L-?arabino-?hexopyranosyl) ?-?5-?demethoxy-?25-?de (1-?methylpropyl) ?-?5-?oxo-avermectin A1a is an intermediate in synthesizing 22,23-Didehydro Selamectin (D439445), an impurity of Selamectin (S247990) which is a topical parasiticide. Selamectin (S247990) is also used as a veterinary antihelminithic agent on animals. Group: Biochemicals. Grades: Highly Purified. CAS No. 404578-37-6. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C43H60O11, Molecular Weight: 752.93. US Biological Life Sciences.
25-?Cyclohexyl-?4'-?O-?de (2, ?6-?dideoxy-?3-?O-?methyl-?α -?L-?arabino-?hexopyranosyl) ?-?5-?O-?demethyl-?25-?de (1-?methylpropyl) ?-Avermectin A1a is an intermediate in synthesizing 22,23-Didehydro Selamectin (D439445), an impurity of Selamectin (S247990) which is a topical parasiticide. Selamectin (S247990) is also used as a veterinary antihelminithic agent on animals. Group: Biochemicals. Grades: Highly Purified. CAS No. 165108-44-1. Pack Sizes: 5mg, 10mg. Molecular Formula: C43H62O11, Molecular Weight: 754.95. US Biological Life Sciences.
25-Cyclohexyl-5-demethoxy-25-de(1-methylpropyl)-22,23-dihydro-5-oxo-avermectin A1a is an intermediate in synthesizing 4'-O-2,6-Dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl Selamectin (D440100), which s an impurity of Selamectin (S247990), a topical parasiticide. Selamectin (S247990) is also used as a veterinary antihelminithic agent on animals. Group: Biochemicals. Grades: Highly Purified. CAS No. 220119-16-4. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C50H74O14. US Biological Life Sciences.
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5-O-demethyl-28-hydroxy-Avermectin A1a
5-O-demethyl-28-hydroxy-Avermectin A1a. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-. Appearance: White to off-white solid. CAS No. 96722-46-2. Molecular formula: C48H72O15. Mole weight: 889.09. Purity: 0.95. Product ID: ACM96722462. Alfa Chemistry ISO 9001:2015 Certified.
5-O-Demethyl-28-oxo-Avermectin A1a
5-O-Demethyl-28-oxo-Avermectin A1a. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq]. Appearance: Pale yellow to light yellow solid. CAS No. 102190-68-1. Molecular formula: C48H70O15. Mole weight: 887.07. Purity: 0.98. IUPACName: (1'R,2R,3S,4'S,6S,8'R,10'E,12'S,13'S,14'E,16'Z,20'R,21'R,24'S)-2-[(2S)-butan-2-yl]-21',24'-dihydroxy-12'-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-3,11',13',22'-tetramethylspiro[2,3-dihydropyran-6,6'-3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene]-2',18'-dione. Canonical SMILES: CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\C(=O)O[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C. Product ID: ACM102190681. Alfa Chemistry ISO 9001:2015 Certified.
5-O-Demethyl-3,4,22,23-tetrahydro-avermectin A1a
5-O-Demethyl-3,4,22,23-tetrahydro-avermectin A1a. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3,4-Dihydro Ivermectin (Mixture of Diastereomers). Appearance: White to off-white solid. CAS No. 74567-01-4. Molecular formula: C48H76O14. Mole weight: 877.11. Purity: 0.95. IUPACName: (1R,4S,5'S,6R,6'R,8R,10E,12S,13S,14E,16E,20R,21R,24S)-6'-[(2S)-butan-2-yl]-21,24-dihydroxy-12-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16-triene-6,2'-oxane]-2-one. Canonical SMILES: CC[C@H](C)[C@@H]1[C@H](CC[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](CC([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C. Product ID: ACM74567014. Alfa Chemistry ISO 9001:2015 Certified.
5-O-Demethyl-4'', 5-bis-O-[ (1, 1-dimethylethyl) dimethylsilyl]-22, 23-dihydro-28-oxo-Avermectin A1a is an impurity of Ivermectin (I940800), an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Group: Biochemicals. Grades: Highly Purified. CAS No. 102190-51-2. Pack Sizes: 5mg, 25mg. Molecular Formula: C60H100O15Si2. US Biological Life Sciences.
5-O-Demethyl-4'',5-bis-O-[(1,1-dimethylethyl)dimethylsilyl]-22,23-dihydro-28-oxo-Avermectin A1a. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran], Avermectin A1a Deriv. Appearance: White solid. CAS No. 102190-51-2. Molecular formula: C60H100O15Si2. Mole weight: 1117.6. IUPACName: (1R,4S,5'S,6R,6'R,8R,12S,13S,20R,21R,24S)-6'-[(2S)-butan-2-yl]-21-[tert-butyl(dimethyl)silyl]oxy-12-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-[tert-butyl(dimethyl)silyl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-24-hydroxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2,18-dione. Canonical SMILES: CC[C@H](C)[C@@H]1[C@H](CC[C@@]2(O1)C[C@@H]3C[C@H](O2)CC=C([C@H]([C@H](C=CC=C4C(=O)O[C@H]5[C@@]4([C@@H](C=C([C@H]5O[Si](C)(C)C(C)(C)C)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O[Si](C)(C)C(C)(C)C)OC)OC)C)C. Product ID: ACM102190512. Alfa Chemistry ISO 9001:2015 Certified.
5-O-Demethyl-4'', 5-bis-O-[ (1, 1-dimethylethyl) dimethylsilyl]-22, 23-dihydro-Avermectin A1a is an impurity of Ivermectin (I940800), an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Group: Biochemicals. Grades: Highly Purified. CAS No. 82590-57-6. Pack Sizes: 5mg, 25mg. Molecular Formula: C60H102O14Si2. US Biological Life Sciences.
5-O-Demethyl-4'',5-bis-O-[(1,1-dimethylethyl)dimethylsilyl]-22,23-dihydro-Avermectin A1a. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran], Avermectin A1a deriv. Appearance: White to pale yellow solid. CAS No. 82590-57-6. Molecular formula: C60H102O14Si2. Mole weight: 1103.61. IUPACName: (1R,4S,5'S,6R,6'R,8R,12S,13S,20R,21R,24S)-6'-[(2S)-butan-2-yl]-21-[tert-butyl(dimethyl)silyl]oxy-12-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-[tert-butyl(dimethyl)silyl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-24-hydroxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one. Canonical SMILES: CC[C@H](C)[C@@H]1[C@H](CC[C@@]2(O1)C[C@@H]3C[C@H](O2)CC=C([C@H]([C@H](C=CC=C4CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O[Si](C)(C)C(C)(C)C)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O[Si](C)(C)C(C)(C)C)OC)OC)C)C. Product ID: ACM82590576. Alfa Chemistry ISO 9001:2015 Certified.
Mixture of avermectins, containing at least 80% of avermectin B1a (C48H72O14) and not more than 20% of avermectin B1b (C47H70O14). Used as acaricide, insecticide. Group: Biochemicals. Alternative Names: Avermectin B1; MK-936; Agri-Mek; Avid; Zephyr. Grades: Highly Purified. CAS No. 71751-41-2. Pack Sizes: 250mg. US Biological Life Sciences.
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delta2-Avermectin B1a
Δ2-Avermectin B1a is a degradation product produced by the reversible base-catalyzed isomerization of ivermectin B1a. It is less active than ivermectin against T. urticae (LC90s = 0.23 and 0.038 ppm, respectively). Synonyms: Avermectin A1a, 2,3-didehydro-5-O-demethyl-3,4-dihydro-, (4S)-; Δ2-4(R)-avermectin B1a; Δ2-Avermectin B1a. Grades: >95% by HPLC. CAS No. 110415-68-4. Molecular formula: C48H72O14. Mole weight: 873.07.
Doramectin is a biosynthetic avermectin derived from a mutant of the original Streptomyces avermitilis strain supplemented with a cyclohexylcaboxylic acid starting unit. Doramectin was developed as an anthelmintic for internal parasite control. The presence of the cyclohexyl group replacing the sec-butyl moiety affords greater hydrophobicity and longer biological half-life compared to avermectin. Like the other milbemycin / avermectins, it selectively binds to parasite glutamate-gated chloride ion channels and disrupts neurotransmission leading to paralysis and death of the parasite. Group: Biochemicals. Alternative Names: 25-Cyclohexyl-5-O-demethyl-25-de (1-methylpropyl) avermectin A1A; 25-Cylohexyl-avermectin B1; UK-67994; Dectomax. Grades: Highly Purified. CAS No. 117704-25-3. Pack Sizes: 10mg. US Biological Life Sciences.
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epi-Avermectin B1a
It is a base-catalysed intermediate in the decomposition of avermectin B1a. It has only very weak activity as a nematocide showing 100-fold less of biological activity compared with the parent avermectin. It is an environmental degradation product. Synonyms: Avermectin B1a, epi-; 2-epi-Abamectin; (2S)-5-O-demethyl-avermectin A1a. Grades: >95% by HPLC. CAS No. 106434-14-4. Molecular formula: C48H72O14. Mole weight: 873.08.
Ivermectin B1a is the major component (>80%) of the commercial anthelmintic, ivermectin. Members of the avermectin/milbemycin anthelmintic class exert their anthelmintic effects by binding to glutamate-gated chloride channels expressed on nematode neurones and pharyngeal muscle cells. The avermectins and milbemycins are also potent insecticides. The individual 25-sec-butyl (B1a) and 25-iso-propyl (B1b) components of ivermectin have received little separate study. Group: Biochemicals. Alternative Names: Ivermectin, Ivermectin B1a, 22, 23-Dihydro-avermectin B1a. Grades: Highly Purified. CAS No. 70161-11-4. Pack Sizes: 1mg. US Biological Life Sciences.
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28-Oxo Ivermectin B1a (Impurity)
28-Oxo Ivermectin B1a (Impurity). Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-O-Demethyl-22,23-dihydro-28-oxo-avermectin A1a. Appearance: White to off-white solid. CAS No. 102190-55-6. Molecular formula: C48H72O15. Mole weight: 889.08. Purity: 0.95. IUPACName: (1R,4S,5'S,6R,6'R,8R,10E,12S,13S,14E,16Z,20R,21R,24S)-6'-[(2S)-butan-2-yl]-21,24-dihydroxy-12-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2,18-dione. Canonical SMILES: CC[C@H](C)[C@@H]1[C@H](CC[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\C(=O)O[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C. Product ID: ACM102190556. Alfa Chemistry ISO 9001:2015 Certified.
3"-O-Demethyl ivermectin
3"-O-Demethyl ivermectin. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran], avermectin A1a deriv.3''-O-Desmethyldihydroavermectin B1a. Appearance: White solid. CAS No. 92137-95-6. Molecular formula: C47H72O14. Mole weight: 861.08. Purity: 0.95. IUPACName: (1R,4S,5'S,6R,6'R,8R,10Z,12S,13S,14Z,20R,21R,24S)-6'-[(2S)-butan-2-yl]-12-[(2R,4S,5S,6S)-5-[(2S,4S,5R,6S)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-21,24-dihydroxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one. Canonical SMILES: CC[C@H](C)[C@@H]1[C@H](CC[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(\[C@H]([C@H](/C=C\C=C4CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)O)OC)/C)C. Product ID: ACM92137956. Alfa Chemistry ISO 9001:2015 Certified.
5-Dehydroxyl-5-oxodoramectin. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran], avermectin A1a deriv.,25-Cyclohexyl-5-demethoxy-25-de(1-methylpropyl)-5-oxo-avermectin A1a (9CI). CAS No. 157483-78-8. Molecular Formula: C50H72O14. Mole Weight: 897.10. Catalog: APS157483788. SMILES: CO[C@H]1C[C@H] (O[C@H]2[C@H] (C)O[C@H] (C[C@@H]2OC)O[C@H]3[C@@H] (C)\C=C\C=C\4/CO[C@@H]5C (=O)C (=C[C@@H] (C (=O)O[C@H]6C[C@@H] (C\C=C\3/C)O[C@@]7 (C6)O[C@H] (C8CCCCC8)[C@@H] (C)C=C7)[C@]45O)C)O[C@@H] (C)[C@@H]1O. Format: Neat. Shipping: Room Temperature.
8,9-Z-Abamectin B1a
8,9-Z-Abamectin B1a is a photodegradation product of Avermectin B1a (A794665); a natural product derived from the soil actinomycete Streptomyces avermitilis. It is an antiparasitic agent that paralyzes nematodes without causing hypercontraction or flaccid paralysis. Group: Biochemicals. Grades: Highly Purified. CAS No. 113665-89-7. Pack Sizes: 1mg, 5mg. Molecular Formula: C48H72O14. US Biological Life Sciences.
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Abamectin
Avermectin B1 (Abamectin) is a widely used insecticide and anthelmintic. It is a mixture of avermectins containing more than 80% avermectin B1a and less than 20% avermectin B1b, which have very similar biological and toxicological properties. Avermectin B1 is a natural fermentation product of this bacterium. Synonyms: Avomec; Agri-Mek; Avid; Agrimek; Vertimec; Affirm; Zephyr; MK 936; MK 0936; NSC 758202; Avermectin B1; MK-936; Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran], avermectin B1 deriv.; A 14906; A 8612; Abamektin; Abamitel; Abarex; Abastate; Abastate EW; Abathor; Abba; Agador; AgMectin; Agri-Mek; Agri-Mek SC; Agrimec; Avermectin B1a-Avermectin B1b mixt.; Aversectin S; Avert; Avicta; Avicta 400FS; Avid 0.15EC; CHA 2061; CHA 2062; Dalamectin; Dalamektin; Epi-Mek; Fitoverm; Fitoverm M; Genesis Oral Drench; Genesis Pour-on for Cattle and Deer; Kraft; KRAFT 36 EC; L 676; Lirosect; Lyrosekt; Mectin; Phytoverm; PT 310; Rustomectin; STAN; Temprano; Vermitec; Vertigo (pesticide); Vertigo 018EC; Vertimec 018SC; Zoro. Grades: >95% a mixture of B1a and B1b. CAS No. 71751-41-2. Molecular formula: C48H72O14.C47H70O14. Mole weight: 1732.14.
delta2-Doramectin
An irreversible base degradation product of doramectin found in animals treated with doramectin and in the environment. It is formed by rearrangement of the naturally occurring 3-group in doramectin to the 2-position. It is an anthelmintic in animal health. Synonyms: (4S)-25-cyclohexyl-2,3-didehydro-5-O-demethyl-25-de(1-methylpropyl)-3,4-dihydro-avermectin A1a; Doramectin, delta2-; Δ2-Doramectin. Grades: >95% by HPLC. CAS No. 1987882-63-2. Molecular formula: C50H74O14. Mole weight: 899.11.
Doramectin
25-Cyclohexyl-5-O-demethyl-25-de(1-methylpropyl)avermectin. CAS No. 117704-25-3. Product ID: 2-08527. Molecular formula: C50H74O14. Mole weight: 899.11. Purity: 0.95. Source : veterinary use anti-parasitic.
Doramectin
Doramectin is a biosynthetic avermectin derived from a mutant of the original Streptomyces avermitilis strain supplemented with a cyclohexylcaboxylic acid starting unit. Doramectin was developed as an anthelmintic for internal parasite control. The presence of the cyclohexyl group replacing the sec-butyl moiety affords greater hydrophobicity and longer biological half-life compared to avermectin. Like the other milbemycin / avermectins, it selectively binds to parasite glutamate-gated chloride ion channels and disrupts neurotransmission leading to paralysis and death of the parasite. Group: Biochemicals. Grades: Highly Purified. CAS No. 117704-25-3. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Doramectin
Doramectin is a derivative of Ivermectin (HY-15310). Doramectin is a potent antiparasitic antibiotic. Doramectin is an active compound against S.mansoni in an NMRI mouse infection model. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 25-CYCLOHEXYL-5-O-DEMETHYL-25-DE(1-METHYLPROPYL)AVERMECTIN;DORAMECTIN;Doramectin VETRANAL;Doromectin;_x00B_25-Cclohexyl-avermectin B1;25-Cyclohexyl-5-O-demethyl-25-de(1-methylpropyl)avermectin A1A;Dectoma;UK-67994. Product Category: Inhibitors. Appearance: Solid. CAS No. 117704-25-3. Molecular formula: C50H74O14. Mole weight: 899.11. Purity: 0.9896. Canonical SMILES: CO[C@@H]1[C@@H](O[C@]2([H])O[C@@H](C)[C@H](O)[C@@H](OC)C2)[C@H](C)O[C@@]([H])(O[C@H](/C(C)=C/C[C@]3([H])C[C@]([H])(OC4=O)C[C@]5(C=C[C@H](C)[C@@H](C6CCCCC6)O5)O3)[C@@H](C)/C=C/C=C7CO[C@@]8([H])[C@]\7(O)[C@@]4([H])C=C(C)[C@H]8O)C1. Product ID: ACM117704253. Alfa Chemistry ISO 9001:2015 Certified.
Doramectin monosaccharide
It is an acid degradation product produced by selective hydrolysis of the terminal saccharide unit of doramectin. It is a potent inhibitor of nematode larval development and an anthelmintic in animal health. Synonyms: 25-cyclohexyl-4'-O-de(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-O-demethyl-25-de(1-methylpropyl)-avermectin A1a. Grades: >95% by HPLC. CAS No. 165108-44-1. Molecular formula: C43H62O11. Mole weight: 754.95.
Emamectin
Emamectin, also called as Proclaim, is widely used as an insecticide because of its chloride channel activation property. Synonyms: (4''R)-4''-Deoxy-4''-(methylamino)avermectin B1; emamectin B1a. CAS No. 119791-41-2. Molecular formula: C49H75NO13. Mole weight: 886.133.
Emamectin B1a
It is a semi-synthetic 4''-epimethylamino analogue of avermectin B1a prepared by oxidation of the 4''-hydroxy moiety and reductive amination. It has strong insecticidal efficacy. Synonyms: L 656748; (4''R)-5-O-Demethyl-4''-deoxy-4''-(methylamino)avermectin A1a; 4''-Deoxy-4''-epi-(methylamino)avermectin B1a. Grades: >99% by HPLC. CAS No. 121124-29-6. Molecular formula: C49H75NO13. Mole weight: 886.12.
Emamectin B1b
It is a semi-synthetic 4-epimethylamino analogue of avermectin B1b. It is prepared by oxidation of the 4-hydroxy moiety and reductive amination. It has strong insecticidal efficacy. Synonyms: Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-4''-deoxy-4''-(methylamino)-25-(1-methylethyl)-, (4''R)-. Grades: >99% by HPLC. CAS No. 121424-52-0. Molecular formula: C48H73NO13. Mole weight: 872.09.
Emamectin Benzoate
A mixture of semi-synthetic Avermectins. Exists as the anhydrous and various hydrated forms having different crystal morphologies. Insecticide. Group: Biochemicals. Alternative Names: 4''-Deoxy-4''-epi-N- (methylamino) avermectin B1 Benzoate; MK 244; Methylamino abamectin benzoate; Proclaim; Proclaim 5SG; Sch 58854; Shot-Wan; Slice. Grades: Highly Purified. CAS No. 155569-91-8. Pack Sizes: 10mg. US Biological Life Sciences.
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Emamectin Benzoate
Emamectin Benzoate (MK-244) is an orally active nervoussystem toxicant by binding g-aminobutyric ( GABA ) receptor in insects. Emamectin Benzoate is one of semi-synthetic derivative of Avermectin (HY-15311) with a broadspectrum of insecticidal and acaricidal activity. Emamectin Benzoate induces ROS-mediated DNA damage and cell apoptosis. Emamectin Benzoate, a mixture of the natural Emamectin B1a benzoate and Emamectin B1b benzoate, has the main component of Emamectin B1a benzoate [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-244. CAS No. 155569-91-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0837.
Emamectin Benzoate
Emamectin Benzoate (MK-244) is an orally active nervoussystem toxicant by binding g-aminobutyric (GABA) receptor in insects. Emamectin Benzoate is one of semi-synthetic derivative of Avermectin (HY-15311) with a broadspectrum of insecticidal and acaricidal activity. Emamectin Benzoate induces ROS-mediated DNA damage and cell apoptosis. Emamectin Benzoate, a mixture of the natural Emamectin B1a benzoate and Emamectin B1b benzoate, has the main component of Emamectin B1a benzoate. Uses: Emamectin benzoate is usually found as a mixture of two forms, which is a cream coloured powder. it is non corrosive and stable, except that it is flammable and may explode in the presence of strong oxidising agents. emamectin benzoate is a pesticide which works by interfering with nerve impulses in the body. it is used in agricultural settings to control insects amongst vegetable crops such as ca. Product Category: Inhibitors. Appearance: white to off-white yellowish powder. CAS No. 155569-91-8. Molecular formula: C56H81NO15 (emamectin B1a benzoate) + C55H79NO15 (emamectin B1b benzoate). Mole weight: 1008.24. Purity: 0.95. Canonical SMILES: C[C@H]1O[C@@H](O[C@@]2([H])[C@H](C)O[C@@H](O[C@]([C@@H](C)/C=C/C=C3CO[C@@]4([H])[C@]\3(O)[C@H]5C=C(C)[C@H]4O)([H])/C(C)=C/C[C@@H]6C[C@H](OC5=O)C[C@]7(C=C[C@H](C)[C@@H](C(C)C)O7)O6)C[C@@H]2OC)C[C@@H](OC)[C@@H]1NC.C[C@H]8O[C@@H](O[C@@]9([H])[C@H](C)O[C@@H](O[C@]([C@@H](C)/C=C/C=C%10CO[C@@]%11([H])[C@]\%
Epi-doramectin
It is a base-catalysed intermediate in the decomposition of doramectin. It is formed by epimerisation at the 2-position which ultimately rearranges irreversibly to the isomeric alkene analogue. Synonyms: (2S)-25-cyclohexyl-5-O-demethyl-25-de(1-methylpropyl)-avermectin A1a; Doramectin, epi-. Grades: >95% by HPLC. CAS No. 1987882-62-1. Molecular formula: C50H74O14. Mole weight: 899.11.
epi-Ivermectin B1a
Epi-Ivermectin B1a is a degradation product produced by the reversible base-catalyzed isomerization of ivermectin B1a. It is less active than ivermectin against T. urticae (LC90s = 4.0 and 0.038 ppm, respectively). Synonyms: 5-O-demethyl-22,23-dihydro-avermectin A1a; 2-dehydro-4-dihydro Avermectin B1a; epi-dihydro Avermectin B1a; 22,23-dihydro Avermectin B1a; 2-epi-Ivermectin B1a. Grades: >95% by HPLC. Molecular formula: C48H74O14. Mole weight: 875.09.
Eprinomectin
A mixture of semi-synthetic Avermectins; containing 90% or more of component B1a and 10% or less of component B1b. Antiparasitic. Group: Biochemicals. Alternative Names: (4''R)-4''-(Acetylamino)-4''-deoxyavermectin B1; Eprinex; MK 397. Grades: Highly Purified. CAS No. 123997-26-2. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Eprinomectin
Eprinomectin is a semi-synthetic GABA signaling potentiator used to inhibit bacterial infections. It causes neuromuscular paralysis in microbes and parasites. Eprinomectin is an avermectin selected for development as a topical endectocide. Synonyms: Eprinex; Ivomec Eprinex; MK 397; MK-397; MK397. Grades: >98%. CAS No. 123997-26-2. Molecular formula: C50H75NO14. Mole weight: 914.13.
Eprinomectin
Eprinomectin (MK-397) is a type of avermectin. Eprinomectin, as a broad-spectrum fungicide, has insecticidal, insecticidal and acaricidal activities. Eprinomectin induces apoptosis and autophagy in prostate cancer cells and has antitumor activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-397. CAS No. 123997-26-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 250 mg. Product ID: HY-12643.
Eprinomectin B1a
It is a semi-synthetic 4''-epimethylamino analogue of avermectin B1b prepared by oxidation of the 4''-hydroxy moiety and reductive amination. Members of the Avermectin/Milbemycin class exert their insecticidal/anthelmintic effects by binding to glutamate-gated chloride channels expressed on nematode neurones and pharyngeal muscle cells. Synonyms: (4''R)-4''-(Acetylamino)-5-O-demethyl-4''-deoxyavermectin A1a; Avermectin A1a, 4'-(acetylamino)-5-O-demethyl-4'-deoxy-, (4'R)-; Eprinomectin component B1a. Grades: >99% by HPLC. CAS No. 133305-88-1. Molecular formula: C50H75NO14. Mole weight: 914.13.
Eprinomectin B1b
It is a semi-synthetic analogue of avermectin B1b prepared by oxidation of the 4''-hydroxy moiety and reductive amination followed by acetylation. It is the minor component (<10%) of the commercial product for endo- and exo-parasite control, eprinomectin. It is a potent insecticide and acaricide. Synonyms: (4''R)-4''-(Acetylamino)-5-O-demethyl-25-de(1-methylpropyl)-4''-deoxy-25-(1-methylethyl)avermectin A1a; Eprinomectin component B1b. Grades:>99% by HPLC. CAS No. 133305-89-2. Molecular formula: C49H73NO14. Mole weight: 900.10.
Ivermectin
Ivermectin is a glutamate-gated chloride channel (GluCls) activator, which is used as an antiparasitic drug for the treatment of certain parasitic roundworm infections. Ivermectin inhibits the chloride channels of helminthic parasites and has been shown to have clinical efficacy for the treatment of onchocerciasis, strongyloidiasis, and ectoparasitic infection. Ivermectin is a mixture of mostly Ivermectin B1a (>80%) with some Ivermectin B1b (<20%), which are macrolides from Streptomyces avermitilis. Uses: Antiparasitic agents. Synonyms: Ivermectin B1a and Ivermectin B1b (Mixture); Avermectin H2B1a and Avermectin H2B1b (Mixture); Dihydroavermectin B1a and Dihydroavermectin B1b (Mixture); 22,23-Dihydroavermectin B1a and 22,23-Dihydroavermectin B1b (Mixture). Grades: ≥95%. CAS No. 70288-86-7. Molecular formula: C48H74O14.C47H72O14. Mole weight: 1736.16.
Ivermectin B1a
It is the major component (>80%) of the commercial anthelmintic, ivermectin. It exerts its anthelmintic effects by binding to glutamate-gated chloride channels expressed on nematode neurones and pharyngeal muscle cells. It is also a potent insecticide. Synonyms: Dihydroavermectin B1a; Ivermectin; 22,23-Dihydroavermectin B1a; 5-O-Demethyl-22,23-dihydro-avermectin A1a; Ivermectin Impurity I. Grades: >95% by HPLC. CAS No. 70161-11-4. Molecular formula: C48H74O14. Mole weight: 875.12.
Ivermectin B1a
Ivermectin B1a, a derivative of Avermectin B1a (HY-15308), is a main component of Ivermectin (HY-15310) [1]. Ivermectin (MK-933) is a broad-spectrum anti-parasite agent. Ivermectin is a candidate therapeutic against SARS-CoV-2/COVID-19 [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 71827-03-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg. Product ID: HY-126937.
Ivermectin B1a
Ivermectin B1a, a derivative of Avermectin B1a (HY-15308), is a main component of Ivermectin (HY-15310). Ivermectin (MK-933) is a broad-spectrum anti-parasite agent. Ivermectin is a candidate therapeutic against SARS-CoV-2/COVID-19. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-O-Demethyl-22,23-dihydro-avermectin A1a. Product Category: Inhibitors. Appearance: White to off-white solid. CAS No. 71827-03-7. Molecular formula: C48H74O14. Mole weight: 875.09. Purity: 0.85. IUPACName: (1R,4S,5'S,6R,6'R,8R,10E,12S,13S,14E,16E,20R,21R,24S)-6'-[(2S)-butan-2-yl]-21,24-dihydroxy-12-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one. Canonical SMILES: CC[C@H](C)[C@@H]1[C@H](CC[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C. Product ID: ACM71827037-1. Alfa Chemistry ISO 9001:2015 Certified.
Ivermectin B1a
Ivermectin B1a is a major component of Ivermectin, a semi-synthetic derivative of Abamectin; consists of a mixture of not less than 80% component B1a and not more than 20% component B1b. Antihelmintic (Onchocerca). An invitro inhibitor of SARS-CoV-2/ Covid-19. Group: Biochemicals. Alternative Names: 5-O-Demethyl-22,23-dihydro-avermectin A1a; 2,23-Dihydroavermectin B1a; Dihydroavermectin B1a. Grades: Highly Purified. CAS No. 71827-03-7. Pack Sizes: 5mg, 10mg. Molecular Formula: C??H??O??, Molecular Weight: 875.09. US Biological Life Sciences.
Worldwide
Ivermectin B1a-D2
Ivermectin B1a-D2. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-O-Demethyl-22,23-dihydro-avermectin A1a-D2. Appearance: Pale Beige to Brown Solid. CAS No. 71827-03-7 (Unlabelled). Molecular formula: C48H72D2O14. Mole weight: 877.11. Purity: 0.94. IUPACName: (1R,4S,5'S,6R,6'R,8R,10E,12S,13S,14E,16E,20R,21R,24S)-6'-[(2S)-butan-2-yl]-21,24-dihydroxy-12-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one. Canonical SMILES: CC[C@H](C)[C@@H]1[C@H](CC[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C. Product ID: ACM71827037-2. Alfa Chemistry ISO 9001:2015 Certified.
Ivermectin B1b
Ivermectin B1b is a minor component of Ivermectin, a semi-synthetic derivative of Abamectin. Ivermectin is a medication that is effective against many types of parasites. Synonyms: Dihydroavermectin B1b; 22,23-Dihydroavermectin B1b; Avermectin H2B1b. Grades: >95% by HPLC. CAS No. 70209-81-3. Molecular formula: C47H72O14. Mole weight: 861.06.
Ivermectin B1b
Ivermectin B1b is the minor component (>20%) of the commercial anthelmintic, ivermectin. Members of the avermectin/milbemycin anthelmintic class exert their anthelmintic effects by binding to glutamate-gated chloride channels expressed on nematode neurones and pharyngeal muscle cells. The avermectin/milbemycins are also potent insecticides. In vitro tests have found the B1b (25-iso-propyl) analogue to be slightly more potent than the 25-sec-butyl (B1a) analogue as an inhibitor of nematode larval development and paralysis and also a more sensitive probe for ivermectin resistance. Group: Biochemicals. Alternative Names: Ivermectin B1b, 22, 23-Dihydroavermectin B1b. Grades: Highly Purified. CAS No. 70209-81-3. Pack Sizes: 500ug, 2.5mg. US Biological Life Sciences.
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Ivermectin B1 monosaccharide
Ivermectin B1 monosaccharide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4'-O-De(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-O-demethyl-22,23-dihydro-avermectin A1a. Appearance: White to off-white solid. CAS No. 71837-27-9. Molecular formula: C41H62O11. Mole weight: 730.94. Purity: 0.98. IUPACName: (1R,4S,5'S,6R,6'R,8R,10Z,12S,13S,14Z,20R,21R,24S)-6'-[(2S)-butan-2-yl]-21,24-dihydroxy-12-[(2R,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one. Canonical SMILES: CC[C@H](C)[C@@H]1[C@H](CC[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(\[C@H]([C@H](/C=C\C=C4CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O)OC)/C)C. Product ID: ACM71837279. Alfa Chemistry ISO 9001:2015 Certified. Categories: Ivermectin B1a monosaccharide.
Ivermectin Impurity D
an impurity of Ivermectin. Synonyms: 28-Oxo Ivermectin B1a (Impurity); 5-O-Demethyl-22,23-dihydro-28-oxo-avermectin A1a; Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran] Avermectin A1a Deriv. Grades: > 95%. CAS No. 102190-55-6. Molecular formula: C48H72O15. Mole weight: 889.10.
Ivermectin Impurity H
an impurity of Ivermectin. Synonyms: Ivermectin B1 Mono-sugar Derivative; 4'-O-De(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-O-demethyl-22,23-dihydro-avermectin A1a; Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran] Avermectin A1a Deriv. Grades: > 95%. CAS No. 71837-27-9. Molecular formula: C41H62O11. Mole weight: 730.94.
Ivermectin Impurity K
an impurity of Ivermectin. Synonyms: 3,4-Dihydro Ivermectin (Mixture of Diastereomers) ; 5-O-Demethyl-3,4,22,23-tetrahydro-avermectin A1a; Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran] Avermectin A1a Deriv. Grades: > 95%. CAS No. 74567-01-4. Molecular formula: C48H76O14. Mole weight: 877.13.
Ivermectin monosaccharide
A semi-synthetic product produced by selective hydrolysis of the terminal saccharide unit. It is a potent inhibitor of nematode larval development, but is devoid of paralytic activity. It is a sensitive probe for the detection of some types of ivermectin resistance. An impurity of Ivermectin. Synonyms: Dihydroavermectin B1 monosaccharide; Ivermectin B1 monosaccharide; 4'-O-De(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-O-demethyl-22,23-dihydro-avermectin A1a; 4'-O-De(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)ivermectin B1. Grades: >99% by HPLC. CAS No. 123997-64-8. Molecular formula: C41H62O11. Mole weight: 730.92.
Jietacin A
Jietacin A is originally isolated from Str. sp. KP-197. It is found to be resistant to nematode, it can 100% kill Burs helenchus Lignicolus with the concentration of 0.25μg/mL, which is 10 times stronger than Avermectin B1a. Synonyms: Jietacine A; BRN 5538455; 1-(Ethenyl-ONN-azoxy)-14-methyl-8-pentadecanone. CAS No. 109766-61-2. Molecular formula: C18H34N2O2. Mole weight: 310.47.
Jietacin B
Jietacin B is originally isolated from Str. sp. KP-197. It is found to be resistant to nematode, it can 100% kill Burs helenchus Lignicolus with the concentration of 0.25μg/mL, which is 10 times stronger than Avermectin B1a. CAS No. 109766-62-3. Molecular formula: C19H36N2O2. Mole weight: 324.50.
Milbemycin A3
Milbemycins are a complex family of macrocyclic lactones containing a highly characteristic spiroketal group produced by Streptomyces hydroscopicus subsp. aureolarcrimosus. Milbemycin A3 is the dominant member of a group of analogues containing a 25-methyl substituent. Milbemycin A3 is a highly selective and potent nematocide and insecticide. Like the closely related avermectins, milbemycins are thought to act on chloride-gated ion channels. Related to: Avermectin B1a, Avermectin B1b, Milbemycin A4, Milbemycin D, Nemadectin. Group: Biochemicals. Alternative Names: (6R,25R)-5-O-Demethyl-28-deoxy-6,28-epoxy-25-methylmilbemycin B; Spiro [11, 15-methano-2H, 7H, 13H-furo [4, 3, 2-pq] [2, 6] benzodioxa cyclooctadecin-13, 2- [2H] pyran] , milbemycin B deriv.; (+)-Milbemycin α1; Antibiotic B 41A3; Emamectin A3; GWN 1725; Gowan 1725; Koromite; Matsuguard; Mesa; Mesa (acaricide); Milbeknock; Milbemectin; Milbemycin A3; Milbemycin α1; Ultiflora; Milbemycin EP Impurity B. Grades: Highly Purified. CAS No. 51596-10-2. Pack Sizes: 1mg. Molecular Formula: C??H??O?, Molecular Weight: 528.68. US Biological Life Sciences.
Worldwide
Milbemycin A4 (Antibiotic B 41A4, Milbemycin alpha3)
Milbemycins are a complex family of macrocyclic lactones containing a highly characteristic spiroketal group produced by Streptomyces hydroscopicus subsp. aureolarcrimosus. Milbemycin A4 is the dominant member of a group of analogues containing a 25-ethyl substituent. Milbemycin A4 is a highly selective and potent nematocide and insecticide. Like the closely related avermectins, milbemycins are thought to act on chloride-gated ion channels. Group: Biochemicals. Alternative Names: Antibiotic B 41A4, Milbemycin alpha3. Grades: Highly Purified. CAS No. 51596-11-3. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Milbemycin D (Antibiotic B 41D)
Milbemycins are a complex family of macrocyclic lactones containing a highly characteristic spiroketal group produced by Streptomyces hydroscopicus subsp. aureolarcrimosus. Milbemycin D is a minor member of a group of analogues containing a 25-isopropyl substituent. Milbemycin D is a highly selective and potent nematocide and insecticide. Like the closely related avermectin, milbemycins are thought to act on chloride-gated ion channels. Group: Biochemicals. Alternative Names: Antibiotic B 41D. Grades: Highly Purified. CAS No. 77855-81-3. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Milbemycin Oxime
Milbemycin oxime is a semi-synthetic macrocyclic lactone prepared by the oxidation and oximation of a mixture of two natural products, milbemycin A3 and A4 (in ~70: 30 ratio). Moxidectin oxime, marketed as Interceptor, is used therapeutically for the prevention of intestinal parasites in dogs. Like the other milbemycin / avermectins, it was developed for intestinal parasite control in animals and acts by opening glutamate sensitive chloride channels in neurons of invertebrates leading to paralysis by hyperpolarisation of these cells and signal transfer blocking. Group: Biochemicals. Grades: Highly Purified. CAS No. 129496-10-2. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
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