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1-?(2,?3,?5-?Tri-?O-?acetyl-? β-?D-?ribofuranosyl)?-?1,?2,?4-?triazole-?3-?carboxylic Acid Methyl Ester is a reactant used in the synthesis of azole nucleoside 5'-?MP mimics (P1Ms) as IMP dehydrogenase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 39925-10-5. Pack Sizes: 10mg, 100mg. Molecular Formula: C15H19N3O9, Molecular Weight: 385.33. US Biological Life Sciences.
As an IMP dehydrogenase inhibitor, 1-(2,?3,?5-Tri-O-acetyl-β-D-ribofuranosyl)?-1,?2,?4-triazole-3-carboxylic Acid Methyl Ester is a reactant used in the synthesis of azole nucleoside 5'-MP mimics (P1Ms). Synonyms: Methyl 1-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)?-1,2,4-triazole-3-carboxylate; 1-(2,3,5-Tri-O-acetyl-β-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxylic Acid Methyl Ester. Grade: 96%. CAS No. 39925-10-5. Molecular formula: C15H19N3O9. Mole weight: 385.33.
1-?(2,?3,?5-?Tri-?O-?acetyl-? β-?D-?ribofuranosyl)?-?1,?2,?4-?triazole-?3-?carboxylic Acid Methyl Ester-13C2 is the labeled analogue of 1-?(2,?3,?5-?Tri-?O-?acetyl-? β-?D-?ribofuranosyl)?-?1,?2,?4-?triazole-?3-?carboxylic Acid Methyl Ester (T767035), a reactant used in the synthesis of azole nucleoside 5'-?MP mimics (P1Ms) as IMP dehydrogenase inhibitors. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C1313C2H19N3O9, Molecular Weight: 387.31. US Biological Life Sciences.
As an IMP dehydrogenase inhibitor, 1-(2,?3,?5-Tri-O-acetyl-β-D-ribofuranosyl)?-1,?2,?4-triazole-3-carboxylic Acid Methyl Ester-13C2, the labeled analogue of 1-(2,?3,?5-Tri-O-acetyl-β-D-ribofuranosyl)?-1,?2,?4-triazole-3-carboxylic Acid Methyl Ester, is a reactant used in the synthesis of azole nucleoside 5'-MP mimics (P1Ms). Synonyms: Methyl 1-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)?-1,2,4-triazole-3-carboxylate-13C2. Molecular formula: C13[13C]2H19N3O9. Mole weight: 387.31.
1,2,4-Triazole Sodium Salt
1,2,4-Triazole Sodium Salt is an azole-based antimycotic agent that can be used to inhibit mold on unseasoned pine. Group: Biochemicals. Grades: Highly Purified. CAS No. 41253-21-8. Pack Sizes: 10g, 25g. Molecular Formula: C2H2N3Na. US Biological Life Sciences.
1-[[(2R,3S)-2-(2,4-Difluorophenyl)-3-methyloxiranyl]methyl]-1H-1,2,4-triazole is a useful intermediate for the synthesis of sulfur-containing antifungal azoles was synthesized. Group: Biochemicals. Grades: Highly Purified. CAS No. 127000-90-2. Pack Sizes: 500mg, 1g. Molecular Formula: C12H11F2N3O, Molecular Weight: 251.23. US Biological Life Sciences.
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1-Methyl-1,2,3-triazole
An azole compound used for binding affinity with various cytochrome P 450 (CYP) proteins. Group: Biochemicals. Grades: Highly Purified. CAS No. 16681-65-5. Pack Sizes: 1g, 5 g. Molecular Formula: C3H5N3, Molecular Weight: 83.09. US Biological Life Sciences.
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1-Methyl-1,2,4-triazole
An azole compound used for binding affinity with various cytochrome P 450 (CYP) proteins. Group: Biochemicals. Alternative Names: 1-Methyl-1H-1,2,4-triazole; 1-Methyltriazole. Grades: Highly Purified. CAS No. 6086-21-1. Pack Sizes: 5g. US Biological Life Sciences.
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4,5,6,7-Tetrabromo-1H-benzotriazole
4,5,6,7-Tetrabromo-1H-benzotriazole. Group: Biochemicals. Alternative Names: 4, 5, 6, 7-Tetrabromobenzotri azole; NSC 231634; TBB. Grades: Highly Purified. CAS No. 17374-26-4. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C6HBr4N3. US Biological Life Sciences.
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4, 5, 6, 7-Tetrabromobenzotri azole (TBB)
TBB is one of t. Group: Biochemicals. Alternative Names: TBB. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
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4-Methyl-3-nitropyrazole
4-Methyl-3-nitropyrazole is used in the synthesis of 4-(N-azolyl)-3,5-dinitropyrazoles. Group: Biochemicals. Alternative Names: 4-Methyl-3-nitro-1H-pyrazole. Grades: Highly Purified. CAS No. 38858-90-1. Pack Sizes: 25mg. US Biological Life Sciences.
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Aliconazole
An antifungal azole derivative. Synonyms: 1-[(Z)-2-(4-chlorophenyl)-3-(2,4-dichlorophenyl)prop-2-enyl]imidazole. CAS No. 63824-12-4. Molecular formula: C18H13Cl3N2. Mole weight: 363.67.
Fenticonazole Nitrate is an azole antifungal agent. Synonyms: ITF2357; ITF 2357; ITF-2357. Grade: >98%. CAS No. 73151-29-8. Molecular formula: C24H20Cl2N2OS·HNO3. Mole weight: 518.41.
Fosravuconazole
Fosravuconazole is an azole antifungal agent potentially for the treatment of fungal infections, as a water-soluble prodrug of ravuconazole that is being developed by the Drugs for Neglected Diseases Initiative (DNDi). Uses: A water-soluble prodrug of ravuconazole that is being developed by the drugs for neglected diseases initiative (dndi). Synonyms: Fosravuconazole; BEF-1224; BMS-379224; E-1224; BEF1224; BMS379224; E1224.[(2R,3R)-3-[4-(4-cyanophenyl)-1,3-thiazol-2-yl]-2-(2,4-difluorophenyl)-1-(1,2,4-triazol-1-yl)butan-2-yl]oxymethyl dihydrogen phosphate. Grade: ≥98%. CAS No. 351227-64-0. Molecular formula: C23H20F2N5O5PS. Mole weight: 547.09.
Luliconazole
Luliconazole is an azole antifungal drug. Its mechanism of action involves inhibition of ergosterol biosynthesis by inhibition of sterol 14α-demethylase. Group: Biochemicals. Alternative Names: [R-(E)]-α-[4-(2,4-Dichlorophenyl)-1,3-dithiolan-2-ylidene]-1H-imidazole-1-acetonitrile; Lulicon; NND 502. Grades: Highly Purified. CAS No. 187164-19-8. Pack Sizes: 500mg, 1g. Molecular Formula: C??H?Cl?N?S?, Molecular Weight: 354.28. US Biological Life Sciences.
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Mefentrifluconazole
Mefentrifluconazole is a novel azole derivative and used as an agrochemical broad-spectrum antifungal agent. Mefentrifluconazole is a potent, selective and orally active fungal CYP51 ( K d = 0.5 nM) inhibitor, but shows less inhibitory activity on human aromatase ( IC 50 =0.92 μM) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1417782-03-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136063.
Posaconazole
Anti-fungal agent; sterol α-demethylase inhibitor. Posaconazole is a highly potent broadspectrum antifungal drug. It blocks the synthesis of ergosterol by inhibiting of the enzyme lanosterol 14α-demethylase resulting in accumulation of methylated sterol precursors. In contrast to other antifungal azoles, posaconazole has been reported not to induce the efflux pump mechanism. Posaconazole was able to produce a parasitological cure in a mouse model of the chronic stage of Chagas disease. Group: Biochemicals. Alternative Names: 2, 5-Anhydro-1, 3, 4-trideoxy-2-C- (2, 4-difluorophenyl) -4- [ [4- [4- [4- [1- [ (1S, 2S) -1-ethyl-2-hydroxypropyl] -1, 5-dihydro-5-oxo-4H-1, 2, 4-triazol-4-yl] phenyl] -1-piperazinyl] phenoxy] methyl] -1- (1H-1, 2, 4-triazol-1-yl) -D-threo-pentitol; Noxafil; Sch 56592. Grades: Highly Purified. CAS No. 171228-49-2. Pack Sizes: 250mg, 500mg, 1g, 5g. Molecular Formula: C??H??F?N?O?, Molecular Weight: 700.78. US Biological Life Sciences.
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Secnidazole
Secnidazole (RP-14539) is an orally active azole antibiotic and a imidazole mitigator of Serratia marcescens virulence. Secnidazole, as an analog of acylhomoserine lactones, effectively inhibits QS resulting in the attenuation of Pseudomonas aeruginosa pathogenesis. Secnidazole has antimicrobial activity against many anaerobic Gram-negative and Gram-positive bacterial species in vitro. Secnidazole can be used for the research of various diseases, such as amoebiasis and giardiasis, and bacterial vaginitis [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RP-14539; PM-185184. CAS No. 3366-95-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-B1118.
(S)-Luliconazole
(S)-Luliconazole is the S-enantiomer of Luliconazole, an azole antifungal drug. Luliconazole was found to interfere with ergosterol biosynthesis in cell-free extracts of Candida albican, while no interference due to (S)-Luliconazole was found. Synonyms: (αE)-α-[(4S)-4-(2,4-Dichlorophenyl)-1,3-dithiolan-2-ylidene]-1H-imidazole-1-acetonitrile. Grade: > 95%. CAS No. 256424-63-2. Molecular formula: C14H9Cl2N3S2. Mole weight: 354.28.
Tebuconazole
Tebuconazole is an orally active agricultural azole fungicide which can also inhibit CYP51 with IC 50 s of 0.9 and 1.3 μM for Candida albicans CYP51 ( CaCYP51 ) and truncated Homo sapiens CYP51 ( Δ60HsCYP51 ), respectively. Tebuconazole induces lipid accumulation and oxidative stress in HepG2 Cells. Tebuconazole decreases MAC-T cells viability and proliferation, induces ER-stress-mediated apoptosis and increases oxidative stress levels in MAC-T cells [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. CAS No. 107534-96-3. Pack Sizes: 10 mM * 1 mL; 200 mg; 1 g. Product ID: HY-B0852.
Tebuconazole (Standard)
Tebuconazole (Standard) is the analytical standard of Tebuconazole. This product is intended for research and analytical applications. Tebuconazole is an orally active agricultural azole fungicide which can also inhibit CYP51 with IC 50 s of 0.9 and 1.3 μM for Candida albicans CYP51 ( CaCYP51 ) and truncated Homo sapiens CYP51 ( Δ60HsCYP51 ), respectively. Tebuconazole induces lipid accumulation and oxidative stress in HepG2 Cells. Tebuconazole decreases MAC-T cells viability and proliferation, induces ER-stress-mediated apoptosis and increases oxidative stress levels in MAC-T cells [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. CAS No. 107534-96-3. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0852R.
(Z)-rac-Luliconazole
(Z)-rac-Luliconazole is a stereoisomer of Luliconazole which is an azole antifungal drug. Synonyms: (Z)-α-[4-(2,4-Dichlorophenyl)-1,3-dithiolan-2-ylidene]-1H-imidazole-1-acetonitrile. Grade: > 95%. CAS No. 101529-76-4. Molecular formula: C14H9Cl2N3S2. Mole weight: 354.28.
1,2,4-Triazol-4-amine
1,2,4-Triazol-4-amine is an intermediate used to prepare potent, selective, and orally active cyclooxygenase-?2 inhibitors. It is also used to synthesize hydroxyphenacyl azoles and related azolium derivatives as antifungal agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 584-13-4. Pack Sizes: 1g, 10 g. Molecular Formula: C2H4N4. US Biological Life Sciences.
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1-Bromo-2,4-difluorobenzene
1-Bromo-2,4-difluorobenzene is a reactant used in the preparation of azole derivatives as highly-selective fungal CYP51 inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 348-57-2. Pack Sizes: 5g, 10g. Molecular Formula: C6H3BrF2, Molecular Weight: 192.99. US Biological Life Sciences.
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2-(2H-Benzotriazol-2-yl)-4,6-di-tert-pentylphenol
2-(2H-Benzotriazol-2-yl)-4,6-di-tert-pentylphenol is an ultraviolet light absorber (UVA) of the hydroxyphenylbenzotri azole class, which imparts outstanding light stability to plastics and other organic substrates. Group: Biochemicals. Grades: Highly Purified. CAS No. 25973-55-1. Pack Sizes: 1g, 5g. Molecular Formula: C22H29N3O. US Biological Life Sciences.
Isotope labelled 2-(2H-Benzotriazol-2-yl)-4,6-di-tert-pentylphenol is an ultraviolet light absorber (UVA) of the hydroxyphenylbenzotri azole class, which imparts outstanding light stability to plastics and other organic substrates. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C22H17D12N3O, Molecular Weight: 363.56. US Biological Life Sciences.
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[2-(4-Fluorophenyl)thiazol-4-yl]methanol
[2-(4-Fluorophenyl)thiazol-4-yl]methanol is an intermediate used in preparation of azole compounds as histone deacetylase (HDAC) inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 885280-13-7. Pack Sizes: 100mg, 250mg. Molecular Formula: C10H8FNOS, Molecular Weight: 209.24. US Biological Life Sciences.
2, 5-Anhydro-1, 3, 4-trideoxy-2-C- (2, 4-difluorophenyl)-4- (hydroxymethyl)-1- (1H-1, 2, 4-triazol-1-yl)-D-threo-pentitol is building block to synthesize key intermediates towards synthesis of highly active azole antifungals Sch 51048, Sch 56592 and Sch 45012. It is also an impurity/intermediate for posaconazole (P689600). Group: Biochemicals. Grades: Highly Purified. CAS No. 160709-02-4. Pack Sizes: 500mg, 1 g. Molecular Formula: C14H15F2N3O2. US Biological Life Sciences.
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2-Bromo-1,3-cyclohexanedione
2-Bromo-1,3-cyclohexanedione is an starting material in the synthesis of azole derivatives as histamine H3 receptor antagonists. Group: Biochemicals. Grades: Highly Purified. CAS No. 60060-44-8. Pack Sizes: 1g. US Biological Life Sciences.
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2-Bromo-1H-pyrrole
2-Bromo-1H-pyrrole can be used as reactant/reagent in preparation and structure-activity relationship of trifluoroalkyl-containing azoles and arenes as inhibitors of β-amyloid self-assembly. Group: Biochemicals. Grades: Highly Purified. CAS No. 38480-28-3. Pack Sizes: 100mg, 250mg. Molecular Formula: C4H4BrN, Molecular Weight: 145.99. US Biological Life Sciences.
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2-Fluoro-4-pyrrolidinobenzoic Acid
2-Fluoro-4-pyrrolidinobenzoic Acid acts as a reagent in the preparation of amido-substituted azole compounds as TNKS1 and TNKS2 inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 1197193-14-8. Pack Sizes: 100mg, 250mg. Molecular Formula: C11H12FNO2, Molecular Weight: 209.22. US Biological Life Sciences.
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3-(1H-1,2,4-Triazol-1-yl)propanenitrile
3-(1H-1,2,4-Triazol-1-yl)propanenitrile acts as a reagent in the synthesis of hydroxyphenacyl azoles and related azolium derivatives as antifugal agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 76686-83-4. Pack Sizes: 500mg, 1g. Molecular Formula: C5H6N4, Molecular Weight: 122.13. US Biological Life Sciences.
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3-Benzotriazol-1-yl-propionic Acid
3-Benzotriazol-1-yl-propionic Acid is used in biological studies of azole derivatives as a novel non-iron-chelating inhibitors of prolyl hydroxylase 3 for HIF-1 activation. Group: Biochemicals. Grades: Highly Purified. CAS No. 654-15-9. Pack Sizes: 250mg, 1g. Molecular Formula: C9H9N3O2, Molecular Weight: 191.19. US Biological Life Sciences.
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4-Nitrobenzyl Bromide
4-Nitrobenzyl Bromide is used in the synthesis of di and tri-substituted azoles. Also used in the preparation of N6-Benzyladenosine-5-uronamides as selective A3 adenosine agonists. Group: Biochemicals. Alternative Names: 1-(Bromomethyl)-4-nitrobenzene; α-Bromo-p-nitro-toluene; 1-(Bromomethyl)-4-nitrobenzene; 4- (Bromomethyl) nitrobenzene; 4-Nitrobenzyl Bromide; 4-Nitrophenylmethyl Bromide; NSC 4609; p- (Bromomethyl) nitrobenzene; p-Nitro-α-bromotoluene; p-Nitrobenzyl Bromide; α-Bromo-4-nitrotoluene; α-Bromo-p-nitrotoluene. Grades: Highly Purified. CAS No. 100-11-8. Pack Sizes: 10g. US Biological Life Sciences.
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4-Vinylbenzyl Bromide (stabilized with TBC)
4-Vinylbenzyl Bromide is a useful synthetic intermediate. It is used to synthesize oxime-containing azole derivatives with antifungal activities. It is also used to prepare photo-resist polymers. Group: Biochemicals. Grades: Highly Purified. CAS No. 13368-25-7. Pack Sizes: 100mg, 1g. Molecular Formula: C9H9Br, Molecular Weight: 197.07. US Biological Life Sciences.
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Azamulin
Azamulin is an azole derivative of pleuromutilin. Azamulin is a highly selective inhibitor of cytochrome P450 3A4 (CYP3A4). Synonyms: Azamulinum. Grade: >99% by HPLC. CAS No. 76530-44-4. Molecular formula: C24H36N4O4S. Mole weight: 476.63.
Bacteriocin microcin B17
Bacteriocin microcin B17 is an antimicrobial peptide produced by Escherichia coli. It has antimicrobial activity. MccB17 was the first compound discovered from the Thiazole/Oxazole-Modified Microcins (TOMMs) family and the Linear Azole-containing peptides (LAPs). These ribosomal peptides are post-translationally modified to convert serine and cysteine residues into oxazole and thiazole rings. Synonyms: mcbA; MccB17. Grade: >98%.
BMS 309403
BMS 309403 is a potent, selective and cell-permeable inhibitor of adipocyte fatty acid binding protein (FABP4) with a Ki of less than 2 nM, which exhibits Ki values of 250 nM for FABP3 and 350 nM for FABP5. BMS 309403 interacts with the fatty-acid-binding pocket within the interior of the protein and competitively inhibits the binding of endogenous fatty acids. BMS 309403 is a biphenyl azole inhibitor against fatty acid binding protein 4 (FABP4) and regarded as a lead compound for effective treatment of obesity related cardio-metabolic diseases. Synonyms: BMS-309403; BMS309403; Adipocyte FABP Inhibitor; A-FABP Inhibitor; ALBP Inhibitor; aP2 Inhibitor; FABP4 Inhibitor; Fatty Acid Binding Protein 4 Inhibitor. Grade: ≥98%. CAS No. 300657-03-8. Molecular formula: C31H26N2O3. Mole weight: 474.55.
Cyclopropylmethyl Bromide
Cyclopropylmethyl Bromide is a reagent used in the synthesis of human dihydroorotate dehydrogensase inhibitors which are based on azole scaffolds. In addition it is used in the preparation of ([11C]CMDC) for PET imaging of mGlur2 which has been a proposed target in the treatment of schizophrenia. Group: Biochemicals. Grades: Highly Purified. CAS No. 7051-34-5. Pack Sizes: 1g, 5g, 10g, 50g, 100g. Molecular Formula: C?H?Br. US Biological Life Sciences.
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Germacrene D
Germacrene D is isolated from Solidago canadensis. Germacrene D has antibacterial and antifungal activities and can be used as an adjuvant agent in the application of aminoglycosides and azoles [1]. Uses: Scientific research. Group: Natural products. CAS No. 23986-74-5. Pack Sizes: 250 μg (4.89 mM * 250 μL in Heptane); 500 μg (4.89 mM * 500 μL in Heptane); 1 mg (4.89 mM * 1 mL in Heptane). Product ID: HY-125685.
iKIX1
iKIX1 is an inhibitor of Pdr1-dependent gene activation. It re-sensitizes drug-resistant C. glabrata to azole antifungals in vitro and in amnimal models. Synonyms: 2-Cyano-N-{[(3,4-dichlorophenyl)carbamothioyl]amino}acetamide. CAS No. 656222-54-7. Molecular formula: C10H8Cl2N4OS. Mole weight: 303.2.
Papulacandin A
It is produced by the strain of Papularia sphaerosperma. It has strong anti-yeast effect, but no effect on filiform fungi, bacteria and protozoa. It has no cross-resistance with polyene antibiotics, Conocandin and azole antifungal chemotherapy drugs, but has partial cross-resistance with Echinocandin B. Among the four components, Papulacandin C has the strongest activity and Papulacandin D has the weakest activity. Synonyms: 1,1-O-(4,6-Dihydroxy-1,2-phenylenemethylene)-4-O-[6-O-(1-oxo-2,4-decadienyl)-β-D-galactopyranosyl]-α-D-glucopyranose3-(7-hydroxy-8,14-dimethylhexadeca-2,4,8,10-tetraenoate); β-D-Galactopyranoside, (1S,3'R,4'R,5'R,6'R)-3',4',5',6'-tetrahydro-3',5,7-trihydroxy-4'-[(7-hydroxy-8,14-dimethyl-1-oxo-2,4,8,10-hexadecatetraenyl)oxy]-6'-(hydroxymethyl)spiro[isobenzofuran-1(3H),2'-[2H]pyran]-5'-yl,6-(2,4-decadienoate). CAS No. 61036-46-2. Molecular formula: C47H66O16. Mole weight: 887.02.
Papulacandin B
It is produced by the strain of Papularia sphaerosperma. It has strong anti-yeast effect, but no effect on filiform fungi, bacteria and protozoa. It has no cross-resistance with polyene antibiotics, Conocandin and azole antifungal chemotherapy drugs, but has partial cross-resistance with Echinocandin B. Among the four components, Papulacandin C has the strongest activity and Papulacandin D has the weakest activity. The mechanism of B is to inhibit the synthesis of glucan in yeast cell wall. Synonyms: alpha-D-Glucopyranose, 1,16-anhydro-1-C-(2,4-dihydroxy-6-(hydroxymethyl)phenyl)-4-O-(6-O-(8-hydroxy-1-oxo-2,4,6-decatrienyl)-beta-D-galactopyranosyl)-, 3-(7-hydroxy-8,14-dimethyl-2,4,8,10-hexadecatetraenoate); β-D-Galactopyranoside, (1S,3'R,4'R,5'R,6'R)-3',4',5',6'-tetrahydro-3',5,7-trihydroxy-4'-[[(2E,4E,8E,10E)-7-hydroxy-8,14-dimethyl-1-oxo-2,4,8,10-hexadecatetraen-1-yl]oxy]-6'-(hydroxymethyl)spiro[isobenzofuran-1(3H),2'-[2H]pyran]-5'-yl,6-[(2E,4Z,6E)-8-hydroxy-2,4,6-decatrienoate]. CAS No. 61032-80-2. Molecular formula: C47H64O17. Mole weight: 901.00.
Papulacandin C
It is produced by the strain of Papularia sphaerosperma. It has strong anti-yeast effect, but no effect on filiform fungi, bacteria and protozoa. It has no cross-resistance with polyene antibiotics, Conocandin and azole antifungal chemotherapy drugs, but has partial cross-resistance with Echinocandin B. Among the four components, Papulacandin C has the strongest activity and Papulacandin D has the weakest activity. Synonyms: (1S,3'R,4'R,5'R,6'R)-3',5,7-trihydroxy-5'-({6-O-[(2E,4E,6E)-8-hydroxydeca-2,4,6-trienoyl]-beta-D-galactopyranosyl}oxy)-6'-(hydroxymethyl)-3',4',5',6'-tetrahydro-3H-spiro[2-benzofuran-1,2'-pyran]-4'-yl (2E,4E,7S,8E,10E,14S)-7-hydroxy-8,14-dimethylhexadeca-2,4,8,10-tetraenoate; 1,1-O-(4,6-Dihydroxy-1,2-phenylenemethylene)-4-O-[6-O-[(2E,4E,6E)-1-oxo-8-hydroxy-2,4,6-decatrienyl]-beta-D-galactopyranosyl]-alpha-D-glucopyranose 3-[(2E,4E,7S,8E,10E,14S)-7-hydroxy-8,14-dimethylhexadeca-2,4,8,10-tetraenoate]. CAS No. 61036-48-4. Molecular formula: C47H64O17. Mole weight: 901.00.
Papulacandin D
It is produced by the strain of Papularia sphaerosperma. It has strong anti-yeast effect, but no effect on filiform fungi, bacteria and protozoa. It has no cross-resistance with polyene antibiotics, Conocandin and azole antifungal chemotherapy drugs, but has partial cross-resistance with Echinocandin B. Among the four components, Papulacandin C has the strongest activity and Papulacandin D has the weakest activity. Synonyms: (+)-papulacandin D; (1S,3'R,4'S,5'R,6'R)-3',5,5',7-tetrahydroxy-6'-(hydroxymethyl)-3',4',5',6'-tetrahydro-3H-spiro[2-benzofuran-1,2'-pyran]-4'-yl (2E,4E,7S,8E,10E,14S)-7-hydroxy-8,14-dimethylhexadeca-2,4,8,10-tetraenoate. CAS No. 61036-49-5. Molecular formula: C31H42O10. Mole weight: 574.66.
PC945
PC945, a potent, long-acting antifungal triazole, possesses activity against a broad range of both azole-susceptible and azole-resistant strains of Aspergillus fumigatus. PC945 is also a potent, tightly binding inhibitor of A. fumigatus sterol 14α-demethylase activity, CYP51A and CYP51B , with IC 50 s of 0.23 μM and 0.22 μM, respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1931946-73-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-117766.
Pseurotin A is a secondary metabolite of Aspergillus. It has effective neurogenesis activity in PC12 pheochromocytoma cells, induces multipolar and branched neurites equivalent to β-NGF (an endogenous neurotrophic factor), and also exhibits chitinase inhibition. And it has a synergistic effect with azole antifungal agents. Synonyms: Pseurotin. Grade: >99% by HPLC. CAS No. 58523-30-1. Molecular formula: C22H25NO8. Mole weight: 431.43.
Pseurotin A
Pseurotin A is a fungal metabolite with an unusual hetero-spirocyclic ring system. It has been shown to have potent neuritogenic activity in PC12 phaechromocytoma cells, a useful model for adrenergic neuronal differentiation. Pseurotin A induced multipolar and branching neurites comparable to beta-NGF, an endogenous neurotrophic factor. Pseurotin A is also reported to exhibit chitinase inhibition and displays synergistic activity with azole antifungal agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 58523-30-1. Pack Sizes: 1mg. US Biological Life Sciences.
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10-Acetylphenothiazine
10-Acetylphenothiazine has been studied as a possible redox shuttle additive for chemical overcharge and overdischarge protection for lithium-ion batteries. It was used as a reagent in the synthesis of tri azolopyridinyl phenothiazines which displayed significant antibacterial and antifungal activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 1628-29-1. Pack Sizes: 1g, 2.5g. Molecular Formula: C14H11NOS, Molecular Weight: 241.31. US Biological Life Sciences.
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1-(4-Fluoro-2-hydroxy-5-methylphenyl)ethan-1-one
1-(4-Fluoro-2-hydroxy-5-methylphenyl)ethan-1-one aids in the discovery and optimization of Chromenotri azolopyrimidines as a potent inhibitor of the MDM2-p53 protein-protein interaction. Group: Biochemicals. Grades: Highly Purified. CAS No. 1196202-75-1. Pack Sizes: 100mg, 250mg. Molecular Formula: C9H9FO2, Molecular Weight: 168.16. US Biological Life Sciences.
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1-(4-Phenoxyphenyl)-1H-pyrrole-2,5-dione
1-(4-Phenoxyphenyl)-1H-pyrrole-2,5-dione. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CHEMBL2376207, 1-(4-phenoxyphenyl)pyrrole-2,5-dione, 1-(4-Phenoxy-phenyl)-pyrrole-2,5-dione, 1-(4-Phenoxyphenyl)-1H-pyrrole-2,5-dione, 1H-Pyrrole-2,5-dione, 1-(4-phenoxyphenyl)-, 1-(4-phenoxyphenyl)azoline-2,5-dione, 69422-82-8, ZINC00186463, AC1LBDCB, AC1Q6DOX, SureCN3675014, CBDivE_005983, CTK1J1113, MolPort-000-158-172, SBB082508, STK248729, AKOS000116633, AG-A-15110, AG-A-15113, MCULE-8533133623. Product Category: Heterocyclic Organic Compound. CAS No. 69422-82-8. Molecular formula: C16H11NO3. Mole weight: 265.27. Purity: 0.96. IUPACName: 1-(4-phenoxyphenyl)pyrrole-2,5-dione. Canonical SMILES: C1=CC=C(C=C1)OC2=CC=C(C=C2)N3C(=O)C=CC3=O. Product ID: ACM69422828. Alfa Chemistry ISO 9001:2015 Certified.
1-Boc-4- (2, 4-difluorobenzyl) piperazine
1-Boc-4- (2, 4-difluorobenzyl) piperazine is used as a reactant in the preparation of pyrrolotri azolopyrimidine derivatives as adenosine A2A receptor antagonists for treating adenosine A2A receptor-mediated diseases. Group: Biochemicals. Grades: Highly Purified. CAS No. 1065586-31-3. Pack Sizes: 100mg, 250mg. Molecular Formula: C16H22F2N2O2, Molecular Weight: 312.35. US Biological Life Sciences.
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1-Chloro-3-[(1-methylethyl)amino]-2-propanol
1-Chloro-3-[(1-methylethyl)amino]-2-propanol acts as a reagent in the preparation of isothiazolo[5,4-d]pyrimidine derivatives as antitumor agents, preparation of tri azoly thiopropanolamines as potential cardiovascular agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 50666-68-7. Pack Sizes: 100mg, 250mg. Molecular Formula: C6H14ClNO, Molecular Weight: 151.63. US Biological Life Sciences.
Worldwide
2,2,5,5-Tetramethylimidazolidin-4-one
2,2,5,5-Tetramethylimidazolidin-4-one. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2,2,5,5-TETRAMETHYLIMIDAZOLIDIN-4-ONE;2,2,5,5-tetramethylimid azolidin-one;TETRAMETHYLIMIDAZOLIDINE. Product Category: Heterocyclic Organic Compound. CAS No. 16256-42-1. Molecular formula: C7H14N2O. Mole weight: 142.2. Product ID: ACM16256421. Alfa Chemistry ISO 9001:2015 Certified.
2-Chloromethylbenzoic Acid
2-Chloromethylbenzoic Acid acts as a reagent for the synthesis of (azolyl) methyl) arylbenzamides as dual inhibitors of VEGFR-1/2 kinases. Group: Biochemicals. Grades: Highly Purified. CAS No. 85888-81-9. Pack Sizes: 500mg, 1g. Molecular Formula: C8H7ClO2, Molecular Weight: 170.59. US Biological Life Sciences.
(2R,3S,4R,5R)-2-Azido-2-((benzoyloxy)methyl)-5-(2-oxo-4-(1H-1,2,4-triazol-1-yl)pyrimidin-1(2H)-yl)tetrahydrofuran-3,4-diyl dibenzoate, a complex chemical compound, serves as a vital pharmaceutical intermediate essential for synthesizing potent nucleotide analogs with anti-cancer and anti-viral properties. Its utility compels us to leverage this intricate compound in the synthesis of efficacious drugs that can molecularly act against formidable cellular mechanisms, shielding us against devastating illnesses, and offering a new vista of life-prolonging therapeutic alternatives. Synonyms: (2R,3S,4R,5R)-2-azido-2-((benzoyloxy)methyl)-5-(2-oxo-4-(1H-1,2,4-tri(Azol-1-yl)pyrimidine 1(2H)-yl)tetrahydrofuran-3,4-diyl dibenzoate. Grade: 95%. Molecular formula: C32H24N8O8. Mole weight: 648.58.
2-(S)-Isobutyl-pyrrolidine Hydrochloride
2-(S)-Isobutyl-pyrrolidine Hydrochloride can be prepared from asymmetric synthesis of pyrrolidines from benzotri azolyl phenyl oxazolopyrrolidine via allylation, alkylation, and phosphorylation. (R)-isomer of (R)?-2-?(2-?Methylpropyl)?-pyrrolidine (M330115). Group: Biochemicals. Grades: Highly Purified. CAS No. 222314-40-1. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C8H17N; HCl, Molecular Weight: 127.233645999999. US Biological Life Sciences.
3-(5-(3-Nitrobenzoyl)-1,3-dioxoisoindolin-2-yl)benzoic acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: STK391547, 3-(5-(3-nitrobenzoyl)-1,3-dioxoisoindolin-2-yl)benzoic acid, 295348-05-9, AC1MJGEY, PubChem15946, BAS 00119373, Oprea1_095616, Oprea1_721524, MLS000714436, MolPort-001-915-305, HMS2766I24, AKOS000733342, MCULE-3139836716, SMR000274415, ST50217182, SR-01000360756, SR-01000360756-3, 3-[5-(3-nitrobenzoyl)-1,3-dioxoisoindol-2-yl]benzoic acid, 3-{5-[(3-nitrophenyl)carbonyl]-1,3-dioxobenzo[c]azolin-2-yl}benzoic acid, 3-[5-(3-Nitro-benzoyl)-1,3-dioxo-1,3-dihydro-isoindol-2-yl]-benzoic acid. Product Category: Heterocyclic Organic Compound. CAS No. 295348-05-9. Molecular formula: C22H12N2O7. Mole weight: 416.339880 [g/mol]. Purity: 0.96. IUPACName: 3-[5-(3-nitrobenzoyl)-1,3-dioxoisoindol-2-yl]benzoic acid. Canonical SMILES: C1=CC(=CC(=C1)N2C(=O)C3=C(C2=O)C=C(C=C3)C(=O)C4=CC(=CC=C4)[N+](=O)[O-])C(=O)O. Product ID: ACM295348059. Alfa Chemistry ISO 9001:2015 Certified.
3-[ (Trifluoromethyl) thio]phenol
3-[ (Trifluoromethyl) thio]phenol is a reactant used in the preparation of 2-azolyl-4-phenoxypyrimidines as highly active herbicides that inhibit carotenoid biosynthesis. Group: Biochemicals. Grades: Highly Purified. CAS No. 3823-40-3. Pack Sizes: 50mg, 500mg. Molecular Formula: C7H5F3OS, Molecular Weight: 194.17. US Biological Life Sciences.
Brotizolam derivative; a thienotri azolodiazepines as platelet activating factor antagonist. Group: Biochemicals. Alternative Names: Methyl 2-[4-(2-Chlorophenyl)-9-methyl-6H-thieno[3,2-f][1,2,4]thiazolo[4,3-a][1,4]diaze-pin-2-yl]ethane-1-carboxylate; Desbromo Brotizolam 2-Propanoic Acid Methyl Ester. Grades: Highly Purified. CAS No. 100827-83-6. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
4-Buthyl-1,2-diphenyl-3,5-dioxopyrazolidine
4-Buthyl-1,2-diphenyl-3,5-dioxopyrazolidine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: A 7514; Uzone; Buzon; pyrazinobutazone; Azolid; 4-Butyl-1,2-diphenylpyrazolidine-3,5-dione; Phenylbutazone; PBZ; Azdid; 4-butyl-1,2-diphenyl-3,5-pyrazolidinedione; Reudo; Butoz; Bute; 1,2-diphenyl-4-butyl-3,5-dioxopyrazolidine; 4-Butyl-1,2-diphenyl-3,5-py. Product Category: Heterocyclic Organic Compound. Appearance: off-white powder. CAS No. 50-33-0. Molecular formula: C19H20N2O2. Mole weight: 308.374. Purity: 0.96. IUPACName: phenylbutazone. Density: 1.173g/cm³. Product ID: ACM50330. Alfa Chemistry ISO 9001:2015 Certified.
4-Methylaminophenol Sulfate (Metol)
Metol is the hemisulfate salt of 4-Hydroxy-N-methylaniline, used to synthesize arylidene amino azolones with anticancer activity. It is also used to prepare N- (4-hydroxyphenyl) retinamide analogs with antitumor and apoptosis-inducing activities. Group: Biochemicals. Alternative Names: 4-(Methylamino)-phenol Sulfate (2:1) (salt); p-(Methylamino)-phenol Sulfate (2:1) (salt); 4-(Methylamino)phenol Sulfate (2:1) Salt; Armol Elon; Elon (developer); Genol; Graphol; Metatyl; Metol; N-Methyl-4-hydroxyaniline hemisulfate; N-Methyl-p-aminophenol sulfate; N-Methyl-p-aminophenol sulfuric acid hemisalt; N-Methyl-p-aminophenol sulfuric acid salt (2:1);Photol; Pictol; Planetol; Rhodol; p-Methylaminophenol Sulfate; p-Methylaminophenol Sulphate (2:1). Grades: Highly Purified. CAS No. 55-55-0. Pack Sizes: 100g, 250g, 500g. Molecular Formula: C??H??N?O?S. US Biological Life Sciences.
Worldwide
5-Amino-2-cyclopropyl-1H-isoindole-1,3(2H)-dione
5-Amino-2-cyclopropyl-1H-isoindole-1,3(2H)-dione. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SBB017898, 5-AMINO-2-CYCLOPROPYL-1H-ISOINDOLE-1,3(2H)-DIONE, 307990-29-0, 5-amino-2-cyclopropylbenzo[c]azoline-1,3-dione, SureCN2657805, CTK4G5939, MolPort-006-014-762, ZINC19092516, AKOS009207684, AG-F-02015, MCULE-5249524042, ST45028746. Product Category: Heterocyclic Organic Compound. CAS No. 307990-29-0. Molecular formula: C11H10N2O2. Mole weight: 202.209300 [g/mol]. Purity: 0.96. IUPACName: 5-amino-2-cyclopropylisoindole-1,3-dione. Density: 1.535g/cm³. Product ID: ACM307990290. Alfa Chemistry ISO 9001:2015 Certified.
Azolitmin
1g Pack Size. Group: Analytical Reagents, Stains & Indicators. Formula: C10H11N3O. CAS No. 1395-18-2. Prepack ID 90028378-1g. Molecular Weight 189.21. See USA prepack pricing.
Azolitmin
Azolitmin. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AZOLITMIN. Product Category: Heterocyclic Organic Compound. CAS No. 1395-18-2. Molecular formula: C10H11N3O. Mole weight: 189.21. Product ID: ACM1395182. Alfa Chemistry ISO 9001:2015 Certified.
Benzotri azol-1-yl-oxytri pyrrolidinphosphonium Hexafluorophosphate. Group: Biochemicals. Grades: Highly Purified. CAS No. 128625-52-5. Pack Sizes: 5g, 25g, 100g, 250g, 500g. Molecular Formula: C??H??F?N?OP?, Molecular Weight: 520.39. US Biological Life Sciences.
Worldwide
Cefazolin-[13C2,15N]
Cefazolin is an antibiotic used to treat a wide variety of bacterial infections. It may also be used before and during certain surgeries to help prevent infection. Cefazolin is a semisynthetic cephalosporin analog which attains high serum levels and is excreted quickly via the urine. Cefazolin-13C2,15N is intended for use as an internal standard for the quantification of cefazolin by GC- or LC-MS. Synonyms: [13C2,15N]-Cefazolin; Atirin-13C2,15N; Cefazina-13C2,15N; Azolin-13C2,15N; Biazolina-13C2,15N; Bor-Cefazol-13C2,15N; Cefacidal-13C2,15N; Cefamedin-13C2,15N; Cefazil-13C2,15N. Grade: ≥95%. CAS No. 2101505-58-0. Molecular formula: C12[13C]2H14N7[15N]O4S3. Mole weight: 457.5.
Cefazolin sodium salt
Cefazolin sodium salt. Group: Biochemicals. Alternative Names: (6R,7R)-3-[[(5-Methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-7-[(1H-tetrazol-1-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt; Atirin; Azolin. Grades: Highly Purified. CAS No. 27164-46-1. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C14H13N8NaO4S3. US Biological Life Sciences.
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