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| Product | Description | |
|---|---|---|
| 1-(3-Bromopropyl)-1,3-dihydro-2H-benzimidazol-2-one | 1-(3-Bromopropyl)-1,3-dihydro-2H-benzimidazol-2-one. Group: Biochemicals. Grades: Highly Purified. CAS No. 103784-04-9. Pack Sizes: 100mg. Molecular Formula: C10H11BrN2O, Molecular Weight: 255.11. US Biological Life Sciences. |  Worldwide |
| 1-(3-Bromopropyl)-1,3-dihydro-3-(1-methylethenyl)-2H-benzimidazol-2-one | 1-(3-Bromopropyl)-1,3-dihydro-3-(1-methylethenyl)-2H-benzimidazol-2-one is an intermediate in the synthesis of Domperidone (D531100), a novel peripheral dopamine receptor antagonist that does not cross the blood-brain barrier. Group: Biochemicals. Grades: Highly Purified. CAS No. 864267-63-0. Pack Sizes: 100mg, 1g. Molecular Formula: C13H15BrN2O. US Biological Life Sciences. | Worldwide |
| 1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazole-2-one | 1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazole-2-one. Group: Biochemicals. Grades: Highly Purified. CAS No. 62780-89-6. Pack Sizes: 100g, 250g, 500g, 1kg, 2kg. Molecular Formula: C10H11ClN2O. US Biological Life Sciences. | Worldwide |
| 1,3-Dihydro-1-(1,2,3,6-tetrahydro-4-pyridinyl)-2H-benzimidazol-2-one | 1,3-Dihydro-1-(1,2,3,6-tetrahydro-4-pyridinyl)-2H-benzimidazol-2-one is a reactant used in the synthesis of potential anti-parkinsonic agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 2147-83-3. Pack Sizes: 250mg, 500mg. Molecular Formula: C12H13N3O, Molecular Weight: 215.25. US Biological Life Sciences. | Worldwide |
| 1,3-Dihydro-1-[1-[(4-methyl-4H,6H-pyrrolo[1,2-a][4,1]benzoxazepin-4-yl)methyl]-4-piperidinyl]-2H-benzimidazol-2-one | Heterocyclic Organic Compound. Alternative Names: Zaldaride, Zaldaride maleate, Zaldaride [INN], Cgs 9343B, UNII-GH66PET6S3, CGS-9343B, C26H28N4O2, Zy 17617B, Zy-17617B, 109826-27-9 (maleate), CID65909, KW-6517, NCGC00159544-01, LS-172102, (+-)-1-(1-((4-Methyl-4H,6H-pyrrolo(1,2-a)(4,1)benzoxazepin-4-yl)methyl)-4-piperidyl)-2-benzimidazolinone, (+-)-1-(1-((4-Methyl-4H,6H-pyrrolo(1,2-alpha)(4,1)benzoxazepin-4-yl)methyl)-4-piperidyl)-2-benzimidazolinone, 1,3-dihydro-1-(1-((4-methyl-4H,6H-pyrrolo(1,2a)(4,1)-benzoxazepin-4-yl)methyl)-4-piperidinyl)-2H-benzimidazol-2-one, 109826-26-8. CAS No. 109826-26-8. Molecular formula: C26H28N4O2. Mole weight: 428.526120 [g/mol]. Purity: 0.96. IUPACName: 3-[1-[(4-methyl-6H-pyrrolo[1,2-a][4,1]benzoxazepin-4-yl)methyl]piperidin-4-yl]-1H-benzimidazol-2-one. Canonical SMILES: CC1 (C2=CC=CN2C3=CC=CC=C3CO1)CN4CCC (CC4)N5C6=CC=CC=C6NC5=O. Density: 1.31g/cm³. Catalog: ACM109826268. |  |
| 1,3-Dihydro-1-[1-(phenylmethyl)-4-piperidinyl]-2H-benzimidazol-2-one | 1,3-Dihydro-1-[1-(phenylmethyl)-4-piperidinyl]-2H-benzimidazol-2-one is an intermediate in the synthesis of Pimozide (D453300), a D2 dopamine receptor antagonist. Group: Biochemicals. Grades: Highly Purified. CAS No. 16148-06-4. Pack Sizes: 1g, 5g. Molecular Formula: C19H21N3O. US Biological Life Sciences. | Worldwide |
| 1,3-Dihydro-1-[1-(phenylmethyl)-4-piperidinyl]-2H-benzimidazol-2-one-d5 | 1,3-Dihydro-1-[1-(phenylmethyl)-4-piperidinyl]-2H-benzimidazol-2-one-d5 is an isotope labelled intermediate in the synthesis of Pimozide (D453302), a D2 dopamine receptor antagonist. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C19H16D5N3O. US Biological Life Sciences. | Worldwide |
| 2H-Benzimidazol-2-one,1,3-dihydro-1-(propylamino)-(9ci) | Heterocyclic Organic Compound. Alternative Names: 2H-Benzimidazol-2-one,1,3-dihydro-1-(propylamino)-(9CI). CAS No. 102616-97-7. Molecular formula: C10H13N3O. Catalog: ACM102616977. | |
| 2H-Benzimidazol-2-one,1,3-dihydro-4-(1-methylethyl)-(9ci) | Heterocyclic Organic Compound. Alternative Names: 2H-Benzimidazol-2-one,1,3-dihydro-4-(1-methylethyl)-(9CI). CAS No. 103151-02-6. Molecular formula: C10H12N2O. Catalog: ACM103151026. | |
| 2H-Benzimidazol-2-one,1,3-dihydro-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]- | Heterocyclic Organic Compound. CAS No. 108929-47-1. Molecular formula: C13H19N3O3. Mole weight: 263.2924. Density: 1.32g/cm³. Catalog: ACM108929471. | |
| 2H-Benzimidazol-2-one,1,3-dihydro-4,6-dimethyl-(9CI) | Heterocyclic Organic Compound. Alternative Names: 2H-Benzimidazol-2-one,1,3-dihydro-4,6-dimethyl-(9CI). CAS No. 102308-68-9. Molecular formula: C9H10N2O. Catalog: ACM102308689. | |
| 2H-Benzimidazol-2-one,1-(ethylmethylamino)-1,3-dihydro-(9ci) | Heterocyclic Organic Compound. Alternative Names: 2H-Benzimidazol-2-one,1-(ethylmethylamino)-1,3-dihydro-(9CI). CAS No. 102616-90-0. Molecular formula: C10H13N3O. Catalog: ACM102616900. | |
| 3-[3-(2,3-Dihydro-2-oxo-1H-benzimidazol-1-yl)propyl] Domperidone (Domperidone Impurity D) | 3-[3-(2,3-Dihydro-2-oxo-1H-benzimidazol-1-yl)propyl] Domperidone (Domperidone Impurity D). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 5-Chloro-3-[3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]-1-[1-[3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one, 5-Chloro-3-[3-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)-propyl]-1-[1-[3-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)propyl]piperidin-4-yl]-1,3-dihydro-2H-benzimidazol-2-one,2H-Benzimidazol-2-one, 5-chloro-3-[3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]-1-[1-[3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]-4-piperidinyl]-1,3-dihydro-. CAS No. 1614255-34-3. IUPAC Name: 5-chloro-3-[3-(2-oxo-3H-benzimidazol-1-yl)propyl]-1-[1-[3-(2-oxo-3H-benzimidazol-1-yl)propyl]piperidin-4-yl]benzimidazol-2-one. Molecular Formula: C32H34ClN7O3. Mole Weight: 600.11. Catalog: APS1614255343. SMILES: Clc1ccc2N (C3CCN (CCCN4C (=O)Nc5ccccc45)CC3)C (=O)N (CCCN6C (=O)Nc7ccccc67)c2c1. Format: Neat. |  |
| 5-Amino-6-(1-pyrrolidinyl)-1,3-dihydro-2H-benzimidazol-2-one | Heterocyclic Organic Compound. Alternative Names: 1082550-33-1, 5-AMINO-6-(1-PYRROLIDINYL)-1,3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE, Ambcb4030892, CTK4A5923, MolPort-008-476-446, ZINC20198686, AKOS000297484, AG-D-24445, MCULE-2945562128, AK121749, KB-244594, 5-Amino-6-(pyrrolidin-1-yl)-1H-benzo[d]imidazol-2(3H)-one. CAS No. 1082550-33-1. Molecular formula: C11H14N4O. Mole weight: 218.255060 [g/mol]. Purity: 0.96. IUPACName: 5-amino-6-pyrrolidin-1-yl-1,3-dihydrobenzimidazol-2-one. Canonical SMILES: C1CCN(C1)C2=C(C=C3C(=C2)NC(=O)N3)N. Catalog: ACM1082550331. | |
| 5-Benzoyl-1,3-dihydro-2H-benzimidazol-2-one | 5-Benzoyl-1,3-dihydro-2H-benzimidazol-2-one. Group: Biochemicals. Alternative Names: 5-Benzoyl-2-benzimidazolinone. Grades: Highly Purified. CAS No. 21472-33-3. Pack Sizes: 1g. Molecular Formula: C14H10N2O2, Molecular Weight: 238.24. US Biological Life Sciences. | Worldwide |
| 5-Bromo-1,3-dihydro-benzimidazol-2-one | 5-Bromo-1,3-dihydro-benzimidazol-2-one. Group: Biochemicals. Alternative Names: 5-Bromo-1,3-dihydro-2H-benzimidazol-2-one. Grades: Highly Purified. CAS No. 39513-26-3. Pack Sizes: 250mg, 500mg, 1g. US Biological Life Sciences. | Worldwide |
| 5-Bromo-1,3-dihydro-benzimidazol-2-one ≥95% (HPLC) | 5-Bromo-1,3-dihydro-benzimidazol-2-one ≥95% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g. US Biological Life Sciences. | Worldwide |
| 5-Chloro-1,3-dihydro-1-(4-piperidinyl)-2H-benzimidazol-2-one 99+% | 5-Chloro-1,3-dihydro-1-(4-piperidinyl)-2H-benzimidazol-2-one 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g, 100g. US Biological Life Sciences. | Worldwide |
| 5-Chloro-6-(2,3-dichlorophenoxy)-1,3-dihydro-2H-benzimidazol-2-one | 5-Chloro-6-(2,3-dichlorophenoxy)-1,3-dihydro-2H-benzimidazol-2-one is a metabolite of Triclabendazole, the only anthelmintic drug, which is active against immature, mature and adult stages of fluke. Group: Biochemicals. Alternative Names: Ketotriclabendazole. Grades: Highly Purified. CAS No. 1201920-88-8. Pack Sizes: 10mg. Molecular Formula: C??H?Cl?N?O?, Molecular Weight: 329.57. US Biological Life Sciences. | Worldwide |
| 5-Chloro-6-fluoro-1,3-dihydro-2H-benzimidazol-2-one | Heterocyclic Organic Compound. Alternative Names: 5-Chloro-6-fluoro-1,3-dihydro-2H-benzimidazol-2-one. CAS No. 1075753-25-1. Molecular formula: C7H4ClFN2O. Mole weight: 186.571. Purity: 0.96. IUPACName: 5-chloro-6-fluoro-1,3-dihydrobenzimidazol-2-one. Canonical SMILES: C1=C2C(=CC(=C1F)Cl)NC(=O)N2. Catalog: ACM1075753251. | |
| 5-Isopropyl-1,3-dihydro-benzimidazol-2-one | Heterocyclic Organic Compound. Alternative Names: 5-ISOPROPYL-1,3-DIHYDRO-BENZIMIDAZOL-2-ONE;2-Benzimidazolinone,5-isopropyl-(6CI). CAS No. 103151-03-7. Molecular formula: C10H12N2O. Mole weight: 176.22. Catalog: ACM103151037. | |
| Akti-1/2 (1,3-Dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-g]guinoxalin-7-yl)phenyl]methyl]4-piperidinyl]-2H-benzimidazol-2-one) | Allosteric Akt (PKB) inhibitors used in synergistic combination therapy for the treatment of cancer. Group: Biochemicals. Alternative Names: 1,3-Dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-g]guinoxalin-7-yl)phenyl]methyl]4-piperidinyl]-2H-benzimidazol-2-one. Grades: Highly Purified. CAS No. 612847-09-3. Pack Sizes: 2mg. US Biological Life Sciences. | Worldwide |
| Akt Inhibitor, Isozyme-selective (1,3-Dihydro-1-(1-((4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)phenyl)methyl)-4-piperidinyl)-2H-benzimidazol-2-one; Akti-1/2) | Cell-permeable. A potent and selective inhibitor of Akt1/Akt2 activity (IC?? = 58nM (Akt1), 210nM (Akt2) and 2.12uM (Akt3) in in vitro kinase assays). The inhibition appears to be pleckstrin homology (PH) domain-dependent. It does not exhibit any inhibitory effect against PH domain-lacking Akts, or other closely related AGC family kinases, PKA, PKC, and SGK, even at concentrations (50uM). Group: Biochemicals. Grades: Highly Purified. CAS No. 612847-09-3. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2 (1,3-Dihydro-1-(1-((4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)phenyl)methyl)-4-piperidinyl)-2H-benzimidazol-2-one, Akti-1/2) | A cell-permeable, reversible, potent, and selective inhibitor of Akt1/Akt2 activity (IC50=58nM, 210nM, and 2.12uM for Akt1, Akt2, and Akt3, respectively, in in vitro kinase assays). The inhibition is reported to be pleckstrin homology (PH) domain-dependent. It does not exhibit any inhibitory effect against PH domain-lacking Akts, or other closely related AGC family kinases, PKA, PKC, and SGK, even at concentrations as high as 50uM. Overcomes Akt1/Akt2-mediated resistance to chemotherapeutics in tumor cells and is shown to block basal and stimulated phosphorylation / activation of Akt1/Akt2 both in cultured cells in vitro and in mice in vivo. Group: Biochemicals. Grades: Highly Purified. CAS No. 612847-09-3. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
| Oxatomide (1-[3-[4-(Diphenylmethyl)-1-piperazinyl]propyl]-1,3-dihydro-2H-benzimidazol-2-one,. R-35443, Celtect, Cobiona, Dasten, Tinset) | Orally active anti-allergic agent; related structurally to cinnarizine and having a novel biphasic mode of action. Group: Biochemicals. Alternative Names: 1-[3-[4-(Diphenylmethyl)-1-piperazinyl]propyl]-1,3-dihydro-2H-benzimidazol-2-one;R-35443; Celtect; Cobiona; Dasten; Tinset. Grades: Highly Purified. CAS No. 60607-34-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 1-(1-(3-(p-Fluorobenzoyl)propyl)-1,2,3,6-tetrahydro-4-pyridyl)-2-benzimidazolinone | 1-(1-(3-(p-Fluorobenzoyl)propyl)-1,2,3,6-tetrahydro-4-pyridyl)-2-benzimidazolinone. Group: Biochemicals. Alternative Names: 1-[1-[4-(4-Fluorophenyl)-4-oxobutyl]-1,2,3,6-tetrahydro-4-pyridinyl]-1,3-dihydro-2H-benzimidazol-2-one; Dehydrobenzperidol; Dridol. Grades: Highly Purified. CAS No. 548-73-2. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C22H22FN3O2. US Biological Life Sciences. | Worldwide |
| 1-(2-Ethoxy-ethyl)-1,3-dihydro-benzoimidazol-2-one | Heterocyclic Organic Compound. Alternative Names: 1-(2-ETHOXY-ETHYL)-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE;1-(2-ethoxyethyl)-1H-benzo[d]imidazol-2(3H)-one;1-(2-Ethoxyethyl)-1,3-dihydro-2H-benzimidazol-2-one. CAS No. 101953-61-1. Molecular formula: C11H14N2O2. Mole weight: 206.24. Density: 1.151. Catalog: ACM101953611. | |
| 1,4-Dihydro-1-(5-methoxy-1H-benzimidazol-2-yl)-2,3,5-trimethyl-4-oxopyridine | 1,4-Dihydro-1-(5-methoxy-1H-benzimidazol-2-yl)-2,3,5-trimethyl-4-oxopyridine is used as a solvent in paint and a precursor to vitamin E. Synonyms: 1-(5-methoxy-1H-benzimidazol-2-yl)-2,3,5-trimethylpyridin-4-one; 1-(5-Methoxy-1H-benzimidazol-2-yl)-2,3,5-trimethyl-4(1H)-pyridinone; 4(1H)-Pyridinone, 1-(5-methoxy-1H-benzimidazol-2-yl)-2,3,5-trimethyl-. Molecular formula: C16H17N3O2. Mole weight: 283.32. |  |
| 5,6-Diamino-2-hydroxybenzimidazole dihydrochloride | 5,6-Diamino-2-hydroxybenzimidazole dihydrochloride. Group: Biochemicals. Alternative Names: 5,6-Diamino-1,3-dihydro-2H-benzimidazol-2-one dihydrochloride; 5,6-Diamino-2(3H)-benzimidazolone dihydrochloride; 5,6-Diaminobenzimidazolone dihydrochloride. Grades: Highly Purified. CAS No. 42815-81-6. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C7H10Cl2N4O. US Biological Life Sciences. | Worldwide |
| 5-Chloro-1-(4-piperidinyl)-2-benzimidazolidinone | 5-Chloro-1-(4-piperidinyl)-2-benzimidazolidinone. Group: Biochemicals. Alternative Names: Des[3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl] domperidone; 4-(6-Chloro-1,2-dihydro-2-oxobenzo[d]imidazol-3-yl)piperidine; 5-Chloro-1-(4-piperidinyl)-1,3-dihydro-2H-benzimidazol-2-one. Grades: Highly Purified. CAS No. 53786-28-0. Pack Sizes: 2g, 5g, 10g, 25g, 50g. Molecular Formula: C12H14ClN3O. US Biological Life Sciences. | Worldwide |
| 5-(difluoromethoxy)-1H-benzo[d]imidazol-2-ol | An impurity of Pantoprazole which is a proton pump inhibitor used to treat erosive esophagitis (damage to the esophagus from stomach acid), and other conditions involving excess stomach acid such as Zollinger-Ellison syndrome. Synonyms: 2H-Benzimidazol-2-one, 5-(difluoromethoxy)-1,3-dihydro-; Pantoprazole impurity 19. CAS No. 1806469-15-7. Molecular formula: C8H6F2N2O2. Mole weight: 200.14. | |
| Akti-1/2 | Akti-1/2. Group: Biochemicals. Alternative Names: 1,3-Dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)phenyl]methyl]4-piperidinyl]-2H-benzimidazol-2-one. Grades: Highly Purified. CAS No. 612847-09-3. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C34H29N7O. US Biological Life Sciences. | Worldwide |
| AKT inhibitor VIII | Akt Inhibitor VIII is a cell-permeable quinoxaline compound that has been shown to potently, selectively, allosterically, and reversibly inhibit Akt1, Akt2, and Akt3 activity. It does not exhibit any inhibitory effect against pleckstrin homology (PH) domain-lacking Akts, AGC family kinases, PKA, PKC or SGK. It also prevails over Akt1/Akt2-mediated resistance to chemotherapeutics in tumor cells and has been shown to block basal and stimulated phosphorylation/activation of Akt1/Akt2 in cultured cells and in mice. Synonyms: AKT inhibitor VIII; AKT-inhibitor-VIII; AKT inhibitor-8; AKT-inhibitor-8; Akt-I 1,2; Akti-1/2. Sigma-A6730. 2H-Benzimidazol-2-one, 1,3-dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)phenyl]methyl]-4-piperidinyl]-. Grades: >98%. CAS No. 612847-09-3. Molecular formula: C34H29N7O. Mole weight: 551.64. | |
| Azilsartan Impurity I | Azilsartan Impurity I is an impurity found in azilsartan, a medication primarily used for the therapy of hypertension. Synonyms: Methyl 1-((2'-cyanobiphenyl-4-yl) Methyl)-2H-benziMidazol-2-one-7-carboxylate); Methyl 3-((2'-cyanobiphenyl-4-yl)Methyl)-2-oxo-2,3-dihydro-1H-benzo[d]iMidazole-4-carboxylate. Grades: > 95%. CAS No. 139481-33-7. Molecular formula: C23H17N3O3. Mole weight: 383.41. | |
| Benperidol EP Impurity B | Benperidol EP Impurity B. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1-[1-[4-(2-fluorophenyl)-4-oxobutyl]piperidin-4-yl]-1,3-dihydro-2H-benzimidazol-2-one. Molecular Formula: C22H24FN3O2. Mole Weight: 381.44. Catalog: APB03850. | |
| Benperidol EP Impurity C | Benperidol EP Impurity C. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1-[1-[4-oxo-4-[4-[4-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)piperidin-1-yl]phenyl]butyl]piperidin-4-yl]-1,3-dihydro-2H-benzimidazol-2-one. Molecular Formula: C34H38N6O3. Mole Weight: 578.70. Catalog: APB03849. | |
| Benperidol EP Impurity D | Benperidol EP Impurity D. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: cis-1-[1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl 1-oxide]-1,3-dihydro-2H-benzimidazol-2-one. Molecular Formula: C22H24FN3O3. Mole Weight: 397.44. Catalog: APB03847. | |
| Benperidol EP Impurity E | Benperidol EP Impurity E. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: trans-1-[1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl 1-oxide]-1,3-dihydro-2H-benzimidazol-2-one. Molecular Formula: C22H24FN3O3. Mole Weight: 397.44. Catalog: APB03848. | |
| BGB-283 | BGB-283 is a selective Epidermal growth factor receptor and Proto oncogene protein b raf inhibitor under the development of BeiGene. BGB-283 shows antitumor activity in B-RAF Mutated Colorectal Cancers. In vitro, BGB-283 can inhibit B-RAFV600E-activated ERK phosphorylation and cell proliferation. In vivo, BGB-283 can lead to dose-dependent tumor growth inhibition accompanied by partial and complete tumor regressions in both cell-line derived and primary human colorectal tumor xenografts bearing B-RAFV600E mutation. Phase I clinical trials for the treatment of solid tumours are on-going. Uses: Solid tumours. Synonyms: UNII-8762XZS5ZF; 8762XZS5ZF; BGB-283; BGB 283; BGB283; Beigene-283; Beigene283; Beigene 283; Lifirafenib; Compound 2.2b; Beigene-283; GTPL8958;5-[[(1R,1aS,6bR)-1-[6-(trifluoromethyl)-1H-benzimidazol-2-yl]-1a,6b-dihydro-1H-cyclopropa[b][1]benzofuran-5-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one. Grades: 98%. CAS No. 1446090-77-2. Molecular formula: C25H17F3N4O3. Mole weight: 478.31. | |
| BMS 433771 | BMS 433771 is a potent inhibitor of RSV replication in vitro with an average EC of 20nM. Uses: Viral fusion protein inhibitor. Synonyms: BMS 433771; BMS433771; BMS-433771; BMS-433771 HCl hydrate; BMS-433771 HCl; BMS-433771 hydrochloride. 1-cyclopropyl-1,3-dihydro-3-((1-(3-hydroxypropyl)-1H-benzimidazol-2-yl)methyl)-2H-Imidazo(4,5-c)pyridin-2-one. Grades: ≥98%. CAS No. 380603-10-1. Molecular formula: C20H21N5O2. Mole weight: 363.41. | |
| BMS695735 | BMS695735 is a benzimidazole inhibitor of the insulin-like growth factor-1 receptor. It was also found to have potent CYP3A4 inhibition. It has broad spectrum in vivo antitumor activity. Uses: Bms695735 has broad spectrum antitumor activity. Synonyms: BMS-695735; BMS 695735; BMS695735; CHEMBL459729; BDBM27888; DNC008930; 2(1H)-Pyridinone, 4-((2-(4-chloro-1H-pyrazol-1-yl)ethyl)amino)-3-(5-(1-(3-fluoropropyl)-4-piperidinyl)-7-methyl-1H-benzimidazol-2-yl)-;(3Z)-4-[2-(4-chloropyrazol-1-yl)ethylamino]-3-[6-[1-(3-fluoropropyl)piperidin-4-yl]-4-methyl-1,3-dihydrobenzimidazol-2-ylidene]pyridin-2-one. Grades: 95%. CAS No. 1054315-48-8. Molecular formula: C26H31ClFN7O. Mole weight: 512.02. | |
| CGP 12177 | CGP 12177 is a partial β3-adrenoceptor agonist with Ki value of 88 nM. It is also an of β1- and β2-adrenoceptors antagonist with Ki values of 0.9 nM and 4 nM for β1-, β2adrenoceptors. CGP12177 can slightly activate L-type Ca2+ current in human ventricular myocytes. Uses: Adrenergic beta-antagonists. Synonyms: CGP 12177; CGP12177; CGP-12177; Tbhpbo; CGP 12177 Hydrochloride; CGP 12177 HCl. 4-[3-[(1,1-Dimethylethyl)amino]2-hydroxypropoxy]-1,3-dihydro-2H-benzimidazol-2-one;64208-32-8(hydrochloride). Grades: 98%. CAS No. 81047-99-6. Molecular formula: C14H21N3O3. Mole weight: 279.34. | |
| CGP 12177 hydrochloride | CGP 12177 hydrochloride is a partial agonist of β3-adrenoceptors, and also an antagonist of β1- and β2-adrenoceptors (Ki = 0.9, 4 and 88 nM for β1, β2 and β3 receptors respectively). Synonyms: CGP 12177 hydrochloride; CGP12177 hydrochloride; CGP-12177 hydrochloride; 4-[3-[(1,1-Dimethylethyl)amino]2-hydroxypropoxy]-1,3-dihydro-2H-benzimidazol-2-one hydrochloride. CAS No. 64208-32-8. Molecular formula: C14H21N3O3.HCl. Mole weight: 315.8. | |
| CGS 9343B | CGS 9343B is a calmodulin (CaM) antagonist that inhibits calmodulin-stimulated cAMP phosphodiesterase activity (IC50 = 3.3 nM). It also prevents estrogen-induced transcription activation by ER, reversibly blocks voltage-activated Na+, Ca2+ and K+ currents in PC12 cells and inhibits nAChR. Synonyms: CGS 9343B; CGS9343B; CGS-9343B; Zaldaride Maleate; 1,3-Dihydro-1-[1-[(4-methyl-4H,6H-pyrrolo[1,2-a][4,1]benzoxazepin-4-yl)methyl]-4-piperidinyl]-2H-benzimidazol-2-one maleate. Grades: ≥98% by HPLC. CAS No. 109826-27-9. Molecular formula: C26H28N4O2.C4H4O4. Mole weight: 544.61. | |
| D-3263 | D-3263 is a TRPM8 agonist ( transient receptor potential melastatin member 8) with potential antineoplastic activity. The active ingredient in enteric-coated TRPM8 agonist D-3263 hydrochloride binds to and activates TRPM8, which may result in an increase in calcium and sodium entry; the disruption of calcium and sodium homeostasis; and the induction of cell death in TRPM8-expressing tumor cells. This agent may decrease dihydrotestosterone (DHT) levels, which may contribute to its inhibitory effects on prostate cancer and BPH. TRPM8 is a transmembrane calcium channel protein that is normally expressed in prostate cells and appears to be overexpressed in benign prostatic hyperplasia (BPH) and in prostate cancer. Synonyms: 3-(2-Aminoethyl)-1-((1R,2S,5R)-2-isopropyl-5-methylcyclohexanecarbonyl)-5-methoxy-1H-benzo[d]imidazol-2(3H)-one; 2H-Benzimidazol-2-one, 3-(2-aminoethyl)-1,3-dihydro-5-methoxy-1-(((1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl)carbonyl)-; 3-(2-Aminoethyl)-1-{[(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl]carbonyl}-5-methoxy-1,3-dihydro-2H-benzimidazol-2-one. Grades: ≥95%. CAS No. 947257-66-1. Molecular formula: C21H31N3O3. Mole weight: 373.49. | |
| DCEBIO | DCEBIO is a Ca2+ sensitive K+ channel (SKCa) agonist stimulating Cl- secretion via activation of hKCa3.1 (IK1) potassium channels and activation of an apical Cl- conductance. Synonyms: 5,6-Dichloro-1-ethyl-1,3-dihydro-2H-benzimidazol-2-one; Dichloro-EBIO. Grades: ≥99% by HPLC. CAS No. 60563-36-2. Molecular formula: C9H8Cl2N2O. Mole weight: 231.08. | |
| Domperidone | A novel peripheral dopamine receptor antagonist that does not cross the blood-brain barrier; anti-emetic. Group: Biochemicals. Alternative Names: 5-Chloro-1-[1-[3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one. Grades: Highly Purified. CAS No. 57808-66-9. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| Domperidone Impurity | 1-(3-Chloropropyl)-1,3-dihydrobenzimidazol-2-one is a benzimidazole derivative used in the preparation of neuroleptic and antiallergic agents. Synonyms: 1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one. Grades: > 95%. CAS No. 62780-89-6. Molecular formula: C10H11ClN2O. Mole weight: 210.66. | |
| Domperidone Impurity A | A metabolite of the gastrokinetic and antinauseant drug Domperidone. Synonyms: 5-Chloro-1-(4-piperidinyl)-2-benzimidazolidinone; Des[3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl] Domperidone; 4-(6-Chloro-1,2-dihydro-2-oxobenzo[d]imidazol-3-yl)piperidine; 5-Chloro-1-(4-piperidinyl)-1,3-dihydro-2H-benzimidazol-2-one; 5-Chloro-1-(p. Grades: > 95%. CAS No. 53786-28-0. Molecular formula: C12H14ClN3O. Mole weight: 251.71. | |
| Domperidone Impurity B | An impurity of the gastrokinetic and antinauseant drug Domperidone. Synonyms: 4-(6-Chloro-1,2-dihydro-2-oxobenzo[d]imidazol-3-yl)piperidine-1-carbaldehyde; 5-Chloro-1-(4-formylpiperidinyl)-1,3-dihydro-2H-benzimidazol-2-one; 5-Chloro-1-(4-formylpiperidinyl)-1H-benzimidazol-2(3H)-one. Grades: > 95%. CAS No. 1346598-11-5. Molecular formula: C13H14ClN3O2. Mole weight: 279.72. | |
| Domperidone Impurity C | An oxygenated metabolite of the gastrokinetic and antinauseant drug Domperidone. Synonyms: 5-Chloro-1-[1-[3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]-1-oxido-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one; Domperidine Impurity C; 5-Chloro-1-[1-[3-[(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]-4-piperidinyl]]-1,3-dihydro-2H-benzimidazo. Grades: > 95%. CAS No. 118435-03-3. Molecular formula: C22H24ClN5O3. Mole weight: 441.91. | |
| Domperidone Impurity D | An impurity of the gastrokinetic and antinauseant drug Domperidone. Synonyms: 5-Chloro-3-[3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]-1-[1-[3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one. Grades: > 95%. CAS No. 1614255-34-3. Molecular formula: C32H34ClN7O3. Mole weight: 600.11. | |
| Domperidone Impurity E | An impurity of the gastrokinetic and antinauseant drug Domperidone. Synonyms: 3'-[3-(2,3-Dihydro-2-oxo-1H-benzimidazol-1-yl)propyl] Domperidone; 5-Chloro-1-[1-[3-[2,3-dihydro-2-oxo-3-[3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]-1H-benzimidazol-1-yl]propyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one. Grades: > 95%. CAS No. 1346602-50-3. Molecular formula: C32H34ClN7O3. Mole weight: 600.13. | |
| Droperidol | A D1, D2 dopamine receptor antagonist; butyrophenone antipsychotic and anti-emetic. Group: Biochemicals. Alternative Names: 1-[1-[4-(4-Fluorophenyl)-4-oxobutyl]-1,2,3,6-tetrahydro-4-pyridinyl]-1,3-dihydro-2H-benzimidazol-2-one; Dehydrobenzperidol; Dridol; Droleptan; Inapsin; Inapsine; Inopsin; McN-JR 4749; NSC 169874; Neurolidol; R 474; Sintodril. Grades: Highly Purified. CAS No. 548-73-2. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Droperidol Impurity E | An impurity of Droperidol. Synonyms: 1-[1-[4-[4-[4-(2-Oxo-2,3-dihydro-1H-benzimidazol-1-yl)-3,6-dihydropyridin-1(2H)-yl]-1-oxobutyl]phenyl]-1,2,3,6-tetrahydro-4-pyridinyl]-1,3-dihydro-2H-benzimidazol-2-one. Grades: > 95%. CAS No. 1346604-17-8. Molecular formula: C34H34N6O3. Mole weight: 574.67. | |
| Emedastine EP Impurity A | Emedastine EP Impurity A. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1-(2-Ethoxyethyl)-1,3-dihydro-2H-benzimidazol-2-one. CAS No. 101953-61-1. Molecular Formula: C11H14N2O2. Mole Weight: 206.11. Catalog: APB101953611. | |
| GSK 1702934A | GSK 1702934A is a potent and selective TRPC3/6 activator (EC50 = 80 and 440 nM for TRPC3 and 6, respectively). However, it exhibits no activity at TRPV4, TRPA1, M1, M4, CaV1.2, hERG, NaV1.5, or CXCR5 receptors at concentrations <10 μM. Synonyms: 1,3-Dihydro-1-[1-[(5,6,7,8-tetrahydro-4H-cyclohepta[b]thien-2-yl)carbonyl]-4-piperidinyl]-2H-benzimidazol-2-one; 3-[1-(5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-2-carbonyl)piperidin-4-yl]-1H-benzimidazol-2-one; GSK-2934A. Grades: ≥98% by HPLC. CAS No. 924377-85-5. Molecular formula: C22H25N3O2S. Mole weight: 395.52. | |
| Hydroxocobalamin Chloride | One of the analog of Vitamin B12, which has been found to be related to the metabolism of cells in human body, especially DNA synthesis, amino acid as well as fatty acid metabolism. Synonyms: Co-Hydroxy-cobinamide-f-(dihydrogen phosphate) 3'-Ester with (5,6-Dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole-κN3) Inner Salt Hydrochloride; Dihydroxide-cobinamide Dihydrogen Phosphate (Ester) 3'-Ester with 5,6-Dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole Hydrochloride Mono(inner salt). CAS No. 58288-50-9. Molecular formula: C62H89CoN13O15P. HCl. Mole weight: 1346.36. | |
| (±)-J 113397 | (+/-)-J 113397 has been found to be a NOP receptor antagonist and could restrain nociceptin/orphanin FQ-induced hyperalgesia in the mouse tail-flick test. Synonyms: (±)-J 113397; (±)-J113397; (±)-J-113397; (±)-1-[(3R*,4R*)-1-(Cyclooctylmethyl)-3-(hydroxymethyl)-4-piperidinyl]-3-ethyl-1,3-dihydro-2H-benzimidazol-2-one. Grades: ≥98% by HPLC. CAS No. 217461-40-0. Molecular formula: C24H37N3O2. Mole weight: 399.57. | |
| JNJ 55511118 | JNJ 55511118 has been found to be an AMPA receptor modulator and could probably be used as an anticonvulsant. Synonyms: JNJ-55511118; JNJ 55511118; JNJ55511118; 5-[2-Chloro-6-(trifluoromethoxy)phenyl]-1,3-dihydro-2H-benzimidazol-2-one. Grades: ≥98% by HPLC. CAS No. 2036081-86-2. Molecular formula: C14H8ClF3N2O2. Mole weight: 328.67. | |
| Lansoprazole EP Impurity D | 2-Hydroxybenzimidazole is an intermediate of Droperidol and Lansoprazole. Synonyms: 2H-Benzimidazol-2-one, 1,3-dihydro-; 1,3-Dihydro-2H-benzimidazol-2-one; 2-Benzimidazolinone; 1,3-Dihydro-2H-benzimidazole-2-one; 1,3-Dihydro-2H-benzo[d]imidazol-2-one; 1H-1,3-Benzodiazol-2-ol; 1H-Benzimidazol-2(3H)-one; 1H-Benzo[d]imidazol-2(3H)-one; 1H-Benzoimidazol-2-ol; 2(3H)-Benzimidazolone; 2(3H)-Oxobenzimidazole; 2,3-Dihydro-1H-1,3-benzodiazol-2-one; 2,3-Dihydro-2-oxo-1H-benzimidazole; 2-Benzimidazolol; 2-Benzimidazolone; 2-Hydroxybenzimidazole; N,N'-(1,2-Phenyleneurea); NSC 10383; NSC 178108; o-Phenyleneurea; Urea, N,N'-(1,2-phenylene)-. Grades: ≥95%. CAS No. 615-16-7. Molecular formula: C7H6N2O. Mole weight: 134.14. | |
| Mebendazole Impurity B | 5-Benzoyl-1,3-dihydro-2H-benzimidazol-2-one contains a benzimidazolone moiety which has been seen to inhibit p38 MAP kinase , a crucial protein in the activation of biological factors related to psoriasis, rheumatoid arthritis and other inflammatory disea. Synonyms: 5-Benzoyl-1,3-dihydro-2H-benzimidazol-2-one; 5-Benzoyl-2-benzimidazolinone. Grades: > 95%. CAS No. 21472-33-3. Molecular formula: C14H10N2O2. Mole weight: 238.24. | |
| Milenperone | Milenperone. Group: Biochemicals. Alternative Names: 5-Chloro-1-[3-[4-(4-fluorobenzoyl)-1-piperidinyl]propyl]-1,3-dihydro-2H-benzimidazol-2-one; R 34009. Grades: Highly Purified. CAS No. 59831-64-0. Pack Sizes: 50mg, 100mg. Molecular Formula: C22H23ClFN3O2. US Biological Life Sciences. | Worldwide |
| Nitritocobalamin | One of the analog of Vitamin B12, which has been found to be related to the metabolism of cells in human body, especially DNA synthesis, amino acid as well as fatty acid metabolism. Synonyms: Co-(nitrito-κO)-cobinamide Dihydrogen Phosphate (Ester) Inner Salt 3'-Ester with (5,6-Dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole-κN3); Nitrocobalamin; Vitamin B12c; Cobinamide, hydroxide nitrite (salt), dihydrogen phosphate (ester), inner salt, 3'-ester with 5,6-dimethyl-1-α-D-ribofuranosylbenzimidazole; Cobinamide, nitrite (salt), dihydrogen phosphate (ester), inner salt, 3'-ester with 5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole. CAS No. 20623-13-6. Molecular formula: C62H88CoN13O14P NO2. Mole weight: 1375.35. | |
| Oxatomide | ≥99%. Uses: For analytical and research use. Group: Fluorescence/luminescence spectroscopy; api standards; pharmaceutical toxicology. Alternative Names: R 35443, KW 4354, Celtect, NSC 309710,2H-Benzimidazol-2-one, 1-[3-[4-(diphenylmethyl)-1-piperazinyl]propyl]-1,3-dihydro-, Tinset, Dasten, Cobiona, Oxatomide. CAS No. 60607-34-3. Pack Sizes: 10MG. IUPAC Name: 3-[3-(4-benzhydrylpiperazin-1-yl)propyl]-1H-benzimidazol-2-one. Molecular Formula: C27H30N4O. Mole Weight: 426.55. EC Number: 262-320-9. Catalog: APS60607343. Assay: ≥99%. SMILES: O=C1Nc2ccccc2N1CCCN3CCN (CC3)C (c4ccccc4)c5ccccc5. Format: Neat. Shipping: Room Temperature. | |
| Oxatomide | Oxatomide. Group: Biochemicals. Alternative Names: 1-[3-[4-(Diphenylmethyl)-1-piperazinyl]propyl]-1,3-dihydro-2H-benzimidazol-2-one; R-35443; Celtect. Grades: Highly Purified. CAS No. 60607-34-3. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C27H30N4O. US Biological Life Sciences. | Worldwide |
| PF 05175157 | PF-05175157 is a selective inhibitor of both acetyl-CoA carboxylase isoform ACC1 and isoform ACC2 dominant. IC50 values are 27 nM and 33 nM, respectively. It was originated by Pfizer. ACC inihibitors can inhibit de novo lipogenesis and increase β-oxidation of long-chain fatty acids. In Feb 2015, Phase-II for Type-2 diabetes mellitus in USA was discontinued. Uses: Type 2 diabetes mellitus. Synonyms: PF-05175157; PF05175157; 1,4-Dihydro-1'-[(2-methyl-1H-benzimidazol-6-yl)carbonyl]-1-(1-methylethyl)-spiro[5H-indazole-5,4'-piperidin]-7(6H)-one. Grades: 98%. CAS No. 1301214-47-0. Molecular formula: C23H27N5O2. Mole weight: 405.50. | |
| Pimozide Impurity E | An impurity of Pimozide (Orap) which is an antipsychotic drug of the diphenylbutylpiperidine class. Synonyms: Pimozide N-Oxide; 1083078-88-9; UNII-KC2BVV76IU; KC2BVV76IU; Pimozide specified impurity E [EP]; 1-(1-(4,4-Bis(4-fluorophenyl)butyl)piperidin-4-yl 1-oxide)-1,3-dihydro-2H-benzimidazol-2-one; 2H-Benzimidazol-2-one, 1-(1-(4,4-bis(4-fluorophenyl)butyl)-1-oxido-4-piperidinyl)-1,3-dihydro-; 3-[1-[4,4-bis(4-fluorophenyl)butyl]-1-oxidopiperidin-1-ium-4-yl]-1H-benzimidazol-2-one; Pimozide impurity E; SCHEMBL1152903; DTXSID00148496; BCP15238; PIMOZIDE IMPURITY E [EP IMPURITY]; FT-0673904; F97131; Q27282170; 210690-27-0; CIS-(1S,4R)-1-[4,4-BIS(4-FLUOROPHENYL)BUTYL]-4-(2-OXO-2,3-DIHYDRO-1H-1,3-BENZODIAZOL-1-YL)PIPERIDIN-1-IUM-1-OLATE. Grades: > 95%. Molecular formula: C28H29F2N3O2. Mole weight: 477.56. | |
| Pimozide N-Oxide | Pimozide N-Oxide is an impurity of Pimozide with hERG inhibitory activity. Pimozide impurity E. Group: Biochemicals. Alternative Names: 1-[1-[4,4-Bis(4-fluorophenyl)butyl]-1-oxido-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one. Grades: Highly Purified. CAS No. 1083078-88-9. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| SI-2 | SI-2 is an inhibitor of steroid receptor coactivator 3 (SRC-3). It induces death in various breast cancer cells with IC50 values of 3-20 nM without affecting normal cell viability. Synonyms: Ethanone, 1-(2-pyridinyl)-, 2-(1-methyl-1H-benzimidazol-2-yl)hydrazone, (1E)-; (1E)-1-(2-Pyridinyl)ethanone 2-(1-methyl-1H-benzimidazol-2-yl)hydrazone; 2H-Benzimidazol-2-one, 1,3-dihydro-1-methyl-, [(2E)-1-(2-pyridinyl)ethylidene]hydrazone; EPH 116; (E)-SI-2. Grades: ≥98%. CAS No. 380537-35-9. Molecular formula: C15H15N5. Mole weight: 265.31. | |
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