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Benzofuran-2-carboxylicacid ethyl ester. Group: Biochemicals. Grades: Highly Purified. CAS No. 3199-61-9. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C11H10O3. US Biological Life Sciences.
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Benzofuran-6-carboxylicAcid
Benzofuran-6-carboxylicAcid is a reagent in the development of potent LFA-1/ICAM antagonist SAR 118 as an opthalmic solution for treating dry eyes. Preparation of piperidinylpyrimidine derivatives as inhibitors of HIV-1 LTR activation. Group: Biochemicals. Grades: Highly Purified. CAS No. 77095-51-3. Pack Sizes: 250mg, 1g. Molecular Formula: C9H6O3, Molecular Weight: 162.139999999999. US Biological Life Sciences.
2-(tert-Butoxycarbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylicAcid is a reagent in the preparation of N-benzofuranylcarbonyl dichlorotetra hydroisoquinolinyl carbonyl methyl sulfonyl L-phenylalanine as LFA-1 inhibitor and polymorph thereof for the treatment of LFA -1 mediated diseases. Group: Biochemicals. Grades: Highly Purified. CAS No. 851784-82-2. Pack Sizes: 250mg, 1g. Molecular Formula: C15H17Cl2NO4, Molecular Weight: 346.21. US Biological Life Sciences.
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3,5-Dihydroxynapthalene-2-carboxylicAcid
3,5-Dihydroxynapthalene-2-carboxylicAcid is used as a negative or positive NMDA receptor inhibitor, via allosteric control. NMDA receptors regulate CHN (central nervous system) functions. Also used as a protein tyrosine phosphatase inhibitor due to the benzofuran-like moiety in the substructure. Group: Biochemicals. Alternative Names: UBP551. Grades: Highly Purified. CAS No. 89-35-0. Pack Sizes: 1g, 10g, 50g. Molecular Formula: C11H8O4, Molecular Weight: 204.18. US Biological Life Sciences.
6-Carboxyfluorescein diacetate succinimidyl ester is an amine-reactive probe for labeling human intervertebral disk cells in vitro by fluorescence microscopy. It is also used for determining intracellular pH in bacteria by fluorometry. Synonyms: 6-CFDA N-succinimidyl ester; 6-CFDA SE; 6-Carboxy-fluorescein diacetate N-succinimidyl ester; (2,5-dioxopyrrolidin-1-yl) 3',6'-diacetyloxy-1-oxospiro[2-benzofuran-3,9'-xanthene]-5-carboxylate; 6-Carboxy-di-O-acetylfluorescein N-succinimidyl ester; Spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-6-carboxylicacid, 3',6'-bis(acetyloxy)-3-oxo-, 2,5-dioxo-1-pyrrolidinyl ester; 2,5-Dioxo-1-pyrrolidinyl 3',6'-bis(acetyloxy)-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-6-carboxylate; 2,5-Pyrrolidinedione, 1-[[[3',6'-bis(acetyloxy)-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-6-yl]carbonyl]oxy]-. Grades: ≥95%. CAS No. 150206-15-8. Molecular formula: C29H19NO11. Mole weight: 557.46.
Heterocyclic Organic Compound. Alternative Names: 6-tert-Butyl-2,3-dihydro-benzo[1,4]dioxine-2-carboxylicacid;6-Methoxy-3-methyl-benzofuran-2-carboxylicacid. CAS No. 10410-29-4. Molecular formula: C11H10O4. Mole weight: 206.19. Catalog: ACM10410294.
Ethyl 5-amino-1-benzofuran-2-carboxylate
Ethyl 5-amino-1-benzofuran-2-carboxylate is used as an synthetic intermediate in the preparation of indolebutyl piperazines, a class of dual 5-HT1A receptor agonists and serotonin reuptake inhibitors. Ethyl 5-amino-1-benzofuran-2-carboxylate was also used as a potential radiolabelled analog for melanoma imaging and targeted radiotherapy. Group: Biochemicals. Alternative Names: 5-Aminobenzofuran-2-carboxylicacid ethyl ester; Ethyl 5-aminobenzofuran-2-carboxylate. Grades: Highly Purified. CAS No. 174775-48-5. Pack Sizes: 1g. US Biological Life Sciences.
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Geodin
An antibiotic produced by the strain of Aspergillus terreus, Geodin is resistant to gram-positive bacteria, negative bacteria (weak) and plant viruses. Synonyms: (+)-Estin; 5,7-dichloro-4-hydroxy-5'-methoxy-6-methyl-3,3'-dioxo-1'-spiro[benzofuran-2,6'-cyclohexa-1,4-diene]carboxylicacid methyl ester; (1'R)-5,7-dichloro-4-hydroxy-6'-methoxy-6-methyl-3,4'-dioxo-spiro[benzofuran-2(3H),1'-[2,5]cyclohexadiene]-2'-carboxylicacid, methyl ester. Grades: ≥95%. CAS No. 427-63-4. Molecular formula: C17H12Cl2O7. Mole weight: 399.18.
Geodin
Plasminogen activator inhibitor (PAI-1). Glucose uptake stimulator. Group: Biochemicals. Alternative Names: (1'R)-5,7-dichloro-4-hydroxy-6'-methoxy-6-methyl-3,4'-dioxo-spiro[benzofuran-2(3H),1'-[2,5]cyclohexadiene]-2'-carboxylicacid, methyl ester, Erdin (+)-form methyl ester; Estin. Grades: Highly Purified. CAS No. 427-63-4. Pack Sizes: 1mg, 5mg. Molecular Formula: C??H??Cl?O?. US Biological Life Sciences.
Worldwide
Ivacaftor CarboxylicAcid Lactone
Ivacaftor CarboxylicAcid Lactone is related to Ivacaftor, which is a CFTR potentiator used in the treatment of cystic fibrosis. Synonyms: N-[5-(1,1-Dimethylethyl)-2,3-dihydro-3,3-dimethyl-2-oxo-6-benzofuranyl]-1,4-dihydro-4-oxo-3-quinolinecarboxamide; N-(5-(tert-Butyl)-3,3-dimethyl-2-oxo-2,3-dihydrobenzofuran-6-yl)-4-oxo-1,4-dihydroquinoline-3-carboxamide. Grades: ≥95%. CAS No. 1246213-41-1. Molecular formula: C24H24N2O4. Mole weight: 404.46.
Lithospermic acid
Lithospermic acid is extracted from the roots of Lithospermum ruderale. It is Cardiotonic agent. It possesses anti-HIV activity. Synonyms: 4-{(E)-2-[1-Carboxy-2-(3,4-dihydroxy-phenyl)-ethoxycarbonyl]-vinyl}-2-(3,4-dihydroxy-phenyl)-7-hydroxy-2,3-dihydro-benzofuran-3-carboxylicacid; Aids071478; Aids-071478; Clinopodic acid H. Grades: >98%. CAS No. 28831-65-4. Molecular formula: C27H22O12. Mole weight: 538.5.
Fmoc-Arg(Me,pbf)-OH can be used as a reactant/reagent in design, synthesis and structure-activity relationship of macrocyclic peptidomimetics that bind to WDR5 and block WDR5-MLL protein-protein interaction. Synonyms: Fmoc-L-Arg(Me,Pbf)-OH; N5-[[[ (2, 3-Dihydro-2, 2, 4, 6, 7-pentamethyl-5-benzofuranyl)sulfonyl]amino] (methylimino)methyl]-N2-[ (9H-fluoren-9-ylmethoxy)carbonyl]-L-ornithine; Fmoc-Arg(Me, Pbf)-OH; (2S) -2- (9H-fluoren-9-ylmethoxycarbonylamino) -5- [ [N \ '-methyl-N- [ (2, 2, 4, 6, 7-pentamethyl-3H-1-benzofuran-5-yl) sulfonyl] carbamimidoyl] amino] pentanoic acid; (S,E)-12-(9H-fluoren-9-yl)-10-oxo-3-(2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-ylsulfonylimino)-11-oxa-2,4,9-triazadodecane-8-carboxylicacid; (S, E) -2- ( ( ( (9H-fluoren-9-yl) methoxy) carbonyl) amino) -5- ( ( (methylamino) (2, 2, 4, 6, 7-pentamethyl-2, 3-dihydrobenzofuran-5-sulfonamido) methylene) amino) pentanoic acid; N-alpha-(9-Fluorenylmethoxycarbonyl)-N-omega1-methyl-N-omega2-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine. Grades: ≥ 99.2% (Chiral HPLC). CAS No. 1135616-49-7. Molecular formula: C35H42N4O7S. Mole weight: 662.80.
Picrolichenic acid
It is a 3-spirobenzofuran heterocyclic compound isolated from Variolaria amara. Synonyms: 6-Hydroxy-2'-methoxy-2,4'-dioxo-4,6'-dipentylspiro[benzofuran-3(2H),1'-[2,5]cyclohexadiene]-5-carboxylicacid; Pikrolichenic acid; Spiro[benzofuran-3(2H),1'-[2,5]cyclohexadiene]-5-carboxylicacid, 6-hydroxy-2'-methoxy-2,4'-dioxo-4,6'-dipentyl-; picrolichenin; NSC 43331; 6-hydroxy-2'-methoxy-2,4'-dioxo-4,6'-dipentyl-2H-spiro[benzofuran-3,1'-cyclohexane]-2',5'-diene-5-carboxylicacid. CAS No. 466-34-2. Molecular formula: C25H30O7. Mole weight: 442.50.
Przewalskinic acid A
Przewalskinic acid A is found in the Salvia przewalskii Maxim herb. Synonyms: Przewalskinic acid A; 136112-75-9; (2R,3R)-4-[(E)-2-carboxyethenyl]-2-(3,4-dihydroxyphenyl)-7-hydroxy-2,3-dihydro-1-benzofuran-3-carboxylicacid; 7-Epiblechnic acid; HY-N5057. Grades: >98%. CAS No. 136112-75-9. Molecular formula: C18H14O8. Mole weight: 358.3.
Silvestrol aglycone
Silvestrol aglycone, extracted from Aglaia foveolata, could induce apoptosis in LNCaP cells through the mitochondrial/apoptosome pathway without activation of executioner caspase-3 or -7; 5'myc-UTR-LUC inhibtior with IC50 value of 0.8 nM. It is a aglycone with potential anticancer rocaglate. lt induced an apoptotic response, disrupted the mitochondrial trans-membrane potential and caused cytochrome c release into the cytoplasm in vitro. It produced an increase of Bcl-xl phosphorylation with a concomitant increase of bak at the protein level. It selectively inhibit the translation of proteins by a cellular reporter assay. It have similar cytotoxic potency and better ADME characteristics relative to those of silvestrol. Uses: Silvestrol aglycone is a aglycone with potential anticancer rocaglate. Synonyms: (1R,2R,3S,3aR,8bS)-2,3,3a,8b-Tetrahydro-1,6,8b-trihydroxy-8-methoxy-3a-(4-methoxyphenyl)-3-phenyl-1H-cyclopenta[b]benzofuran-2-carboxylicacid methyl ester;Methyl (1R,2R,3S,3aR,8bS)-1,6,8b-trihydroxy-8-methoxy-3a-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxylate. Grades: >98 %. CAS No. 960365-65-5. Molecular formula: C27H26O8. Mole weight: 478.49.
Talniflumate
Talniflumate is a calcium-activated chloride channel (CaCC) (hCLCA1/mCLCA3) blocker. It decreases mucin synthesis and release in cell culture and animal models. Talniflumate inhibits cyclooxygenases and Cl-/HCO3- exchanger activity to produce anti-inflammatory actions. Talniflumate also increases survival in a cystic fibrosis mouse model of distal intestinal obstructive syndrome. Uses: Anti-inflammatory agent. Synonyms: 2-[[3-(Trifluoromethyl)phenyl]amino]-1,3-dihydro-3-oxo-1-isobenzofuranyl 3-pyridinecarboxylicacid ester; Somalgen; Lomucin; (3-oxo-1H-2-benzofuran-1-yl) 2-[3-(trifluoromethyl)anilino]pyridine-3-carboxylate. Grades: ≥99% by HPLC. CAS No. 66898-62-2. Molecular formula: C21H13F3N2O4. Mole weight: 414.34.
Vilazodone CarboxylicAcid
Vilazodone CarboxylicAcid. Uses: For analytical and research use. Group: Impurity standards. CAS No. 163521-19-5. Pack Sizes: 2.5MG. IUPAC Name: 5-[4-[4-(5-cyano-1H-indol-3-yl)butyl]piperazin-1-yl]-1-benzofuran-2-carboxylicacid. Molecular Formula: C26H26N4O3. Mole Weight: 442.51. Catalog: APS163521195. SMILES: OC (=O)c1oc2ccc (cc2c1)N3CCN (CCCCc4c[nH]c5ccc (cc45)C#N)CC3. Format: Neat. Shipping: Room Temperature.
6-Carboxyfluorescein N-succinimidyl ester
6-Carboxyfluorescein N-succinimidyl ester is the amine-reactive succinimidyl ester carboxyfluorescein that is used in the labeling of nucleotides and nucleic acids. Synonyms: FAM NHS ester, 6-isomer;OSu-FAM; 6-FAM, SE; 6-FAM SE; 6-Carboxyfluorescein-NHS; 6-Carboxyfluorescein N-hydroxysuccinimide ester; (2,5-dioxopyrrolidin-1-yl) 3',6'-dihydroxy-1-oxospiro[2-benzofuran-3,9'-xanthene]-5-carboxylate. Grades: NMR 1H, HPLC-MS (95%). CAS No. 92557-81-8. Molecular formula: C25H15NO9. Mole weight: 473.393.