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Intermediate in the preparation of Fentanyl derivatives. Group: Biochemicals. Alternative Names: 1-Benzyl-4- (phenylamino) piperidine; 1-Benzyl-4-anilinopiperidine; N-Phenyl-1-(phenylmethyl)-4-piperidinamine; NSC 76613. Grades: Highly Purified. CAS No. 1155-56-2. Pack Sizes: 10mg. US Biological Life Sciences.
Methyl 4-amino-1-benzylpiperidine-4-carboxylate. Group: Biochemicals. Grades: Highly Purified. CAS No. 57611-57-1. Pack Sizes: 25mg, 50mg. Molecular Formula: C14H20N2O2, Molecular Weight: 248.32. US Biological Life Sciences.
Worldwide
1-Benzyl-4-piperidinol
1-Benzyl-4-piperidinol. Group: Biochemicals. Alternative Names: 1-(Phenylmethyl)-4-piperidinol; 4-Hydroxy-1-benzylpiperidine; 4-Hydroxy-N-benzylpiperidine. Grades: Highly Purified. CAS No. 4727-72-4. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C12H17NO. US Biological Life Sciences.
Worldwide
1-Benzyl-isonipecotic acid
1-Benzyl-isonipecotic acid. Group: Biochemicals. Alternative Names: 1-Benzylpiperidine-4-carboxylic acid. Grades: Highly Purified. CAS No. 10315-07-8. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C12H17NO3. US Biological Life Sciences.
Worldwide
1-(Phenylmethyl)-4-piperidinamine
1-(Phenylmethyl)-4-piperidinamine. Group: Biochemicals. Alternative Names: (1-Benzylpiperidin-4-yl)amine; 1-(Phenylmethyl)-4-piperidinamine; 1-Benzyl-4-aminopiperidine; 1-Benzyl-4-piperidinamine; 1-Benzyl-4-piperidinylamine; 1-Benzylpiperidine-4-amine; 2-Amino-1-benzylpiperidine; 4-Amino-1- (phenylmethyl) piperidine; 4-Amino-1-benzylpiperidine; 4-Amino-N-benzylpiperidine; N-Benzyl-4-aminopiperidine; N-Benzyl-4-piperidinamine. Grades: Highly Purified. CAS No. 50541-93-0. Pack Sizes: 5g. Molecular Formula: C12H18N2, Molecular Weight: 190.28. US Biological Life Sciences.
Worldwide
2-Fluorotoluene-α-d1
2-Fluorotoluene-α-d1 is labelled 2-Fluorotoluene which was used in the study of E2020 as a potent acetylcholinesterase (AChE) inhibitor. It was also used to study substituted indanone and benzylpiperidine ring substructures of a set of AChE inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 17359-78-3. Pack Sizes: 50mg, 250mg. Molecular Formula: C7H6DF, Molecular Weight: 111.14. US Biological Life Sciences.
A labeled piperidine derivative as potential analgesic agents. Group: Biochemicals. Alternative Names: 1-Benzyl-4-[(phenyl-13C6)-amino]piperidine-4-carboxylic Acid; 4-(Anilino-13C6)-1-benzylpiperidine-4-carboxylic Acid; NSC 73748-13C6. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
4-(Phenylamino)-1-benzyl-4-piperidinecarbonitrile
Used as modulators of muscarinic receptors for treatment of CNS disorders. Group: Biochemicals. Alternative Names: 1-Benzyl-4- (phenylamino) piperidine-4-carbonitrile; 1-Benzyl-4-cyano-4-anilinopiperidine; 4-Anilino-4-cyano-1-benzylpiperidine; NSC 73005. Grades: Highly Purified. CAS No. 968-86-5. Pack Sizes: 250mg. US Biological Life Sciences.
Used as modulators of muscarinic receptors for treatment of CNS disorders. Group: Biochemicals. Alternative Names: 1-Benzyl-4-[(phenyl-13C6)-amino]piperidine-4-carbonitrile; 1-Benzyl-4-cyano-4-(anilino-13C6)piperidine; 4-(Anilino-13C6)-4-cyano-1-benzylpiperidine; NSC 73005-13C6. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences.
A piperidine derivative as potential analgesic agent. Group: Biochemicals. Alternative Names: 1-Benzyl-4- (phenylamino) piperidine-4-carboxylic Acid; 4-Anilino-1-benzylpiperidine-4-carboxylic Acid; NSC 73748. Grades: Highly Purified. CAS No. 85098-64-2. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
Anamorelin Impurity 1
Anamorelin Impurity 1. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-3-benzylpiperidine-3-carboxylic acid. Molecular Formula: C13H17NO2. Mole Weight: 219.28. Catalog: APB02923.
Ifenprodil
Ifenprodil is an NMDA receptor antagonist and acts at the polyamine site. It is also an α2 adrenergic receptor ligand. It is selective for σ2 ligand over σ1 sites. It is used as a neuroprotective agent and peripheral vasodilator. Uses: Excitatory amino acid antagonists. Synonyms: 4-[2-(4-Benzylpiperidin-1-yl)-1-hydroxypropyl]phenol; (1R*,2S*)-erythro-2-(4-Benzylpiperidino)-1-(4-hydroxyphenyl)-1-propanol; α-(4-Hydroxyphenyl)-β-methyl-4-(phenylmethyl)-1-piperidineethanol; 1-Methyl-2-hydroxy-2-(4-hydroxyphenyl)ethyl-1-(4-benzylpiperidine); 2-(4-Benzylpiperidino)-1-(1-hydroxyphenyl)-1-propanol; RC 61-91. Grades: ≥99% by HPLC. CAS No. 23210-56-2. Molecular formula: C21H27NO2. Mole weight: 325.44.
JX 401
JX 401, cell-permeable piperidinamide compound, is a reversible and highly potent inhibitor of p38α isoform MAP kinase containing a 4-benzylpiperidine motif. Its IC50 value is 32 nM and displays no activity on the p38γ isoform. It effectively blocks the differentiation of L8 myoblasts to myotubes in a reversible manner and blocks the differentiation of myoblasts and myotubes in mammalian cells in culture. It is not a competitive inhibitor with respect to either ATP or substrate. It is hyperactive in inflammatory diseases and may reverse inflammation. Synonyms: JX-401; JX 401; JX401; 1-[2-Methoxy-4-(methylthio)benzoyl]-4-(phenylmethyl)piperidine; [2-Methoxy-4-(methylthio)phenyl][4-(phenylmethyl)-1-piperidinyl]-methanone; N-(2-Methoxy-4-thiomethyl)benzoyl-4-benzylpiperidine. Grades: ≥98% by HPLC. CAS No. 349087-34-9. Molecular formula: C21H25NO2S. Mole weight: 355.49.
KT203
KT203 is a potent inhibitor of α/β-hydrolase domain-containing protein 6 (ABHD6). ABHD6 is a transmembrane serine hydrolase hydrolyzing transmembrane serine hydrolase in nervous system. ABHD6 inhibition was shown to decrease seizure incidence in several mouse models of epilepsy, suggesting its potential for Dravet Syndrome treatment. Synonyms: ML-296; 3-[4-[1-(2-Benzylpiperidine-1-carbonyl)triazol-4-yl]phenyl]benzoic acid. Grades: ≥95%. CAS No. 1402612-64-9. Molecular formula: C28H26N4O3. Mole weight: 466.5.
N-Benzyl-4-carboethoxypiperidine
N-Benzyl-4-carboethoxypiperidine. Group: Biochemicals. Alternative Names: 1-(Phenylmethyl)-4-piperidinecarboxylic Acid Ethyl Ester; 1- (Phenylmethyl) piperidine-4-carboxylic Acid Ethyl Ester; Ethyl 1-Benzylisonipecotate; Ethyl 1-Benzylpiperidine-4-carboxylate. Grades: Highly Purified. CAS No. 24228-40-8. Pack Sizes: 10g. US Biological Life Sciences.
Worldwide
(Piperidinomethyl)polystyrene)
extent of labeling: ~3.5 mmol/g base loading. Uses: (piperidinomethyl)polystyrene is a solid supported reagent (ssr) that can be used as an acid-scavenger in solid phase organic synthesis (spos). Group: Polystyrene (ps). Alternative Names: 1-Benzylpiperidine polymer-bound; Copolymer of styrene and divinylbenzene, piperidinomethylated; Piperidine, polymer-bound; Polystyrene crosslinked with divinylbenzene, piperidinomethylated.
Intermediate used in the preparation p-38 kinase inhibitors and serotonin antagonists. Group: Biochemicals. Alternative Names: [1-(Phenylmethyl)-4-piperidinyl]carbamic Acid Phenylmethyl Ester; [1-(Benzyl)-4-piperidinyl]carbamic Acid Benzyl Ester; Benzyl (1-Benzylpiperidin-4-yl)carbamate; N-(Benzyloxycarbonyl)-1-benzylpiperidin-4-ylamine. Grades: Highly Purified. CAS No. 182223-53-6. Pack Sizes: 500mg. US Biological Life Sciences.
1-Benzylpiperidin-4-yl 2-methylbut-3-enoate is an impurity in the synthesis of (+)-Echimidine N-Oxide, which is a hepatotoxic pyrrolizidine alkaloid. Different extracts and echimidine-N-oxide from Symphytum sylvaticum Boiss. Subsp. sepulcrale, has been shown to have Antifungal activity. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C17H23NO2. US Biological Life Sciences.
Worldwide
(1-Benzylpiperidin-4-yl)diphenyl-d10-methanol
(1-Benzylpiperidin-4-yl)diphenyl-d10-methanol is an intermediate in the synthesis of Fexofenadine-d10 Hydrochloride, the labeled analogue of Fexofenadine Hydrochloride (F322490), the active metabolite of Terfenadine (T114500), a H1-histamine receptor antagonist. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 100mg. Molecular Formula: C25H17D10NO, Molecular Weight: 367.55. US Biological Life Sciences.
2-(3-(1-Benzylpiperidin-4-yl)-2-oxopropyl)-4,5-dimethoxybenzoic Acid Benzyl Ester is an impurity of Donepezil (D531750), an inhibitor of acetylcholinesterase. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 5mg. Molecular Formula: C31H35NO5. US Biological Life Sciences.
2-(3-(1-Benzylpiperidin-4-yl)-2-oxopropyl)-4,5-dimethoxybenzoic Acid Benzyl Ester is one of Donepezil impurities. Donepezil, a highly specific reversible acetylcholinesterase (AChE) inhibitor, is used to treat moderate to severe Alzheimer's disease. Molecular formula: C31H35NO5. Mole weight: 501.61.
An impurity of Donepezil. Group: Biochemicals. Alternative Names: 4, 5-Dimethoxy-2- [2-oxo-3- [1- (phenylmethyl) -4-piperidinyl] propyl] benzoic Acid. Grades: Highly Purified. CAS No. 197010-25-6. Pack Sizes: 1mg. US Biological Life Sciences.
2,3-Dihydro-2-hydroxy-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-inden-1-one is one of Donepezil analogues. Donepezil, a highly specific reversible acetylcholinesterase (AChE) inhibitor, is used to treat moderate to severe Alzheimer's disease. Synonyms: 1-benzyl-4-[(5,6-dimethoxy-2-hydroxy-1-indanon)-2-yl]methylpiperidine; 2-[(1-benzylpiperidin-4-yl)methyl]-2-hydroxy-5,6-dimethoxy-3H-inden-1-one; 2-Hydroxy-2-[(1-benzyl-4-piperidinyl)methyl]-5,6-dimethoxyindan-1-one; 1H-Inden-1-one, 2,3-dihydro-2-hydroxy-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-. Grades: ≥95%. CAS No. 329010-67-5. Molecular formula: C24H29NO4. Mole weight: 395.49.
3-Hydroxy Donepezil is one of Donepezil impurities. Donepezil, a highly specific reversible acetylcholinesterase (AChE) inhibitor, is used to treat moderate to severe Alzheimer's disease. Synonyms: 2-((1-Benzylpiperidin-4-yl)methyl)-3-hydroxy-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one. Grades: > 90%. CAS No. 2097683-67-3. Molecular formula: C24H29NO4. Mole weight: 395.50.
(4- (1-Benzylpiperidin-4-Yloxy) -2-Chlorophenyl) Methanamine Dihydrochloride. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g. US Biological Life Sciences.
Worldwide
4-IBP
4-IBP, an agonist that specially targets sigma receptor (IC50= 1.7 nM), induced marked concentration-dependent decreases in the growth of human cancer cells. Synonyms: N-(1-benzylpiperidin-4-yl)-4-iodobenzamide; (125I)-N-(N-benzylpiperidin-4-yl)-4-iodobenzamide; 4-IBP cpd; BPIBA; N-(N-benzylpiperidin-4-yl)-4-iodobenzamide. CAS No. 155798-08-6. Molecular formula: C19H21IN2O. Mole weight: 420.29.
5-Desmethoxy-7-methoxy Donepezil Hydrochloride is a derivative of Donepezil, which is a highly specific reversible acetylcholinesterase (AChE) inhibitor used to treat moderate to severe Alzheimer's disease. Synonyms: 2-((1-Benzylpiperidin-4-yl)methyl)-6,7-dimethoxy-2,3-dihydro-1H-inden-1-one hydrochloride; 2,3-Dihydro-6,7-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-inden-1-one Hydrochloride; 2-[(1-Benzyl-4-piperidinyl)methyl]-6,7-dimethoxy-1-indanone hydrochloride (1:1); 1H-Inden-1-one, 2,3-dihydro-6,7-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-, hydrochloride (1:1). Grades: 98%. CAS No. 120013-51-6. Molecular formula: C24H29NO3.HCl. Mole weight: 415.95.
6-O-Desmethyl Donepezil Glucuronide Sodium Salt (Mixture of Diastereomers)
6-O-Desmethyl Donepezil Glucuronide Sodium Salt (Mixture of Diastereomers) is one of Donepezil impurities. Donepezil, a highly specific reversible acetylcholinesterase (AChE) inhibitor, is used to treat moderate to severe Alzheimer's disease. Synonyms: (2S,3S,4S,5R,6S)-6-((2-((1-benzylpiperidin-4-yl)methyl)-6-methoxy-3-oxo-2,3-dihydro-1H-inden-5-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid, sodium salt (1:1). Molecular formula: C29H34NO9.Na. Mole weight: 563.57.
AdipoRon
AdipoRon is a novel small-molecule AdipoR agonist, binding to both AdipoR1(Kd=1.8 μM) and AdipoR2(Kd=3.1 μM). Synonyms: AdipoRon; 924416-43-3; 2-(4-benzoylphenoxy)-N-(1-benzylpiperidin-4-yl)acetamide; SC-396658; ND7UVH6GKJ. Grades: >98%. CAS No. 924416-43-3. Molecular formula: C27H28N2O3. Mole weight: 428.52.
Benidipine
Benidipine. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 91599-74-5(HCl); rel-3-((R)-1-benzylpiperidin-3-yl) 5-methyl (R)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate. Molecular Formula: C28H31N3O6. Mole Weight: 505.56. Catalog: APB03650.
Benidipine 5-(1-Benzylpiperidin-3-yl)
Benidipine 5-(1-Benzylpiperidin-3-yl) is an impurity of Benidipine (B157500), a dihydropyridine calcium channel blocker. Antihypertensive. Group: Biochemicals. Grades: Highly Purified. CAS No. 91599-75-6. Pack Sizes: 10mg, 25mg. Molecular Formula: C39H44N4O6, Molecular Weight: 664.79. US Biological Life Sciences.
Worldwide
Benidipine Impurity 10 (Dihydrochloride)
Benidipine Impurity 10 (Dihydrochloride). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: bis(1-benzylpiperidin-3-yl) 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate dihydrochloride. Molecular Formula: C39H44N4O6·2HCl. Mole Weight: 737.71. Catalog: APB03642.
Benidipine Impurity 12 (Hydrochloride)
Benidipine Impurity 12 (Hydrochloride). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (SR)-3-((RS)-1-benzylpiperidin-3-yl) 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride. Molecular Formula: C28H31N3O6·HCl. Mole Weight: 542.02. Catalog: APB03640.
Benidipine Impurity 13 (Hydrochloride)
Benidipine Impurity 13 (Hydrochloride). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-3-((R)-1-benzylpiperidin-3-yl) 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride. Molecular Formula: C28H31N3O6·HCl. Mole Weight: 542.02. Catalog: APB03639.
Benidipine Impurity 14 (Hydrochloride)
Benidipine Impurity 14 (Hydrochloride). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-3-((S)-1-benzylpiperidin-3-yl) 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride. Molecular Formula: C28H31N3O6·HCl. Mole Weight: 542.02. Catalog: APB03638.
Benidipine Impurity 3 (Dihydrochloride)
Benidipine Impurity 3 (Dihydrochloride). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: bis((R)-1-benzylpiperidin-3-yl) 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate dihydrochloride. Molecular Formula: C39H44N4O6·2HCl. Mole Weight: 737.71. Catalog: APB03648.
Benidipine Impurity 6
Benidipine Impurity 6. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-(1-benzylpiperidin-3-yl) 5-methyl 2,6-dimethyl-4-(3-nitrosophenyl)pyridine-3,5-dicarboxylate. Molecular Formula: C28H29N3O5. Mole Weight: 487.55. Catalog: APB03647.
Benidipine Impurity 7
Benidipine Impurity 7. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-(1-benzylpiperidin-3-yl) 5-methyl 4-(3-aminophenyl)-2,6-dimethylpyridine-3,5-dicarboxylate. Molecular Formula: C28H31N3O4. Mole Weight: 473.23. Catalog: APB03645.
Benidipine Impurity 9
Benidipine Impurity 9. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-3-((R)-1-benzylpiperidin-3-yl) 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate. Molecular Formula: C28H31N3O6. Mole Weight: 505.56. Catalog: APB03644.
Benzetimide hydrochloride
Benzetimide hydrochloride is a muscarinic acetylcholine receptor antagonist that has anticholinergic properties and could block pilocarpine-induced lacrimation. Uses: Amuscarinic acetylcholine receptor antagonist. Synonyms: R 4929; R4929; R-4929Spasmentral;3-(1-benzylpiperidin-4-yl)-3-phenylpiperidine-2,6-dione;hydrochloride. Grades: ≥98%. CAS No. 5633-14-7. Molecular formula: C23H26N2O2.HCl. Mole weight: 398.93.
BIX 01294 trihydrochloride
BIX 01294 is a G9a histone methyltransferase inhibitor. It enhances the induction of pluripotent stem cells from somatic cells in vitro. BIX-01294 trihydrochloride induces necroptosis and autophagy. Synonyms: BIX 01294 trihydrochloride; BIX-01294; N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine trihydrochloride. Grades: >98%. CAS No. 1392399-03-9. Molecular formula: C28H41Cl3N6O2. Mole weight: 600.02.
BRN-103
BRN-103 can suppress the phosphorylation of vascular endothelial growth factor (VEGF) receptor 2. It can also inhibit the activations of AKT and eNOS. These results show that BRN-103 inhibits VEGF-mediated angiogenesis signaling in human endothelial cells. Synonyms: BRN103; BRN103; BRN 103; 2-((1-benzylpiperidin-4-yl)amino)-N-(3-chlorophenyl)nicotinamide. Grades: 98%. CAS No. 1346265-80-2. Molecular formula: C24H25ClN4O. Mole weight: 420.93.
A cell-permeable (bis-benzylidene) piperidinone compound that acts as a selective inhibitor against CARM1/PRMT4 arginine methyltransferase activity (IC50=7.1uM with PABP1 as substrate). It inhibits PRMT3 only at much higher concentrations (by 70% and 62% with 100uM inhibitor using NPL3 or rpS2 as substrate, respectively), exhibiting little activity against PRMT1, PRMT5, PRMT6 (IC50>100uM), or four HKMTs (<20% inhibition against DOTL1, G9a, SET7, or Suv39H1 with 100uM inhibitor). Shown to inhibit PSA promoter-mediated reporter transcription in LNCaP cells in a dose-dependent manner (by 74% and 97%, respectively, with 4 and 6uM inhibitor). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Clebopride Malate
Clebopride is a substituted benzamide as a dopamine antagonist used to treat functional gastrointestinal disorders. Uses: Dopamine antagonist. Synonyms: 4-Amino-5-chloro-2-methoxy-N-(1-benzyl-4-piperidyl)benzamide malate; 4-amino-N-(1-benzylpiperidin-1-ium-4-yl)-5-chloro-2-methoxybenzamide;2,4-dihydroxy-4-oxobutanoate. Grades: ≥95%. CAS No. 57645-91-7. Molecular formula: C23H28ClN3O6. Mole weight: 477.94.
Dehydro Benidipine
Dehydro Benidipine is an impurity of Benidipine. Synonyms: 2,6-Dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-Methyl 5-[1-(Phenylmethyl)-3-piperidinyl] Ester; DH 124; 3-(1-Benzylpiperidin-3-yl) 5-Methyl 2,6-Dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate. Grades: > 95%. CAS No. 118935-44-7. Molecular formula: C28H29N3O6. Mole weight: 503.56.
Dehydro Benidipine (Hydrochloride)
Dehydro Benidipine (Hydrochloride). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 118935-44-7(free base); 3-(1-benzylpiperidin-3-yl) 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate hydrochloride. Molecular Formula: C28H29N3O6·HCl. Mole Weight: 542.02. Catalog: APB03641.
Donepezil
Donepezil, also called Aricept, a centrally acting reversible acetyl cholinesterase inhibitor that the FDA has also approved for the treatment of moderate to severe Alzheimer's disease. It readily crosses the blood-brain barrier to reduce the breakdown of acetylcholine by increasing the concentration of acetylcholine through reversible inhibition of its hydrolysis by acetylcholinesterase. Synonyms: 2,3-Dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-inden-1-one; (±)-E 2020; 1-Benzyl-4-[(5,6-dimethoxy-1-oxoindan-2-yl)methyl]piperidine; Neuripezil; Tonizep; 2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one; Aricept; HSDB 7743; HSDB7743; HSDB-7743; 1-benzyl-4-((5,6-dimethoxy-1-indanon)-2-yl)methylpiperidine hydrochloride; 2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one; Eranz; Aricept ODT; donepezilo; donepezilum; CHEMBL502; donepezil hydrochloride; donepezilium oxalate trihydrate; E 2020; E-2020; E2020; 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one; (RS)-2-[(1-BENZYL-PIPERIDIN-4-YL)METHYL]-5,6-DIMETHOXYINDAN-1-ONE. Grades: > 98%. CAS No. 120014-06-4. Molecular formula: C24H29NO3. Mole weight: 379.49.
(-)-Donepezil
(-)-Donepezil is one of Donepezil isomers. Donepezil, a highly specific reversible acetylcholinesterase (AChE) inhibitor, is used to treat moderate to severe Alzheimer's disease. Uses: Cholinesterase inhibitors; nootropic agents. Synonyms: (S)-2,3-Dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-Inden-1-one; (2S)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one; (S)-Donepezil; (S)-Aricept; (2S)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one. Grades: ≥95%. CAS No. 142057-80-5. Molecular formula: C24H29NO3. Mole weight: 379.49.
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