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Used in the preparation of neurologically active agents and other pharmaceutical compounds. Synonyms: 1-Boc-4-piperidinol; 4-Hydroxy-piperidine-1-carboxylic acid tert-butyl ester. Grades: ≥ 99 % (GC). CAS No. 109384-19-2. Molecular formula: C10H19NO3. Mole weight: 201.27.
Boc-(4-hydroxy)piperidine 99+% (GC)
Boc-(4-hydroxy)piperidine 99+% (GC). Group: Biochemicals. Grades: GC. CAS No. 109384-19-2. Pack Sizes: 1g, 5g, 25g, 100g, 250g. US Biological Life Sciences.
Sigma-LIGAND-1, also called as NPC 16377, is a selective sigma receptor ligand developed for the treatment of neurological disorders and psychotic disorders in the past. NPC 16377 has receptor IC50s of 16 nM at the DTG site, 19 nM at the PPP site, and a Ki of 4000 nM at the dopamine D2 receptor. Synonyms: 6-[6-(4-hydroxypiperidin-1-yl)hexoxy]-3-methyl-2-phenylchromen-4-one; 6-(6-(4-hydroxypiperidinyl)hexyloxy)-3-methylflavone hydrochloride; NPC 16377; NPC-16377; NPC16377. CAS No. 139652-01-0. Molecular formula: C27H33NO4. Mole weight: 435.56.
[4-Hydroxy-1-methyl-4-(2-thienyl)-3-piperidinyl]-2-thienylmethanone Hydrochloride is an impurity of Duloxetine, which is a serotonin-norepinephrine reuptake inhibitor used to treat major depressive disorder, generalized anxiety disorder, fibromyalgia, neuropathic pain and central sensitization. Synonyms: Methanone, [4-hydroxy-1-methyl-4-(2-thienyl)-3-piperidinyl]-2-thienyl-, monohydrochloride; Methanone, [4-hydroxy-1-methyl-4-(2-thienyl)-3-piperidinyl]-2-thienyl-, hydrochloride (1:1). CAS No. 494221-40-8. Molecular formula: C15H18ClNO2S2. Mole weight: 343.89.
4-Hydroxy Thalidomide
A metabolite of Thalidomide which was prescribed as an anti-nausea agent to help pregnant women with morning sickness but withdrawn from the market when it was discovered to cause birth defects. Synonyms: 4-Hydroxy thalidomide; E3 ligase Ligand 2; 2-(2,6-dioxopiperidin-3-yl)-4-hydroxyisoindoline-1,3-dione; 4-Hydroxythalidomide; Thalidomide-4-OH; 2-(2,6-dioxopiperidin-3-yl)-4-hydroxyisoindole-1,3-dione; 2-(2,6-Dioxo-3-piperidinyl)-4-hydroxyisoindoline-1,3-dione; 4-Hydroxy-thalidomide; 4-Hydroxy thalidomide, (+/-)-; E3 ligase Ligand 2 (Thalidomide-OH); J344NHC6VB; C13H10N2O5; MFCD03699892; Phthalimide, N-(2,6-dioxo-3-piperidyl)-3-hydroxy-; 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-hydroxy-; 2-(2,6-dioxopiperidin-3-yl)-4-hydroxy-2,3-dihydro-1H-isoindole-1,3-dione;2-(2,6-Dioxo-piperidin-3-yl)-4-hydroxy-isoindole-1,3-dione; 2-(2,6-dioxo-piperidine-3-yl)-4-hydroxy-isoindole-1,3-dione; 4-hydroxy-2-(2,6-dioxo(3-piperidyl))isoindoline-1,3-dione. Grades: > 95%. Molecular formula: C13H10N2O5. Mole weight: 274.24.
CP-283097
CP-283097 is NR2B N-Methyl-D-Aspartate receptor antagonist originated by Pfizer. Preclinical trials for the treatment of Migraine and Neurodegenerative disorders were discontinued. Uses: Migraine; neurodegenerative disorders. Synonyms: CP-283097; CP283097; CP 283097; UNII-WHL1Z3GN15;;(3R,4S)-Rel-3,4-dihydro-3-(4-hydroxy-4-(phenylmethyl)-1-piperidinyl)-2H-1-benzopyran-4,7-diol. Grades: 98%. CAS No. 138047-56-0. Molecular formula: C21H25NO4. Mole weight: 355.43.
Dechloro Haloperidol
Dechloro Haloperidol is also known as Haloperidol impurity B. Synonyms: 1-(4-Fluorophenyl)-4-(4-Hydroxy-4-Phenyl-1-Piperidyl)Butan-1-One; 1-(4-Fluorophenyl)-4-(4-hydroxy-4-phenyl-1-piperidinyl)-1-butanone; 4'-Fluoro-4-(4-hydroxy-4-phenylpiperidino)butyrophenone; Haloperidol impurity B; R 1838. Grades: > 95%. CAS No. 3109-12-4. Molecular formula: C21H24FNO2. Mole weight: 341.42.
Fexofenadine USP Related Compound B is an impurity of Fexofenadine, which is a histamine H1 receptor antagonist used for the treatment of allergy symptoms, such as hay fever, nasal congestion, and urticaria. Synonyms: USP Fexofenadine Related Compound B; 3-[1-Hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]butyl]-α,α-dimethyl benzeneacetic acid hydrochloride monohydrate; 2-(3-{1-Hydroxy-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butyl}phenyl)-2-methylpropanoic acid hydrochloride monohydrate; Fexofenadine EP impurity B hydrochloride monohydrate; Benzeneacetic acid, 3-[1-hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]butyl]-α,α-dimethyl-, hydrochloride, hydrate (1:1:1); 2-[3-[(1RS)-1-Hydroxy-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butyl]phenyl]-2-methylpropanoic Acid Hydrochloride Monohydrate; 2-[3-(1-Hydroxy-4-{4-[hydroxy(diphenyl)methyl]-1-piperidinyl}butyl)phenyl]-2-methylpropanoic acid hydrochloride hydrate. Grades: ≥95%. Molecular formula: C32H39NO4.HCl.H2O. Mole weight: 556.13.
Flecainide Impurity C
An impurity of Flecainide. Flecainide is a class 1C antiarrhythmic drug especially used for the management of supraventricular arrhythmia. Synonyms: 4-Hydroxy Flecainide; 4-Hydroxy-N-(2-piperidinylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide; (±)-4-Hydroxy-N-(2-piperidinylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide. Grades: > 95%. CAS No. 152171-74-9. Molecular formula: C17H20F6N2O4. Mole weight: 430.35.
Ketotifen Impurity B
Ketotifen impurity, used in separation of enantiomers of Ketotifen and its polar intermediate by isotachophoresis. Synonyms: 4-Hydroxy-9,10-dehydro-10-methoxy Ketotifen; 10-Methoxy-4-(1-methyl-4-piperidinyl)-4H-benzo[4,5]cyclohepta[1,2-b]thiophene-4-ol. Grades: > 95%. CAS No. 59743-88-3. Molecular formula: C20H23NO2S. Mole weight: 341.48.
Ketotifen Impurity C
an intermediate in the synthesis of the 2-bromo derivative of Ketotifen. Synonyms: 4-Hydroxy Ketotifen; 4,9-Dihydro-4-hydroxy-4-(1-methyl-4-piperidinyl)-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one. Grades: > 95%. CAS No. 126939-27-3. Molecular formula: C19H21NO2S. Mole weight: 327.45.
ML-211
ML-211 is a dual inhibitor of LYPLA1 and the related LYPLA2 with IC50 of 17 and 30 nm. ML-211 could inhibit the serine hydrolase ABHD11 with IC50 of 10 nM but was over 50-fold selective for LYPLA in a panel of 20 additional serine hydrolases. Synonyms: Methanone, [4-(1,1-dimethylethyl)-1-piperidinyl][4-(hydroxydiphenylmethyl)-2H-1,2,3-triazol-2-yl]-; [4-(1,1-Dimethylethyl)-1-piperidinyl][4-(hydroxydiphenylmethyl)-2H-1,2,3-triazol-2-yl]methanone; {4-[Hydroxy(diphenyl)methyl]-2H-1,2,3-triazol-2-yl}[4-(2-methyl-2-propanyl)-1-piperidinyl]methanone; (4-(tert-butyl)piperidin-1-yl)(4-(hydroxydiphenylmethyl)-2H-1,2,3-triazol-2-yl)methanone. Grades: >98%. CAS No. 2205032-89-7. Molecular formula: C25H30N4O2. Mole weight: 418.53.
PKR-IN-2
PKR-IN-2 is a pyruvate kinase (PKR) activator. IC50: PKR (R510Q) <100 nM. Synonyms: N-[4-[4-hydroxy-4-(2-methylpropyl)piperidine-1-carbonyl]phenyl]quinoxaline-5-sulfonamide PKR-IN-2 SCHEMBL16049613. CAS No. 1628428-01-2. Molecular formula: C24H28N4O4S. Mole weight: 468.57.
(±)-PPCC oxalate
(±)-PPCC oxalate is a selective sigma (σ) receptor ligand, which is noted to exhibit high affinity for σ1 and also binds at σ2 sites (Ki = 1.5 nM and 50.8 nM respectively). Synonyms: (S*,R*)-2-[(4-Hydroxy-4-phenyl-1-piperidinyl)methyl]-1-(4-methylphenyl)-cyclopropanecarboxylic acid methyl ester; (1R,2S)-rel-2-[(4-Hydroxy-4-phenyl-1-piperidinyl)methyl]-1-(4-methylphenyl)-cyclopropanecarboxylic Acid Methyl Ester Ethanedioate (2:1). Grades: ≥99% by HPLC. CAS No. 932736-91-9. Molecular formula: C24H29NO3.C2H2O4. Mole weight: 469.53.