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| Product | Description | |
|---|---|---|
| Calcitonin gene-related peptide | Calcitonin gene-related peptide is a member of the calcitonin family of peptides consisting of calcitonin, amylin, adrenomedullin, adrenomedullin 2 (intermedin) and calcitonin - receptor - stimulating peptide. Synonyms: Calcitonin, pro-; CALCA protein, human; CALC1 protein, human; CGRP1 protein, human. CAS No. 83652-28-2. Molecular formula: C163H266N50O50S2. Mole weight: 3790.28. |  |
| Calcitonin gene-related peptide free acid | Calcitonin gene-related peptide (CGRP) free acid is the deamidated form of α-CGRP(human) (HY-P1071). Calcitonin gene-related peptide can be used to study the effect of C-terminal amidation on CGRP [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: CGRP free acid. CAS No. 83652-28-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P4058. |  |
| 1,3-Dihydro-1-(4-piperidinyl)-2H-imidazo[4,5-b]pyridin-2-one Dihydrochloride | 1,3-Dihydro-1-(4-piperidinyl)-2H-imidazo[4,5-b]pyridin-2-one is an intermediate used to prepare (3R,6S)-3-amino-6-(2,3-difluorophenyl)azepan-2-one of Telcagepant (MK-0974) for use as a calcitonin gene-related peptide receptor antagonist treating migraine headaches. Group: Biochemicals. Grades: Highly Purified. CAS No. 781649-84-1. Pack Sizes: 100mg, 500mg. Molecular Formula: C11H16Cl2N4O. US Biological Life Sciences. |  Worldwide |
| 1-(tert-Butyloxycarbonyl)-3-Fluoro-4-aminopiperidine | 1-(tert-Butyloxycarbonyl)-3-Fluoro-4-aminopiperidine is a reactant in the preparation of pharmaceutical compounds which are antagonists of CGRP (Calcitonin gene-related peptide) receptors and useful in the treatment of migraine. Group: Biochemicals. Grades: Highly Purified. CAS No. 934536-10-4. Pack Sizes: 100mg, 500mg. Molecular Formula: C10H19FN2O2, Molecular Weight: 218.27. US Biological Life Sciences. | Worldwide |
| (2R)-2-Amino-3-(4-aminophenyl)propanoic Acid | (2R)-2-Amino-3-(4-aminophenyl)propanoic Acid is an amino acid that is used as a reactant in the development of human calcitonin gene-related peptide (CGRP) receptor antagonists for treatment of acute migraine. Group: Biochemicals. Grades: Highly Purified. CAS No. 102281-45-8. Pack Sizes: 100mg, 250mg. Molecular Formula: C9H12N2O2. US Biological Life Sciences. | Worldwide |
| α-CGRP (8-37) (human) trifluoroacetate salt | Calcitonin gene-related protein (CGRP) is a neuropeptide. α-CGRP (8-37) is an antagonist of CGRP receptors. Synonyms: Calcitonin Gene-Related Peptide-1 (8-37) (human); CGRP-1 (8-37) (human); α-Calcitonin Gene-Related Peptide (8-37) (human). Grades: ≥95%. Molecular formula: C139H230N44O38·xCF3COOH. Mole weight: 3125.59. | |
| α-CGRP (human) | α-CGRP (human) is an endogenous calcitonin gene-related peptide receptor (CGRP) agonist. Synonyms: Calcitonin Gene Related Peptide; CGRP, human. CAS No. 90954-53-3. Molecular formula: C163H267N51O49S2. Mole weight: 3789.33. | |
| α-CGRP(human) | α-CGRP(human) (Calcitonin gene-related peptide) is a regulatory neuropeptide of 37 amino acids. α-CGRP(human) is widely distributed in the central and peripheral nervous system. α-CGRP(human) is a potent vasodilator and has inotropic and chronotropic effects [1] [2] [3]. Uses: Scientific research. Group: Peptides. Alternative Names: Calcitonin gene-related peptide. CAS No. 90954-53-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1071. | |
| α-CGRP (mouse, rat) | ?-CGRP (mouse, rat), a neuropeptide (calcitonin gene-related peptide (CGRP)) mainly expressed in neuromuscular junction, is a potent vasodilator. ?-CGRP (mouse, rat) can lead to a fall in blood pressure and an increase in heart rate by peripheral administration, also relax colonie smooth muscle. ?-CGRP (mouse, rat) has the potential in cardiovascular, pro-inflammatory, migraine and metabolic studies[1][2][3][4]. Uses: Scientific research. Group: Peptides. Alternative Names: CGRP (83-119), mouse, rat. CAS No. 83651-90-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P0203. | |
| β-CGRP, human | β-CGRP, human is a highly effective vasodilator. Synonyms: H-Ala-Cys-Asn-Thr-Ala-Thr-Cys-Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Met-Val-Lys-Ser-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Lys-Ala-Phe-NH2 (Disulfide bridge: Cys2-Cys7); Human β-CGRP; CGRP-II (Human); Calcitonin Gene Related Peptide II, human; α-Calcitonin gene-related peptide (human), 3-L-asparagine-22-L-methionine-25-L-serine-; β-Calcitonin gene-related peptide (human); L-Alanyl-L-cysteinyl-L-asparaginyl-L-threonyl-L-alanyl-L-threonyl-L-cysteinyl-L-valyl-L-threonyl-L-histidyl-L-arginyl-L-leucyl-L-alanylglycyl-L-leucyl-L-leucyl-L-seryl-L-arginyl-L-serylglycylglycyl-L-methionyl-L-valyl-L-lysyl-L-seryl-L-asparaginyl-L-phenylalanyl-L-valyl-L-prolyl-L-threonyl-L-asparaginyl-L-valylglycyl-L-seryl-L-lysyl-L-alanyl-L-phenylalaninamide cyclic (2?7)-disulfide; Human beta calcitonin gene-related peptide; Human calcitonin gene-related peptide 2; Human calcitonin gene-related peptide β; Human calcitonin gene-related peptide-II; Human calcitonin-related peptide II; Human β-calcitonin gene-related peptide. Grades: 95%. CAS No. 101462-82-2. Molecular formula: C162H267N51O48S3. Mole weight: 3793.35. | |
| β-CGRP (human) trifluoroacetate salt | β-Calcitonin gene-related peptide (β-CGRP) is a neuropeptide that binds selectively to a heteromeric complex of calcitonin receptor-like receptor (CRLR) and receptor activity-modifying protein 1 (RAMP1). Synonyms: Calcitonin Gene-Related Peptide-2 (human); β-Calcitonin Gene-Related Peptide (human); CGRP-2 (human). Grades: ≥95%. Molecular formula: C162H267N51O48S3·xCF3COOH. Mole weight: 3793.37. | |
| BMS694153 | BMS694153 is a potent and selective calcitonin gene-related peptide(CGRP) receptor antagonist. It is related with the pathogenesis of migraine. Uses: Bms694153 is related with the pathogenesis of migraine. Synonyms: BMS-694153; BMS 694153; BMS694153; (R)-N-(1-([1,4'-bipiperidin]-1'-yl)-3-(7-methyl-1H-indazol-5-yl)-1-oxopropan-2-yl)-4-(8-fluoro-2-oxo-1,4-dihydroquinazolin-3(2H)-yl)piperidine-1-carboxamide;(R)-4-(8-Fluoro-2-oxo-1,2-dihydroquinazolin-3(4H)-yl)-N-(3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-(piperidin-1-yl)piperidin-1-yl)propan-2-yl)piperidine-1-carboxamide;4-(8-Fluoro-2-oxo-1,4-dihydroquinazolin-3-yl)-N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]piperidine-1-carboxamide. Grades: >98 %. CAS No. 1050381-35-5. Molecular formula: C35H45FN8O3. Mole weight: 644.79. | |
| (±)-Boc-α-phosphonoglycine trimethyl ester | (±)-Boc-α-phosphonoglycine trimethyl ester is used as a reagent in the chemical synthesis of compounds such as Biphenomycin B, which is a potent antibiotic against Gram-neg., and imidazoles as potent calcitonin gene-related peptide (CGRP) antagonists. Synonyms: (±)-Trimethyl-Boc-α-phosphonoglycinate; (Dimethoxyphosphinyl)[[(1,1-dimethylethoxy)carbonyl]amino]acetic Acid Methyl Ester; 2-(Dimethoxyphosphinyl)-2-[[(1,1-dimethylethoxy)carbonyl]amino]acetic Acid Methyl Ester; Methyl 2-[(tert-butoxycarbonyl)amino]-2-(dimethoxyphosphoryl)acetate; (+/-)-Boc-alpha-phosphonoglycine trimethyl ester; N-Boc-2-Phosphonoglycine trimethyl ester; methyl 2-dimethoxyphosphoryl-2-[(2-methylpropan-2-yl)oxycarbonylamino]acetate; N-BUTOXYCARBONYL TRIMETHYLPHOSPHONOGLYCINE; Boc-GlyP(O)(OMe)2OMe; Boc-alpha-phosphonoglycine Trimethyl Ester. Grades: ≥ 98% (TLC). CAS No. 89524-98-1. Molecular formula: C10H20NO7P. Mole weight: 297.24. | |
| CGRP (rat) | α-CGRP (rat) is an endogenous neuropeptide displaying vasodilator, cardiovascular, pro-inflammatory and metabolic effects. Synonyms: Calcitonin Gene-Related Peptide (rat). Grades: >95%. CAS No. 83651-90-5. Molecular formula: C162H262N50O52S2. Mole weight: 3806.3. | |
| Eptinezumab | Eptinezumab is a humanized monoclonal antibody. Eptinezumab binds to calcitonin gene-related peptide (CGRP) and blocks its interaction with the receptor. Eptinezumab is used for the prevention of migraine in adults [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1644539-04-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99017. | |
| Eptinezumab | Eptinezumab is a humanized monoclonal antibody targeting calcitonin gene-related peptide (CGRP). Eptinezumab has been used for the preventive treatment of migraine in adults. Synonyms: Vyepti. CAS No. 1644539-04-7. | |
| Erenumab | Erenumab is a humanized monoclonal antibody targeting calcitonin gene-related peptide (CGRP). Erenumab has been used for the preventive treatment of migraines. Synonyms: Aimovig. CAS No. 1582205-90-0. | |
| Fremanezumab | Fremanezumab is a humanized monoclonal antibody targeting calcitonin gene-related peptide (CGRP). Fremanezumab has been investigated for the prevention of high-frequency episodic and chronic migraine. Synonyms: TEV-48125. CAS No. 1655501-53-3. | |
| Fremanezumab | Fremanezumab (TEV-48125) is a humanized IgG2a monoclonal antibody that selectively and potently binds to calcitonin gene-related peptide (CGRP). CGRP is a 37-amino acid neuropeptide involved in central and peripheral pathophysiological events of migraine. Fremanezumab has the potential for chronic migraine research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: TEV-48125. CAS No. 1655501-53-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99019. | |
| Galcanezumab | Galcanezumab is a humanized monoclonal antibody that selectively binds to calcitonin gene-related peptide (CGRP). Galcanezumab has the potential for the preventive treatment of chronic migraine. Synonyms: LY 2951742; LY2951742; LY-2951742. CAS No. 1578199-75-3. | |
| HCGRP-(8-37) | HCGRP-(8-37) is a human calcitonin gene-related peptide (hCGRP) fragment and also an antagonist of CGRP receptor. Uses: Scientific research. Group: Peptides. Alternative Names: Human ?-CGRP (8-37). CAS No. 119911-68-1. Pack Sizes: 500 ?g; 1 mg; 5 mg; 10 mg. Product ID: HY-P1014. | |
| HCGRP-(8-37) acetate | HCGRP-(8-37) acetate is the human calcitonin gene-related peptide (hCGRP) fragment and also an antagonist of CGRP1 receptors. Synonyms: H-Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asn-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Lys-Ala-Phe-NH2.CH3CO2H; L-valyl-L-threonyl-L-histidyl-L-arginyl-L-leucyl-L-alanyl-glycyl-L-leucyl-L-leucyl-L-seryl-L-arginyl-L-seryl-glycyl-glycyl-L-valyl-L-valyl-L-lysyl-L-asparagyl-L-asparagyl-L-phenylalanyl-L-valyl-L-prolyl-L-threonyl-L-asparagyl-L-valyl-glycyl-L-seryl-L-lysyl-L-alanyl-L-phenylalaninamide acetic acid; Human alpha-CGRP (8-37) acetate; 8-37-α-Calcitonin gene-related peptide (human) acetate; Human calcitonin gene-related peptide (8-37) acetate; Human CGRP(8-37) acetate; Human α-calcitonin gene-related peptide(8-37) acetate; Human α-CGRP (8-37) acetate. Grades: ≥95%. Molecular formula: C141H234N44O40. Mole weight: 3185.64. | |
| JYL1421 | JYL1421 is a TRPV1 receptor antagonist. JYL1421 concentration-dependently (0.1-2 mM) inhibited capsaicin-evoked substance P, calcitonin gene-related peptide and somatostatin release from isolated tracheae. It also concentration-dependently decreased capsaicin-induced Ca(2+) accumulation in cultured trigeminal ganglion cells. Synonyms: 3-[ (4-Tert-butylphenyl) methyl]-1-[ (3-fluoro-4-methanesulfonamidophenyl) methyl]thiourea. Grades: ≥95%. CAS No. 401907-26-4. Molecular formula: C20H26FN3O2S2. Mole weight: 423.6. | |
| MK-3207 | MK-3207 is a orally active and potent calcitonin gene-related peptide (CGRP) receptor antagonist IC50 vaule of 0.12 nM and Ki value of 0.024 nM. It is highly selective versus human AM1, AM2, CTR, and AMY3. It displays lower affinity for human CGRP receptors from other species, including canine and rodent. It is a potent antagonist of the human and rhesus monkey CGRP receptors in vitro. It produced a concentration-dependent inhibition of dermal vasodilation in vivo. It is effective acute migraine treatments. It was developed by Merck & Co., Inc. and was terminated in clinic phase 2. Uses: Mk-3207 is effective acute migraine treatments. Synonyms: MK3207; MK 3207; MK-3207; 2-[(8R)-8-(3,5-difluorophenyl)-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]-N-[(2R)-2'-oxospiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-5-yl]acetamide;(8R)-8-(3,5-Difluorophenyl)-10-oxo-N-[(2R)-1,1',2',3-tetrahydro-2'-oxospirv [4.5]decane-9-acetamide;6,9-Diazaspiro[4.5]decane-9-acetaMide,8-(3,5-difluorophenyl)-10-oxo-N-[(2R)-1,1',2',3-tetrahydro-2'-oxospiro[2H-indene-2,3'-[3H]pyrrolo[2,3-b]pyridin]-5-yl]-,(8R)-. Grades: >98 %. CAS No. 957118-49-9. Molecular formula: C31H29F2N5O3. Mole weight: 557.59. | |
| Olcegepant | Olcegepant, also called as BIBN4096BS or BIBN 4096, is the first potent and selective non-peptide antagonist of the calcitonin gene-related peptide 1 (CGRP1) receptor(IC50= 0.03 nM) and has been shown to block all effects of infused CGRP (2) and should ef. Synonyms: BIBN-4096; BIBN4096; BIBN 4096; BIBN-4096BS; BIBN4096BS; BIBN 4096BS; Olcegepant; N-[(2R)-1-[[(2S)-6-amino-1-oxo-1-(4-pyridin-4-ylpiperazin-1-yl)hexan-2-yl]amino]-3-(3,5-dibromo-4-hydroxyphenyl)-1-oxopropan-2-yl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide; Olcegepant; Olcegepant [INN]; BIBN-4096BS; BIBN 4096 BS; BIBN4096BS; CHEMBL2071; CHEMBL 2071; CHEMBL-2071. CAS No. 204697-65-4. Molecular formula: C38H47Br2N9O5. Mole weight: 869.65. | |
| Olcegepant | Olcegepant (BIBN-4096) is a potent and selective non-peptide antagonist of the calcitonin gene-related peptide 1 (CGRP1) receptor with IC50 of 0.03 nM and Ki of 14.4 pM for human CGRP[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BIBN-4096; BIBN 4096BS. CAS No. 204697-65-4. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-10095. | |
| Olcegepant | Olcegepant is a potent and selective calcitonin gene-related peptide (CGRP) receptor antagonist. Olcegepant displays high affinity for human CGRP receptors and exhibits no significant affinity for 75 other receptors. Olcegepant may a be viable option for the treatment of acute migraines. Group: Biochemicals. Alternative Names: 1-[3,5-Dibromo-N-[[4-(1,4-dihydro-2-oxo-3(2H)-quinazolinyl)-1-piperidinyl]carbonyl]-D-tyrosyl-L-lysyl]-4-(4-pyridinyl)piperazine; N- [ (1R) -2- [ [ (1S) -5-Amino-1- [ [4- (4-pyridinyl) -1-piperazinyl] carbonyl] pentyl] amino] -1- [ (3, 5-dibromo-4-hydroxyphenyl) methyl] -2-oxoethyl] -4- (1, 4-dihydro-2-oxo-3 (2H) -quinazolinyl) -1-piperidinecarboxamide; BIBN 4096BS; BIBN 4096. Grades: Highly Purified. CAS No. 204697-65-4. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Olcegepant hydrochloride | Olcegepant hydrochloride is the first potent and selective non-peptide antagonist of the calcitonin gene-related peptide 1 (CGRP1) receptor with 150-fold selective over the peptidic antagonist CGRP8-37 (IC50 = 0.03 nM, Ki = 14.4 pM for human CGRP). Synonyms: N-[(2R)-1-[[(2S)-6-amino-1-oxo-1-(4-pyridin-4-ylpiperazin-1-yl)hexan-2-yl]amino]-3-(3,5-dibromo-4-hydroxyphenyl)-1-oxopropan-2-yl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide;hydrochloride; Olcegepant (hydrochloride); Olcegepant hydrochloride. CAS No. 586368-06-1. Molecular formula: C38H47Br2N9O5.HCl. Mole weight: 906.11. | |
| Rat CGRP-(8-37) | CGRP 8-37 (rat) is a peptide antagonist for CGRP1 receptors. Synonyms: Calcitonin Gene-Related Peptide 8-37 (rat); 8-37-a-Calcitoningene-related peptide (human reduced), 25-L-aspartic acid, 35-L-glutamic acid-; Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asp-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Glu-Ala-Phe-NH2; CGRP 8-37 rat; L-valyl-L-threonyl-L-histidyl-L-arginyl-L-leucyl-L-alanyl-glycyl-L-leucyl-L-leucyl-L-seryl-L-arginyl-L-seryl-glycyl-glycyl-L-valyl-L-valyl-L-lysyl-L-alpha-aspartyl-L-asparagyl-L-phenylalanyl-L-valyl-L-prolyl-L-threonyl-L-asparagyl-L-valyl-glycyl-L-seryl-L-alpha-glutamyl-L-alanyl-L-phenylalaninamide. Grades: ≥95%. CAS No. 129121-73-9. Molecular formula: C138H224N42O41. Mole weight: 3127.51. | |
| Rimegepant | Rimegepant (BMS-927711) is a highly potent, oral calcitonin gene-related peptide ( CGRP ) receptor antagonist with a K i of 0.027 nM and an IC 50 of 0.14 nM for hCGRP receptor [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-927711; BHV-3000. CAS No. 1289023-67-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15498. | |
| SB 268262 | SB 268262 is a selective and non-peptide calcitonin gene-related peptide (CGRP1) receptor antagonist. SB 268262 inhibits [125I]CGRP binding and CGRP-activated adenylyl cyclase stimulation in SK-N-MC cell membranes (IC50 = 0.24 and 0.83 nM, respectively). Synonyms: SB 268262; SB-268262; SB268262; N-Methyl-N-(2-methylphenyl)-3-nitro-4-(2-thiazolylsulfinyl)-benzamide. Grades: ≥99% by HPLC. CAS No. 217438-17-0. Molecular formula: C18H15N3O4S2. Mole weight: 401.46. | |
| Telcagepant | Telcagepant is a calcitonin gene-related peptide(CGRP) receptor antagonist under development for the acute treatment and prevention of migraine. It is a highly potent, selective, and orally bioavailable antagonist of the human (K(I) = 0.77 nM) and rhesus (K(I) = 1.2 nM) CGRP receptors, which displays 1500-fold lower affinity for the canine and rat receptors as determined via (125)I-human CGRP competition binding assays in vitro. It displayed moderate clearance (14-20 ml min(-1) kg(-1)) in monkeys, while oral bioavailability was 6%. It was developed by Merck & Co. It was found to have equal potency to rizatriptan and zolmitriptan in two Phase III clinical trials in the acute treatment of migraine. But the company has now terminated development of the drug. Uses: Telcagepant is used to acute treatment and prevention of migraine. Synonyms: MK 0974; MK0974; MK-0974; N-[(3R,6S)-6-(2,3-Difluorophenyl)hexahydro-2-oxo-1-(2,2,2-trifluoroethyl)-1H-azepin-3-yl]-4-(2,3-dihydro-2-oxo-1H-imidazo[4,5-b]pyridin-1-yl)-1-piperidinecarboxamide;N-(6-(2,3-Difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)azepan-3-yl)-4-(2-oxo-2,3-dihydro-1H-imidazo(4,5-B)pyridin-1-yl)piperidine-1-carboxamide. Grades: 95%. CAS No. 781649-09-0. Molecular formula: C26H27F5N6O3. Mole weight: 566.53. | |
| Telcagepant | Telcagepant (MK-0974) is an orally active calcitonin gene-related peptide (CGRP) receptor antagonist with K i s of 0.77 nM and 1.2 nM for human and rhesus CGRP receptors, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-0974. CAS No. 781649-09-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-32709. | |
| (Tyr27)-α-CGRP (27-37) (canine, mouse, rat) | (Tyr27)-α-CGRP (27-37) (canine, mouse, rat) is an empirically synthesized and selectively constructed peptide, epitomizing a conspicuous fragment of Calcitonin Gene-Related Peptide (CGRP). Synonyms: [Tyr0] Calcitonin Gene Related Peptide (28-37), rat; H-Tyr-Val-Pro-Thr-Asn-Val-Gly-Ser-Glu-Ala-Phe-NH2; L-tyrosyl-L-valyl-L-prolyl-L-threonyl-L-asparagyl-L-valyl-glycyl-L-seryl-L-alpha-glutamyl-L-alanyl-L-phenylalaninamide. Grades: 95%. CAS No. 124501-79-7. Molecular formula: C54H79N13O17. Mole weight: 1182.28. | |
| Ubrogepant | Ubrogepant is and selective oral calcitonin gene-related peptide (CGRP) receptor antagonist originated by Merck & Co. In Sep 2016, Allergan initiated a phase III extension trial for Migraine in USA. Uses: Migraine. Synonyms: MK-1602; MK 1602; MK1602; Ubrogepant; (3'S)-1',2',5,7-Tetrahydro-N-[(3S,5S,6R)-6-methyl-2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)-3-piperidinyl]-2'-oxo-spiro[6H-cyclopenta[b]pyridine-6,3'-[3H]pyrrolo[2,3-b]pyridine]-3-carboxamide. Grades: 98%. CAS No. 1374248-77-7. Molecular formula: C29H26F3N5O3. Mole weight: 549.55. | |
| Ubrogepant | Ubrogepant (MK-1602) is an orally active and selective antagonist of calcitonin gene-related peptide receptor ( CGRP ). Ubrogepant has high affinity for CGRP receptors in human and rhesus monkeys, and can effectively block the cAMP response stimulated by α-CGRP. Ubrogepant can be used in the study of acute migraine [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-1602. CAS No. 1374248-77-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12366. | |
| Vazegepant | Vazegepant (Zavegepant) is an orally active calcitonin gene-related peptide CGRP receptor antagonist with potential for acute research in migraine, can be administered intranasally. CGRP is an important trigger in migraine pathophysiology [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Zavegepant; BHV-3500. CAS No. 1337918-83-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134992. | |
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