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| Product | Description | |
|---|---|---|
| Calcitonin gene-related peptide | Calcitonin gene-related peptide is a member of the calcitonin family of peptides consisting of calcitonin, amylin, adrenomedullin, adrenomedullin 2 (intermedin) and calcitonin - receptor - stimulating peptide. Synonyms: Calcitonin, pro-; CALCA protein, human; CALC1 protein, human; CGRP1 protein, human. CAS No. 83652-28-2. Molecular formula: C163H266N50O50S2. Mole weight: 3790.28. |  |
| Calcitonin gene-related peptide 1 (16-25) | Calcitonin gene-related peptide 1 (16-25) is a peptide derived from Calcitonin gene-related peptide 1. Calcitonin gene-related peptide 1 dilates a variety of vessels including the coronary, cerebral and systemic vasculature. It also elevates platelet cAMP. Synonyms: Alpha-type CGRP (16-25). | |
| Calcitonin gene-related peptide free acid | Calcitonin gene-related peptide (CGRP) free acid is the deamidated form of α-CGRP(human) (HY-P1071). Calcitonin gene-related peptide can be used to study the effect of C-terminal amidation on CGRP [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: CGRP free acid. CAS No. 83652-28-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P4058. |  |
| 1-L-Serine-3-L-asparagine-25-L-aspartic acid-35-L-glutamic acid-α-calcitonin gene-related peptide (human reduced) | It is a specific form of the neuropeptide α-CGRP, which is derived from the calcitonin gene. This peptide is a reduced form of human α-CGRP, featuring specific amino acid substitutions and modifications that influence its biological activity and structure. Synonyms: α-Calcitonin gene-related peptide (human reduced), 1-L-serine-3-L-asparagine-25-L-aspartic acid-35-L-glutamic acid-; Calcitonin gene related peptide rat; L-Seryl-L-cysteinyl-L-asparaginyl-L-threonyl-L-alanyl-L-threonyl-L-cysteinyl-L-valyl-L-threonyl-L-histidyl-L-arginyl-L-leucyl-L-alanylglycyl-L-leucyl-L-leucyl-L-seryl-L-arginyl-L-serylglycylglycyl-L-valyl-L-valyl-L-lysyl-L-α-aspartyl-L-asparaginyl-L-phenylalanyl-L-valyl-L-prolyl-L-threonyl-L-asparaginyl-L-valylglycyl-L-seryl-L-α-glutamyl-L-alanyl-L-phenylalaninamide; H-Ser-Cys-Asn-Thr-Ala-Thr-Cys-Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asp-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Glu-Ala-Phe-NH2. Grade: ≥95%. CAS No. 96827-03-1. Molecular formula: C162H264N50O52S2. Mole weight: 3808.31. | |
| 1,3-Dihydro-1-(4-piperidinyl)-2H-imidazo[4,5-b]pyridin-2-one Dihydrochloride | 1,3-Dihydro-1-(4-piperidinyl)-2H-imidazo[4,5-b]pyridin-2-one is an intermediate used to prepare (3R,6S)-3-amino-6-(2,3-difluorophenyl)azepan-2-one of Telcagepant (MK-0974) for use as a calcitonin gene-related peptide receptor antagonist treating migraine headaches. Group: Biochemicals. Grades: Highly Purified. CAS No. 781649-84-1. Pack Sizes: 100mg, 500mg. Molecular Formula: C11H16Cl2N4O. US Biological Life Sciences. |  Worldwide |
| 1-(tert-Butyloxycarbonyl)-3-Fluoro-4-aminopiperidine | 1-(tert-Butyloxycarbonyl)-3-Fluoro-4-aminopiperidine is a reactant in the preparation of pharmaceutical compounds which are antagonists of CGRP (Calcitonin gene-related peptide) receptors and useful in the treatment of migraine. Group: Biochemicals. Grades: Highly Purified. CAS No. 934536-10-4. Pack Sizes: 100mg, 500mg. Molecular Formula: C10H19FN2O2, Molecular Weight: 218.27. US Biological Life Sciences. | Worldwide |
| (2R)-2-Amino-3-(4-aminophenyl)propanoic Acid | (2R)-2-Amino-3-(4-aminophenyl)propanoic Acid is an amino acid that is used as a reactant in the development of human calcitonin gene-related peptide (CGRP) receptor antagonists for treatment of acute migraine. Group: Biochemicals. Grades: Highly Purified. CAS No. 102281-45-8. Pack Sizes: 100mg, 250mg. Molecular Formula: C9H12N2O2. US Biological Life Sciences. | Worldwide |
| Ac-Tyr-Arg-cetyl ester | Ac-Tyr-Arg-cetyl ester is an ingredient in anti-wrinkle cosmetics. It can inhibit the production of calcitonin gene-related peptide (CGRP), produce β-endorphins, and raise the threshold of skin sensitivity to heat. Synonyms: L-Arginine, N-acetyl-L-tyrosyl-, hexadecyl ester; Acetyl dipeptide-1 cetyl ester; Calmosensine; Calmosensine (cosmetic ingredient); Idealift; Acetyl tyrosylarginine cetyl ester; N-Acetyl dipeptide-1 cetyl ester. Grade: 98%. CAS No. 196604-48-5. Molecular formula: C33H57N5O5. Mole weight: 603.84. | |
| α-CGRP (human) | α-CGRP (human) is an endogenous calcitonin gene-related peptide receptor (CGRP) agonist. Synonyms: Calcitonin Gene Related Peptide; CGRP, human. CAS No. 90954-53-3. Molecular formula: C163H267N51O49S2. Mole weight: 3789.33. | |
| α-CGRP(human) | α-CGRP(human) (Calcitonin gene-related peptide) is a regulatory neuropeptide of 37 amino acids. α-CGRP(human) is widely distributed in the central and peripheral nervous system. α-CGRP(human) is a potent vasodilator and has inotropic and chronotropic effects [1] [2] [3]. Uses: Scientific research. Group: Peptides. Alternative Names: Calcitonin gene-related peptide. CAS No. 90954-53-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1071. | |
| α-CGRP (human) TFA | α-CGRP (human) is an endogenous calcitonin gene-related peptide receptor (CGRP) agonist. Synonyms: Calcitonin Gene Related Peptide (TFA); CGRP, human (TFA). Molecular formula: C163H267N51O49S2 (free base). Mole weight: 3789.33 (free base). | |
| α-CGRP (mouse, rat) | ?-CGRP (mouse, rat), a neuropeptide (calcitonin gene-related peptide (CGRP)) mainly expressed in neuromuscular junction, is a potent vasodilator. ?-CGRP (mouse, rat) can lead to a fall in blood pressure and an increase in heart rate by peripheral administration, also relax colonie smooth muscle. ?-CGRP (mouse, rat) has the potential in cardiovascular, pro-inflammatory, migraine and metabolic studies[1][2][3][4]. Uses: Scientific research. Group: Peptides. Alternative Names: CGRP (83-119), mouse, rat. CAS No. 83651-90-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P0203. | |
| β-CGRP, human | β-CGRP, human is a highly effective vasodilator. Synonyms: H-Ala-Cys-Asn-Thr-Ala-Thr-Cys-Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Met-Val-Lys-Ser-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Lys-Ala-Phe-NH2 (Disulfide bridge: Cys2-Cys7); Human β-CGRP; CGRP-II (Human); Calcitonin Gene Related Peptide II, human; α-Calcitonin gene-related peptide (human), 3-L-asparagine-22-L-methionine-25-L-serine-; β-Calcitonin gene-related peptide (human); L-Alanyl-L-cysteinyl-L-asparaginyl-L-threonyl-L-alanyl-L-threonyl-L-cysteinyl-L-valyl-L-threonyl-L-histidyl-L-arginyl-L-leucyl-L-alanylglycyl-L-leucyl-L-leucyl-L-seryl-L-arginyl-L-serylglycylglycyl-L-methionyl-L-valyl-L-lysyl-L-seryl-L-asparaginyl-L-phenylalanyl-L-valyl-L-prolyl-L-threonyl-L-asparaginyl-L-valylglycyl-L-seryl-L-lysyl-L-alanyl-L-phenylalaninamide cyclic (2→7)-disulfide; Human beta calcitonin gene-related peptide; Human calcitonin gene-related peptide 2; Human calcitonin gene-related peptide β; Human calcitonin gene-related peptide-II; Human calcitonin-related peptide II; Human β-calcitonin gene-related peptide. Grade: 95%. CAS No. 101462-82-2. Molecular formula: C162H267N51O48S3. Mole weight: 3793.35. | |
| BMS694153 | BMS694153 is a potent and selective calcitonin gene-related peptide(CGRP) receptor antagonist. It is related with the pathogenesis of migraine. Uses: Bms694153 is related with the pathogenesis of migraine. Synonyms: BMS-694153; BMS 694153; BMS694153; (R)-N-(1-([1,4'-bipiperidin]-1'-yl)-3-(7-methyl-1H-indazol-5-yl)-1-oxopropan-2-yl)-4-(8-fluoro-2-oxo-1,4-dihydroquinazolin-3(2H)-yl)piperidine-1-carboxamide; (R)-4-(8-Fluoro-2-oxo-1,2-dihydroquinazolin-3(4H)-yl)-N-(3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-(piperidin-1-yl)piperidin-1-yl)propan-2-yl)piperidine-1-carboxamide; 4-(8-Fluoro-2-oxo-1,4-dihydroquinazolin-3-yl)-N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]piperidine-1-carboxamide. Grade: >98 %. CAS No. 1050381-35-5. Molecular formula: C35H45FN8O3. Mole weight: 644.79. | |
| (±)-Boc-α-phosphonoglycine trimethyl ester | (±)-Boc-α-phosphonoglycine trimethyl ester is used as a reagent in the chemical synthesis of compounds such as Biphenomycin B, which is a potent antibiotic against Gram-neg., and imidazoles as potent calcitonin gene-related peptide (CGRP) antagonists. Synonyms: (±)-Trimethyl-Boc-α-phosphonoglycinate; (Dimethoxyphosphinyl)[[(1,1-dimethylethoxy)carbonyl]amino]acetic Acid Methyl Ester; 2-(Dimethoxyphosphinyl)-2-[[(1,1-dimethylethoxy)carbonyl]amino]acetic Acid Methyl Ester; Methyl 2-[(tert-butoxycarbonyl)amino]-2-(dimethoxyphosphoryl)acetate; (+/-)-Boc-alpha-phosphonoglycine trimethyl ester; N-Boc-2-Phosphonoglycine trimethyl ester; methyl 2-dimethoxyphosphoryl-2-[(2-methylpropan-2-yl)oxycarbonylamino]acetate; N-BUTOXYCARBONYL TRIMETHYLPHOSPHONOGLYCINE; Boc-GlyP(O)(OMe)2OMe; Boc-alpha-phosphonoglycine Trimethyl Ester. Grade: ≥ 98% (TLC). CAS No. 89524-98-1. Molecular formula: C10H20NO7P. Mole weight: 297.24. | |
| CGRP (rat) | α-CGRP (rat) is an endogenous neuropeptide displaying vasodilator, cardiovascular, pro-inflammatory and metabolic effects. Synonyms: Calcitonin Gene-Related Peptide (rat). Grade: >95%. CAS No. 83651-90-5. Molecular formula: C162H262N50O52S2. Mole weight: 3806.3. | |
| Eptinezumab | Eptinezumab is a humanized monoclonal antibody. Eptinezumab binds to calcitonin gene-related peptide (CGRP) and blocks its interaction with the receptor. Eptinezumab is used for the prevention of migraine in adults [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1644539-04-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99017. | |
| Eptinezumab | Eptinezumab is a humanized monoclonal antibody targeting calcitonin gene-related peptide (CGRP). Eptinezumab has been used for the preventive treatment of migraine in adults. Synonyms: Vyepti. CAS No. 1644539-04-7. | |
| Erenumab | Erenumab is a humanized monoclonal antibody targeting calcitonin gene-related peptide (CGRP). Erenumab has been used for the preventive treatment of migraines. Synonyms: Aimovig. CAS No. 1582205-90-0. | |
| Fremanezumab | Fremanezumab is a humanized monoclonal antibody targeting calcitonin gene-related peptide (CGRP). Fremanezumab has been investigated for the prevention of high-frequency episodic and chronic migraine. Synonyms: TEV-48125. CAS No. 1655501-53-3. | |
| Fremanezumab | Fremanezumab (TEV-48125) is a humanized IgG2a monoclonal antibody that selectively and potently binds to calcitonin gene-related peptide (CGRP). CGRP is a 37-amino acid neuropeptide involved in central and peripheral pathophysiological events of migraine. Fremanezumab has the potential for chronic migraine research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: TEV-48125. CAS No. 1655501-53-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99019. | |
| Galcanezumab | Galcanezumab is a humanized monoclonal antibody that selectively binds to calcitonin gene-related peptide (CGRP). Galcanezumab has the potential for the preventive treatment of chronic migraine. Synonyms: LY 2951742; LY2951742; LY-2951742. CAS No. 1578199-75-3. | |
| HCGRP-(8-37) | HCGRP-(8-37) is a human calcitonin gene-related peptide (hCGRP) fragment and also an antagonist of CGRP receptor. Uses: Scientific research. Group: Peptides. Alternative Names: Human ?-CGRP (8-37). CAS No. 119911-68-1. Pack Sizes: 500 ?g; 1 mg; 5 mg; 10 mg. Product ID: HY-P1014. | |
| HCGRP-(8-37) acetate | HCGRP-(8-37) acetate is the human calcitonin gene-related peptide (hCGRP) fragment and also an antagonist of CGRP1 receptors. Synonyms: H-Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asn-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Lys-Ala-Phe-NH2.CH3CO2H; L-valyl-L-threonyl-L-histidyl-L-arginyl-L-leucyl-L-alanyl-glycyl-L-leucyl-L-leucyl-L-seryl-L-arginyl-L-seryl-glycyl-glycyl-L-valyl-L-valyl-L-lysyl-L-asparagyl-L-asparagyl-L-phenylalanyl-L-valyl-L-prolyl-L-threonyl-L-asparagyl-L-valyl-glycyl-L-seryl-L-lysyl-L-alanyl-L-phenylalaninamide acetic acid; Human alpha-CGRP (8-37) acetate; 8-37-α-Calcitonin gene-related peptide (human) acetate; Human calcitonin gene-related peptide (8-37) acetate; Human CGRP(8-37) acetate; Human α-calcitonin gene-related peptide(8-37) acetate; Human α-CGRP (8-37) acetate. Grade: ≥95%. Molecular formula: C141H234N44O40. Mole weight: 3185.64. | |
| Olcegepant | Olcegepant (BIBN-4096) is a potent and selective non-peptide antagonist of the calcitonin gene-related peptide 1 (CGRP1) receptor with IC50 of 0.03 nM and Ki of 14.4 pM for human CGRP[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BIBN-4096; BIBN 4096BS. CAS No. 204697-65-4. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-10095. | |
| Olcegepant | Olcegepant is a potent and selective calcitonin gene-related peptide (CGRP) receptor antagonist. Olcegepant displays high affinity for human CGRP receptors and exhibits no significant affinity for 75 other receptors. Olcegepant may a be viable option for the treatment of acute migraines. Group: Biochemicals. Alternative Names: 1-[3,5-Dibromo-N-[[4-(1,4-dihydro-2-oxo-3(2H)-quinazolinyl)-1-piperidinyl]carbonyl]-D-tyrosyl-L-lysyl]-4-(4-pyridinyl)piperazine; N- [ (1R) -2- [ [ (1S) -5-Amino-1- [ [4- (4-pyridinyl) -1-piperazinyl] carbonyl] pentyl] amino] -1- [ (3, 5-dibromo-4-hydroxyphenyl) methyl] -2-oxoethyl] -4- (1, 4-dihydro-2-oxo-3 (2H) -quinazolinyl) -1-piperidinecarboxamide; BIBN 4096BS; BIBN 4096. Grades: Highly Purified. CAS No. 204697-65-4. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Rat CGRP-(8-37) | CGRP 8-37 (rat) is a peptide antagonist for CGRP1 receptors. Synonyms: Calcitonin Gene-Related Peptide 8-37 (rat); 8-37-a-Calcitoningene-related peptide (human reduced), 25-L-aspartic acid, 35-L-glutamic acid-; Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asp-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Glu-Ala-Phe-NH2; CGRP 8-37 rat; L-valyl-L-threonyl-L-histidyl-L-arginyl-L-leucyl-L-alanyl-glycyl-L-leucyl-L-leucyl-L-seryl-L-arginyl-L-seryl-glycyl-glycyl-L-valyl-L-valyl-L-lysyl-L-alpha-aspartyl-L-asparagyl-L-phenylalanyl-L-valyl-L-prolyl-L-threonyl-L-asparagyl-L-valyl-glycyl-L-seryl-L-alpha-glutamyl-L-alanyl-L-phenylalaninamide. Grade: ≥95%. CAS No. 129121-73-9. Molecular formula: C138H224N42O41. Mole weight: 3127.51. | |
| Rimegepant | Rimegepant (BMS-927711) is a highly potent, oral calcitonin gene-related peptide ( CGRP ) receptor antagonist with a K i of 0.027 nM and an IC 50 of 0.14 nM for hCGRP receptor [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-927711; BHV-3000. CAS No. 1289023-67-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15498. | |
| Telcagepant | Telcagepant (MK-0974) is an orally active calcitonin gene-related peptide (CGRP) receptor antagonist with K i s of 0.77 nM and 1.2 nM for human and rhesus CGRP receptors, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-0974. CAS No. 781649-09-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-32709. | |
| (Tyr27)-α-CGRP (27-37) (canine, mouse, rat) | (Tyr27)-α-CGRP (27-37) (canine, mouse, rat) is an empirically synthesized and selectively constructed peptide, epitomizing a conspicuous fragment of Calcitonin Gene-Related Peptide (CGRP). Synonyms: [Tyr0] Calcitonin Gene Related Peptide (28-37), rat; H-Tyr-Val-Pro-Thr-Asn-Val-Gly-Ser-Glu-Ala-Phe-NH2; L-tyrosyl-L-valyl-L-prolyl-L-threonyl-L-asparagyl-L-valyl-glycyl-L-seryl-L-alpha-glutamyl-L-alanyl-L-phenylalaninamide. Grade: 95%. CAS No. 124501-79-7. Molecular formula: C54H79N13O17. Mole weight: 1182.28. | |
| Ubrogepant | Ubrogepant (MK-1602) is an orally active and selective antagonist of calcitonin gene-related peptide receptor ( CGRP ). Ubrogepant has high affinity for CGRP receptors in human and rhesus monkeys, and can effectively block the cAMP response stimulated by α-CGRP. Ubrogepant can be used in the study of acute migraine [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-1602. CAS No. 1374248-77-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12366. | |
| Vazegepant | Vazegepant (Zavegepant) is an orally active calcitonin gene-related peptide CGRP receptor antagonist with potential for acute research in migraine, can be administered intranasally. CGRP is an important trigger in migraine pathophysiology [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Zavegepant; BHV-3500. CAS No. 1337918-83-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134992. | |
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