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Commonly known as EDAC, EDC or EDCI, this carbodiimide HCl salt is used as a coupling reagent in the synthesis of amides and carboxylic esters. EDAC is highly soluble in water and in most organic solvents, it can be employed in liquid and solid-phase and synthesis. The major advantage of EDCI over other carbodiimides such as DCC and DIC is the ease of purification of the product from the water-soluble urea by-product by washing the crude mixture with water or mild acid and extracting in the organic phase. The main applications of EDAC are in peptide synthesis, Steglich esterification reactions in presence of catalytic DMAP, immunoconjugate synthesis, synthesis of sulfo-NHS esters and coupling of biomolecules onto solid supports. Group: Biochemicals. Alternative Names: EDC.HCl; EDAC. HCl; Water Soluble Carbodiimide; N-Ethyl-N'- (3-dimethylaminopropyl) carbodiimide HCl; 1-Ethyl-3- (3-dimethylaminopropyl) carbodiimide HCl. Grades: Highly Purified. CAS No. 25952-53-8. Pack Sizes: 25g, 50g, 100g, 250g, 500g. Molecular Formula: C8H17N3·HCl, Molecular Weight: 191.7. US Biological Life Sciences.
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride is a carbodiimide reagent that can form nucleic acid and compounds with amide bonds. 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride accelerates the formation reaction of esters, amides, and peptides, as a condensing and dehydrating agent, which are often used for polynucleotide synthesis, anhydroxydation, lactonization and esterification [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 25952-53-8. Pack Sizes: 5 g; 10 g. Product ID: HY-D0178.
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide methiodide is a water soluble carbodiimide used as an amide coupling reagent and cross-linking agent. 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide methiodide is effective in amide coupling where either the amine or the carboxylic acid is immobilised onto a polymeric solid support, such as core-shell structured nanoaggregates including nanospheres and nanorods. 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide methiodide can be also employed in the binding formation of DNA with N-acylurea derivatives of proteins, such as albumin and transferrin. Group: Biochemicals. Alternative Names: EDC methiodide; EDAC MeI. Grades: Highly Purified. CAS No. 22572-40-3. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C8H17N3·CH3I, Molecular Weight: 297.18. US Biological Life Sciences.
1-cyclohexyl-3-(2-(4-morpholinyl)ethyl)carbodiimide is a carbodiimide having cyclcohexyl and 2-(4-morpholinyl)ethyl as the two N-substituents. It has a role as a cross-linking reagent. It is a carbodiimide and a member of morpholines. Synonyms: 1-Cmec; CMCT; N-cyclohexyl-N'-(2-(4-morpholinyl)ethyl)carbodiimide; cyclohexyl-3-(2-morpholinoethyl)carbodiimide; cyclohexyl-(2-morpholino-ethyl)-carbodiimide; cyclohexyl-(2-morpholin-4-yl-ethyl)-carbodiimide; N-cyclohexyl-N-(2-morpholinoethyl)methanediimine; 1-cyclohexyl-3-(2-morpholino-ethyl)-carbodiimide; N'-cyclohexyl-N-(2-morpholin-4-ylethyl)methanediimine; Cyclohexyl-(2-morpholino-aethyl)-carbodiimide. Grades: ≥ 95% (GC). CAS No. 15580-20-8. Molecular formula: C13H23N3O. Mole weight: 237.34.
It is being used for the synthesis of amides. EDC HCl is also used as a coupling agent in the preparation of esters from carboxylic acids using dimethylaminopyridine as the catalyst. It is water-soluble carbodiimide, widely used for peptide coupling. Synonyms: EDC.HCL; 1-Ethyl-3-(3-dimethyllaminopropyl)carbodiimide hydrochloride; EDC hydrochloride; EDCI; 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride; 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide Hydrochloride [Coupling Agent; EDAP; 1-Ethyl-3-(3-dimethyllaminopropyl)carbodiimide hydrochloride; edac hcl; wsc hcl; N1-((Ethylimino)methylene)-N3,N3-dimethylpropane-1,3-diamine hydrochloride. Grades: 98%. CAS No. 25952-53-8. Molecular formula: C8H17N3·HCl. Mole weight: 191.70.
Bis- (2, 6-diisopropylphenyl) carbodiimide
Bis- (2, 6-diisopropylphenyl) carbodiimide. Group: Biochemicals. Grades: Highly Purified. CAS No. 2162-74-5. Pack Sizes: 2g, 5g, 10g, 25g, 50g. Molecular Formula: C25H34N2. US Biological Life Sciences.
N-Cyclohexyl-N'- (2-morpholinoethyl) carbodiimide methyl-p-toluenesulfonate ≥96% (NMR). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
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N, N-Dicyclohexyl carbodiimide
N, N'-Dicyclohexyl carbodiimide is a carbodiimide used to couple amino acids during peptide synthesis. N, N'-Dicyclohexyl carbodiimide is used as a dehydrating agent for the preparation of amides, ketones, nitriles as well as in the inversion and esterification of secondary alcohols. Group: Biochemicals. Alternative Names: 1, 3-Dicyclohexyl carbodiimide ; Bis (cyclohexyl) carbodiimide; DCC; DCCD; DCCI; Dicyclohexyl carbodiimide ; N, N-Methanetetraylbis [cyclohexanamine]; NSC 30022; NSC 53373; NSC 57182. Grades: Highly Purified. CAS No. 538-75-0. Pack Sizes: 10g. US Biological Life Sciences.
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N, N'-Dicyclohexyl carbodiimide Pentachlorophenol Complex (Kovacs Complex)
Useful reagent for preparing amino acid pentachlorophenol active esters. Group: Biochemicals. Alternative Names: Kovacs Complex. Grades: Highly Purified. Pack Sizes: 10g. US Biological Life Sciences.
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N, N'-Diisopropyl carbodiimide 99+%
N, N'-Diisopropyl carbodiimide 99+%. Group: Biochemicals. Grades: Reagent Grade. CAS No. 693-13-0. Pack Sizes: 25g, 100g, 500g, 1Kg. US Biological Life Sciences.
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1-Ethyl-2-methyl-3-phospholene 1-Oxide
1-Ethyl-2-methyl-3-phospholene 1-Oxide is an isomer of 1-Ethyl-3-methyl-3-phospholene 1-Oxide (E924875), a phospholine oxide catalyst used to convert isocyanates to carbodiimides. Group: Biochemicals. Grades: Highly Purified. CAS No. 61441-50-7. Pack Sizes: 1g, 2.5g. Molecular Formula: C7H13OP, Molecular Weight: 144.15. US Biological Life Sciences.
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1-Ethyl-3-methyl-3-phospholene 1-Oxide
1-Ethyl-3-methyl-3-phospholene 1-Oxide is a phospholine oxide catalyst used to convert isocyanates to carbodiimides. Group: Biochemicals. Grades: Highly Purified. CAS No. 7529-24-0. Pack Sizes: 1g, 2.5g. Molecular Formula: C7H13OP, Molecular Weight: 144.15. US Biological Life Sciences.
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3-(Ethylthio)-butanoic Acid
3-(Ethylthio)-butanoic Acid is a reagent in the synthesis of amide using polyer-bound EDC (1-ethyl-3- (3-dimethylaminopropyl) carbodiimide) as coupling reagent. Group: Biochemicals. Grades: Highly Purified. CAS No. 89534-40-7. Pack Sizes: 100mg, 1g. Molecular Formula: C6H12O2S, Molecular Weight: 148.22. US Biological Life Sciences.
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(5)6-Carboxytetramethylrhodamine
(5)6-Carboxytetramethylrhodamine contains a carboxylic acid that can be used to react with primary amines via carbodiimide activation of the carboxylic acid; bright, orange-fluorescent dye produces conjugates with absorption/emission maxima of ~555/580 nm [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 117557-83-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-D0934.
Carboxylic Acid-Doxorubicin Liposome (PEGylated)
This formulation is Doxorubicin Liposome (PEGylated) with the carboxyl group, which can be activated by EDC (1-ethyl-3-[3-dimethylaminopropyl] carbodiimide) and react with sulfo-NHS (N-hydroxysulfosuccinimide) to produce a significantly more stable and more soluble active intermediate (NHS ester). The intermediate can covalently conjugate to the amine group on the proteins, peptides or antibodies through displacement of sulfo-NHS group by amine. Group: Drug-loaded liposome. Categories: liposomes, niosomes, ethosomes, and transfersomes.
DIC
Advantage over N,N-Dicyclohexylcarbodiimide in solid phase peptide syntheses that the urea by-product is more soluble in organic solvents and hence more readily separated from the polymer support. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: N,N-Diisopropylcarbodiimide. CAS No. 693-13-0.
Luxembourg Bio Technologies
EDC·HCl
EDC·HCl, usually known as water soluble carbodiimide, is a versatile modern coupling agent. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: 1-Ethyl-3-(3-Dimethyllaminopropyl) Carbodiimide hydrochloride. CAS No. 25952-53-8.
Luxembourg Bio Technologies
Ethyl cyanoglyoxylate-2-oxime
Ethyl cyanoglyoxylate-2-oxime can be used as an additive for the carbodiimide-mediated amide bond formation during established peptide synthesis method. Synonyms: OxymaPure; Ethyl 2-cyano-2-(hydroxyimino)acetate; Ethyl (hydroxyimino)cyanoacetate; Cyano(hydroxyimino)-acetic Acid Ethyl Ester; 2-Cyano-2-(hydroxyimino)acetic Acid Ethyl Ester; Ethyl 2-(Hydroxyimino)cyanoacetate; Ethyl 2-Cyano-2-(hydroxyimino)acetate; Ethyl 2-Cyano-2-(hydroxyimino)ethanoate; Ethyl 2-Cyano-2-oximinoacetate; Ethyl 2-Hydroxyimino-2-cyanoacetate; Ethyl Cyano(hydroxyimino)acetate; Ethyl Cyanoglyoxylate Oxime; Ethyl Cyanoglyoxylate-2-oxime; Ethyl α-Cyano-α-oximinoacetate; NSC 137667; NSC 41021; NSC 42116; Oxyma Pure; (E)-Ethyl 2-Cyano-2-(hydroxyimino)acetate. Grades: ≥ 97 %. CAS No. 3849-21-6. Molecular formula: C5H6N2O3. Mole weight: 142.11.
N-Hydroxysuccinimide
Additive used in the carbodiimide method for improved amidations and peptide couplings. Synonyms: 1-Hydroxy-2,5-pyrrolidinedione; N-Hydroxy-2,5-dioxopyrrolidine; 1-Hydroxysuccinimide; NSC 74335; NHS; N-hydroxysuccinimid; UNII-MJE3791M4T; CCRIS 2604; N-hydroxy-succinimide; EINECS 228-001-3. Grades: 98%. CAS No. 6066-82-6. Molecular formula: C4H5NO3. Mole weight: 115.09.
Additive used in the carbodiimide method for improved amidations and peptide couplings. Group: Biochemicals. Alternative Names: 1-Hydroxy-2,5-pyrrolidinedione. Grades: Highly Purified. Pack Sizes: 100g. US Biological Life Sciences.
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N-Hydroxysuccinimide (NHS)
Reagent for preparation of active esters of amino acids. Used in the carbodiimide method for improved amidations and peptide couplings. Group: Biochemicals. Alternative Names: HOSu; 1-Hydroxy-2,5-pyrrolidinedione; N-Hydroxy-2,5-dioxopyrrolidine; 1-Hydroxysuccinimide; NSC 74335; NHS. Grades: Highly Purified. CAS No. 6066-82-6. Pack Sizes: 25g, 100g, 250g, 1Kg, 5Kg. Molecular Formula: C?H?NO?, Molecular Weight: 115.1. US Biological Life Sciences.
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N,N'-Methanetetrayldi-O-toluidine
Heterocyclic Organic Compound. Alternative Names: DI-O-TOLYLCARBODIIMIDE; n, n'-methanetetraylbis[2-methyl-benzenamin; N, N'-methanetetrayldi-o-toluidine; N, N'-Bis(2-methylphenyl)methanediimine; N, N'-Di(2-methylphenyl)carbodiimide; Benzenamine, N,N'-methanetetraylbis(2-methyl-;Bis(o-tolylcarbodiimide);Einecs 2. CAS No. 1215-57-2. Molecular formula: C15H14N2. Mole weight: 222.29. Catalog: ACM1215572.
Orotidine 5'-Monophosphate Trisodium Salt
Orotidine 5'-Monophosphate Trisodium Salt is synthesized from the reaction of silver salt with MeI and phosphorylated with the cyanoethyl phosphate-dicyclohexyl carbodiimide reagent. Group: Biochemicals. Grades: Highly Purified. CAS No. 68244-58-6. Pack Sizes: 1mg. Molecular Formula: C10H10N2Na3O11P, Molecular Weight: 434.14. US Biological Life Sciences.
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OxymaPure®
Used with carbodiimide coupling methodology, for amide bond formation. remarkable capacity to suppress racemization and an impressive coupling efficiency in both automated and manual synthesis. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: Ethyl (hydroxyimino) cyanoacetate, " 2-cyano-2-(hydroxyimino)acetate". CAS No. 3849-21-6.
Luxembourg Bio Technologies
Succinyl-Doxorubicin Liposome (PEGylated)
This formulation is Doxorubicin Liposome (PEGylated) with the carboxyl group, which can be activated by EDC (1-ethyl-3-[3-dimethylaminopropyl] carbodiimide) and react with sulfo-NHS (N-hydroxysulfosuccinimide) to produce a significantly more stable and more soluble active intermediate (NHS ester). The intermediate can covalently conjugate to the amine group on the proteins, peptides or antibodies through displacement of sulfo-NHS group by amine. Group: Drug-loaded liposome. Categories: liposomes, niosomes, ethosomes, and transfersomes.