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Carbonicanhydrase, Bovine erythrocytes (EC 4.2.1.1) is ubiquitous zinc-containing metalloenzyme present in prokaryotes and eukaryotes. Carbonicanhydrase can catalyze reversible conversion of carbon dioxide to bicarbonate and protons. Carbonicanhydrase can be used for the research of cancer, glaucoma, obesity and epilepsy [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EC 4.2.1.1. CAS No. 9001-03-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1775.
Carbonicanhydrase from E. coli, recombinant
The carbonicanhydrases (or carbonate dehydratases) form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons (or vice versa), a reversible reaction that occurs relatively slowly in the absence of a catalyst. The active site of most carbonicanhydrases contains a zinc ion; they are therefore classified as metalloenzymes. Group: Enzymes. Synonyms: Carbonate dehydratase; CAN; yadF. Enzyme Commission Number: EC 4.2.1.1. Purity: > 95% by SDS-PAGE. CarbonicAnhydrase. Mole weight: This protein is fused with 6x His tag at N terminus and the protein has a calculated MW of 27 kDa (240aa). Activity: >1,000 pmol/min/ug. Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -70°C. Avoid repeated freezing and thawing cycles. Form: Liquid. Source: E. coli. Species: E. coli. carbonicanhydrases; carbonate dehydratases; EC 4.2.1.1; anhydrase; carbonate anhydrase; carbonic acid anhydrase; carboxyanhydrase; carbonicanhydrase A; carbonate hydro-lyase; CA; CAN; yadF. Cat No: NATE-1669.
CarbonicAnhydrase II from Bovine, Recombinant
The carbonicanhydrases (or carbonate dehydratases) form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons (or vice versa), a reversible reaction that occurs relatively slowly in the absence of a catalyst. The active site of most carbonicanhydrases contains a zinc ion; they are therefore classified as metalloenzymes. Carbonicanhydrase is a zinc-containing enzyme that catalyzes the reversible conversion of carbon dioxide to bicarbonate. one of its main physiological roles is to maintain the acid-base balance in blood and other tissues. lack of carbonicanhydrase results in carbonicanhydrase type ii defi...ns: Carbonicanhydrase is used to create carbon dioxide capture systems and to research various purification techniques. carbonicanhydrase is also used to study acid-base regulation in fish and carbonicanhydrase type ii deficiency syndrome. bovine carbonicanhydrase ii (ca II), has been widely used as a model protein in the investigation of the protein folding process. Group: Enzymes. Synonyms: carbonicanhydrases; carbonate dehydratases; EC 4.2.1.1; anhydrase; carbonate anhydrase; carbonic acid anhydrase; carboxyanhydrase; carbonicanhydrase A; carbonate hydro-lyase. Enzyme Commission Number: EC 4.2.1.1. CAS No. 9001-03-0. Purity: >90% by SDS-PAGE. Carbonic Anhydras
CarbonicAnhydrase II from Human, Recombinant
Carbonicanhydrase is a zinc metalloenzyme that has a molecular weight of approximately 30 kDa Da. The enzyme catalyzes the hydRation of carbon dioxide to carbonic acid. It is involved in vital processes such as pH and CO2 homeostasis, transport of bicarbonate and CO2, biosynthetic reactions, bone resorption, calcification, and tumorigenicity. Therefore, this enzyme is an important target for inhibitors with clinical applications in various pathologies such as glaucoma, epilepsy and Parkinsons disease. Applications: Human carbonicanhydrase isozyme ii has been used to assess its gene fusion abilities for efficient expression and recovery of recombinant proteins. human ...viduals. the enzyme has also been used in the study of natural phenolic inhibitors of ca ii. Group: Enzymes. Synonyms: CarbonicAnhydrase II; carbonate dehydRatase; carbonicanhydrase; anhydrase; carbonate anhydrase; carbonic acid anhydrase; carboxyanhydrase; carbonicanhydrase A; carbonate hydro-lyase; EC 4.2.1.1; CA-II; CA2; CarbonicAnhydrase 2. Enzyme Commission Number: EC 4.2.1.1. CAS No. 9001-03-0. CarbonicAnhydrase. Activity: > 80%, > 3 ,000 W-A units/mg protein. Form: powder. Source: E. coli. Species: Human. CarbonicAnhydrase II; carbonate dehydRatase; carbonicanhydrase; anhydrase; carbonate anhydrase; carbonic acid anhydrase; carboxyanhydrase; carbonic anhyd
Carbonicanhydrase inhibitor 2
Carbonicanhydrase inhibitor 1 (compound 7c) is a carbonicanhydrase II inhibitor. Carbonicanhydrase inhibitor 3 reduces the intraocular pressure in glaucomatous rabbits [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2758231-43-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-142849.
Carbonicanhydrase (isoenzyme)
Carbonicanhydrase isoenzyme is the isoenzyme of Carbonicanhydrase (HY-P1775). Carbonicanhydrase isoenzyme is ubiquitous zinc-containing metalloenzyme present in prokaryotes and eukaryotes. Carbonicanhydrase isoenzyme catalyzes reversible conversion of carbon dioxide to bicarbonate and protons, and can be used for the research of cancer, glaucoma, obesity and epilepsy [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 9001-03-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P1775A.
A cell permeable benzenesulfonamide CarbonicAnhydrase (CA) inhibitor that is selective for human hCA IX and hCA XII (Ki = 0.9nM and 5.7nM, respectively) against two other physiologically relevant hCA isoforms (Ki = 23.4nM and 15nM for hCA I and hCA II, respectively), as compared with another CA inhibitor AAZ (Ki = 250nM, 12nM, 25nM, and 5.7nM for hCA I, hCA II, hCA IX, and hCA XII, respectively). It is shown to effectively inhibit the formation of metastases by 4T1 breast cancer cells in a mouse model dose-dependently at pharmacologic concentrations of 15-45mg/kg. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
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CarbonicAnhydrase IX/XII Inhibitor II, U-104 (CAIX Inhibitor II)
A cell permeable ureido-sulfonamide CarbonicAnhydrase (CA) inhibitor that is selective for human hCA IX and hCA XII (KiEnM and 4.5nM, respectively) against two other physiologically relevant hCA isoforms (KiP80nM and 9640nM for hCA I and hCA II, respectively). It elicits anti-tumor growth effects dose-dependently from 19 to 38mg/kg in a mouse tumor growth model implanted with MDA-MB-231 LM2-4Luc+ cells, and demonstrates metastasis inhibition in a mouse metastasis model injected with 4T1 cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Control for 139560. Group: Molecular Biology. Pack Sizes: 15ul. US Biological Life Sciences.
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Native Bovine CarbonicAnhydrase
The carbonicanhydrases (or carbonate dehydratases) form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons (or vice versa), a reversible reaction that occurs relatively slowly in the absence of a catalyst. The active site of most carbonicanhydrases contains a zinc ion; they are therefore classified as metalloenzymes. It was from bovine erythrocytes. a dialyzed, lyophilized powder. Applications: Co2 determination in blood; elimination of co2 in reagents for acidity testing; carboxy group transfers; reduction reactions. Group: Enzymes. Synonyms: carbonicanhydrases; carbonate dehydratases; EC 4.2.1.1; anhydrase; carbonate anhydrase; carbonic acid anhydrase; carboxyanhydrase; carbonicanhydrase A; carbonate hydro-lyase. Enzyme Commission Number: EC 4.2.1.1. CAS No. 9001-03-0. CarbonicAnhydrase. Mole weight: 29.0 kDa (Theoretical) 30 kDa (Lindskog et al. 1971). Activity: > 3,000 units per mg dry weight. Storage: 2-8°C. Form: lyophilized powder. Source: Bovine Erythrocytes. Species: Bovine. carbonicanhydrases; carbonate dehydratases; EC 4.2.1.1; anhydrase; carbonate anhydrase; carbonic acid anhydrase; carboxyanhydrase; carbonicanhydrase A; carbonate hydro-lyase. Cat No: NATE-0101.
Native Human CarbonicAnhydrase
Carbonicanhydrase (carbonate dehydratase) catalyzes the following reaction: CO2 + H2O ------> H2CO3 The enzyme is widespread in nature. In animals it plays an important role in respiration by facilitating the transport of carbon dioxide. In plants, carbonicanhydrases are involved in the photosynthetic fixation of CO2.Mammalian erythrocytes contain two distinct forms of carbonicanhydrase distinguished by differences in their catalytic activities. The enzyme requires zinc for its activity and it has a molecular weight of 30,000. Group: Enzymes. Synonyms: carbonicanhydrases; carbonate dehydratases; EC 4.2.1.1; anhydrase; carbonate anhydrase; carbonic acid anhydrase; carboxyanhydrase; carbonicanhydrase A; carbonate hydro-lyase. Enzyme Commission Number: EC 4.2.1.1. CAS No. 9001-03-0. CarbonicAnhydrase. Activity: 2000 U/mg protein. Storage: Store at -20° C. Form: Freeze-dried powder. Source: Human Liver. Species: Human. carbonicanhydrases; carbonate dehydratases; EC 4.2.1.1; anhydrase; carbonate anhydrase; carbonic acid anhydrase; carboxyanhydrase; carbonicanhydrase A; carbonate hydro-lyase. Cat No: NATE-1678.
Native Human CarbonicAnhydrase I
Carbonicanhydrase is a zinc metalloenzyme that has a molecular weight of approximately 30 kDa Da. The enzyme catalyzes the hydRation of carbon dioxide to carbonic acid. It is involved in vital processes such as pH and CO2 homeostasis, transport of bicarbonate and CO2, biosynthetic reactions, bone resorption, calcification, and tumorigenicity. Therefore, this enzyme is an important target for inhibitors with clinical applications in various pathologies such as glaucoma, epilepsy and Parkinsons disease. Applications: Carbonicanhydrase from human erythrocytes (hca) has been used to study the molten-globule state of carbonicanhydrase (ca). chaperone-like α-crystallin bi...on-small cell lung cancer. Group: Enzymes. Synonyms: CarbonicAnhydrase I; carbonate dehydRatase; carbonicanhydrase; anhydrase; carbonate anhydrase; carbonic acid anhydrase; carboxyanhydrase; carbonicanhydrase A; carbonate hydro-lyase; EC 4.2.1.1; 9001-03-0; CA-I; CA1. Enzyme Commission Number: EC 4.2.1.1. CAS No. 9001-03-0. CarbonicAnhydrase. Activity: 100-500 W-A units/mg protein. Form: powder. Source: Human erythrocytes. Species: Human. CarbonicAnhydrase I; carbonate dehydRatase; carbonicanhydrase; anhydrase; carbonate anhydrase; carbonic acid anhydrase; carboxyanhydrase; carbonicanhydrase A; carbonate hydro-lyase; EC 4.2.1.1; 9001-03-0; CA-I; CA1. Cat No: NATE-0097.
1-(2-(Benzylthio)-5-chlorothiophen-3-yl)ethanone
Reagent used in the preparation of carbonicanhydrase inhibitors. Group: Biochemicals. Alternative Names: 1-[5-Chloro-2-[(phenylmethyl)thio]-3-thienyl]ethanone. Grades: Highly Purified. CAS No. 160982-09-2. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
1-(2-Sulfamidoethyl)-2-methyl-5-nitroimidazole
1-(2-Sulfamidoethyl)-2-methyl-5-nitroimidazole is a hypoxia-targeting carbonicanhydrase IX inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1383370-92-0. Pack Sizes: 100mg, 1g. Molecular Formula: C6H11N5O4S, Molecular Weight: 249.25. US Biological Life Sciences.
Worldwide
1,3-Dimethyluracil
1,3-Dimethyluracil is a pyrimidone derives from a uracil. 1,3-Dimethyluracil found occasionally in human urine. 1,3-Dimethyluracil shows inhibition activity against hCA I and hCA II (human carbonicanhydrase) with K i of 316.2 μM and 166.4 μM, respectively [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 874-14-6. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-W008343.
1-Amino-3-Hydroxybenzene
1-Amino-3-Hydroxybenzene is used in the preparation of inhibitors of mammalian carbonicanhydrase isoforms. Also used in the preparation of quinoline tethered fluorescent carbon dots for regulated anticancer discovery. Group: Biochemicals. Grades: Highly Purified. CAS No. 591-27-5. Pack Sizes: 10g, 50g. Molecular Formula: C6H7NO. US Biological Life Sciences.
Worldwide
2,3-Difluorobenzoic Acid
2,3-Difluorobenzoic acid is the difluorinated analogue of Benzoic acid (B203900). 2,3-Difluorobenzoic acid is a useful synthetic intermediate and is used as a starting material to synthesize thioether benzenesulfonamide inhibitors of carbonicanhydrases II and IV. Group: Biochemicals. Grades: Highly Purified. CAS No. 4519-39-5. Pack Sizes: 2.5g, 10 g. Molecular Formula: C7H4F2O2, Molecular Weight: 158.1. US Biological Life Sciences.
An impurity of Brinzolamide, a potent carbonicanhydrase inhibitor used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension. Synonyms: 2-(3-METHOXYPROPYL)-2H-THIENO[3,2-E][1,2]THIAZINE-6-SULFONAMIDE 1,1-DIOXIDE; 2-(3-methoxypropyl)-1,1-dioxothieno[3,2-e]thiazine-6-sulfonamide; B0464-284943; 2-(3-METHOXYPROPYL)-2H-THIENO[3,2-E][1,2]THIAZINE-6-SULFONAMIDE1,1-DIOXIDE. CAS No. 171273-35-1. Molecular formula: C10H14N2O5S3. Mole weight: 338.42.
2,4-Disulfamyl-5-trifluoromethylaniline
2,4-Disulfamyl-5-trifluoromethylaniline is a carbonicanhydrase inhibitor, used as a potential anti-tumor and antiglaucoma drug. Metabolite of hydroflumethazide, a diuretic. Group: Biochemicals. Grades: Highly Purified. CAS No. 654-62-6. Pack Sizes: 1g, 5g. Molecular Formula: C7H8F3N3O4S2. US Biological Life Sciences.
Worldwide
2-Aminobenzenesulfonamide
2-Aminobenzenesulfonamide is a potent inhibitor of carbonicanhydrase B. Synonyms: 2-aminobenzenesulfonamide. Grades: 98 %. CAS No. 3306-62-5. Molecular formula: C6H8N2O2S. Mole weight: 172.20.
2-Desaminosulfonyl 3-Aminosulfonyl Dorzolamide
2-Desaminosulfonyl 3-Aminosulfonyl Dorzolamide is a useful synthetic compound. Also, it is derived from (4R,6S)-5,6-Dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-4-ol 7,7-Dioxide (T344510), which is an analog of topically-active carbonicanhydrase inhibitor MK-507, commonly known Dorzolamide (D535100). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2mg. Molecular Formula: C10H16N2O4S3. US Biological Life Sciences.
2-Desaminosulfonyl 3-Aminosulfonyl N-Acetyl Dorzolamide is an intermediate in the synthesis of 2-Desaminosulfonyl 3-Aminosulfonyl Dorzolamide (D288235), which is derived from (4R,6S)-5,6-Dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-4-ol 7,7-Dioxide (T344510), which is an analog of topically-active carbonicanhydrase inhibitor MK-507, commonly known Dorzolamide (D535100). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C12H18N2O5S3. US Biological Life Sciences.
Worldwide
2-Hydroxyethanesulfonic Acid
2-Hydroxyethanesulfonic Acid is a reactant in the synthesis of 4-substituted-2, 3, 5, 6-tetrafluorobene zene sulfonamides as inhibitors of carbonicanhydrases I, II, VII, XII, and XIII. Group: Biochemicals. Grades: Highly Purified. CAS No. 107-36-8. Pack Sizes: 1g, 10g. Molecular Formula: C2H6O4S. US Biological Life Sciences.
Worldwide
2-Methyl-5-nitrobenzenesulfonamide
2-Methyl-5-nitrobenzenesulfonamide (CAS# 6269-91-6) is a chemical reagent in the synthesis of good inhibitors of cancer-related carbonicanhydrase. Also used in the synthesis of novel deacetylase inhibitors used in anti-tumor therapy. Synonyms: 2-methyl-5-nitrobenzenesulfonamide; 2-methyl-5-nitrobenzenesulfonamide. Grades: 98 %. CAS No. 6269-91-6. Molecular formula: C7H8N2O4S. Mole weight: 216.21.
2-Methyl-5-nitro Benzene sulfonamide
2-Methyl-5-nitro Benzene sulfonamide is a chemical reagent in the synthesis of good inhibitors of cancer-related carbonicanhydrase. Also used in the synthesis of novel deacetylase inhibitors used in anti-tumor therapy. Group: Biochemicals. Grades: Highly Purified. CAS No. 6269-91-6. Pack Sizes: 1g, 5g. Molecular Formula: C7H8N2O4S, Molecular Weight: 216.21. US Biological Life Sciences.
Worldwide
2-Nitro-benzenesulfonamide
2-Nitro-benzenesulfonamide is a carbonicanhydrase inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 5455-59-4. Pack Sizes: 1g, 5g. Molecular Formula: C6H6N2O4S, Molecular Weight: 202.19. US Biological Life Sciences.
Worldwide
3-Acetyl-5-chloro-2-thiophenesulfonamide
3-Acetyl-5-chloro-2-thiophenesulfonamide is a reactant used in the preparation of heteroaryl chalcones as potent antimicrobial agents and Brinzolamide (B677600), a topical carbonicanhydrase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 160982-10-5. Pack Sizes: 250mg. US Biological Life Sciences.
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4-Acetylphenylboronic acid
4-Acetylphenylboronic acid is a potent inhibitor of carbonicanhydrases II( CA II ), with IC 50 s of 246 μM and 281.40 μM for bovine CA II ( bCA II ) and human CA II ( hCA II ), respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 149104-90-5. Pack Sizes: 10 g. Product ID: HY-32933.
4-Desethylamino 4-oxobrinzolamide
4-Desethylamino 4-oxobrinzolamide is an impurity of Brinzolamide (B677600), a carbonicanhydrase inhibitor and a antiglaucoma agent. Group: Biochemicals. Alternative Names: 3,4-Dihydro-2-(3-methoxypropyl)-4-oxo-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-Dioxide. Grades: Highly Purified. CAS No. 154127-41-0. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
4-Sulfamoylbenzoic acid
Carzenide, a Sulfanilamide derivative, could be used as an intermediate to synthesize sorts of pharmaceuticals like carbonicanhydrase inhibitors. Uses: Carzenide could be used as an intermediate to synthesize sorts of pharmaceuticals like carbonicanhydrase inhibitors. Synonyms: 4-sulfamoylbenzoic acid. Grades: > 98 %. CAS No. 138-41-0. Molecular formula: C7H7NO4S. Mole weight: 201.20.
4-Tolylsulfonamide
4-Tolylsulfonamide is a carbonicanhydrase inhibitor used the synthesis of antiglaucoma and anticancer drugs. Group: Biochemicals. Alternative Names: 4-Methyl Benzene sulfonamide; p-Toluenesulfonamide; 4-Methylbenzene-1-sulfonamide; 4-Methyl Benzene sulfonamide; 4- methyl benzensulfonamide; 4- methyl phenylsulfonamide; 4-Tolylsulfonamide; NSC 9908; Plasticizer 15; Toluene-4-sulfonamide; Tolylsulfonamide; Topcizer 1S; Tosylamide; Uniplex 173; p-Methyl Benzene sulfonamide; p-Tolylsulfonamide; p-Tosylamide. Grades: Highly Purified. CAS No. 70-55-3. Pack Sizes: 1g, 10g, 50g, 100g. Molecular Formula: C?H?NO?S, Molecular Weight: 171.22. US Biological Life Sciences.
5-(Acetylimino)-4,5-dihydro-4-methyl-1,3,4-thiadiazole-2-sulfonic Acid is a metabolite of the carbonicanhydrase inhibitor Methazolamide. Group: Biochemicals. Grades: Highly Purified. CAS No. 1312679-00-7. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
6-Ethoxy-2-benzothiazolesulfonamide
Ethoxzolamide is used in the treatment of glaucoma, and is also used as a diuretic, acting as a carbonicanhydrase inhibitor. Uses: Acting as a carbonicanhydrase inhibitor. Synonyms: 6-ethoxy-1,3-benzothiazole-2-sulfonamide. Grades: ≥ 98 %. CAS No. 452-35-7. Molecular formula: C9H10N2O3S2. Mole weight: 258.32.
Acetazolamide
Acetazolamide is a carbonicanhydrase ( CA ) IX inhibitor with an IC 50 of 30 nM for hCA IX. Acetazolamide has diuretic, antihypertensive and anti-gonococcal activities [1] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. CAS No. 59-66-5. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0782.
Acetazolamide
Carbonicanhydrase inhibitor. Diuretic. Group: Biochemicals. Alternative Names: N-[5-Aminosulfonyl)-1,3,4-thiadiazol-2-yl]acetamide; 5-Acetamido-1,3,4-thiadiazole-2-sulfonamide; Acetamox; Atenezol; Defiltran; Diamox; Didoc. Grades: Highly Purified. CAS No. 59-66-5. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
Acetazolamide-[d3]
The isotope labelled form of Acetazolamide which is an effective carbonicanhydrase inhibitor, could be used as a diuretic agent. Synonyms: N-[5-Aminosulfonyl)-1,3,4-thiadiazol-2-yl]acetamide-d3; 5-Acetamido-1,3,4-thiadiazole-2-sulfonamide-d3; Acetamox-d3; Atenezol-d3; Defiltran-d3; Diamox-d3; Didoc-d3. Grades: >98%. CAS No. 1189904-01-5. Molecular formula: C4H3D3N4O3S2. Mole weight: 225.26.
Carbonicanhydrase inhibitor. Diuretic. Group: Biochemicals. Alternative Names: N-[5-Aminosulfonyl)-1,3,4-thiadiazol-2-yl]acetamide-d3; 5-Acetamido-1,3,4-thiadiazole-2-sulfonamide-d3; Acetamox-d3; Atenezol-d3; Defiltran-d3; Diamox-d3; Didoc-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Acetazolamide sodium
Acetazolamide sodium is a carbonicanhydrase ( CA ) IX inhibitor with an IC 50 of 30 nM for hCA IX. Acetazolamide sodium has diuretic, antihypertensive and anti-gonococcal activities [1] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1424-27-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0782A.
Amidosulfonic Acid
Amidosulfonic acid is mainly a precursor to sweet-tasting compounds. It has been used in the design of many types of therapeutic agents such as antibiotics, nucleoside/nucleotide human immunodeficiency virus (HIV) reverse transcriptase inhibitors, HIV protease inhibitors (PIs), anti-cancer drugs (steroid sulfatase and carbonicanhydrase inhibitors), anti-epileptic drugs, and weight loss drugs. Group: Biochemicals. Grades: Highly Purified. CAS No. 5329-14-6. Pack Sizes: 1g, 10g. Molecular Formula: H3NO3S. US Biological Life Sciences.
Worldwide
Benzenesulfonamide
Benzenesulfonamide ia an inhibitor of carbonicanhydrases. Synonyms: Benzenesulfonyl amine; Benzenesulphonamide; M and B 7973; NSC 5341; NSC 85506; Phenylsulfonamide. Grades: ≥95%. CAS No. 98-10-2. Molecular formula: C6H7NO2S. Mole weight: 157.19.
Benzenesulphonamide
Benzenesulphonamide (compound 1) is a potent carbonicanhydrase inhibitor. Benzenesulphonamide shows CA II inhibitory activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 98-10-2. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-101087.
Benzolamide
Benzolamide (CL11366) is a potent carbonicanhydrase (CA) inhibitor, with K i s of 15 nM, 9 nM, 94 nM and 78 nM for hCA I , hCA II , EcoCAγ and VchCAγ , respectively. Benzolamide also inhibits CAS3 , with a K i of 54 nM. Benzolamide can be used for the research of glaucoma and seizures [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CL11366. CAS No. 3368-13-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-118467.
Benzthiazide
Benzthiazide is a long-acting diuretic [1] and a hypertension agent. Benzthiazide is an inhibitor of carbonicanhydrase 9 (CA9) , with K i s of 8.0, 8.8 and 10 nM for CA9, CA2 and CA1, respectively. Benzthiazide also suppresses proliferation of cancer cells [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 91-33-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B1424.
Brinzolamide
Brinzolamide (AL-4862) is a selective carbonicanhydrase II inhibitor with an IC 50 value of 3.2 nM. Brinzolamide hydrochloride reduces intraocular pressure (IOP) by inhibiting ciliary CA-II and decreasing atrial fluid secretion. Brinzolamide can be used in glaucoma disease research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AL-4862. CAS No. 138890-62-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0588.
Brinzolamide-d5
Carbonicanhydrase inhibitor. Antiglaucoma agent. Group: Biochemicals. Alternative Names: (4R)-(Ethylamino-d5)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide; AL-4682-d5; Azopt-d5. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
Brinzolamide Hydrochloride
Carbonicanhydrase inhibitor. Antiglaucoma agent. Group: Biochemicals. Alternative Names: (4R)-4-(Ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-Dioxide Hydrochloride; AL-4682 Hydrochloride; Azopt Hydrochloride. Grades: Highly Purified. CAS No. 150937-43-2. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Bromoacetic-1-13C Acid
Labeled Bromoacetic Acid. Bromoacetic Acid is a relatively strong alkylating agent as well as a versatile building block used very commonly in organic synthesis. Bromoacetic acid has been shown to reversibly inhibit human erythrocyte carbonicanhydrase B. Group: Biochemicals. Alternative Names: 2-Bromoacetic Acid-13C; 2-Bromoethanoic Acid-13C. Grades: Highly Purified. CAS No. 57858-24-9. Pack Sizes: 500mg. US Biological Life Sciences.
Worldwide
Bromoacetic-1,2-13C2 Acid
Labelled Bromoacetic Acid. Bromoacetic Acid is a relatively strong alkylating agent as well as a versatile building block used very commonly in organic synthesis. Bromoacetic acid has been shown to reversibly inhibit human erythrocyte carbonicanhydrase B. Group: Biochemicals. Alternative Names: 1,2-Bromoacetic Acid-13C2; 1,2-Bromoethanoic Acid-13C2. Grades: Highly Purified. CAS No. 52947-00-9. Pack Sizes: 500mg. US Biological Life Sciences.
Worldwide
Bromoacetic Acid
Bromoacetic Acid is a relatively strong alkylating agent as well as a versatile building block used very commonly in organic synthesis. Bromoacetic acid has been shown to reversibly inhibit human erythrocyte carbonicanhydrase B. Group: Biochemicals. Alternative Names: 2-Bromoacetic Acid; 2-Bromoethanoic Acid. Grades: Highly Purified. CAS No. 79-08-3. Pack Sizes: 1g, 10g, 50g. Molecular Formula: C2H3BrO2, Molecular Weight: 138.95. US Biological Life Sciences.
Worldwide
CAIX Inhibitor S4
CAIX Inhibitor S4 is an inhibitor of carbonicanhydrase IX. It is selective for CAIX over CAI and CAII but does inhibit CAXII. It reduced the number of lung metastases, but not primary tumor growth, in an MDA-MB-231 mouse xenograft model. Group: Inhibitors. CAS No. 1330061-67-0. Molecular formula: C15H17N3O4S. Mole weight: 335.38. Appearance: Solid powder. Purity: >98%. IUPACName: 4-(3-(3,5-dimethylphenyl)ureido)phenyl sulfamate. Canonical SMILES: O=S (OC[5]=CC=C (NC (NC[16]=CC (C)=CC (C)=C@16)=O)C=C@6) (N)=O. Catalog: ACM1330061670.
carbonate dehydratase
A zinc protein. Group: Enzymes. Synonyms: carbonicanhydrase; anhydrase; carbonate anhydrase; carbonic acid anhydrase; carboxyanhydrase; carbonicanhydrase A; carbonate hydro-lyase. Enzyme Commission Number: EC 4.2.1.1. CAS No. 9001-03-0. CarbonicAnhydrase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4938; carbonate dehydratase; EC 4.2.1.1; 9001-03-0; carbonicanhydrase; anhydrase; carbonate anhydrase; carbonic acid anhydrase; carboxyanhydrase; carbonicanhydrase A; carbonate hydro-lyase. Cat No: EXWM-4938.
(+/-)-(cis)-Dorzolamide
(+/-)-(cis)-Dorzolamide is an isomer of Dorzolamide. Dorzolamide is a carbonicanhydrase inhibitor. It is an anti-glaucoma agent, and acts by decreasing the production of aqueous humour. Synonyms: (4R,6S)-4-(ethylamino)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide. CAS No. 120279-90-5. Molecular formula: C10H16N2O4S3. Mole weight: 324.44.
Dichlorphenamide
Dichlorphenamide (Diclofenamide) is an orally active, specific, carbonicanhydrase inhibitor. Dichlorphenamide can reduce intraocular pressure by inhibiting the secretion of water from the eye. Dichlorphenamide can be used for glaucoma research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Diclofenamide. CAS No. 120-97-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-B0397.
Dichlorphenamide
Dichlorphenamide is a sulfonamide and a carbonicanhydrase inhibitor of the meta-Disulfamoylbenzene class. Synonyms: Diclofenamide. Grades: >98%. CAS No. 120-97-8. Molecular formula: C6H6Cl2N2O4S2. Mole weight: 305.16.
Diclofenamide
Diclofenamide is a potent carbonicanhydrase inhibitor. Diclofenamide may provide a therapeutic strategy in the inhibition of the human cytosolic isoforms I and II and transmembrane tumor-associated isoenzymes IX and XII. Diclofenamide has been shown to be is effective in the prevention of episodic weakness in both hypokalemic periodic paralysis (HypoPP) and potassium-sensitive periodic paralysis (PSPP). Group: Biochemicals. Alternative Names: 1,3-Disulfamoyl-4,5-dichlorobenzene; 1,3-Disulfamyl-4,5-dichlorobenzene; 3, 4-Dichloro-5-sulfamyl Benzene sulfonamide; 4,5-Dichloro-1,3-disulfamoylbenzene; 4,5-Dichloro-m-benzenedisulfonamide; Antidrasi; CB 8000; Daramide; Daranide; Dichlofenamide; Dichlorophenamide; Dichlorphenamide; Diclofenamid; Glaucol; Oratrol. Grades: Highly Purified. CAS No. 120-97-8. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
Dimethylfraxetin
Dimethylfraxetin is a Carbonicanhydrase inhibitor, with a K i value of 0.0097 μM. Uses: Scientific research. Group: Natural products. Alternative Names: 6,7,8-Trimethoxycoumarin; Fraxetin dimethyl ether. CAS No. 6035-49-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N0085.
Dorzolamide
Carbonicanhydrase inhibitor. Antiglaucoma agent. Group: Biochemicals. Alternative Names: (4S,6S)-. Grades: Highly Purified. CAS No. 130693-82-2. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Dorzolamide hydrochloride
Dorzolamide (L671152) hydrochloride is a potent carbonicanhydrase II inhibitor, with IC 50 values of 0.18 nM and 600 nM for red blood cell CA-II and CA-I respectively. Dorzolamide possesses anti-tumor activity [1]. Uses: Scientific research. Group: Natural products. Alternative Names: L671152 hydrochloride; MK507 hydrochloride. CAS No. 130693-82-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 100 mg; 250 mg. Product ID: HY-B0109A.
Dorzolamide Impurity A
Dorzolamide is a potent carbonicanhydrase II inhibitor with an IC50 value of 0.16 nM on human erythrocyte carbonicanhydrase II in vitro. It has been found to lower increased intraocular pressure in open-angle glaucoma and ocular hypertension. Uses: Carbonicanhydrase inhibitors. Synonyms: L671152; MK507; L 671152; MK 507; L-671152; MK-507; Trusopt. Grades: >98%. CAS No. 120279-96-1. Molecular formula: C10H16N2O4S3. Mole weight: 324.44.
DTA
DTA (2,4-Disulfamyl-5-trifluoromethylaniline) is a cyclic AMP phosphodiesterase inhibitor that binds to erythrocyte carbonicanhydrase [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 2,4-Disulfamyl-5-trifluoromethylaniline. CAS No. 654-62-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W011293.
DTP348
DTP348 is an oral dual CAIX inhibitor/ radiosensitizer. DTP348 is an oral dual drug with two mechanisms of action: (1) carbonicanhydrase IX inhibitor which acidifies the intracellular pH through the sulfamide components; (2) radio sensitizer of hypoxic cells through its 5-nitroimidazole moiety. Synonyms: DTP 348; DTP-348; 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethylsulfamide; 1-(2-Sulfamidoethyl)-2-methyl-5-nitroimidazole. CAS No. 1383370-92-0. Molecular formula: C6H11N5O4S. Mole weight: 249.24.
Fluorometholone acetate
Fluorometholone acetate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester. Fluorometholone acetate potently inhibits carbonicanhydrase (CA) with IC 50 s of 2.18 μM and 17.5 μM for hCA-I and hCA-II , respectively. Fluorometholone acetate has anti-inflammatory effect and has the potential for external ocular inflammation research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3801-6-7. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-B1471.
Furosemide Impurity F
Furosemide Impurity F is used as a carbonicanhydrase inhibitor inhibiting human, bacterial and archaeal isozymes. Synonyms: Tetrahydro Furosemide; 4-Chloro-5-sulfamoyl-N-(tetrahydrofurfuryl)anthranilic Acid; 4-Chloro-5-Sulfamoyl-2-[[((2RS)-Tetrahydrofuran-2-yl)methyl]amino]Benzoic Acid. Grades: > 95%. CAS No. 4793-38-8. Molecular formula: C12H15ClN2O5S. Mole weight: 334.78.
Girentuximab
Girentuximab (G250) is a chimeric monoclonal antibody that binds carbonicanhydrase IX (CAIX) , a cell surface glycoprotein ubiquitously expressed in clear cell renal cell carcinoma (ccRCC) [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: G250; cG250. CAS No. 916138-87-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99023.
Girentuximab
Girentuximab is a chimeric monoclonal antibody that binds to carbonicanhydrase IX (CAIX), a cell-surface glycoprotein expressed on clear-cell RCC but not on normal kidney cells. Synonyms: G250; cG250. CAS No. 916138-87-9.
Halazone
Halazone is an atypical antimicrobial sulfonamide derivative and a carbonicanhydrase II inhibitor with a K d value of 1.45 μM. Halazone protects sodium channels from inactivation. Halazone is widely used for disinfection of drinking water [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 80-13-7. Pack Sizes: 50 mg; 100 mg; 250 mg. Product ID: HY-B1386.
Hydrochlorothiazide
Hydrochlorothiazide is a carbonicanhydrase inhibitor used as a diuretic medication. Hydrochlorothiazide can be used to treat hypertension and fluid retention (edema). Synonyms: HCTZ. CAS No. 58-93-5. Molecular formula: C7H8ClN3O4S2. Mole weight: 297.7.
A labeled carbonicanhydrase inhibitor. Group: Biochemicals. Alternative Names: 6-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-13c1,d2-7-sulfonamide 1,1-Dioxide. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
A carbonicanhydrase inhibitor. Group: Biochemicals. Alternative Names: 6-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-Dioxide. Grades: Highly Purified. Pack Sizes: 10g. US Biological Life Sciences.
Worldwide
Indisulam
Indisulam (E 7070) is a carbonicanhydrase inhibitor with anticancer activity. Indisulam (E 7070) is a sulfonamide agent that targets the G1 phase of the cell cycle. Indisulam (E 7070) causes a blockade in the G1/S transition through inhibition of the activation of both CDK2 and cyclin E. Indisulam (E 7070) targets splicing by inducing RBM39 degradation via recruitment to DCAF15 [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: E 7070. CAS No. 165668-41-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-13650.
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