Carbonic Anhydrase Suppliers USA
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Product | Description | |
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Carbonic anhydrase 9 (254-262) Quick inquiry Where to buy Suppliers range | Carbonic anhydrase 9. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-330. | |
Carbonic Anhydrase IX/XII Inhibitor (CAIX Inhibitor) Quick inquiry Where to buy Suppliers range | A cell permeable benzenesulfonamide Carbonic Anhydrase (CA) inhibitor that is selective for human hCA IX and hCA XII (Ki = 0.9nM and 5.7nM, respectively) against two other physiologically relevant hCA isoforms (Ki = 23.4nM and 15nM for hCA I and hCA II, respectively), as compared with another CA inhibitor AAZ (Ki = 250nM, 12nM, 25nM, and 5.7nM for hCA I, hCA II, hCA IX, and hCA XII, respectively). It is shown to effectively inhibit the formation of metastases by 4T1 breast cancer cells in a mouse model dose-dependently at pharmacologic concentrations of 15-45mg/kg. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
Carbonic Anhydrase IX/XII Inhibitor II, U-104 (CAIX Inhibitor II) Quick inquiry Where to buy Suppliers range | A cell permeable ureido-sulfonamide Carbonic Anhydrase (CA) inhibitor that is selective for human hCA IX and hCA XII (KiEnM and 4.5nM, respectively) against two other physiologically relevant hCA isoforms (KiP80nM and 9640nM for hCA I and hCA II, respectively). It elicits anti-tumor growth effects dose-dependently from 19 to 38mg/kg in a mouse tumor growth model implanted with MDA-MB-231 LM2-4Luc+ cells, and demonstrates metastasis inhibition in a mouse metastasis model injected with 4T1 cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
CA6, Positive Control (Carbonic Anhydrase 6, Carbonate Dehydratase VI, Carbonic Anhydrase VI, CA-VI, Salivary Carbonic Anhydrase, Secreted Carbonic Anhydrase) Quick inquiry Where to buy Suppliers range | Control for 139560. Group: Molecular Biology. Pack Sizes: 15ul. US Biological Life Sciences. | Worldwide |
1-(2-(Benzylthio)-5-chlorothiophen-3-yl)ethanone Quick inquiry Where to buy Suppliers range | Reagent used in the preparation of carbonic anhydrase inhibitors. Group: Biochemicals. Alternative Names: 1-[5-Chloro-2-[(phenylmethyl)thio]-3-thienyl]ethanone. Grades: Highly Purified. CAS No. 160982-09-2. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
1-(2-Sulfamidoethyl)-2-methyl-5-nitroimidazole Quick inquiry Where to buy Suppliers range | 1-(2-Sulfamidoethyl)-2-methyl-5-nitroimidazole is a hypoxia-targeting carbonic anhydrase IX inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1383370-92-0. Pack Sizes: 100mg, 1g. Molecular Formula: C6H11N5O4S, Molecular Weight: 249.25. US Biological Life Sciences. | Worldwide |
1-Amino-3-Hydroxybenzene Quick inquiry Where to buy Suppliers range | 1-Amino-3-Hydroxybenzene is used in the preparation of inhibitors of mammalian carbonic anhydrase isoforms. Also used in the preparation of quinoline tethered fluorescent carbon dots for regulated anticancer discovery. Group: Biochemicals. Grades: Highly Purified. CAS No. 591-27-5. Pack Sizes: 10g, 50g. Molecular Formula: C6H7NO. US Biological Life Sciences. | Worldwide |
2,3-Difluorobenzoic Acid Quick inquiry Where to buy Suppliers range | 2,3-Difluorobenzoic acid is the difluorinated analogue of Benzoic acid (B203900). 2,3-Difluorobenzoic acid is a useful synthetic intermediate and is used as a starting material to synthesize thioether benzenesulfonamide inhibitors of carbonic anhydrases II and IV. Group: Biochemicals. Grades: Highly Purified. CAS No. 4519-39-5. Pack Sizes: 2.5g, 10 g. Molecular Formula: C7H4F2O2, Molecular Weight: 158.1. US Biological Life Sciences. | Worldwide |
2-(3-methoxypropyl)-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide Quick inquiry Where to buy Suppliers range | An impurity of Brinzolamide, a potent carbonic anhydrase inhibitor used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension. Synonyms: 2-(3-METHOXYPROPYL)-2H-THIENO[3,2-E][1,2]THIAZINE-6-SULFONAMIDE 1,1-DIOXIDE; 2-(3-methoxypropyl)-1,1-dioxothieno[3,2-e]thiazine-6-sulfonamide; B0464-284943; 2-(3-METHOXYPROPYL)-2H-THIENO[3,2-E][1,2]THIAZINE-6-SULFONAMIDE1,1-DIOXIDE. CAS No. 171273-35-1. Molecular formula: C10H14N2O5S3. Mole weight: 338.42. | |
2,4-Disulfamyl-5-trifluoromethylaniline Quick inquiry Where to buy Suppliers range | 2,4-Disulfamyl-5-trifluoromethylaniline is a carbonic anhydrase inhibitor, used as a potential anti-tumor and antiglaucoma drug. Metabolite of hydroflumethazide, a diuretic. Group: Biochemicals. Grades: Highly Purified. CAS No. 654-62-6. Pack Sizes: 1g, 5g. Molecular Formula: C7H8F3N3O4S2. US Biological Life Sciences. | Worldwide |
2-Aminobenzenesulfonamide Quick inquiry Where to buy Suppliers range | 2-Aminobenzenesulfonamide is a potent inhibitor of carbonic anhydrase B. Synonyms: 2-aminobenzenesulfonamide. Grades: 98 %. CAS No. 3306-62-5. Molecular formula: C6H8N2O2S. Mole weight: 172.20. | |
2-Desaminosulfonyl 3-Aminosulfonyl Dorzolamide Quick inquiry Where to buy Suppliers range | 2-Desaminosulfonyl 3-Aminosulfonyl Dorzolamide is a useful synthetic compound. Also, it is derived from (4R,6S)-5,6-Dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-4-ol 7,7-Dioxide (T344510), which is an analog of topically-active carbonic anhydrase inhibitor MK-507, commonly known Dorzolamide (D535100). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2mg. Molecular Formula: C10H16N2O4S3. US Biological Life Sciences. | Worldwide |
2-Desaminosulfonyl 3-Aminosulfonyl N-Acetyl Dorzolamide Quick inquiry Where to buy Suppliers range | 2-Desaminosulfonyl 3-Aminosulfonyl N-Acetyl Dorzolamide is an intermediate in the synthesis of 2-Desaminosulfonyl 3-Aminosulfonyl Dorzolamide (D288235), which is derived from (4R,6S)-5,6-Dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-4-ol 7,7-Dioxide (T344510), which is an analog of topically-active carbonic anhydrase inhibitor MK-507, commonly known Dorzolamide (D535100). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C12H18N2O5S3. US Biological Life Sciences. | Worldwide |
2-Hydroxyethanesulfonic Acid Quick inquiry Where to buy Suppliers range | 2-Hydroxyethanesulfonic Acid is a reactant in the synthesis of 4-substituted-2, 3, 5, 6-tetrafluorobene zene sulfonamides as inhibitors of carbonic anhydrases I, II, VII, XII, and XIII. Group: Biochemicals. Grades: Highly Purified. CAS No. 107-36-8. Pack Sizes: 1g, 10g. Molecular Formula: C2H6O4S. US Biological Life Sciences. | Worldwide |
2-Methyl-5-nitrobenzenesulfonamide Quick inquiry Where to buy Suppliers range | 2-Methyl-5-nitrobenzenesulfonamide (CAS# 6269-91-6) is a chemical reagent in the synthesis of good inhibitors of cancer-related carbonic anhydrase. Also used in the synthesis of novel deacetylase inhibitors used in anti-tumor therapy. Synonyms: 2-methyl-5-nitrobenzenesulfonamide; 2-methyl-5-nitrobenzenesulfonamide. Grades: 98 %. CAS No. 6269-91-6. Molecular formula: C7H8N2O4S. Mole weight: 216.21. | |
2-Methyl-5-nitro Benzene sulfonamide Quick inquiry Where to buy Suppliers range | 2-Methyl-5-nitro Benzene sulfonamide is a chemical reagent in the synthesis of good inhibitors of cancer-related carbonic anhydrase. Also used in the synthesis of novel deacetylase inhibitors used in anti-tumor therapy. Group: Biochemicals. Grades: Highly Purified. CAS No. 6269-91-6. Pack Sizes: 1g, 5g. Molecular Formula: C7H8N2O4S, Molecular Weight: 216.21. US Biological Life Sciences. | Worldwide |
2-Nitro-benzenesulfonamide Quick inquiry Where to buy Suppliers range | 2-Nitro-benzenesulfonamide is a carbonic anhydrase inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 5455-59-4. Pack Sizes: 1g, 5g. Molecular Formula: C6H6N2O4S, Molecular Weight: 202.19. US Biological Life Sciences. | Worldwide |
3-Acetyl-5-chloro-2-thiophenesulfonamide Quick inquiry Where to buy Suppliers range | 3-Acetyl-5-chloro-2-thiophenesulfonamide is a reactant used in the preparation of heteroaryl chalcones as potent antimicrobial agents and Brinzolamide (B677600), a topical carbonic anhydrase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 160982-10-5. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
4-Desethylamino 4-oxobrinzolamide Quick inquiry Where to buy Suppliers range | 4-Desethylamino 4-oxobrinzolamide is an impurity of Brinzolamide (B677600), a carbonic anhydrase inhibitor and a antiglaucoma agent. Group: Biochemicals. Alternative Names: 3,4-Dihydro-2-(3-methoxypropyl)-4-oxo-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-Dioxide. Grades: Highly Purified. CAS No. 154127-41-0. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
4-Sulfamoylbenzoic acid Quick inquiry Where to buy Suppliers range | Carzenide, a Sulfanilamide derivative, could be used as an intermediate to synthesize sorts of pharmaceuticals like carbonic anhydrase inhibitors. Uses: Carzenide could be used as an intermediate to synthesize sorts of pharmaceuticals like carbonic anhydrase inhibitors. Synonyms: 4-sulfamoylbenzoic acid. Grades: > 98 %. CAS No. 138-41-0. Molecular formula: C7H7NO4S. Mole weight: 201.20. | |
4-Tolylsulfonamide Quick inquiry Where to buy Suppliers range | 4-Tolylsulfonamide is a carbonic anhydrase inhibitor used the synthesis of antiglaucoma and anticancer drugs. Group: Biochemicals. Alternative Names: 4-Methyl Benzene sulfonamide; p-Toluenesulfonamide; 4-Methylbenzene-1-sulfonamide; 4-Methyl Benzene sulfonamide; 4- methyl benzensulfonamide; 4- methyl phenylsulfonamide; 4-Tolylsulfonamide; NSC 9908; Plasticizer 15; Toluene-4-sulfonamide; Tolylsulfonamide; Topcizer 1S; Tosylamide; Uniplex 173; p-Methyl Benzene sulfonamide; p-Tolylsulfonamide; p-Tosylamide. Grades: Highly Purified. CAS No. 70-55-3. Pack Sizes: 1g, 10g, 50g, 100g. Molecular Formula: C?H?NO?S, Molecular Weight: 171.22. US Biological Life Sciences. | Worldwide |
5-(Acetylimino)-4,5-dihydro-4-methyl-1,3,4-thiadiazole-2-sulfonic Acid Quick inquiry Where to buy Suppliers range | 5-(Acetylimino)-4,5-dihydro-4-methyl-1,3,4-thiadiazole-2-sulfonic Acid is a metabolite of the carbonic anhydrase inhibitor Methazolamide. Group: Biochemicals. Grades: Highly Purified. CAS No. 1312679-00-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
6-Ethoxy-2-benzothiazolesulfonamide Quick inquiry Where to buy Suppliers range | Ethoxzolamide is used in the treatment of glaucoma, and is also used as a diuretic, acting as a carbonic anhydrase inhibitor. Uses: Acting as a carbonic anhydrase inhibitor. Synonyms: 6-ethoxy-1,3-benzothiazole-2-sulfonamide. Grades: ≥ 98 %. CAS No. 452-35-7. Molecular formula: C9H10N2O3S2. Mole weight: 258.32. | |
Acetazolamide Quick inquiry Where to buy Suppliers range | Acetazolamide. Uses: Carbonic anhydrase inhibitors. Group: Active Pharmaceutical Ingredients (APIs). Approvals: Chinese Pharmacopoeia 2015 Edition Part 2. CAS No. 59-66-5. Product ID: ACM59665. | |
Acetazolamide Quick inquiry Where to buy Suppliers range | Carbonic anhydrase inhibitor. Diuretic. Group: Biochemicals. Alternative Names: N-[5-Aminosulfonyl)-1,3,4-thiadiazol-2-yl]acetamide; 5-Acetamido-1,3,4-thiadiazole-2-sulfonamide; Acetamox; Atenezol; Defiltran; Diamox; Didoc. Grades: Highly Purified. CAS No. 59-66-5. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
Acetazolamide-[d3] Quick inquiry Where to buy Suppliers range | The isotope labelled form of Acetazolamide which is an effective carbonic anhydrase inhibitor, could be used as a diuretic agent. Synonyms: N-[5-Aminosulfonyl)-1,3,4-thiadiazol-2-yl]acetamide-d3; 5-Acetamido-1,3,4-thiadiazole-2-sulfonamide-d3; Acetamox-d3; Atenezol-d3; Defiltran-d3; Diamox-d3; Didoc-d3. Grades: >98%. CAS No. 1189904-01-5. Molecular formula: C4H3D3N4O3S2. Mole weight: 225.26. | |
Acetazolamide-d3 (N-[5-Aminosulfonyl)-1,3,4-thiadiazol-2-yl]acetamide-d3, 5-Acetamido-1,3,4-thiadiazole-2-sulfonamide-d3, Acetamox-d3, Atenezol-d3, Defiltran-d3, Diamox-d3, Didoc-d3) Quick inquiry Where to buy Suppliers range | Carbonic anhydrase inhibitor. Diuretic. Group: Biochemicals. Alternative Names: N-[5-Aminosulfonyl)-1,3,4-thiadiazol-2-yl]acetamide-d3; 5-Acetamido-1,3,4-thiadiazole-2-sulfonamide-d3; Acetamox-d3; Atenezol-d3; Defiltran-d3; Diamox-d3; Didoc-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Amidosulfonic Acid Quick inquiry Where to buy Suppliers range | Amidosulfonic acid is mainly a precursor to sweet-tasting compounds. It has been used in the design of many types of therapeutic agents such as antibiotics, nucleoside/nucleotide human immunodeficiency virus (HIV) reverse transcriptase inhibitors, HIV protease inhibitors (PIs), anti-cancer drugs (steroid sulfatase and carbonic anhydrase inhibitors), anti-epileptic drugs, and weight loss drugs. Group: Biochemicals. Grades: Highly Purified. CAS No. 5329-14-6. Pack Sizes: 1g, 10g. Molecular Formula: H3NO3S. US Biological Life Sciences. | Worldwide |
Benzenesulfonamide Quick inquiry Where to buy Suppliers range | Benzenesulfonamide ia an inhibitor of carbonic anhydrases. Synonyms: Benzenesulfonyl amine; Benzenesulphonamide; M and B 7973; NSC 5341; NSC 85506; Phenylsulfonamide. Grades: ≥95%. CAS No. 98-10-2. Molecular formula: C6H7NO2S. Mole weight: 157.19. | |
Brinzolamide Quick inquiry Where to buy Suppliers range | Brinzolamide is a carbonic anhydrase inhibitor used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension. Uses: API. CAS No. 138890-62-7. Product ID: 10-101-134. | |
Brinzolamide-d5 Quick inquiry Where to buy Suppliers range | Carbonic anhydrase inhibitor. Antiglaucoma agent. Group: Biochemicals. Alternative Names: (4R)-(Ethylamino-d5)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide; AL-4682-d5; Azopt-d5. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
Brinzolamide Hydrochloride Quick inquiry Where to buy Suppliers range | Carbonic anhydrase inhibitor. Antiglaucoma agent. Group: Biochemicals. Alternative Names: (4R)-4-(Ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-Dioxide Hydrochloride; AL-4682 Hydrochloride; Azopt Hydrochloride. Grades: Highly Purified. CAS No. 150937-43-2. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
Bromoacetic-1-13C Acid Quick inquiry Where to buy Suppliers range | Labeled Bromoacetic Acid. Bromoacetic Acid is a relatively strong alkylating agent as well as a versatile building block used very commonly in organic synthesis. Bromoacetic acid has been shown to reversibly inhibit human erythrocyte carbonic anhydrase B. Group: Biochemicals. Alternative Names: 2-Bromoacetic Acid-13C; 2-Bromoethanoic Acid-13C. Grades: Highly Purified. CAS No. 57858-24-9. Pack Sizes: 500mg. US Biological Life Sciences. | Worldwide |
Bromoacetic-1,2-13C2 Acid Quick inquiry Where to buy Suppliers range | Labelled Bromoacetic Acid. Bromoacetic Acid is a relatively strong alkylating agent as well as a versatile building block used very commonly in organic synthesis. Bromoacetic acid has been shown to reversibly inhibit human erythrocyte carbonic anhydrase B. Group: Biochemicals. Alternative Names: 1,2-Bromoacetic Acid-13C2; 1,2-Bromoethanoic Acid-13C2. Grades: Highly Purified. CAS No. 52947-00-9. Pack Sizes: 500mg. US Biological Life Sciences. | Worldwide |
Bromoacetic Acid Quick inquiry Where to buy Suppliers range | Bromoacetic Acid is a relatively strong alkylating agent as well as a versatile building block used very commonly in organic synthesis. Bromoacetic acid has been shown to reversibly inhibit human erythrocyte carbonic anhydrase B. Group: Biochemicals. Alternative Names: 2-Bromoacetic Acid; 2-Bromoethanoic Acid. Grades: Highly Purified. CAS No. 79-08-3. Pack Sizes: 1g, 10g, 50g. Molecular Formula: C2H3BrO2, Molecular Weight: 138.95. US Biological Life Sciences. | Worldwide |
(+/-)-(cis)-Dorzolamide Quick inquiry Where to buy Suppliers range | (+/-)-(cis)-Dorzolamide is an isomer of Dorzolamide. Dorzolamide is a carbonic anhydrase inhibitor. It is an anti-glaucoma agent, and acts by decreasing the production of aqueous humour. Synonyms: (4R,6S)-4-(ethylamino)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide. CAS No. 120279-90-5. Molecular formula: C10H16N2O4S3. Mole weight: 324.44. | |
Dichlorphenamide Quick inquiry Where to buy Suppliers range | Dichlorphenamide is a sulfonamide and a carbonic anhydrase inhibitor of the meta-Disulfamoylbenzene class. Synonyms: Diclofenamide. Grades: >98%. CAS No. 120-97-8. Molecular formula: C6H6Cl2N2O4S2. Mole weight: 305.16. | |
Diclofenamide Quick inquiry Where to buy Suppliers range | Diclofenamide is a potent carbonic anhydrase inhibitor. Diclofenamide may provide a therapeutic strategy in the inhibition of the human cytosolic isoforms I and II and transmembrane tumor-associated isoenzymes IX and XII. Diclofenamide has been shown to be is effective in the prevention of episodic weakness in both hypokalemic periodic paralysis (HypoPP) and potassium-sensitive periodic paralysis (PSPP). Group: Biochemicals. Alternative Names: 1,3-Disulfamoyl-4,5-dichlorobenzene; 1,3-Disulfamyl-4,5-dichlorobenzene; 3, 4-Dichloro-5-sulfamyl Benzene sulfonamide; 4,5-Dichloro-1,3-disulfamoylbenzene; 4,5-Dichloro-m-benzenedisulfonamide; Antidrasi; CB 8000; Daramide; Daranide; Dichlofenamide; Dichlorophenamide; Dichlorphenamide; Diclofenamid; Glaucol; Oratrol. Grades: Highly Purified. CAS No. 120-97-8. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
Dorzolamide Quick inquiry Where to buy Suppliers range | Carbonic anhydrase inhibitor. Antiglaucoma agent. Group: Biochemicals. Alternative Names: (4S,6S)-. Grades: Highly Purified. CAS No. 130693-82-2. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
Dorzolamide Impurity A Quick inquiry Where to buy Suppliers range | Dorzolamide is a potent carbonic anhydrase II inhibitor with an IC50 value of 0.16 nM on human erythrocyte carbonic anhydrase II in vitro. It has been found to lower increased intraocular pressure in open-angle glaucoma and ocular hypertension. Uses: Carbonic anhydrase inhibitors. Synonyms: L671152; MK507; L 671152; MK 507; L-671152; MK-507; Trusopt. Grades: >98%. CAS No. 120279-96-1. Molecular formula: C10H16N2O4S3. Mole weight: 324.44. | |
DTP348 Quick inquiry Where to buy Suppliers range | DTP348 is an oral dual CAIX inhibitor/ radiosensitizer. DTP348 is an oral dual drug with two mechanisms of action: (1) carbonic anhydrase IX inhibitor which acidifies the intracellular pH through the sulfamide components; (2) radio sensitizer of hypoxic cells through its 5-nitroimidazole moiety. Synonyms: DTP 348; DTP-348; 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethylsulfamide; 1-(2-Sulfamidoethyl)-2-methyl-5-nitroimidazole. CAS No. 1383370-92-0. Molecular formula: C6H11N5O4S. Mole weight: 249.24. | |
Furosemide Impurity F Quick inquiry Where to buy Suppliers range | Furosemide Impurity F is used as a carbonic anhydrase inhibitor inhibiting human, bacterial and archaeal isozymes. Synonyms: Tetrahydro Furosemide; 4-Chloro-5-sulfamoyl-N-(tetrahydrofurfuryl)anthranilic Acid; 4-Chloro-5-Sulfamoyl-2-[[((2RS)-Tetrahydrofuran-2-yl)methyl]amino]Benzoic Acid. Grades: > 95%. CAS No. 4793-38-8. Molecular formula: C12H15ClN2O5S. Mole weight: 334.78. | |
Girentuximab Quick inquiry Where to buy Suppliers range | Girentuximab is a chimeric monoclonal antibody that binds to carbonic anhydrase IX (CAIX), a cell-surface glycoprotein expressed on clear-cell RCC but not on normal kidney cells. Synonyms: G250; cG250. CAS No. 916138-87-9. | |
Hydrochlorothiazide Quick inquiry Where to buy Suppliers range | Hydrochlorothiazide is a carbonic anhydrase inhibitor used as a diuretic medication. Hydrochlorothiazide can be used to treat hypertension and fluid retention (edema). Synonyms: HCTZ. CAS No. 58-93-5. Molecular formula: C7H8ClN3O4S2. Mole weight: 297.7. | |
Hydrochlorothiazide-13c1,d2 (6-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-13c1,d2-7-sulfonamide 1,1-Dioxide) Quick inquiry Where to buy Suppliers range | A labeled carbonic anhydrase inhibitor. Group: Biochemicals. Alternative Names: 6-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-13c1,d2-7-sulfonamide 1,1-Dioxide. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
Hydrochlorothiazide (6-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-Dioxide) Quick inquiry Where to buy Suppliers range | A carbonic anhydrase inhibitor. Group: Biochemicals. Alternative Names: 6-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-Dioxide. Grades: Highly Purified. Pack Sizes: 10g. US Biological Life Sciences. | Worldwide |
Indisulam Quick inquiry Where to buy Suppliers range | Indisulam is a carbonic anhydrase inibitor. It is a molecular glue that degrades mRNA splicing factor RBM39. Uses: Antineoplastic agents. Synonyms: E7070; E 7070; E-7070; ER35744; ER 35744; ER-35744; D04522; Indisulam. Grades: ≥98% (HPLC). CAS No. 165668-41-7. Molecular formula: C14H12ClN3O4S2. Mole weight: 385.84. | |
KC7F2 (N,N'-(Dithiodi-2,1-ethanediyl)bis[2, 5-dichloro Benzene sulfonamide) Quick inquiry Where to buy Suppliers range | Inhibitor of HIF-1alpha. Thought to act via down-regulation of HIF-1alpha protein synthesis; reduces phosphorylation of eIF4E binding protein 1 (4EBP1) and p70 S6K in hypoxic conditions. Also blocks hypoxia-induced HIF-1alpha accumulation in a range of human cancer cell lines. Inhibits the expression of HIF target genes, such as carbonic anhydrase IX and MMP2. Group: Biochemicals. Grades: Highly Purified. CAS No. 927822-86-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
KCN1 Quick inquiry Where to buy Suppliers range | KCN1, a novel synthetic sulfonamide, is a HIF pathway inhibitor with potential anticancer activity in vitro and in vivo anti-pancreatic cancer activities and preclinical pharmacology. KCN1 specifically inhibited HIF reporter gene activity in several glioma cell lines at the nanomolar level. KCN1 also downregulated transcription of endogenous HIF-1 target genes, such as VEGF, Glut-1, and carbonic anhydrase 9, in a hypoxia-responsive element (HRE)-dependent manner. KCN1 potently inhibited the growth of subcutaneous malignant glioma tumor xenografts with minimal adverse effects on the host. Mechanistically, KCN1 did not downregulate the levels of HIF-1α or other components of the HIF transcriptional complex; rather, it antagonized hypoxia-inducible transcription by disrupting the interaction of HIF-1α with transcriptional coactivators p300/CBP.CONCLUSIONS: The new HIF pathway inhibitor KCN1 has antitumor activity in mouse models, supporting its further translation for the treatment of human tumors displaying hypoxia or HIF overexpression. Synonyms: KCN-1; 3,4-dimethoxy-N-((2,2-dimethyl-2H-chromen-6-yl)methyl)-N-phenylbenzenesulfonamide. CAS No. 927823-01-6. Molecular formula: C26H27NO5S. Mole weight: 465.561. | |
Methazolamide Quick inquiry Where to buy Suppliers range | Methazolamide is a carbonic anhydrase inhibitor with Ki of 50 nM, 14 nM and 36 nM for hCA I, hCA II and bCA IV isoforms, respectively. Uses: Carbonic anhydrase inhibitors; diuretics. Synonyms: CL 8490; CL8490; CL-8490. Grades: >98%. CAS No. 554-57-4. Molecular formula: C5H8N4O3S2. Mole weight: 236.27. | |
Methazolamide Quick inquiry Where to buy Suppliers range | Methazolamide is a carbonic anhydrase inhibitor. Methazolamide is used in the treatment of glaucoma. Group: Biochemicals. Alternative Names: N-[5-(aminosulfonyl)-3-methyl-1,3,4-thiadiazol-2(3H)-ylidene]acetamide;5-Acetylimino-4-methyl-Δ2-1,3,4-thiadiazoline-2-sulfonamide; L 584601; N-(4-Methyl-2-sulfamoyl-Δ2-1,3,4-thiadiazolin-5-ylidene)acetamide; Methenamide; Neptazane; Neptazaneat. Grades: Highly Purified. CAS No. 554-57-4. Pack Sizes: 2.5g. US Biological Life Sciences. | Worldwide |
Methazolamide Sulfonic Acid Quick inquiry Where to buy Suppliers range | Methazolamide Sulfonic Acid is a metabolite of the carbonic anhydrase inhibitor Methazolamide. Synonyms: 5-(Acetylimino)-4,5-dihydro-4-methyl-1,3,4-thiadiazole-2-sulfonic Acid. Grades: > 95%. CAS No. 1312679-00-7. Molecular formula: C5H7N3O4S2. Mole weight: 237.26. | |
N1-[2-(1-Piperazinyl)ethyl]-1,2-ethanediamine Quick inquiry Where to buy Suppliers range | N1-[2-(1-Piperazinyl)ethyl]-1,2-ethanediamine is an impurity of Diethylenetriamine (D444255); a compound that is used in biological studies for polyamines inhibition to carbonic anhydrases by anchoring to the zinc-coordinated water molecule. Group: Biochemicals. Grades: Highly Purified. CAS No. 24028-46-4. Pack Sizes: 10mg, 100mg. Molecular Formula: C8H20N4, Molecular Weight: 172.27. US Biological Life Sciences. | Worldwide |
N-[2-(4-oxo-4H-3,1-benzoxazin-2-yl)phenyl]-2-naphthalenesulfonamide Quick inquiry Where to buy Suppliers range | N-[2-(4-oxo-4H-3,1-benzoxazin-2-yl)phenyl]-2-naphthalenesulfonamide, a profound small molecule inhibitor designed to target Cancerous Enzyme Carbonic Anhydrase IX (CAIX). This molecule is capable of exhibiting its potential therapeutic efficacy against various malignancies in numerous body sites including Breast, Prostate, and Kidney. This inhibitor is highly recommended due to its ability to repress the CAIX activity, a pivotal catalyst responsible for tumor inception, advancement, and invasion, rendering it a glimmer of hope as a Cancer treatment. Synonyms: oxobenzoxazinyl naphthalene sulfoanilide; 2-Naphthalenesulfonamide, N-[2-(4-oxo-4H-3,1-benzoxazin-2-yl)phenyl]-. CAS No. 10128-55-9. Molecular formula: C24H16N2O4S. Mole weight: 428.46. | |
Polmacoxib Quick inquiry Where to buy Suppliers range | Polmacoxib is a first-in-class NSAID drug candidate that acts as a dual inhibitor of COX-2 and carbonic anhydrase (CA). It exhibits superior safety for cardiovascular, renal, and gastrointestinal tissues due to its dual COX-2 and CA binding properties. Polmacoxib inhibits premalignant and malignant colorectal lesions in mouse models, partly through inhibiting tumor cell proliferation. Synonyms: CG100649; CG-100649; CG 100649; polmacoxib; 4-[3-(3-fluorophenyl)-5,5-dimethyl-4-oxofuran-2-yl]benzenesulfonamide. Grades: > 98%. CAS No. 301692-76-2. Molecular formula: C18H16FNO4S. Mole weight: 361.387. | |
p-Toluenesulfonamide Quick inquiry Where to buy Suppliers range | 4-Tolylsulfonamide is a carbonic anhydrase inhibitor used the synthesis of antiglaucoma and anticancer drugs. Group: Biochemicals. Grades: Highly Purified. CAS No. 70-55-3. Pack Sizes: 1kg, 2kg, 5kg, 10kg. Molecular Formula: C7H9NO2S, Molecular Weight: 171.22. US Biological Life Sciences. | Worldwide |
quinethazone Quick inquiry Where to buy Suppliers range | Quinethazone is a thiazide-like diuretic. It is a carbonic anhydrase inhibitor and can be used for the treatment of hypertension. Uses: Hypertension. Synonyms: 2-Ethyl-7-chloro-1,2,3,4-tetrahydro-4-oxoquinazoline-6-sulfonamide; 2-Ethyl-7-chloro-2,3-dihydro-4(1H)-quinazolone-6-sulfonamide; Aquamox; CL 36010; Hydromox; Idrokin; Quimethazin; Quinethazon; Quinethazonum; 7-Chloro-2-ethyl-1,2,3,4-tetrahydro-4-oxo-6-quinazolinesulfonamide; 7-Chloro-2-ethyl-1,2,3,4-tetrahydro-4-oxo-6-sulfamoylquinazoline; 7-Chloro-2-ethyl-6-sulfamyl-1,2,3,4-tetrahydro-4-quinazolinone. Grades: 98%. CAS No. 73-49-4. Molecular formula: C10H12ClN3O3S. Mole weight: 289.74. | |
(R)-4-Hydroxy-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-Dioxide Quick inquiry Where to buy Suppliers range | An impurity of Brinzolamide, a potent carbonic anhydrase inhibitor used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension. Synonyms: (R)-4-HYDROXY-2-(3-METHOXYPROPYL)-3,4-DIHYDRO-2H-THIENO[3,2-E][1,2]THIAZINE-6-SULFONAMIDE 1,1-DIOXIDE; (4R)-4-hydroxy-2-(3-methoxypropyl)-1,1-dioxo-3,4-dihydrothieno[3,2-e]thiazine-6-sulfonamide; SCHEMBL3576264; (R)-4-HYDROXY-2-(3-METHOXYPROPYL)-3,4-DIHYDRO-2H-THIENO[3,2-E][1,2]THIAZINE-6-SULFONAMIDE1,1-DIOXIDE. CAS No. 165117-54-4. Molecular formula: C10H16N2O6S3. Mole weight: 356.44. | |
R9-TAT Quick inquiry Where to buy Suppliers range | R9-Tat is the arginine-substituted analogue for the HIV Tat protein (48-60). Similar to Tat (48-60), R9-Tat is internalized by macrophages and translocated to the nucleus and cytoplasm. Additionally, R9-Tat is highly efficient in intracellular protein transport and acts as a protein carrier for carbonic anhydrase to enter cells. Synonyms: H-Gly-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Pro-Pro-Gln-OH; glycyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-prolyl-L-prolyl-L-glutamine. Grades: >95% by HPLC. Molecular formula: C71H135N41O15. Mole weight: 1803.13. | |
R9-TAT Quick inquiry Where to buy Suppliers range | R9-Tat is the arginine-substituted analog for the HIV Tat protein (48-60). Similar to Tat (48-60), R9-Tat is internalized by macrophages and translocated to the nucleus and cytoplasm. Additionally, R9-Tat is efficient in intracellular protein delivery, serving as a protein carrier for Carbonic anhydrase into the cell. Uses: HIV-TAT Family. Product ID: GR1213. | |
S4 Quick inquiry Where to buy Suppliers range | S4 is a high affinity and selective carbonic anhydrase CA IX and CA XII inhibitor (Ki = 2, 7, 547 and 5600 nM for CA XII, IX, II and I, respectively). S4 has been shown to inhibit migration and proliferation of breast cancer cells in in vitro assays. S4 inhibits lung metastasis in mice bearing breast tumor xenografts, without affecting primary tumor. Synonyms: 4-[[[ (3, 5-Dimethylphenyl) amino]carbonyl]amino]phenyl sulfamate; CAIX Inhibitor S4. Grades: ≥99% by HPLC. CAS No. 1330061-67-0. Molecular formula: C15H17N3O4S. Mole weight: 335.38. | |
(S)-4-amino-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide Quick inquiry Where to buy Suppliers range | An impurity of Brinzolamide, a potent carbonic anhydrase inhibitor used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension. CAS No. 2183841-60-1. Molecular formula: C10H17N3O5S3. Mole weight: 355.45. | |
SLC-0111 Quick inquiry Where to buy Suppliers range | SLC-0111, also known as U-104, MST-104 and NSC 213841, is a potent carbonic anhydrase (CA) inhibitor (Ki values are 4.5, 45.1, 5080 and 9640 nM for CA XII, CA IX, CA I and CA II respectively in MDA-MB-231 cells). U-104 associates with CAIX/CAXII only under hypoxic conditions in vivo, reducing extracellular acidity and resulting in significant inhibition of tumor growth and metastasis in experimental models. Synonyms: 4- (3- (4-fluorophenyl) ureido) benzenesulfonamide; SLC-0111; SLC0111; SLC 0111; MST-104; MST-104; MST-104; NSC-213841; NSC213841; NSC 213841; U-104; U104; U 104. CAS No. 178606-66-1. Molecular formula: C13H12FN3O3S. Mole weight: 309.31. | |
Sulfamide Quick inquiry Where to buy Suppliers range | A carbonic anhydrase inhibitor. Group: Biochemicals. Alternative Names: Imidosulfamic Acid; NSC 252; Sulfonyl Diamide; Sulfuric Diamide; Sulfuryl Amide; Sulfuryl Diamide; Sulphamide. Grades: Highly Purified. CAS No. 7803-58-9. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
Sulthiame Quick inquiry Where to buy Suppliers range | Sulthiame is a benzenesulfonamide derivative. Sulthiame acts as an inhibitor of the enzyme carbonic anhydrase. Sulthiame is used as an anticonvulsant in the treatment of benign and symptomatic focal epilepsy. Group: Biochemicals. Alternative Names: 4-(Tetrahydro-1,1-dioxido-2H-1,2-thiazin-2-yl)benzenesulfonamide; 4-(Tetrahydro-2H-1,2-thiazin-2-yl)benzenesulfonamide S,S-Dioxide; 2-(p-Sulfamoylphenyl)-tetrahydro-2H-1,2-thiazine 1,1-Dioxide; A 168; Bayer A 168; Conadil; Contravul; Elisal; Ospolot; Riker 594; Sulphenyltame; Sulphenytame; Sulphthiame; Sulthiam; Sulthiamine; Sultiam; Sultiame; Trolone; p-(Tetrahydro-2H-1,2-thiazin-2-yl)benzenesulfonamide Dioxide. Grades: Highly Purified. CAS No. 61-56-3. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
Tioxolone Quick inquiry Where to buy Suppliers range | Tioxolone is a metalloenzyme carbonic anhydrase I inhibitor with a Ki of 91 nM. Synonyms: 6-Hydroxy-1,3-benzoxathiol-2-one. Grades: >98%. CAS No. 4991-65-5. Molecular formula: C7H4O3S. Mole weight: 168.17. |