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| Product | Description | |
|---|---|---|
| 6-Chloropurine | Astragaloside III has cardioprotective effects as well as causing improvement in cognitive function. Used in the prevention of cardio-cerebral vascular diseases. Antioxidant. Uses: Antiviral agents. Synonyms: 6-Chloro-9H-purine; NSC 744; 6-Chloro-1H-purine. Grades: 95 %. CAS No. 87-42-3. Molecular formula: C5H3ClN4. Mole weight: 154.56. |  |
| 8-[(6-Amino)hexyl]-amino-cGMP - ATTO-680 | 8-[(6-Amino)hexyl]-amino-cGMP - ATTO-680 is a fluorescent labeling molecule used in the biomedical industry for research purposes. It can be used to visualize and track intracellular signaling processes involving cGMP in various cell types, as well as for studying cardiovascular diseases and vascular dysfunction related to nitric oxide (NO) signaling. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with ATTO 680, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H26N7O7P - ATTO 680 (free acid). Mole weight: 966.39 (free acid). | |
| 9-PAHSA | 9-PAHSA is an orally available anti-inflammatory lipid that lowers blood sugar and reduces inflammation. 9-PAHSA also improved carotid vascular calcification and attenuates cardiac hypertrophy and dysfunction in db/db mice. 9-PAHSA increases the viability of steatosis primary mouse hepatocytes (PMH). 9-PAHSA can be used in research on diabetes, inflammation, and cardiovascular disease [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 1481636-31-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120657. |  |
| Adenosine-3',5'-bisphosphate | Adenosine-3',5'-bisphosphate, a pivotal signaling molecule, exerts indispensable influence on various intracellular actions, modulating ATP synthesis and degradation, catalyzing purine metabolism, and regulating RNA expression. Its therapeutic application encompasses a broad range of diseases including but not limited to cardio-cerebral vascular diseases, cancer, and autoimmunity. Emphasizing its outstanding anti-inflammatory effect, this versatile molecule holds great promise in combating a broad spectrum of inflammatory disorders, qualifying itself as an ideal drug candidate. Synonyms: (pAp); Adenosine-3',5'-bisphosphate, Triethylammonium salt. Grades: ≥ 95% by HPLC. CAS No. 1053-73-2. Molecular formula: C10H15N5O10P2 (free acid). Mole weight: 427.20 (free acid). | |
| Blue dextran (MW 2000000) - from Leuconostoc spp | Blue dextran (MW 2000000) from Leuconostoc spp is an intriguing biomaterial that serves as a vital instrument in the realm of biomedical research. This dye-conjugated polysaccharide, renowned for its extensive molecular dimensions, is ubiquitously employed as a discerning gauge and meticulous exploring agent within the realms of molecular weight ascertainment, gel filtration chromatography, and the profound investigation of vascular permeability. The compound is pharmacologically active and could advance drug research into diseases such as cancer, cardiovascular disease and kidney disease. Synonyms: Blue Dextran 5. CAS No. 87915-38-6. Molecular formula: (C6H10O5)n. | |
| Desmosterol | Desmosterol is a cholesterol-like molecule. In the Bloch pathway of cholesterol biosynthesis, Desmosterol is a direct precursor of cholesterol. As an endogenous metabolite, Desmosterol is used to study cholesterol metabolism [1]. Desmosterol is an LXR activator and SREBP inhibitor, which can suppress macrophage inflammasome activation and prevent vascular inflammation and atherosclerosis. A reduction in Desmosterol promotes the production of mitochondrial reactive oxygen species ( ROS ) in macrophages and pyrin domain-dependent inflammasome activation of NLRP3. Desmosterol holds potential for research in inflammation, metabolism, and cardiovascular diseases [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 313-04-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113224. | |
| Griseofulvin | Griseofulvin is an orally active antifungal antibiotic with antitumor activity. Griseofulvin induces apoptosis and G2/M cell cycle arrest in cancer cells. Griseofulvin also has cardiovascular modulatory activity, reducing angina pectoris, relieving hand artery spasm associated with onychomycosis, and peripheral vascular diseases such as shoulder-hand syndrome [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Natural products. CAS No. 126-07-8. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g; 10 g; 25 g. Product ID: HY-17583. | |
| Human serum albumin | Human serum albumin (HSA) is the most abundant protein in plasma and is a major determinant of plasma oncotic pressure. Human serum albumin exhibits antioxidant, anticoagulant, anti-inflammatory, anti-platelet aggregation activities as well as colloid osmotic action. Human serum albumin can block the inhibitory effect of GML on human T cells, providing protective function for T cells. Human serum albumin is also associated with cardiovascular diseases and can partially prevent the LPS (HY-D1056) induced oxidative stress, as well as the upregulation of NF-κB , NF-κB , and peroxynitrite (ONOO - ) in the vascular wall, contributing to the reduction of blood pressure [1] [2] [3]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: HSA. CAS No. 70024-90-7. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 1 mg. Product ID: HY-P1956. | |
| Nicorandil | Nicorandil (SG-75) is a potent potassium channel activator and targets vascular nucleoside diphosphate-dependent K + channels and cardiac ATP-sensitive K + channels (K ATP ). Nicorandil is a nicotinamide ester with vasodilatory and cardioprotective effects and has the potential for angina and forischemic heart diseases [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SG-75. CAS No. 65141-46-0. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B0341. | |
| Pravastatin | Pravastatin is an antilipemic fungal metabolite isolated from cultures of Nocardia autotrophica. It acts as a competitive inhibitor of HMG CoA reductase with IC50 of 5.6 μM. It is used in combination with diet, exercise, and weight loss for lowering cholesterol and preventing cardiovascular disease. It is a synthetic lipid-lowering agent. It lowers plasma cholesterol and lipoprotein levels, and modulates immune responses by suppressing major histocompatibility complex II on interferon gamma-stimulated, antigen-presenting cells such as human vascular endothelial cells. It is primarily used for the treatment of dyslipidemia and the prevention of cardiovascular disease. It is used to reduce LDL cholesterol and triglyceride levels and increase HDL cholesterol in the prevention of cardiovascular disease. Uses: Pravastatin acts as a competitive inhibitor of hmg coa reductase. it is a synthetic lipid-lowering agent. it is primarily used for the treatment of dyslipidemia and the prevention of cardiovascular disease. it is used to reduce ldl cholesterol and triglyceride levels and increase hdl cholesterol in the prevention of cardiovascular disease. Synonyms: 1-Naphthaleneheptanoicacid, 1, 2, 6, 7, 8, 8a-hexahydro-b, d, 6-trihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-, [1S-[1a(bS*, dS*), 2a, 6a, 8b(R*), 8aa]]-; 3b-Hydroxycompactin; Eptastatin; Mevalothin; Pravastatin acid;Pravachol; Pravastatina; Pravastatine; Pravastatinum; (3R, 5R)-7-[(1S, 2S, 6S, 8S, 8aR)-6-hydroxy-2-methyl-8-[(2S)-2-methylbutanoyl]oxy-1, 2, 6, 7, 8, 8a-hexahydronaphthalen-1-yl]-3, 5-dihydroxyheptanoic acid. Grades: 98%. CAS No. 81093-37-0. Molecular formula: C23H36O7. Mole weight: 424.53. | |
| Salvianolic acid B | Salvianolic acid B is an active ingredient of Salvia miltiorrhiza, which has been widely applied in China for the management of various microcirculation-related disorders, such as cardiovascular disease, cerebrovascular disease, and diabetic vascular complication. Uses: Scientific research. Group: Natural products. Alternative Names: Lithospermic acid B. CAS No. 121521-90-2. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-N1362. | |
| Urotensin II (goby) trifluoroacetate salt | Urotensin II is a potent peptide vasoconstrictor and an agonist of the urotensin (UT) receptor. For its distribution in multiple biological systems such as the cardiovascular, nervous, endocrine, and renal, it has been identified as a potential target for therapies of atherosclerosis, heart failure, hypertension, pre-eclampsia, diabetes, renal disease, as well as brain vascular lesions. Synonyms: U-II; Urotensin II (G. mirabilis). Grades: ≥95%. Molecular formula: C62H84N14O17S2·xCF3COOH. Mole weight: 1361.56. | |
| Urotensin II (human) trifluoroacetate salt | Urotensin II is a potent peptide vasoconstrictor and an agonist of the urotensin (UT) receptor. For its distribution in multiple biological systems such as the cardiovascular, nervous, endocrine, and renal, it has been identified as a potential target for therapies of atherosclerosis, heart failure, hypertension, pre-eclampsia, diabetes, renal disease, as well as brain vascular lesions. Synonyms: hU II. Grades: ≥95%. Molecular formula: C64H85N13O18S2·xCF3COOH. Mole weight: 1388.57. | |
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