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| Product | Description | |
|---|---|---|
| 4-Chloro-6-(2-chloro-ethoxy)-7-(2-methoxy-ethoxy)-quinazoline | 4-Chloro-6-(2-chloro-ethoxy)-7-(2-methoxy-ethoxy)-quinazoline. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| 4-Chloro-6-methoxy-quinazoline ≥97% (HPLC) | 4-Chloro-6-methoxy-quinazoline ≥97% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 2.5g. US Biological Life Sciences. | Worldwide |
| 4-Chloro-7-(2-chloro-ethoxy)-6-(2-methoxy-ethoxy)-quinazoline | 4-Chloro-7-(2-chloro-ethoxy)-6-(2-methoxy-ethoxy)-quinazoline. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 6-(Benzyloxy)-4-(3-chloro-4-fluorophenylamino)-7-methoxy-quinazoline | 6-(Benzyloxy)-4-(3-chloro-4-fluorophenylamino)-7-methoxy-quinazoline (CAS# 913819-12-2 ) is a useful research chemical. Synonyms: N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(phenylmethoxy)-4-quinazolinamine. Grades: 95 %. CAS No. 913819-12-2. Molecular formula: C22H17ClFN3O2. Mole weight: 409.84. |  |
| N4-(3-chloro-2-fluorophenyl)-7-methoxy-4,6-quinazolinediamine | One of the impurities of Dacomitinib. Dacomitinib, aslo known as PF-299 and PF-00299804 or PF299804, is an orally bioavailable, highly selective, second-generation small-molecule inhibitor of the pan-epidermal growth factor receptor (EGFR) family of tyrosine kinases (ErbB family) with potential antineoplastic activity. Synonyms: Dacomitinib Impurity 2F3LAJ. Grades: ≥95%. CAS No. 1221892-23-4. Molecular formula: C15H12ClFN4O. Mole weight: 318.73. | |
| N4-(3-Chloro-4-Fluorophenyl)-7-Methoxyquinazoline-4,6-Diamine | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-aminoquinazolin-4-amine; 4,6-Quinazolinediamine, N4-(3-chloro-4-fluorophenyl)-7-methoxy-; Afatinib Impurity JYJ-2. Grades: ≥95%. CAS No. 179552-75-1. Molecular formula: C15H12ClFN4O. Mole weight: 318.73. | |
| Gefitinib Impurity X | Synonyms: 6-Acetoxy-4-chloro-7-methoxyquinazoline; 4-Chloro-6-acetoxy-7-methoxyquinazoline; 4-Chloro-7-methoxy-6-quinazolinol 6-acetate; Gefitinib interMediate V; 6-Quinazolinol, 4-chloro-7-Methoxy-, 6-acetate; N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropox. Grades: > 95%. CAS No. 230955-75-6. Molecular formula: C11H9ClN2O3. Mole weight: 252.66. | |
| Lapatinib 2-Fluoro Impurity | Synonyms: Lapatinib 2-Fluoro Impurity; 3-Desfluoro 2-Fluoro Lapatinib; N- (3-Chloro-4- ( (2-fluorobenzyl) oxy) phenyl) -6- (5- ( ( (2- (methylsulfonyl) ethyl) amino) methyl) furan-2-yl) quinazolin-4-amine; N-[3-chloro-4-[ (2-fluorophenyl) methoxy]phenyl]-6-[5-[ (2-methylsulfonylethylamino) methyl]furan-2-yl]quinazolin-4-amine; N-[3-Chloro-4-[(2-fluorophenyl)methoxy]phenyl]-6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-4-quinazolinamine; SCHEMBL11962955; AUSNUFCAWIGPSG-UHFFFAOYSA-N; N-{3-chloro-4-[ (2-fluorobenzyl) oxy]phenyl}-6-[5- ({[2- (methylsulfonyl) ethyl]amino}methyl) furan-2-yl]quinazoline-4-amine. Grades: > 95%. CAS No. 1393112-45-2. Molecular formula: C29H26ClFN4O4S. Mole weight: 581.07. | |
| N-[3-Chloro-4-[ (3-fluorobenzyl) oxy]phenyl]-6-iodoquinazolin-4-amine | Lapatinib intermediate. Group: Biochemicals. Alternative Names: N-[3-Chloro-4-[ (3-fluorophenyl) methoxy]phenyl]-6-iodo-4-quinazolinamine; 6-Iodo-4-[3-chloro-4- (3-fluorobenzyloxy) anilino]quinazoline. Grades: Highly Purified. CAS No. 231278-20-9. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| O-Desmorpholinopropyl Gefitinib | A metabolite of Gefitinib. Group: Biochemicals. Alternative Names: 4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinol;4-(3-Chloro-4-fluorophenylamino)-6-hydroxy-7-methoxyquinazoline. Grades: Highly Purified. CAS No. 184475-71-6. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| 1-(4-((3-Chloro-4-fluorocyclohexyl)amino)-7-methoxyquinazolin-6-yl)-5-hydroxypyrrolidin-2-one | One of the impurities of Dacomitinib. Dacomitinib, aslo known as PF-299 and PF-00299804 or PF299804, is an orally bioavailable, highly selective, second-generation small-molecule inhibitor of the pan-epidermal growth factor receptor (EGFR) family of tyrosine kinases (ErbB family) with potential antineoplastic activity. Synonyms: 2-Pyrrolidinone, 1-[4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-5-hydroxy-; Dacomitinib Impurity WYQJ. Grades: ≥95%. CAS No. 2190490-31-2. Molecular formula: C19H16ClFN4O3. Mole weight: 402.81. | |
| 3-Desmorpholinyl-3-hydroxyethylamino gefitinib | 3-Desmorpholinyl-3-hydroxyethylamino gefitinib. Group: Biochemicals. Alternative Names: 2- [ [3- [ [4- [ (3-Chloro-4-fluorophenyl) amino] -7-methoxy-6-quinazolinyl] oxy] propyl] amino] ethanol. Grades: Highly Purified. CAS No. 847949-56-8. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C20H22ClFN4O3. US Biological Life Sciences. | Worldwide |
| 3-Desmorpholinyl-3-hydroxyethylamino Gefitinib | 3-Desmorpholinyl-3-hydroxyethylamino Gefitinib is a metabolite of Gefitinib. Synonyms: Ethanol, 2-[[3-[[4-[(3-chloro-4-fluorophenyl)aMino]-7-Methoxy-6-quinazolinyl]oxy]propyl]aMino]-; 2- [ [3- [ [4- [ (3-Chloro-4-fluorophenyl) aMino] -7-Methoxy-6-quinazolinyl] oxy] propyl] aMino] ethanol; Gefitinib iMpurity D; 2-((3-((4-((3-chloro-4-fluorophenyl)amino)-7-. Grades: > 95%. CAS No. 847949-56-8. Molecular formula: C20H22ClFN4O3. Mole weight: 420.87. | |
| 4-Defluoro-4-hydroxy gefitinib | 4-Defluoro-4-hydroxy gefitinib. Group: Biochemicals. Alternative Names: 2-Chloro-4- [ [7-methoxy-6- [3- (4-morpholinyl) propoxy] -4-quinazolinyl] amino] phenol. Grades: Highly Purified. CAS No. 847949-50-2. Pack Sizes: 10mg, 25mg, 50mg, 100mg. Molecular Formula: C22H25ClN4O4. US Biological Life Sciences. | Worldwide |
| 4-Defluoro-4-hydroxy Gefitinib | 4-Defluoro-4-hydroxy Gefitinib is a metabolite of Gefitinib. Synonyms: 2-Chloro-4-[[7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinyl]amino]phenol; Phenol, 2-chloro-4-[[7-Methoxy-6-[3-(4-Morpholinyl)propoxy]-4-quinazolinyl]aMino]-; 2-Chloro-4-[[7-Methoxy-6-[3-(4-Morpholinyl)propoxy]-4-quinazolinyl]aMino]phenol; Gefitinib iM. Grades: > 95%. CAS No. 847949-50-2. Molecular formula: C22H25ClN4O4. Mole weight: 444.92. | |
| 5-[4-[[3-Chloro-4-[ (3-fluorophenyl) methoxy]phenyl]amino]-6-quinazolinyl]-2-furancarboxaldehyde | Lapatinib intermediate. Group: Biochemicals. Alternative Names: [5-[4-[4-[(3-Fluorobenzyl)oxy]-3-chloroanilino]-6-quinazolinyl]-2-furancarboxaldehyde. Grades: Highly Purified. CAS No. 231278-84-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Afatinib Impurity 5 | An analogue of Afatinib. Synonyms: 4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)?-7-methoxy-6-nitro-. Grades: > 95%. CAS No. 179552-74-0. Molecular formula: C15H10ClFN4O3. Mole weight: 348.72. | |
| AST-1306 | AST-1306 is a selective irreversible inhibitor of the epidermal growth factor receptor (EGFR) 1 and 2. Studies show that AST-1306 inhibited the enzymatic activities of wild-type EGF) and ErbB2 as well as EGFR resistant mutant in both cell-free and cell-based systems. AST-1306 was more effective in inhibiting tumors with ErbB2-overexpressing cells than EGFR-overexpressing tumor. Group: Biochemicals. Alternative Names: N- [4- [ [3-Chloro-4- [ (3-fluorobenzyl) oxy] phenyl] amino] quinazolin-6-yl] acrylamide; N-[4-[[3-Chloro-4-[ (3-fluorophenyl) methoxy]phenyl]amino]-6-quinazolinyl]-2-propenamide; ALS1306; AST 1306; AST 6. Grades: Highly Purified. CAS No. 897383-62-9. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Epertinib | Epertinib, also known as S-222611, is a potent, oral, reversible, and selective tyrosine kinase inhibitor of EGFR, HER2 and HER4, with IC50s of 1.48 nM, 7.15 nM and 2.49 nM, respectively, currently under trials in patients with solid tumours. It also inhibited intracellular kinase activity and the growth of EGFR-expressing and HER2-expressing cancer cells. Synonyms: Epertinib; S-22611; S22611; S 22611; (R, Z) -1- (4- ( (3-chloro-4- ( (3-fluorobenzyl) oxy) phenyl) amino) quinazolin-6-yl) but-2-yn-1-one O-morpholin-3-ylmethyl oxime; Epertinib; S-222611; S222611; S 222611; 2-Butyn-1-one, 1-(4-((3-chloro-4-((3-fluorophenyl)methoxy)phenyl)amino)-6-quinazolinyl)-, O-((3R)-3-morpholinylmethyl)oxime, (1Z)-; N-{3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl}- 6-[(1Z)-N-{[(3R)-morpholin-3-yl]methoxy}but- 2-ynimidoyl]quinazolin-4-amine. CAS No. 908305-13-5. Molecular formula: C30H27ClFN5O3. Mole weight: 559.178. | |
| GDC6036 | GDC-6036, also known as RG6330, is an orally bioavailable, highly potent and selective KRAS G12C inhibitor, with a median IC50 in the sub-nanomolar range and greater than 18,000-fold selectivity for G12C versus non-G12C cell lines. GDC-6036 demonstrates greater potency and selectivity compared with other KRAS G12C inhibitors in vitro, and complete tumor growth inhibition in multiple KRAS G12C-positive cell lines and in xenograft mouse models. We will highlight the research program that led to the discovery and optimization of GDC-6036, which is currently in clinical development. Group: Inhibitors. Alternative Names: GDC-6036; GDC 6036; GDC6036; RG6330; RG-6330; RG 6330. CAS No. 2417987-45-0. Molecular formula: C29H32ClF4N7O2. Mole weight: 622.07. Appearance: To be determined. Purity: >98%. IUPACName: 1-((S)-4-(7-((R)-6-amino-4-methyl-3-(trifluoromethyl)pyridin-2-yl)-6-chloro-8-fluoro-2-(((S)-1-methylpyrrolidin-2-yl)methoxy)quinazolin-4-yl)-3-methylpiperazin-1-yl)prop-2-en-1-one. Canonical SMILES: NC1=N[C@] ([C@]2=C (C=C3C (N=C (N=C3N4[C@H] (CN (CC4)C (C=C)=O)C)OC[C@H]5N (CCC5)C)=C2F)Cl)=C (C (C)=C1)C (F) (F)F. Catalog: ACM2417987450. |  |
| Gefitinib-d3 | Labeled Gefitinib. Gefitinib is an antineoplastic. Group: Biochemicals. Alternative Names: N-(3-Chloro-4-fluorophenyl)-7-(methoxy-d3)-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine; Iressa-d3; ZD 1839-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Gefitinib impurity 29 | Gefitinib impurity 29. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine. CAS No. 184475-35-2. Molecular Formula: C22H24ClFN4O3. Mole Weight: 446.9. Catalog: APB184475352. |  |
| Gefitinib Impurity P | Gefitinib Impurity P. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)-N-(3-morpholinopropyl)quinazolin-4-amine. CAS No. 1502829-45-9. Molecular Formula: C29H37ClFN5O4. Mole Weight: 574.09. Catalog: APB1502829459. | |
| Gefitinib Impurity VIII | Synonyms: 4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinol 6-acetate; 4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yl acetate; 6-Quinazolinol,4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-, 6-acetate; Gefitinib intermediate VI. Grades: > 95%. CAS No. 788136-89-0. Molecular formula: C17H13ClFN3O3. Mole weight: 361.76. | |
| Gefitinib N-Oxide | Gefitinib N-oxide is the N-oxide derivative of Gefitinib. Synonyms: Gefitinib Morpholine N-oxide; N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-oxido-4-morpholinyl)propoxy]-4-quinazolinamine; 4-(3-((4-((3-chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)propyl)morpholine 4-oxide. Grades: > 95%. CAS No. 847949-51-3. Molecular formula: C22H24ClFN4O4. Mole weight: 462.91. | |
| GW 583340 dihydrochloride | GW 583340 dihydrochloride is a potent dual EGFR/ErbB2 tyrosine kinase inhibitor (IC50 = 0.01 and 0.014 μM, respectively). GW 583340 selectively inhibits growth of human tumor cells overexpressing EGFR and ErbB2 (IC50 = 0.11 μM for inhibition of HN5, N87 and BT474 tumor cell lines vs. > 30 μM for inhibition of non-tumor cell line HFF). it is used in the treatment of breast cancer. Synonyms: GW 583340 dihydrochloride; GW-583340 dihydrochloride; GW583340 dihydrochloride; N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[2-[[[2-(methylsulfonyl)ethyl]amino]methyl]-4-thiazolyl]-4-quinazolinamine dihydrochloride. Grades: ≥97% by HPLC. CAS No. 1173023-85-2. Molecular formula: C28H25ClFN5O3S2.2HCl. Mole weight: 671.03. | |
| Lapatinib-13C2,15N | Labeled Lapatinib. Reversible dual inhibitor of ErbB1 and ErbB2 tyrosine kinases. Antineoplastic. Group: Biochemicals. Alternative Names: N-[3-Chloro-4-[ (3-fluorophenyl) methoxy]phenyl]-6-[5-[[[2- (methylsulfonyl) ethyl]amino]methyl]-2-furanyl]-4-quinazolinamine-13C2, 15N; GSK 572016-13C2,15N; GW 572016-13C2,15N; GW 572016X-13C2,15N. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| Lapatinib-13C2,15N Ditosylate | Labeled Lapatinib. Reversible dual inhibitor of ErbB1 and ErbB2 tyrosine kinases. Antineoplastic. Group: Biochemicals. Alternative Names: N-[3-Chloro-4-[ (3-fluorophenyl) methoxy]phenyl]-6-[5-[[[2- (methylsulfonyl) ethyl]amino]methyl]-2-furanyl]-4-quinazolinamine Bis (4-methyl Benzene sulfonate) -13C2, 15N Ditosylate; GW-572016F-13C2,15N; Tykerb-13C2,15N Ditosylate. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| Lapatinib-d7 ditosylate | Heterocyclic Organic Compound. Alternative Names: N-[3-Chloro-4-[ (3-fluorophenyl) methoxy]phenyl]-6-[5-[[[2- (methylsulfonyl) ethyl-d7]amino]methyl]-2-furanyl]-4-quinazolinamine Bis(4-methylbenzenesulfonate) Ditosylate; GW-572016F-d7 Ditosylate; Tykerb-d7 Ditosylate. CAS No. 1009307-24-7. Molecular formula: C43H35D7ClFN4O10S3. Mole weight: 932.5. Purity: 0.96. IUPACName: N-[3-chloro-4-[ (3-fluorophenyl) methoxy]phenyl]-6-[5-[[[1, 1, 2, 2-tetradeuterio-2- (trideuteriomethylsulfonyl) ethyl]amino]methyl]furan-2-yl]quinazolin-4-amine; 4-methylbenzenesulfonic acid. Canonical SMILES: CC1=CC=C (C=C1)S (=O) (=O)O. CS (=O) (=O)CCNCC1=CC=C (O1)C2=CC3=C (C=C2)N=CN=C3NC4=CC (=C (C=C4)OCC5=CC (=CC=C5)F)Cl. Catalog: ACM1009307247. | |
| Lapatinib Ditosylate | Reversible dual inhibitor of ErbB1 and ErbB2 tyrosine kinases. Antineoplastic. Group: Biochemicals. Alternative Names: N-[3-Chloro-4-[ (3-fluorophenyl) methoxy]phenyl]-6-[5-[[[2- (methylsulfonyl) ethyl]amino]methyl]-2-furanyl]-4-quinazolinamine Bis (4-methyl Benzene sulfonate) Ditosylate; GW-572016F Ditosylate; Tykerb Ditosylate. Grades: Highly Purified. CAS No. 388082-77-7. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Lapatinib, Free Base | ATP-competitive EGFR & ErbB-2 dual tyrosine kinase inhibitor. Lapatinib is an ATP-competitive epidermal growth factor receptor (EGFR) and HER2/neu (ErbB-2) dual tyrosine kinase inhibitor, with IC(50) values of 10.8 and 9.2nm respectively. It is an orally active drug for treatment of breast cancer and other solid tumors. A free base form of Lapatinib Ditosylate. Lapatinib (as the di-p-toluenesulfonate salt) is the active ingredient in the drug sold under the trade names Tykerb in the US and Tyverb in Europe. This drug has been approved in at least one country to treat advanced metastatic breast cancer in conjunction with the chemotherapy drug Xeloda (generic name, capecitabine). Group: Biochemicals. Alternative Names: N-[3-Chloro-4-[ (3-fluorophenyl) methoxy]phenyl]-6-[5-[[[2- (methylsulfonyl) ethyl]amino]methyl]-2-furanyl]-4-quinazolinamine, GSK 572016, GW-572016, GW 572016X, Tykerb, Tyverb. Grades: Highly Purified. CAS No. 231277-92-2. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Lapatinib Hydroxylamine | a complex used in human metabolism of lapatinib which is a dual kinase inhibitor. Synonyms: N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[[hydroxy[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-4-quinazolinamine. Grades: > 95%. CAS No. 1360431-86-2. Molecular formula: C29H26ClFN4O5S. Mole weight: 597.07. | |
| Lapatinib Impurity 10 | Synonyms: UNII-2T859UZJ2V; Lapatinib IMpurity 10; 1152131-73-1; Lapatinib metabolite M12; 2T859UZJ2V; 5- (4- ( (3-Chloro-4- ( (3-fluorobenzyl) oxy) phenyl) amino) quinazolin-6-yl) furan-2-carboxylic acid; 2-Furancarboxylic acid, 5-(4-((3-chloro-4-((3-fluorophenyl)methoxy)phenyl)amino)-6-quinazolinyl)-; 5-(4-((3-Chloro-4-((3-fluorophenyl)methoxy)phenyl)amino)-6-quinazolinyl)-2-furancarboxylic acid; 5-[4-[3-chloro-4-[ (3-fluorophenyl) methoxy]anilino]quinazolin-6-yl]furan-2-carboxylic acid; SCHEMBL3713537; CHEMBL3526263; ALLDUFLYKPDTCS-UHFFFAOYSA-N; N-(3-chloro-4-((3-fluorobenzyl)oxy)phenyl)-6-(5-carboxy-2-furyl)-4-quinazolinamine. Grades: > 95%. CAS No. 1152131-73-1. Molecular formula: C26H17ClFN3O4. Mole weight: 489.89. | |
| Lapatinib Impurity 3 | A reactive metabolite of Lapatinib. Synonyms: N-De[2-(methylsulfonyl)ethyl] Lapatinib; 6-[5-(Aminomethyl)-2-furanyl]-N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-4-quinazolinamine. Grades: > 95%. CAS No. 697299-82-4. Molecular formula: C26H20ClFN4O2. Mole weight: 474.93. | |
| Lapatinib Impurity 8 | A reactive metabolite of Lapatinib. Synonyms: 6-[5-(hydroxymethyl)-2-furanyl]-N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-4-quinazolinamine. Grades: > 95%. Molecular formula: C26H19ClFN3O3. Mole weight: 475.91. | |
| MS39 | MS39 (compound 6) is a PROTAC targeting EGFR. MS39 is composed of PROTAC target protein ligand N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(3-(piperazin-1-yl)propoxy)quinazolin-4-amine (HY-W109039) (red part), E3 ligase ligand (S,R,S)-AHPC (HY-125845) (blue part) and PROTAC Linker Undecanedioic acid (HY-W014125) (black part), among which the conjugate of E3 ubiquitin ligase ligand + Linker is (S,R,S)-AHPC-CO-C9-acid (HY-139345). MS39 reduces the expression of EGFR and downstream signaling in HCC-827 and H3255 cells. MS39 inhibits the proliferation of H3255 cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2675490-92-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-157581. |  |
| N-(3-chloro-2-fluorophenyl)-7-methoxy-6-nitro-4-Quinazolinamine | One of the impurities of Dacomitinib. Dacomitinib, aslo known as PF-299 and PF-00299804 or PF299804, is an orally bioavailable, highly selective, second-generation small-molecule inhibitor of the pan-epidermal growth factor receptor (EGFR) family of tyrosine kinases (ErbB family) with potential antineoplastic activity. Synonyms: Dacomitinib Impurity 2F3LXJ. Grades: ≥95%. CAS No. 1454307-45-9. Molecular formula: C15H10ClFN4O3. Mole weight: 348.72. | |
| N-[3-Chloro-4-[ (3-fluorophenyl) methoxy]phenyl]-6-[5-[[2- ( (1-Oxyl-2, 2, 5, 5-tetramethylpyrroline-3-yl) carbamido) ethyl]amino]methyl]-2-furanyl]-4-quinazolinamine | N-[3-Chloro-4-[ (3-fluorophenyl) methoxy]phenyl]-6-[5-[[2- ( (1-Oxyl-2, 2, 5, 5-tetramethylpyrroline-3-yl) carbamido) ethyl]amino]methyl]-2-furanyl]-4-quinazolinamine. Group: Biochemicals. Alternative Names: Demethylsulfonyl Lapatinib 1-Oxyl-2,2,5,5-tetramethyl-Æ3-pyrroline deriv. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C37H37ClFN6O4, Molecular Weight: 684.18. US Biological Life Sciences. | Worldwide |
| N-De[2-(methylsulfonyl)ethyl] lapatinib | N-De[2-(methylsulfonyl)ethyl] lapatinib. Group: Biochemicals. Alternative Names: 6-[5- (Aminomethyl) -2-furanyl]-N-[3-chloro-4-[ (3-fluorophenyl) methoxy]phenyl]-4-quinazolinamine; [6- (5-Aminomethylfuran-2-yl) quinazolin-4-yl][3-chloro-4- (3-fluorobenzyloxy) phenyl]amine. Grades: Highly Purified. CAS No. 697299-82-4. Pack Sizes: 2mg, 5mg, 10mg. Molecular Formula: C26H20ClFN4O2. US Biological Life Sciences. | Worldwide |
| PF 6274484 | PF 6274484 is a high affinity and potent covalent EGFR kinase inhibitor (Ki = 0.14 nM). It inhibits the autophosphorylation of wild-type EGFR in A549 cells and EGFRL858R/T790M in H1975 cells (IC50s = 5.8 and 6.6 nM, respectively). Synonyms: PF 6274484; PF6274484; PF-6274484; N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-2-propenamide. Grades: ≥98% by HPLC. CAS No. 1035638-91-5. Molecular formula: C18H14ClFN4O2. Mole weight: 372.78. | |
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