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Cholecystokinin Cholecystokinin is a peptide hormone. Cholecystokinin, as a hunger suppressant, inhibits food intake and stimulates the digestion of fat and protein. Cholecystokinin can be used for the research of gastrointestinal system [1] [2] [3]. Uses: Scientific research. Group: Peptides. Alternative Names: Cholecystokinin-33(human); CCK-33(human). CAS No. 9011-97-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P2932. MedChemExpress MCE
Cholecystokinin (26-33) (free acid) Cholecystokinin (26-33) (CCK (26-33)) free acid is a cholecystokinin (CCK) fragment. Cholecystokinin (26-33) free acid can reduce food intake and gallbladder contraction [1]. Uses: Scientific research. Group: Peptides. Alternative Names: CCK (26-33) (free acid). CAS No. 103974-46-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3651. MedChemExpress MCE
Cholecystokinin-33 (human) Cholecystokinin-33 (human) is a peptide hormone, holding great significance in biomedical research as it enables exploration into the intricacies of cholecystokinin receptors. Synonyms: CCK-39 (7-39) (human); H-Lys-Ala-Pro-Ser-Gly-Arg-Met-Ser-Ile-Val-Lys-Asn-Leu-Gln-Asn-Leu-Asp-Pro-Ser-His-Arg-Ile-Ser-Asp-Arg-Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2; L-lysyl-L-alanyl-L-prolyl-L-seryl-glycyl-L-arginyl-L-methionyl-L-seryl-L-isoleucyl-L-valyl-L-lysyl-L-asparagyl-L-leucyl-L-glutaminyl-L-asparagyl-L-leucyl-L-alpha-aspartyl-L-prolyl-L-seryl-L-histidyl-L-arginyl-L-isoleucyl-L-seryl-L-alpha-aspartyl-L-arginyl-L-alpha-aspartyl-O4-sulfo-L-tyrosyl-L-methionyl-glycyl-L-tryptophyl-L-methionyl-L-alpha-aspartyl-L-phenylalaninamide. Grade: ≥90%. CAS No. 96827-04-2. Molecular formula: C167H263N51O52S4. Mole weight: 3945.44. BOC Sciences
Cholecystokinin (CCK) Fragment 26-33 Amide, Non-sulfated ?95% (HPLC), powder. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
Cholecystokinin Fragment 30-33 Amide ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 2
Cholecystokinin Precursor (24-32) (rat) Cholecystokinin Precursor (24-32) (rat) is a cholecystokinin precursor that can be expressed in the heart, lungs, and kidneys as well as in the gastrointestinal tract and brain. Cholecystokinin is a brain-gut peptide that stimulates gallbladder contraction and pancreatic exocrine secretion and also acts as a neurotransmitter [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Prepro CCK Fragment V-9-M. CAS No. 99291-20-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P2636. MedChemExpress MCE
Cholecystokinin Precursor Fragment 107-115 Desulfated human >97% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
Anti-Cholecystokinin (26-33) (CCK-8) antibody produced in rabbit whole antiserum. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
(Tyr[SO3H]27)Cholecystokinin fragment 26-33 Amide ?97% (HPLC), powder. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
1,4-Dithio-DL-threitol Reagent for the quantitative reduction of disulfide group. Prevents the oxidation of cholecystokinin during its extraction from brain and duodenal tissues. Cleavage of disulfide bonds in proteins. Uses: Used as a reagent in biochemistry to prevent oxidation of thiol groups and to reduce disulfides to dithiols; has been used as a radioprotectant; dithiothreitol (dtt) is the common name for a small-molecule redox reagent known as cleland's reagent. Synonyms: DL-1,4-Dithiothreitol; DTT; Cleland's reagent; threo-1,4-Dimercapto-2,3-butanediol; Dithiothreitol; dl-Dithiothreitol; 1,4-Dithiothreitol; D-Dtt; 1,4-Dithio-dl-threitol; DL-Dithiothreitol; threo-1,4-Dimercapto-2,3-butanediol. Grade: ≥ 99 % (Assay by titration). CAS No. 3483-12-3. Molecular formula: C4H10O2S2. Mole weight: 154.25. BOC Sciences 8
[2-[[3-(2-Chlorobenzoyl)-5-ethyl-2-thienyl]amino]-2-oxoethyl]carbamic Acid Benzyl Ester Used in the preparation of Clotiazepam (C587410) and thienylamide derivatives as cholecystokinin inhibitors. Group: Biochemicals. Alternative Names: [2-[[3-(2-Chlorobenzoyl)-5-ethyl-2-thienyl]amino]-2-oxoethyl]carbamic Acid Phenylmethyl Ester. Grades: Highly Purified. CAS No. 50508-73-1. Pack Sizes: 100mg. US Biological Life Sciences. USBiological 3
Worldwide
2-Amino-3-(2-chlorobenzoyl)-5-ethylthiophene Used in the preparation of thienylamide derivatives as cholecystokinin inhibitors. Group: Biochemicals. Alternative Names: 2-Amino-3-(o-chlorobenzoyl)-5-ethylthiophene; 2-Amino-5-ethyl-3- (2-chlorobenzoyl) thiophene; (2-Amino-5-ethyl-3-thienyl)(2-chlorophenyl)-methanone. Grades: Highly Purified. CAS No. 50508-60-6. Pack Sizes: 250mg. US Biological Life Sciences. USBiological 3
Worldwide
(2S,4R)-Methyl-4-hydroxypiperidine-2-carboxylate (2S,4R)-Methyl-4-hydroxypiperidine-2-carboxylate has been used as a reactant for the preparation of cholecystokinin B (CCK-B) antagonists. Group: Biochemicals. Grades: Highly Purified. CAS No. 211058-80-9. Pack Sizes: 10mg, 100mg. Molecular Formula: C7H13NO3, Molecular Weight: 159.18. US Biological Life Sciences. USBiological 10
Worldwide
Acetyl-asp-tyr[so3h]-met-gly-trp-met-nh2 Acetyl-asp-tyr[so3h]-met-gly-trp-met-nh2. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Acetyl-[Tyr(SO3H)27]-Cholecystokinin fragment 26-31 Amide, AC1N5SK8, C2795_SIGMA, 3-acetamido-4-[[1-[[1-[[2-[[1-[(1-amino-4-methylsulfanyl-1-oxobutan-2-yl)amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-1-oxo-3-(4-sulfooxyphenyl)propan-2-yl]amino]-4-oxobutanoic acid, 89911-65-9. Product Category: Heterocyclic Organic Compound. CAS No. 89911-65-9. Molecular formula: C38H50N8O13S3. Mole weight: 923.04. Purity: 0.96. IUPACName: 3-acetamido-4-[[1-[[1-[[2-[[1-[(1-amino-4-methylsulfanyl-1-oxobutan-2-yl)amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-1-oxo-3-(4-sulfooxyphenyl)propan-2-yl]amino]-4-oxobutanoic acid. Canonical SMILES: CC(=O)NC(CC(=O)O)C(=O)NC(CC1=CC=C(C=C1)OS(=O)(=O)O)C(=O)NC(CCSC)C(=O)NCC(=O)NC(CC2=CNC3=CC=CC=C32)C(=O)NC(CCSC)C(=O)N. Product ID: ACM89911659. Alfa Chemistry — ISO 9001:2015 Certified. Categories: CCK (26-31) (sulfated). Alfa Chemistry. 3
Asperlicin Asperlicin is a non-peptide cholecystokinin (Cholecystokinin, CCK) produced by Aspergillus alliaceus. It has the effect of antagonizing CCK. A and its derivatives are promising for the treatment of ulcers and pancreatic tumors. Synonyms: Asperlicin A. CAS No. 93413-04-8. Molecular formula: C31H29N5O4. Mole weight: 535.59. BOC Sciences 12
Benzotript Benzotript, an anti-ulcer and anti-gastric drug, is a cholecystokinin receptor (CCK-2R) antagonist and gastrin receptor antagonist that has antiproliferative effects on human colon cancer cell lines. Synonyms: L-Tryptophan, N-(4-chlorobenzoyl)-; N-(4-Chlorobenzoyl)-L-tryptophan; (2S)-2-[(4-Chlorophenyl)formamido]-3-(1H-indol-3-yl)propanoic acid; CR 501; CR 501 (amino acid); N-p-Chlorobenzoyl-L-tryptophan; (4-chlorobenzoyl)-L-tryptophan; (S)-α-(4-Chlorobenzoylamino)-1H-indole-3-propionic acid; Nα-(4-Chlorobenzoyl)-L-tryptophan; Benzotriptum. Grade: ≥95%. CAS No. 39544-74-6. Molecular formula: C18H15ClN2O3. Mole weight: 342.78. BOC Sciences 6
Boc-Trp-Met-Asp-Phe-NH2 Boc-Trp-Met-Asp-Phe-NH2 refers to Tetragastrin, which has been modified with a BOC (tert-Butyloxycarbonyl) group. The BOC group is a commonly used amino protecting group in organic synthesis, especially in peptide synthesis. Tetragastrin itself is the C-terminal tetrapeptide of gastrin, with the sequence H-Trp-Met-Asp-Phe-NH2. Tetragastrin stimulates gastric secretion and acts as a Cholecystokinin (CCK-4) receptor agonist. It is known for its gastric mucosal protective effects and is used to improve symptoms of hypochlorhydria or gastric atony, as well as in the treatment of atrophic gastritis. Synonyms: BOC-Tetragastrin; 4-7-Cholecystokinin-7 (swine), N-[(1,1-dimethylethoxy)carbonyl]-; Alaninamide, N-carboxy-L-tryptophyl-L-methionyl-L-aspartylphenyl-, N-tert-butyl ester, L-; N-[(1,1-Dimethylethoxy)carbonyl]-L-tryptophyl-L-methionyl-L-α-aspartyl-L-phenylalaninamide; (tert-Butoxycarbonyl)tetragastrin; Boc-CCK-4; Boc-WMDF-NH2; N-tert-Butoxycarbonyl-L-tryptophyl-L-methionyl-L-alpha-aspartyl-L-phenylalaninamide. Grade: ≥95%. CAS No. 5235-21-2. Molecular formula: C34H44N6O8S. Mole weight: 696.81. BOC Sciences 6
CCK (26-30) (sulfated) Cholecystokinin (CCK) is a neuropeptide and gut hormone that regulates pancreatic enzyme secretion and gastrointestinal motility, and acts as a satiety signal. CCK (26-30) is an N-terminal fragment of CCK, the sulfated form of CCK (26-30) inhibits binding of [125I]CCK-33 to guinea pig cortical membranes by 10% at 0.1 mM. Synonyms: N-Acetyl cholecystokinin (26-30) (sulfated). Grade: ≥95%. CAS No. 89911-69-3. Molecular formula: C33H41N7O12S2. Mole weight: 791.85. BOC Sciences 6
CCK (26-31) (sulfated) Cholecystokinin (CCK) is a neuropeptide and gut hormone that regulates pancreatic enzyme secretion and gastrointestinal motility, and acts as a satiety signal. CCK (26-31) is an N-terminal fragment of CCK, the sulfated form of CCK (26-31) inhibits binding of [125I]CCK-33 to guinea pig cortical membranes by 21% at 0.1 mM. Synonyms: N-Acetyl cholecystokinin (26-31) (sulfated). Grade: ≥95%. CAS No. 89911-65-9. Molecular formula: C38H50N8O13S3. Mole weight: 923.05. BOC Sciences 6
CCK (27-33) (non-sulfated) Cholecystokinin (CCK) is a neuropeptide and gut hormone that regulates pancreatic enzyme secretion and gastrointestinal motility, and acts as a satiety signal. CCK (27-33) is a C-terminal fragment of CCK. Non-sulfated CCK (27-33) inhibits binding of [3H]naloxone in rat cerebellum membranes with IC50 of 4 μM and inhibits electrically-stimulated contraction of isolated guinea pig ileum with IC50 of 17 μM. Synonyms: Cholecystokinin (27-33) (non-sulfated). Grade: ≥95%. CAS No. 47910-79-2. Molecular formula: C45H57N9O10S2. Mole weight: 948.12. BOC Sciences 6
CCK-4 Acetate Tetragastrin is a tetrapeptide. Synonyms: CCK-4; CCK4; CCK 4; Gastrin Tetrapeptide; Cholecystokinin Octapeptide (5-8); Cholecystokinin Tetrapeptide; Gastrin (14-17) (human). CAS No. 35144-91-3. Molecular formula: C29H36N6O6S. Mole weight: 596.70. BOC Sciences 10
CCK-A receptor inhibitor 1 CCK-A receptor inhibitor 1 is an inhibitor of cholecystokinin A (CCK-A) receptor with a binging IC50 of 340 nM. Synonyms: Pentanoic acid, 5-[(3-methoxypropyl)pentylamino]-4-[(2-naphthalenylsulfonyl)methyl]-5-oxo-; 5-[(3-Methoxypropyl)(pentyl)amino]-4-[(2-naphthylsulfonyl)methyl]-5-oxopentanoic acid. Grade: ≥95%. CAS No. 137004-80-9. Molecular formula: C25H35NO6S. Mole weight: 477.61. BOC Sciences 6
CCK-B Receptor Antagonist 1 CCK-B Receptor Antagonist 1 is a cholecystokinin B (CCK-B) receptor antagonist with the potential to reduce gastric acid secretion. Synonyms: Urea, N-[1-(3,3-dimethyl-2-oxobutyl)-2,3-dihydro-2-oxo-5-(2-pyridinyl)-1H-1,4-benzodiazepin-3-yl]-N'-[3-(methylamino)phenyl]-; 1-[1-(3,3-Dimethyl-2-oxobutyl)-2-oxo-5-(2-pyridinyl)-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-3-[3-(methylamino)phenyl]urea. Grade: ≥99%. CAS No. 168161-71-5. Molecular formula: C28H30N6O3. Mole weight: 498.58. BOC Sciences 6
CCK Octapeptide (non-sulfated) Cholecystokinin (CCK) is a neuropeptide and gut hormone that regulates pancreatic enzyme secretion and gastrointestinal motility, and acts as a satiety signal. CCK Octapeptide (non-sulfated) is the non-sulfated form of the C-terminal octapeptide of CCK. Synonyms: CCK-8 (desulfated); Cholecystokinin (CCK) (26-33); 2-desulfo-cholecystokinin-8 (swine). Grade: 98%. CAS No. 25679-24-7. Molecular formula: C49H62N10O13S2. Mole weight: 1063. BOC Sciences
CCK Octapeptide, non-sulfated acetate Cholecystokinin (CCK) is a neuropeptide and gut hormone that regulates pancreatic enzyme secretion and gastrointestinal motility, and acts as a satiety signal. CCK Octapeptide (non-sulfated) is the non-sulfated form of the C-terminal octapeptide of CCK. Synonyms: CCK-8 (desulfated) acetate; Cholecystokinin (CCK) (26-33) acetate. Molecular formula: C51H66N10O15S2. Mole weight: 1123.26. BOC Sciences 6
CE-326597 CE-326597 is a selective type 1 cholecystokinin receptor (CCK1R)agonist. In Mar 2009, Phase-II for Obesity in World was discontinued. Uses: Obesity. Synonyms: CE-326597; CE326597; CE 326597. (S)-2-(4-((1H-indol-3-yl)methyl)-5-oxo-1-phenyl-4,5-dihydro-6H-benzo[b][1,2,4]triazolo[4,3-d][1,4]diazepin-6-yl)-N-benzyl-N-isopropylacetamide. Grade: 98%. CAS No. 870615-40-0. Molecular formula: C37-H34-N6-O2. Mole weight: 594.72. BOC Sciences 6
Ceruletide Ceruletide is a decapeptide and a potent cholecystokinin receptor agonist. Ceruletide is a safe and effective cholecystokinetic agent with a direct spasmogenic effect on the gallbladder muscle and bile ducts [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Caerulein; Cerulein; FI-6934. CAS No. 17650-98-5. Pack Sizes: 100 μg; 500 μg; 1 mg; 5 mg. Product ID: HY-A0190. MedChemExpress MCE
CHEMBL333994 CHEMBL333994 is a potent and orally active antagonist of cholecystokinin A (CCK-A), with an IC50 of 0.67 nM. Synonyms: FK-480; N-[(3R)-1-(2-Fluorophenyl)-4-oxo-3,4,6,7-tetrahydro[1,4]diazepino[6,7,1-hi]indol-3-yl]-1H-indole-2-carboxamide; 1H-Indole-2-carboxamide, N-[(3R)-1-(2-fluorophenyl)-3,4,6,7-tetrahydro-4-oxo[1,4]diazepino[6,7,1-hi]indol-3-yl]-. Grade: ≥95%. CAS No. 167820-10-2. Molecular formula: C26H19FN4O2. Mole weight: 438.45. BOC Sciences 6
Devazepide Devazepide is a potent and orally active cholecystokinin A(CCK-A) receptor antagonist with IC50 value of 0.26 nM. It is a derivative of benzodiazepine that displays appetite-stimulant effects. It blocks the anorectic response to CCK-8 and increases food intake in rats. It increases appetite and accelerates gastric emptying. It is used as a potential treatment for a variety of gastrointestinal problems including gastroparesis, dyspepsia and gastric reflux. It was developed by Merck Sharp & Dohme and was terminated in clinic phase 2 trials. Uses: Devazepide is used as a potential treatment for a variety of gastrointestinal problems including gastroparesis, dyspepsia and gastric reflux. Synonyms: (3S)-1-Methyl-3-[(1H-indol-2-yl)carbonylamino]-5-phenyl-1H-1,4-benzodiazepin-2(3H)-one; L-364718; MK-329; (S)-N-(2,3-Dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)indole-2-carboxamide; MK-329; MK329; N-[(3S)-1-methyl-2-oxo-5-phenyl-3H-1,4-benzodiazepin-3-yl]-1H-indole-2-carboxamide. Grade: >99 %. CAS No. 103420-77-5. Molecular formula: C25H20N4O2. Mole weight: 408.45. BOC Sciences 7
Devazepide Devazepide (L-364,718) is a potent, competitive, selective and orally active nonpeptide antagonist of cholecystokinin (CCK) receptor , with IC 50 s of 81 pM, 45 pM and 245 nM for rat pancreatic, bovine gallbladder and guinea pig brain CCK receptors, respectively. Devazepide (L-364,718) is effective for gastrointestinal disorders [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: L-364,718; MK-329. CAS No. 103420-77-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106301. MedChemExpress MCE
Dexloxiglumide Dexloxiglumide, an active enantiomer of Loxiglumide, is a selective cholecystokinin type A (CCKA) receptor antagonist. Dexloxiglumide inhibits smooth muscle cell contractions induced by cholecystokinin-octapeptide (CCK-8). Synonyms: Dexloxiglumida; Dexloxiglumidum; CR-2017; (R)-4-(3,4-Dichlorobenzamido)-5-((3-methoxypropyl)(pentyl)amino)-5-oxopentanoic acid. Grade: 95%. CAS No. 119817-90-2. Molecular formula: C21H30Cl2N2O5. Mole weight: 461.38. BOC Sciences 7
Dexloxiglumide Dexloxiglumide is a selective cholecystokinin type A (CCKA) receptor antagonist [1]. Dexloxiglumide, the active enantiomer of Loxiglumide, inhibits smooth muscle cell contractions induced by cholecystokinin-octapeptide (CCK-8) [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 119817-90-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128878. MedChemExpress MCE
Gastrin I, human Gastrin I, human is the endogenous peptide produced in the stomach, and increases gastric acid secretion via cholecystokinin 2 (CCK2) receptor. Uses: Scientific research. Group: Peptides. CAS No. 10047-33-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1097. MedChemExpress MCE
H-ASP-TYR-OH H-ASP-TYR-OH. Synonyms: Asp-tyr; Aspartyltyrosine; Cholecystokinin Octapeptide (1-2) (desulfated); L-Aspartyl-L-Tyrosine; (S)-3-amino-4-((S)-1-carboxy-2-(4-hydroxyphenyl)ethylamino)-4-oxobutanoic acid. Grade: 95%. CAS No. 22840-03-5. Molecular formula: C13H16N2O6. Mole weight: 296.28. BOC Sciences 10
H-Ile-lys-asn-leu-gln-ser-leu-asp-pro-ser-his-oh H-Ile-lys-asn-leu-gln-ser-leu-asp-pro-ser-his-oh. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CCK-33 (10-20) (BOVINE, PORCINE);CCK-39 (16-26) (BOVINE, PORCINE);CCK-58 (35-45) (BOVINE, PORCINE);CHOLECYSTOKININ-33 (10-20) (BOVINE, PORCINE);CHOLECYSTOKININ (10-20);ILE-LYS-ASN-LEU-GLN-SER-LEU-ASP-PRO-SER-HIS;IKNLQSLDPSH;H-ILE-LYS-ASN-LEU-GLN-SER-LEU-. Product Category: Heterocyclic Organic Compound. CAS No. 100900-23-0. Molecular formula: C54H90N16O18. Mole weight: 1251.39. Product ID: ACM100900230. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 4
[Leu15]-Gastrin I (human) [Leu15]-Gastrin I (human) is a Gastrin I, human (HY-P1097) peptide hormone derivative, which is trophic for normal gastrointestinal epithelium. Gastrin stimulates growth of gastric adenocarcinoma (gastric cancer) through G-protein-coupled receptor called the cholecystokinin (CCK) or cholecystokinin-B receptors (CCK-BR) that are overexpressed in this malignancy. [Leu15]-Gastrin I (human) is promising for research of gastric cancer[1][2][3][4]. Uses: Scientific research. Group: Peptides. CAS No. 39024-57-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2671. MedChemExpress MCE
Loxiglumide Loxiglumide is a cholecystokinin ( CCK-1 ) receptor antagonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CR-1505. CAS No. 107097-80-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B2154. MedChemExpress MCE
LY 225910 LY 225910 is a selective antagonist for cholecystokinin receptor ( CCK2 receptor ), which affects the excitatory response to morphine, and leads to morphine sensitization [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 133040-77-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101352. MedChemExpress MCE
Native Porcine Pancreozymin Cholecystokinin is a peptide hormone of the gastrointestinal system responsible for stimulating the digestion of fat and protein. Cholecystokinin, previously called pancreozymin, is synthesized by I-cells in the mucosal epithelium of the small intestine and secreted in the duodenum, the first segment of the small intestine, and causes the release of digestive enzymes and bile from the pancreas and gallbladder, respectively. It also acts as a hunger suppressant. Recent evidence has suggested that it also plays a major role in inducing drug tolerance to opioids like morphine and heroin, and is partly implicated in experiences of pain hypersensitivity during opioid withdrawal. Applications: Cholecystokinin (cck) is a peptide hormone of the gastrointestinal system responsible for stimulating the digestion of fat and protein. it is used to study brain, kidney and pancreatic functioning as well as reproductive behavior and glucose tolerance. Group: Enzymes. Synonyms: Cholecystokinin, CCK, CCK-PZ; 9011-97-6; Pancreozymin. CAS No. 9011-97-6. CCK. Activity: 2-6 Crick units/mg solid. Storage: 2-8°C. Source: Porcine intestine. Species: Porcine. Cholecystokinin, CCK, CCK-PZ; 9011-97-6; Pancreozymin. Cat No: NATE-0113. Creative Enzymes
Neuropeptide Y (porcine) Neuropeptide Y (porcine) is a widely distributed endogenous neuropeptide involved in regulation of circadian rhythms, sexual functioning, anxiety and stress response, and regulation of food intake (Ki= 0.17, 0.04 nM at human and Y2 respectively). It inhibits cholecystokinin- and secretin-stimulated pancreatic secretion. Synonyms: H-Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Leu-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr-NH2. CAS No. 83589-17-7. Molecular formula: C190H287N55O57. Mole weight: 4254. BOC Sciences
Pancreatic Polypeptide, bovine Pancreatic Polypeptide, bovine, a straight chain polypeptide containing 36 amino acids, derived primarily from the pancreas, and stimulates pancreatic secretion by inhibiting secretin and cholecystokinin. As the NPY receptor agonist, it has a high affinity at NPYR4. Synonyms: Ala-Pro-Leu-Glu-Pro-Glu-Tyr-Pro-Gly-Asp-Asn-Ala-Thr-Pro-Glu-Gln-Met-Ala-Gln-Tyr-Ala-Ala-Glu-Leu-Arg-Arg-Tyr-Ile-Asn-Met-Leu-Thr-Arg-Pro-Arg-Tyr-NH2; Pancreatic polypeptide (pig), 6-L-glutamic acid-; Bovine pancreatic polypeptide. Grade: ≥95%. CAS No. 179986-89-1. Molecular formula: C186H287N53O56S2. Mole weight: 4225.78. BOC Sciences
Pentagastrin Pentagastrin (ICI-50123) is a potent, selective Cholecystokinin B (CCK B ) receptor antagonists with IC 50 values of 11 nM and 1100 nM for CCK B and CCK A , respectively. Pentagastrin enhances gastric mucosal defense mechanisms against acid and protects the gastric mucosa from experimental injury [1]. [2]. Uses: Scientific research. Group: Peptides. Alternative Names: ICI-50123. CAS No. 5534-95-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0261. MedChemExpress MCE
Pranazepide Pranazepide (FR120480) is a cholecystokinin-A receptor antagonist [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FR120480. CAS No. 150408-73-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105257. MedChemExpress MCE
Proglumide Anticholinergic, cholecystokinin Receptor. Group: Biochemicals. Alternative Names: 4-(Benzoylamino)-5-(dipropylamino)-5-oxo-pentanoic Acid; DL-4-Benzamido-N,N-dipropylglutaramic Acid; (+/-)-Proglumide; Binoside; CR 242; DL-4-Benzamido-N,N-dipropylglutaramic Acid; DL-Proglumide; Gastrotopic; Midelid; Milid; Milide; Nulsa; Promid; Ulcutin; W 5219; Xyde; Xylamide; Xylamide. Grades: Highly Purified. CAS No. 6620-60-6. Pack Sizes: 1g. US Biological Life Sciences. USBiological 2
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Proglumide Proglumide is a nonpeptide and orally active cholecystokinin (CCK)-A/B receptors antagonist. Proglumide selective blocks CCK s effects in the central nervous system (CNS). Proglumide has ability to inhibit gastric secretion and to protect the gastroduodenal mucosa. Proglumide also has antiepileptic and antioxidant activities [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 6620-60-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B1330. MedChemExpress MCE
Proglumide sodium Proglumide sodium is a nonpeptide and orally active cholecystokinin (CCK)-A/B receptors antagonist. Proglumide sodium selective blocks CCK s effects in the central nervous system (CNS). Proglumide sodium has ability to inhibit gastric secretion and to protect the gastroduodenal mucosa. Proglumide sodium also has antiepileptic and antioxidant activities [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 99247-33-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-103354. MedChemExpress MCE
Sincalide It is a synthetically-prepared C-terminal octapeptide of cholecystokinin.Sincalide (INN) is a cholecystokinetic drug administered by injection to aid in diagnosing disorders of the gallbladder and pancreas. It is the 8-amino acid C-terminal fragment of cholecystokinin. Synonyms: Sincalide. Grade: >98%. CAS No. 25126-32-3. Molecular formula: C49H62N10O16S3. Mole weight: 1143.29. BOC Sciences 8
Sincalide Sincalide (Cholecystokinin octapeptide, CCK?8) is a rapid-acting amino acid polypeptide hormone analogue of cholecystokinin (CCK) for intravenous use in postevacuation cholecystography. CCK?8 is a major bioactive segment of CCK that retains most of the biological activities of CCK. CCK?8 can promote gallbladder contraction by injection and helps diagnose gallbladder and pancreas disorders. CCK?8 can increase bile secretion, cause the gallbladder to contract and relax the sphincter of Oddi, resulting in bile drainage into the duodenum. CCK?8 is a major bioactive segment of CCK that retains most of the biological activities of CCK [1] [2] [3]. Uses: Scientific research. Group: Peptides. Alternative Names: Cholecystokinin octapeptide; CCK-8; SQ19844. CAS No. 25126-32-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0093. MedChemExpress MCE
Sincalide ammonium Sincalide ammonium (Cholecystokinin octapeptide ammonium, CCK-8 ammonium) is a rapid-acting amino acid polypeptide hormone analogue of cholecystokinin (CCK) for intravenous use in postevacuation cholecystography. Sincalide ammonium is a major bioactive segment of CCK that retains most of the biological activities of CCK. CCK?8 can promote gallbladder contraction by injection and helps diagnose gallbladder and pancreas disorders. Sincalide ammonium can increase bile secretion, cause the gallbladder to contract and relax the sphincter of Oddi, resulting in bile drainage into the duodenum. Sincalide ammonium is a major bioactive segment of CCK that retains most of the biological activities of CCK [1] [2] [3]. Uses: Scientific research. Group: Peptides. Alternative Names: Cholecystokinin octapeptide ammonium; CCK-8 ammonium; SQ19844 ammonium. CAS No. 70706-98-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0093A. MedChemExpress MCE
Tetragastrin Tetragastrin, also known as Cholecystokinin tetrapeptide or CCK-4, is the C-terminal tetrapeptide of gastrin, consisting of the sequence L-tryptophan, L-methionine, L-aspartic acid, and L-phenylalaninamide (Trp-Met-Asp-Phe amide). It is the smallest peptide fragment of gastrin that retains the same physiological and pharmacological activity as gastrin. Tetragastrin stimulates gastric secretion and acts as a Cholecystokinin (CCK-4) receptor agonist. It is known for its gastric mucosal protective effects and is used to improve symptoms of hypochlorhydria or gastric atony, as well as in the treatment of atrophic gastritis. Tetragastrin is also recognized for its role in anxiety control and gastric acid secretion. Synonyms: Gastrin tetrapeptide; Cholecystokinin tetrapeptide; CCK-4; (S)-4-(((S)-1-Amino-1-oxo-3-phenylpropan-2-yl)amino)-3-((S)-2-((S)-2-amino-3-(1H-indol-3-yl)propanamido)-4-(methylthio)butanamido)-4-oxobutanoic acid; 4-7-Cholecystokinin-7 (swine); L-Tryptophyl-L-methionyl-L-α-aspartyl-L-phenylalaninamide; H-Trp-Met-Asp-Phe-NH2; H-WMDF-NH2; Cholecystokinin fragment 30-33 amide; Cholecystokinin C-terminal tetrapeptide; Cholecystokinin (36-39). Grade: ≥95%. CAS No. 1947-37-1. Molecular formula: C29H36N6O6S. Mole weight: 596.71. BOC Sciences

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