Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases transposing C=C bonds. This enzyme participates in biosynthesis of steroids. Group: Enzymes. Enzyme Commission Number: EC 5.3.3.5. CAS No. 52410-46-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5502; cholestenol Δ-isomerase; EC 5.3.3.5; 52410-46-5. Cat No: EXWM-5502.
20a-Hydroxycholesterol (5-Cholestene-3B,20a-diol)
An important intermediate in corticosteroid biogenesis. Group: Biochemicals. Alternative Names: 5-Cholestene-3B,20a-diol. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
3BETA-HYDROXY-5-CHOLESTENE 3-HEMISUCCINATE TRIS SALT
3BETA-HYDROXY-5-CHOLESTENE 3-HEMISUCCINATE TRIS SALT. CAS No. 102601-49-0. Molecular formula: C35H61NO7. Mole weight: 607.86. Catalog: ACM102601490.
3β-Hydroxy-5-cholestenoic acid
3β-Hydroxy-5-cholestenoic acid is an active metabolite of cholesterol formed when cholesterol is metabolized by the cytochrome P450 (CYP) isomer CYP27A1. Synonyms: Cholest-5-en-26-oic acid, 3-hydroxy-, (3β)-; (3β)-3-Hydroxycholest-5-en-26-oic acid; Cholest-5-en-26-oic acid, 3β-hydroxy-; 3β-Hydroxycholest-5-en-26-oic acid; 3β-Hydroxycholest-5-en-27-oic acid; (6R)-6-((3S,8S,9S,10R,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-methylheptanoic acid; Cholesterol-26-carboxylic Acid. Grades: ≥95%. CAS No. 6561-58-6. Molecular formula: C27H44O3. Mole weight: 416.64.
3 β-Hydroxy-5-cholestenoic Acid
A metabolite of Cholesterol. Group: Biochemicals. Alternative Names: 3 β-Hydroxycholest-5-en-26-oic Acid; Cholesterol-26-carboxylic Acid; β-Hydroxycholest-5-en-26-oic Acid. Grades: Highly Purified. CAS No. 6561-58-6. Pack Sizes: 1mg. US Biological Life Sciences.
25g Pack Size. Group: Biochemicals, Building Blocks, Chiral Compounds. Formula: C27H44O. CAS No. 601-57-0. Prepack ID 18488191-25g. Molecular Weight 384.65. See USA prepack pricing.
4-Cholesten-3-one
4-Cholesten-3-one. Group: Biochemicals. Grades: Highly Purified. CAS No. 601-57-0. Pack Sizes: 25g, 50g, 100g, 250g, 500g. Molecular Formula: C27H44O. US Biological Life Sciences.
Worldwide
4-Cholesten-3-one
5g Pack Size. Group: Biochemicals, Building Blocks, Chiral Compounds. Formula: C27H44O. CAS No. 601-57-0. Prepack ID 18488191-5g. Molecular Weight 384.65. See USA prepack pricing.
7α-Hydroxy-4-cholesten-3-one is a metabolite of Cholesterol. Group: Biochemicals. Alternative Names: (7α)-7-Hydroxycholest-4-en-3-one; 7α-Hydroxycholest-4-en-3-one. Grades: Highly Purified. CAS No. 3862-25-7. Pack Sizes: 1mg. Molecular Formula: C27H44O2, Molecular Weight: 400.64. US Biological Life Sciences.
Worldwide
7α-Hydroxy-4-cholesten-3-one
7α-Hydroxy-4-cholesten-3-one is an intermediate in synthesis of bile acids from cholesterol. 7α-Hydroxy-4-cholesten-3-one is a pregnane X receptor (PXR) agonist. 7α-Hydroxy-cholest-4-en-3-one is a biomarker for bile acid loss, irritable bowel syndrome, and other diseases associated with defective bile acid biosynthesis. 7α-Hydroxy-cholest-4-en-3-one is the physiological substrate for CYP8B1 [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 3862-25-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-113259.
7α-Hydroxy-4-cholesten-3-one-d7
7α-Hydroxy-4-cholesten-3-one-d 7 is the deuterium labeled 7α-Hydroxy-4-cholesten-3-one. 7α-Hydroxy-4-cholesten-3-one is an intermediate in synthesis of bile acids from cholesterol. 7α-Hydroxy-4-cholesten-3-one is a pregnane X receptor (PXR) agonist. 7α-Hydroxy-cholest-4-en-3-one is a biomarker for bile acid loss, irritable bowel syndrome, and other diseases associated with defective bile acid biosynthesis. 7α-Hydroxy-cholest-4-en-3-one is the physiological substrate for CYP8B1[1][2]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 2260669-17-6. Pack Sizes: 5 mg; 500 μg. Product ID: HY-113259S.
7α-Hydroxy-4-cholesten-3-one-d7
Labeled 7α-Hydroxy-4-cholesten-3-one. 7α-Hydroxy-4-cholesten-3-one is a metabolite of Cholesterol. Group: Biochemicals. Alternative Names: (7α)-. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences.
12-[[ (1, 1-Dimethylethyl) dimethylsilyl]oxy]-3, 15-dihydroxy-cholest-5-en-26-oic Acid is an intermediate in the synthesis of (25R)-3 β, 7α, 12α-Trihydroxy-5-cholestenoic Acid (T795130), which is an oxysterol, an oxidized derivatives of cholesterol (C432501), which may be important in many biological processes, including cholesterol homeostasis, atherosclerosis, sphingolipid metabolism, platelet aggregation, apoptosis, and protein prenylation,[1] though their roles are poorly understood. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 2.5mg. Molecular Formula: C33H58O5Si. US Biological Life Sciences.
Worldwide
12-Hydroxy-3-oxo-cholest-4-en-26-oic Acid
12-Hydroxy-3-oxo-cholest-4-en-26-oic Acid is an intermediate in the synthesis of (25R)-3 β, 7α, 12α-Trihydroxy-5-cholestenoic Acid (T795130), which is an oxysterol, an oxidized derivatives of cholesterol (C432501), which may be important in many biological processes, including cholesterol homeostasis, atherosclerosis, sphingolipid metabolism, platelet aggregation, apoptosis, and protein prenylation,[1] though their roles are poorly understood. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 2.5mg. Molecular Formula: C27H40O4. US Biological Life Sciences.
22(S)-Hydroxy cholesterol is a synthetic oxysterol and a modulator of the liver X receptor (LXR). Synonyms: cholest-5-ene-3β,22(S)-diol; 22(S)-Hydroxycholesterol; 5-cholestene-3β,22-diol; 22-hydroxycholest-5-en-3-ol; 22β-Hydroxy Cholesterol; (3β,22S)-Cholest-5-ene-3,22-diol; (20S,22S)-Cholest-5-ene-3β,22-diol; (22S)-22-Hydroxycholesterol; (22S)-Cholest-5-ene-3β,22-diol; (22β)-Hydroxycholesterol; Narthesterol. Grades: ≥95%. CAS No. 22348-64-7. Molecular formula: C27H46O2. Mole weight: 402.65.
25-Hydroxy Cholesterol
An oxygenated derivative of Cholesterol; an oxysterol. An inhibitor of human immunodeficiency virus replication in vitro. It induces apoptosis in human monocytic cell lines as well as inducing apoptosis in CEM cells associated with negative regulation of c-Myc. Group: Biochemicals. Alternative Names: (3 β)-Cholest-5-ene-3,25-diol; Cholest-5-ene-3 β,25-diol; 25-Hydroxy-5-cholestene-3 β-ol; 5-Cholesten-3 β,25-diol. Grades: Highly Purified. CAS No. 2140-46-7. Pack Sizes: 10mg, 25mg, 100mg. US Biological Life Sciences.
Worldwide
25-Hydroxy-Cholesterol
25-hydroxycholesterol is an inhibitor of human immunodeficiency virus replication in vitro. It induces apoptosis in human monocytic cell lines as well as in CEM cells associated with negative regulation of c-Myc. Synonyms: (3β)-Cholest-5-ene-3,25-diol; Cholest-5-ene-3β,25-diol; 25-Hydroxy-5-cholestene-3β-ol; 5-Cholesten-3β,25-diol. Grades: >98%. CAS No. 2140-46-7. Molecular formula: C27H46O2. Mole weight: 402.65.
25R-3α, 7α, 12α-Trihydroxy-5 β-cholestanoic Acid
25R-3α, 7α, 12α-Trihydroxy-5 β-cholestanoic acid is an intermediate in the synthesis of (25R)-3 β, 7α, 12α-Trihydroxy-5-cholestenoic Acid (T795130), which is an oxysterol, an oxidized derivatives of cholesterol (C432501), which may be important in many biological processes, including cholesterol homeostasis, atherosclerosis, sphingolipid metabolism, platelet aggregation, apoptosis, and protein prenylation,[1] though their roles are poorly understood. Group: Biochemicals. Grades: Highly Purified. CAS No. 23740-14-9. Pack Sizes: 10mg, 25mg. Molecular Formula: C27H46O5. US Biological Life Sciences.
Worldwide
27-Hydroxycholesterol
27-Hydroxycholesterol, a desmosterol metabolite found in the brain , activates LXRα (EC50= 85 nM)and LXRβ (EC50= 71 nM) in vitro. 27-HC is also an estrogen receptor partial agonist. It suppresses β-estradiol-mediated breast cancer cell proliferation in vitro. Synonyms: cholest-(25R)-5-ene-3β,27-diol; (25R)-Cholest-5-ene-3β,26-diol; 27-OHC; 5,25R-Cholesten-3beta,26-diol; (25R)-26-Hydroxycholesterol. Grades: >99%. CAS No. 20380-11-4. Molecular formula: C27H46O2. Mole weight: 402.65.
3b,7a-Hydroxy-(25R)-cholest-5-en-26-oic acid
3b,7a-Hydroxy-(25R)-cholest-5-en-26-oic acid. Group: Biochemicals. Alternative Names: 3b,7a-Dihydroxy-5-cholestenoic acid. Grades: Highly Purified. CAS No. 115538-84-6. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C27H44O4. US Biological Life Sciences.
(3 β)-3-O-tert-Butyldimethylsilyl-cholest-5-ene-3,24-diol is a reactant used in the preparation of series of cholesterol side-chain analogs used in studies of the ω-regiospecificity of Mycobacterium tuberculosis cholesterol metabolizing cytochrome P 450 enzymes. It is used in the preparation of (25S)-Δ7-dafachronic acid, (25S)-Δ4-dafachronic acid, (25S)-dafachronic acid, and (25S)-cholestenoic acid. Group: Biochemicals. Alternative Names: (3 β ) -3-[[ (1, 1-Dimethylethyl) dimethylsilyl]oxy]-chol-5-en-24-ol. Grades: Highly Purified. CAS No. 84529-86-2. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
3-Keto Cholesterol
A metabolite of Cholesterol. Group: Biochemicals. Alternative Names: Cholest-5-en-3-one; ?5-Cholesten-3-one;3-Oxocholest-5-ene; 5-Cholestenone; NSC 118979. Grades: Highly Purified. CAS No. 601-54-7. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
3-oxo-5α-steroid 4-dehydrogenase (NADP+)
The enzyme catalyses the conversion of assorted 3-oxo-Δ4 steroids into their corresponding 5α form. Substrates for the mammalian enzyme include testosterone, progesterone, and corticosterone. Substrates for the plant enzyme are brassinosteroids such as campest-4-en-3-one and (22α)-hydroxy-campest-4-en-3-one. cf. EC 1.3.99.5, 3-oxo-5α-steroid 4-dehydrogenase (acceptor). Group: Enzymes. Synonyms: cholestenone 5α-reductase; testosterone Δ4-5&. Enzyme Commission Number: EC 1.3.1.22. CAS No. 37255-34-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1297; 3-oxo-5α-steroid 4-dehydrogenase (NADP+); EC 1.3.1.22; 37255-34-8; cholestenone 5α-reductase; testosterone Δ4-5α-reductase; steroid 5α-reductase; 3-oxosteroid Δ4-dehydrogenase; 5α-reductase; steroid 5α-hydrogenase; 3-oxosteroid 5α-reductase; testosterone Δ4-hydrogenase; 4-ene-3-oxosteroid 5α-reductase; reduced nicotinamide adenine dinucleotide phosphate:Δ4-3-ketosteroid 5α-oxidoreductase; 4-ene-5α-reductase; Δ4-3-ketosteroid 5α-oxidoreductase; cholest-4-en-3-one 5α-reductase; testosterone 5α-reductase; 3-oxo-5α-steroid 4-dehydrogenase. Cat No: EXWM-1297.
4α-Methylzymosterol
4α-Methylzymosterol. Group: Biochemicals. Alternative Names: 4α-Methyl-Δ8,24-cholestenol; 4α-Methyl-5α-cholesta-8(9),24-dien-3 β-ol; (3 β, 4α, 5α)-4-Methyl-cholesta-8, 24-dien-3-ol; 4α-Methyl-Δ8,24-cholestenol. Grades: Highly Purified. CAS No. 7448-3-5. Pack Sizes: 1mg. Molecular Formula: C28H46O, Molecular Weight: 398.66. US Biological Life Sciences.
Worldwide
4-beta-Hydroxy Cholesterol
4-beta-Hydroxy Cholesterol is a metabolite of Cholesterol. It is formed from Cholesterol by the drug-metabolizing enzyme cytochrome P 450 3A4. It is also a potential ligand for the nuclear receptor LXR and also a new endogenous CYP3A marker. Synonyms: (3β,4β)-Cholest-5-ene-3,4-diol; Cholest-5-ene-3β,4β-diol; 3β,4β-Dihydroxycholest-5-ene; cis-3,4-Dihydroxy-5-cholestene; cis-5-Cholestene-3,4-diol. Grades: > 95%. CAS No. 17320-10-4. Molecular formula: C27H46O2. Mole weight: 402.65.
7α,25-Dihydroxycholesterol
7α,25-Dihydroxycholesterol has been found to be an agonist of GPR183 and could desensitize B cells expressing GPR183 and reduce their movement to splenic follicles. Synonyms: 7alpha,25-OHC; (3β,7α)-Cholest-5-ene-3,7,25-triol; Cholest-5-ene-3beta,7alpha,25-triol; 5-Cholesten-3beta,7alpha,25-triol. Grades: ≥98% by HPLC. CAS No. 64907-22-8. Molecular formula: C27H46O3. Mole weight: 418.65.
7α-hydroxycholest-4-en-3-one 12α-hydroxylase
A P-450 heme-thiolate protein. Requires EC 1.6.2.4, NADPH-hemoprotein reductase and cytochrome b5 for maximal activity. This enzyme is important in bile acid biosynthesis, being responsible for the balance between the formation of cholic acid and chenodeoxycholic acid. Group: Enzymes. Synonyms: 7α-hydroxy-4-cholesten-3-one 12α-monooxygenase; CYP12; sterol 12α-hydroxylase (ambiguous); HCO 12α-hydroxylase. Enzyme Commission Number: EC 1.14.18.8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0970; 7α-hydroxycholest-4-en-3-one 12α-hydroxylase; EC 1.14.18.8; 7α-hydroxy-4-cholesten-3-one 12α-monooxygenase; CYP12; sterol 12α-hydroxylase (ambiguous); HCO 12α-hydroxylase. Cat No: EXWM-0970.
7β-Hydroxy Cholesterol
7β-Hydroxy Cholesterol is a metabolite of Cholesterol. Increased levels of 7β-Hydroxycholesterol correlate with increased risk of cardiovascular diseases including atherosclerosis. Synonyms: (3β,7β)-Cholest-5-ene-3,7-diol; Cholest-5-ene-3β,7β-diol; 5-Cholestene-3β,7β-diol; 7β-Hydroxycholest-5-en-3β-ol. Grades: > 95%. CAS No. 566-27-8. Molecular formula: C27H46O2. Mole weight: 402.65.
Campesterol
Campesterol is a phytosterol, primarily found in nuts, fruits, legumes and seeds. It is poorly absorbed in humans and competitively inhibits the absorption of cholesterol. lt decreases the transcription of genes involved in cholesterol metabolism in hepatocytes and enterocytes and has positive impact in treatment of cardiovascular disease. lt was used as standard in GC1 and HPLC2 analysis of oil samples from plants. Synonyms: Campest-5-en-3beta-ol; Ergost-5-en-3beta-ol, (24R)-; Ergost-5-en-3-ol, (3beta,24R)-; 24α-Methyl-5-cholesten-3β-ol. Grades: >98%. CAS No. 474-62-4. Molecular formula: C28H48O. Mole weight: 400.68.
Campesterol-d7 (Mixture of Diastereomers)
Labeled Campesterol. A phytosterol, which may inhibit the intestinal absorption of cholesterol. Group: Biochemicals. Alternative Names: 5-Cholesten-24(RS)-methyl-d3-3 β-ol-d7. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
CHEMS
CHEMS is an acidic cholesterol ester. It self-assembles into bilayers in alkaline and neutral aqueous media. Synonyms: cholesteryl hemisuccinate; Cholesterol Hydrogen Succinate; 3beta-Hydroxy-5-cholestene 3-hemisuccinate. Grades: >99%. CAS No. 1510-21-0. Molecular formula: C31H50O4. Mole weight: 486.73.
Cholest-5-en-3-ol,acetate,(3a)-(9ci)
Heterocyclic Organic Compound. Alternative Names: 5-CHOLESTEN-3ALPHA-OL 3-ACETATE;5-CHOLESTEN-3-ALPHA-OL ACETATE;EPICHOLESTEROL ACETATE. CAS No. 1059-85-4. Molecular formula: C29H48O2. Mole weight: 428.69. Catalog: ACM1059854.
Cholesterol is a major component of all biological membranes; Cholesterol was found in all body tissues, especial in the brain, spinal cord, and in animal fats or oils. Group: Liquid crystal (lc) materials. Alternative Names: 3β-Acetoxy-5-cholestene. CAS No. 604-35-3. Pack Sizes: 25 kg/DRUMS. Product ID: [(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate. Molecular formula: 428.69. Mole weight: C29H48O2. XUGISPSHIFXEHZ-VEVYEIKRSA-N. 95%.
Cholesteryl Acetate
Cholesterol is a major component of all biological membranes; Cholesterol was found in all body tissues, especial in the brain, spinal cord, and in animal fats or oils. Group: Organic & printed electronicscholesteryl esters. Alternative Names: 3β-Acetoxy-5-cholestene. CAS No. 604-35-3. Molecular formula: C29H48O2. Mole weight: 428.69. Appearance: White fine crystalline powder or needles. Purity: 0.95. IUPACName: [(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate. Density: 0.99 g/cm³. Catalog: ACM604353.
The enzyme from human efficiently catalyses the reduction of progesterone, androstenedione, 17α-hydroxyprogesterone and testosterone to 5β-reduced metabolites; it can also act on aldosterone, corticosterone and cortisol, but to a lesser extent. The bile acid intermediates 7α,12α-dihydroxy-4-cholesten-3-one and 7α-hydroxy-4-cholesten-3-one can also act as substrates. Group: Enzymes. Synonyms: 3-oxo-Δ4-steroid 5β-reductase; 5β-reductase; androstenedione 5β-reductase; cholestenone 5β-reductase; cortis. Enzyme Commission Number: EC 1.3.1.3. CAS No. 9029-8-7. 3-oxo-5-beta-steroid 4-dehydrogenase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1303; Δ4-3-oxosteroid 5β-reductase; EC 1.3.1.3; 9029-08-7; 3-oxo-Δ4-steroid 5β-reductase; 5β-reductase; androstenedione 5β-reductase; cholestenone 5β-reductase; cortisone 5β-reductase; cortisone β-reductase; cortisone Δ4-5β-reductase; steroid 5β-reductase; testosterone 5β-reductase; Δ4-3-ketosteroid 5β-reductase; Δ4-5β-reductase; Δ4-hydrogenase; 4,5β-dihydrocortisone:NADP+ Δ4-oxidoreductase; 3-oxo-5β-steroid:NADP+ Δ4-oxidoreductase. Cat No: EXWM-1303.
Δ4-Dafachronic acid
DAF-12 is an orphan nuclear hormone receptor that regulates dauer larva diapause, reproductive development, fat metabolism, and life cycle/longevity in C. elegans. Δ4-Dafachronic acid is a racemic version of a sterol-derived hormone that acts as a ligand of DAF-12. Synonyms: 3-keto-4-Cholestenoic acid. Grades: ≥95%. CAS No. 23017-97-2. Molecular formula: C27H42O3. Mole weight: 414.6.
Izonsteride
Izonsteride, a benzothiazolyl derivative, has been found to be a cholestenone 5-alpha reductase inhibitor that was once studied in prostate cancer and probably be useful against androgenic alopecia and benign prostatic hyperplasia. Synonyms: Izonsteride; LY-320236; LY 320236; LY320236; UNII-A5E8C36F34.; (4AR,10BR)-8-[(4-ETHYL-1,3-BENZOTHIAZOL-2-YL)SULFANYL]-4,10B-DIMETHYL-1H,2H,3H,4H,4AH,5H,6H,10BH-BENZO[F]QUINOLIN-3-ONE. Grades: 98%. CAS No. 176975-26-1. Molecular formula: C24H26N2OS2. Mole weight: 422.62.
Lathosterol
A Cholesterol metabolite. Lathosterol (indicating cholesterol synthesis) and Sitosterol (indicating cholesterol absorption) also decreased with deteriorating health. Low Lathosterol, Sitosterol and Cholesterol predicted mortality additively and independently of each other. Group: Biochemicals. Alternative Names: (3 β,5α)-Cholest-7-en-3-ol; 5α-Cholest-7-en-3 β-ol; 3 β-Hydroxy-5α-cholest-7-ene; 7-En-3-cholestanol; Cholest-7-en-3-ol; Lathosterol; Δ7-Cholestenol; γ-Cholestenol. Grades: Highly Purified. CAS No. 80-99-9. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C??H??O, Molecular Weight: 386.65. US Biological Life Sciences.
Worldwide
Lathosterol
Lathosterol is an intermediate in the biosynthesis of cholesterol. Lathosterol in serum is carried on lipoproteins and is indicative of the rate of cholesterol synthesis. It acts as a marker of synthesis of cholesterol and is not affected by dietary consumption of cholesterol. Synonyms: 5alpha-Cholest-7-en-3beta-ol; Cholest-7-en-3-ol; 7-Cholesten-3-beta-ol. Grades: >99%. CAS No. 80-99-9. Molecular formula: C27H46O. Mole weight: 386.65.
MK 0434
MK 0434 is a Cholestenone 5-alpha reductase inhibitor originated by Merck & Co and it is associated with a significant reduction in dihydrotestosterone. No development was reported for the treatment of Alopecia, Benign prostatic hyperplasia and Prostate cancer. Uses: Alopecia, benign prostatic hyperplasia and prostate cancer. Synonyms: MK0434; MK-0434; MK 0434; MK-434; MK434; MK 434; (4aR,4bS,6aS,7S,9aS,9bS,11aR)-7-benzoyl-4a,6a-dimethyl-1,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-2H-indeno[5,4-f]quinolin-2-one;(5alpha,17beta)-17-Benzoyl-4-azaandrost-1-en-3-one;17beta-Benzoyl-4-aza-5alpha-androst-1-ene-3-one. Grades: 98%. CAS No. 134067-56-4. Molecular formula: C25H31NO2. Mole weight: 377.53.
Zymostenol
Zymostenol is a late-stage precursor in the biosynthesis of cholesterol.1 It is an agonist of retinoic acid receptor-related orphan receptor γ (RORγ) with an EC50 value of 1uM in a RORγ coactivator recruitment assay in the presence of ursolic acid. It increases the number of myelin basic protein-positive oligodendrocytes generated from oligodendrocyte precursor cells in vitro.2 Zymostenol accumulates in cells following administration of microsomal antiestrogen-binding site (AEBS) ligands, such as tamoxifen, which are associated with cell differentiation and a protective type of autophagy.3,4 When used alone at a concentration of 20uM, zymostenol halts the cell cycle at the G0/G1 phase and increases the levels of free sterols, esterified sterols, and triacylglycerols in MCF-7 cells.3. Group: Biochemicals. Alternative Names: 5α-Cholest-8-en-3 β-ol; 3 β-Hydroxy-5α-cholest-8(9)-ene; Dihydrozymosterol; Δ8-Cholestenol; (3 β,5α)-Cholest-8-en-3-ol. Grades: Highly Purified. CAS No. 566-97-2. Pack Sizes: 5mg, 10mg, 25mg. Molecular Formula: C27H46O, Molecular Weight: 386.65. US Biological Life Sciences.
Worldwide
Would you like to list your products on USA Chemical Suppliers?
Our database is helping our users find suppliers everyday.