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Cholesterol acetate Cholesterol acetate. Group: Liquid crystal (lc) building blocks. Alternative Names: Cholest-5-en-3-beta-yl acetate. CAS No. 604-35-3. Product ID: [(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate. Molecular formula: 428.69. Mole weight: C29H48O2. C[C@H] (CCCC (C)C)[C@H]1CC[C@@H]2[C@@]1 (CC[C@H]3[C@H]2CC=C4[C@@]3 (CC[C@@H] (C4)OC (=O)C)C)C. XUGISPSHIFXEHZ-VEVYEIKRSA-N. InChI=1S/C29H48O2/c1-19 (2)8-7-9-20 (3)25-12-13-26-24-11-10-22-18-23 (31-21 (4)30)14-16-28 (22, 5)27 (24)15-17-29 (25, 26)6/h10, 19-20, 23-27H, 7-9, 11-18H2, 1-6H3/t20-, 23+, 24+, 25-, 26+, 27+, 28+, 29-/m1/s1. Alfa Chemistry Materials 5
20-Dehydro cholesterol 3-acetate 20-Dehydro cholesterol 3-acetate. Group: Biochemicals. Alternative Names: (3b,20E)-Cholesta-5,20(22)-dien-3-ol 3-acetate; Cholesta-5,20(22)-dien-3b-ol acetate. Grades: Highly Purified. CAS No. 54548-85-5. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C29H46O2. US Biological Life Sciences. USBiological 7
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20-Dehydro cholesterol 3-acetate 20-Dehydro cholesterol 3-acetate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (3β,20E)-Cholesta-5,20(22)-dien-3-ol 3-Acetate; Cholesta-5,20(22)-dien-3β-ol Acetate. Product Category: Heterocyclic Organic Compound. CAS No. 54548-85-5. Molecular formula: C29H46O2. Mole weight: 426.67. Purity: 0.96. IUPACName: [(3R,8S,9S,10R,13S,14S,17R)-10,13-dimethyl-17-[(Z)-6-methylhept-2-en-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate. Product ID: ACM54548855. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 5
22-Dehydro 25-Hydroxy Cholesterol 3-Acetate Cholesterol derivative. Group: Biochemicals. Alternative Names: (3 β,22E)-Cholesta-5,22-diene-3,25-diol 3-Acetate. Grades: Highly Purified. CAS No. 157171-88-5. Pack Sizes: 5mg. US Biological Life Sciences. USBiological 2
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22-Dehydro Cholesterol-d7 3-Acetate Cholesterol derivative. Group: Biochemicals. Alternative Names: 5,22E-Cholestadien-3 β-ol-d7 Acetate; 5,22E-Cholestadien-3 β-yl-d7 Acetate; (3 β,22E)-Cholesta-5,22-dien-3-ol-d7 3-Acetate. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 2
Worldwide
4 β-Hydroxy Cholesterol 4-Acetate Cholesterol metabolite. Hydroximinosteroid analog with cytotoxic properties. Group: Biochemicals. Alternative Names: (3 β,4 β)-Cholest-5-ene-3,4-diol 4-Acetate; 4 β-Acetoxycholest-5-en-3 β-ol. Grades: Highly Purified. CAS No. 2515-18-6. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 2
Worldwide
4 β-Hydroxy Cholesterol-d7 4-Acetate Labeled Cholesterol metabolite. Hydroximinosteroid analog with cytotoxic properties. Group: Biochemicals. Alternative Names: (3 β,4 β)-Cholest-5-ene-3,4-diol-d7 4-Acetate; 4 β-Acetoxycholest-5-en-3 β-ol-d7. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 2
Worldwide
4b-Hydroxy cholesterol 4-acetate 4b-Hydroxy cholesterol 4-acetate. Group: Biochemicals. Alternative Names: (3b,4b)-Cholest-5-ene-3,4-diol 4-acetate; 4b-Acetoxycholest-5-en-3b-ol. Grades: Highly Purified. CAS No. 2515-18-6. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C29H48O3. US Biological Life Sciences. USBiological 7
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7 β-Hydroxy Cholesterol 3 β-Acetate Intermediate in the preparation of Cholesterol metabolites. Group: Biochemicals. Alternative Names: 7 β-Hydroxycholesteryl 3 β-Acetate. Grades: Highly Purified. CAS No. 17974-77-5. Pack Sizes: 5mg. US Biological Life Sciences. USBiological 2
Worldwide
7b-Hydroxy cholesterol 3b-acetate 7b-Hydroxy cholesterol 3b-acetate. Group: Biochemicals. Alternative Names: 7b-Hydroxycholesteryl 3b-acetate. Grades: Highly Purified. CAS No. 17974-77-5. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C29H48O3. US Biological Life Sciences. USBiological 7
Worldwide
7-Oxo Cholesterol 3-Acetate Intermediate in the preparation of various Cholesterol derivatives and metabolites. Group: Biochemicals. Alternative Names: (3 β)-3-(Acetyloxy)cholest-5-en-7-one; 3 β-Hydroxy-cholest-5-en-7-one Acetate; 7-Ketocholesteryl Acetate; 7-Oxocholest-5-en-3 β-yl Acetate; 7-Oxocholesteryl Acetate; NSC 59469. Grades: Highly Purified. CAS No. 809-51-8. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 2
Worldwide
7-Oxo Cholesterol-d7 3-Acetate Intermediate in the preparation of various Cholesterol derivatives and metabolites. Group: Biochemicals. Alternative Names: (3 β)-3-(Acetyloxy)cholest-5-en-7-one-d7; 3 β-Hydroxy-cholest-5-en-7-one-d7 Acetate; 7-Ketocholesteryl-d7 Acetate; 7-Oxocholest-5-en-3 β-yl-d7 Acetate; 7-Oxocholesteryl-d7 Acetate; NSC 59469-d7. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. USBiological 2
Worldwide
7-p-Toluene sulfonylhydrazide Cholesterol 3-Acetate Cholesterol derivative. Used in the preparation of 5,7-diene steroids. Group: Biochemicals. Alternative Names: 4-Methyl-benzenesulfonic Acid 2-[(3 β)-3-(Acetyloxy)cholest-5-en-7-ylidene]hydrazide; p-Toluenesulfonic Acid (3 β-Hydroxycholest-5-en-7-ylidene)hydrazide Acetate. Grades: Highly Purified. CAS No. 54201-67-1. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 3
Worldwide
7-p-Toluene sulfonylhydrazide Cholesterol-d7 3-Acetate Labeled Cholesterol derivative. Used in the preparation of 5,7-diene steroids. Group: Biochemicals. Alternative Names: 4-Methyl-benzenesulfonic Acid 2-[(3 β)-3-(Acetyloxy)cholest-5-en-7-ylidene]hydrazide-d7; p-Toluenesulfonic Acid (3 β-Hydroxycholest-5-en-7-ylidene)hydrazide-d7 Acetate. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 3
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Cholesterol 3-Acetate-d7 Isotope labelled Cholesterol 3-Acetate-d7 is an derivative of Cholesterol (C432501), a major component of all biological membranes. Group: Biochemicals. Alternative Names: (-)-Cholesteryl Acetate-d7; (3 β)-Cholest-5-en-3-ol Acetate-d7; 3-Cholesteryl Acetate-d7; 3 β-Acetoxycholest-5-ene-d7; Cholest-5-en-3 β-ol Acetate-d7; Cholest-5-en-3 β-yl Acetate-d7; Cholesterin Acetate-d7; Cholesterol 3-Acetate-d7; Cholesterol 3 β-Acetate-d7; Cholesteryl Acetate-d7; NSC 8799. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. USBiological 3
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19-Hydroxy Cholesteryl 3-Acetate A C-19 functionalized cholesterol derivative and popular substrate for steroid biotransformations. Group: Biochemicals. Alternative Names: (3 β)-Cholest-5-ene-3,19-diol 3-Acetate; 3 β-Acetoxycholest-5-en-19-ol; 19-Hydroxycholesterol 3-Acetate; 19-Hydroxycholesterol Acetate; NSC 123342. Grades: Highly Purified. CAS No. 750-59-4. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 2
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(22S)-22-Hydroxycholest-5-en-3 β-yl Acetate (22S)-22-Hydroxycholest-5-en-3 β-yl Acetate is an intermediate in the synthesis of 22S-metabolite of Cholesterol (C432501). Group: Biochemicals. Grades: Highly Purified. CAS No. 54604-57-8. Pack Sizes: 5mg, 50mg. Molecular Formula: C29H48O3. US Biological Life Sciences. USBiological 10
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3-O-Acetyl-26-hydroxy Cholesterol Intermediate in the production of cholesterol metabolites. Group: Biochemicals. Alternative Names: Cholest-5-ene-3 β,26-diol 3-acetate; (3 β)-Cholest-5-ene-3,26-diol 3-Acetate. Grades: Highly Purified. CAS No. 50681-37-3. Pack Sizes: 2mg. US Biological Life Sciences. USBiological 1
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3-O-Acetyl ezetimibe 2,3,4-tri-o-acetyl-β-D-glucuronide methyl ester An intermediate of Ezetimibe. Ezetimibe is a selective cholesterol absorption inhibitor that targets the Niemann-Pick C1-Like 1 (NPC1L1) protein in the small intestine, blocking dietary and biliary cholesterol uptake. Uses: Intermediate in the preparation of phase-ii metabolites of ezetimibe. glucuronide azetidinone cholesterol absorption inhibitor. Synonyms: β-D-Glucopyranosiduronic acid, 4-[(2S,3R)-3-[(3S)-3-(acetyloxy)-3-(4-fluorophenyl)propyl]-1-(4-fluorophenyl)-4-oxo-2-azetidinyl]phenyl, methyl ester, 2,3,4-triacetate; 4-[(2S,3R)-3-[(3S)-3-(Acetyloxy)-3-(4-fluorophenyl)propyl]-1-(4-fluorophenyl)-4-oxo-2-azetidinyl]phenyl β-D-Glucopyranosiduronic Acid Methyl Ester 2,3,4-Triacetate. Grade: ≥95%. CAS No. 190448-56-7. Molecular formula: C39H39F2NO13. Mole weight: 767.72. BOC Sciences 4
3-O-Acetyl Ezetimibe 2,3,4-Tri-O-acetyl- β-D-glucuronide Methyl Ester Intermediate in the preparation of Phase-II metabolites of Ezetimibe. Glucuronide azetidinone cholesterol absorption inhibitor. Group: Biochemicals. Alternative Names: 4-[(2S,3R)-3-[(3S)-3-(Acetyloxy)-3-(4-fluorophenyl)propyl]-1-(4-fluorophenyl)-4-oxo-2-azetidinyl]phenyl β-D-Glucopyranosiduronic Acid Methyl Ester 2,3,4-Triacetate. Grades: Highly Purified. CAS No. 190448-56-7. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 1
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3-O-Acetyl Ezetimibe-d4 2,3,4-Tri-O-acetyl- β-D-glucuronide Methyl Ester Labeled intermediate in the preparation of Phase-II metabolites of Ezetimibe. Glucuronide azetidinone cholesterol absorption inhibitor. Group: Biochemicals. Alternative Names: 4-[(2S,3R)-3-[(3S)-3-(Acetyloxy)-3-(4-fluorophenyl)propyl]-1-(4-fluorophenyl-d4)-4-oxo-2-azetidinyl]phenyl β-D-Glucopyranosiduronic Acid Methyl Ester 2,3,4-Triacetate. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 1
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Acetyl coenzyme A Acetyl coenzyme A is the precursor to HMG CoA, an essential component in the synthesis of cholesterol and ketone. Synonyms: Acetyl-CoA; S-Acetyl coenzyme A; AcCoA; Coenzyme A, S-acetate; S-acetyl-CoA. CAS No. 72-89-9. Molecular formula: C23H38N7O17P3S. Mole weight: 809.57. BOC Sciences 5
AS-186c AS-186c is an acyl-CoA: cholesterol acyltransferase (ACAT) inhibitor produced by Penicillum asperosporum KY1635. The IC50 for inhibiting ACAT was 11.5 μmol/L. Synonyms: 1-(7-{2-[2,6-dihydroxy-3-(3-methylbut-2-en-1-yl)benzoyl]-3-hydroxy-5-methylphenyl}-8,12-dihydroxy-4-methoxy-10-methyl-5-oxo-7,8-dihydro-5H-dibenzo[b,h][1,5]dioxonin-3-yl)-3-methylbutyl acetate. Molecular formula: C43H46O12. Mole weight: 754.82. BOC Sciences 12
AS-186d AS-186d is an acyl-CoA: cholesterol acyltransferase (ACAT) inhibitor produced by Penicillum asperosporum KY1635. The IC50 for inhibiting ACAT was 12.4 μmol/L. Synonyms: 1-(8,12-dihydroxy-7-{3-hydroxy-2-[6-hydroxy-3-(1-hydroxy-3-methylbutyl)-2-methoxybenzoyl]-5-methylphenyl}-4-methoxy-10-methyl-5-oxo-7,8-dihydro-5H-dibenzo[b,h][1,5]dioxonin-3-yl)-3-methylbutyl acetate. Molecular formula: C44H50O13. Mole weight: 786.86. BOC Sciences 12
Atorvastatin USP Related Compound I Atorvastatin USP Related Compound I is an impurity of Atorvastatin, which is an HMG-CoA reductase inhibitor used to reduce cholesterol and prevent cardiovascular-related disease. Synonyms: USP Atorvastatin Related Compound I; Atorvastatin acetonide impurity; tert-Butyl 2-((4R,6R)-6-{2-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]ethyl}-2,2-dimethyl-1,3-dioxan-4-yl)acetate; Atorvastatin Acetonide tert-Butyl Ester; (4R,6R)-6-[2-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester; Atorvastatin EP Impurity I; 1,3-Dioxane-4-acetic acid, 6-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-, 1,1-dimethylethyl ester, (4R,6R)-; 1,1-Dimethylethyl (4R,6R)-6-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetate; 1,3-Dioxane-4-acetic acid, 6-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-, 1,1-dimethylethyl ester, (4R-cis)-. Grade: ≥95%. CAS No. 125971-95-1. Molecular formula: C40H47FN2O5. Mole weight: 654.83. BOC Sciences 6
Cholesteryl acetate Cholesteryl acetate (Cholesterol 3-acetate) is a cholesterol ester [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Cholesterol 3-acetate; Cholesterin acetate; Cholesterol 3β-acetate. CAS No. 604-35-3. Pack Sizes: 50 mg; 100 mg. Product ID: HY-107823. MedChemExpress MCE
Cholesteryl acetate Cholesteryl acetate - Product ID: NST-10-92. Category: Sterols. Alternative Names: Acebrochol, Cholesterol, Cholesterin. Purity: 98%. Test method: HPLC. CAS No. 604-35-3. Pack Sizes: 5g, 10g, 25g, 50g. Appearance: White to beige colored powder. Molecular formula: C29H48O2. Mole weight: 428.7. Storage: +2 … +8 °C. NATURE SCIENCE TECHNOLOGIES
Cholesteryl Acetate Cholesterol is a major component of all biological membranes; Cholesterol was found in all body tissues, especial in the brain, spinal cord, and in animal fats or oils. Group: Liquid crystal (lc) materials. Alternative Names: 3β-Acetoxy-5-cholestene. CAS No. 604-35-3. Pack Sizes: 25 kg/DRUMS. Product ID: [(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate. Molecular formula: 428.69. Mole weight: C29H48O2. XUGISPSHIFXEHZ-VEVYEIKRSA-N. 95%. Alfa Chemistry Materials 6
FR901512 FR901512, a new specific inhibitor of HMG-CoA reductase, is isolated from the culture of an agonomycetous fungus No. 14919. FR901512 inhibits cholesterol synthesis from [14C] acetate in Hep G2 cells. Synonyms: 6-Heptenoic acid, 7-[(6R,8S)-8-(acetyloxy)-5,6,7,8-tetrahydro-2,6-dimethyl-1-naphthalenyl]-3,5-dihydroxy-, (3R,5S,6E)-; (3R,5S,E)-7-((6R,8S)-8-acetoxy-2,6-dimethyl-5,6,7,8-tetrahydronaphthalen-1-yl)-3,5-dihydroxyhept-6-enoic acid. CAS No. 151606-25-6. Molecular formula: C21H28O6. Mole weight: 376.44. BOC Sciences 12
Ganoderol A Ganoderol A,a natural triterpenoid found in the fruiting body of Ganoderma lucidum, has the activity of anti-inflammatory and protection against UVA damage, these founctions show that ganoderol A is a candidate for the development of a suitable product to protect skin from UV-induced photoaging. Ganoderol A exhibits potent inhibitory activity against angiotensin converting enzyme activity. Via conversion of acetate or mevalonate as a precursor of the compound, ganoderal A exhibits potent inhibitory activity against cholesterol biosynthesis. Uses: Anti-inflammatory. Synonyms: Ganodermenonol. Grade: >97%. CAS No. 104700-97-2. Molecular formula: C30H46O2. Mole weight: 438.7. BOC Sciences 9
Lapaquistat acetate Lapaquistat acetate (TAK-475) is a squalene synthase inhibitor, blocking the conversion of farnesyl diphosphate (FPP) to squalene in the cholesterol biosynthesis pathway[1]. Lapaquistat acetate is effective at lowering low-density lipoprotein cholesterol, but it might cause liver damage. Lapaquistat acetate is used for hypercholesterolemia and mevalonate kinase deficiency (MKD) research[2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAK-475. CAS No. 189060-13-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-16274. MedChemExpress MCE
Methyl 3-cyclopropyl-3-oxopropionate 3-Cyclopropyl-3-oxopropanoic Acid Methyl Ester is a reagent used in the synthesis of Pitavastatin, which is a potent HMG-CoA reductase inhibitor for hypercholesterolemia (elevated cholesterol) and prevention of cardiovascular disease. Uses: A reagent used in the synthesis of pitavastatin. Synonyms: Methyl 2-(Cyclopropylcarbonyl)acetate; β-Oxo-cyclopropanepropanoic Acid Methyl Ester; Cyclopropanepropanoic acid, β-oxo-, methyl ester; Methyl β-oxocyclopropanepropanoate. Grade: ≥95%. CAS No. 32249-35-7. Molecular formula: C7H10O3. Mole weight: 142.15. BOC Sciences 2
Native Clostridium tetani Tetanolysin Tetanolysin is a toxin produced by Clostridium tetani bacteria. Its function is unknown but it is believed to contribute to the pathogenesis of tetanus. The other C. tetani toxin, tetanospasmin, is more definitively linked to tetanus. Tetanolysin belongs to a family of protein toxins known as cytolysins which bind to cholesterol. Cytolysins form pores in the cytoplasmic membrane that allows for the passage of ions and other molecules into the cell. The molecular weight of tetanolysin is approximately 55 kDa daltons. Hemolytic activity of tetanolysin is determined using 2.5% rabbit red blood cells at 37°c for 40 min. Applications: Tetanolysin has been used to analyze the formation of lytic pores in red blood cells (rbcs). it has also been used to permeabilize infected rbcs. Group: Others. Synonyms: Tetanolysin. Mole weight: 55 kDa. Storage: 2-8°C. Form: lyophilized powder containing sodium chloride and sodium acetate. Source: Clostridium tetani. Tetanolysin. Cat No: NATE-0693. Creative Enzymes
Purpactin B Purpactin B is a cholesterol acyltransferase (ACAT) inhibitor produced by Pen. purpurogenum FO-6. Synonyms: 1-[2'-(hydroxymethyl)-4-methoxy-4'-methyl-3,6'-dioxo-3h-spiro[1-benzofuran-2,1'-cyclohexa[2,4]dien]-5-yl]-3-methylbutyl acetate. CAS No. 133806-60-7. Molecular formula: C23H26O7. Mole weight: 414.45. BOC Sciences 12
Pyripyropene A Pyripyropene A is a powerful acyl-CoA: cholesterol acyltransferase 2 (ACAT2) inhibitor produced by the fungus Aspergillus fumigatus FO 1289. It inhibits acyl-CoA: cholesterol acyltransferase with an IC50 of 58 nmol/L. Synonyms: (3S,4R,4aR,6S,6aS,12R,12aS,12bS)-4-(acetoxymethyl)-12-hydroxy-4,6a,12b-trimethyl-11-oxo-9-(pyridin-3-yl)-1,3,4,4a,5,6,6a,12,12a,12b-decahydro-2H,11H-benzo[f]pyrano[4,3-b]chromene-3,6-diyl diacetate; (3S,4R,4aR,6S,6aS,12R,12aS,12bS)-4-(Acetoxymethyl)-12-hydroxy-4,6a,12b-trimethyl-11-oxo-9-(pyridin-3-yl)-1,2,3,4,4a,5,6,6a,11,12,12a,12b-dodecahydrobenzo[f]pyrano[4,3-b]chromene-3,6-diyl diacetate. Grade: ≥95%. CAS No. 147444-03-9. Molecular formula: C31H37NO10. Mole weight: 583.62. BOC Sciences
1-[(3 β,7α)-3-(Acetyloxy)cholesta-5,8-dien-7-yl]-1,2-hydrazinedicarboxylic Acid 1,2-Diisoprpyl Ester 1-[(3 β,7α)-3-(Acetyloxy)cholesta-5,8-dien-7-yl]-1,2-hydrazinedicarboxylic Acid 1,2-Diisoprpyl Ester is an intermediate in the synthesis of Zymostenol, which is the derivative of Zymosterol (Z701520), an sterol intermediate in the biosynthesis of cholesterol (C432501). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg, 100mg. Molecular Formula: C37H60N2O6. US Biological Life Sciences. USBiological 9
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19-Carboxy cholesterol 19-Carboxy cholesterol. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (3β)-3-Hydroxycholest-5-en-19-oic Acid. Product Category: Heterocyclic Organic Compound. Appearance: White to Off-White Solid. CAS No. 26319-96-0. Molecular formula: C27H44O3. Mole weight: 416.64. Purity: 0.96. IUPACName: 2-[(3S,8S,9S,10S,13R,14S,17R)-3-hydroxy-13-methyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-10-yl]acetic acid. Canonical SMILES: CC(C)CCCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)CC(=O)O)C. Product ID: ACM26319960. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 4
2- (Acetyloxy) -1-[3, 5-dimethoxy-4- (benzoyloxy) phenyl]ethanone 2- (Acetyloxy) -1-[3, 5-dimethoxy-4- (benzoyloxy) phenyl]ethanone is an intermediate in the synthesis of Hirsutidin Chloride (H356800), which is an anthocyanidin found in the Madagascar Periwinkle (Catharanthus Roseus). Hirsutidin Chloride can be used in the preparation of plant based compounds to lower LDL cholesterol. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C19H18O7, Molecular Weight: 358.34. US Biological Life Sciences. USBiological 9
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2-Benzyloxy Atorvastatin Acetonide tert-Butyl Ester-[d5] 2-Benzyloxy Atorvastatin Acetonide tert-Butyl Ester-[d5] is the labelled analogue of 2-Benzyloxy Atorvastatin Acetonide tert-Butyl Ester, which is a metabolite of Atorvastatin. Uses: A deuterated intermediate of the metabolite of atorvastin, a selective, competitive hmg-coa reductase inhibitor. atorvastin is the only drug in its class specfically indicated for lowering both elevated ldl-cholesterol and triglycerides in patients with. Synonyms: 2-Benzyloxy Atorvastatin-d5 Acetonide tert-Butyl Ester. Grade: 98% atom D. CAS No. 265989-41-1. Molecular formula: C47H48D5FN2O6. Mole weight: 765.96. BOC Sciences
2-Hydroxy Atorvastatin Acetonide tert-Butyl Ester-[d5] 2-Hydroxy Atorvastatin Acetonide tert-Butyl Ester-[d5] is the labelled analogue of 2-Hydroxy Atorvastatin Acetonide tert-Butyl Ester, which is a metabolite of Atorvastatin. Uses: A deuterated intermediate of the metabolite of atorvastin, a selective, competitive hmg-coa reductase inhibitor. atorvastin is the only drug in its class specfically indicated for lowering both elevated ldl-cholesterol and triglycerides in patients with. Synonyms: 2-Hydroxy Atorvastatin-D5 Acetonide tert-Butyl Ester. Grade: 95% atom D. CAS No. 265989-42-2. Molecular formula: C40H42D5FN2O6. Mole weight: 675.84. BOC Sciences
2- (tert-Butoxycarbonyl oxyimino) phenyl acetonitri le 2- (tert-Butoxycarbonyl oxyimino) phenyl acetonitri le is used as a reagent in the synthesis of phosphono methyl ornithine. Also used in the preparation of cholesterol-tagged natural fusion-protein-derived peptides with potent antiviral activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 58632-95-4. Pack Sizes: 5g, 10g. Molecular Formula: C13H14N2O3. US Biological Life Sciences. USBiological 9
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3-O-Acetyl Ezetimibe An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L4) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4S)- 3-[(3S)-3-(acetyloxy)-3-(4-fluorophenyl)propyl]-1-(4-fluorophenyl)-4-(4-hydroxyphenyl)-2-Azetidinone. Grade: > 95%. CAS No. 190448-46-5. Molecular formula: C26H23F2NO4. Mole weight: 451.47. BOC Sciences 4
4-Benzyloxy Atorvastatin Acetonide tert-Butyl Ester-[d5] 4-Benzyloxy Atorvastatin Acetonide tert-Butyl Ester-[d5] is the labelled analogue of 4-Benzyloxy Atorvastatin Acetonide tert-Butyl Ester, which is a metabolite of Atorvastatin. Uses: A deuterated intermediate of the metabolite of atorvastin, a selective, competitive hmg-coa reductase inhibitor. atorvastin is the only drug in its class specfically indicated for lowering both elevated ldl-cholesterol and triglycerides in patients with. Synonyms: 4-Benzyloxy Atorvastatin-d5 Acetonide tert-Butyl Ester. Grade: 98% atom D. CAS No. 265989-37-5. Molecular formula: C47H48D5FN2O6. Mole weight: 765.96. BOC Sciences 2
5α-Bromo-6,19-epoxycholestanol 3-Acetate Intermediate in the chemical synthesis of cholesterol derivatives, and substrate for producing androsterone derivatives via bacterial steroid biotransformation. Group: Biochemicals. Alternative Names: (3 β,5α,6 β)-. Grades: Highly Purified. CAS No. 1258-07-7. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 2
Worldwide
5-Bromo-5α-cholestane-3,6-diol 3-Acetate Intermediate in the production of cholesterol derivatives. Group: Biochemicals. Alternative Names: 3 β-Acetoxy-5-bromo-5α-cholestan-6 β-ol. Grades: Highly Purified. CAS No. 1258-35-1. Pack Sizes: 25mg. US Biological Life Sciences. USBiological 2
Worldwide
Acetyl-Coenzyme A acetyltransferase 2 from Human, Recombinant ACAT2 enzyme participates in lipid metabolism. ACAT2 takes part in lipoprotein assembly, catalyzing cholesterol esterification in mammalian cells. ACAT2 is an integral membrane protein that localizes to the endoplasmic reticulum of human intestinal cells. ACAT2 deficiency contributes to severe mental retardation and hypotonus. Acat2 recombinant human produced in e. coli is a single, non-glycosylated polypeptide chain containing 433 amino acids (1-397 a.a.) and having a molecular mass of 45.4 kda. the acat2 is fused to 36 amino acid his-tag at n-terminus and purified by proprietary chromatographic techniques. Group: Enzymes. Synonyms: Acetyl-CoA acetyltransferase cytosolic; Cytosolic acetoacetyl-CoA thiolase; ACAT2; Acetyl CoA transferase-like protein; ACAT-2. Purity: Greater than 95.0% as determined by SDS-PAGE. ACAT-2. Mole weight: 45.4 kDa. Stability: ACAT2 Human although stable at 4°C for 1 week, should be stored desiccated below -18°C. Please prevent freeze thaw cycles. Appearance: Sterile Filtered clear solution. Source: E. coli. Species: Human. Acetyl-CoA acetyltransferase cytosolic; Cytosolic acetoacetyl-CoA thiolase; ACAT2; Acetyl CoA transferase-like protein; ACAT-2. Cat No: NATE-0798. Creative Enzymes
Acetyl coenzyme A sodium salt Acetyl coenzyme A sodium salt, a pivotal molecule in the biomedical industry, is widely utilized in fatty acid and cholesterol biosynthesis, as well as the citric acid cycle. Its role in drug and toxin metabolism and breakdown in the body is also noteworthy. Besides, it contributes to treating metabolic disorders such as diabetes, obesity, and cancer. Its multifaceted functions make it a molecule of great scientific significance. Synonyms: Acetyl CoA. Grade: 90%. CAS No. 102029-73-2. Molecular formula: C23H38N7O17P3S·xNa. Mole weight: 809.57 (free acid). BOC Sciences 5
Atorvastatin Acetonide Tert-Butyl Ester-[d5] Atorvastatin Acetonide Tert-Butyl Ester-[d5] is the labelled analogue of Atorvastatin Acetonide Tert-Butyl Ester, which is the intermediate of Atorvastatin. Uses: An deuterated intermediate of deuterated atorvastatin, a selective, competitive hmg-coa reductase inhibitor. the only drug in its class specfically indicated for lowering both elevated ldl-cholesterol and triglycerides in patients with hypercholesterolem. Synonyms: Atorvastatin Acetonide Tert-Butyl Ester-d5. Grade: 95% atom D. CAS No. 265989-34-2. Molecular formula: C40H42D5FN2O5. Mole weight: 659.84. BOC Sciences 2
Cancer Hydrolase KIAA1363 Inhibitor, JW480 (2’-Isopropylphenyl-2- (2-naphthyl) ethylcarbamate, AADACL1 Inhibitor, Arylacetamide Deacetylase-Like 1 Inhibitor, NCEH1 Inhibitor, Neutral Cholesterol Ester Hydrolase 1 Inhibitor) A membrane-permeable, highly potent and selective inhibitor against the 2-acetyl MAGE (monoakylglycerol ether) hydrolase KIAA1363/AADACL1 of both human (IC50=12nM; PC3 lysate) and murine (IC50=20nM; brain membrane samples) origin, with no significant effect toward other PC3 or murine brain serine hydrolase activities, including HSL, FAAH, and AChE. Readily crosses blood-brain barrier in mice and effectively suppresses PC3-derived tumor growth in mice in vivo (by 56% on day 33; 80mg/kg/day; o.g.). Also inhibits blood carboxylesterase. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 4
Worldwide
Cholesterol myristate Cholesterol myristate is a natural steroid present in traditional Chinese medicine. Cholesterol myristate binds to several ion channels such as the nicotinic acetylcholine receptor , GABAA receptor , and the inward-rectifier potassium ion channel. Uses: Scientific research. Group: Natural products. Alternative Names: Cholesteryl myristate; Cholesteryl tetradecanoate. CAS No. 1989-52-2. Pack Sizes: 500 mg; 1 g. Product ID: HY-N2338. MedChemExpress MCE
Ezetimibe Diacetate An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L5) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4S)-3-[(3S)-3-(Acetyloxy)-3-(4-fluorophenyl)propyl]-4-[4-(acetyloxy)phenyl]-1-(4-fluorophenyl)-2-azetidinone. Grade: > 95%. CAS No. 163380-20-9. Molecular formula: C28H25F2NO5. Mole weight: 493.51. BOC Sciences 8
fucosterol-epoxide lyase The insect enzyme is involved in the conversion of sitosterol into cholesterol. Group: Enzymes. Synonyms: (24R,24'R)-fucosterol-epoxide acetaldehyde-lyase; (24R,24'R)-fucosterol-epoxide acetaldehyde-lyase (desmosterol-forming). Enzyme Commission Number: EC 4.1.2.33. CAS No. 99676-42-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4870; fucosterol-epoxide lyase; EC 4.1.2.33; 99676-42-3; (24R,24'R)-fucosterol-epoxide acetaldehyde-lyase; (24R,24'R)-fucosterol-epoxide acetaldehyde-lyase (desmosterol-forming). Cat No: EXWM-4870. Creative Enzymes
GW 501516 An experimental drug meant to control lipids and increase the level of HDL, or good cholesterol, in the bloodstream. A cell-permeable, thiazolyl compound that acts as a potent, high affinity, PPARδ agonist. Exhibits selectivity for PPARδ compared to PPARα and PPARγ. Does not exibit any activity against other nuclear or non-nuclear receptors. Reported to increase cholesterol efflux and ABAC1 expression in macrophages, fibroblasts, and intestinal cells. Group: Biochemicals. Alternative Names: 2- [2-Methyl-4- [ [ [4-methyl-2- [4- (trifluoromethyl) phenyl] -5-thiazolyl] methyl] thio] phenoxy] acetic Acid; Methyl-methyl-trifluoromethylphenyl-thiazolyl-methylsulfanyl-phenoxy-acetic Acid; GW 1516; Endurobol. Grades: Highly Purified. CAS No. 317318-70-0. Pack Sizes: 10mg, 50mg. Molecular Formula: C??H??F?NO?S?, Molecular Weight: 453.5. US Biological Life Sciences. USBiological 7
Worldwide
Oleoyl coenzyme A lithium salt Coenzyme A functions as an acyl group carrier, acetyl-CoA. Oleoyl coenzyme A (Oleoyl-CoA) may be used to study the specificity and kinetics of enzymes such as acyl-coenzyme A:cholesterol acyltransferase 1 (ACAT1) involved in long chain fatty acid cholesterol esterification. Applications: May be used to study the specificity and kinetics of enzymes such as acyl-coenzyme a:cholesterol acyltransferase 1 (acat1). Group: Coenzymes. Synonyms: cis-9-Octadecenoyl coenzyme A. CAS No. 188824-37-5. Purity: ≥90%. Mole weight: 1031.98. Appearance: Powder. Form: Solid. cis-9-Octadecenoyl coenzyme A; Oleoyl coenzyme A lithium salt; 188824-37-5. Cat No: COEC-058. Creative Enzymes
Palmitoyl eicosapentaenoyl Phosphatidylcholine-d9 Palmitoyl eicosapentaenoyl Phosphatidylcholine-d9 is labelled Palmitoyl eicosapentaenoyl Phosphatidylcholine (P156900) which is a possible Cholesterol Acetyltransferase inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C44H69D9NO8P, Molecular Weight: 789.12. US Biological Life Sciences. USBiological 5
Worldwide
Pitavastatin Pitavastatin (NK-104) is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin inhibits cholesterol synthesis from acetic acid with an IC 50 of 5.8 nM in HepG2 cells. Pitavastatin is an efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer. Pitavastatin also possesses anti-atherosclerotic, anti-asthmatic, anti-osteoarthritis, antineoplastic, neuroprotective, hepatoprotective and reno-protective effects [1] [2] [3] [8]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NK-104. CAS No. 147511-69-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-B0144A. MedChemExpress MCE
Pitavastatin Calcium Pitavastatin Calcium (NK-104 hemicalcium) is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin Calcium (NK-104 hemicalcium) inhibits cholesterol synthesis from acetic acid with an IC 50 of 5.8 nM in HepG2 cells. Pitavastatin Calcium is an efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer. Pitavastatin Calcium also possesses anti-atherosclerotic, anti-asthmatic, anti-osteoarthritis, antineoplastic, neuroprotective, hepatoprotective and reno-protective effects [1] [2] [3] [8]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NK-104 hemicalcium; Pitavastatin hemicalcium. CAS No. 147526-32-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0144. MedChemExpress MCE
Purpactin A Purpactin A is a cholesterol acyltransferase (ACAT) inhibitor produced by Pen. purpurogenum FO-6. Synonyms: 1'-O-acetylpenicillide; Vermixocin B. Molecular formula: C23H26O7. Mole weight: 414.45. BOC Sciences
Pyripyropene A ((+)-Pyripyropene A, PPPA, FO 1289A) Antibiotic. Highly specific inhibitor of acyl-coenzyme A:cholesterol acetyltransferase 2 (ACAT2). Anti-angiogenic. Antiatherogenic and antiatherosclerotic agent. Shows cholesterol-lowering and atheroprotective activities. Group: Biochemicals. Alternative Names: (+)-Pyripyropene A, PPPA, FO 1289A. Grades: Highly Purified. CAS No. 147444-03-9. Pack Sizes: 250ug, 1mg. Molecular Formula: C31H37NO10, Molecular Weight: 583.6. US Biological Life Sciences. USBiological 3
Worldwide
Pyripyropene B Pyripyropene B is a powerful acyl-CoA: cholesterol acyltransferase 2 (ACAT2) inhibitor produced by the fungus Aspergillus fumigatus FO 1289. It inhibits acyl-CoA: cholesterol acyltransferase with an IC50 of 117 nmol/L. Synonyms: 2H,11H-Naphtho[2,1-b]pyrano[3,4-e]pyran-11-one,3,6-bis(acetyloxy)-1,3,4,4a,5,6,6a,12,12a,12b-decahydro-12-hydroxy-4,6a,12b-trimethyl-4-[(1-oxopropoxy)methyl]-9-(3-pyridinyl)-,(3S,4R,4aR,6S,6aS,12R,12aS,12bS)-. CAS No. 151519-44-7. Molecular formula: C32H39NO10. Mole weight: 597.65. BOC Sciences 12
Xylitol Xylitol can be classified as a polyol and sugar alcohol, exhibiting inhibitory activity on cancer cell proliferation. It induces autophagy ( Autophagy ) and cell death in A549 cells by activating the autophagy signaling pathway, as evidenced by the increased expression of LC3-II and Atg5-Atg12 upon Xylitol treatment. Additionally, Xylitol inhibits acetaldehyde production by Candida species, thereby reducing their carcinogenic potential. In vivo, Xylitol induces alterations in the gut microbiota of mice, which may enhance cholesterol accumulation and upregulate hepatic ChREBP, while also slowing tumor growth in the B16F10 melanoma C57BL/6 mouse model [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Xylite. CAS No. 87-99-0. Pack Sizes: 10 mM * 1 mL; 1 g. Product ID: HY-N0538. MedChemExpress MCE

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