Cholesterol Acetate Suppliers USA
Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
Product | Description | |
---|---|---|
Cholesterol Acetate Quick inquiry Where to buy Suppliers range | Cholesterol Acetate. Group: Liquid Crystal (LC) Building Blocks. CAS No. 604-35-3. IUPAC Name: [(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate. Molecular Weight: 428.7g/mol. Molecular Formula: C29H48O2. SMILES: CC (C)CCCC (C)C1CCC2C1 (CCC3C2CC=C4C3 (CCC (C4)OC (=O)C)C)C. InChI: InChI=1S/C29H48O2/c1-19(2)8-7-9-20(3)25-12-13-26-24-11-10-22-18-23(31-21(4)30)14-16-28(22,5)27(24)15-17-29(25,26)6/h10,19-20,23-27H,7-9,11-18H2,1-6H3/t20-,23+,24+,25-,26+,27+,28+,29-/m1/s1. InChIKey: XUGISPSHIFXEHZ-VEVYEIKRSA-N. | |
20-Dehydro cholesterol 3-acetate Quick inquiry Where to buy Suppliers range | 20-Dehydro cholesterol 3-acetate. Group: Biochemicals. Alternative Names: (3b,20E)-Cholesta-5,20(22)-dien-3-ol 3-acetate; Cholesta-5,20(22)-dien-3b-ol acetate. Grades: Highly Purified. CAS No. 54548-85-5. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C29H46O2. US Biological Life Sciences. | Worldwide |
22-Dehydro 25-Hydroxy Cholesterol 3-Acetate Quick inquiry Where to buy Suppliers range | Cholesterol derivative. Group: Biochemicals. Alternative Names: (3 β,22E)-Cholesta-5,22-diene-3,25-diol 3-Acetate. Grades: Highly Purified. CAS No. 157171-88-5. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
4 β-Hydroxy Cholesterol 4-Acetate Quick inquiry Where to buy Suppliers range | Cholesterol metabolite. Hydroximinosteroid analog with cytotoxic properties. Group: Biochemicals. Alternative Names: (3 β,4 β)-Cholest-5-ene-3,4-diol 4-Acetate; 4 β-Acetoxycholest-5-en-3 β-ol. Grades: Highly Purified. CAS No. 2515-18-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
4b-Hydroxy cholesterol 4-acetate Quick inquiry Where to buy Suppliers range | 4b-Hydroxy cholesterol 4-acetate. Group: Biochemicals. Alternative Names: (3b,4b)-Cholest-5-ene-3,4-diol 4-acetate; 4b-Acetoxycholest-5-en-3b-ol. Grades: Highly Purified. CAS No. 2515-18-6. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C29H48O3. US Biological Life Sciences. | Worldwide |
7 β-Hydroxy Cholesterol 3 β-Acetate Quick inquiry Where to buy Suppliers range | Intermediate in the preparation of Cholesterol metabolites. Group: Biochemicals. Alternative Names: 7 β-Hydroxycholesteryl 3 β-Acetate. Grades: Highly Purified. CAS No. 17974-77-5. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
7-Oxo Cholesterol 3-Acetate Quick inquiry Where to buy Suppliers range | Intermediate in the preparation of various Cholesterol derivatives and metabolites. Group: Biochemicals. Alternative Names: (3 β)-3-(Acetyloxy)cholest-5-en-7-one; 3 β-Hydroxy-cholest-5-en-7-one Acetate; 7-Ketocholesteryl Acetate; 7-Oxocholest-5-en-3 β-yl Acetate; 7-Oxocholesteryl Acetate; NSC 59469. Grades: Highly Purified. CAS No. 809-51-8. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
7-p-Toluene sulfonylhydrazide Cholesterol 3-Acetate Quick inquiry Where to buy Suppliers range | Cholesterol derivative. Used in the preparation of 5,7-diene steroids. Group: Biochemicals. Alternative Names: 4-Methyl-benzenesulfonic Acid 2-[(3 β)-3-(Acetyloxy)cholest-5-en-7-ylidene]hydrazide; p-Toluenesulfonic Acid (3 β-Hydroxycholest-5-en-7-ylidene)hydrazide Acetate. Grades: Highly Purified. CAS No. 54201-67-1. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
22-Dehydro Cholesterol-d7 3-Acetate Quick inquiry Where to buy Suppliers range | Cholesterol derivative. Group: Biochemicals. Alternative Names: 5,22E-Cholestadien-3 β-ol-d7 Acetate; 5,22E-Cholestadien-3 β-yl-d7 Acetate; (3 β,22E)-Cholesta-5,22-dien-3-ol-d7 3-Acetate. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
4 β-Hydroxy Cholesterol-d7 4-Acetate Quick inquiry Where to buy Suppliers range | Labeled Cholesterol metabolite. Hydroximinosteroid analog with cytotoxic properties. Group: Biochemicals. Alternative Names: (3 β,4 β)-Cholest-5-ene-3,4-diol-d7 4-Acetate; 4 β-Acetoxycholest-5-en-3 β-ol-d7. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
7b-Hydroxy cholesterol 3b-acetate Quick inquiry Where to buy Suppliers range | 7b-Hydroxy cholesterol 3b-acetate. Group: Biochemicals. Alternative Names: 7b-Hydroxycholesteryl 3b-acetate. Grades: Highly Purified. CAS No. 17974-77-5. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C29H48O3. US Biological Life Sciences. | Worldwide |
7-Oxo Cholesterol-d7 3-Acetate Quick inquiry Where to buy Suppliers range | Intermediate in the preparation of various Cholesterol derivatives and metabolites. Group: Biochemicals. Alternative Names: (3 β)-3-(Acetyloxy)cholest-5-en-7-one-d7; 3 β-Hydroxy-cholest-5-en-7-one-d7 Acetate; 7-Ketocholesteryl-d7 Acetate; 7-Oxocholest-5-en-3 β-yl-d7 Acetate; 7-Oxocholesteryl-d7 Acetate; NSC 59469-d7. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
7-p-Toluene sulfonylhydrazide Cholesterol-d7 3-Acetate Quick inquiry Where to buy Suppliers range | Labeled Cholesterol derivative. Used in the preparation of 5,7-diene steroids. Group: Biochemicals. Alternative Names: 4-Methyl-benzenesulfonic Acid 2-[(3 β)-3-(Acetyloxy)cholest-5-en-7-ylidene]hydrazide-d7; p-Toluenesulfonic Acid (3 β-Hydroxycholest-5-en-7-ylidene)hydrazide-d7 Acetate. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Cholesterol 3-Acetate-d7 Quick inquiry Where to buy Suppliers range | Isotope labelled Cholesterol 3-Acetate-d7 is an derivative of Cholesterol (C432501), a major component of all biological membranes. Group: Biochemicals. Alternative Names: (-)-Cholesteryl Acetate-d7; (3 β)-Cholest-5-en-3-ol Acetate-d7; 3-Cholesteryl Acetate-d7; 3 β-Acetoxycholest-5-ene-d7; Cholest-5-en-3 β-ol Acetate-d7; Cholest-5-en-3 β-yl Acetate-d7; Cholesterin Acetate-d7; Cholesterol 3-Acetate-d7; Cholesterol 3 β-Acetate-d7; Cholesteryl Acetate-d7; NSC 8799. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
1-[(3 β,7α)-3-(Acetyloxy)cholesta-5,8-dien-7-yl]-1,2-hydrazinedicarboxylic Acid 1,2-Diisoprpyl Ester Quick inquiry Where to buy Suppliers range | 1-[(3 β,7α)-3-(Acetyloxy)cholesta-5,8-dien-7-yl]-1,2-hydrazinedicarboxylic Acid 1,2-Diisoprpyl Ester is an intermediate in the synthesis of Zymostenol, which is the derivative of Zymosterol (Z701520), an sterol intermediate in the biosynthesis of cholesterol (C432501). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg, 100mg. Molecular Formula: C37H60N2O6. US Biological Life Sciences. | Worldwide |
19-Hydroxy Cholesteryl 3-Acetate Quick inquiry Where to buy Suppliers range | A C-19 functionalized cholesterol derivative and popular substrate for steroid biotransformations. Group: Biochemicals. Alternative Names: (3 β)-Cholest-5-ene-3,19-diol 3-Acetate; 3 β-Acetoxycholest-5-en-19-ol; 19-Hydroxycholesterol 3-Acetate; 19-Hydroxycholesterol Acetate; NSC 123342. Grades: Highly Purified. CAS No. 750-59-4. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
(22S)-22-Hydroxycholest-5-en-3 β-yl Acetate Quick inquiry Where to buy Suppliers range | (22S)-22-Hydroxycholest-5-en-3 β-yl Acetate is an intermediate in the synthesis of 22S-metabolite of Cholesterol (C432501). Group: Biochemicals. Grades: Highly Purified. CAS No. 54604-57-8. Pack Sizes: 5mg, 50mg. Molecular Formula: C29H48O3. US Biological Life Sciences. | Worldwide |
2- (Acetyloxy) -1-[3, 5-dimethoxy-4- (benzoyloxy) phenyl]ethanone Quick inquiry Where to buy Suppliers range | 2- (Acetyloxy) -1-[3, 5-dimethoxy-4- (benzoyloxy) phenyl]ethanone is an intermediate in the synthesis of Hirsutidin Chloride (H356800), which is an anthocyanidin found in the Madagascar Periwinkle (Catharanthus Roseus). Hirsutidin Chloride can be used in the preparation of plant based compounds to lower LDL cholesterol. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C19H18O7, Molecular Weight: 358.34. US Biological Life Sciences. | Worldwide |
2- (tert-Butoxycarbonyl oxyimino) phenyl acetonitri le Quick inquiry Where to buy Suppliers range | 2- (tert-Butoxycarbonyl oxyimino) phenyl acetonitri le is used as a reagent in the synthesis of phosphono methyl ornithine. Also used in the preparation of cholesterol-tagged natural fusion-protein-derived peptides with potent antiviral activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 58632-95-4. Pack Sizes: 5g, 10g. Molecular Formula: C13H14N2O3. US Biological Life Sciences. | Worldwide |
3-O-Acetyl-26-hydroxy Cholesterol Quick inquiry Where to buy Suppliers range | Intermediate in the production of cholesterol metabolites. Group: Biochemicals. Alternative Names: Cholest-5-ene-3 β,26-diol 3-acetate; (3 β)-Cholest-5-ene-3,26-diol 3-Acetate. Grades: Highly Purified. CAS No. 50681-37-3. Pack Sizes: 2mg. US Biological Life Sciences. | Worldwide |
3-O-Acetyl Ezetimibe Quick inquiry Where to buy Suppliers range | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L4) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4S)- 3-[(3S)-3-(acetyloxy)-3-(4-fluorophenyl)propyl]-1-(4-fluorophenyl)-4-(4-hydroxyphenyl)-2-Azetidinone. Grades: > 95%. CAS No. 190448-46-5. Molecular formula: C26H23F2NO4. Mole weight: 451.47. | |
3-O-Acetyl Ezetimibe 2,3,4-Tri-O-acetyl- β-D-glucuronide Methyl Ester Quick inquiry Where to buy Suppliers range | Intermediate in the preparation of Phase-II metabolites of Ezetimibe. Glucuronide azetidinone cholesterol absorption inhibitor. Group: Biochemicals. Alternative Names: 4-[(2S,3R)-3-[(3S)-3-(Acetyloxy)-3-(4-fluorophenyl)propyl]-1-(4-fluorophenyl)-4-oxo-2-azetidinyl]phenyl β-D-Glucopyranosiduronic Acid Methyl Ester 2,3,4-Triacetate. Grades: Highly Purified. CAS No. 190448-56-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
3-O-Acetyl Ezetimibe-d4 2,3,4-Tri-O-acetyl- β-D-glucuronide Methyl Ester Quick inquiry Where to buy Suppliers range | Labeled intermediate in the preparation of Phase-II metabolites of Ezetimibe. Glucuronide azetidinone cholesterol absorption inhibitor. Group: Biochemicals. Alternative Names: 4-[(2S,3R)-3-[(3S)-3-(Acetyloxy)-3-(4-fluorophenyl)propyl]-1-(4-fluorophenyl-d4)-4-oxo-2-azetidinyl]phenyl β-D-Glucopyranosiduronic Acid Methyl Ester 2,3,4-Triacetate. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
5α-Bromo-6,19-epoxycholestanol 3-Acetate Quick inquiry Where to buy Suppliers range | Intermediate in the chemical synthesis of cholesterol derivatives, and substrate for producing androsterone derivatives via bacterial steroid biotransformation. Group: Biochemicals. Alternative Names: (3 β,5α,6 β)-. Grades: Highly Purified. CAS No. 1258-07-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
5-Bromo-5α-cholestane-3,6-diol 3-Acetate Quick inquiry Where to buy Suppliers range | Intermediate in the production of cholesterol derivatives. Group: Biochemicals. Alternative Names: 3 β-Acetoxy-5-bromo-5α-cholestan-6 β-ol. Grades: Highly Purified. CAS No. 1258-35-1. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
Acetyl coenzyme A Quick inquiry Where to buy Suppliers range | Acetyl coenzyme A is the precursor to HMG CoA, an essential component in the synthesis of cholesterol and ketone. Synonyms: Acetyl-CoA; S-Acetyl coenzyme A; AcCoA; Coenzyme A, S-acetate; S-acetyl-CoA. CAS No. 72-89-9. Molecular formula: C23H38N7O17P3S. Mole weight: 809.57. | |
Acetyl coenzyme A sodium salt Quick inquiry Where to buy Suppliers range | Acetyl coenzyme A sodium salt, a pivotal molecule in the biomedical industry, is widely utilized in fatty acid and cholesterol biosynthesis, as well as the citric acid cycle. Its role in drug and toxin metabolism and breakdown in the body is also noteworthy. Besides, it contributes to treating metabolic disorders such as diabetes, obesity, and cancer. Its multifaceted functions make it a molecule of great scientific significance. Synonyms: Acetyl CoA. Grades: 90%. CAS No. 102029-73-2. Molecular formula: C23H38N7O17P3S·xNa. Mole weight: 809.57 (free acid). | |
AS-186c Quick inquiry Where to buy Suppliers range | AS-186c is an acyl-CoA: cholesterol acyltransferase (ACAT) inhibitor produced by Penicillum asperosporum KY1635. The IC50 for inhibiting ACAT was 11.5 μmol/L. Synonyms: 1-(7-{2-[2,6-dihydroxy-3-(3-methylbut-2-en-1-yl)benzoyl]-3-hydroxy-5-methylphenyl}-8,12-dihydroxy-4-methoxy-10-methyl-5-oxo-7,8-dihydro-5H-dibenzo[b,h][1,5]dioxonin-3-yl)-3-methylbutyl acetate. Molecular formula: C43H46O12. Mole weight: 754.82. | |
AS-186d Quick inquiry Where to buy Suppliers range | AS-186d is an acyl-CoA: cholesterol acyltransferase (ACAT) inhibitor produced by Penicillum asperosporum KY1635. The IC50 for inhibiting ACAT was 12.4 μmol/L. Synonyms: 1-(8,12-dihydroxy-7-{3-hydroxy-2-[6-hydroxy-3-(1-hydroxy-3-methylbutyl)-2-methoxybenzoyl]-5-methylphenyl}-4-methoxy-10-methyl-5-oxo-7,8-dihydro-5H-dibenzo[b,h][1,5]dioxonin-3-yl)-3-methylbutyl acetate. Molecular formula: C44H50O13. Mole weight: 786.86. | |
Berberine chloride hydrate Quick inquiry Where to buy Suppliers range | The plant-based alkaloid berberine has potential therapeutic applications for breast cancer, although a better understanding of the genes and cellular pathways regulated by this compound is needed to define the mechanism of its action in cancer treatment. In this review, the molecular targets of berberine in various cancers, particularly breast cancer, are discussed. Berberine was shown to be effective in inhibiting cell proliferation and promoting apoptosis in various cancerous cells. Some signaling pathways affected by berberine, including the MAP (mitogen-activated protein) kinase and Wnt/β-catenin pathways, are critical for reducing cellular migration and sensitivity to various growth factors. Treatment with BBR(Berberine) in rats on the atherogenic diet reduced plasma total cholesterol and nonHDL cholesterol levels by 29%-33% and 31%-41%, respectively, with no significant differences being observed among the three doses. Berberine induced both apoptotic and autophagic death of HepG2 cells, which was associated with a significant activation of AMPK and an increased expression of the inactive form of acetyl-CoA carboxylase (ACC). Berberine did not show major effects on viability of HEK-293 embryonic kidney and HCT116 colon carcinoma cells and was not toxic in concentrations up to 20 μM. Berberine inhibited β-catenin transcriptional activity and attenuated anchorage-independent growth. As a result of berberine treatment, cellular levels of active β-catenin were reduced concomitant with an increase in the expression of E-cadherin. Synonyms: Natural Yellow 18. Grades: >98%. CAS No. 141433-60-5. Molecular formula: C20H18ClNO4. Mole weight: 371.81. | |
Cancer Hydrolase KIAA1363 Inhibitor, JW480 (2-Isopropylphenyl-2- (2-naphthyl) ethylcarbamate, AADACL1 Inhibitor, Arylacetamide Deacetylase-Like 1 Inhibitor, NCEH1 Inhibitor, Neutral Cholesterol Ester Hydrolase 1 Inhibitor) Quick inquiry Where to buy Suppliers range | A membrane-permeable, highly potent and selective inhibitor against the 2-acetyl MAGE (monoakylglycerol ether) hydrolase KIAA1363/AADACL1 of both human (IC50=12nM; PC3 lysate) and murine (IC50=20nM; brain membrane samples) origin, with no significant effect toward other PC3 or murine brain serine hydrolase activities, including HSL, FAAH, and AChE. Readily crosses blood-brain barrier in mice and effectively suppresses PC3-derived tumor growth in mice in vivo (by 56% on day 33; 80mg/kg/day; o.g.). Also inhibits blood carboxylesterase. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
Cholesteryl acetate Quick inquiry Where to buy Suppliers range | Cholesteryl acetate - Product ID: NST-10-92. Category: Sterols. Alternative Names: Acebrochol, Cholesterol, Cholesterin. Purity: 98%. Test method: HPLC. CAS No. 604-35-3. Pack Sizes: 5g, 10g, 25g, 50g. Appearance: White to beige colored powder. Molecular formula: C29H48O2. Mole weight: 428.7. Storage: +2 +8 °C. | |
Ezetimibe Diacetate Quick inquiry Where to buy Suppliers range | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L5) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4S)-3-[(3S)-3-(Acetyloxy)-3-(4-fluorophenyl)propyl]-4-[4-(acetyloxy)phenyl]-1-(4-fluorophenyl)-2-azetidinone. Grades: > 95%. CAS No. 163380-20-9. Molecular formula: C28H25F2NO5. Mole weight: 493.51. | |
FR901512 Quick inquiry Where to buy Suppliers range | FR901512, a new specific inhibitor of HMG-CoA reductase, is isolated from the culture of an agonomycetous fungus No. 14919. FR901512 inhibits cholesterol synthesis from [14C] acetate in Hep G2 cells. Synonyms: 6-Heptenoic acid, 7-[(6R,8S)-8-(acetyloxy)-5,6,7,8-tetrahydro-2,6-dimethyl-1-naphthalenyl]-3,5-dihydroxy-, (3R,5S,6E)-; (3R,5S,E)-7-((6R,8S)-8-acetoxy-2,6-dimethyl-5,6,7,8-tetrahydronaphthalen-1-yl)-3,5-dihydroxyhept-6-enoic acid. CAS No. 151606-25-6. Molecular formula: C21H28O6. Mole weight: 376.44. | |
GW 501516 Quick inquiry Where to buy Suppliers range | An experimental drug meant to control lipids and increase the level of HDL, or good cholesterol, in the bloodstream. A cell-permeable, thiazolyl compound that acts as a potent, high affinity, PPARδ agonist. Exhibits selectivity for PPARδ compared to PPARα and PPARγ. Does not exibit any activity against other nuclear or non-nuclear receptors. Reported to increase cholesterol efflux and ABAC1 expression in macrophages, fibroblasts, and intestinal cells. Group: Biochemicals. Alternative Names: 2- [2-Methyl-4- [ [ [4-methyl-2- [4- (trifluoromethyl) phenyl] -5-thiazolyl] methyl] thio] phenoxy] acetic Acid; Methyl-methyl-trifluoromethylphenyl-thiazolyl-methylsulfanyl-phenoxy-acetic Acid; GW 1516; Endurobol. Grades: Highly Purified. CAS No. 317318-70-0. Pack Sizes: 10mg, 50mg. Molecular Formula: C??H??F?NO?S?, Molecular Weight: 453.5. US Biological Life Sciences. | Worldwide |
Lalistat 1 Quick inquiry Where to buy Suppliers range | Lalistat 1 is a lysosomal acid lipase inhibitor with IC50 value of 68 nM. It can block LAL-mediated lipid hydrolysis of acetylated LDL and reduce efflux of cholesterol from lipid-loaded cells. Synonyms: 4-(Piperidin-1-yl)-1,2,5-thiadiazol-3-yl morpholine-4-carboxylate. Grades: ≥98% by HPLC. CAS No. 501104-16-1. Molecular formula: C12H18N4O3S. Mole weight: 298.36. | |
Lapaquistat acetate Quick inquiry Where to buy Suppliers range | Lapaquistat acetate, also referred as TAK475, is a squalene synthase inhibitor. As a cholesterol-lowering drug, Lapaquistat acetate decreased plasma cholesterol and triglyceride levels, by lowering lipoproteins containing apoB100. Uses: A novel squalene synthase inhibitor. Synonyms: 2-[1-[2-[(3R,5S)-1-(3-acetyloxy-2,2-dimethylpropyl)-7-chloro-5-(2,3-dimethoxyphenyl)-2-oxo-5H-4,1-benzoxazepin-3-yl]acetyl]piperidin-4-yl]acetic acid; (1-(2-(1-(2-carboxyoxy-1,1-dimethylethyl)-7-chloro-5-(2,3-dimethoxyphenyl)-2-oxo-1,2,3,5-tetrahydrobenzo(e)(1,4)oxazepin-3-yl)acetyl)piperidin-4-yl)acetic acid; 1-((1-(3-acetoxy-2,2-dimethylpropyl)-7-chloro-5-(2,3-dimethoxyphenyl)-2-oxo-1,2,3,5-tetrahydro-4,1-benzoxazepin-3-yl)acetyl)piperidine-4-acetic acid; lapaquistat; TAK 475; TAK-475; TAK475. Grades: >98%. CAS No. 189060-13-7. Molecular formula: C33H41ClN2O9. Mole weight: 645.14. | |
Laropiprant Quick inquiry Where to buy Suppliers range | a drug used in combination with niacin to reduce blood cholesterol (LDL and VLDL) that is no longer sold. Uses: A potent, selective dp1 receptor antagonist. Synonyms: (3R)-4-[(4-chlorophenyl)methyl]-7-fluoro-1,2,3,4-tetrahydro-5-(methylsulfonyl)-cyclopent[b]indole-3-acetic acid. Grades: > 95%. CAS No. 571170-77-9. Molecular formula: C21H19ClFNO4S. Mole weight: 435.91. | |
Palmitoyl eicosapentaenoyl Phosphatidylcholine-d9 Quick inquiry Where to buy Suppliers range | Palmitoyl eicosapentaenoyl Phosphatidylcholine-d9 is labelled Palmitoyl eicosapentaenoyl Phosphatidylcholine (P156900) which is a possible Cholesterol Acetyltransferase inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C44H69D9NO8P, Molecular Weight: 789.12. US Biological Life Sciences. | Worldwide |
Purpactin A Quick inquiry Where to buy Suppliers range | Purpactin A is a cholesterol acyltransferase (ACAT) inhibitor produced by Pen. purpurogenum FO-6. Synonyms: 1'-O-acetylpenicillide; Vermixocin B. Molecular formula: C23H26O7. Mole weight: 414.45. | |
Purpactin B Quick inquiry Where to buy Suppliers range | Purpactin B is a cholesterol acyltransferase (ACAT) inhibitor produced by Pen. purpurogenum FO-6. Synonyms: 1-[2'-(hydroxymethyl)-4-methoxy-4'-methyl-3,6'-dioxo-3h-spiro[1-benzofuran-2,1'-cyclohexa[2,4]dien]-5-yl]-3-methylbutyl acetate. CAS No. 133806-60-7. Molecular formula: C23H26O7. Mole weight: 414.45. | |
Pyripyropene A Quick inquiry Where to buy Suppliers range | Pyripyropene A is a powerful acyl-CoA: cholesterol acyltransferase 2 (ACAT2) inhibitor produced by the fungus Aspergillus fumigatus FO 1289. It inhibits acyl-CoA: cholesterol acyltransferase with an IC50 of 58 nmol/L. Synonyms: (3S,4R,4aR,6S,6aS,12R,12aS,12bS)-4-(acetoxymethyl)-12-hydroxy-4,6a,12b-trimethyl-11-oxo-9-(pyridin-3-yl)-1,3,4,4a,5,6,6a,12,12a,12b-decahydro-2H,11H-benzo[f]pyrano[4,3-b]chromene-3,6-diyl diacetate; (3S,4R,4aR,6S,6aS,12R,12aS,12bS)-4-(Acetoxymethyl)-12-hydroxy-4,6a,12b-trimethyl-11-oxo-9-(pyridin-3-yl)-1,2,3,4,4a,5,6,6a,11,12,12a,12b-dodecahydrobenzo[f]pyrano[4,3-b]chromene-3,6-diyl diacetate. Grades: ≥95%. CAS No. 147444-03-9. Molecular formula: C31H37NO10. Mole weight: 583.62. | |
Pyripyropene A ((+)-Pyripyropene A, PPPA, FO 1289A) Quick inquiry Where to buy Suppliers range | Antibiotic. Highly specific inhibitor of acyl-coenzyme A:cholesterol acetyltransferase 2 (ACAT2). Anti-angiogenic. Antiatherogenic and antiatherosclerotic agent. Shows cholesterol-lowering and atheroprotective activities. Group: Biochemicals. Alternative Names: (+)-Pyripyropene A, PPPA, FO 1289A. Grades: Highly Purified. CAS No. 147444-03-9. Pack Sizes: 250ug, 1mg. Molecular Formula: C31H37NO10, Molecular Weight: 583.6. US Biological Life Sciences. | Worldwide |
Pyripyropene B Quick inquiry Where to buy Suppliers range | Pyripyropene B is a powerful acyl-CoA: cholesterol acyltransferase 2 (ACAT2) inhibitor produced by the fungus Aspergillus fumigatus FO 1289. It inhibits acyl-CoA: cholesterol acyltransferase with an IC50 of 117 nmol/L. Synonyms: 2H,11H-Naphtho[2,1-b]pyrano[3,4-e]pyran-11-one,3,6-bis(acetyloxy)-1,3,4,4a,5,6,6a,12,12a,12b-decahydro-12-hydroxy-4,6a,12b-trimethyl-4-[(1-oxopropoxy)methyl]-9-(3-pyridinyl)-,(3S,4R,4aR,6S,6aS,12R,12aS,12bS)-. CAS No. 151519-44-7. Molecular formula: C32H39NO10. Mole weight: 597.65. | |
RVX-208 Quick inquiry Where to buy Suppliers range | RVX-208 is a potent inhibitor of BET bromodomains. RVX-208 functions by removing atherosclerotic plaque via reverse cholesterol transport (RCT). RVX-208 increases the production of ApoA-I in hepatocytes in vitro, and in vivo in monkeys and humans, which results in increased HDL-C, but the molecular target was not previously reported. Using binding assays and X-ray crystallography, we now show that RVX-208 selectively binds to bromodomains of the BET (Bromodomain and Extra Terminal) family, competing for a site bound by the endogenous ligand, acetylated lysine, and that this accounts for its pharmacological activity. siRNA experiments further suggest that induction of ApoA-I mRNA is mediated by BET family member BRD4. These data indicate that RVX-208 increases ApoA-I production through an epigenetic mechanism and suggests that BET inhibition may be a promising new approach to the treatment of atherosclerosis. Synonyms: RVX208; RVX 208; RVX-208; Apabetalone. Grades: >98%. CAS No. 1044870-39-4. Molecular formula: C20H22N2O5. Mole weight: 370.40. | |
Sbc-1107326 Quick inquiry Where to buy Suppliers range | SBC-110736 is an inhibitor of proprotein convertase subtilisin kexin type 9 (PCSK9). Study shows that it can lower cholesterol levels in mice. Synonyms: Sbc 1107326; Sbc1107326; N-[4-(2-Phenyl-4-p-tolyl-piperazine-1-carbonyl)-phenyl]-acetamide. Grades: ≥98%. CAS No. 1629166-02-4. Molecular formula: C26H27N3O2. Mole weight: 413.51. | |
Simvastatin EP Impurity B Quick inquiry Where to buy Suppliers range | An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: Acetyl simvastatin; 4'-Acetyl Simvastatin; Simvastatin Acetate; Simvastatin acetate ester; Simvastatin USP Related Compound B. Grades: 95%. CAS No. 145576-25-6. Molecular formula: C27H40O6. Mole weight: 460.62. | |
SPT Imidazopyridine 1 Quick inquiry Where to buy Suppliers range | SPT Imidazopyridine 1 is a potent serine palmitoyl transferase (SPT) inhibitor (IC50 = 5 nM) used for the treatment of type 2 diabetes and dyslipidemia. SPT Imidazopyridine 1 inhibits incorporation of 14C-serine into ceramide in dose manner, and lowers plasma ceramide levels in vivo. It also has the effect of increasing plasma HDL and reducing VLDL cholesterol levels in rats. Synonyms: SPT-IN-1; SPT IN 1; SPT Inhibitor 1; Imidazopyridine 1; 4-[6-(1-Oxoheptyl)imidazo[1,2-a]pyridin-8-yl]benzeneacetic acid; 2-[4-(6-heptanoylimidazo[1,2-a]pyridin-8-yl)phenyl]acetic acid; SPT-IN-1. Grades: ≥98%. CAS No. 1933533-18-6. Molecular formula: C22H24N2O3. Mole weight: 364.44. |