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100g Pack Size. Group: Bioactive Small Molecules, Biochemicals, Organics. Formula: C24H40O5. CAS No. 81-25-4. Prepack ID 25751419-100g. Molecular Weight 408.57. See USA prepack pricing.
Cholicacid
Cholicacid could inhibit the activity of cardiac myocytes by causing calcium overload, thereby leading to the sudden fetal death in ICP. Uses: Hypotensive. Synonyms: Colalin; Cholalic acid; cholate; Cholalin; Cholsaeure; 5β-cholanic acid-3α,7α,12α-triol. Grades: >98%. CAS No. 81-25-4. Molecular formula: C24H40O5. Mole weight: 408.58.
Cholicacid
Cholicacid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholicacid is orally active [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 81-25-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 1 g. Product ID: HY-N0324.
Cholicacid
Cholicacid. Synonyms: Cholalic Acid. CAS No. 81-25-4. Product ID: PE-0435. Molecular formula: C24H40O5. Mole weight: 408.32. Category: Dispersants. Product Keywords: Pharmaceutical Excipients; Excipients for Liquid Dosage Form; Cholicacid; Dispersion Excipients; Dispersants; C24H40O5; 81-25-4; 81-25-4. UNII: NA. Grade: Pharmceutical Excipients. Stability and Storage Conditions: Keep sealed and away from light in a cool and dry place. Source and Preparation: All kinds of cholicacids can be combined with glycine or taurine with peptide bonds to form various bile acids. The bile of pig, cow and sheep was hydrolyzed with cholecylanin and alkali, and the pH was adjusted to 3.0 with hydrochloric acid. The precipitates were extracted and washed to neutral, refined with ethanol and activated carbon, washed with glacial acetic acid, and recrystallized. There are several kinds of cholicacids due to the different number and location of hydroxyl groups. The main ones are 3, 7, 12-trihydroxycholicacid and deoxycholicacid (i.e. 3, 12-dihydroxycholicacid). Safety: This product is non-toxic, ADI 0-1.25MG/kg.
Cholicacid
Cholicacid. Synonyms: Cholalic Acid. CAS No. 81-25-4. Product ID: PE-0570. Molecular formula: C24H40O5. Mole weight: 408.32. Category: Polymer Solid Dispersant; Emulsifier. Product Keywords: Excipients for Liquid Dosage Form; Emulsifier Excipients; PE-0570; Cholicacid; Polymer Solid Dispersant; Emulsifier; C24H40O5; 81-25-4. UNII: NA. Grade: Pharmceutical Excipients. Stability and Storage Conditions: Keep sealed and away from light in a cool and dry place. Source and Preparation: All kinds of cholicacids can be combined with glycine or taurine with peptide bonds to form various bile acids. The bile of pig, cow and sheep was hydrolyzed with cholecylanin and alkali, and the pH was adjusted to 3.0 with hydrochloric acid. The precipitates were extracted and washed to neutral, refined with ethanol and activated carbon, washed with glacial acetic acid, and recrystallized. There are several kinds of cholicacids due to the different number and location of hydroxyl groups. The main ones are 3, 7, 12-trihydroxycholicacid and deoxycholicacid (i.e. 3, 12-dihydroxycholicacid). Safety: This product is non-toxic, ADI 0~1.25MG/kg.
CholicAcid
Choleretic produced by and isolated from liver cells. Group: Biochemicals. Alternative Names: (3α,5 β, 7α12α)-3, 7, 12-Trihydroxy-cholan-24-oic Acid; 17 β-(1-Methyl-3-carboxy-propyl)etiocholane-3α, 7α, 12α-triol;5 β-CholicAcid; Cholalic Acid; Cholalin; Colalin; NSC-6135. Grades: Highly Purified. CAS No. 81-25-4. Pack Sizes: 25g, 50g, 100g, 250g, 500g, 1Kg. Molecular Formula: C24H40O5, Molecular Weight: 408.57. US Biological Life Sciences.
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CholicAcid
CholicAcid - Product ID: NST-10-206. Category: sterols. Alternative Names: Cholalic acid, Cholalin, Cholbam, Colalin, Kolbam, Orphacol. Purity: 98%. Test method: HPLC. CAS No. 81-25-4. Pack Sizes: 25g, 50g, 125g, 250g. Appearance: White Powder. Molecular formula: C24H40O5. Mole weight: 408.57. Storage: +2 +8 °C.
Cholicacid-24-13C
Cholicacid-24-13C. Group: Biochemicals. Grades: Highly Purified. CAS No. 52886-36-9. Pack Sizes: 100mg, 250mg, 500mg. Molecular Formula: C24H40O5. US Biological Life Sciences.
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Cholicacid 7-sulfate
Cholicacid 7-sulfate (7-Sulfocholicacid), a metabolite of Cholicacid, is a Takeda G-protein receptor 5 (TGR5) agonist. Cholicacid 7-sulfate can increase Tgr5 expression and induce GLP-1 secretion [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 7-Sulfocholicacid. CAS No. 60320-05-0. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-126855.
Cholicacid-d4
Cholicacid-d 4 is the deuterium labeled Cholicacid. Cholicacid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 116380-66-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0324S.
CholicAcid-d4
CholicAcid-d4 is a labelled analog of Cholicacid (C432600) which is a choleretic produced by, and isolated from liver cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 116380-66-6. Pack Sizes: 1mg, 5mg. Molecular Formula: C24H36D4O5. US Biological Life Sciences.
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CholicAcid-d5
CholicAcid-d5. Group: Biochemicals. Alternative Names: (3α,5 β, 7α12α)-3, 7, 12-Trihydroxy-cholan-24-oic Acid-d5; 17 β-(1-Methyl-3-carboxy-propyl)etiocholane-3α, 7α, 12α-triol-d5;5 β-CholicAcid-d5; Cholalic Acid-d5; Cholalin-d5; Colalin-d5; NSC-6135-d5. Grades: Highly Purified. CAS No. 53007-09-3. Pack Sizes: 1mg. Molecular Formula: C24H35D5O5, Molecular Weight: 413.6. US Biological Life Sciences.
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CholicAcid Methyl Ester
Protected CholicAcid. Group: Biochemicals. Alternative Names: (3α,5 β, 7α, 12α)-3, 7, 12-Trihydroxy-cholan-24-oic Acid Methyl Ester; Methyl 3α, 7α, 12α-Trihydroxy-5 β-cholanoate; Methyl cholate; NSC 126794. Grades: Highly Purified. CAS No. 1448-36-8. Pack Sizes: 1g. US Biological Life Sciences.
Cholicacid sodium is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholicacid sodium is orally active [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Sodium cholate. CAS No. 361-09-1. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-N0324A.
Cholicacid sodium salt
100g Pack Size. Group: Biochemicals, Diagnostic Raw Materials. Formula: C24H39NaO5. CAS No. 361-09-1. Prepack ID 15562390-100g. Molecular Weight 430.55. See USA prepack pricing.
Cholicacid sodium salt
Cholicacid sodium salt. Group: Biochemicals. Grades: Highly Purified. CAS No. 361-09-1. Pack Sizes: 10g, 25g, 50g, 100g, 250g. Molecular Formula: C24H39NaO5. US Biological Life Sciences.
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Cholicacid sodium salt hydrate
100g Pack Size. Group: Biochemicals, Detergents, Research Organics & Inorganics. Formula: C24H39NaO5 · xH2O. CAS No. 73163-53-8. Prepack ID 13237653-100g. Molecular Weight 448.57. See USA prepack pricing.
12-Hydroxy TaurolithocholicAcid-2,2,3,4,4-d5 O-3-Glucuronide Dipotassium Salt
12-Hydroxy TaurolithocholicAcid-2,2,3,4,4-d5 O-3-Glucuronide Dipotassium Salt is a labelled analogue of 12-Hydroxy TaurolithocholicAcid O-3-Glucuronide Dipotassium Salt (H954095), an impurity of CholicAcid (C432600), which is a choleretic produced by and isolated from liver cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C32H46D5NO12S.2K, Molecular Weight: 757.04. US Biological Life Sciences.
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12-Hydroxy TaurolithocholicAcid-2,2,3,4,4-d5 Sulfate Disodium Salt
12-Hydroxy TaurolithocholicAcid-2,2,3,4,4-d5 Sulfate Disodium Salt is a laballed analogue of 2-Hydroxy TaurolithocholicAcid Sulfate Disodium Salt (H954090), an impurity of CholicAcid (C432600), which is a choleretic produced by and isolated from liver cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C26H38D5NNa2O9S2, Molecular Weight: 628.76. US Biological Life Sciences.
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12-Hydroxy TaurolithocholicAcid O-3-Glucuronide Dipotassium Salt
12-Hydroxy TaurolithocholicAcid O-3-Glucuronide Dipotassium Salt is an impurity of CholicAcid, a choleretic produced by and isolated from liver cells. Synonyms: (3α,5β,12α)-12-Hydroxy-24-oxo-24-[(2-sulfoethyl)amino]cholan-3-yl β-D-Glucopyranosiduronic Acid Dipotassium Salt; Cholane β-D-Glucopyranosiduronic Acid Derivative. CAS No. 75672-37-6. Molecular formula: C32H51NO12S 2K. Mole weight: 752.01.
12-Hydroxy TaurolithocholicAcid O-3-Glucuronide Dipotassium Salt
12-Hydroxy TaurolithocholicAcid O-3-Glucuronide Dipotassium Salt is an impurity of CholicAcid (C432600), a choleretic produced by and isolated from liver cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 75672-37-6. Pack Sizes: 1mg, 2mg. Molecular Formula: C32H51NO12S.2K, Molecular Weight: 752.01. US Biological Life Sciences.
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12-Hydroxy TaurolithocholicAcid Sulfate Disodium Salt
2-Hydroxy TaurolithocholicAcid Sulfate Disodium Salt is an impurity of CholicAcid (C432600), a choleretic produced by and isolated from liver cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 66874-07-5. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C26H43NNa2O9S2. US Biological Life Sciences.
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3-?Oxocholicacid
3-Oxocholicacid is an oxo-bile acid metabolite and also a major degradation product from cholic by C. perfringens in the intestine. 3-Oxocholicacid is steroid acid found predominantly in bile of mammals [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: 3-Dehydrocholicacid. CAS No. 2304-89-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-N7387.
Allocholicacid
Allocholicacid. Group: Biochemicals. Alternative Names: 3-a,7-a,12-a-Trihydroxy-5-a-cholanoic acid; 5a-Cholicacid. Grades: Highly Purified. CAS No. 2464-18-8. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C24H40O5. US Biological Life Sciences.
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Allocholicacid
Allocholicacid is a bile acid metabolized from animals. Allocholicacid is also a precursor to petromyzonol. Synonyms: 3alpha,7alpha,12alpha-Trihydroxy-5alpha-cholan-24-oic acid; 5alpha-cholicacid; 5α-cholanic acid-3α,7α,12α-triol. Grades: >99%. CAS No. 2464-18-8. Molecular formula: C24H40O5. Mole weight: 408.57.
Allocholicacid
Allocholicacid is a typically fetal bile acid found in vertebrates and reappears during liver regeneration and carcinogenesis, besides it is also a conjugate acid of allocholate and an isomer of cholicacid. Allocholicacid is a potent and specific stimulant of the adult olfactory system, it has a role as a marine metabolite, a rat metabolite and a human metabolite [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 2464-18-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-125934.
Apocholicacid
ApocholicAcid is originally produced from CholicAcid which is a choleretic produced by and isolated from liver cells. Synonyms: 3alpha,12alpha-Dihydroxy-5beta-chol-8(14)-en-24-oic acid; 5β,8(14)-Cholen-24-oic acid-3α,12α-diol; 3α,12α-Dihydroxy-5β,8(14)-cholen-24-oic acid. Grades: >99%. CAS No. 641-81-6. Molecular formula: C24H38O4. Mole weight: 390.56.
DehydrocholicAcid
DehydrocholicAcid is a derivative of CholicAcid and manufactured by the oxidation of cholicacid. It is produced by choleretic and isolated from liver cells. It acts as a hydrocholeretic, increasing bile output to clear increased bile acid load. Uses: Dehydrocholic acts as a hydrocholeretic, increasing bile output to clear increased bile acid load. Synonyms: Decholin; Dehystolin; Oxycholin; Ketocholanic acid; Felacrinos; Sanocholen; 3,7,12-Trioxocholanic acid. Grades: >98%. CAS No. 81-23-2. Molecular formula: C24H34O5. Mole weight: 402.52.
DeoxycholicAcid-2,2,3,4,4-d5 3-O- β-D-Glucuronide Disodium Salt
DeoxycholicAcid-2,2,3,4,4-d5 3-O- β-D-Glucuronide Disodium Salt is a labelled analogue of DeoxycholicAcid 3-O- β-D-Glucuronide Disodium Salt (D232720), an impurity of CholicAcid (C432600), which is a choleretic produced by and isolated from liver cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 2mg. Molecular Formula: C30H41D5Na2O10, Molecular Weight: 617.69. US Biological Life Sciences.
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DeoxycholicAcid 3-O- β-D-Glucuronide Disodium Salt
DeoxycholicAcid 3-O- β-D-Glucuronide Disodium Salt is an impurity of CholicAcid (C432600), a choleretic produced by and isolated from liver cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 59274-67-8. Pack Sizes: 1mg, 2mg. Molecular Formula: C30H46Na2O10, Molecular Weight: 612.66. US Biological Life Sciences.
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DeoxycholicAcid 3-O-β-D-Glucuronide Disodium Salt
DeoxycholicAcid 3-O-β-D-Glucuronide Disodium Salt is an impurity of CholicAcid, a choleretic produced by and isolated from liver cells. Synonyms: (3α,5β,12α)-23-Carboxy-12-hydroxy-24-norcholan-3-yl-β-D-glucopyranosiduronic Acid Disodium Salt. Grades: 98%. CAS No. 59274-67-8. Molecular formula: C30H46Na2O10. Mole weight: 612.66.
DeoxycholicAcid-d5 3-O-Sulfate Disodium Salt
DeoxycholicAcid-d5 3-O-Sulfate Disodium Salt is a labelled impurity of CholicAcid (C432600), it is produced and isolated from liver cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C24H33D5Na2O7S, Molecular Weight: 521.63. US Biological Life Sciences.
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GlycocholicAcid-d5
The product of conjugation of cholicacid with glycine; chief ingredient of the bile of herbivorous animals. In the weakly alkaline bile fluid glycocholicacid exists as the sodium salt. Group: Biochemicals. Alternative Names: N-[(3α,5 β, 7α, 12α)-3, 7, 12-?rihydroxy-24-oxocholan-24-yl]glycine-d5; N-Choloylglycine. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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GlycocholicAcid Hydrate
Labeled GlycocholicAcid. The product of conjugation of cholicacid with glycine; chief ingredient of the bile of herbivorous animals. In the weakly alkaline bile fluid glycocholicacid exists as the sodium salt. Group: Biochemicals. Alternative Names: N-[(3α,5 β, 7α, 12α)-3, 7, 12-?rihydroxy-24-oxocholan-24-yl]glycine Hydrate; N-Choloylglycine. Grades: Highly Purified. CAS No. 475-31-0. Pack Sizes: 1g. US Biological Life Sciences.
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Icomidocholicacid
Icomidocholicacid (Aramchol) is a lipid molecule synthesized from cholicacid and arachidic acid. Icomidocholicacid is an orally active SCD1 inhibitor and cholesterol solubilizer with antifibrotic effects. Icomidocholicacid can reduce liver fat content, dissolve cholesterol crystals and prevent gallstone formation. Icomidocholicacid can be used in the study of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Aramchol; C20-FABAC. CAS No. 246529-22-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19796.
LithocholicAcid
A cholicacid derivative as TGR5 modulator. Found in ox bile, human bile, rabbit bile, and in ox and pig gallstones. Group: Biochemicals. Alternative Names: (3α,5 β)-3-Hydroxycholan-24-oic Acid; 17 β - (1-Methyl-3-carboxypropyl) etiocholan-3α -ol; 3-Hydroxycholan-24-oic Acid; 3α-Hydroxy-5 β-cholan-24-oate; 3α-Hydroxy-5 β-cholan-24-oic Acid; 3α-Hydroxy-5 β-cholanic Acid; 3α-Hydroxy-5 β-cholanoic Acid; 3α-Hydroxycholanic Acid; NSC 683770. Grades: Highly Purified. CAS No. 434-13-9. Pack Sizes: 1g. US Biological Life Sciences.
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LithocholicAcid
A cholicacid derivative as TGR5 modulator. Found in ox bile, human bile, rabbit bile, and in ox and pig gallstones. Group: Steroidal compounds. Alternative Names: 3α-Hydroxy-5β-cholanic acid. CAS No. 434-13-9. Molecular formula: C24H40O3. Mole weight: 376.57. Appearance: White to off-white powder. Purity: 0.98. IUPACName: (4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-Hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid. Canonical SMILES: CC (CCC (=O)O)C1CCC2C1 (CCC3C2CCC4C3 (CCC (C4)O)C)C. Density: 1.0454 g/cm³. ECNumber: 207-099-1. Catalog: ACM434139.
LithocholicAcid 24-Ac-O-β-D-Glucuronide
LithocholicAcid 24-Ac-O-β-D-Glucuronide is an impurity of LithocholicAcid (L469180), a cholicacid derivative as TGR5 modulator. Found in ox bile, human bile, rabbit bile, and in ox and pig gallstones. Synonyms: 1-[(3α,5β)-3-Hydroxycholan-24-oate] β-D-Glucopyranuronic Acid. CAS No. 142780-61-8. Molecular formula: C30H48O9. Mole weight: 552.7.
LithocholicAcid 3-O-Glucuronide
LithocholicAcid 3-O-Glucuronide is an impurity of LithocholicAcid, a cholicacid derivative as TGR5 modulator. Found in ox bile, human bile, rabbit bile, and in ox and pig gallstones. Synonyms: (3α,5β)-23-Carboxy-24-norcholan-3-yl β-D-Glucopyranosiduronic Acid; LithocholicAcid 3-Glucuronide. Grades: 98%. CAS No. 75239-91-7. Molecular formula: C30H48O9. Mole weight: 552.7.
LithocholicAcid-d4
A labeled cholicacid derivative as TGR5 modulator. Found in ox bile, human bile, rabbit bile, and in ox and pig gallstones. Group: Biochemicals. Alternative Names: (3α,5 β)-3-Hydroxycholan-24-oic Acid-d4; 17 β - (1-Methyl-3-carboxypropyl) etiocholan-3α -ol-d4; 3-Hydroxycholan-24-oic Acid-d4; 3α-Hydroxy-5 β-cholan-24-oate-d4; 3α-Hydroxy-5 β-cholan-24-oic Acid-d4; 3α-Hydroxy-5 β-cholanic Acid-d4; 3α-Hydroxy-5 β-cholanoic Acid-d4; 3α-Hydroxycholanic Acid-d4; NSC 683770-d4. Grades: Highly Purified. CAS No. 83701-16-0. Pack Sizes: 1mg. US Biological Life Sciences.
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LithocholicAcid-d5
A labelled cholicacid derivative as TGR5 modulator. Found in ox bile, human bile, rabbit bile, and in ox and pig gallstones. Group: Biochemicals. Alternative Names: (3α,5 β)-3-Hydroxycholan-24-oic Acid-d5; 17 β - (1-Methyl-3-carboxypropyl) etiocholan-3α -ol-d5; 3-Hydroxycholan-24-oic Acid-d5; 3α-Hydroxy-5 β-cholan-24-oate-d5; 3α-Hydroxy-5 β-cholan-24-oic Acid-d5; 3α-Hydroxy-5 β-cholanic Acid-d5; 3α-Hydroxy-5 β-cholanoic Acid-d5; 3α-Hydroxycholanic Acid-d5; NSC 683770-d5. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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Nor CholicAcid
A novel bile acid, an analogue of Cholicacid. Group: Biochemicals. Alternative Names: (3α,5 β, 7α, 12α)-3, 7, 12-Trihydroxy-24-norcholan-23-oic Acid; 3α, 7α, 12α-Trihydroxy- 23-nor-5 β-cholanic Acid; 23-NorcholicAcid; 24-NorcholicAcid; 3α, 7α, 12α-Trihydroxy-24-nor-5 β-cholan-23-oic Acid; NorcholicAcid. Grades: Highly Purified. CAS No. 60696-62-0. Pack Sizes: 100mg. US Biological Life Sciences.
SulfolithocholicAcid is an derivative of LithocholicAcid (L469180), a cholicacid derivative and TGR5 modulator found in ox bile, human bile, rabbit bile, and in ox and pig gallstones. Group: Biochemicals. Alternative Names: 3α-Sulfate-5 β-cholan-24-oic Acid Trimethylamine Salt; LithocholicAcid 3-O-Sulfate Trimethylamine Salt ; LithocholicAcid 3α-Sulfate Trimethylamine Salt; (3α,5 β)-3-(Sulfooxy)-cholan-24-oic Acid Trimethylamine Salt. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Choleretic; Its sodium salt is a bile salt formed in the liver by conjugation of cholicacid with taurine that is involved in the emulsification of lipids used to solubilize lipids and membrane-bound proteins. Uses: Used to solubilize lipids and membrane-bound proteins. Synonyms: 2-[[(3α, 5β, 7α, 12α)-3, 7, 12-trihydroxy-24-oxocholan-24-yl]amino]-ethanesulfonic acid, monosodium salt. Grades: ≥98%. CAS No. 345909-26-4. Molecular formula: C26H46NNaO8S. Mole weight: 555.70.
(3α,5R,6 β,20S)-6-Methoxy-3,5-cyclopregnane-30-methanol 4-Methylbenzenesulfonate is a tosylated derivative that have been utilized in the biosynthetic studies of cholicacids and vitamin D3 derivatives. Group: Biochemicals. Alternative Names: (20S)-6 β -Methoxy-20- (p-toluenesulfonyloxy methyl ) -3 α , 5-cyclo-5 α -pregnane; (3α,5R,6 β,20S)-6-Methoxy-3,5-cyclopregnane-20-methanol 20- (4-Methyl Benzene sulfonate) . Grades: Highly Purified. CAS No. 51231-24-4. Pack Sizes: 2.5mg. US Biological Life Sciences.
This enzyme forms part of the rat peroxisomal multifunctional enzyme perMFE-2, which also exhibits a dehydrogenase activity. The enzyme is involved in the β-oxidation of the cholesterol side chain in the cholic-acid-biosynthesis pathway. Group: Enzymes. Synonyms: 46 kDa hydratase 2; (24R,25R)-3α,7α,12α,24-tetrahydroxy-5β-cholestanoyl-CoA hydro-lyase. Enzyme Commission Number: EC 4.2.1.107. CAS No. 152787-68-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4946; 3α,7α,12α-trihydroxy-5β-cholest-24-enoyl-CoA hydratase; EC 4.2.1.107; 152787-68-3; 46 kDa hydratase 2; (24R,25R)-3α,7α,12α,24-tetrahydroxy-5β-cholestanoyl-CoA hydro-lyase. Cat No: EXWM-4946.
(3 β,5α,6 β,20S)-6-Methoxy-3,5-cyclopregnane-20-methanol is a functionalized steroid used as a tool in the biosynthetic studies of cholicacids and vitamin D3 derivatives. Group: Biochemicals. Alternative Names: (3α,5R,6 β,20S)-6-Methoxy-3,5-cyclopregnane-20-methanol. Grades: Highly Purified. CAS No. 51231-23-3. Pack Sizes: 2.5mg. US Biological Life Sciences.
(3 β,5 β, 7α, 12α)-3-(Formyloxy)-7, 12-dihydroxycholan-24-oic Acid Methyl Ester is an intermediate in the synthesis 3 β-CholicAcid (C432605), a possible progesterone (P755900) metabolite. Group: Biochemicals. Alternative Names: Methyl 3 β-(Formyloxy)-7α,12α-dihydroxycholanate. Grades: Highly Purified. CAS No. 42921-40-4. Pack Sizes: 250mg. US Biological Life Sciences.
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5β-CHOLANIC ACID-3α, 7α, 12α-TRIOL SODIUM SALT
5β-CHOLANIC ACID-3α, 7α, 12α-TRIOL SODIUM SALT. Group: Biochemicals. Alternative Names: CHOLICACID SODIUM SALTSODIUM CHOLATE. CAS No. 73163-53-8. US Biological Life Sciences.
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5β-cholestane-3α,7α-diol 12α-hydroxylase
A heme-thiolate protein (P-450). This is the key enzyme in the biosynthesis of the bile acidcholicacid (3α,7α,12α-trihydroxy-5β-cholanoic acid). The activity of this enzyme determines the biosynthetic ratio between cholicacid and chenodeoxycholicacid. The enzyme can also hydroxylate the substrate at the 25 and 26 position, but to a lesser extent. Group: Enzymes. Synonyms: 5β-cholestane-3α,7α-diol 12α-monooxygenase; sterol 12α-hydroxylase (ambiguous); CYP8B1; cytochrome P450 8B1. Enzyme Commission Number: EC 1.14.13.96. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0904; 5β-cholestane-3α,7α-diol 12α-hydroxylase; EC 1.14.13.96; 5β-cholestane-3α,7α-diol 12α-monooxygenase; sterol 12α-hydroxylase (ambiguous); CYP8B1; cytochrome P450 8B1. Cat No: EXWM-0904.
7α-hydroxycholest-4-en-3-one 12α-hydroxylase
A P-450 heme-thiolate protein. Requires EC 1.6.2.4, NADPH-hemoprotein reductase and cytochrome b5 for maximal activity. This enzyme is important in bile acid biosynthesis, being responsible for the balance between the formation of cholicacid and chenodeoxycholicacid. Group: Enzymes. Synonyms: 7α-hydroxy-4-cholesten-3-one 12α-monooxygenase; CYP12; sterol 12α-hydroxylase (ambiguous); HCO 12α-hydroxylase. Enzyme Commission Number: EC 1.14.18.8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0970; 7α-hydroxycholest-4-en-3-one 12α-hydroxylase; EC 1.14.18.8; 7α-hydroxy-4-cholesten-3-one 12α-monooxygenase; CYP12; sterol 12α-hydroxylase (ambiguous); HCO 12α-hydroxylase. Cat No: EXWM-0970.
7α-Hydroxy Cholesterol
7α-hydroxy Cholesterol is an oxysterol and a precursor in the biosynthesis of the bile acids cholicacid and chenodeoxycholicacid. 7α-Hydroxy Cholesterol is also a secondary metabolite of Cholesterol. 7α-hydroxy Cholesterol (40 μM) increases levels of the adhesion molecules ICAM-1, VCAM-1, and E-selectin in human umbilical vein endothelial cells (HUVECs). Synonyms: cholest-5-ene-3β,7α-diol; 7alpha-hydroxy-cholesterol; 7-alpha-OHC. Grades: > 95%. CAS No. 566-26-7. Molecular formula: C27H46O2. Mole weight: 402.65.
CAP 3
CAP 3 is a cholicacid-peptide conjugate (CAP) with antibacterial activity. It is active against the Gram-negative bacteria E. coli, K. pneumoniae, and A. baumanii (MIC99s = 8, 16, and 16 μM, respectively). CAP 3 increases the fluidity of model Gram-negative bacterial membranes and binds to LPS in vitro. It reduces the biomass and number of colony-forming units in E. coli biofilms in a concentration-dependent manner. CAP 3 inhibits E. coli biofilm formation on catheters implanted in mice infected with E. coli at the incision site when applied as a coating on the catheters. CAP 3 (40 mg/kg) also reduces bacterial load in E. coli-infected wounds in mice. It is cytotoxic to A459 cells (IC50 = 56.4 μM) and has hemolytic activity against human red blood cells with a 50% lysis (HC50) value of 48 μM. Synonyms: CAP 3; CHEMBL5173640; benzyl (4R)-4-[(3R, 5S, 7R, 8R, 9S, 10S, 12S, 13R, 14S, 17R)-3, 7, 12-tris[[2-[(2-amino-3-methylbutanoyl)amino]acetyl]oxy]-10, 13-dimethyl-2, 3, 4, 5, 6, 7, 8, 9, 11, 12, 14, 15, 16, 17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate. Grades: ≥98%. Molecular formula: C52H82N6O11. Mole weight: 967.3.
CHAPS
CHAPS, a derivative of Cholicacid, is a zwitterionic detergent for solubilizing membrane proteins. CHAPS is used for stabilization of various protein-DNA complexes and can retain biochemical activity of proteins in solution [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 75621-03-3. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-15435.
Non-denaturing zwitterionic detergent with cholicacid and sulfobetaine moieties, used to dissolve biological membranes, useful for protein extraction methods due to its ease of removal by dialysis or gel filtration. Low background UV absorption for protein detection.Designed by Good, et al., and typically referred to as Goods buffer useful in cell culture media formulations. Selection of biological buffer systems should include the following criteria: exclusion by biological membranes, low absorption between 240 and 700nm, chemically stable, and stable to temperature and concentration changes. Group: Biochemicals. Alternative Names: (3-[ (3-Cholamidopropyl) dimethylammonio]-1-propanesulfonate) ; N,N-Dimethyl-N-(3-sulfopropyl)-3-[[(3α,5 β, 7α, 12α)-3, 7, 12-trihydroxy-24-oxocholan-24-yl]amino]-1-propanaminium Inner Salt; CHAPS. Grades: Molecular Biology Grade. CAS No. 75621-03-3. Pack Sizes: 5g, 25g, 100g. Molecular Formula: C32H58N2O7S, Molecular Weight: 614.88. US Biological Life Sciences.
Worldwide
CHAPS hydrate
CHAPS hydrate, a derivative of Cholicacid, is a zwitterionic detergent for solubilizing membrane proteins. CHAPS hydrate is used for stabilization of various protein-DNA complexes and can retain biochemical activity of proteins in solution [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 331717-45-4. Pack Sizes: 500 mg; 1 g. Product ID: HY-15435A.
CHAPSO
Non-denaturing zwitterionic detergent with cholicacid and sulfobetaine moieties, used to dissolve biological membranes, useful for protein extraction methods due to its ease of removal by dialysis or gel filtration. Low background UV absorption for protein detection. Group: Biochemicals. Alternative Names: (3-[ (3-Cholamidopropyl) dimethylammonio]-2-hydroxy-1-propanesulfonate) . Grades: Molecular Biology Grade. CAS No. 82473-24-3. Pack Sizes: 5g, 25g. US Biological Life Sciences.
Requires Mg2+ for activity. The mammalian enzyme is membrane-bound and catalyses the first step in the conjugation of bile acids with amino acids, converting bile acids into their acyl-CoA thioesters. Chenodeoxycholate, deoxycholate, lithocholate and trihydroxycoprostanoate can also act as substrates. The bacterial enzyme is soluble and participates in an anaerobic bile acid 7 α-dehydroxylation pathway. Group: Enzymes. Synonyms: BAL; bile acid CoA ligase; bile acid co. Enzyme Commission Number: EC 6.2.1.7. CAS No. 9027-90-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5709; cholate-CoA ligase; EC 6.2.1.7; 9027-90-1; BAL; bile acid CoA ligase; bile acid coenzyme A ligase; choloyl-CoA synthetase; choloyl coenzyme A synthetase; cholic thiokinase; cholate thiokinase; cholicacid:CoA ligase; 3α,7α,12α-trihydroxy-5β-cholestanoyl coenzyme A synthetase; 3α,7α,12α-trihydroxy-5β-cholestanoate-CoA ligase; 3α,7α,12α-trihydroxy-5β-cholestanoate-CoA synthetase; THCA-CoA ligase; 3α,7α,12α-trihydroxy-5β-cholestanate-CoA ligase; 3α,7α,12α-trihydroxy-5β-cholestanate:CoA ligase (AMP-forming); cholyl-CoA synthetase; trihydroxycoprostanoyl-CoA synthetase. Cat No: EXWM-5709.
Ethyl Deoxycholate
Ethyl Deoxycholate is the ethyl ester of the common bile salt DeoxycholicAcid (D232645), a CholicAcid (C432600) derivative used as a component in cell lysis buffers. Group: Biochemicals. Grades: Highly Purified. CAS No. 69519-35-3. Pack Sizes: 100mg, 250mg. Molecular Formula: C26H44O4, Molecular Weight: 420.63. US Biological Life Sciences.
Worldwide
Methyl cholate
Methyl Cholate is methyl ester form of Cholicacid. Cholicacid is one of the major bile acids produced by the liver, where it is synthesized from cholesterol [1]. Uses: Scientific research. Group: Natural products. CAS No. 1448-36-8. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-107830.
Methyl cholatesee
Methyl cholatesee. Group: Biochemicals. Alternative Names: (3a,5b,7a,12a)-3,7,12-Trihydroxycholan-24-oic acid methyl ester; CholicAcid ?ethyl ?ster; Methyl 3a,7a,12a-trihydroxy-5b-cholan-24-oate. Grades: Highly Purified. CAS No. 1448-36-8. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C25H42O5. US Biological Life Sciences.
Worldwide
Methyl Isolithocholate-d7
Methyl Isolithocholate-d7 is a labelled cholicacid derivative as TGR5 modulator. Found in ox bile, human bile, rabbit bile, and in ox and pig gallstones. Group: Biochemicals. Alternative Names: Methyl 3 β-Hydroxy-5 β-cholanoate; 3 β-Hydroxy-5 β-cholanic Acid Methyl Ester-d7; (3 β,5 β)-3-Hydroxycholan-24-oic Acid Methyl Ester-d7. Grades: Highly Purified. CAS No. 5405-42-5. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
Methyl Lithocholate
Methyl Lithocholate is an derivative of LithocholicAcid (L469180),a cholicacid derivative as TGR5 modulator. Found in ox bile, human bile, rabbit bile, and in ox and pig gallstones. Group: Biochemicals. Alternative Names: LithocholicAcid Methyl Ester-d7; Methyl 3α-Hydroxy-5 β-cholan-24-oate-d7; Methyl 3α-Hydroxy-5 β-cholanoate-d7; 3α-Hydroxy-5 β-cholanic Acid-d7; 3α-Hydroxy-5 β-cholan-24-oic Acid Methyl Ester-d7; (3α,5 β)-3-Hydroxycholan-24-oic Acid Methyl Ester-d7. Grades: Highly Purified. CAS No. 1249-75-8. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Methyl Lithocholate-d7
Isotope labelled derivative of LithocholicAcid (L469180),a cholicacid derivative as TGR5 modulator. Found in ox bile, human bile, rabbit bile, and in ox and pig gallstones. Group: Biochemicals. Alternative Names: LithocholicAcid Methyl Ester-d7; Methyl 3α-Hydroxy-5 β-cholan-24-oate-d7; Methyl 3α-Hydroxy-5 β-cholanoate-d7; 3α-Hydroxy-5 β-cholanic Acid-d7; 3α-Hydroxy-5 β-cholan-24-oic Acid Methyl Ester-d7; (3α,5 β)-3-Hydroxycholan-24-oic Acid Methyl Ester-d7. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Ox bile extract powder
Bile Extract Powder (Ox Bile Desiccated), dried or desiccated which contains ox bile acids. This powder is specifically been developed for Pharmaceutical Industry, which is prepared by a low temperature dehydration process which ensures a uniform product. Bile Extract Powder, dried is a mixture of conjugated bile acids (CholicAcid, DeoxycholicAcid, Taurocholic and GlycocholicAcids). It is a straight forward drying of Ox Bile liquid, which contains all of the constituents characteristics, found in Ox Bile. None of the bile salts, bile pigments cholesterol, mucin, etc. has been removed. Applications: Bile extract powder is used to emulsify lipids in food passing through the intestine to enable fat digestion and absorption through the intestinal wall. bile salts aid in the breakdown of saturated fats that the digestive system has not been able to convert into unsaturated fats. the body uses these unsaturated fats to manufacture essential vitamins and hormones. many individuals without proper gallbladder function find it helpful to supplement with the best bile salts. Group: Others. Synonyms: Ox bile extract; Ox bile; BILE SALT; Ox . Ox bile extract powder. Activity: Cholicacid 40%-55%. Appearance: Greenish to yellowish colour free flowing powder. Source: Ox bile. Ox bile extract powder; Ox bile extract; Ox bile; BILE SALT; Ox bile powder. Cat No: OBE-001.
taurochenodeoxycholate 6α-hydroxylase
A heme-thiolate protein (P-450). Requires cytochrome b5 for maximal activity. Acts on taurochenodeoxycholate, taurodeoxycholate and less readily on lithocholate and chenodeoxycholate. In adult pig (Sus scrofa), hyocholicacid replaces cholicacid as a primary bile acid. Group: Enzymes. Synonyms: CYP3A4; CYP4A21; taurochenodeoxycholate 6α-monooxygenase. Enzyme Commission Number: EC 1.14.13.97. CAS No. 105669-85-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0905; taurochenodeoxycholate 6α-hydroxylase; EC 1.14.13.97; 105669-85-0; CYP3A4; CYP4A21; taurochenodeoxycholate 6α-monooxygenase. Cat No: EXWM-0905.
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