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100g Pack Size. Group: Bioactive Small Molecules, Biochemicals, Organics. Formula: C24H40O5. CAS No. 81-25-4. Prepack ID 25751419-100g. Molecular Weight 408.57. See USA prepack pricing.
Cholic acid
Cholic acid could inhibit the activity of cardiac myocytes by causing calcium overload, thereby leading to the sudden fetal death in ICP. Uses: Hypotensive. Synonyms: Colalin; Cholalic acid; cholate; Cholalin; Cholsaeure; 5β-cholanic acid-3α,7α,12α-triol. Grades: >98%. CAS No. 81-25-4. Molecular formula: C24H40O5. Mole weight: 408.58.
Cholic acid
Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholic acid is orally active [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 81-25-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 1 g. Product ID: HY-N0324.
Cholic acid
Cholic acid. Synonyms: Cholalic Acid. CAS No. 81-25-4. Product ID: PE-0435. Molecular formula: C24H40O5. Mole weight: 408.32. Category: Dispersants. Product Keywords: Pharmaceutical Excipients; Excipients for Liquid Dosage Form; Cholic acid; Dispersion Excipients; Dispersants; C24H40O5; 81-25-4; 81-25-4. UNII: NA. Grade: Pharmceutical Excipients. Stability and Storage Conditions: Keep sealed and away from light in a cool and dry place. Source and Preparation: All kinds of cholic acids can be combined with glycine or taurine with peptide bonds to form various bile acids. The bile of pig, cow and sheep was hydrolyzed with cholecylanin and alkali, and the pH was adjusted to 3.0 with hydrochloric acid. The precipitates were extracted and washed to neutral, refined with ethanol and activated carbon, washed with glacial acetic acid, and recrystallized. There are several kinds of cholic acids due to the different number and location of hydroxyl groups. The main ones are 3, 7, 12-trihydroxycholic acid and deoxycholic acid (i.e. 3, 12-dihydroxycholic acid). Safety: This product is non-toxic, ADI 0-1.25MG/kg.
Cholic acid
Cholic acid. Synonyms: Cholalic Acid. CAS No. 81-25-4. Product ID: PE-0570. Molecular formula: C24H40O5. Mole weight: 408.32. Category: Polymer Solid Dispersant; Emulsifier. Product Keywords: Excipients for Liquid Dosage Form; Emulsifier Excipients; PE-0570; Cholic acid; Polymer Solid Dispersant; Emulsifier; C24H40O5; 81-25-4. UNII: NA. Grade: Pharmceutical Excipients. Stability and Storage Conditions: Keep sealed and away from light in a cool and dry place. Source and Preparation: All kinds of cholic acids can be combined with glycine or taurine with peptide bonds to form various bile acids. The bile of pig, cow and sheep was hydrolyzed with cholecylanin and alkali, and the pH was adjusted to 3.0 with hydrochloric acid. The precipitates were extracted and washed to neutral, refined with ethanol and activated carbon, washed with glacial acetic acid, and recrystallized. There are several kinds of cholic acids due to the different number and location of hydroxyl groups. The main ones are 3, 7, 12-trihydroxycholic acid and deoxycholic acid (i.e. 3, 12-dihydroxycholic acid). Safety: This product is non-toxic, ADI 0~1.25MG/kg.
Choleretic produced by and isolated from liver cells. Group: Biochemicals. Alternative Names: (3α,5 β, 7α12α)-3, 7, 12-Trihydroxy-cholan-24-oic Acid; 17 β-(1-Methyl-3-carboxy-propyl)etiocholane-3α, 7α, 12α-triol;5 β-Cholic Acid; Cholalic Acid; Cholalin; Colalin; NSC-6135. Grades: Highly Purified. CAS No. 81-25-4. Pack Sizes: 25g, 50g, 100g, 250g, 500g, 1Kg. Molecular Formula: C24H40O5, Molecular Weight: 408.57. US Biological Life Sciences.
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Cholic Acid
Cholic Acid - Product ID: NST-10-206. Category: sterols. Alternative Names: Cholalic acid, Cholalin, Cholbam, Colalin, Kolbam, Orphacol. Purity: 98%. Test method: HPLC. CAS No. 81-25-4. Pack Sizes: 25g, 50g, 125g, 250g. Appearance: White Powder. Molecular formula: C24H40O5. Mole weight: 408.57. Storage: +2 +8 °C.
Cholic acid-24-13C
Cholic acid-24-13C. Group: Biochemicals. Grades: Highly Purified. CAS No. 52886-36-9. Pack Sizes: 100mg, 250mg, 500mg. Molecular Formula: C24H40O5. US Biological Life Sciences.
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Cholic acid 7-sulfate
Cholic acid 7-sulfate (7-Sulfocholic acid), a metabolite of Cholic acid, is a Takeda G-protein receptor 5 (TGR5) agonist. Cholic acid 7-sulfate can increase Tgr5 expression and induce GLP-1 secretion [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 7-Sulfocholic acid. CAS No. 60320-05-0. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-126855.
Cholic acid-d4
Cholic acid-d 4 is the deuterium labeled Cholic acid. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 116380-66-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0324S.
Cholic Acid-d4
Cholic Acid-d4 is a labelled analog of Cholic acid (C432600) which is a choleretic produced by, and isolated from liver cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 116380-66-6. Pack Sizes: 1mg, 5mg. Molecular Formula: C24H36D4O5. US Biological Life Sciences.
Cholic acid sodium is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholic acid sodium is orally active [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Sodium cholate. CAS No. 361-09-1. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-N0324A.
Cholic acid sodium salt
100g Pack Size. Group: Biochemicals, Diagnostic Raw Materials. Formula: C24H39NaO5. CAS No. 361-09-1. Prepack ID 15562390-100g. Molecular Weight 430.55. See USA prepack pricing.
Cholic acid sodium salt
Cholic acid sodium salt. Group: Biochemicals. Grades: Highly Purified. CAS No. 361-09-1. Pack Sizes: 10g, 25g, 50g, 100g, 250g. Molecular Formula: C24H39NaO5. US Biological Life Sciences.
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Cholic acid sodium salt hydrate
100g Pack Size. Group: Biochemicals, Detergents, Research Organics & Inorganics. Formula: C24H39NaO5 · xH2O. CAS No. 73163-53-8. Prepack ID 13237653-100g. Molecular Weight 448.57. See USA prepack pricing.
12-Hydroxy Taurolithocholic Acid-2,2,3,4,4-d5 O-3-Glucuronide Dipotassium Salt
12-Hydroxy Taurolithocholic Acid-2,2,3,4,4-d5 O-3-Glucuronide Dipotassium Salt is a labelled analogue of 12-Hydroxy Taurolithocholic Acid O-3-Glucuronide Dipotassium Salt (H954095), an impurity of Cholic Acid (C432600), which is a choleretic produced by and isolated from liver cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C32H46D5NO12S.2K, Molecular Weight: 757.04. US Biological Life Sciences.
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12-Hydroxy Taurolithocholic Acid-2,2,3,4,4-d5 Sulfate Disodium Salt
12-Hydroxy Taurolithocholic Acid-2,2,3,4,4-d5 Sulfate Disodium Salt is a laballed analogue of 2-Hydroxy Taurolithocholic Acid Sulfate Disodium Salt (H954090), an impurity of Cholic Acid (C432600), which is a choleretic produced by and isolated from liver cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C26H38D5NNa2O9S2, Molecular Weight: 628.76. US Biological Life Sciences.
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12-Hydroxy Taurolithocholic Acid O-3-Glucuronide Dipotassium Salt
12-Hydroxy Taurolithocholic Acid O-3-Glucuronide Dipotassium Salt is an impurity of Cholic Acid, a choleretic produced by and isolated from liver cells. Synonyms: (3α,5β,12α)-12-Hydroxy-24-oxo-24-[(2-sulfoethyl)amino]cholan-3-yl β-D-Glucopyranosiduronic Acid Dipotassium Salt; Cholane β-D-Glucopyranosiduronic Acid Derivative. CAS No. 75672-37-6. Molecular formula: C32H51NO12S 2K. Mole weight: 752.01.
12-Hydroxy Taurolithocholic Acid O-3-Glucuronide Dipotassium Salt
12-Hydroxy Taurolithocholic Acid O-3-Glucuronide Dipotassium Salt is an impurity of Cholic Acid (C432600), a choleretic produced by and isolated from liver cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 75672-37-6. Pack Sizes: 1mg, 2mg. Molecular Formula: C32H51NO12S.2K, Molecular Weight: 752.01. US Biological Life Sciences.
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12-Hydroxy Taurolithocholic Acid Sulfate Disodium Salt
2-Hydroxy Taurolithocholic Acid Sulfate Disodium Salt is an impurity of Cholic Acid (C432600), a choleretic produced by and isolated from liver cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 66874-07-5. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C26H43NNa2O9S2. US Biological Life Sciences.
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3-?Oxocholic acid
3-Oxocholic acid is an oxo-bile acid metabolite and also a major degradation product from cholic by C. perfringens in the intestine. 3-Oxocholic acid is steroid acid found predominantly in bile of mammals [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: 3-Dehydrocholic acid. CAS No. 2304-89-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-N7387.
Allocholic acid
Allocholic acid. Group: Biochemicals. Alternative Names: 3-a,7-a,12-a-Trihydroxy-5-a-cholanoic acid; 5a-Cholic acid. Grades: Highly Purified. CAS No. 2464-18-8. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C24H40O5. US Biological Life Sciences.
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Allocholic acid
Allocholic acid is a bile acid metabolized from animals. Allocholic acid is also a precursor to petromyzonol. Synonyms: 3alpha,7alpha,12alpha-Trihydroxy-5alpha-cholan-24-oic acid; 5alpha-cholic acid; 5α-cholanic acid-3α,7α,12α-triol. Grades: >99%. CAS No. 2464-18-8. Molecular formula: C24H40O5. Mole weight: 408.57.
Allocholic acid
Allocholic acid is a typically fetal bile acid found in vertebrates and reappears during liver regeneration and carcinogenesis, besides it is also a conjugate acid of allocholate and an isomer of cholic acid. Allocholic acid is a potent and specific stimulant of the adult olfactory system, it has a role as a marine metabolite, a rat metabolite and a human metabolite [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 2464-18-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-125934.
Apocholic acid
Apocholic Acid is originally produced from Cholic Acid which is a choleretic produced by and isolated from liver cells. Synonyms: 3alpha,12alpha-Dihydroxy-5beta-chol-8(14)-en-24-oic acid; 5β,8(14)-Cholen-24-oic acid-3α,12α-diol; 3α,12α-Dihydroxy-5β,8(14)-cholen-24-oic acid. Grades: >99%. CAS No. 641-81-6. Molecular formula: C24H38O4. Mole weight: 390.56.
Dehydrocholic Acid
Dehydrocholic Acid is a derivative of Cholic Acid and manufactured by the oxidation of cholic acid. It is produced by choleretic and isolated from liver cells. It acts as a hydrocholeretic, increasing bile output to clear increased bile acid load. Uses: Dehydrocholic acts as a hydrocholeretic, increasing bile output to clear increased bile acid load. Synonyms: Decholin; Dehystolin; Oxycholin; Ketocholanic acid; Felacrinos; Sanocholen; 3,7,12-Trioxocholanic acid. Grades: >98%. CAS No. 81-23-2. Molecular formula: C24H34O5. Mole weight: 402.52.
Deoxycholic Acid-2,2,3,4,4-d5 3-O- β-D-Glucuronide Disodium Salt
Deoxycholic Acid-2,2,3,4,4-d5 3-O- β-D-Glucuronide Disodium Salt is a labelled analogue of Deoxycholic Acid 3-O- β-D-Glucuronide Disodium Salt (D232720), an impurity of Cholic Acid (C432600), which is a choleretic produced by and isolated from liver cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 2mg. Molecular Formula: C30H41D5Na2O10, Molecular Weight: 617.69. US Biological Life Sciences.
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Deoxycholic Acid 3-O- β-D-Glucuronide Disodium Salt
Deoxycholic Acid 3-O- β-D-Glucuronide Disodium Salt is an impurity of Cholic Acid (C432600), a choleretic produced by and isolated from liver cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 59274-67-8. Pack Sizes: 1mg, 2mg. Molecular Formula: C30H46Na2O10, Molecular Weight: 612.66. US Biological Life Sciences.
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Deoxycholic Acid 3-O-β-D-Glucuronide Disodium Salt
Deoxycholic Acid 3-O-β-D-Glucuronide Disodium Salt is an impurity of Cholic Acid, a choleretic produced by and isolated from liver cells. Synonyms: (3α,5β,12α)-23-Carboxy-12-hydroxy-24-norcholan-3-yl-β-D-glucopyranosiduronic Acid Disodium Salt. Grades: 98%. CAS No. 59274-67-8. Molecular formula: C30H46Na2O10. Mole weight: 612.66.
Deoxycholic Acid-d5 3-O-Sulfate Disodium Salt
Deoxycholic Acid-d5 3-O-Sulfate Disodium Salt is a labelled impurity of Cholic Acid (C432600), it is produced and isolated from liver cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C24H33D5Na2O7S, Molecular Weight: 521.63. US Biological Life Sciences.
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Glycocholic Acid-d5
The product of conjugation of cholic acid with glycine; chief ingredient of the bile of herbivorous animals. In the weakly alkaline bile fluid glycocholic acid exists as the sodium salt. Group: Biochemicals. Alternative Names: N-[(3α,5 β, 7α, 12α)-3, 7, 12-?rihydroxy-24-oxocholan-24-yl]glycine-d5; N-Choloylglycine. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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Glycocholic Acid Hydrate
Labeled Glycocholic Acid. The product of conjugation of cholic acid with glycine; chief ingredient of the bile of herbivorous animals. In the weakly alkaline bile fluid glycocholic acid exists as the sodium salt. Group: Biochemicals. Alternative Names: N-[(3α,5 β, 7α, 12α)-3, 7, 12-?rihydroxy-24-oxocholan-24-yl]glycine Hydrate; N-Choloylglycine. Grades: Highly Purified. CAS No. 475-31-0. Pack Sizes: 1g. US Biological Life Sciences.
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Icomidocholic acid
Icomidocholic acid (Aramchol) is a lipid molecule synthesized from cholic acid and arachidic acid. Icomidocholic acid is an orally active SCD1 inhibitor and cholesterol solubilizer with antifibrotic effects. Icomidocholic acid can reduce liver fat content, dissolve cholesterol crystals and prevent gallstone formation. Icomidocholic acid can be used in the study of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Aramchol; C20-FABAC. CAS No. 246529-22-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19796.
Lithocholic Acid
A cholic acid derivative as TGR5 modulator. Found in ox bile, human bile, rabbit bile, and in ox and pig gallstones. Group: Biochemicals. Alternative Names: (3α,5 β)-3-Hydroxycholan-24-oic Acid; 17 β - (1-Methyl-3-carboxypropyl) etiocholan-3α -ol; 3-Hydroxycholan-24-oic Acid; 3α-Hydroxy-5 β-cholan-24-oate; 3α-Hydroxy-5 β-cholan-24-oic Acid; 3α-Hydroxy-5 β-cholanic Acid; 3α-Hydroxy-5 β-cholanoic Acid; 3α-Hydroxycholanic Acid; NSC 683770. Grades: Highly Purified. CAS No. 434-13-9. Pack Sizes: 1g. US Biological Life Sciences.
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Lithocholic Acid
A cholic acid derivative as TGR5 modulator. Found in ox bile, human bile, rabbit bile, and in ox and pig gallstones. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3α-Hydroxy-5β-cholanic acid. Product Category: Steroidal Compounds. Appearance: White to off-white powder. CAS No. 434-13-9. Molecular formula: C24H40O3. Mole weight: 376.57. Purity: 0.98. IUPACName: (4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-Hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid. Canonical SMILES: CC(CCC(=O)O)C1CCC2C1(CCC3C2CCC4C3(CCC(C4)O)C)C. Density: 1.0454 g/cm³. ECNumber: 207-099-1. Product ID: ACM434139. Alfa Chemistry ISO 9001:2015 Certified.
Lithocholic Acid 24-Ac-O-β-D-Glucuronide
Lithocholic Acid 24-Ac-O-β-D-Glucuronide is an impurity of Lithocholic Acid (L469180), a cholic acid derivative as TGR5 modulator. Found in ox bile, human bile, rabbit bile, and in ox and pig gallstones. Synonyms: 1-[(3α,5β)-3-Hydroxycholan-24-oate] β-D-Glucopyranuronic Acid. CAS No. 142780-61-8. Molecular formula: C30H48O9. Mole weight: 552.7.
Lithocholic Acid 3-O-Glucuronide
Lithocholic Acid 3-O-Glucuronide is an impurity of Lithocholic Acid, a cholic acid derivative as TGR5 modulator. Found in ox bile, human bile, rabbit bile, and in ox and pig gallstones. Synonyms: (3α,5β)-23-Carboxy-24-norcholan-3-yl β-D-Glucopyranosiduronic Acid; Lithocholic Acid 3-Glucuronide. Grades: 98%. CAS No. 75239-91-7. Molecular formula: C30H48O9. Mole weight: 552.7.
Lithocholic Acid-d4
A labeled cholic acid derivative as TGR5 modulator. Found in ox bile, human bile, rabbit bile, and in ox and pig gallstones. Group: Biochemicals. Alternative Names: (3α,5 β)-3-Hydroxycholan-24-oic Acid-d4; 17 β - (1-Methyl-3-carboxypropyl) etiocholan-3α -ol-d4; 3-Hydroxycholan-24-oic Acid-d4; 3α-Hydroxy-5 β-cholan-24-oate-d4; 3α-Hydroxy-5 β-cholan-24-oic Acid-d4; 3α-Hydroxy-5 β-cholanic Acid-d4; 3α-Hydroxy-5 β-cholanoic Acid-d4; 3α-Hydroxycholanic Acid-d4; NSC 683770-d4. Grades: Highly Purified. CAS No. 83701-16-0. Pack Sizes: 1mg. US Biological Life Sciences.
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Lithocholic Acid-d5
A labelled cholic acid derivative as TGR5 modulator. Found in ox bile, human bile, rabbit bile, and in ox and pig gallstones. Group: Biochemicals. Alternative Names: (3α,5 β)-3-Hydroxycholan-24-oic Acid-d5; 17 β - (1-Methyl-3-carboxypropyl) etiocholan-3α -ol-d5; 3-Hydroxycholan-24-oic Acid-d5; 3α-Hydroxy-5 β-cholan-24-oate-d5; 3α-Hydroxy-5 β-cholan-24-oic Acid-d5; 3α-Hydroxy-5 β-cholanic Acid-d5; 3α-Hydroxy-5 β-cholanoic Acid-d5; 3α-Hydroxycholanic Acid-d5; NSC 683770-d5. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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Nor Cholic Acid
A novel bile acid, an analogue of Cholic acid. Group: Biochemicals. Alternative Names: (3α,5 β, 7α, 12α)-3, 7, 12-Trihydroxy-24-norcholan-23-oic Acid; 3α, 7α, 12α-Trihydroxy- 23-nor-5 β-cholanic Acid; 23-Norcholic Acid; 24-Norcholic Acid; 3α, 7α, 12α-Trihydroxy-24-nor-5 β-cholan-23-oic Acid; Norcholic Acid. Grades: Highly Purified. CAS No. 60696-62-0. Pack Sizes: 100mg. US Biological Life Sciences.
Sulfolithocholic Acid is an derivative of Lithocholic Acid (L469180), a cholic acid derivative and TGR5 modulator found in ox bile, human bile, rabbit bile, and in ox and pig gallstones. Group: Biochemicals. Alternative Names: 3α-Sulfate-5 β-cholan-24-oic Acid Trimethylamine Salt; Lithocholic Acid 3-O-Sulfate Trimethylamine Salt ; Lithocholic Acid 3α-Sulfate Trimethylamine Salt; (3α,5 β)-3-(Sulfooxy)-cholan-24-oic Acid Trimethylamine Salt. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Choleretic; Its sodium salt is a bile salt formed in the liver by conjugation of cholic acid with taurine that is involved in the emulsification of lipids used to solubilize lipids and membrane-bound proteins. Uses: Used to solubilize lipids and membrane-bound proteins. Synonyms: 2-[[(3α, 5β, 7α, 12α)-3, 7, 12-trihydroxy-24-oxocholan-24-yl]amino]-ethanesulfonic acid, monosodium salt. Grades: ≥98%. CAS No. 345909-26-4. Molecular formula: C26H46NNaO8S. Mole weight: 555.70.
(3α,5R,6 β,20S)-6-Methoxy-3,5-cyclopregnane-30-methanol 4-Methylbenzenesulfonate is a tosylated derivative that have been utilized in the biosynthetic studies of cholic acids and vitamin D3 derivatives. Group: Biochemicals. Alternative Names: (20S)-6 β -Methoxy-20- (p-toluenesulfonyloxy methyl ) -3 α , 5-cyclo-5 α -pregnane; (3α,5R,6 β,20S)-6-Methoxy-3,5-cyclopregnane-20-methanol 20- (4-Methyl Benzene sulfonate) . Grades: Highly Purified. CAS No. 51231-24-4. Pack Sizes: 2.5mg. US Biological Life Sciences.
This enzyme forms part of the rat peroxisomal multifunctional enzyme perMFE-2, which also exhibits a dehydrogenase activity. The enzyme is involved in the β-oxidation of the cholesterol side chain in the cholic-acid-biosynthesis pathway. Group: Enzymes. Synonyms: 46 kDa hydratase 2; (24R,25R)-3α,7α,12α,24-tetrahydroxy-5β-cholestanoyl-CoA hydro-lyase. Enzyme Commission Number: EC 4.2.1.107. CAS No. 152787-68-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4946; 3α,7α,12α-trihydroxy-5β-cholest-24-enoyl-CoA hydratase; EC 4.2.1.107; 152787-68-3; 46 kDa hydratase 2; (24R,25R)-3α,7α,12α,24-tetrahydroxy-5β-cholestanoyl-CoA hydro-lyase. Cat No: EXWM-4946.
(3 β,5α,6 β,20S)-6-Methoxy-3,5-cyclopregnane-20-methanol is a functionalized steroid used as a tool in the biosynthetic studies of cholic acids and vitamin D3 derivatives. Group: Biochemicals. Alternative Names: (3α,5R,6 β,20S)-6-Methoxy-3,5-cyclopregnane-20-methanol. Grades: Highly Purified. CAS No. 51231-23-3. Pack Sizes: 2.5mg. US Biological Life Sciences.
(3 β,5 β, 7α, 12α)-3-(Formyloxy)-7, 12-dihydroxycholan-24-oic Acid Methyl Ester is an intermediate in the synthesis 3 β-Cholic Acid (C432605), a possible progesterone (P755900) metabolite. Group: Biochemicals. Alternative Names: Methyl 3 β-(Formyloxy)-7α,12α-dihydroxycholanate. Grades: Highly Purified. CAS No. 42921-40-4. Pack Sizes: 250mg. US Biological Life Sciences.
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5β-Cholanic acid-3,12-dione
5β-Cholanic acid-3,12-dione. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3,12-Dioxo-5beta-cholanoic acid; 3,12-dioxo-7-deoxycholic acid; EINECS 220-982-6; Cholic acid,dehydrodeoxy; Dehydrodeoxycholic acid; 3,12-dioxo-cholanic acid; 3,12-dioxocholanoic acid; 3,12-Diketo-5beta-cholanic acid. Product Category: Steroidal Compounds. CAS No. 2958-5-6. Molecular formula: C24H36O4. Mole weight: 388.54. Purity: 0.95. IUPACName: (4R)-4-[(5R,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-3,12-dioxo-2,4,5,6,7,8,9,11,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoicacid. Canonical SMILES: CC(CCC(=O)O)C1CCC2C1(C(=O)CC3C2CCC4C3(CCC(=O)C4)C)C. Density: 1.12g/cm³. ECNumber: 220-982-6. Product ID: ACM2958056. Alfa Chemistry ISO 9001:2015 Certified.
5β-Cholanic acid-3α,7α,12α-triol
5β-Cholanic acid-3α,7α,12α-triol. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CHOLATE; Cholic acd; CHOLALIC ACID; AHR 3053-13C3; Cholic&Cyclosphorine; CHOLALIN; Cholic acid. Product Category: Steroidal Compounds. Appearance: white to off-white crystalline powder. CAS No. 81-25-4. Molecular formula: C24H40O5. Mole weight: 408.57. Purity: 0.98. IUPACName: (4R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoicacid. Canonical SMILES: CC(CCC(=O)O)C1CCC2C1(C(CC3C2C(CC4C3(CCC(C4)O)C)O)O)C. Density: 1.184g/cm³. ECNumber: 201-337-8. Product ID: ACM81254. Alfa Chemistry ISO 9001:2015 Certified.
5β-Cholanic acid-3α,7α,12α-triol methyl ester
5β-Cholanic acid-3α,7α,12α-triol methyl ester. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CHOLIC ACID METHYL ESTER; Methyl Cholate; Cholic acid methyl ester. Product Category: Steroidal Compounds. Appearance: Off-White Solid. CAS No. 1448-36-8. Molecular formula: C25H42O5. Mole weight: 422.61. Purity: 0.98. IUPACName: methyl(4R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate. Canonical SMILES: CC(CCC(=O)OC)C1CCC2C1(C(CC3C2C(CC4C3(CCC(C4)O)C)O)O)C. Density: 1.141g/cm³. ECNumber: 215-903-7. Product ID: ACM1448368. Alfa Chemistry ISO 9001:2015 Certified.
5β-CHOLANIC ACID-3α, 7α, 12α-TRIOL SODIUM SALT
5β-CHOLANIC ACID-3α, 7α, 12α-TRIOL SODIUM SALT. Group: Biochemicals. Alternative Names: CHOLIC ACID SODIUM SALTSODIUM CHOLATE. CAS No. 73163-53-8. US Biological Life Sciences.
Worldwide
5β-cholestane-3α,7α-diol 12α-hydroxylase
A heme-thiolate protein (P-450). This is the key enzyme in the biosynthesis of the bile acid cholic acid (3α,7α,12α-trihydroxy-5β-cholanoic acid). The activity of this enzyme determines the biosynthetic ratio between cholic acid and chenodeoxycholic acid. The enzyme can also hydroxylate the substrate at the 25 and 26 position, but to a lesser extent. Group: Enzymes. Synonyms: 5β-cholestane-3α,7α-diol 12α-monooxygenase; sterol 12α-hydroxylase (ambiguous); CYP8B1; cytochrome P450 8B1. Enzyme Commission Number: EC 1.14.13.96. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0904; 5β-cholestane-3α,7α-diol 12α-hydroxylase; EC 1.14.13.96; 5β-cholestane-3α,7α-diol 12α-monooxygenase; sterol 12α-hydroxylase (ambiguous); CYP8B1; cytochrome P450 8B1. Cat No: EXWM-0904.
7α-hydroxycholest-4-en-3-one 12α-hydroxylase
A P-450 heme-thiolate protein. Requires EC 1.6.2.4, NADPH-hemoprotein reductase and cytochrome b5 for maximal activity. This enzyme is important in bile acid biosynthesis, being responsible for the balance between the formation of cholic acid and chenodeoxycholic acid. Group: Enzymes. Synonyms: 7α-hydroxy-4-cholesten-3-one 12α-monooxygenase; CYP12; sterol 12α-hydroxylase (ambiguous); HCO 12α-hydroxylase. Enzyme Commission Number: EC 1.14.18.8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0970; 7α-hydroxycholest-4-en-3-one 12α-hydroxylase; EC 1.14.18.8; 7α-hydroxy-4-cholesten-3-one 12α-monooxygenase; CYP12; sterol 12α-hydroxylase (ambiguous); HCO 12α-hydroxylase. Cat No: EXWM-0970.
7α-Hydroxy Cholesterol
7α-hydroxy Cholesterol is an oxysterol and a precursor in the biosynthesis of the bile acids cholic acid and chenodeoxycholic acid. 7α-Hydroxy Cholesterol is also a secondary metabolite of Cholesterol. 7α-hydroxy Cholesterol (40 μM) increases levels of the adhesion molecules ICAM-1, VCAM-1, and E-selectin in human umbilical vein endothelial cells (HUVECs). Synonyms: cholest-5-ene-3β,7α-diol; 7alpha-hydroxy-cholesterol; 7-alpha-OHC. Grades: > 95%. CAS No. 566-26-7. Molecular formula: C27H46O2. Mole weight: 402.65.
CAP 3
CAP 3 is a cholic acid-peptide conjugate (CAP) with antibacterial activity. It is active against the Gram-negative bacteria E. coli, K. pneumoniae, and A. baumanii (MIC99s = 8, 16, and 16 μM, respectively). CAP 3 increases the fluidity of model Gram-negative bacterial membranes and binds to LPS in vitro. It reduces the biomass and number of colony-forming units in E. coli biofilms in a concentration-dependent manner. CAP 3 inhibits E. coli biofilm formation on catheters implanted in mice infected with E. coli at the incision site when applied as a coating on the catheters. CAP 3 (40 mg/kg) also reduces bacterial load in E. coli-infected wounds in mice. It is cytotoxic to A459 cells (IC50 = 56.4 μM) and has hemolytic activity against human red blood cells with a 50% lysis (HC50) value of 48 μM. Synonyms: CAP 3; CHEMBL5173640; benzyl (4R)-4-[(3R, 5S, 7R, 8R, 9S, 10S, 12S, 13R, 14S, 17R)-3, 7, 12-tris[[2-[(2-amino-3-methylbutanoyl)amino]acetyl]oxy]-10, 13-dimethyl-2, 3, 4, 5, 6, 7, 8, 9, 11, 12, 14, 15, 16, 17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate. Grades: ≥98%. Molecular formula: C52H82N6O11. Mole weight: 967.3.
CHAPS
CHAPS, a derivative of Cholic acid, is a zwitterionic detergent for solubilizing membrane proteins. CHAPS is used for stabilization of various protein-DNA complexes and can retain biochemical activity of proteins in solution [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 75621-03-3. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-15435.
Non-denaturing zwitterionic detergent with cholic acid and sulfobetaine moieties, used to dissolve biological membranes, useful for protein extraction methods due to its ease of removal by dialysis or gel filtration. Low background UV absorption for protein detection.Designed by Good, et al., and typically referred to as Goods buffer useful in cell culture media formulations. Selection of biological buffer systems should include the following criteria: exclusion by biological membranes, low absorption between 240 and 700nm, chemically stable, and stable to temperature and concentration changes. Group: Biochemicals. Alternative Names: (3-[ (3-Cholamidopropyl) dimethylammonio]-1-propanesulfonate) ; N,N-Dimethyl-N-(3-sulfopropyl)-3-[[(3α,5 β, 7α, 12α)-3, 7, 12-trihydroxy-24-oxocholan-24-yl]amino]-1-propanaminium Inner Salt; CHAPS. Grades: Molecular Biology Grade. CAS No. 75621-03-3. Pack Sizes: 5g, 25g, 100g. Molecular Formula: C32H58N2O7S, Molecular Weight: 614.88. US Biological Life Sciences.
Worldwide
CHAPS hydrate
CHAPS hydrate, a derivative of Cholic acid, is a zwitterionic detergent for solubilizing membrane proteins. CHAPS hydrate is used for stabilization of various protein-DNA complexes and can retain biochemical activity of proteins in solution [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 331717-45-4. Pack Sizes: 500 mg; 1 g. Product ID: HY-15435A.
CHAPSO
Non-denaturing zwitterionic detergent with cholic acid and sulfobetaine moieties, used to dissolve biological membranes, useful for protein extraction methods due to its ease of removal by dialysis or gel filtration. Low background UV absorption for protein detection. Group: Biochemicals. Alternative Names: (3-[ (3-Cholamidopropyl) dimethylammonio]-2-hydroxy-1-propanesulfonate) . Grades: Molecular Biology Grade. CAS No. 82473-24-3. Pack Sizes: 5g, 25g. US Biological Life Sciences.
Worldwide
cholate-CoA ligase
Requires Mg2+ for activity. The mammalian enzyme is membrane-bound and catalyses the first step in the conjugation of bile acids with amino acids, converting bile acids into their acyl-CoA thioesters. Chenodeoxycholate, deoxycholate, lithocholate and trihydroxycoprostanoate can also act as substrates. The bacterial enzyme is soluble and participates in an anaerobic bile acid 7 α-dehydroxylation pathway. Group: Enzymes. Synonyms: BAL; bile acid CoA ligase; bile acid co. Enzyme Commission Number: EC 6.2.1.7. CAS No. 9027-90-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5709; cholate-CoA ligase; EC 6.2.1.7; 9027-90-1; BAL; bile acid CoA ligase; bile acid coenzyme A ligase; choloyl-CoA synthetase; choloyl coenzyme A synthetase; cholic thiokinase; cholate thiokinase; cholic acid:CoA ligase; 3α,7α,12α-trihydroxy-5β-cholestanoyl coenzyme A synthetase; 3α,7α,12α-trihydroxy-5β-cholestanoate-CoA ligase; 3α,7α,12α-trihydroxy-5β-cholestanoate-CoA synthetase; THCA-CoA ligase; 3α,7α,12α-trihydroxy-5β-cholestanate-CoA ligase; 3α,7α,12α-trihydroxy-5β-cholestanate:CoA ligase (AMP-forming); cholyl-CoA synthetase; trihydroxycoprostanoyl-CoA synthetase. Cat No: EXWM-5709.
Ethyl Deoxycholate
Ethyl Deoxycholate is the ethyl ester of the common bile salt Deoxycholic Acid (D232645), a Cholic Acid (C432600) derivative used as a component in cell lysis buffers. Group: Biochemicals. Grades: Highly Purified. CAS No. 69519-35-3. Pack Sizes: 100mg, 250mg. Molecular Formula: C26H44O4, Molecular Weight: 420.63. US Biological Life Sciences.
Worldwide
Methyl cholate
Methyl Cholate is methyl ester form of Cholic acid. Cholic acid is one of the major bile acids produced by the liver, where it is synthesized from cholesterol [1]. Uses: Scientific research. Group: Natural products. CAS No. 1448-36-8. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-107830.
Methyl cholatesee
Methyl cholatesee. Group: Biochemicals. Alternative Names: (3a,5b,7a,12a)-3,7,12-Trihydroxycholan-24-oic acid methyl ester; Cholic Acid ?ethyl ?ster; Methyl 3a,7a,12a-trihydroxy-5b-cholan-24-oate. Grades: Highly Purified. CAS No. 1448-36-8. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C25H42O5. US Biological Life Sciences.
Worldwide
Methyl Isolithocholate-d7
Methyl Isolithocholate-d7 is a labelled cholic acid derivative as TGR5 modulator. Found in ox bile, human bile, rabbit bile, and in ox and pig gallstones. Group: Biochemicals. Alternative Names: Methyl 3 β-Hydroxy-5 β-cholanoate; 3 β-Hydroxy-5 β-cholanic Acid Methyl Ester-d7; (3 β,5 β)-3-Hydroxycholan-24-oic Acid Methyl Ester-d7. Grades: Highly Purified. CAS No. 5405-42-5. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
Methyl Lithocholate
Methyl Lithocholate is an derivative of Lithocholic Acid (L469180),a cholic acid derivative as TGR5 modulator. Found in ox bile, human bile, rabbit bile, and in ox and pig gallstones. Group: Biochemicals. Alternative Names: Lithocholic Acid Methyl Ester-d7; Methyl 3α-Hydroxy-5 β-cholan-24-oate-d7; Methyl 3α-Hydroxy-5 β-cholanoate-d7; 3α-Hydroxy-5 β-cholanic Acid-d7; 3α-Hydroxy-5 β-cholan-24-oic Acid Methyl Ester-d7; (3α,5 β)-3-Hydroxycholan-24-oic Acid Methyl Ester-d7. Grades: Highly Purified. CAS No. 1249-75-8. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
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