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Chromanol 293B. Group: Biochemicals. Grades: Purified. CAS No. 163163-23-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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Chromanol 293B
Chromanol 293B is a specific slow delayed rectifier K+ current (IKs) blocker with an IC50 value of 6.89 μM in xenopus oocytes expressing rat. It shows no activity at rat Kv1.1 or Kir2.1 channels at a concentration of 30 μM. It inhibits cystic fibrosis transmembrane conductance regulator (CTFR) Cl- currents (ICTFR) with an IC50 value of 19 μM in xenopus oocytes expressing human CTFR. It increases the extent and rate of IKs in guinea pig ventricular cells in a dose-dependent manner. It is a useful research chemical. Uses: Potassium channel blockers. Synonyms: rel-N-[(3R,4S)-6-cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-N-methyl-ethanesulfonamide; rel-N-[(3R,4S)-6-Cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-N-methylethanesulfonamide; trans-N-[6-Cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-N-methyl-ethanesulfonamide. Grade: ≥99% by HPLC. CAS No. 163163-23-3. Molecular formula: C15H20N2O4S. Mole weight: 324.39.
(-)-[3R,4S]-Chromanol 293B
(-)-[3R,4S]-Chromanol 293B. Group: Biochemicals. Grades: Purified. CAS No. 163163-24-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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(-)-[3R,4S]-Chromanol 293B
(-)-[3R,4S]-Chromanol 293B is one of the chromanols, which inhibits cAMP-mediated Cl- secretion in colon crypts by a blockade of a cAMP-activated K+ conductance. It selectively inhibits the slow component of delayed rectifier K+ current. It has negligible inhibitory action at KV11.1 (hERG) channels. It may be a useful research chemical. Uses: Potassium channel blockers. Synonyms: N-[(3R,4S)-6-Cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-N-methylethanesulfonamide. Grade: ≥99% by HPLC. CAS No. 163163-24-4. Molecular formula: C15H20N2O4S. Mole weight: 324.39.
(2R,4'R,8'S)-α-Tocopherol
(2R,4'R,8'S)-α-Tocopherol is one of the 8 stereoisomers contained in the racemic mixture of synthetic α-Tocopherol, a vitamin E substitute. Synonyms: (2R)-3,4-Dihydro-2,5,7,8-tetramethyl-2-[(4R,8S)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-ol; (R,R,S)-alpha-Tocopherol; (2R)-2,5,7,8-Tetramethyl-2-[(4R,8S)-4,8,12-trimethyltridecyl]-6-chromanol; 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8S)-4,8,12-trimethyltridecyl]-, (2R)-. Grade: >98%. CAS No. 78656-12-9. Molecular formula: C29H50O2. Mole weight: 430.70.
(2R,4'S,8'R)-α-Tocopherol
(2R,4'S,8'R)-α-Tocopherol is one of the 8 stereoisomers contained in the racemic mixture of synthetic α-Tocopherol, a vitamin E substitute. Synonyms: (2R)-2,5,7,8-tetramethyl-2-[(4S,8R)-4,8,12-trimethyltridecyl]-6-chromanol; (R,S,R)-Alpha-Tocopherol; 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-[(4S,8R)-4,8,12-trimethyltridecyl]-, (2R)-; (2R)-3,4-Dihydro-2,5,7,8-tetramethyl-2-[(4S,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-ol. CAS No. 78656-13-0. Molecular formula: C29H50O2. Mole weight: 430.70.
(2R,4'S,8'S)-α-Tocopherol
(2R,4'S,8'S)-α-Tocopherol is one of the 8 stereoisomers contained in the racemic mixture of synthetic α-Tocopherol, a vitamin E substitute. Synonyms: (2R)-3,4-Dihydro-2,5,7,8-tetramethyl-2-[(4S,8S)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-ol; (2R)-2,5,7,8-Tetramethyl-2-[(4S,8S)-4,8,12-trimethyltridecyl]-6-chromanol; 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-[(4S,8S)-4,8,12-trimethyltridecyl]-, (2R)-; (R,S,S)-Alpha-Tocopherol. CAS No. 77171-98-3. Molecular formula: C29H50O2. Mole weight: 430.70.
(2S,4'R,8'R)-α-Tocopherol
(2S,4'R,8'R)-α-Tocopherol is one of the 8 stereoisomers contained in the racemic mixture of synthetic α-Tocopherol, a vitamin E substitute. Synonyms: (2S)-3,4-Dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-ol; (2S)-2,5,7,8-Tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-6-chromanol; 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-, (2S)-. CAS No. 18920-63-3. Molecular formula: C29H50O2. Mole weight: 430.70.
(2S,4'R,8'S)-α-Tocopherol
(2S,4'R,8'S)-α-Tocopherol is one of the 8 stereoisomers contained in the racemic mixture of synthetic α-Tocopherol, a vitamin E substitute. Synonyms: (2S)-3,4-Dihydro-2,5,7,8-tetramethyl-2-[(4R,8S)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-ol; (S,R,S)-α-Tocopherol; (2S)-2,5,7,8-Tetramethyl-2-[(4R,8S)-4,8,12-trimethyltridecyl]-6-chromanol; 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8S)-4,8,12-trimethyltridecyl]-, (2S)-. CAS No. 79434-83-6. Molecular formula: C29H50O2. Mole weight: 430.70.
(2S,4'S,8'R)-α-Tocopherol
(2S,4'S,8'R)-α-Tocopherol is one of the 8 stereoisomers contained in the racemic mixture of synthetic α-Tocopherol, a vitamin E substitute. Synonyms: (2S)-3,4-Dihydro-2,5,7,8-tetramethyl-2-[(4S,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-ol; (S,S,R)-α-Tocopherol; (2S)-2,5,7,8-Tetramethyl-2-[(4S,8R)-4,8,12-trimethyltridecyl]-6-chromanol; 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-[(4S,8R)-4,8,12-trimethyltridecyl]-, (2S)-. CAS No. 79434-82-5. Molecular formula: C29H50O2. Mole weight: 430.70.
(2S,4'S,8'S)-α-Tocopherol
(2S,4'S,8'S)-α-Tocopherol is one of the 8 stereoisomers contained in the racemic mixture of synthetic α-Tocopherol, a vitamin E substitute. Synonyms: (2S)-3,4-Dihydro-2,5,7,8-tetramethyl-2-[(4S,8S)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-ol; 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-[(4S,8S)-4,8,12-trimethyltridecyl]-, (2S)-; (2S)-2,5,7,8-Tetramethyl-2-[(4S,8S)-4,8,12-trimethyltridecyl]-6-chromanol. CAS No. 77171-97-2. Molecular formula: C29H50O2. Mole weight: 430.70.
(2S,4'S,8'S)-β-Tocopherol
(2S,4'S,8'S)-β-Tocopherol is a stereoisomer of one of the naturally occurring forms of Vitamin E. Synonyms: (S,S,S)-β-Tocopherol; (S)-2,5,8-trimethyl-2-((4S,8S)-4,8,12-trimethyltridecyl)chroman-6-ol; (2S)-2,5,8-Trimethyl-2-[(4S,8S)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-1-benzopyran-6-ol; (2S)-2,5,8-Trimethyl-2-[(4S,8S)-4,8,12-trimethyltridecyl]-6-chromanol; 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,8-trimethyl-2-[(4S,8S)-4,8,12-trimethyltridecyl]-, (2S)-. Molecular formula: C28H48O2. Mole weight: 416.68.
(2S)-α-Tocopherol (Mixture of Diastereomers)
(2S)-α-Tocopherol is one of the 8 stereoisomers contained in the racemic mixture of synthetic α-Tocopherol, a vitamin E substitute. Synonyms: (2S)-2,5,7,8-Tetramethyl-2-(4,8,12-trimethyltridecyl)-6-chromanol; 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, (2S)-; (2S)-3,4-Dihydro-2,5,7,8-tetramethyl-2-[4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-ol; (2S,4'RS,8'RS)-α-Tocopherol. CAS No. 1411583-24-8. Molecular formula: C29H50O2. Mole weight: 430.70.
a-DL-Tocopherol Acetate (Vitamin E Acetate)
A form of Vitamin E used in nutritional and dietary supplements. Tocopherols (TCP) (vitamin E) are a series (α, β, γ and δ) of chiral organic molecules that vary in their degree of methylation of the phenol moiety of the chromanol ring. Tocopherols are lipid soluble anti-oxidants that protect cell membranes from oxidative damage. α-Tocopherol is the form of tocopherol preferentially absorbed by homo sapiens. Tocopherol acetate has properties similar but not identical to α-tocopherol. Group: Biochemicals. Alternative Names: Vitamin E Acetate. Grades: Highly Purified. CAS No. 7695-91-2. Pack Sizes: 100g, 250g, 500g. Molecular Formula: C31H52O3. US Biological Life Sciences.
Worldwide
(+)-α-Tocopherol
(+)-α-Tocopherol. Synonyms: 2,5,7,8-Tetramethyl-2-(4',8',12'-trimethyltridecyl)-6-chromanol, 5,7,8-Trimethyltocol, D-α-Tocopherol, Vitamin E. CAS No. 59-02-9. Pack Sizes: 10, 100 g in ampule. Product ID: CDC10-0027. Molecular formula: C29H50O2. Category: Antioxidant Cosmetic Chemicals. Product Keywords: Cosmetic Ingredients; Antioxidant Cosmetic Chemicals; (+)-α-Tocopherol; CDC10-0027; 59-02-9; C29H50O2; 2,5,7,8-Tetramethyl-2-(4',8',12'-trimethyltridecyl)-6-chromanol, 5,7,8-Trimethyltocol, D-α-Tocopherol, Vitamin E; 200-412-2; MFCD00072045; 59-02-9. Purity: >97.0%(GC). Color: Clear yellow to red. EC Number: 200-412-2. Physical State: Viscous Liquid. Solubility: Practically insoluble in water, freely soluble in acetone, in anhydrous ethanol, in methylene chloride and in fatty oils. Quality Level: 200. Storage: -20°C. Boiling Point: 200-220 °C/0.1 mmHg (lit.). Melting Point: 4 °C. Density: 0.95 g/mL at 25 °C (lit.). Product Description: α-Tocopherol is synthesized from γ-tocopherol by the action of enzyme γ-tocopherol methyltransferase. It is the major form of Vitamin E in human plasma. It is present in sunflower seed oil.
α-Tocopherol Acetate.
α-Tocopherol acetate is the most bioactive of the naturally occurring forms of Vitamin E. Richest sources are green vegetables, grains, and oils, particularly palm, safflower and sunflower oils. Group: Biochemicals. Alternative Names: (2R)-3,4-Dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-ol 6-Acetate; Ephynal Acetate; (+)-α-Tocopherol Acetate; (+)-α-Tocopheryl Acetate; (2R,4'R,8'R)-α-Tocopherol Acetate; (2R,4'R,8'R)-α-Tocopheryl Acetate; (R,R,R)-α-Tocopheryl Acetate; 2,5,7,8-Tetramethyl-2-(4,8,12-trimethyltridecyl)-6-chromanol Acetate; Alfacol; Copherol 12250; Ecofrol; Econ; Tofaxin; Tokoferol Acetate. Grades: Highly Purified. CAS No. 58-95-7. Pack Sizes: 1g. US Biological Life Sciences.
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APC-100
APC-100 is an orally available, vitamin E derivative and androgen receptor (AR) antagonist with potential anti-oxidant, chemopreventative and antineoplastic activity. APC-100 binds to ARs in target tissues thereby inhibiting androgen-induced receptor activation and facilitating the formation of inactive complexes that cannot be translocated to the nucleus. APC-100 may ultimately lead to an inhibition of growth in both AR-dependent and AR-independent prostate tumor cells. Uses: Antioxidants. Synonyms: 2,2,5,7,8-Pentamethyl-6-chromanol; Chromanol; 6-Hydroxy-2,2,5,7,8-pentamethylchroman; APC100; 3,4-Dihydro-2,2,5,7,8-pentamethyl-2H-1-Benzopyran-6-ol. Grade: 98%. CAS No. 950-99-2. Molecular formula: C14H20O2. Mole weight: 220.312.
β-Tocotrienol
β-Tocotrienol is isolated from the stem bark of Garcinia virgata. It inhibits the growth of both A549 (GI50=1.38±0.334μM) and U87MG (GI50=2.53±0.604μM) cells at rather low concentrations. β-Tocotrienol can serve as a new anticancer agent for treating human lung and brain cancers. Synonyms: (2R)-3,4-Dihydro-2,5,8-trimethyl-2-[(3E,7E)-4,8,12-trimethyl-3,7,11-tridecatrien-1-yl]-2H-1-benzopyran-6-ol; 2,5,8-Trimethyl-2-(4,8,12-trimethyl-3,7,11-tridecatrienyl)-6-chromanol; D-β-Tocotrienol; ε-Tocopherol; ε-Tokoferol. Grade: 97.5%. CAS No. 490-23-3. Molecular formula: C28H42O2. Mole weight: 410.63.
δ-Tocopherol Acetate
δ-Tocopherol precursor. Group: Biochemicals. Alternative Names: (2R)-3,4-Dihydro-2,8-dimethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-ol 6-Acetate; 2,8-Dimethyl-2-(4,8,12-trimethyltridecyl)-6-chromanol Acetate; δ-Tocopheryl Acetate. Grades: Highly Purified. CAS No. 13027-26-4. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
δ-Tocotrienol
δ-Tocotrienol is from palm oil. Delta-tocotrienol is a potential angiogenic inhibitor that significantly suppresses human colorectal adenocarcinoma cells (DLD-1-CM)-induced tube formation, migration, and adhesion on human umbilical vein endothelial cells. Delta-tocotrienol is a nontoxic activator of mir-34a which can inhibit nonsmall cell lung cancer cells (NSCLC) cell proliferation, induce apoptosis and inhibit invasion, and thus offer a potential starting point for the design of novel anticancer agents. Delta-tocotrienol displays significant radioprotective effects that protects mouse and human hematopoietic progenitors from gamma-irradiation through extracellular signal-regulated kinase/mammalian target of rapamycin signaling. Synonyms: [R-(E,E)]-3,4-Dihydro-2,8-dimethyl-2-(4,8,12-trimethyl-3,7,11-tridecatrienyl)-2H-1-benzopyran-6-ol; (2R)-3,4-Dihydro-2,8-dimethyl-2-[(3E,7E)-4,8,12-trimethyl-3,7,11-tridecatrienyl]-2H-1-benzopyran-6-ol; 2,8-Dimethyl-2-(4,8,12-trimethyl-3,7,11-tridecatrienyl)-6-chromanol; (R)-δ-Tocotrienol; 8-Methyltocotrienol; d-δ-Tocotrienol. Grade: 95%. CAS No. 25612-59-3. Molecular formula: C27H40O2. Mole weight: 396.60.
DL-alpha-Tocopherol
DL-alpha-Tocopherol is a potent antioxidant that protects cell membranes from free radical damage and helps protect organs such as blood vessels, heart, breasts, eyes, skin and glands. Thus it can prevent a variety of chronic diseases, such as breast cancer, cardiovascular disease, rectal cancer and so on. It has the function of anti-oxidation, promoting protein renewal synthesis, regulating platelet adhesion and aggregation. It has the effect of whitening and removing freckles, hair care, sunscreen skin care, improving immune function and delaying aging. Synonyms: 2,5,7,8-Tetramethyl-2-(4,8,12-trimethyltridecyl)-6-Chromanol; (±)-α-Tocopherol; 2,5,7,8-Tetramethyl-2(4',8',12'-trimethyltridecyl)chroman-6-ol; 3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol; all-rac-α-Tocopherol; Vitamim E; Vitamim E Alcohol. Grade: ≥95%. CAS No. 10191-41-0. Molecular formula: C29H50O2. Mole weight: 430.72.
dl-α-Tocopherol Succinate
Dl-α-Tocopherol Succinate is the racemic analog of α-Tocopheryl Succinate. Synonyms: Mono[3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl] Ester Butanedioic Acid; Mono[2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-6-chromanyl] Ester Succinic Acid; 2,5,7,8-Tetramethyl-2-(4,8,12-trimethyltridecyl)-6-chromanol Hydrogen Succinate; DL-α-Tocopherol Succinate; Vitamin E Acid Succinate; Vitamin E Succinate; dl-α-Tocopherol Succinate. Grade: 95%. CAS No. 17407-37-3. Molecular formula: C33H54O5. Mole weight: 530.77.
DL-Vitamin E acetate
Tocopherol acetate is a fat-soluble vitamin that is widely used in a variety of personal care and hygiene products. Vitamin E prevents the oxidation of membranes and unsaturated fatty acids and other easy oxides in cells during the body's metabolism, thus protecting the integrity of cell membranes and preventing aging, and maintaining the normal function of reproductive organs. Tocopherol acetate is a skin conditioner and antioxidant, when used in cosmetic ingredients, it has the protective effect of preventing the sun's ultraviolet rays from damaging the skin. Uses: Vitamins. Synonyms: 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, 6-acetate; 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate; 6-Chromanol, 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate; 2,5,7,8-Tetramethyl-2-(4,8,12-trimethyltridecyl)-6-chromanol Acetate; all-rac-α-tocopheryl acetate. Grade: 98%. CAS No. 7695-91-2. Molecular formula: C31H52O3. Mole weight: 472.75.
HMR 1556
HMR 1556, a chromanol derivative, is a potent I Ks blocker with IC 50 s of 10.5 nM and 34 nM in canine and guinea pig left ventricular myocytes, respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 223749-46-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106369.
Triethylsilane 99+% (GC)
Triethylsilane is a trialkylsilicon hydride used in the synthesis of alkylsilanes via hydrosilation of olefins. Triethylsilane is also used as an effective reducing agent. It acts as a reducing agent in the reduction of 2-chromanols, since it has an active hydride. It acts as a catalyst for redox initiated cationic polymerization, regioselective reductive coupling of enones and allenes, and Beckmann rearrangement of cyclododecanone oxime. It is associated with trifluoroacetic acid and involved in the selective reduction of alkenes. Group: Biochemicals. Alternative Names: NSC 93579; Triethylhydrosilane; Triethylsilicon hydride. Grades: GC. CAS No. 617-86-7. Pack Sizes: 25g, 100g, 250g, 1Kg, 2.5Kg. US Biological Life Sciences.
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