Collagenase Suppliers USA
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Product | Description | |
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Collagenase-Substrate Test Substance (for quantitative Collagenase-Determination) Quick inquiry Where to buy Suppliers range | Collagenase-Substrate Test Substance (for quantitative Collagenase-Determination). Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 837-83-2. Pack Sizes: 1G. Mole weight: 243.26. EC Number: 212-654-6. Catalog: AP837832. | |
Collagenase Quick inquiry Where to buy Suppliers range | Collagenase. Categories: collagenase; ft-0624030. | CA, FL & NJ |
Collagenase Chromophore Substrate Test Substance Quick inquiry Where to buy Suppliers range | Collagenase Chromophore Substrate Test Substance is an enzyme substrate. Synonyms: 4-phenylazobenzyl-oxycarbonyl-l-prolyl-l-leucine; 1-[ ({4-[ (E) -Phenyldiazenyl]phenyl}methoxy) carbonyl]-L-prolyl-L-leucine. CAS No. 98640-71-2. Molecular formula: C25H30N4O5. Mole weight: 466.53. | |
Collagenase from Clostridium histolyticum Quick inquiry Where to buy Suppliers range | 100mg Pack Size. Group: Analytical Reagents, Biochemicals, Building Blocks, Catalysts, Diagnostic Raw Materials, Organics. Formula: N/A. CAS No. 9001-12-1. Prepack ID 90029169-100mg. See USA prepack pricing. | |
Collagenase Inhibitor I Quick inquiry Where to buy Suppliers range | The Collagenase Inhibitor I controls the biological activity of Collagenase. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. Pack Sizes: 5MG. Mole weight: 448.51. Catalog: IAR42415337. Assay: ≥98% (TLC). | |
Collagenase Substrate Quick inquiry Where to buy Suppliers range | Synonyms: Z-Gly-Pro-Gly-Gly-Pro-Ala-OH. Grades: 95%. CAS No. 13075-38-2. Molecular formula: C27H36N6O9. Mole weight: 588.61. | |
72 kDa type IV collagenase (560-568) Quick inquiry Where to buy Suppliers range | 72 kDa type IV collagenase. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-376. | |
(2E) -6-[[ (1, 1-Dimethylethoxy) carbonyl]amino]-2-hexenoic Acid Quick inquiry Where to buy Suppliers range | (2E) -6-[[ (1, 1-Dimethylethoxy) carbonyl]amino]-2-hexenoic Acid is an intermediate in the synthesis of (E)-6-Amino-2-hexenoic Acid, used in the preparation of anti-collagenase active agent. Group: Biochemicals. Alternative Names: (E) -6-[[ (1, 1-Dimethylethoxy) carbonyl]amino]-2-hexenoic Acid. Grades: Highly Purified. CAS No. 145119-17-1. Pack Sizes: 250mg. Molecular Formula: C??H??NO?, Molecular Weight: 229.27. US Biological Life Sciences. | Worldwide |
(2E) -6-[[ (1, 1-Dimethylethoxy) carbonyl]amino]-2-hexenoic Acid Ethyl Ester Quick inquiry Where to buy Suppliers range | (2E) -6-[[ (1, 1-Dimethylethoxy) carbonyl]amino]-2-hexenoic Acid Ethyl Ester is an intermediate in the synthesis of (E)-6-Amino-2-hexenoic Acid (A609990), used in the preparation of anti-collagenase active agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 1008751-73-2. Pack Sizes: 50mg, 250mg. Molecular Formula: C13H23NO4. US Biological Life Sciences. | Worldwide |
2-Hydroxy-1-pyrrolidinecarboxylic Acid 1,1-Dimethylethyl Ester Quick inquiry Where to buy Suppliers range | 2-Hydroxy-1-pyrrolidinecarboxylic Acid 1,1-Dimethylethyl Ester is an intermediate in the synthesis of (E)-6-Amino-2-hexenoic Acid (A609990), used in the preparation of anti-collagenase active agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 84766-91-6. Pack Sizes: 500mg, 5g. Molecular Formula: C9H17NO3. US Biological Life Sciences. | Worldwide |
Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt Quick inquiry Where to buy Suppliers range | It is used as a substrate in a rapid, sensitive, continuous spectrophotometric assay for vertebrate collagenase, gelatinase A, and gelatinase B. Synonyms: Glycine, 1-acetyl-L-prolyl-L-leucylglycyl-2-mercapto-4-methylpentanoyl-L-leucyl-, ethyl ester. CAS No. 98992-65-5. Molecular formula: C31H53N5O8S. Mole weight: 655.85. | |
(-)-Actinonin (N4-Hydroxy-N1-[(1S)-1[[(2S)-2-(hydroxymethyl)-1-pyrroldinyl]carbonyl]-2-methylpropyl]-2-pentyl-,(2R)-(9CI)) Quick inquiry Where to buy Suppliers range | A potent in vivo inhibitor of collagenase. Group: Biochemicals. Alternative Names: N4-Hydroxy-N1-[(1S)-1[[(2S)-2-(hydroxymethyl)-1-pyrroldinyl]carbonyl]-2-methylpropyl]-2-pentyl-,(2R)-(9CI). Grades: Highly Purified. CAS No. 13434-13-4. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
Adenosine (9- β-D-ribofuranosyladenine, Adenine riboside, Adenine-9- β-D-ribofuranoside) Quick inquiry Where to buy Suppliers range | In the extracellular space, ecto-5?-nucleotidase (CD73) dephosphorylates adenosine triphosphate (ATP) to produce adenosine. Adenosine has four receptors namely A1R, A2AR A2BR and A3R. Adenosine plays a key role in the osteogenic differentiation. A1R induces osteoclast differentiation and A2AR induces osteoblast differentiation. Adenosine has been used: as a supplement in embryonic type culture medium for in vitro osteogenic differentiation for evaluation of its effect on cell survival by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT assay) and cell proliferation by 3H-thymidine incorporation assay in multi drug resistant glioblastoma stem-like cells (GSCs), and as a standard in high performance liquid chromatography (HPLC). as a constituent in collagenase solution for the collagenase digestion of mice fat tissue. Group: Biochemicals. Alternative Names: 9- β-D-Ribofuranosyl-9H-purin-6-amine; 9- β-D-Ribofuranosyladenine; Adenine Riboside; Adenocard; Adenocor; Adenogesic; Adenoscan; Adrekar; Boniton; D-Adenosine; 1-(6-Amino-9H-purin-9-yl)-1-deoxy- β-D-ribofuranose; Myocol; NSC 7652. Grades: Molecular Biology Grade. CAS No. 58-61-7. Pack Sizes: 100g, 500g. Molecular Formula: C10H13N5O4, Molecular Weight: 267.25. US Biological Life Sciences. | Worldwide |
Aranciamycin Quick inquiry Where to buy Suppliers range | Antibiotic. Similar to steffimycin. Active against Gram-positive bacteria. Clostridium histolyticum collagenase inhibitor. Antitumor compound. Group: Biochemicals. Grades: Highly Purified. CAS No. 72389-06-1. Pack Sizes: 500ug, 1mg. US Biological Life Sciences. | Worldwide |
Aureoquinone Quick inquiry Where to buy Suppliers range | Aureoquinone is produced by the strain of Aureobasidium sp. The IC50 (μg/mL) for inhibiting the activity of protease, including trypsin, papain, thermophilic protease, collagenase and pound-protease are 11.4?14.5?17.8?7.1?and 8.7 respectively. Synonyms: 2,5,7,8-tetrahydroxy-3,6-dimethylnaphthalene-1,4-dione. Molecular formula: C12H10O6. Mole weight: 250.20. | |
CL 82,198 Quick inquiry Where to buy Suppliers range | CL 82,198 is a selective inhibitor of human collagenase-3, also known as matrix metalloproteinase-13 (MMP-13). It doesn't have effect against MMP-1, MMP-9 or TNF-α converting enzyme. CL 82,198 is also used to evaluate the role of MMP-13 in diverse processes, including cancer cell migration, acute lung injury, and joint degeneration associated with osteoarthritis. Synonyms: CL-82198; N-[4-(4-Morpholinyl)butyl]-2-benzofurancarboxamide. Grades: ≥95%. CAS No. 307002-71-7. Molecular formula: C17H22N2O3. Mole weight: 302.4. | |
Coptisine Chloride Quick inquiry Where to buy Suppliers range | Coptisine is an alkaloid found in Chinese goldthread (Coptis chinensis). A bacterial collagenase inhibitor. Group: Biochemicals. Alternative Names: 6, 7-Dihydrobis[1, 3]benzodioxolo[5, 6-a:4', 5'-g]quinolizinium Chloride. Grades: Highly Purified. CAS No. 6020-18-4. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
FALGPA Quick inquiry Where to buy Suppliers range | Falgpa is a type of synthetic compound that has been used in laboratory experiments for various purposes since its discovery in the 1990s. It is a derivative of the naturally occurring chemical, phenylalanine, and has been found to have a variety of biochemical and physiological effects on living organisms. Synonyms: 2-furanacryloyl-leucyl-glycyl-prolyl-alanine; FA-LEU-GLY-PRO-ALA-OH; FALGPA; COLLAGENASE SUBSTRATE II; N-(3-[2-FURYL]ACRYLOYL)-LEU-GLY-PRO-ALA; N-[3-(2-FURYL)ACRYLOYL]-L-LEUCYL-GLYCYL-L-PROLYL-L-ALANINE; clostridiopeptidase; N-(3-(2-FURYL)ACRYLOYL)-L-LEUCYL-GLY. Grades: >95% by HPLC. CAS No. 78832-65-2. Molecular formula: C23H32N4O7. Mole weight: 476.52. | |
Freselestat Quick inquiry Where to buy Suppliers range | Freselestat is a high affinity and selective human neutrophil elastase 1 (HNE1) inhibitor (Ki = 12 nM) with >100-fold less activity at other related proteases including trypsin, pancreatic elastase, collagenase and murine macrophage elastase. Freselestat can be used as treatment for neutrophil-predominant inflammatory lung diseases. Synonyms: 2-(5-amino-6-oxo-2-phenylpyrimidin-1-yl)-N-[1-(5-tert-butyl-1,3,4-oxadiazol-2-yl)-3-methyl-1-oxobutan-2-yl]acetamide; ONO6818; ONO 6818; ONO-6818. Grades: 95%. CAS No. 208848-19-5. Molecular formula: C23H28N6O4. Mole weight: 452.51. | |
Funalenone Quick inquiry Where to buy Suppliers range | Funalenone is a phenalene compound originally isolated from A. niger. It inhibits HIV-1 integrase and type I collagenase. Funalenone is also a selective inhibitor of matrix metalloproteinase-1 (MMP-1; IC50 = 170 μM). Synonyms: 8-deoxyxanthoherquein; 3,4,7,9-tetrahydroxy-2-methoxy-6-methyl-1H-phenalen-1-one. Grades: ≥95%. CAS No. 259728-61-5. Molecular formula: C15H12O6. Mole weight: 288.25. | |
Funalenone (3,4,7,9-Tetrahydroxy-6-methyl-1H-phenalen-1-one) Quick inquiry Where to buy Suppliers range | Matrix metalloproteinase-1 (MMP-1; Type I collagenase) inhibitor. HIV-1 integrase inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 259728-61-5. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
K-1115A Quick inquiry Where to buy Suppliers range | It is produced by the strain of Streptomyces griseorubiginosus Mer-K1115. K1115A inhibited the direct binding of activator protein-1 (AP-1) to AP-1 oligonucleotide (IC50 = 100 microM), and the production of collagenase in IL-1 alpha-stimulated rat synovial cells (IC50 = 60 microM). Synonyms: K1115 A; 2-Anthracenecarboxylic acid, 9,10-dihydro-3,8-dihydroxy-9,10-dioxo-1-propyl-. CAS No. 208525-17-1. Molecular formula: C18H14O6. Mole weight: 326.30. | |
K1115 B1 Quick inquiry Where to buy Suppliers range | It is a co-produced compound of K-1115A produced by the strain of Streptomyces griseorubiginosus Mer-K1115. K1115 B1 inhibited the direct binding of activator protein-1 (AP-1) to AP-1 oligonucleotide, and the production of collagenase in IL-1 alpha-stimulated rat synovial cells. Synonyms: XR-573. Molecular formula: C22H24O8. Mole weight: 416.42. | |
K1115 B2 Quick inquiry Where to buy Suppliers range | It is a co-produced compound of K-1115A produced by the strain of Streptomyces griseorubiginosus Mer-K1115. K1115 B2 inhibited the direct binding of activator protein-1 (AP-1) to AP-1 oligonucleotide, and the production of collagenase in IL-1 alpha-stimulated rat synovial cells. Molecular formula: C23H26O9. Mole weight: 446.45. | |
Laccaridione A Quick inquiry Where to buy Suppliers range | It is produced by the strain of Laccaria amethystea. It can inhibit the activity of antiserine protease. It inhibits trypsin, papain, thermophilic protease, collagenase and zinc protease with IC50 (μg/mL) of 14.7, 2.5, 18.8, 7.2 and 18.2, respectively. Synonyms: 10-hydroxy-1,7-dimethoxy-3-[(2E)-4-methylhex-2-en-2-yl]-1H-benzo[g]isochromene-8,9-dione; 1H-Naphtho(2,3-C)pyran-8,9-dione, 3-((1E)-1,3-dimethyl-1-penten-1-yl)-10-hydroxy-1,7-dimethoxy-. CAS No. 320369-80-0. Molecular formula: C22H24O6. Mole weight: 384.42. | |
Laccaridione B Quick inquiry Where to buy Suppliers range | It is produced by the strain of Laccaria amethystea. It can inhibit the activity of antiserine protease. It inhibits trypsin, papain, thermophilic protease, collagenase and zinc protease with IC50 (μg/mL) of 10.9, 5.1, 8.4, 5.7 and 3.0, respectively. It also has a strong anti-proliferative activity against L-929, K-562 and HeLa cells with IC50 (μg/mL) of 2.4, 1.8 and 13.9, respectively. Synonyms: 1-ethoxy-10-hydroxy-7-methoxy-3-[(2E)-4-methylhex-2-en-2-yl]-1H-benzo[g]isochromene-8,9-dione; 1H-Naphtho[2,3-c]pyran-8,9-dione, 3-[(1E)-1,3-dimethyl-1-pentenyl]-1-ethoxy-10-hydroxy-7-methoxy-. CAS No. 320369-81-1. Molecular formula: C23H26O6. Mole weight: 398.45. | |
L-Alanine benzyl ester hydrochloride Quick inquiry Where to buy Suppliers range | A benzoxazine derivative used as an additive in the microemulsion formulation for topical applications of acyclovir. A reagent in the preparation of collagenase inhibitors. Synonyms: L-Ala-OBzl HCl; L-Alanine benzyl ester hydrochloride. Grades: ≥ 98% (HPLC). CAS No. 5557-83-5. Molecular formula: C10H13NO2·HCl. Mole weight: 215.90. | |
L-Alanine Benzyl Ester Hydrochloride Quick inquiry Where to buy Suppliers range | A benzoxazine derivative used as an additive in the microemulsion formulation for topical applications of acyclovir. A reagent in the preparation of collagenase inhibitors. Group: Biochemicals. Alternative Names: L-Alanine Phenylmethyl Ester Hydrochloride; (S)-Benzyl 2-aminopropanoate Hydrochloride; Benzyl L-Alaninate Hydrochloride; NSC 523831. Grades: Highly Purified. CAS No. 5557-83-5. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |
Matlystatin A Quick inquiry Where to buy Suppliers range | It is produced by the strain of Actinomadura atramentaria. It's a Type V collagenase inhibitor. It can inhibit type IV collagenase and type I collagenase with ID50 (μmol/L) of 0.3 and 1.2, respectively. It has anti-gram-positive bacteria effect. Synonyms: N-Acetyl-S-(4-(((hexahydro-2-(2-(2-(hydroxyamino)-2-oxoethyl)-1-oxoheptyl)-3-pyridazinyl)carbonyl)amino)-5-methyl-3-oxoheptyl)-L-cysteine; N-acetyl-S- (4- (2- (2- (2- (hydroxyamino) -2-oxoethyl) heptanoyl) hexahydropyridazine-3-carboxamido) -5-methyl-3-oxoheptyl) -L-cysteine. CAS No. 140626-94-4. Molecular formula: C27H47N5O8S. Mole weight: 601.76. | |
Matlystatin B Quick inquiry Where to buy Suppliers range | It is produced by the strain of Actinomadura atramentaria. It's a Type V collagenase inhibitor. It can inhibit type IV collagenase and type I collagenase with ID50 (μmol/L) of 1.43 and 1.2, respectively. It has anti-gram-positive bacteria effect. Synonyms: 1(2H)-Pyridazinebutanamide, tetrahydro-N-hydroxy-6-[[[2-methyl-1-(1-oxopropyl)butyl]amino]carbonyl]-g-oxo-b-pentyl-, [6S-[1(S*),6R*(1R*,2R*)]]-; Matlystatin B1. CAS No. 140923-32-6. Molecular formula: C22H40N4O5. Mole weight: 440.58. | |
Matlystatin D Quick inquiry Where to buy Suppliers range | It is produced by the strain of Actinomadura atramentaria. It's a Type V collagenase inhibitor. It can inhibit type IV collagenase and type I collagenase with ID50 (μmol/L) of 3.64 and 28, respectively. Synonyms: Matlystatin D1; Pyrazolo(1,2-a)pyridazin-4-ium,8-carboxy-1-(1-(((hexahydro-2-(2-(2-(hydroyamino)-2-oxoethyl)-1-oxoheptyl)-3-pyridazinyl)carbonyl)amino)-2-methylbutyl)-5,6,7,8-tetrahydro-,hydroxide,inner salt; [(3-{6-[{[1-(8-Carboxy-5,6,7,8-tetrahydropyrazolo[1,2-a]pyridazin-9-ium-1-yl)-2-methylbutyl]imino}(hydroxy)methyl]-1,2-diazinane-1-carbonyl}-1-hydroxyoctylidene)amino]oxidanide. CAS No. 140638-25-1. Molecular formula: C27H44N6O6. Mole weight: 548.68. | |
Matlystatin E Quick inquiry Where to buy Suppliers range | It is produced by the strain of Actinomadura atramentaria. It's a Type V collagenase inhibitor. It can inhibit type IV collagenase and type I collagenase with ID50 (μmol/L) of 19.3 and 59, respectively. Synonyms: Matlystatin E1; Pyrazolo(1,2-a)pyridazin-4-ium,8-carboxy-1-(1-(((hexahydro-2-(2-(2-(hydroxyamino)-2-oxoethyl)-1-oxohexyl)-3-pyridazinyl)carbonyl)amino)-2-methylbutyl)-5,6,7,8-tetrahydro-,hydroxide,inner salt; [(3-{6-[{[1-(8-Carboxy-5,6,7,8-tetrahydropyrazolo[1,2-a]pyridazin-9-ium-1-yl)-2-methylbutyl]imino}(hydroxy)methyl]-1,2-diazinane-1-carbonyl}-1-hydroxyheptylidene)amino]oxidanide. CAS No. 140638-26-2. Molecular formula: C26H42N6O6. Mole weight: 534.65. | |
Matlystatin F Quick inquiry Where to buy Suppliers range | It is produced by the strain of Actinomadura atramentaria. It's a Type V collagenase inhibitor. It can inhibit type IV collagenase and type I collagenase with ID50 (μmol/L) of 1.82 and 5.1, respectively. Synonyms: Matlystatin F1; Pyrazolo(1,2-a)pyridazin-4-ium,5-carboxy-1-(1-(((hexahydro-2-(2-(2-(hydroyamino)-2-oxoethyl)-1-oxoheptyl)-3-pyridazinyl)carbonyl)amino)-2-methylbutyl)-5,6,7,8-tetrahydro-,hydroxide,inner salt; [(3-{6-[{[1-(5-Carboxy-5,6,7,8-tetrahydropyrazolo[1,2-a]pyridazin-9-ium-1-yl)-2-methylbutyl]imino}(hydroxy)methyl]-1,2-diazinane-1-carbonyl}-1-hydroxyoctylidene)amino]oxidanide. CAS No. 140667-42-1. Molecular formula: C27H44N6O6. Mole weight: 548.68. | |
MMP-13 Inhibitor Quick inquiry Where to buy Suppliers range | MMP-13 Inhibitor is a potent and selective inhibitor of matrix metalloproteinase-13 (MMP-13) with IC50 value of 8 nM. Synonyms: Collagenase-3 Inhibitor; Matrix Metalloproteinase-13 Inhibitor; 4,6-Pyrimidinedicarboxamide; N4,N6-Bis(4-fluoro-3-methylbenzyl)pyrimidine-4,6-dicarboxamide. Grades: ≥98%. CAS No. 544678-85-5. Molecular formula: C22H20F2N4O2. Mole weight: 410.4. | |
MMP-13 Substrate, Fluorogenic Quick inquiry Where to buy Suppliers range | A quenched fluorescence substrate for MMP-13 (collagenase-3; kcat/Km = 1.09 x 10? M?¹s?¹). Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. Pack Sizes: 1MG. Mole weight: 1100.14. Catalog: IAR42416009. Assay: ≥98% (HPLC). | |
MMP-2/MMP-9 Substrate II Quick inquiry Where to buy Suppliers range | An exceptional thiopeptide that is used as a substrate for the rapid, sensitive, and continuous spectrophotometric assay of Type IV collagenases, MMP-2 (gelatinase A), and MMP-9 (gelatinase B). Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. Pack Sizes: 5MG. Mole weight: 655.85. Catalog: IAR42416007. Assay: ≥97% (HPLC). | |
MMP-8 Inhibitor I Quick inquiry Where to buy Suppliers range | MMP-8 Inhibitor I is a selective and cell-permeable inhibitor of matrix metalloproteinase-8 (MMP-8) with IC50 value of 4 nM. MMP-8 is a neutrophil collagenase that cleaves interstitial collagens. MMP-8 is associated with diseases including arthritis, cancer, osteoporosis and arteriosclerosis. Synonyms: Matrix Metalloproteinase-8 Inhibitor I; N-hydroxy-2-(4-methoxyphenyl)sulfonyl-3,4-dihydro-1H-isoquinoline-3-carboxamide. Grades: ≥95%. CAS No. 236403-25-1. Molecular formula: C17H18N2O5S. Mole weight: 362.4. | |
Paquinimod Quick inquiry Where to buy Suppliers range | Paquinimod, also known as ABR - 215757, belonging to the class of quinoline-3-carboxamide derivatives, is a S100A9 inhibitor. Paquinimod is an immunomodulatory compound that reduces pathology in experimental collagenase-induced osteoarthritis. Synonyms: N,5-diethyl-4-hydroxy-1-methyl-2-oxo-N-phenyl-1,2-dihydroquinoline-3-carboxamide; ABR - 215757; ABR 215757; ABR215757; Paquinimod. Grades: 95%. CAS No. 248282-01-1. Molecular formula: C21H22N2O3. Mole weight: 350.42. | |
PZ-Peptide Quick inquiry Where to buy Suppliers range | PZ-Peptide is a chromogenic substrate for the assay of collagenase and thimet oligopeptidase (Pz-peptidase, metalloendopeptidase 24.15, collagenase-like peptidase). Synonyms: 4-Phenylazobenzyloxycarbonyl-L-pro-leu-gly-pro-D-arg dihydrate; Pz-Cpz-Pro-Leu-Gly-Pro-Arg. CAS No. 17011-78-8. Molecular formula: C38H52N10O8. Mole weight: 776.88. | |
Ro 32-3555 Quick inquiry Where to buy Suppliers range | Ro 32-3555 is a selective inhibitor of collagenases over the related human matrix metalloproteinases stromelysin 1, and gelatinases A and B (Ki values of 527, 154 and 59 nM, respectively). It inhibits both the cartilage and bone changes in this mouse model of OA, and thus shows great potential as a treatment of OA in humans. Synonyms: Ro-32-3555; Ro 32 3555; Ro323555; (αR,βR)-β-(Cyclopentylmethyl)-N-hydroxy-γ-oxo-α-[(3,4,4-trimethyl-2,5-dioxo-1-imidazolidinyl)methyl]-1-piperidinebutanamide; Cipemastat; Ro32-3555; 190648-49-8; GFUITADOEPNRML-SJORKVTESA-N; UNII-02HQ4TYQ60; Trocade. Grades: ≥97% by HPLC. CAS No. 190648-49-8. Molecular formula: C22H36N4O5. Mole weight: 436.55. | |
SC-44463 Quick inquiry Where to buy Suppliers range | SC-44463 is an MMP inhibitor, also a collagenase inhibitor , and HDAC inhibitor. Synonyms: SC44463; SC 44463; (R)-N4-hydroxy-2-isobutyl-N1-((S)-3-(4-methoxyphenyl)-1-(methylamino)-1-oxopropan-2-yl)succinamide. CAS No. 104408-38-0. Molecular formula: C19H29N3O5. Mole weight: 379.45. | |
Substance P (7-11) Quick inquiry Where to buy Suppliers range | Substance P fragment. Increases PGE2 and collagenase production. Involved in pain signal transmission. Anti-inflammatory and immunomodulatory agent. Active in vitro and in vivo. Synonyms: H-Phe-Phe-Gly-Leu-Met-NH2; SP(7-11); Phe1-Phe2-Gly3-Leu4-Met5-NH2. Grades: >95%. CAS No. 51165-05-0. Molecular formula: C31H44N6O5S. Mole weight: 612.78. | |
Taxifolin Quick inquiry Where to buy Suppliers range | Taxifolin ((+)-Dihydroquercetin) exhibits important anti-tyrosinase activity. Taxifolin exhibits significant inhibitory activity against collagenase with an IC50 value of 193.3 μM. Taxifolin is an important natural compound with antifibrotic activity. Taxifolin is a free radical scavenger with antioxidant capacity. Group: Biobased Products. Alternative Names: (2R-trans)-2-(3,4-Dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-4-benzopyrone. Grades: 98%. CAS No. 480-18-2. Product ID: BBC480182. Molecular formula: C15H12O7. Mole weight: 304.25. IUPAC Name: (2R,3R)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-2,3-dihydrochromen-4-one. Appearance: Light-yellow powder. Density: 1.33 g/ml. SMILES: C1=CC (=C (C=C1[C@@H]2[C@H] (C (=O)C3=C (C=C (C=C3O2)O)O)O)O)O. | |
WS75624 A Quick inquiry Where to buy Suppliers range | WS75624 A is an endothelin converting enzyme (ECE) inhibitor isolated from the fermentation broth of Saccharothrix sp. No. 75624. It also showed other metalloprotease (collagenase and neutral endopeptidase) inhibitory activity with IC50 value of 1 mM/ml. Synonyms: WS-75624 A; WS 75624 A; WS-75624A. Molecular formula: C18H24N2O5S. Mole weight: 380.5. | |
WS75624 B Quick inquiry Where to buy Suppliers range | WS75624 B is an endothelin converting enzyme (ECE) inhibitor isolated from the fermentation broth of Saccharothrix sp. No. 75624. It also showed other metalloprotease (collagenase and neutral endopeptidase) inhibitory activity with IC50 value of 1 mM/ml. Synonyms: WS-75624 B; WS 75624 B; WS-75624B. Molecular formula: C18H24N2O5S. Mole weight: 380.5. | |
YM-24074 Quick inquiry Where to buy Suppliers range | YM-24074 is a type I collagenase inhibitor isolated from Streptomyces sp. YL-01869P. Synonyms: YM 24074. Molecular formula: C21H38N4O5. Mole weight: 426.6. |