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| Product | Description | |
|---|---|---|
| E3 ligase Ligand-Linker Conjugates 30 | E3 ligase Ligand-Linker Conjugates 30 incorporates a cereblon (CRBN) ligand for the E3 ubiquitin ligase, and a PROTAC linker. E3 ligase Ligand-Linker Conjugates 30 can be used to design PROTAC MDM2 degrade. Synonyms: 4- ( (2- (2- (2- (2-aminoethoxy) ethoxy) ethoxy) ethyl) amino) -2- (2, 6-dioxopiperidin-3-yl) isoindoline-1, 3-dione; Pomalidomide-PEG3-C2-NH2; SCHEMBL19451340; BCP33441; HY-128716; CS-0099510; Cereblon Ligand-Linker Conjugates 5; E3 ligase Ligand-Linker Conjugates 30. Grades: > 98%. CAS No. 2093416-31-8. Molecular formula: C21H28N4O7. Mole weight: 448.47. |  |
| 1,?1-?Dimethylethyl Ester 3-?Bromo-?6-?fluoro-?2-pyridinecarboxylic Acid | 1,?1-?Dimethylethyl Ester 3-?Bromo-?6-?fluoro-?2-pyridinecarboxylic Acid is a useful reagent in preparation of cell peremeable Bcl-xl inhibitor and antibody drug conjugates. Group: Biochemicals. Grades: Highly Purified. CAS No. 1430753-76-6. Pack Sizes: 25mg, 50mg. Molecular Formula: C10H11BrFNO2, Molecular Weight: 276.1. US Biological Life Sciences. |  Worldwide |
| 1-(1H-Benzotriazol-1-yl)-2-(1H-indol-3-yl)ethanone | 1-(1H-Benzotriazol-1-yl)-2-(1H-indol-3-yl)ethanone is an intermediate in the synthesis of amino acid conjugates of indole-3-acetic acid (IAA), which has shown similar binding behavior to to immobilized human serum albumin, and thus can be used as tumor therapeutic. It is also a phytotoxic conjugates of Indole-3-acetic Acid, which are shown to be the potential agents for biochemical selection of plant mutants in conjugate hydrolysis. Group: Biochemicals. Grades: Highly Purified. CAS No. 1080025-88-2. Pack Sizes: 250mg, 500mg. Molecular Formula: C16H12N4O. US Biological Life Sciences. | Worldwide |
| 1,2:3,4-Di-O-isopropylidene-6-O-methacryloyl-a-D-galactopyranose | The 1,2:3,4-Di-O-isopropylidene-6-O-methacryloyl-a-D-galactopyranose compound stands out as an essential element in the synthesis of glycoconjugates. Its application in drug delivery and vaccine development cannot be overstated, given its ability to form multivalent carbohydrate conjugates. Remarkably, the compound boasts inhibitory features on β-galactosidase, a trait instrumental in studying the mechanics of galactosialidosis, a type of lysosomal storage diseases, and understanding the disease's underlying processes. Synonyms: MAGP. CAS No. 2715-36-8. Molecular formula: C16H24O7. Mole weight: 328.36. | |
| 1,3,5,7-Tetramethyl-8-(C3-COOH)4,4-difluoro-4-bora-3a,4a-diaza-s-indacene | BODIPY dyes are used to generate fluorescent conjugates of proteins, nucleotides, oligonucleotides and dextrans, as well as to prepare fluorescent enzyme substrates, fatty acids, phospholipids, lipopolysaccharides, receptor ligands and polystyrene microspheres. Synonyms: 4-(4,4-Difluoro-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indacene-8-yl)-butyric Acid. CAS No. 878674-84-1. Molecular formula: C17H22BF2N2O2. Mole weight: 335.18. | |
| 1,6-Heptadiyne | 1,6-Heptadiyne is a reactant used in the synthesis of neomycin-benzimidazole conjugates to be used for the recognition of HIV-TAR RNA. Group: Biochemicals. Grades: Highly Purified. CAS No. 2396-63-6. Pack Sizes: 1g, 5g. Molecular Formula: C7H8, Molecular Weight: 92.14. US Biological Life Sciences. | Worldwide |
| 1-Azido-1-deoxy-β-D-glucopyranoside tetraacetate | 1-Azido-1-deoxy-β-D-glucopyranoside tetraacetate (CAS# 13992-25-1) is an intermediate used for the synthesis of Protein Tyrosine Phosphatase 1B inhibito1. It is used for the preparation of variously coupled conjugates of D-glucose via click chemistry for inhibition of glycogen phosphorylase. Synonyms: 2,3,4,6-Tetra-O-acetyl-1-deoxy-β-D-glucopyranosyl azide; β-D-Glucopyranosyl Azide 2,3,4,6-Tetraacetate; 1-β-Azido-2,3,4,6-tetraacetyl-D-glucopyranose; 2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl azide; NSC 272456; 1-Azido-1-deoxy-beta-D-glucopyranose tetraacetate; (2R,3R,4S,5R,6R)-2-(Acetoxymethyl)-6-azidotetrahydro-2H-pyran-3,4,5-triyl triacetate. Grades: ≥95%. CAS No. 13992-25-1. Molecular formula: C14H19N3O9. Mole weight: 373.32. | |
| 1-Boc-azetidine-3-carboxylic acid | 1-Boc-azetidine-3-carboxylic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 1-Boc-azetidine-3-carboxylic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 142253-55-2. Pack Sizes: 1 g; 5 g. Product ID: HY-40141. |  |
| 1-Cbz-azetidine-3-carboxylic acid | 1-Cbz-azetidine-3-carboxylic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 1-Cbz-azetidine-3-carboxylic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 97628-92-7. Pack Sizes: 10 g; 25 g. Product ID: HY-W004868. | |
| 1-N-Boc-3-hydroxyazetidine | 1-N-Boc-3-hydroxyazetidine is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 1-N-Boc-3-hydroxyazetidine is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Group: Signaling pathways. CAS No. 141699-55-0. Pack Sizes: 25 g; 50 g. Product ID: HY-40142. | |
| (1R)-Deruxtecan | (1R)-Deruxtecan is a drug-linker conjugates for ADC [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2270986-87-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-13631O. | |
| (1S)-Camphorsultam | Reagent used to make Camphorsultam conjugates. Group: Biochemicals. Alternative Names: (1S)-(-)-10,2-Camphorsultam; (2R)-Bornane-10,2-sultam; Hexahydro-8,8-dimethyl-3H-3a,6-methano-2,1-benzisothiazole. Grades: Highly Purified. CAS No. 94594-90-8. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| 2-(2-(2-Aminoethoxy)ethoxy)acetic acid | H2N-PEG2-CH2COOH belongs to a polyethylene glycol (PEG) linker covalently bound to E3 Ligase binding group (E3LB) and protein binding group (PB). H2N-PEG2-CH2COOH is a PEG derivative containing an amino group with a terminal carboxylic acid. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. PEG Linkers may be useful in the development of antibody drug conjugates and PROTACs. Synonyms: Amino-PEG2-CH2CO2H; Amino-PEG2-CH2COOH; Amino-PEG2-acetic acid. Grades: ≥95%. CAS No. 134978-97-5. Molecular formula: C6H13NO4. Mole weight: 163.17. | |
| 2-[2- (Fmoc-amino) ethoxy]ethylamine Hydrochloride | 2-[2- (Fmoc-amino) ethoxy]ethylamine is an intermediate used to synthesize specific probes for human 5-HT4 receptor dimerization studies. It is also used to prepare doxorubicin-formaldehyde peptide conjugates targeting αv β3 integrin with antitumor activities. Group: Biochemicals. Grades: Highly Purified. CAS No. 221352-88-1. Pack Sizes: 25mg, 50mg. Molecular Formula: C19H23ClN2O3, Molecular Weight: 362.85. US Biological Life Sciences. | Worldwide |
| 2,3,4-Tri-O-acetyl-D-glucuronide methyl ester | 2,3,4-Tri-O-acetyl-D-glucuronide methyl ester is an important pharmaceutical intermediate mainly used in the synthesis of glucuronide conjugates. It assists in the research and development of drugs targeting a wide range of diseases, including cancer and metabolic disorders. Synonyms: Methyl-(2,3,4-tri-O-acetyl-D-glucopyranosyl)uronate. CAS No. 3082-95-9. Molecular formula: C13H18O10. Mole weight: 334.28. | |
| 2,3,4-Tri-O-benzyl-D-glucuronide benzyl ester | 2,3,4-Tri-O-benzyl-D-glucuronide benzyl ester, a preeminent compound employed extensively in the biomedical sector for drug formulation and disease investigation, embodies unparalleled versatility. Its integral role as a precursor in synthesizing glucuronide conjugates significantly contributes to the exploration of drug metabolism. Synonyms: Benzyl (2,3,4-tri-O-benzyl-D-glucopyranosyl)uronate Benzyl 2,3,4-tri-O-benzyl-D-glucuronate 2,3,4-Tris-O-(phenylmethyl)-D-glucuronic acid phenylmethyl ester. CAS No. 53684-90-5. Molecular formula: C34H34O7. Mole weight: 554.63. | |
| 2,4-Dinitrophenyl)-L-lysine hydrochloride monohydrate | 2,4-Dinitrophenyl)-L-lysine hydrochloride monohydrate is a biochemical reagent primarily used in the research of antibody responses to hapten-protein conjugates, contributing to development of immunology and vaccines. Synonyms: Nalpha-2,4-DNP-L-lysine hydrochloride. CAS No. 14401-10-6. | |
| [2- (5-Carboxy-2-ethylpentylcarboxy) ]benzoyl Glucuronide | [2- (5-Carboxy-2-ethylpentylcarboxy) ]benzoyl Glucuronide enhances phthalate metabolites and their glucuronide conjugates temporal and thermal stability in urine. Group: Biochemicals. Grades: Highly Purified. CAS No. 1217463-87-0. Pack Sizes: 500ug, 1mg. Molecular Formula: C22H28O12, Molecular Weight: 484.45. US Biological Life Sciences. | Worldwide |
| 2,6-Diiodo-1,3,5,7-tetramethyl-8-phenyl-4,4-difluoroboradiazasindacene | BODIPY dyes are used to generate fluorescent conjugates of proteins, nucleotides, oligonucleotides and dextrans, as well as to prepare fluorescent enzyme substrates, fatty acids, phospholipids, lipopolysaccharides, receptor ligands and polystyrene microspheres. Synonyms: 5,5-Difluoro-2,8-diiodo-1,3,7,9-tetramethyl-10-phenyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide. CAS No. 1083009-44-2. Molecular formula: C19H17BF2I2N2. Mole weight: 575.974. | |
| 2',6'-Dimethylcarbonylphenyl-10-sulfopropylacridinium-9-carboxylate 4'-NHS ester | 2',6'-Dimethylcarbonylphenyl-10-sulfopropylacridinium-9-carboxylate 4'-NHS ester is a chemiluminescent acridinium ester label used widely in clinical diagnostics, particularly in automated immunochemistry analysers. Acridinium ester labels are also useful research tools for the investigation of protein-carbohydrate interactions to characterise the binding affinity between specific carbohydrate and its binding protein. An example of those are lectin-acridinium ester conjugates used as chemiluminescent probes. Group: Biochemicals. Alternative Names: 9- [ [4- [ [ (2, 5-Dioxo-1-pyrrolidinyl) oxy] carbonyl] -2, 6-dimethylphenoxy] carbonyl] -10- (3-sulfopropyl) acridinium inner salt; 2', 6'-Di methyl -4'- (N-succinimidyl oxycarbonyl ) phenyl -10-sulfopropyl acridinium -9-carboxyl ate; NSP-DMAE-NHS. Grades: Highly Purified. CAS No. 194357-64-7. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C30H26N2O9S, Molecular Weight: 590.6. US Biological Life Sciences. | Worldwide |
| 2-Aminophenyl 2,3,4-Tri-O-acetyl-β-D-glucuronide Methyl Ester | 2-Aminophenyl 2,3,4-Tri-O-acetyl-β-D-glucuronide Methyl Ester is an esteemed biomedicine, serving as an indispensible precursor. It facilitates the synthesis of drug and compound glucuronide conjugates, pivotal in the intricate process of drug detoxification and elimination. Molecular formula: C19H23NO10. Mole weight: 425.39. | |
| [2-Carboxy (2-carboxymethyl) hexyl]benzoyl Glucuronide | [2-Carboxy (2-carboxymethyl) hexyl]benzoyl Glucuronide enhances phthalate metabolites and their glucuronide conjugates temporal and thermal stability in urine. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C22H28O12, Molecular Weight: 484.45. US Biological Life Sciences. | Worldwide |
| 2'-Deoxy-3,5-dimethylcytidine | 2'-Deoxy-3,5-dimethylcytidine is involved in the biosynthesis of albomycin δ2 for the purpose of providing a template for assembling siderophore and aminoacyl-tRNA synthetase inhibitor conjugates. Group: Biochemicals. Grades: Highly Purified. CAS No. 198198-29-7. Pack Sizes: 1mg, 5mg. Molecular Formula: C11H17N3O4, Molecular Weight: 255.27. US Biological Life Sciences. | Worldwide |
| (2-Ethoxy-4-formylphenoxy)acetic Acid | (2-Ethoxy-4-formylphenoxy)acetic Acid is synthetic reagent, vanillin derivative. It can be used as reagent/reactant for synthetic preparation. Design, synthesis, and biological evaluation of thiazolidine-2,4-dione conjugates as PPAR-γ agonists for use in diabetes treatment. Group: Biochemicals. Grades: Highly Purified. CAS No. 51264-76-7. Pack Sizes: 100mg, 500mg. Molecular Formula: C11H12O5, Molecular Weight: 224.21. US Biological Life Sciences. | Worldwide |
| 2-Octadecyleicosanoic Acid | 2-Octadecyleicosanoic acid is used as a reagent to synthesize Lipid Oligonucleitide Conjugates, compounds that act as a drug delivery system to mutated/infected cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 108293-08-9. Pack Sizes: 250mg, 2.5g. Molecular Formula: C38H76O2, Molecular Weight: 565.01. US Biological Life Sciences. | Worldwide |
| 2-Octadecyleicosanoic Acid Ethyl-d5 Ester | 2-Octadecyleicosanoic Acid Ethyl-d5 Ester is labelled 2-Octadecyleicosanoic Acid Ethyl Ester (O235965) which is the ethyl ester of 2-Octadecyleicosanoic acid (O235960) which is used as a reagent to synthesize Lipid Oligonucleitide Conjugates, compounds that act as a drug delivery system to mutated/infected cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 100mg. Molecular Formula: C40H75D5O2, Molecular Weight: 598.09. US Biological Life Sciences. | Worldwide |
| 2-Octadecyleicosanoic Acid Ethyl Ester | 2-Octadecyleicosanoic Acid Ethyl Ester is the ethyl ester of 2-Octadecyleicosanoic acid (O235960) which is used as a reagent to synthesize Lipid Oligonucleitide Conjugates, compounds that act as a drug delivery system to mutated/infected cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500mg, 5g. Molecular Formula: C40H80O2, Molecular Weight: 593.059999999999. US Biological Life Sciences. | Worldwide |
| 2-Octadecyleicosanoic Acid Methyl-d3 Ester | 2-Octadecyleicosanoic Acid Methyl-d3 Ester is labelled 2-Octadecyleicosanoic Acid Methyl Ester (O235970), the Methyl Ester of 2-Octadecyleicosanoic acid (O235960) which is used as a reagent to synthesize Lipid Oligonucleitide Conjugates, compounds that act as a drug delivery system to mutated/infected cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 100mg. Molecular Formula: C39H75D3O2, Molecular Weight: 582.049999999999. US Biological Life Sciences. | Worldwide |
| 2-Octadecyleicosanoic Acid Methyl Ester | 2-Octadecyleicosanoic Acid Methyl Ester is the Methyl Ester of 2-Octadecyleicosanoic acid (O235960) which is used as a reagent to synthesize Lipid Oligonucleitide Conjugates, compounds that act as a drug delivery system to mutated/infected cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 507241-47-6. Pack Sizes: 500mg, 5g. Molecular Formula: C39H78O2, Molecular Weight: 579.04. US Biological Life Sciences. | Worldwide |
| 2-Phenylglycine | 2-Phenylglycine is used as a reagent in the synthesis of benzoquinone-amino acid conjugates which have antibacterial activity. Synonyms: DL-α-Phenylglycine; (±)-α-Aminophenylacetic acid; (RS)-2-Phenylglycine; (±)-Phenylglycine; (±)-α-Phenylglycine; 2-Amino-2-phenylacetic Acid; C-Phenylglycine; DL-2-Phenylglycine; DL-Phenylglycine; NSC 24619; NSC 32070; NSC 7928; α-Aminobenzeneacetic Acid. Grades: > 95%. CAS No. 2835-6-5. Molecular formula: C8H9NO2. Mole weight: 151.17. | |
| (2R,4R)-4-Hydroxypyrrolidine-2-carboxylic acid hydrochloride | cis-4-Hydroxy-D-proline hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). cis-4-Hydroxy-D-proline hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Group: Signaling pathways. CAS No. 77449-94-6. Pack Sizes: 25 g; 100 g. Product ID: HY-76104. | |
| (2R,4S)-1-(tert-Butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic acid | N-tert-Butoxycarbonyl-trans-4-hydroxy-D-proline is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-tert-Butoxycarbonyl-trans-4-hydroxy-D-proline is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Group: Signaling pathways. CAS No. 147266-92-0. Pack Sizes: 5 g; 10 g; 25 g. Product ID: HY-77593. | |
| 2'-Triethylsilyldocetaxel | Used in the preparation of ester-linked docetaxel-monosaccharide conjugates. Group: Biochemicals. Alternative Names: (αR, βS)- β -[[ (1, 1-Dimethylethoxy) carbonyl]amino]-α -[ (triethylsilyl) oxy]-benzenepropanoic Acid (2aR, 4S, 4aS, 6R, 9S, 11S, 12S, 12aR, 12bS)-12b-(Acetyloxy)-12-(benzoyloxy)-2a, 3, 4, 4a, 5, 6, 9, 10, 11, 12, 12a, 12b-dodecahydro-4, 6, 11-trihydroxy-4a, 8, 13, 13-tetramethyl-5-oxo-7, 11-methano-1H-cyclodeca[3, 4]benz[1, 2-b]oxet-9-yl Ester. Grades: Highly Purified. CAS No. 162871-12-7. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| 3,5-Dimethoxyiodobenzene. | Intermediate for the synthesis of glucuronide conjugates of trans-Resveratrol. Group: Biochemicals. Alternative Names: 1,3-Dimethoxy-5-iodobenzene; 1-Iodo-3,5-dimethoxybenzene; 3,5-Dimethoxy-1-iodobenzene; 3,5-Dimethoxyphenyl Iodide. Grades: Highly Purified. CAS No. 25245-27-6. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| 3-Allyloxy-1,2-propanediol | 3-Allyloxy-1,2-propanediol is a useful synthetic intermediate. It is used to prepare doxorubicin analogs. It is also used to synhesize poly(ethylene glycol)-lipid conjugates suitable for use in drug delivery. Group: Biochemicals. Grades: Highly Purified. CAS No. 123-34-2. Pack Sizes: 1g, 5g. Molecular Formula: C6H12O3, Molecular Weight: 132.16. US Biological Life Sciences. | Worldwide |
| 3-Allyloxy-1,2-propanediol-d5 | 3-Allyloxy-1,2-propanediol-d5 is labelled 3-Allyloxy-1,2-propanediol (A569020) which is used to prepare doxorubicin analogs. It is also used to synhesize poly(ethylene glycol)-lipid conjugates suitable for use in drug delivery. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C6H7D5O3, Molecular Weight: 137.19. US Biological Life Sciences. | Worldwide |
| 3-amino-2,6-piperidinedione hydrochloride | 3-Aminopiperidine-2,6-dione hydrochloride is a reagent for preparing lenalidomide that can induce ubiquitination and degradation of CK1α in del(5q) MDS. It can also be used to prepare phthalimide conjugates that can promote ligand-dependent target protein degradation. Synonyms: 3-Amino-2,6-piperidinedione Monohydrochloride; 2-Amino-glutarimide Hydrochloride; 3-Amino-2,6-dioxopiperidine Hydrochloride; 3-Aminopiperidine-2,6-dione Monohydrochloride; DL-Glutamic Acid Imide Hydrochloride; Glutamimide Hydrochloride; 2,6-dioxopiperidine-3-ammonium chloride; Glutamic acid imide hydrochloride; Glutamic acid imide-DL-hydrochloride; ACMC-20a23n; (+-)-3-Amino-2,6-piperidinedione monohydrochloride; AMPD00004; 3-Aminopiperidine-2,6-dione, HCl. Grades: > 99 %. CAS No. 24666-56-6. Molecular formula: C5H9ClN2O2. Mole weight: 164.59. | |
| 3-Amino-5,6-dichloro-2-pyrazinecarboxylic Acid Methyl Ester | 3-Amino-5,6-dichloro-2-pyrazinecarboxylic Acid Methyl Ester, is used for the preparation of 2-Amidino analogs of glycine-Amiloride (A578700) conjugates, acting as inhibitors of the protease urokinase plasminogen activator (uPA), a promising anticancer targets. Group: Biochemicals. Grades: Highly Purified. CAS No. 1458-18-0. Pack Sizes: 1g, 2.5g. Molecular Formula: C6H5Cl2N3O2. US Biological Life Sciences. | Worldwide |
| 3-Azidopropyl 2,3,4,6-tetra-O-acetyl-b-D-galactopyranoside | 3-Azidopropyl 2,3,4,6-tetra-O-acetyl-b-D-galactopyranoside is a valuable compound acting as a precursor in the research and development of carbohydrate-based molecules and conjugates. This compound is frequently employed in the development of targeted drug delivery systems and glycan-based therapies. Molecular formula: C17H25N3O10. Mole weight: 431.39. | |
| 3-Bodipy-propanoic acid | BODIPY dyes are used to generate fluorescent conjugates of proteins, nucleotides, oligonucleotides and dextrans, as well as to prepare fluorescent enzyme substrates, fatty acids, phospholipids, lipopolysaccharides, receptor ligands and polystyrene microspheres. Synonyms: BDP FL carboxylic acid;4,4-Difluoro-5,7-dimethyl-3-(2-carboxyethyl)-4-bora-3a,4a-diaza-S-indacene; 7-(2-carboxyethyl)-5,5-difluoro-1,3-dimethyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide; BDP FL acid; BODIPY FL. Grades: 95%. CAS No. 165599-63-3. Molecular formula: C14H15BF2N2O2. Mole weight: 292.093. | |
| 3-Carboxyumbelliferyl b-D-glucuronide | 3-Carboxyumbelliferyl b-D-glucuronide is a biochemical compound commonly used in the biomedical industry. This product is utilized for studying glucuronidase activity and drug metabolism. It serves as a substrate in enzymatic assays to measure the hydrolysis of glucuronide conjugates. CAS No. 216672-17-2. Molecular formula: C16H14O11. Mole weight: 382.28. | |
| 3'-Cholesterol CPG 1000 | 3'-Cholesterol CPG 1000 is a highly sought-after phosphoramidite building block, coveted by experts in the field for its impressive versatility and usefulness. Boasting numerous applications within the biomedical industry, its primary function is in the synthesis of oligonucleotides with cholesterol conjugates. Scientists and researchers alike utilize this remarkable product in their study of lipoprotein metabolism, and its effectiveness in the treatment of hypercholesterolemia-associated diseases such as atherosclerosis cannot be overstated. | |
| 4-[(Carbobenzoxyamino)methyl]benzoic acid | 4-[(Carbobenzoxyamino)methyl]benzoic acid is an intermediate used in the preparation of paclitaxel-camptothecin conjugates with antitumor properties. Synonyms: Z-(4)Ambz-OH; Z-HN-CH2-Ph(4)-COOH; 4- ( ([ (Benzyloxy) carbonyl]amino) methyl) benzoic Acid. Grades: 95%. CAS No. 58933-52-1. Molecular formula: C16H15NO4. Mole weight: 285.30. | |
| 4-Formyl-2-methoxyphenyl β-D-Glucopyranosiduronic Acid Triacetate Methyl Ester | Used in the preparation of epothilone-saccharide conjugates for the treatment of proliferative diseases. Group: Biochemicals. Grades: Highly Purified. CAS No. 704885-44-9. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| 4- (Maleimido) benzophenone | A sulfhydryl reactive heterobifunctional photocrosslinking reagent. It generates photoactivatable conjugates from thiols. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| 4-Methylphenyl 2-O-acetyl-3-O-benzyl-4-O-Fmoc-b-D-glucopyranuronic acid methyl ester | 4-Methylphenyl 2-O-acetyl-3-O-benzyl-4-O-Fmoc-b-D-glucopyranuronic acid methyl ester, which unveils unparalleled possibilities in the realm of biomedical advancements. This remarkable molecule lies at the forefront of fostering novel derivatives of glucopyranuronic acid, boasting an intricate chemical arrangement. It stands as a prospective contender in disease treatment, as it exerts its influence on vital biochemical pathways. Delving even deeper, this compound exhibits immense potential in the realms of targeted drug delivery systems and therapeutic drug conjugates. Molecular formula: C38H36O10. Mole weight: 652.70. | |
| (5)6-Carboxytetramethylrhodamine | (5)6-Carboxytetramethylrhodamine contains a carboxylic acid that can be used to react with primary amines via carbodiimide activation of the carboxylic acid; bright, orange-fluorescent dye produces conjugates with absorption/emission maxima of ~555/580 nm [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 117557-83-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-D0934. | |
| 5-Amino-5-deoxy-1,2-O-isopropylidene-6-O-trityl-α-D-galactofuranose | 5-Amino-5-deoxy-1,2-O-isopropylidene-6-O-trityl-α-D-galactofuranose is a synthetic carbohydrate intermediate that exhibits immense potential in the production of glyco-conjugates by providing significant advantages in terms of chemical stability and intramolecular cation binding. This complex compound is widely used in the synthesis of Cluster A glycopeptide epitopes, including trimeric structures, which can be utilized as potential vaccine candidates against the notorious bacterial pathogen, Staphylococcus aureus. Synonyms: 5-Amino-5-deoxy-1,2-O-(1-methylethylidene)-6-O-(triphenylmethyl)-α-D-galactofuranose. CAS No. 109681-00-7. Molecular formula: C28H31NO5. Mole weight: 461.55. | |
| 5'-Amino-Modifier C6 PDA | 5'-Amino-Modifier C6 PDA, a versatile chemical compound, finds its application in the biomedical industry for manipulating DNA and RNA molecules. Through its special reactive group, it efficiently conjugates with nucleic acid strands, successfully combating diseases such as cancer and genetic disorders. Its implications in the development of anti-sense oligonucleotides and siRNA command admiration among researchers and scientists. Its unique properties not only aid in unraveling complex mechanisms but also pave the path for developing novel therapies. Grades: >95% by HPLC. Molecular formula: C24H39N4O4P. Mole weight: 478.57. | |
| 5-FAM SE | 5-FAM SE is a single isomer, is a fluorescent labeling reagent used for labeling peptides, proteins and nucleotides. 5-FAM SE can react with amines and can yield stable amine conjugates [1] [2]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 92557-80-7. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15938. | |
| 5-Iodoresorcinol | Intermediate for the synthesis of glucuronide conjugates of trans-Resveratrol. Group: Biochemicals. Alternative Names: 1,3-Dihydroxy-5-iodobenzene; 3,5-Dihydroxyiodobenzene; 3,5-Dihydroxyphenyl Iodide; 5-Iodo-1,3-benzenediol. Grades: Highly Purified. CAS No. 64339-43-1. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| 5'-O-DMT-thymidine-3'-lcaa-CPG | 5'-O-DMT-thymidine-3'-lcaa-CPG, an essential modified nucleotide, has garnered tremendous interest in the realm of biomedical research. Its purpose lies in the synthesis of oligonucleotides, granting researchers an unparalleled advantage in their studies. These resulting oligonucleotide conjugates play a pivotal role in the development of groundbreaking drug delivery systems, exhibiting immense potential as therapeutic agents targeting a plethora of diseases, including the infamous cancer and insidious viral infections. Synonyms: DMT-T-lcaa-CPG. | |
| 6-Azido-6-deoxy-1,2-O-isopropylidene-a-D-glucofuranose | 6-Azido-6-deoxy-1,2-O-isopropylidene-a-D-glucofuranose, a critically significant compound employed in biomedical research, exhibits immense promise in therapeutic applications. Its exceptional attributes find utility in the production of antiviral medications, effectively combatting multiple viral infections. Leveraging its azido group, this compound facilitates effortless labeling and conjugation with diverse molecules, thus enabling the development of advanced drug delivery platforms and bioconjugates for the identification and management of diseases. Synonyms: 6-Azido-6-deoxy-1,2-O-isopropylidene-alpha-D-glucofuranose; (3aR,5R,6S,6aR)-5-[(1R)-2-azido-1-hydroxyethyl]-2,2-dimethyl-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-6-ol; (3aR,5R,6S,6aR)-5-[(1R)-2-azido-1-hydroxyethyl]-2,2-dimethyl-tetrahydro-2H-furo[2,3-d][1,3]dioxol-6-ol; 6-Azido-6-deoxzy-1,2-o-isopropylidene-a-D-glucofuranose; A-D-GLUCOFURANOSE,6-AZIDO-6-DEOXY-1,2-O-(1-METHYLETHYLIDENE)-; (3aR,5R,6S,6aR)-5-((R)-2-azido-1-hydroxyethyl)-2,2-dimethyltetrahydrofuro[3,2-d][1,3]dioxol-6-ol. CAS No. 65371-16-6. Molecular formula: C9H15N3O5. Mole weight: 245.23. | |
| 6-Azidohexanoic acid NHS ester | A noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Synonyms: N3-C5-NHS ester. Grades: ≥ 95% (HPLC). CAS No. 866363-70-4. Molecular formula: C10H14N4O4. Mole weight: 254.24. | |
| 8(4'-bromophenyl)-1,3,5,7-tetramethyl-BODIPY | BODIPY dyes are used to generate fluorescent conjugates of proteins, nucleotides, oligonucleotides and dextrans, as well as to prepare fluorescent enzyme substrates, fatty acids, phospholipids, lipopolysaccharides, receptor ligands and polystyrene microspheres. Synonyms: 8-(4-Bromophenyl)-4,4-difluoro-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indacene. CAS No. 850534-66-6. Molecular formula: C19H18BBrF2N2. Mole weight: 403.077. | |
| AEEA-AEEA | AEEA-AEEA is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Synonyms: 17-amino-10-oxo-3,6,12,15-tetraoxa-9-azaheptadecan-1-oic acid. CAS No. 1143516-05-5. Molecular formula: C12H24N2O7. Mole weight: 308.33. | |
| AF488 azide | AF488 is a fluorescent dye. AF488 is a fluorophore pH-insensitive over a broad pH range (from 4 to 10). It has an absorption maximum at 495 nm and an emission maximum at 519 nm in the green spectrum region. The dye is hydrophilic and can be used to introduce the fluorescent label into various molecules, including proteins and antibodies. Conjugates of molecules with AF488 have high brightness and photostability and are commonly used in flow cytometry and microscopy. This allows the detection of biological objects with high sensitivity at a longer imaging time.,AF488 azide interacts with alkynyl derivatives of biomolecules in Click Chemistry reactions either in the presence of copper (I) catalyst (with terminal alkynes) or without catalyst (with cyclooctynes), leading to the formation of stable adducts. Grades: NMR 1H, HPLC-MS (95%). CAS No. 1679326-36-3 (with azidohexyl group). Molecular formula: C36H56N8O10S2. Mole weight: 825.01. | |
| AF594 activated ester, 5-isomer | AF594 is a bright water-soluble dye that is not sensitive to pH changes within the range from 4 to 10. This red-fluorescent dye is the best alternative to Texas Red, so it is commonly used for flow cytometry and fluorescent microscopy.,AF594 activated ester is used for labeling proteins, peptides, antibodies, and any molecules containing an -NH2 group (such as amino-modified oligonucleotides); it results in the formation of stable amide bonds between the dye and the target molecule. The best result in conjugation reaction achieved at pH from 7 to 9.,AF594 can be used for protein labeling with a high molar dye-to-protein ratio. The resulting conjugates with a high degree of labeling (DOL) do not exhibit significant fluorescence quenching. In contrast, the conjugates have brighter fluorescence, which allows increasing the lowest limit of detection of the labeled product. Grades: NMR 1H, HPLC-MS (95%). CAS No. 1638544-48-5. Molecular formula: C51H67N5O13S2. Mole weight: 1022.23. | |
| α-Glucametacin-d4 | Labelled α-Glucametacin. A nonsteroidal anti-inflammatory analgesic. An indomethacin conjugates with D-glucosamine was prepared for reducing ulcerogenic potency, increasing the bioavailability of indomethacin and exerting the coordinative effects on osteoarthritis. Synonyms: 2-[[[1-(4-Chlorobenzoyl-d4)-5-methoxy-2-methyl-1H-indol-3-yl]acetyl]amino]-2-deoxy-α-D-Glucopyranose; α-Glucametacine-d4; α-Glucamethacin-d4; α-Indomethacin-d4 Glucosamide. Molecular formula: C25H23D4ClN2O8. Mole weight: 522.97. | |
| Alternariol 9-Monomethyl Ether | Alternariol Monomethyl Ether is a mycotoxins found in subsistence farmed maize. Also, it is a natural mycotoxin isolated from the fermentation broth of Trichoderma sp. Jing-8 with phytotoxic, antibacterial and antioxidant activities. Also, it is derived from 3,5-Dimethoxyiodobenzene (D460640), which is an intermediate for the synthesis of glucuronide conjugates of trans-Resveratrol. Group: Biochemicals. Grades: Highly Purified. CAS No. 23452-05-3. Pack Sizes: 5mg, 10mg. Molecular Formula: C15H12O5, Molecular Weight: 272.25. US Biological Life Sciences. | Worldwide |
| Aminooxy-modifier CEP | Aminooxy-modifier CEP is used in oxime ligation for peptide-oligonucleotide conjugates, attachment of nucleosides to solid supports, and head to tail cyclization of oligonucleotides. Group: Biochemicals. Grades: Highly Purified. CAS No. 1393581-75-3. Pack Sizes: 5mg, 10mg. Molecular Formula: C47H58N3O11P, Molecular Weight: 871.95. US Biological Life Sciences. | Worldwide |
| Amino-PEG3-t-butyl acetate | NH2-PEG3-C1-Boc is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 5 can be used in the synthesis of a series of PROTACs. NH2-PEG3-C1-Boc is a PEG derivative containing an amino group with a t-butyl protected carboxyl group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The t-butyl protected carboxyl group can be deprotected under acidic conditions. PEG Linkers may be useful in the development of antibody drug conjugates, PROTACs and drug delivery methods. Synonyms: NH2-PEG3-C1-Boc; PROTAC Linker 5; Amino-PEG3-CH2CO2-t-butyl ester; H2N-PEG3-CH2COOtBu; Acetic acid, 2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester. Grades: >95%. CAS No. 189808-70-6. Molecular formula: C12H25NO5. Mole weight: 263.33. | |
| Amino-PEG4-alcohol | Amino-PEG4-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Amino-PEG4-alcohol is also a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Group: Amino peg linkers. Alternative Names: 11-Amino-3,6,9-trioxaundecanol. CAS No. 86770-74-3. Molecular formula: C8H19NO4. Mole weight: 193.24. Appearance: Liquid. Purity: >90%. IUPACName: 2-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]ethanol. Canonical SMILES: C(COCCOCCOCCO)N. Density: 1.1±0.1 g/cm3. Catalog: ACM86770743. |  |
| Amino-PEG4-CH2COOH | Amino-PEG4-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Amino-PEG4-CH2COOH is also a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Group: Amino peg linkers. Alternative Names: Amino-PEG4-acetic acid. CAS No. 195071-49-9. Molecular formula: C10H21NO6. Mole weight: 251.28. Appearance: Liquid. Purity: >90%. IUPACName: 2-[2-[2-[2- (2-Aminoethoxy) ethoxy]ethoxy]ethoxy]acetic acid. Canonical SMILES: C(COCCOCCOCCOCC(=O)O)N. Density: 1.156±0.06 g/cm3. Catalog: ACM195071499. | |
| Amino-PEG6-alcohol | Amino-PEG6-OH is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Group: Amino peg linkers. Alternative Names: Amino-PEG6-OH. CAS No. 39160-70-8. Molecular formula: C12H27NO6. Mole weight: 281.35. Appearance: Liquid. Purity: >90%. IUPACName: 2-[2-[2-[2-[2- (2-Aminoethoxy) ethoxy]ethoxy]ethoxy]ethoxy]ethanol. Canonical SMILES: C(COCCOCCOCCOCCOCCO)N. Density: 1.1±0.1 g/cm3. Catalog: ACM39160708. | |
| ATFB-SE | A useful protective group in antibody drug conjugates. Synonyms: N-Succinimidyl 4-Azido-2,3,5,6-tetrafluorobenzoate;4-azido-2,3,5,6-tetrafluorobenzoic acid 2,5-dioxo-pyrrolidin-1-yl ester. Grades: ≥98%. CAS No. 126695-58-7. Molecular formula: C11H4F4N4O4. Mole weight: 332.17. | |
| Auristatin F | Auristatin F, a synthetic analog of dolastatin 10, is a cytotoxic tubulin modifier with potent and selective antitumor activity. It is an MMAF analog and cytotoxin in Antibody-drug conjugates. Uses: Adcs cytotoxin. Synonyms: N,N-Dimethyl-L-valyl-L-valyl-(3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino)heptanoyl-(αR,βR,2S)-β-methoxy-α-methyl-2-pyrrolidinepropanoyl-L-phenylalanine; L-Valinamide, N,N-dimethyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1S)-1-carboxy-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-; N,N-Dimethyl-L-valyl-N-[(3R,4S,5S)-1-{(2S)-2-[(1R,2R)-3-{[(1S)-1-carboxy-2-phenylethyl]amino}-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl}-3-methoxy-5-methyl-1-oxo-4-heptanyl]-N-methyl-L-valinamide. Grades: ≥97% by HPLC. CAS No. 163768-50-1. Molecular formula: C40H67N5O8. Mole weight: 745.99. | |
| Azetidine-3-carboxylic acid | Azetidine-3-carboxylic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azetidine-3-carboxylic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2. Uses: Scientific research. Group: Signaling pathways. CAS No. 36476-78-5. Pack Sizes: 10 g; 25 g. Product ID: HY-Y0530. | |
| Azido-PEG10-amine | Azido-PEG10-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a non-cleavable 9 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Synonyms: N3-PEG10-CH2CH2NH2; 32-Azido-3,6,9,12,15,18,21,24,27,30-decaoxadotriacontan-1-amine; O-(2-Aminoethyl)-O-(2-azidoethyl)nonaethylene Glycol; N3-PEG10-NH2. Grades: >97%. CAS No. 912849-73-1. Molecular formula: C22H46N4O10. Mole weight: 526.62. | |
| Azido-PEG3-NHS ester | N3-PEG3-C2-NHS ester is a nonclaevable 3-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs). Group: Azido peg linkers. Alternative Names: N3-PEG3-C2-NHS ester. CAS No. 1245718-89-1. Molecular formula: C13H20N4O7. Mole weight: 344.32. Appearance: Solid or viscous liquid. Purity: >90%. IUPACName: (2,5-Dioxopyrrolidin-1-yl) 3-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]propanoate. Canonical SMILES: C1CC (=O)N (C1=O)OC (=O)CCOCCOCCOCCN=[N+]=[N-]. Catalog: ACM1245718891. | |
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