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500mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C21H30O4. CAS No. 50-22-6. Prepack ID 18552197-500mg. Molecular Weight 346.46. See USA prepack pricing.
Corticosterone
Corticosterone (17-Deoxycortisol) is an orally active and adrenal cortex-produced glucocorticoid, which plays an important role in regulating neuronal functions of the limbic system (including hippocampus, prefrontal cortex, and amygdala). Corticosterone increases the Rab -mediated AMPAR membrane traffic via SGK -induced phosphorylation of GDI. Corticosterone also interferes with the maturation of dendritic cells and shows a good immunosuppressive effect [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: 17-Deoxycortisol; 11β,21-Dihydroxyprogesterone; Kendall's compound B. CAS No. 50-22-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-B1618.
Corticosterone. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4-Pregnene-11β,21-diol-3,20-dione. Product Category: Promotional Products. Appearance: solid. CAS No. 50-22-6. Molecular formula: C21H30O4. Mole weight: 346.46. Purity: 95+%. IUPACName: (8S,9S,10R,11S,13S,14S,17S)-11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one. Product ID: ACM50226-1. Alfa Chemistry ISO 9001:2015 Certified.
Corticosterone
Extract from the adrenal cortex, is a sensitive inhibitor of monoamine transport. Uses: A sensitive inhibitor of monoamine transport. Synonyms: Corticosterone; BRN 2339601; BRN-233960; BRN233960; CCRIS 6753; CCRIS-6753; CCRIS6753; NSC 9705; NSC-9705; NSC9705; (8S,9S,10R,11S,13S,14S,17S)-11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one. Grades: ≥98%. CAS No. 50-22-6. Molecular formula: C21H30O4. Mole weight: 346.46.
corticosterone 18-monooxygenase
This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2 with reduced iron-sulfur protein as one donor, and incorporation o one atom of oxygen into the other donor. The systematic name of this enzyme class is corticosterone,reduced-adrenal-ferredoxin:oxygen oxidoreductase (18-hydroxylating). Other names in common use include corticosterone 18-hydroxylase, and corticosterone methyl oxidase. This enzyme participates in c21-steroid hormone metabolism. Group: Enzymes. Synonyms: corticosterone 18-hydroxylase; corticosterone methyl oxidase. Enzyme Commission Number: EC 1.14.15.5. CAS No. 37256-75-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0948; corticosterone 18-monooxygenase; EC 1.14.15.5; 37256-75-0; corticosterone 18-hydroxylase; corticosterone methyl oxidase. Cat No: EXWM-0948.
Corticosterone 21-acetate
Corticosterone 21-acetate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 11β,21-Dihydroxy-4-pregnene-3,20-dione 21-Acetate; [2-[(8S,9S,10R,11S,13S,14S,17S)-11-hydroxy-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate. Product Category: Steroidal Compounds. CAS No. 1173-26-8. Molecular formula: C23H32O5. Mole weight: 388.5. Purity: 0.98. IUPACName: [2-[(8S,9S,10R,11S,13S,14S,17S)-11-hydroxy-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl]acetate. Canonical SMILES: CC(=O)OCC(=O)C1CCC2C1(CC(C3C2CCC4=CC(=O)CCC34C)O)C. Density: 1.2g/cm³. ECNumber: 214-635-8. Product ID: ACM1173268. Alfa Chemistry ISO 9001:2015 Certified. Categories: Corticosterone acetate.
Corticosterone 21-Acetate
Corticosterone derivative. An intermediate in the biosynthesis of aldosterone, isolated from the adrenal cortex. Group: Biochemicals. Alternative Names: Cort A; NSC 81764; SKF 5654; (11 β)-21-(Acetyloxy)-11-hydroxy-pregn-4-ene-3,20-dione. Grades: Highly Purified. CAS No. 1173-26-8. Pack Sizes: 50mg. US Biological Life Sciences.
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Corticosterone 21-Carboxylic Acid
Corticosterone 21-Carboxylic Acid. Group: Biochemicals. Alternative Names: (11 β)-11-Hydroxy-3,20-dioxo-pregn-4-en-21-oic Acid. Grades: Highly Purified. CAS No. 33762-00-4. Pack Sizes: 10mg. Molecular Formula: C21H28O5, Molecular Weight: 360.44. US Biological Life Sciences.
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Corticosterone-21-hemisuccinate
Corticosterone-21-hemisuccinate. Uses: Designed for use in research and industrial production. Product Category: Steroidal Compounds. CAS No. 10215-77-7. Molecular formula: C25H34O7. Mole weight: 446.54. Purity: 0.95. IUPACName: 4-[2-[(8S,9S,10R,11S,13S,14S,17S)-11-hydroxy-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethoxy]-4-oxobutanoicacid. Canonical SMILES: CC12CCC(=O)C=C1CCC3C2C(CC4(C3CCC4C(=O)COC(=O)CCC(=O)O)C)O. Product ID: ACM10215777. Alfa Chemistry ISO 9001:2015 Certified.
Corticosterone-d8 (Major)
Labeled Corticosterone. Glucocorticoid; an intermediate in the biosynthesis of aldosterone, isolated from the adrenal cortex. Group: Biochemicals. Alternative Names: (11 β)-11,21-Dihydroxy-pregn-4-ene-3,20-dione-d8; 11,21-Dihydroxyprogesterone-d8; 17-Deoxycortisol-d8; 4-Pregnene-11 β,21-diol-3,20-dione-d8; Corticosteron-d8; Kendall's compound B-d8; NSC 9705-d8. Grades: Highly Purified. CAS No. 1271728-07-4. Pack Sizes: 5mg. US Biological Life Sciences.
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Corticosterone impurity 1
Corticosterone impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 20287-97-2. Molecular Formula: C21H28O4. Mole Weight: 344.45. Catalog: APB20287972.
Corticosterone impurity 2
Corticosterone impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2394-25-4. Molecular Formula: C20H28O4. Mole Weight: 332.44. Catalog: APB2394254.
11-Dehydrocorticosterone
11-Dehydrocorticosterone. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Corticosterone,11-dehydro; 17-Deoxycortisone; Kendalls compound A; Dehydrocorticosterone; Cortisone,17-deoxy; 17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthrene-3,11-dione; 21-hydroxypregn-4-ene-3,11,20-trione; 4-pregnene-21-ol-3,11,20-trione; Corticosterone,dehydro; 21-hydroxy-4-pregnene-3,11,20-trione; Dehydrocortocicosterone; 11-Dehydrocorticosteron. Product Category: Steroidal Compounds. CAS No. 72-23-1. Molecular formula: C21H28O4. Mole weight: 344.44. Purity: 0.95. IUPACName: 11-dehydrocorticosterone. Density: 1.21g/cm³. Product ID: ACM72231. Alfa Chemistry ISO 9001:2015 Certified.
11-Dehydrocorticosterone (17-α, β Mixture)
11-Dehydrocorticosterone (α, β mixture) is a precursor to corticosterone (C695700), converted by 11 β-hydroxysteroid dehydrogenase type 1 (11 β-HSD1) which plays a role in glucocorticoid-induced insulin resistance. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 25mg. Molecular Formula: C21H28O4. US Biological Life Sciences.
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11-Deoxy-18-hydroxycorticosterone
11-Deoxy-18-hydroxycorticosterone is an analog of Corticosterone (C695700); a glucocorticoid and intermediate in the biosynthesis of Aldosterone (A514700) which is an adrenocortical steroid isolated from the adrenal cortex. Group: Biochemicals. Grades: Highly Purified. CAS No. 379-68-0. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C21H30O4, Molecular Weight: 346.46. US Biological Life Sciences.
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11-Deoxy corticosterone
11-Deoxy corticosterone. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Desoxycortone, Cortexone, Desossicortone, Desoxicortonum, Deoxycortone, desoxycorticosterone, 11-Deoxycorticosterone, 21-Hydroxyprogesterone, Deoxycorticosterone, Desoxycorticosteronum, 11-Desoxycorticosterone, Reichstein Q, Reichsteins substance Q, Kendalls desoxy compound B, 11-Dcortic, Desossicortone [DCIT], 11-Dehydroxycorticosterone, 4-Pregnen-21-ol-3,20-dione, Corticosterone, 11-deoxy-, Progesterone, 21-hydroxy-. Product Category: Steroidal Compounds. Appearance: white to creamy-white crystalline powder. CAS No. 64-85-7. Molecular formula: C21H30O3. Mole weight: 330.46. Purity: 0.95. IUPACName: (8S,9S,10R,13S,14S,17S)-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one. Canonical SMILES: CC12CCC3C(C1CCC2C(=O)CO)CCC4=CC(=O)CCC34C. Density: 1.15 g/cm³. ECNumber: 200-596-4. Product ID: ACM64857. Alfa Chemistry ISO 9001:2015 Certified.
11-Deoxy Corticosterone
A mineralocorticoid that occurs in adrenal cortex. It acts as a precursor to Aldosterone. Group: Biochemicals. Grades: Highly Purified. CAS No. 64-85-7. Pack Sizes: 10mg, 50mg, 100mg, 500mg. Molecular Formula: C??H??O?. US Biological Life Sciences.
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11-Deoxy Corticosterone-d7
Labelled Deoxycorticosterone. A mineralocorticoid that occurs in adrenal cortex. It acts as a precursor to Aldosterone (A514700). Group: Biochemicals. Alternative Names: 21-Hydroxypregn-4-ene-3,20-dione-d7; 11-Deoxycorticosterone-d7; 11-Dehydroxy-corticosterone-d7; 11-Desoxycorticosterone-d7; 21-Hydroxy-3,20-dioxopregn-4-ene-d7; 21-Hydroxy-4-pregnane-3,20-dione-d7. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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11-Deoxy Corticosterone-d8
Labeled Deoxycorticosterone. A mineralocorticoid that occurs in adrenal cortex. It acts as a precursor to Aldosterone. Group: Biochemicals. Alternative Names: 21-Hydroxypregn-4-ene-3,20-dione-d8; 11-Deoxycorticosterone-d8; 11-Dehydroxy-corticosterone-d8; 11-Desoxycorticosterone-d8; 21-Hydroxy-3,20-dioxopregn-4-ene-d8; 21-Hydroxy-4-pregnane-3,20-dione-d8. Grades: Highly Purified. CAS No. 55487-63-3. Pack Sizes: 1mg. US Biological Life Sciences.
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11-Deoxy Corticosterone Pivalate
11-Deoxycorticosterone Pivalate is a mineralocorticoid hormone and an analog of desoxycorticosterone. 11-Deoxycorticosterone Pivalate is used in the treatment of adrenocortical insufficiency. It is used to treat in patients suffering from rheumatoid arthritis. Group: Biochemicals. Alternative Names: 21-(2,2-dimethyl-1-oxopropoxy)pregn-4-ene-3,20-dione; 11-Deoxycorticosterone Pivalate; 21-Hydroxypregn-4-ene-3,20-dione pivalate; Cortexone M; DOCP; DTMA; Deoxycorticosterone Trimethylacetate; Deoxycortone Pivalate; Deoxycortone Trimethylacetate; Desoxycorticosterone Pivalate; Desoxycortisone pivalate; Desoxycortone pivalate; NSC 95278; Neodin-Depositum; Percorten M; Percorten Pivalate. Grades: Highly Purified. CAS No. 808-48-0. Pack Sizes: 10mg. US Biological Life Sciences.
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16-Hydroxycorticosterone 20-Hydroxy-21-Acid (Mixture of Diastereomers)
16-Hydroxycorticosterone 20-Hydroxy-21-Acid is an oxidized derivative of corticosterone (007040), an intermediate in the biosynthesis of aldosterone (001762), isolated from the adrenal cortex. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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18-Hydroxycorticosterone
18-Hydroxycorticosterone. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (8S,9S,10R,11S,13R,14S,17S)-11-hydroxy-17-(2-hydroxyacetyl)-13-(hydroxymethyl)-10-methyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one; 18-Hydroxy Corticosterone; EINECS 209-221-9; 11beta,18,21-Trihydroxypregn-4-ene-3,20-dione. Product Category: Steroidal Compounds. CAS No. 561-65-9. Molecular formula: C21H30O5. Mole weight: 362.47. Purity: 0.95. IUPACName: (8S,9S,10R,11S,13R,14S,17S)-11-hydroxy-17-(2-hydroxyacetyl)-13-(hydroxymethyl)-10-methyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one. Canonical SMILES: CC12CCC(=O)C=C1CCC3C2C(CC4(C3CCC4C(=O)CO)CO)O. ECNumber: 209-221-9. Product ID: ACM561659. Alfa Chemistry ISO 9001:2015 Certified.
19-Nordeoxycorticosterone
Corticosterone derivative/degradation product. 19-Nordeoxycorticosterone can be used in biological study of correlation between pregnanesteroid conformation, renal mineralocorticoid receptor affinity, and anti-natriuretic effect. Group: Biochemicals. Grades: Highly Purified. CAS No. 4682-70-6. Pack Sizes: 25mg, 100mg. Molecular Formula: C20H28O3, Molecular Weight: 316.43. US Biological Life Sciences.
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20-Dihydro-corticosterone 21-Carboxylic Acid
20-Dihydro-corticosterone 21-Carboxylic Acid. Group: Biochemicals. Alternative Names: 11 β,20-Dihydroxy-3-oxopregn-4-en-21-oic Acid. Grades: Highly Purified. CAS No. 75879-79-7. Pack Sizes: 10mg. US Biological Life Sciences.
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21-Dehydrocorticosterone
21-Dehydrocorticosterone is a metabolite of Corticosterone, a glucocorticoid. Synonyms: 11-Hydroxy-3,20-dioxo-pregn-4-en-21-al; Pregn-4-en-21-al, 11β-hydroxy-3,20-dioxo- (7CI,8CI); 11β-Hydroxy-3,20-dioxo-4-pregnen-21-al. Grades: > 95%. CAS No. 20287-97-2. Molecular formula: C21H28O4. Mole weight: 344.44.
11beta-Hydroxyprogesterone is a potent inhibitors of 11β-Hydroxysteroid dehydrogenase and can confer mineralocorticoid activity on corticosterone in the rat in vivo. 11beta-Hydroxyprogesterone also activates human mineralocorticoid receptor in COS-7 cells with anED50of 10 nM. Synonyms: (8S,9S,10R,11S,13S,14S,17S)-17-acetyl-11-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one; 11OHP compound; Duralutin; Gesterol; Hy-Gestrone; Hylutin; Hyprogest; Pergestron; pregn-4-ene-11 beta-ol-3,20-dione; Pro-Depo; Prodrox; 11β-Hydroxyprogesterone. CAS No. 600-57-7. Molecular formula: C21H30O3. Mole weight: 330.46.
17-Dehydroxy Prednisolone
17-Dehydroxy Prednisolone. Group: Biochemicals. Alternative Names: 1, 2-Dide hydrocorticosterone; 1-Dehydrocorticosterone; 11 β,21-Dihydroxypregna-1,4-diene-3,20-dione; 17-Deoxyprednisolone; Δ1-Corticosterone. Grades: Highly Purified. CAS No. 13479-38-4. Pack Sizes: 250mg. Molecular Formula: C21H28O4, Molecular Weight: 344.44. US Biological Life Sciences.
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17-Dehydroxy Prednisolone-d8
17-Dehydroxy Prednisolone-d8. Group: Biochemicals. Alternative Names: 1, 2-Dide hydrocorticosterone; 1-Dehydrocorticosterone; 11 β,21-Dihydroxypregna-1,4-diene-3,20-dione; 17-Deoxyprednisolone; Δ1-Corticosterone. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C21H20D8O4, Molecular Weight: 352.49. US Biological Life Sciences.
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17-Deoxycortolone
17-Deoxycortolone, is a metabolite of Corticosterone (C695700), an intermediate in the biosynthesis of aldosterone, isolated from the adrenal cortex. Group: Biochemicals. Grades: Highly Purified. CAS No. 600-68-0. Pack Sizes: 1mg. Molecular Formula: C21H34O4, Molecular Weight: 350.49. US Biological Life Sciences.
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21-Hydroxypregnenolone
21-Hydroxypregnenolone is an essential intermediate in corticosterone synthesis. Uses: Scientific research. Group: Natural products. CAS No. 1164-98-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-113020.
21-O-Acetyl 6a-hydroxy cortisol
21-O-Acetyl 6a-hydroxy cortisol. Group: Biochemicals. Alternative Names: 6a,17-Dihydroxy-corticosterone 21-acetate; (6a,11b)-21-(Acetyloxy)-6,11,17-trihydroxy-pregn-4-ene-3,20-dione; 6a,11b,17,21-Tetrahydroxy-pregn-4-ene-3,20-dione 21-acetate. Grades: Highly Purified. CAS No. 67012-81-1. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C23H32O7. US Biological Life Sciences.
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21-O-Acetyl 6α-Hydroxy Cortisol
Protected Cortisol metabolite. Group: Biochemicals. Alternative Names: 6α,17-Dihydroxy-corticosterone 21-Acetate; (6α,11 β)-21-(Acetyloxy)-6,11,17-trihydroxy-pregn-4-ene-3,20-dione; 6α,11 β,17,21-Tetrahydroxy-pregn-4-ene-3,20-dione 21-Acetate. Grades: Highly Purified. CAS No. 67012-81-1. Pack Sizes: 1mg. US Biological Life Sciences.
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21-O-Acetyl 6α-Hydroxy Cortisol-d4
A labeled, protected Cortisol metabolite. Group: Biochemicals. Alternative Names: 6α,17-Dihydroxy-corticosterone 21-Acetate-d4; (6α,11 β)-21-(Acetyloxy)-6,11,17-trihydroxy-pregn-4-ene-3,20-dione-d4; 6α,11 β,17,21-Tetrahydroxy-pregn-4-ene-3,20-dione 21-Acetate-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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21-O-Acetyl 6β-hydroxy cortisol
21-O-Acetyl 6β-hydroxy cortisol. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 6β,17-Dihydroxy-corticosterone 21-Acetate; (6β,11β)-21-(Acetyloxy)-6,11,17-trihydroxy-pregn-4-ene-3,20-dione; 6β,11β,17,21-Tetrahydroxy-pregn-4-ene-3,20-dione 21-Acetate. Product Category: Heterocyclic Organic Compound. Appearance: Light Yellow Solid. CAS No. 13096-53-2. Molecular formula: C23H32O7. Mole weight: 420.5. Purity: 0.96. IUPACName: [2-oxo-2-[(6R,8S,9S,10R,11S,13S,14S,17R)-6,11,17-trihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]ethyl] acetate. Canonical SMILES: CC(=O)OCC(=O)C1(CCC2C1(CC(C3C2CC(C4=CC(=O)CCC34C)O)O)C)O. Product ID: ACM13096532. Alfa Chemistry ISO 9001:2015 Certified.
21-O-Acetyl 6 β-Hydroxy Cortisol
Protected Cortisol metabolite. Group: Biochemicals. Alternative Names: 6 β,17-Dihydroxy-corticosterone 21-Acetate; (6 β,11 β)-21-(Acetyloxy)-6,11,17-trihydroxy-pregn-4-ene-3,20-dione; 6 β,11 β,17,21-Tetrahydroxy-pregn-4-ene-3,20-dione 21-Acetate. Grades: Highly Purified. CAS No. 13096-53-2. Pack Sizes: 5mg. US Biological Life Sciences.
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21-O-Acetyl 6 β-Hydroxy Cortisol-d4
A labeled, protected Cortisol metabolite. Group: Biochemicals. Alternative Names: 6 β,17-Dihydroxy-corticosterone 21-Acetate-d4; (6 β,11 β)-21-(Acetyloxy)-6,11,17-trihydroxy-pregn-4-ene-3,20-dione-d4; 6 β,11 β,17,21-Tetrahydroxy-pregn-4-ene-3,20-dione 21-Acetate-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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21-O-Acetyl 6b-hydroxy cortisol
21-O-Acetyl 6b-hydroxy cortisol. Group: Biochemicals. Alternative Names: 6b,17-Dihydroxy-corticosterone 21-acetate; (6b,11b)-21-(Acetyloxy)-6,11,17-trihydroxy-pregn-4-ene-3,20-dione; 6b,11b,17,21-Tetrahydroxy-pregn-4-ene-3,20-dione 21-acetate. Grades: Highly Purified. CAS No. 13096-53-2. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C23H32O7. US Biological Life Sciences.
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3-oxo-5α-steroid 4-dehydrogenase (NADP+)
The enzyme catalyses the conversion of assorted 3-oxo-Δ4 steroids into their corresponding 5α form. Substrates for the mammalian enzyme include testosterone, progesterone, and corticosterone. Substrates for the plant enzyme are brassinosteroids such as campest-4-en-3-one and (22α)-hydroxy-campest-4-en-3-one. cf. EC 1.3.99.5, 3-oxo-5α-steroid 4-dehydrogenase (acceptor). Group: Enzymes. Synonyms: cholestenone 5α-reductase; testosterone Δ4-5&. Enzyme Commission Number: EC 1.3.1.22. CAS No. 37255-34-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1297; 3-oxo-5α-steroid 4-dehydrogenase (NADP+); EC 1.3.1.22; 37255-34-8; cholestenone 5α-reductase; testosterone Δ4-5α-reductase; steroid 5α-reductase; 3-oxosteroid Δ4-dehydrogenase; 5α-reductase; steroid 5α-hydrogenase; 3-oxosteroid 5α-reductase; testosterone Δ4-hydrogenase; 4-ene-3-oxosteroid 5α-reductase; reduced nicotinamide adenine dinucleotide phosphate:Δ4-3-ketosteroid 5α-oxidoreductase; 4-ene-5α-reductase; Δ4-3-ketosteroid 5α-oxidoreductase; cholest-4-en-3-one 5α-reductase; testosterone 5α-reductase; 3-oxo-5α-steroid 4-dehydrogenase. Cat No: EXWM-1297.
4-Pregnen-21-ol-3,20-dione-2,2,4,6,6,17alpha,21,21-d8. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4-PREGNEN-21-OL-3,20-DIONE-2,2,4,6,6,17ALPHA,21,21-D8;4-Pregnen-2-ol-3,20-dione-2,2,4,6,6,17alpha,21,21-D8;Deoxy Corticosterone-d8. Product Category: Heterocyclic Organic Compound. Appearance: White Solid. CAS No. 55487-63-3. Molecular formula: C21H22D8O3. Mole weight: 338.51. Purity: 96 atom % D. IUPACName: (8S,9S,10R,13S,14S,17S)-2,2,4,6,6,17-hexadeuterio-17-(2,2-dideuterio-2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-3-one. Canonical SMILES: CC12CCC3C(C1CCC2C(=O)CO)CCC4=CC(=O)CCC34C. Product ID: ACM55487633. Alfa Chemistry ISO 9001:2015 Certified. Categories: 11-Deoxy Corticosterone-d8.
6a-Hydroxy cortisol
6a-Hydroxy cortisol. Group: Biochemicals. Alternative Names: 6a,17-Dihydroxy-corticosterone; 6a,11b,17,21-Tetrahydroxy-pregn-4-ene-3,20-dione; NSC 79099. Grades: Highly Purified. CAS No. 2242-98-0. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C21H30O6. US Biological Life Sciences.
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6α-Hydroxy Cortisol
A metabolite of Cortisol. Group: Biochemicals. Alternative Names: 6α,17-Dihydroxy-corticosterone; 6α,11 β,17,21-Tetrahydroxy-pregn-4-ene-3,20-dione; NSC 79099. Grades: Highly Purified. CAS No. 2242-98-0. Pack Sizes: 1mg, 2mg, 5mg, 10mg. US Biological Life Sciences.
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6α-Hydroxy Cortisol-d4
A labeled metabolite of Cortisol. Group: Biochemicals. Alternative Names: 6α,17-Dihydroxy-corticosterone-d4; 6α,11 β,17,21-Tetrahydroxy-pregn-4-ene-3,20-dione-d4; NSC 79099-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
6beta-Hydroxy Cortisol
6beta-Hydroxy Cortisol. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 6beta-Hydroxyhydrocortisone, 6beta,11beta,17alpha,21-Tetrahydroxypregn-4-ene-3,20-dione, Pregn-4-ene-3,20-dione, 6,11,17,21-tetrahydroxy-, (6beta,11beta)-,6beta,11beta,17,21-Tetrahydroxypregn-4-ene-3,20-dione, (6beta,11beta)-6,11,17,21-Tetrahydroxypregn-4-ene-3,20-dione, NSC 76163, 6beta,11beta,17alpha,21-Tetrahydroxypregn-4-en-3,20-dione, Pregn-4-ene-3,20-dione, 6beta,11beta,17,21-tetrahydroxy- (8CI), Hydrocortisone Imp. D (EP), Corticosterone, 6beta,17-dihydroxy- (6CI), 6beta-Hydroxycortisol, 6beta,11beta,17alpha,21-Tetrahydroxy-4-pregen-3,20-dione, 6beta,17-Dihydroxycorticosterone. CAS No. 53-35-0. IUPAC Name: (6R,8S,9S,10R,11S,13S,14S,17R)-6,11,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one. Molecular Formula: C21H30O6. Mole Weight: 378.46. Catalog: APS53350. SMILES: C[C@]12CCC (=O)C=C1[C@H] (O)C[C@H]3[C@@H]4CC[C@] (O) (C (=O)CO)[C@@]4 (C)C[C@H] (O)[C@H]23. Format: Neat.
6β-Hydroxycortisone
6β-Hydroxycortisone can be used as a probe to detect inhibition of CYP3A4 in vivo. Synonyms: (6β)-6,17,21-Trihydroxy-pregn-4-ene-3,11,20-trione; 11-Dehydro-6β,17-dihydroxy-corticosterone; 6β,17,21-Trihydroxy-pregn-4-ene-3,11,20-trione; 6β,17α,21-Trihydroxy-4-pregnene-3,11,20-trione; NSC 15457. Grades: > 95%. CAS No. 16355-28-5. Molecular formula: C21H28O6. Mole weight: 376.44.
6-Methyl Pergolide
6-Methyl Pergolide is a dopamine agonist. It is also a potent antagonist of 5-HT2A and 5-HT2B receptors on porcine cardiac valves. It increases serum corticosterone concentration in rats at a dose of 3 mg/kg. It also activates brain dopaminergic receptors and lowers cranial DOPAC levels in rats. Uses: 6-methyl pergolide activates brain dopaminergic receptors and lowers cranial dopac levels. Synonyms: LY 116467; LY-116467; LY116467; (8β )-6-Methyl-8-[(methylthio)methyl]ergoline; LY062; LY116467; (6aR, 9R, 10aR)-7-methyl-9-(methylsulfanylmethyl)-6, 6a, 8, 9, 10, 10a-hexahydro-4H-indolo[4, 3-fg]quinoline; LY-116467; 6-Methyl-8-((methylthio)methyl)ergoline (8beta). Grades: 98%. CAS No. 57202-76-3. Molecular formula: C17H22N2S. Mole weight: 286.43.
Atumelnant
CRN04894 (compound 17h) is an orally active MC2R antagonist that demonstrates in vivo efficacy in rat model of adrenocorticotropic hormone (ACTH)-stimulated corticosterone secretion[1]. CRN04894 binds to human or rat MC2R with K B values of 0.34 nM and 0.23 nM, respsectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CRN04894. CAS No. 2392970-97-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-158081.
Cortexolone
Cortexolone. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 11-Deoxycortisol; 11-deoxy-17-hydroxy-corticosterone; CORTEXOLONE; 11-Deoxy-17-hydroxycorticosterone; Reichsteins substance S; 17,21-Dihydroxy-pregn-4-ene-3,20-dione; 17α,21-Dihydroxy-4-pregnene-3,20-dione; CORTODOXONE; 11-DESOXYCORTISOL; Cortexolone; skf3050; Reichsteins Substance S; Reichstein S; 11-dioxycortisol; 11-dioxy-cortiso. Product Category: Steroidal Compounds. Appearance: Crystalline Solid. CAS No. 152-58-9. Molecular formula: C21H30O4. Mole weight: 346.46. Purity: 0.98. IUPACName: 11-deoxycortisol. Density: 1.22g/cm³. Product ID: ACM152589. Alfa Chemistry ISO 9001:2015 Certified.
Corticostatin 1
Corticostatin 1 is from Oryctolagus cuniculus. It has microbicidal activity and inhibits corticotropin (ACTH) stimulated corticosterone production. Synonyms: Antiadrenocorticotropin peptide I.
Corticostatin-6
Corticostatin-6 is from Oryctolagus cuniculus. It has microbicidal activity and inhibits corticotropin (ACTH) stimulated corticosterone production.
d[Cha4]-AVP is a selective and potent human vasopressin V1B receptor agonist with Ki value of 1.2 nM. It stimulates corticosterone and ACTH secretion. It shows negligible vasopressor activity in vivo. Synonyms: 3-Mercaptopropionyl-Tyr-Phe-b-cyclohexyl-Ala-Asn-Cys-Pro-Arg-Gly-NH2; (Deamino-Cys¹,β-cyclohexyl-Ala?,Arg?)-Vasopressin. CAS No. 500170-27-4. Molecular formula: C50H71N13O11S2. Mole weight: 1094.31.
Δ4-3-oxosteroid 5β-reductase
The enzyme from human efficiently catalyses the reduction of progesterone, androstenedione, 17α-hydroxyprogesterone and testosterone to 5β-reduced metabolites; it can also act on aldosterone, corticosterone and cortisol, but to a lesser extent. The bile acid intermediates 7α,12α-dihydroxy-4-cholesten-3-one and 7α-hydroxy-4-cholesten-3-one can also act as substrates. Group: Enzymes. Synonyms: 3-oxo-Δ4-steroid 5β-reductase; 5β-reductase; androstenedione 5β-reductase; cholestenone 5β-reductase; cortis. Enzyme Commission Number: EC 1.3.1.3. CAS No. 9029-8-7. 3-oxo-5-beta-steroid 4-dehydrogenase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1303; Δ4-3-oxosteroid 5β-reductase; EC 1.3.1.3; 9029-08-7; 3-oxo-Δ4-steroid 5β-reductase; 5β-reductase; androstenedione 5β-reductase; cholestenone 5β-reductase; cortisone 5β-reductase; cortisone β-reductase; cortisone Δ4-5β-reductase; steroid 5β-reductase; testosterone 5β-reductase; Δ4-3-ketosteroid 5β-reductase; Δ4-5β-reductase; Δ4-hydrogenase; 4,5β-dihydrocortisone:NADP+ Δ4-oxidoreductase; 3-oxo-5β-steroid:NADP+ Δ4-oxidoreductase. Cat No: EXWM-1303.
Desoxymetasone
Glucocorticoid anti-inflammatory. It is also found as an impurity in Dexamethasone. Group: Biochemicals. Alternative Names: (11 β,16α)-9-Fluoro-11,21-dihydroxy-16-methyl-pregna-1,4-diene-3,20-dione; 17-Deoxydexamethasone; 9-Fluoro-16α-methyl-1-corticosterone; Desoximetasone; Stidex; Topicort; Topicorte; Topisolon. Grades: Purified. CAS No. 382-67-2. Pack Sizes: 100mg, 500mg, 1g, 5g. Molecular Formula: C??H??FO?, Molecular Weight: 376.46. US Biological Life Sciences.
Worldwide
Methylhydrocortisone 21-Hydrogen Succinate
An impurity of Methyl Prednisolone.Prednisolone is a glucocorticoid and an anti-inflammatory drug used to treat central nervous system disorders. Synonyms: BM23AP4A2H; UNII-BM23AP4A2H; Methylhydrocortisone-21-hydrogen succinate; 6|A-Methyl Hydrocortisone 21-Hemisuccinate; 6alpha-Methyl Hydrocortisone 21-Hemisuccinate; Methylhydrocortisone-21-hydrogen hemisuccinate; 4-[2-[(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-6,10,13-trimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethoxy]-4-oxobutanoic acid; Methylprednisolone hydrogen succinate impurity D [EP]; Corticosterone, 17-hydroxy-6alpha-methyl-, 21-(H succinate); 4-((11beta,17-Dihydroxy-6alpha-methyl-3,20-dioxopregn-4-en-21-yl)oxy)-4-oxobutanoic acid; DTXSID60858049; CORTICOSTERONE, 17-HYDROXY-6.ALPHA.-METHYL-, 21-(H SUCCINATE); METHYLPREDNISOLONE HYDROGEN SUCCINATE IMPURITY D [EP IMPURITY]; 4-((11.BETA.,17-DIHYDROXY-6.ALPHA.-METHYL-3,20-DIOXOPREGN-4-EN-21-YL)OXY)-4-OXOBUTANOIC ACID. Grades: > 95%. Molecular formula: C26H36O8. Mole weight: 476.57.
Neuropeptide SF (human)
Neuropeptide SF human augments paraventricular corticotrophin-releasing hormone (CRH) release and increases adrenocorticotropic hormone (ACTH) and corticosterone levels in the plasma. Neuropeptide SF human play a physiologic role in the regulation of such circadian functions as the activity of motor centers and the HPA axis, through the release of CRH [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Neuropeptide NPFF (human). CAS No. 192387-39-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1245.
Osilodrostat
Osilodrostat (LCI699) is a potent, orally active11β-hydroxylase (CYP11B1) inhibitor with an IC 50 value of 35 nM. Osilodrostat is a potent, orally aldosterone synthase (CYP11B2) inhibitor with IC 50 values of 0.7 nM and 160 nM for human aldosterone synthase and rat aldosterone synthase, respectively. Osilodrostat inhibits aldosterone and corticosterone synthesis. Osilodrostat has blood pressure lowering ability. Osilodrostat can be used for research of Cushing syndrome (CS) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LCI699. CAS No. 928134-65-0. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16276.
Osilodrostat phosphate
Osilodrostat (LCI699) phosphate is a potent, orally active11β-hydroxylase (CYP11B1) inhibitor with an IC 50 value of 35 nM. Osilodrostat phosphate is a potent, orally aldosterone synthase (CYP11B2) inhibitor with IC 50 values of 0.7 nM and 160 nM for human aldosterone synthase and rat aldosterone synthase, respectively. Osilodrostat phosphate inhibits aldosterone and corticosterone synthesis. Osilodrostat phosphate has blood pressure lowering ability. Osilodrostat phosphate can be used for research of Cushing syndrome (CS) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LCI699 phosphate. CAS No. 1315449-72-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16276A.
Prednisolone EP Impurity I
Prednisolone EP Impurity I is an impurity of Prednisolone, which is a glucocorticoid and an anti-inflammatory drug used to treat central nervous system disorders. Synonyms: 17-Deoxy Prednisolone; 1,2-Didehydrocorticosterone; 11β,21-Dihydroxypregna-1,4-diene-3,20-dione; 17-Deoxyprednisolone; Δ1-Corticosterone; 17-Dehydroxy Prednisolone; (11β)-11,21-Dihydroxypregna-1,4-diene-3,20-dione; Pregna-1,4-diene-3,20-dione, 11,21-dihydroxy-, (11β)-; Dehydrocorticosterone. Grades: ≥95%. CAS No. 13479-38-4. Molecular formula: C21H28O4. Mole weight: 344.44.
Fludrocortisone Acetate
Fludrocortisone acetate is a synthetic corticosteroid with more mineralocorticoid than glucocorticoid activity. Uses: A mineralocorticoid. Synonyms: 17-dihydroxy-20-dion(11-beta)-pregn-4-ene-21-(acetyloxy)-9-fluoro-11; 20-dione,9-fluoro-11-beta,17,21-trihydroxy-pregn-4-ene-21-acetate; 9-fluoro-11-beta,17,21-trihydroxypregn-4-ene-3,20-dione21-acetate; 9-fluoro-17-hydroxy-corticosteron21-acetate; (11β)-21-(. Grades: > 95%. CAS No. 514-36-3. Molecular formula: C23H31FO6. Mole weight: 422.50.
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