Corticotropin Suppliers USA
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Product | Description | |
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Corticotropin Quick inquiry Where to buy Suppliers range | Corticotropin (ACTH or adrenocorticotropic hormone) is a polypeptide hormone produced and secreted by the pituitary gland. It is an important player in the hypothalamic-pituitary-adrenal axis. Uses: API. CAS No. 12427-33-7. Product ID: 10-101-167. | |
Corticotropin Quick inquiry Where to buy Suppliers range | Corticotropin is a peptide hormone involved in the stress response. Synonyms: Adrendcorticotrophic hormone; ACTH; ACTH (1-39); Acthar; Adrenocorticotrophin; Adrenocorticotropic hormone; Corticotrophin; H.P. acthar gel. CAS No. 9002-60-2. Molecular formula: C207H308N56O58S. Mole weight: 4541.07. | |
Corticotropin-releasing Factor TFA Salt (Human, rat) (Technical Grade) Quick inquiry Where to buy Suppliers range | Corticotropin-releasing Factor TFA Salt (Human, rat) (Technical Grade). Uses: For analytical and research use. Group: Phytochemicals. Alternative Names: Corticorelin Human Trifluoroacetic Acid Salt, Corticorelin Trifluoroacetic Acid Salt,Corticobiss Trifluoroacetic Acid Salt, Human CRF Trifluoroacetic Acid Salt, Corticotropin-releasing Ractor (Rat) Trifluoroacetic Acid Salt, Corticotropin-releasing Factor (Mesocricetus Auratus) Trifluoroacetic Acid Salt, Human ACTH-releasing Factor Trifluoroacetic Acid Salt. Pack Sizes: 1MG. Molecular formula: C208H344N60O63S2.xC2HF3O2. Mole weight: 4757.45. Catalog: APS007067. SMILES: ['Ser'] ['Glu'] ['Glu'] ['Pro'] ['Pro'] ['Ile'] ['Ser'] ['Leu'] ['Asp'] ['Leu'] ['Thr'] ['Phe'] ['His'] ['Leu'] ['Leu'] ['Arg'] ['Glu'] ['Val'] ['Leu'] ['Glu'] ['Met'] ['Ala'] ['Arg'] ['Ala'] ['Glu'] ['Gln'] ['Leu'] ['Ala'] ['Gln'] ['Gln'] ['Ala'] ['His'] ['Ser'] ['Asn'] ['Arg'] ['Lys'] ['Leu'] ['Met'] ['Glu'] ['Ile'] ['Ile']N. OC (=O) C (F) (F) F. Format: Neat. Shipping: Room Temperature. | |
a1-17-Corticotropin Quick inquiry Where to buy Suppliers range | a1-17-Corticotropin. Group: Heterocyclic Organic Compound. Alternative Names: H-SER-TYR-SER-MET-GLU-HIS-PHE-ARG-TRP-GLY-LYS-PRO-VAL-GLY-LYS-LYS-ARG-OH;ACTH (1-17);ACTH (1-17), HUMAN;ADRENOCORTICOTROPIC HORMONE FRAGMENT 1-17;ADRENOCORTICOTROPIC HORMONE (1-17), HUMAN;ADRENOCORTICOTROPIC HORMONE (1-27);ADRENOCORTICOTROPIC HORMONE HUM. Grades: 96%. CAS No. 7266-47-9. Product ID: ACM7266479. Molecular formula: C95H145 N29 O23 S. Mole weight: 2093.41. IUPAC Name: Adrenocorticotropic Hormone Fragment 1-17 human, rat. | |
a1-24-Corticotropin,2-L-phenylalanine-4-L-norleucine-(9ci) Quick inquiry Where to buy Suppliers range | a1-24-Corticotropin,2-L-phenylalanine-4-L-norleucine-(9ci). Group: Heterocyclic Organic Compound. Alternative Names: H-SER-PHE-SER-NLE-GLU-HIS-PHE-ARG-TRP-GLY-LYS-PRO-VAL-GLY-LYS-LYS-ARG-ARG-PRO-VAL-LYS-VAL-TYR-PRO-OH;SFS-NLE-EHFRWGKPVGKKRRPVKVYP;SER-PHE-SER-NLE-GLU-HIS-PHE-ARG-TRP-GLY-LYS-PRO-VAL-GLY-LYS-LYS-ARG-ARG-PRO-VAL-LYS-VAL-TYR-PRO;[PHE2, NLE4]-ACTH (1-24);[PH. Grades: 96%. CAS No. 97773-00-7. Molecular formula: C137H212N40O30. Mole weight: 2899.4. IUPAC Name: [Phe2, Nle4]-ACTH (1-24),SFS-Nle-EHFRWGKPVGKKRRPVKVYP. Exact Mass: 2897.63000. SMILES: CCCCC (C (=O)NC (CCC (=O)O)C (=O)NC (CC1=CNC=N1)C (=O)NC (CC2=CC=CC=C2)C (=O)NC (CCCNC (=N)N)C (=O)NC (CC3=CNC4=CC=CC=C43)C (=O)NCC (=O)NC (CCCCN)C (=O)N5CCCC5C (=O)NC (C (C)C)C (=O)NCC (=O)NC (CCCCN)C (=O)NC (CCCCN)C (=O)NC (CCCNC (=N)N)C (=O)NC (CCCNC (=N)N)C (=O)N6CCCC6C (=O)NC (C (C)C)C (=O)NC (CCCCN)C (=O)NC (C (C)C)C (=O)NC (CC7=CC=C (C=C7)O)C (=O)N8CCCC8C (=O)O)NC (=O)C (CO)NC (=O)C (CC9=CC=CC=C9)NC (=O)C (CO)N. InChIKey: OIPMQAUTERWDFC-IXBZEBJWSA-N. | |
1,3-Dichloro-5-isocyanatobenzene Quick inquiry Where to buy Suppliers range | 1,3-Dichloro-5-isocyanatobenzene is a reagent used in the synthesis of carbamate and aryl ether substituted pyrazinones as corticotropin releasing factor-1 receptor antagonists as well as the synthesis of novel triazolor pyridine derivatives. Group: Biochemicals. Grades: Highly Purified. CAS No. 34893-92-0. Pack Sizes: 5g, 10g. Molecular Formula: C7H3Cl2NO. US Biological Life Sciences. | Worldwide |
2,4-Dichloro-6-methyltriazine Quick inquiry Where to buy Suppliers range | 2,4-Dichloro-6-methyltriazine is a reagent used to prepare triazinyl-amines as inhibitors of HIV-1 reverse transcriptase. It is also used in the synthesis of anilinotriazine corticotropin releasing hormone antagonists. Group: Biochemicals. Grades: Highly Purified. CAS No. 1973-4-2. Pack Sizes: 500mg, 1g. Molecular Formula: C4H3Cl2N3, Molecular Weight: 163.99. US Biological Life Sciences. | Worldwide |
2-Chloro-5-nitroquinoline Quick inquiry Where to buy Suppliers range | 2-Chloro-5-nitroquinoline is used in the synthesis of potent, orally active corticotropin-releasing factor-1 receptor antagonists. Group: Biochemicals. Alternative Names: 5-Nitro-2-chloroquinoline; NSC 261562. Grades: Highly Purified. CAS No. 13067-94-2. Pack Sizes: 500mg. US Biological Life Sciences. | Worldwide |
2-Hydroxy-4-methylpyridine-d3 Quick inquiry Where to buy Suppliers range | 2-Hydroxy-4-methylpyridine-d3 is the isotope labelled analog of 2-Hydroxy-4-methylpyridine (H949890); an intermediate used to prepare oxobenzopyrancarboxyl ate derivatives as inhibitors of serine proteases and human leukocyte elastase. It is also used in the synthesis of (indanylamino) (pyridinyloxy) pyrazines and analogs as corticotropin releasing factor type-1 receptor antagonists. Group: Biochemicals. Grades: Highly Purified. CAS No. 1185316-03-3. Pack Sizes: 5mg, 10mg. Molecular Formula: C6H4D3NO, Molecular Weight: 112.14. US Biological Life Sciences. | Worldwide |
2-Hydroxy-4-methylpyridine-d6 Quick inquiry Where to buy Suppliers range | 2-Hydroxy-4-methylpyridine-d6 is the isotope labelled analog of 2-Hydroxy-4-methylpyridine (H949890); an intermediate used to prepare oxobenzopyrancarboxyl ate derivatives as inhibitors of serine proteases and human leukocyte elastase. It is also used in the synthesis of (indanylamino) (pyridinyloxy) pyrazines and analogs as corticotropin releasing factor type-1 receptor antagonists. Group: Biochemicals. Grades: Highly Purified. CAS No. 916979-13-0. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C6HD6NO, Molecular Weight: 115.16. US Biological Life Sciences. | Worldwide |
3-[6-(Dimethylamino)-4-methyl-3-pyridinyl]-2,5-dimethyl-N,N-dipropylpyrazolo[1,5-a]pyrimidin-7-amine Quick inquiry Where to buy Suppliers range | 3-[6-(Dimethylamino)-4-methyl-3-pyridinyl]-2,5-dimethyl-N,N-dipropylpyrazolo[1,5-a]pyrimidin-7-amine, is a potent and Orally active Corticotropin-Releasing factor 1 receptor antagonists, which is hown to reduce negative emotional symptoms of acute and protracted alcohol withdrawal, and thus used for the treatment of alcoholism. Group: Biochemicals. Grades: Highly Purified. CAS No. 195055-03-9. Pack Sizes: 1mg. Molecular Formula: C22H32N6, Molecular Weight: 380.53. US Biological Life Sciences. | Worldwide |
ACTH (1-10), human Quick inquiry Where to buy Suppliers range | Adrenocorticotropic hormone (ACTH) (1-10) is an N-terminal peptide fragment of ACTH, a peptide hormone produced by the anterior pituitary gland that is involved in the biological stress response. Synonyms: H-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-OH; L-seryl-L-tyrosyl-L-seryl-L-methionyl-L-alpha-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophyl-glycine; ACTH (1-10) (human, mouse, rat, porcine, bovine, ovine); Adrenocorticotropic Hormone (1-10); Corticotropin (1-10); Adrenocorticotropic Hormone (ACTH) (1-10), human. Grades: ≥97% by HPLC. CAS No. 2791-5-1. Molecular formula: C59H78N16O16S. Mole weight: 1299.41. | |
ACTH 11-24 Quick inquiry Where to buy Suppliers range | ACTH(11-24) is a fragment of the adrenocorticotropic hormone (ACTH) and an antagonist of the adrenocorticotropic hormone (ACTH) receptor that induces cortisol release. Synonyms: Adrenocorticotropic Hormone (11-24); H-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-OH; L-lysyl-L-prolyl-L-valyl-glycyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-prolyl-L-valyl-L-lysyl-L-valyl-L-tyrosyl-L-proline; a11-24-Corticotropin; alpha11-24-Corticotropin; Adrenocorticotropic hormone fragment 11-24, human. Grades: ≥90%. CAS No. 4237-93-8. Molecular formula: C77H134N24O16. Mole weight: 1652.04. | |
ACTH 1-13 Quick inquiry Where to buy Suppliers range | ACTH (1-13) is a 13-aa peptide with cytoprotective effects in the model of ethanol induced gastric lesions in rats. Uses: Hormones. Synonyms: Adrenocorticotropic Hormone (1-13); H-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-OH; L-seryl-L-tyrosyl-L-seryl-L-methionyl-L-alpha-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophyl-glycyl-L-lysyl-L-prolyl-L-valine; Tridecactide; Des-acetyl MSH; DE-alpha-Msh; (Des-acetyl)-alpha-MSH; alpha 1-13-Corticotropin, human; Desacetyl alpha-melanocyte-stimulating hormone; a1-13-Corticotropin. Grades: ≥95%. CAS No. 22006-64-0. Molecular formula: C75H106N20O19S. Mole weight: 1623.83. | |
ACTH 1-14 Quick inquiry Where to buy Suppliers range | ACTH(1-14) is a fragment of the adrenocorticotropic hormone that regulates the production of cortisol and androgens. Synonyms: Adrenocorticotropic Hormone Fragment 1-14; Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly; alpha1-14-Corticotropin; L-seryl-L-tyrosyl-L-seryl-L-methionyl-L-alpha-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophyl-glycyl-L-lysyl-L-prolyl-L-valyl-glycine; Acth(1-14) huamn. Grades: ≥90%. CAS No. 25696-21-3. Molecular formula: C77H109N21O20S. Mole weight: 1680.88. | |
ACTH (1-14) acetate Quick inquiry Where to buy Suppliers range | ACTH (1-14) acetate is a fragment of the adrenocorticotropic hormone that regulates the production of cortisol and androgens. Synonyms: Adrenocorticotropic Hormone Fragment 1-14 acetate; H-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-OH.CH3CO2H; L-seryl-L-tyrosyl-L-seryl-L-methionyl-L-alpha-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophyl-glycyl-L-lysyl-L-prolyl-L-valyl-glycine acetic acid; α1-14-Corticotropin acetate; α-Melanotropin (Rana catesbeiana) acetate; α-MSH (chicken) acetate; ACTH 1-14 acetate; α1-14-ACTH acetate. Grades: ≥95%. Molecular formula: C79H113N21O22S. Mole weight: 1740.96. | |
ACTH 1-17 Quick inquiry Where to buy Suppliers range | ACTH (1-17) is a peptide fragment of ACTH, a tropic hormone produced by the anterior pituitary. Synonyms: Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg; Alpha1-17-ACTH; a1-17-Corticotropin; L-seryl-L-tyrosyl-L-seryl-L-methionyl-L-alpha-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophyl-glycyl-L-lysyl-L-prolyl-L-valyl-glycyl-L-lysyl-L-lysyl-L-arginine; 1-Ala-17-Lys-ACTH 4-amino-n-butylamide; 1-beta-Alanine-17-(L-2,6-diamino-N-(4-aminobutyl)hexanamide)-alpha1-17-corticotrophin; alsactide; Synchrodyn; Adrenocorticotropic Hormone Fragment 1-17 human, rat. Grades: 98%. CAS No. 7266-47-9. Molecular formula: C95H145N29O23S. Mole weight: 2093.41. | |
ACTH (1-39) (Human) Quick inquiry Where to buy Suppliers range | Potent endogenous melanocortin receptor 2 (MC2) agonist (EC50 = 57 pM). Component of the hypothalamic-pituitary-adrenal (HPA) axis that stimulates glucocorticoid production and release from the adrenal cortex. Induces insulin resistance, promotes a proinflammatory profile and stimulates UCP-1 in adipocytes in vitro. Group: Biochemicals. Alternative Names: Adrenocorticotropic hormone (1-39); Adrenocorticotropin; Corticotropin. Grades: Highly Purified. CAS No. 12279-41-3. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
ACTH (1-39), Porcine Quick inquiry Where to buy Suppliers range | ACTH (1-39) is a potent agonist of melanocortin receptor 2 (MC2R) with an EC50 value of 57 pM in HeLa cells expressing the mouse receptor. Synonyms: Adrenocorticotropic Hormone from porcine pituitary; Adrenocorticotropic Hormone Fragment 1-39; Corticotropin A. Grades: 95%. CAS No. 9061-27-2. Molecular formula: C210H314N56O57S. Mole weight: 4567.15. | |
ACTH (2-24) (human, bovine, rat) Quick inquiry Where to buy Suppliers range | ACTH (2-24) (human, bovine, rat) is an impurity of tetracosactide, a synthetic peptide analog of the human adrenocorticotropic hormone that stimulates cortisol production. Synonyms: Tetracosactide (2-24); H-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-OH; Corticotropin (2-24); L-tyrosyl-L-seryl-L-methionyl-L-alpha-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophyl-glycyl-L-lysyl-L-prolyl-L-valyl-glycyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-prolyl-L-valyl-L-lysyl-L-valyl-L-tyrosyl-L-proline. Grades: ≥95%. CAS No. 67654-32-4. Molecular formula: C133H205N39O29S. Mole weight: 2846.36. | |
ACTH (4-10) Quick inquiry Where to buy Suppliers range | ACTH (4-10) is a fragment of Adrenocorticotropic Hormone (ACTH), a melanocortin 4 (MC4R) receptor agonist. Synonyms: α-MSH (4-10); ACTH (4-10), human; corticotropin (4-10); H-Met-Glu-His-Phe-Arg-Trp-Gly-OH; Met-glu-his-phe-arg-trp-gly. Grades: >95%. CAS No. 4037-1-8. Molecular formula: C44H59N13O10S. Mole weight: 962.08. | |
ACTH (4-10) (human, mouse, rat, porcine, bovine, ovine) trifluoroacetate salt Quick inquiry Where to buy Suppliers range | Adrenocorticotropic hormone (ACTH) (4-10) is an endogenous peptide fragment of ACTH, a peptide hormone produced by the anterior pituitary gland that is involved in the biological stress response. Synonyms: Adrenocorticotropic hormone (4-10); Corticotropin (4-10); H-Met-Glu-His-Phe-Arg-Trp-Gly-OH. Grades: ≥95%. Molecular formula: C44H59N13O10S·xCF3COOH. Mole weight: 962.09. | |
ACTH (6-24) (human, mouse, rat, porcine, bovine, ovine) trifluoroacetate salt Quick inquiry Where to buy Suppliers range | ACTH (6-24) is a peptide fragment of adrenocorticotropic hormone, a peptide hormone found in the brain that is involved in the biological stress response. Synonyms: HFRWGKPVGKKRRPVKVYP; Corticotropin-(6-24)-peptide. Grades: ≥95%. CAS No. 33512-65-1. Molecular formula: C111H175N35O21·xCF3COOH. Mole weight: 2335.8. | |
Adrenocorticotropic Hormone (ACTH) (18-39), human Quick inquiry Where to buy Suppliers range | Adrenocorticotropic Hormone (ACTH) (18-39), human is a corticotropinlike intermediate lobe peptide, which is produced in the melanotrophs of the intermediate lobe of the pituitary. Uses: Peptide Inhibitors. CAS No. 53917-42-3. Product ID: R1166. | |
Adrenocorticotropic Hormone (ACTH) (18-39), human TFA Quick inquiry Where to buy Suppliers range | Adrenocorticotropic Hormone (ACTH) (18-39), human TFA is a corticotropinlike intermediate lobe peptide, which is is produced in the melanotrophs of the intermediate lobe of the pituitary. Uses: Peptide Inhibitors. CAS No. 73724-75-1. Product ID: R1167. | |
Adrenocorticotropic Hormone Fragment 7-38 human Quick inquiry Where to buy Suppliers range | Synonyms: Corticostatin; (7-28)-Corticotropin; Acth(7-38); CIP peptide. CAS No. 68563-24-6. Molecular formula: C167H257N47O46. Mole weight: 3659.11. | |
α-helical CRF 9-41 Quick inquiry Where to buy Suppliers range | α-helical CRF 9-41 has been found to be a corticotropin-releasing factor receptor antagonist. Synonyms: Corticotropin-releasing factor (human), 1-de-L-serine-2-de-L-glutamicacid-3-de-L-glutamicacid-4-de-L-proline-5-de-L-proline-6-de-L-isoleucine-7-de-L-serine-8-de-L-leucine-18-L-methionine-23-L-lysine-27-L-glutamic acid-29-L-glutamicacid-32-L-alanine-33-L-leucine-36-L-leucine-38-L-leucine-40-L-glutamicacid-41-L-alaninamide-; CHEMBL526149. Grades: ≥95% by HPLC. CAS No. 90880-23-2. Molecular formula: C166H274N46O53S2. Mole weight: 3827.00. | |
Antalarmin hydrochloride Quick inquiry Where to buy Suppliers range | Antalarmin hydrochloride is the hydrochloride salt of antalarmin, which is a selective nonpeptide antagonist of the corticotropin-releasing hormone (CRH) receptor 1 with Ki value of 1 nM. It suppresses CRF-induced ACTH secretion and blocks CRF- and novelty-induced anxiety-like behavior in animal models of anxiety. It also can reduce cardiovascular, endocrinological and behavioral responses to stressful stimuli through its antagonism of central CRH signaling. It produces anti-inflammatory effects in arthritis models by reducing dose escalation in cocaine-addicted rats and suppresses stress-induced gastric ulceration related to irritable bowel syndrome. Synonyms: N-Butyl-N-ethyl-2,5,6-trimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, Monohydrochloride; N-Butyl-N-ethyl-2,5,6-trimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, Hydrochloride. Grades: ≥99% by HPLC. CAS No. 220953-69-5. Molecular formula: C24H35N4Cl. Mole weight: 415.01. | |
Antisauvagine-30 Quick inquiry Where to buy Suppliers range | Antisauvagine-30 is a selective, competitive and potent corticotropin-releasing factor CRF2 receptor antagonist with Kd values of 153.6 and 1.4 nM for binding to rat CRF1 and mouse CRF2β receptors respectively. It prevents stress-enhanced fear conditioning and MEK 1/2-dependent activation of ERK1/2 in mice in vivo. It inhibits sauvagine-stimulated cAMP accumulation in HEK-mCRF2β cells. Synonyms: (D-Phe11,His12)-Sauvagine (11-40); H-D-Phe-His-Leu-Leu-Arg-Lys-Met-Ile-Glu-Ile-Glu-Lys-Gln-Glu-Lys-Glu-Lys-Gln-Gln-Ala-Ala-Asn-Asn-Arg-Leu-Leu-Leu-Asp-Thr-Ile-OH; D-phenylalanyl-L-histidyl-L-leucyl-L-leucyl-L-arginyl-L-lysyl-L-methionyl-L-isoleucyl-L-alpha-glutamyl-L-isoleucyl-L-alpha-glutamyl-L-lysyl-L-glutaminyl-L-alpha-glutamyl-L-lysyl-L-alpha-glutamyl-L-lysyl-L-glutaminyl-L-glutaminyl-L-alanyl-L-alanyl-L-asparagyl-L-asparagyl-L-arginyl-L-leucyl-L-leucyl-L-leucyl-L-alpha-aspartyl-L-threonyl-L-isoleucine; 11-D-Phenylalanine-12-L-histidine-11-40-sauvagine (11-40). Grades: ≥95%. CAS No. 220673-95-0. Molecular formula: C161H274N48O46S. Mole weight: 3650.29. | |
Astressin Quick inquiry Where to buy Suppliers range | Astressin is a potent corticotropin releasing factor (CRF) antagonist. Uses: Peptide Inhibitors. CAS No. 170809-51-5. Product ID: R1219. | |
Astressin Quick inquiry Where to buy Suppliers range | Astressin is a novel potent corticotropin releasing factor (CRF) antagonist. Astressin may be a useful tool to explore functional CRF-dependent physiological pathways in specific brain nuclei. Uses: Neuroprotective agents. Synonyms: (D-Phe12,Nle21·38,Glu30,Lys33)-CRF (12-41) (human, rat); H-D-Phe-His-Leu-Leu-Arg-Glu-Val-Leu-Glu-Nle-Ala-Arg-Ala-Glu-Gln-Leu-Ala-Gln-Glu(1)-Ala-His-Lys(1)-Asn-Arg-Lys-Leu-Nle-Glu-Ile-Ile-NH2. Grades: ≥95%. CAS No. 170809-51-5. Molecular formula: C161H269N49O42. Mole weight: 3563.16. | |
Astressin 2B Quick inquiry Where to buy Suppliers range | Astressin 2B is a selective and potent corticotropin-releasing factor receptor 2 (CRF2) antagonist with IC50 values of > 500 nM and 1.3 for CRF1 and CRF2 respectively. It antagonizes CRF2-mediated inhibition of gastric emptying. Synonyms: Cyclo(31-34)[D-Phe11, His12, C(α)MeLeu13, 39, Nle17, Glu31, Lys34]Ac-Svg(8-40). Grades: >98%. CAS No. 681260-70-8. Molecular formula: C183H307N49O53. Mole weight: 4041.69. | |
Astressin 2B Quick inquiry Where to buy Suppliers range | Selective and potent antagonist of corticotropin-releasing factor receptor 2 (CRF2) (IC50 values are 1.3 and > 500 nM for CRF2 and CRF1 respectively) that antagonizes CRF2-mediated inhibition of gastric emptying. Uses: Peptide Inhibitors. CAS No. 681260-70-8. Product ID: R1100. | |
Clip Quick inquiry Where to buy Suppliers range | Clip. Group: Heterocyclic Organic Compound. Alternative Names: corticotropin-likeintermediatelobepeptide;H-ARG-PRO-VAL-LYS-VAL-TYR-PRO-ASN-GLY-ALA-GLU-ASP-GLU-SER-ALA-GLU-ALA-PHE-PRO-LEU-GLU-PHE-OH;CLIP (HUMAN);CLIP;CORTICOTROPIN A;CORTICOTROPIN-LIKE INTERMEDIATE LOBE PEPTIDE HUMAN;CORTICOTROPIN-LIKE INTERMEDIATE PE. Grades: 96%. CAS No. 53917-42-3. Product ID: ACM53917423. Molecular formula: C112H165N27O36. Mole weight: 2465.67. IUPAC Name: Adrenocorticotropic Hormone. Appearance: White powder. Density: 1.49g/cm³. | |
Corticostatin 1 Quick inquiry Where to buy Suppliers range | Corticostatin 1 is from Oryctolagus cuniculus. It has microbicidal activity and inhibits corticotropin (ACTH) stimulated corticosterone production. Synonyms: Antiadrenocorticotropin peptide I. | |
Corticostatin-6 Quick inquiry Where to buy Suppliers range | Corticostatin-6 is from Oryctolagus cuniculus. It has microbicidal activity and inhibits corticotropin (ACTH) stimulated corticosterone production. | |
Corticostatin-related peptide LCRP Quick inquiry Where to buy Suppliers range | Corticostatin-related peptide LCRP is isolated from Petromyzon marinus. It may inhibit corticotropin (ACTH) stimulated steroidogenesis and the microbial actions of the corticostatins. | |
Cortisol (HRP) Quick inquiry Where to buy Suppliers range | Cortisol is the most potent glucocorticoid produced by the human adrenal. It is synthesized from cholesterol and its production is stimulated by pituitary adrenocorticotropic hormone (ACTH) which is regulated by corticotropin releasing factor (CRF). ACTH and CRF secretions are inhibited by high cortisol levels in a negative feedback loop. In plasma a majority of cortisol is bound with high affinity to corticosteroid binding globulin (CBG or transcotin). Cortisol acts through specific intracellular receptors and affects numerous physiologic systems including immune function, glucose counter regulation, vascular tone, and bone metabolism. Group: Biochemicals. Grades: Purified. Pack Sizes: 500ul. US Biological Life Sciences. | Worldwide |
CP-154526 Hydrochloride Quick inquiry Where to buy Suppliers range | A selective, non-peptide antagonist of corticotropin releasing factor receptors (CRF1). It blocks CRF-induced adenylate cyclase activation and attenuates activation of the HPA axis by CRF. It displayed anxiolytic-like activity in the rat elevated plus-maze test; brain penetrant. Group: Biochemicals. Alternative Names: N-Butyl-N-ethyl-2,5-dimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine Hydrochloride. Grades: Highly Purified. CAS No. 257639-98-8. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
CRF (6-33) Quick inquiry Where to buy Suppliers range | A peptide inhibitor of corticotropin-releasing factor binding protein (CRFBP) that displaces CRF from CRFBP, and suppresses body weight gain and increases motor activity in obese rats in vivo. Uses: Peptide Inhibitors. CAS No. 120066-38-8. Product ID: R1023. | |
CRF (6-33) Quick inquiry Where to buy Suppliers range | CRF (6-33) has been found to be a CRFBP inhibitor peptide and could probably suppress body weight gain. Synonyms: Corticotropin-Releasing Factor (6-33). Grades: >98%. CAS No. 120066-38-8. Molecular formula: C141H231N41O43S. Mole weight: 3220.68. | |
CRF (6-33) acetate Quick inquiry Where to buy Suppliers range | CRF (6-33) acetate has been found to be a corticotropin-releasing factor binding protein (CRFBP) inhibitor peptide and could probably suppress body weight gain. Synonyms: H-Ile-Ser-Leu-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Glu-Val-Leu-Glu-Met-Ala-Arg-Ala-Glu-Gln-Leu-Ala-Gln-Gln-Ala-His-Ser-OH.CH3CO2H; L-isoleucyl-L-seryl-L-leucyl-L-alpha-aspartyl-L-leucyl-L-threonyl-L-phenylalanyl-L-histidyl-L-leucyl-L-leucyl-L-arginyl-L-alpha-glutamyl-L-valyl-L-leucyl-L-alpha-glutamyl-L-methionyl-L-alanyl-L-arginyl-L-alanyl-L-alpha-glutamyl-L-glutaminyl-L-leucyl-L-alanyl-L-glutaminyl-L-glutaminyl-L-alanyl-L-histidyl-L-serine acetate; 6-33-Human ACTH-releasing factor acetate; Rat corticotropin-releasing factor(6-33) acetate. Grades: ≥95%. Molecular formula: C143H235N41O45S. Mole weight: 3280.76. | |
CRF, bovine Quick inquiry Where to buy Suppliers range | CRF, bovine is an effective agonist of CRF (Corticotropin-releasing factor) receptor. Synonyms: Corticotropin Releasing Factor bovine; H-Ser-Gln-Glu-D-Pro-D-Pro-Ile-Ser-Leu-Asp-Leu-aThr-Phe-His-Leu-Leu-Arg-Glu-Val-Leu-Glu-DL-Met-Thr-Lys-D-Ala-D-Asp-D-Gln-D-Leu-D-Ala-D-Gln-D-Gln-D-Ala-D-His-D-Asn-D-Asn-D-Arg-D-Lys-D-Leu-D-Leu-D-Asp-aIle-D-Ala-NH2; L-seryl-L-glutaminyl-L-alpha-glutamyl-D-prolyl-D-prolyl-L-isoleucyl-L-seryl-L-leucyl-L-alpha-aspartyl-L-leucyl-L-allothreonyl-L-phenylalanyl-L-histidyl-L-leucyl-L-leucyl-L-arginyl-L-alpha-glutamyl-L-valyl-L-leucyl-L-alpha-glutamyl-DL-methionyl-L-threonyl-L-lysyl-D-alanyl-D-alpha-aspartyl-D-glutaminyl-D-leucyl-D-alanyl-D-glutaminyl-D-glutaminyl-D-alanyl-D-histidyl-D-asparagyl-D-asparagyl-D-arginyl-D-lysyl-D-leucyl-D-leucyl-D-alpha-aspartyl-L-alloisoleucyl-D-alaninamide. Grades: 95%. CAS No. 92307-52-3. Molecular formula: C206H340N60O63S. Mole weight: 4697.33. | |
CRF (human, rat) Quick inquiry Where to buy Suppliers range | CRF (human, rat) has been found to be an endogenous peptide agonist and could stimulate the release of ACTH from the anterior pituitary. Synonyms: Corticotropin-releasing factor (human); Corticotropin-releasing factor (sheep), 2-L-glutamic acid-22-L-alanine-23-L-arginine-25-L-glutamic acid-38-L-methionine-39-L-glutamic acid-41-L-isoleucinamide-; L-Isoleucinamide, L-seryl-L-α-glutamyl-L-α-glutamyl-L-prolyl-L-prolyl-L-isoleucyl-L-seryl-L-leucyl-L-α-aspartyl-L-leucyl-L-threonyl-L-phenylalanyl-L-histidyl-L-leucyl-L-leucyl-L-arginyl-L-α-glutamyl-L-valyl-L-leucyl-L-α-glutamyl-L-methionyl-L-alanyl-L-arginyl-L-alanyl-L-α-glutamyl-L-glutaminyl-L-leucyl-L-alanyl-L-glutaminyl-L-glutaminyl-L-alanyl-L-histidyl-L-seryl-L-asparaginyl-L-arginyl-L-lysyl-L-leucyl-L-methionyl-L-α-glutamyl-L-isoleucyl-; Corticobiss; Corticorelin; Corticorelin human; Corticotropin-releasing factor (horse); Corticotropin-releasing factor (Mesocricetus auratus); Corticotropin-releasing factor (rat); Human ACTH-releasing factor; Human corticorelin; Human corticotropin-releasing factor; Human corticotropin-releasing hormone; Human corticotropin-releasing hormone-41; Human CRF; Human CRF(1-41); Human/rat CRF; MCI 028; Rat ACTH-releasing hormone; Rat corticotropin-releasing factor; Rat corticotropin-releasing factor-41; Rat CRF; Rat CRF(1-41); Rat CRF-41; Rat hypothalamic CRF; Rat/human corticotropin-releasing factor; Rat/human CRF; rCRF-41; H-Ser-Glu-Glu-Pro-Pro-Ile-Ser-Leu-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Glu-Val-Leu-Glu-Met-Ala-Arg-Ala-Glu-Gln-Leu-Ala-Gln-Gln-Ala-His-Ser-Asn-Arg-Lys-Leu-Met-Glu-Ile-Ile-NH2. Grades: ≥95% by HPLC. CAS No. 86784-80-7. Molecular formula: C208H344N60O63S2. Mole weight: 4758.00. | |
CRF(human,rat) Quick inquiry Where to buy Suppliers range | Corticotropin-releasing factor (CRF) (human) stimulates the synthesis and secretion of adrenocorticotropin in the anterior pituitary. Uses: API. CAS No. 86784-80-7. Product ID: 10-101-294. | |
CRF (human, rat) Acetate Quick inquiry Where to buy Suppliers range | Corticotropin-releasing hormone (CRH) also known as corticotropin-releasing factor (CRF) or corticoliberin is a 41-amino acid peptide derived from a 196-amino acid preprohormone. CRH belongs to corticotropin-releasing factor family and is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. Uses: API. CAS No. 86784-80-7. Product ID: 10-101-75. | |
CRF (ovine) Trifluoroacetate Quick inquiry Where to buy Suppliers range | Corticorelin ovine triflutate is a 41 amino-acid peptide similar to human corticotropin-releasing hormone (CRH). It is a potent stimulator of adrenocorticotropic hormone (ACTH). Uses: API. CAS No. 79804-71-0. Product ID: 10-101-76. | |
(D-Phe12,Nle21.38,α-Me-Leu37)-CRF (12-41) (human, rat) Quick inquiry Where to buy Suppliers range | (D-Phe12,Nle21.38,α-Me-Leu37)-CRF (12-41) (human, rat) is a potent and long-acting CRF antagonist. Synonyms: H-D-Phe-His-Leu-Leu-Arg-Glu-Val-Leu-Glu-Nle-Ala-Arg-Ala-Glu-Gln-Leu-Ala-Gln-Gln-Ala-His-Ser-Asn-Arg-Lys-α-Me-Leu-Nle-Glu-Ile-Ile-NH2; D-Phenylalanyl-L-histidyl-L-leucyl-L-leucyl-L-arginyl-L-α-glutamyl-L-valyl-L-leucyl-L-α-glutamyl-L-norleucyl-L-alanyl-L-arginyl-L-alanyl-L-α-glutamyl-L-glutaminyl-L-leucyl-L-alanyl-L-glutaminyl-L-glutaminyl-L-alanyl-L-histidyl-L-seryl-L-asparaginyl-L-arginyl-L-lysyl-2-methyl-L-leucyl-L-norleucyl-L-α-glutamyl-L-isoleucyl-L-isoleucinamide; 12-41-Corticotropin-releasing factor (human), 12-D-phenylalanine-21-L-norleucine-37-(2-methyl-L-leucine)-38-L-norleucine-. Grades: ≥95%. CAS No. 150646-45-0. Molecular formula: C159H267N49O43. Mole weight: 3553.17. | |
(D-Ser1)-ACTH (1-24) (human, bovine, rat) Quick inquiry Where to buy Suppliers range | (D-Ser1)-ACTH (1-24) (human, bovine, rat) is a seminal peptide hormone within the scientific community, plays the role of an adrenocorticotropic hormone (ACTH) receptor agonist. Its diverse applications in both research and therapy encompass disorders characterized by adrenal insufficiency, the formidable Cushing's syndrome and an array of conditions impacting the adrenal cortex. Synonyms: (D-Ser1)-Tetracosactide; H-D-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-OH; α1-24-Corticotropin, 1-D-serine-; Proline, D-seryl-L-tyrosyl-L-seryl-L-methionyl-L-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophylglycyl-L-lysyl-L-prolyl-L-valylglycyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-prolyl-L-valyl-L-lysyl-L-valyl-L-tyrosyl-; D-Ser1-Met4-tetracosapeptide; Ba 38522. Grades: ≥95%. CAS No. 18067-65-7. Molecular formula: C136H210N40O31S. Mole weight: 2933.44. | |
Emicerfont Quick inquiry Where to buy Suppliers range | Emicerfont is a Corticotropin releasing factor receptor 1 antagonist. It can block the CRF1 receptor and so reduce ACTH release. It has been investigated for the treatment of irritable bowel syndrome (IBS) and alcoholism. In Feb 2008, GlaxoSmithKline completed enrolment in its Phase-II trial for Irritable bowel syndrome in the US and Canada. Uses: Irritable bowel syndrome (ibs) and alcoholism. Synonyms: GW876008; 1-{1-[1-(4-Methoxy-2-methylphenyl)-6-methyl-2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-4-yl]-1H-pyrazol-3-yl}imidazolidin-2-one; GW876008X; 2-Imidazolidinone, 1-[1-[2,3-dihydro-1-(4-methoxy-2-methylphenyl)-6-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl]-1H-pyrazol-3-yl]-. Grades: 98%. CAS No. 786701-13-1. Molecular formula: C22H24N6O2. Mole weight: 404.47. | |
JNJ-19567470 Quick inquiry Where to buy Suppliers range | JNJ-19567470 is a selective Corticotropin releasing factor (CRF) receptor antagonist. It is a novel target for developing anti-panic drugs. JNJ-19567470 is as effective as benzodiazepines in treatment of a panic attack which prevents sodium lactate-induced acute panic-like responses. In Oct 2009, preclinical development in Anxiety disorders was ongoing in Japan. Uses: Anxiety disorders. Synonyms: JNJ-19567470; JNJ19567470; JNJ 19567470; TAI-041; TAI 041; TAI041; R-317573;1-(7-(4-bromo-2,6-dimethylphenyl)-2,5-dimethyl-7H-pyrrolo(2,3-d)pyrimidin-4-yl)-4-Piperidinemethanol. Grades: 98%. CAS No. 724471-26-5. Molecular formula: C22H27BrN4O. Mole weight: 443.38. | |
N-acetyl semax Quick inquiry Where to buy Suppliers range | N-acetyl semax is a modified fragment of the corticotropin hormone. Synonyms: L-Methionyl-L-α-glutamylhistidyl-L-phenylalanyl-L-prolylglycyl-L-proline, (Pro8,Gly9,Pro10)ACTH-(4-10). Grades: 98%. Molecular formula: C37H51N9O10S. Mole weight: 813.92. | |
NBI-27914 Quick inquiry Where to buy Suppliers range | NBI-27914 is antagonist of the CRF1 and CRF2 recepetors (Corticotropin-releasing factor). Synonyms: 5-chloro-4-N-(cyclopropylmethyl)-2-methyl-4-N-propyl-6-N-(2,4,6-trichlorophenyl)pyrimidine-4,6-diamine; 2-methyl-4-(N-propyl-N-cycloproanemethylamino)-5-chloro-6-(2,4,6-trichloranilino)pyrimidine; NBI 27914; NBI27914. Grades: >99 %. CAS No. 184241-44-9. Molecular formula: C18H20Cl4N4. Mole weight: 434.186. | |
NBI 27914 hydrochloride Quick inquiry Where to buy Suppliers range | NBI 27914 hydrochloride is a corticotropin-releasing factor1 receptor antagonist. It can block behavioral seizures in vivo. Synonyms: NBI 27914 hydrochloride; NBI27914 hydrochloride; NBI-27914 hydrochloride; 5-Chloro-N-(cyclopropylmethyl)-2-methyl-N-propyl-N'-(2,4,6-trichlorophenyl)-4,6-pyrimidinediamine hydrochloride. Grades: ≥99% by HPLC. CAS No. 1215766-76-9. Molecular formula: C18H20Cl4N4.HCl. Mole weight: 470.66. | |
NBI-30545 Quick inquiry Where to buy Suppliers range | NBI-30545 is a potent corticotropin-releasing factor-1 antagonist with proper lipophilicity (log D=2.78) and good solubility in water (>10mg/mL), and exhibited good plasma and brain exposure when given orally used for stress disorders. Synonyms: 3-(2,4-dimethoxyphenyl)-N-(2-methoxyethyl)-2,5-dimethyl-N-propylpyrazolo[1,5-a]pyrimidin-7-amine; NBI-30545; NBI30545; NBI 30545. Grades: >98%. CAS No. 195054-99-0. Molecular formula: C22H30N4O3. Mole weight: 398.507. | |
NBI-34041 Quick inquiry Where to buy Suppliers range | NBI-34041, also called as SB 723620, is potent and high-affinity corticotropin-releasing factor receptor 1 (CRF1) receptor antagonist. NBI-34041 shows that inhibition of the CRF system is a potential target for developing drug against depression and anxiety disorders. Synonyms: 1-(2,4-dichlorophenyl)-5-(heptan-4-yl)-7-methyl-4,5-dihydro-3H-2,2a,5,8-tetraazaacenaphthylene; NBI-34041; NBI 34041; NBI34041; SB-723620; SB723620; SB 723620. Grades: >98%. CAS No. 268545-87-5. Molecular formula: C22H26Cl2N4. Mole weight: 417.378. | |
NBI 35965 hydrochloride Quick inquiry Where to buy Suppliers range | NBI 35965 hydrochloride is a corticotropin-releasing factor receptor 1 antagonist. Some research shows that it has anxiolytic activity. Synonyms: NBI 35965 hydrochloride; NBI35965 hydrochloride; NBI-35965 hydrochloride; (7S)-6-(Cyclopropylmethyl)-2-(2,4-dichlorophenyl)-7-ethyl-7,8-dihydro-4-methyl-6H-1,3,6,8a-tetraazaacenaphthylene hydrochloride. Grades: ≥98% by HPLC. CAS No. 1782228-59-4. Molecular formula: C21H22Cl2N4.HCl. Mole weight: 437.79. | |
NBI 35965 mesylate Quick inquiry Where to buy Suppliers range | NBI 35965 is a selective corticotropin-releasing factor receptor 1 (CRF1) antagonist without activity against CRF2. It inhibited the stimulation of cAMP induced by sauvagine in CRF1 transfected cells and reduced stress-induced visceral hyperalgesia. Synonyms: (7S)-6-(Cyclopropylmethyl)-2-(2,4-dichlorophenyl)-7-ethyl-7,8-dihydro-4-methyl-6H-1,3,6,8a-tetraazaacenaphthylene monomethanesulfonate; (S)-5-(Cyclopropylmethyl)-1-(2,4-dichlorophenyl)-4-ethyl-7-methyl-4,5-dihydro-3H-2,2a,5,8-tetraazaacenaphthylene methanesulfonic acid. Grades: ≥95%. CAS No. 603151-83-3. Molecular formula: C21H22Cl2N4·CH3SO3H. Mole weight: 497.4. | |
NGD 98-2 hydrochloride Quick inquiry Where to buy Suppliers range | NGD 98-2 hydrochloride is a corticotropin-releasing factor receptor 1 antagonist. Synonyms: N-(1-Ethylpropyl)-3-methoxy-5-[2-methoxy-4-(trifluoromethoxy)phenyl]-6-methyl-2-pyrazinamine hydrochloride. Grades: ≥98% by HPLC. Molecular formula: C19H24F3N3O3.HCl. Mole weight: 435.87. | |
NVS-CRF38 Quick inquiry Where to buy Suppliers range | NVS-CRF38 is a novel corticotropin-releasing factor receptor 1 (CRF1) antagonist with low water solubility. Synonyms: NVS-CRF 38; NVS-CRF-38. Grades: >98%. CAS No. 1207258-55-6. Molecular formula: C19H21N5O2. Mole weight: 351.4. | |
Pexacerfont Quick inquiry Where to buy Suppliers range | Corticotropin-releasing factor (CRF), also known as corticotropin-releasing hormone, is an endogenous peptide hormone which is released in response to various triggers such as chronic stress. Pexacerfont is a potent and orally active CRF-1 antagonist trials for the treatment of anxiety disorders, and has also been proposed to be useful for the treatment of depression and irritable bowel syndrome. Uses: Crf-1 antagonist. Synonyms: BMS-562086; BMS 562086; BMS562086; BMS-562,086; BMS562,086; BMS 562,086; Pexacerfont.8-(6-Methoxy-2-methylpyridin-3-yl)-2,7-dimethyl-N-((1R)-1-methylpropyl)pyrazolo(1,5-a)-1,3,5-triazin-4-amine. Grades: ≥98%. CAS No. 459856-18-9. Molecular formula: C18H24N6O. Mole weight: 340.43. | |
Phe(2)-nle(4)-acth(1-24) Quick inquiry Where to buy Suppliers range | ACTH (1-24) is a fragment of the ACTH hormone, which stimulates the adrenal cortex and the secretion of glucocorticoids such as cortisol. Synonyms: 2-Phenylalanyl-4-norleucine-acth(1-24); ACTH (1-24), phe(2)-nle(4)-; alpha1-24-Corticotropin, 2-L-phenylalanine-4-L-norleucine-; (Phe2,Nle4)-ACTH (1-24) (human, bovine, rat). CAS No. 97773-00-7. Molecular formula: C137H212N40O30. Mole weight: 2899.40. | |
R-121919 Quick inquiry Where to buy Suppliers range | R-121919 is a potent orally active small-molecule Corticotropin-Releasing factor 1 (CRF1) receptor antagonist for the treatment of anxiety and depression, while having little affinity at the CRF2 receptor subtype. Synonyms: R121919; R-121919; R 121919; R121,919; R-121,919; R 121,919; NBI30775; NBI 30775; NBI-30775;3-(6-(DIMETHYLAMINO)-4-METHYLPYRIDIN-3-YL)-2,5-DIMETHYL-N,N-DIPROPYLPYRAZOLO[1,5-A]PYRIMIDIN-7-AMINE; 3-[6-(Dimethylamino)-4-methyl-3-pyridinyl]-2,5-dimethyl-N,N-dipropylpyrazolo[1,5-a]pyrimidin-7-amine. Grades: >98%. CAS No. 195055-03-9. Molecular formula: C22H32N6. Mole weight: 380.53. | |
R 121919 hydrochloride Quick inquiry Where to buy Suppliers range | R 121919 hydrochloride is a potent and orally available corticotropin releasing factor receptor1 (CRF1) antagonist. Synonyms: 3-[6-(Dimethylamino)-4-methyl-3-pyridinyl]-2,5-dimethyl-N,N-dipropylpyrazolo[1,5-a]pyrimidin-7-amine hydrochloride. Grades: ≥98% by HPLC. CAS No. 195055-66-4. Molecular formula: C22H32N6·HCl. Mole weight: 416.99. | |
Sauvagine Quick inquiry Where to buy Suppliers range | Sauvagine is a corticotropin-releasing factor (CRF) receptor agonist (Ki = 9.4, 9.9, and 3.8 nM for inhibition of 125I-[D-Tyr1]astressin binding to hCRF-R1, rCRF-R2a and mCRF-R2b, respectively). Synonyms: H-Pyr-Gly-Pro-Pro-Ile-Ser-Ile-Asp-Leu-Ser-Leu-Glu-Leu-Leu-Arg-Lys-Met-Ile-Glu-Ile-Glu-Lys-Gln-Glu-Lys-Glu-Lys-Gln-Gln-Ala-Ala-Asn-Asn-Arg-Leu-Leu-Leu-Asp-Thr-Ile-NH2. Grades: >96%. CAS No. 74434-59-6. Molecular formula: C202H346N56O63S. Mole weight: 4599.35. | |
Seractide Quick inquiry Where to buy Suppliers range | Seractide. Group: Heterocyclic Organic Compound. Alternative Names: Seractide; CORTICOTROPHIN; M.W. 4541.07 C207H308N56O58S; ADRENOCORTICOTROPIC HORMONE HUMAN; ACTH; Adrenocorticotropic Hormone human; ACTH 1-39; CORTICOTROPIN A. Grades: 96%. CAS No. 12279-41-3. Product ID: ACM12279413. Molecular formula: C207H308N56O58S. Mole weight: 4538.26. IUPAC Name: ACTH (1-39). Appearance: White lyophilised solid. | |
Seractide acetate Quick inquiry Where to buy Suppliers range | ACTH (1-39) is a potent agonist of melanocortin receptor 2 (MC2R) with an EC50 value of 57 pM in HeLa cells expressing the mouse receptor. Synonyms: 1-39-Corticotropin (human) (TFA); α(1-39) Corticotropin human (TFA); Acth, human (TFA); Adrenocorticotropic hormone, human (TFA); ACTH (1-39) (TFA); ACTH (1-39) trifluoroacetate salt; Adrenocorticotropic Hormone (ACTH) (1-39), human (TFA); Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-Asn-Gly-Ala-Glu-Asp-Glu-Ser-Ala-Glu-Ala-Phe-Pro-Leu-Glu-Phe.TFA. Grades: >98%. CAS No. 12279-41-3. Molecular formula: C207H308N56O58S.C2HF3O2. Mole weight: 4655.16. | |
SN 003 Quick inquiry Where to buy Suppliers range | SN 003 is a reversible corticotropin releasing factor receptor 1 (CRF1) antagonist (Ki = 3.4 and 7.9 nM at rat and human CRF1, respectively) that displays >1000-fold selectivity over CRF2 receptors. SN 003 was shown to inhibit CRF-induced ACTH release in vitro (IC50 = 241 nM). Synonyms: SN 003; SN003; SN-003; N-(4-Methoxy-2-methylphenyl)-1-[1-(methoxymethyl)propyl]-6-methyl-1H-1,2,3-triazolo[4,5-c]pyridin-4-amine; 1-(1-methoxybutan-2-yl)-N-(4-methoxy-2-methylphenyl)-6-methyltriazolo[4,5-c]pyridin-4-amine. Grades: ≥98% by HPLC. CAS No. 197801-88-0. Molecular formula: C19H25N5O2. Mole weight: 355.43. | |
SSR125543 Quick inquiry Where to buy Suppliers range | SSR125543 is a selective corticotropin-releasing factor 1 receptor (CRF1) antagonist with pKi value of 9.08 for native CRF1 receptor. It can prevent stress-induced cognitive deficit associated with hippocampal dysfunction. In Apr 2011, Phase-II for Major depressive disorder was discontinued. Uses: Major depressive disorder. Synonyms: SSR125543; SSR 125543; SSR-125543; SSR 125543A;321839-75-2(hydrochloride);(S)-4-(2-chloro-4-methoxy-5-methylphenyl)-N-(2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl)-5-methyl-N-(prop-2-yn-1-yl)thiazol-2-amine. Grades: 98%. CAS No. 752253-39-7. Molecular formula: C27H28ClFN2OS. Mole weight: 483.04. | |
SSR 125543A Quick inquiry Where to buy Suppliers range | SSR 125543A is a potent and orally bioactive corticotropin-releasing factor 1 receptor (CRF1) antagonist (pKi values of 8.73 and 9.08 for human cloned or native CRF1 receptors, respectively) with 1000-fold selectivity for CRF1 over CRF2α receptor and CRF binding protein. SSR 125543A exhibited antidepressant and anxiolytic properties in the Flinders Sensitive Line rats. Synonyms: SR-125543A; SR125543A; LS-150601; LS150601; LS 150601; 4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1S)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-prop-2-ynyl-1,3-thiazol-2-amine hydrochloride. Grades: 98%. CAS No. 321839-75-2. Molecular formula: C27H28ClFN2OS.HCl. Mole weight: 519.5. |